---
_id: '10866'
abstract:
- lang: eng
text: Recent discoveries have shown that, when two layers of van der Waals (vdW)
materials are superimposed with a relative twist angle between them, the electronic
properties of the coupled system can be dramatically altered. Here, we demonstrate
that a similar concept can be extended to the optics realm, particularly to propagating
phonon polaritons–hybrid light-matter interactions. To do this, we fabricate stacks
composed of two twisted slabs of a vdW crystal (α-MoO3) supporting anisotropic
phonon polaritons (PhPs), and image the propagation of the latter when launched
by localized sources. Our images reveal that, under a critical angle, the PhPs
isofrequency curve undergoes a topological transition, in which the propagation
of PhPs is strongly guided (canalization regime) along predetermined directions
without geometric spreading. These results demonstrate a new degree of freedom
(twist angle) for controlling the propagation of polaritons at the nanoscale with
potential for nanoimaging, (bio)-sensing, or heat management.
acknowledgement: "J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa
Program from the\r\nGovernment of the Principality of Asturias (nos. PA-18-PF-BP17-126
and PA20-PF-BP19-053,\r\nrespectively). J. M-S acknowledges financial support through
the Ramón y Cajal Program from\r\nthe Government of Spain (RYC2018-026196-I). A.Y.N.
acknowledges the Spanish Ministry of\r\nScience, Innovation and Universities (national
project no. MAT201788358-C3-3-R). P.A.-G.\r\nacknowledges support from the European
Research Council under starting grant no. 715496,\r\n2DNANOPTICA."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jiahua
full_name: Duan, Jiahua
last_name: Duan
- first_name: Nathaniel
full_name: Capote-Robayna, Nathaniel
last_name: Capote-Robayna
- first_name: Javier
full_name: Taboada-Gutiérrez, Javier
last_name: Taboada-Gutiérrez
- first_name: Gonzalo
full_name: Álvarez-Pérez, Gonzalo
last_name: Álvarez-Pérez
- first_name: Ivan
full_name: Prieto Gonzalez, Ivan
id: 2A307FE2-F248-11E8-B48F-1D18A9856A87
last_name: Prieto Gonzalez
orcid: 0000-0002-7370-5357
- first_name: Javier
full_name: Martín-Sánchez, Javier
last_name: Martín-Sánchez
- first_name: Alexey Y.
full_name: Nikitin, Alexey Y.
last_name: Nikitin
- first_name: Pablo
full_name: Alonso-González, Pablo
last_name: Alonso-González
citation:
ama: 'Duan J, Capote-Robayna N, Taboada-Gutiérrez J, et al. Twisted nano-optics:
Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano
Letters. 2020;20(7):5323-5329. doi:10.1021/acs.nanolett.0c01673'
apa: 'Duan, J., Capote-Robayna, N., Taboada-Gutiérrez, J., Álvarez-Pérez, G., Prieto
Gonzalez, I., Martín-Sánchez, J., … Alonso-González, P. (2020). Twisted nano-optics:
Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano
Letters. American Chemical Society. https://doi.org/10.1021/acs.nanolett.0c01673'
chicago: 'Duan, Jiahua, Nathaniel Capote-Robayna, Javier Taboada-Gutiérrez, Gonzalo
Álvarez-Pérez, Ivan Prieto Gonzalez, Javier Martín-Sánchez, Alexey Y. Nikitin,
and Pablo Alonso-González. “Twisted Nano-Optics: Manipulating Light at the Nanoscale
with Twisted Phonon Polaritonic Slabs.” Nano Letters. American Chemical
Society, 2020. https://doi.org/10.1021/acs.nanolett.0c01673.'
ieee: 'J. Duan et al., “Twisted nano-optics: Manipulating light at the nanoscale
with twisted phonon polaritonic slabs,” Nano Letters, vol. 20, no. 7. American
Chemical Society, pp. 5323–5329, 2020.'
ista: 'Duan J, Capote-Robayna N, Taboada-Gutiérrez J, Álvarez-Pérez G, Prieto Gonzalez
I, Martín-Sánchez J, Nikitin AY, Alonso-González P. 2020. Twisted nano-optics:
Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano
Letters. 20(7), 5323–5329.'
mla: 'Duan, Jiahua, et al. “Twisted Nano-Optics: Manipulating Light at the Nanoscale
with Twisted Phonon Polaritonic Slabs.” Nano Letters, vol. 20, no. 7, American
Chemical Society, 2020, pp. 5323–29, doi:10.1021/acs.nanolett.0c01673.'
short: J. Duan, N. Capote-Robayna, J. Taboada-Gutiérrez, G. Álvarez-Pérez, I. Prieto
Gonzalez, J. Martín-Sánchez, A.Y. Nikitin, P. Alonso-González, Nano Letters 20
(2020) 5323–5329.
date_created: 2022-03-18T11:37:38Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-09-05T12:05:58Z
day: '01'
department:
- _id: NanoFab
doi: 10.1021/acs.nanolett.0c01673
external_id:
arxiv:
- '2004.14599'
isi:
- '000548893200082'
pmid:
- '32530634'
intvolume: ' 20'
isi: 1
issue: '7'
keyword:
- Mechanical Engineering
- Condensed Matter Physics
- General Materials Science
- General Chemistry
- Bioengineering
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2004.14599
month: '07'
oa: 1
oa_version: Preprint
page: 5323-5329
pmid: 1
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
issn:
- 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon
polaritonic slabs'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 20
year: '2020'
...
---
_id: '13361'
abstract:
- lang: eng
text: "In nature, light is harvested by photoactive proteins to drive a range of
biological processes, including photosynthesis, phototaxis, vision, and ultimately
life. Bacteriorhodopsin, for example, is a protein embedded within archaeal cell
membranes that binds the chromophore retinal within its hydrophobic pocket. Exposure
to light triggers regioselective photoisomerization of the confined retinal, which
in turn initiates a cascade of conformational changes within the protein, triggering
proton flux against the concentration gradient, providing the microorganisms with
the energy to live. We are inspired by these functions in nature to harness light
energy using synthetic photoswitches under confinement. Like retinal, synthetic
photoswitches require some degree of conformational flexibility to isomerize.
In nature, the conformational change associated with retinal isomerization is
accommodated by the structural flexibility of the opsin host, yet it results in
steric communication between the chromophore and the protein. Similarly, we strive
to design systems wherein isomerization of confined photoswitches results in steric
communication between a photoswitch and its confining environment. To achieve
this aim, a balance must be struck between molecular crowding and conformational
freedom under confinement: too much crowding prevents switching, whereas too much
freedom resembles switching of isolated molecules in solution, preventing communication.\r\n\r\nIn
this Account, we discuss five classes of synthetic light-switchable compounds—diarylethenes,
anthracenes, azobenzenes, spiropyrans, and donor–acceptor Stenhouse adducts—comparing
their behaviors under confinement and in solution. The environments employed to
confine these photoswitches are diverse, ranging from planar surfaces to nanosized
cavities within coordination cages, nanoporous frameworks, and nanoparticle aggregates.
The trends that emerge are primarily dependent on the nature of the photoswitch
and not on the material used for confinement. In general, we find that photoswitches
requiring less conformational freedom for switching are, as expected, more straightforward
to isomerize reversibly under confinement. Because these compounds undergo only
small structural changes upon isomerization, however, switching does not propagate
into communication with their environment. Conversely, photoswitches that require
more conformational freedom are more challenging to switch under confinement but
also can influence system-wide behavior.\r\n\r\nAlthough we are primarily interested
in the effects of geometric constraints on photoswitching under confinement, additional
effects inevitably emerge when a compound is removed from solution and placed
within a new, more crowded environment. For instance, we have found that compounds
that convert to zwitterionic isomers upon light irradiation often experience stabilization
of these forms under confinement. This effect results from the mutual stabilization
of zwitterions that are brought into close proximity on surfaces or within cavities.
Furthermore, photoswitches can experience preorganization under confinement, influencing
the selectivity and efficiency of their photoreactions. Because intermolecular
interactions arising from confinement cannot be considered independently from
the effects of geometric constraints, we describe all confinement effects concurrently
throughout this Account."
article_processing_charge: No
article_type: original
author:
- first_name: Angela B.
full_name: Grommet, Angela B.
last_name: Grommet
- first_name: Lucia M.
full_name: Lee, Lucia M.
last_name: Lee
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Grommet AB, Lee LM, Klajn R. Molecular photoswitching in confined spaces. Accounts
of Chemical Research. 2020;53(11):2600-2610. doi:10.1021/acs.accounts.0c00434
apa: Grommet, A. B., Lee, L. M., & Klajn, R. (2020). Molecular photoswitching
in confined spaces. Accounts of Chemical Research. American Chemical Society.
https://doi.org/10.1021/acs.accounts.0c00434
chicago: Grommet, Angela B., Lucia M. Lee, and Rafal Klajn. “Molecular Photoswitching
in Confined Spaces.” Accounts of Chemical Research. American Chemical Society,
2020. https://doi.org/10.1021/acs.accounts.0c00434.
ieee: A. B. Grommet, L. M. Lee, and R. Klajn, “Molecular photoswitching in confined
spaces,” Accounts of Chemical Research, vol. 53, no. 11. American Chemical
Society, pp. 2600–2610, 2020.
ista: Grommet AB, Lee LM, Klajn R. 2020. Molecular photoswitching in confined spaces.
Accounts of Chemical Research. 53(11), 2600–2610.
mla: Grommet, Angela B., et al. “Molecular Photoswitching in Confined Spaces.” Accounts
of Chemical Research, vol. 53, no. 11, American Chemical Society, 2020, pp.
2600–10, doi:10.1021/acs.accounts.0c00434.
short: A.B. Grommet, L.M. Lee, R. Klajn, Accounts of Chemical Research 53 (2020)
2600–2610.
date_created: 2023-08-01T09:35:50Z
date_published: 2020-11-17T00:00:00Z
date_updated: 2024-10-14T12:12:31Z
day: '17'
doi: 10.1021/acs.accounts.0c00434
extern: '1'
external_id:
pmid:
- '32969638'
intvolume: ' 53'
issue: '11'
keyword:
- General Medicine
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/acs.accounts.0c00434
month: '11'
oa: 1
oa_version: Published Version
page: 2600-2610
pmid: 1
publication: Accounts of Chemical Research
publication_identifier:
eissn:
- 1520-4898
issn:
- 0001-4842
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular photoswitching in confined spaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2020'
...
---
_id: '13362'
abstract:
- lang: eng
text: Aggregation of organic molecules can drastically affect their physicochemical
properties. For instance, the optical properties of BODIPY dyes are inherently
related to the degree of aggregation and the mutual orientation of BODIPY units
within these aggregates. Whereas the noncovalent aggregation of various BODIPY
dyes has been studied in diverse media, the ill-defined nature of these aggregates
has made it difficult to elucidate the structure–property relationships. Here,
we studied the encapsulation of three structurally simple BODIPY derivatives within
the hydrophobic cavity of a water-soluble, flexible PdII6L4 coordination cage.
The cavity size allowed for the selective encapsulation of two dye molecules,
irrespective of the substitution pattern on the BODIPY core. Working with a model,
a pentamethyl-substituted derivative, we found that the mutual orientation of
two BODIPY units in the cage’s cavity was remarkably similar to that in the crystalline
state of the free dye, allowing us to isolate and characterize the smallest possible
noncovalent H-type BODIPY aggregate, namely, an H-dimer. Interestingly, a CF3-substituted
BODIPY, known for forming J-type aggregates, was also encapsulated as an H-dimer.
Taking advantage of the dynamic nature of encapsulation, we developed a system
in which reversible switching between H- and J-aggregates can be induced for multiple
cycles simply by addition and subsequent destruction of the cage. We expect that
the ability to rapidly and reversibly manipulate the optical properties of supramolecular
inclusion complexes in aqueous media will open up avenues for developing detection
systems that operate within biological environments.
article_processing_charge: No
article_type: original
author:
- first_name: Julius
full_name: Gemen, Julius
last_name: Gemen
- first_name: Johannes
full_name: Ahrens, Johannes
last_name: Ahrens
- first_name: Linda J. W.
full_name: Shimon, Linda J. W.
last_name: Shimon
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Gemen J, Ahrens J, Shimon LJW, Klajn R. Modulating the optical properties of
BODIPY dyes by noncovalent dimerization within a flexible coordination cage. Journal
of the American Chemical Society. 2020;142(41):17721-17729. doi:10.1021/jacs.0c08589
apa: Gemen, J., Ahrens, J., Shimon, L. J. W., & Klajn, R. (2020). Modulating
the optical properties of BODIPY dyes by noncovalent dimerization within a flexible
coordination cage. Journal of the American Chemical Society. American Chemical
Society. https://doi.org/10.1021/jacs.0c08589
chicago: Gemen, Julius, Johannes Ahrens, Linda J. W. Shimon, and Rafal Klajn. “Modulating
the Optical Properties of BODIPY Dyes by Noncovalent Dimerization within a Flexible
Coordination Cage.” Journal of the American Chemical Society. American
Chemical Society, 2020. https://doi.org/10.1021/jacs.0c08589.
ieee: J. Gemen, J. Ahrens, L. J. W. Shimon, and R. Klajn, “Modulating the optical
properties of BODIPY dyes by noncovalent dimerization within a flexible coordination
cage,” Journal of the American Chemical Society, vol. 142, no. 41. American
Chemical Society, pp. 17721–17729, 2020.
ista: Gemen J, Ahrens J, Shimon LJW, Klajn R. 2020. Modulating the optical properties
of BODIPY dyes by noncovalent dimerization within a flexible coordination cage.
Journal of the American Chemical Society. 142(41), 17721–17729.
mla: Gemen, Julius, et al. “Modulating the Optical Properties of BODIPY Dyes by
Noncovalent Dimerization within a Flexible Coordination Cage.” Journal of the
American Chemical Society, vol. 142, no. 41, American Chemical Society, 2020,
pp. 17721–29, doi:10.1021/jacs.0c08589.
short: J. Gemen, J. Ahrens, L.J.W. Shimon, R. Klajn, Journal of the American Chemical
Society 142 (2020) 17721–17729.
date_created: 2023-08-01T09:36:10Z
date_published: 2020-10-04T00:00:00Z
date_updated: 2024-10-14T12:12:41Z
day: '04'
doi: 10.1021/jacs.0c08589
extern: '1'
external_id:
pmid:
- '33006898'
intvolume: ' 142'
issue: '41'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/jacs.0c08589
month: '10'
oa: 1
oa_version: Published Version
page: 17721-17729
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modulating the optical properties of BODIPY dyes by noncovalent dimerization
within a flexible coordination cage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2020'
...
---
_id: '13363'
abstract:
- lang: eng
text: Temporal activation of biological processes by visible light and subsequent
return to an inactive state in the absence of light is an essential characteristic
of photoreceptor cells. Inspired by these phenomena, light-responsive materials
are very attractive due to the high spatiotemporal control of light irradiation,
with light being able to precisely orchestrate processes repeatedly over many
cycles. Herein, it is reported that light-driven proton transfer triggered by
a merocyanine-based photoacid can be used to modulate the permeability of pH-responsive
polymersomes through cyclic, temporally controlled protonation and deprotonation
of the polymersome membrane. The membranes can undergo repeated light-driven swelling–contraction
cycles without losing functional effectiveness. When applied to enzyme loaded-nanoreactors,
this membrane responsiveness is used for the reversible control of enzymatic reactions.
This combination of the merocyanine-based photoacid and pH-switchable nanoreactors
results in rapidly responding and versatile supramolecular systems successfully
used to switch enzymatic reactions ON and OFF on demand.
article_number: '2002135'
article_processing_charge: No
article_type: original
author:
- first_name: Silvia
full_name: Moreno, Silvia
last_name: Moreno
- first_name: Priyanka
full_name: Sharan, Priyanka
last_name: Sharan
- first_name: Johanna
full_name: Engelke, Johanna
last_name: Engelke
- first_name: Hannes
full_name: Gumz, Hannes
last_name: Gumz
- first_name: Susanne
full_name: Boye, Susanne
last_name: Boye
- first_name: Ulrich
full_name: Oertel, Ulrich
last_name: Oertel
- first_name: Peng
full_name: Wang, Peng
last_name: Wang
- first_name: Susanta
full_name: Banerjee, Susanta
last_name: Banerjee
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Brigitte
full_name: Voit, Brigitte
last_name: Voit
- first_name: Albena
full_name: Lederer, Albena
last_name: Lederer
- first_name: Dietmar
full_name: Appelhans, Dietmar
last_name: Appelhans
citation:
ama: Moreno S, Sharan P, Engelke J, et al. Light‐driven proton transfer for cyclic
and temporal switching of enzymatic nanoreactors. Small. 2020;16(37). doi:10.1002/smll.202002135
apa: Moreno, S., Sharan, P., Engelke, J., Gumz, H., Boye, S., Oertel, U., … Appelhans,
D. (2020). Light‐driven proton transfer for cyclic and temporal switching of enzymatic
nanoreactors. Small. Wiley. https://doi.org/10.1002/smll.202002135
chicago: Moreno, Silvia, Priyanka Sharan, Johanna Engelke, Hannes Gumz, Susanne
Boye, Ulrich Oertel, Peng Wang, et al. “Light‐driven Proton Transfer for Cyclic
and Temporal Switching of Enzymatic Nanoreactors.” Small. Wiley, 2020.
https://doi.org/10.1002/smll.202002135.
ieee: S. Moreno et al., “Light‐driven proton transfer for cyclic and temporal
switching of enzymatic nanoreactors,” Small, vol. 16, no. 37. Wiley, 2020.
ista: Moreno S, Sharan P, Engelke J, Gumz H, Boye S, Oertel U, Wang P, Banerjee
S, Klajn R, Voit B, Lederer A, Appelhans D. 2020. Light‐driven proton transfer
for cyclic and temporal switching of enzymatic nanoreactors. Small. 16(37), 2002135.
mla: Moreno, Silvia, et al. “Light‐driven Proton Transfer for Cyclic and Temporal
Switching of Enzymatic Nanoreactors.” Small, vol. 16, no. 37, 2002135,
Wiley, 2020, doi:10.1002/smll.202002135.
short: S. Moreno, P. Sharan, J. Engelke, H. Gumz, S. Boye, U. Oertel, P. Wang, S.
Banerjee, R. Klajn, B. Voit, A. Lederer, D. Appelhans, Small 16 (2020).
date_created: 2023-08-01T09:36:48Z
date_published: 2020-08-11T00:00:00Z
date_updated: 2023-08-07T10:11:41Z
day: '11'
doi: 10.1002/smll.202002135
extern: '1'
external_id:
pmid:
- '32783385'
intvolume: ' 16'
issue: '37'
keyword:
- Biomaterials
- Biotechnology
- General Materials Science
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/smll.202002135
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Small
publication_identifier:
eissn:
- 1613-6829
issn:
- 1613-6810
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Light‐driven proton transfer for cyclic and temporal switching of enzymatic
nanoreactors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2020'
...
---
_id: '13364'
abstract:
- lang: eng
text: Photochromic molecules undergo reversible isomerization upon irradiation with
light at different wavelengths, a process that can alter their physical and chemical
properties. For instance, dihydropyrene (DHP) is a deep-colored compound that
isomerizes to light-brown cyclophanediene (CPD) upon irradiation with visible
light. CPD can then isomerize back to DHP upon irradiation with UV light or thermally
in the dark. Conversion between DHP and CPD is thought to proceed via a biradical
intermediate; bimolecular events involving this unstable intermediate thus result
in rapid decomposition and poor cycling performance. Here, we show that the reversible
isomerization of DHP can be stabilized upon confinement within a PdII6L4 coordination
cage. By protecting this reactive intermediate using the cage, each isomerization
reaction proceeds to higher yield, which significantly decreases the fatigue experienced
by the system upon repeated photocycling. Although molecular confinement is known
to help stabilize reactive species, this effect is not typically employed to protect
reactive intermediates and thus improve reaction yields. We envisage that performing
reactions under confinement will not only improve the cyclic performance of photochromic
molecules, but may also increase the amount of product obtainable from traditionally
low-yielding organic reactions.
article_processing_charge: No
article_type: original
author:
- first_name: Martina
full_name: Canton, Martina
last_name: Canton
- first_name: Angela B.
full_name: Grommet, Angela B.
last_name: Grommet
- first_name: Luca
full_name: Pesce, Luca
last_name: Pesce
- first_name: Julius
full_name: Gemen, Julius
last_name: Gemen
- first_name: Shiming
full_name: Li, Shiming
last_name: Li
- first_name: Yael
full_name: Diskin-Posner, Yael
last_name: Diskin-Posner
- first_name: Alberto
full_name: Credi, Alberto
last_name: Credi
- first_name: Giovanni M.
full_name: Pavan, Giovanni M.
last_name: Pavan
- first_name: Joakim
full_name: Andréasson, Joakim
last_name: Andréasson
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Canton M, Grommet AB, Pesce L, et al. Improving fatigue resistance of dihydropyrene
by encapsulation within a coordination cage. Journal of the American Chemical
Society. 2020;142(34):14557-14565. doi:10.1021/jacs.0c06146
apa: Canton, M., Grommet, A. B., Pesce, L., Gemen, J., Li, S., Diskin-Posner, Y.,
… Klajn, R. (2020). Improving fatigue resistance of dihydropyrene by encapsulation
within a coordination cage. Journal of the American Chemical Society. American
Chemical Society. https://doi.org/10.1021/jacs.0c06146
chicago: Canton, Martina, Angela B. Grommet, Luca Pesce, Julius Gemen, Shiming Li,
Yael Diskin-Posner, Alberto Credi, Giovanni M. Pavan, Joakim Andréasson, and Rafal
Klajn. “Improving Fatigue Resistance of Dihydropyrene by Encapsulation within
a Coordination Cage.” Journal of the American Chemical Society. American
Chemical Society, 2020. https://doi.org/10.1021/jacs.0c06146.
ieee: M. Canton et al., “Improving fatigue resistance of dihydropyrene by
encapsulation within a coordination cage,” Journal of the American Chemical
Society, vol. 142, no. 34. American Chemical Society, pp. 14557–14565, 2020.
ista: Canton M, Grommet AB, Pesce L, Gemen J, Li S, Diskin-Posner Y, Credi A, Pavan
GM, Andréasson J, Klajn R. 2020. Improving fatigue resistance of dihydropyrene
by encapsulation within a coordination cage. Journal of the American Chemical
Society. 142(34), 14557–14565.
mla: Canton, Martina, et al. “Improving Fatigue Resistance of Dihydropyrene by Encapsulation
within a Coordination Cage.” Journal of the American Chemical Society,
vol. 142, no. 34, American Chemical Society, 2020, pp. 14557–65, doi:10.1021/jacs.0c06146.
short: M. Canton, A.B. Grommet, L. Pesce, J. Gemen, S. Li, Y. Diskin-Posner, A.
Credi, G.M. Pavan, J. Andréasson, R. Klajn, Journal of the American Chemical Society
142 (2020) 14557–14565.
date_created: 2023-08-01T09:36:59Z
date_published: 2020-08-14T00:00:00Z
date_updated: 2023-08-07T10:15:38Z
day: '14'
doi: 10.1021/jacs.0c06146
extern: '1'
external_id:
pmid:
- '32791832'
intvolume: ' 142'
issue: '34'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/jacs.0c06146
month: '08'
oa: 1
oa_version: Published Version
page: 14557-14565
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improving fatigue resistance of dihydropyrene by encapsulation within a coordination
cage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2020'
...
---
_id: '13365'
abstract:
- lang: eng
text: Photoswitchable molecules are employed for many applications, from the development
of active materials to the design of stimuli-responsive molecular systems and
light-powered molecular machines. To fully exploit their potential, we must learn
ways to control the mechanism and kinetics of their photoinduced isomerization.
One possible strategy involves confinement of photoresponsive switches such as
azobenzenes or spiropyrans within crowded molecular environments, which may allow
control over their light-induced conversion. However, the molecular factors that
influence and control the switching process under realistic conditions and within
dynamic molecular regimes often remain difficult to ascertain. As a case study,
here we have employed molecular models to probe the isomerization of azobenzene
guests within a Pd(II)-based coordination cage host in water. Atomistic molecular
dynamics and metadynamics simulations allow us to characterize the flexibility
of the cage in the solvent, the (rare) guest encapsulation and release events,
and the relative probability/kinetics of light-induced isomerization of azobenzene
analogues in these host–guest systems. In this way, we can reconstruct the mechanism
of azobenzene switching inside the cage cavity and explore key molecular factors
that may control this event. We obtain a molecular-level insight on the effects
of crowding and host–guest interactions on azobenzene isomerization. The detailed
picture elucidated by this study may enable the rational design of photoswitchable
systems whose reactivity can be controlled via host–guest interactions.
article_processing_charge: No
article_type: original
author:
- first_name: Luca
full_name: Pesce, Luca
last_name: Pesce
- first_name: Claudio
full_name: Perego, Claudio
last_name: Perego
- first_name: Angela B.
full_name: Grommet, Angela B.
last_name: Grommet
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Giovanni M.
full_name: Pavan, Giovanni M.
last_name: Pavan
citation:
ama: Pesce L, Perego C, Grommet AB, Klajn R, Pavan GM. Molecular factors controlling
the isomerization of Azobenzenes in the cavity of a flexible coordination cage.
Journal of the American Chemical Society. 2020;142(21):9792-9802. doi:10.1021/jacs.0c03444
apa: Pesce, L., Perego, C., Grommet, A. B., Klajn, R., & Pavan, G. M. (2020).
Molecular factors controlling the isomerization of Azobenzenes in the cavity of
a flexible coordination cage. Journal of the American Chemical Society.
American Chemical Society. https://doi.org/10.1021/jacs.0c03444
chicago: Pesce, Luca, Claudio Perego, Angela B. Grommet, Rafal Klajn, and Giovanni
M. Pavan. “Molecular Factors Controlling the Isomerization of Azobenzenes in the
Cavity of a Flexible Coordination Cage.” Journal of the American Chemical Society.
American Chemical Society, 2020. https://doi.org/10.1021/jacs.0c03444.
ieee: L. Pesce, C. Perego, A. B. Grommet, R. Klajn, and G. M. Pavan, “Molecular
factors controlling the isomerization of Azobenzenes in the cavity of a flexible
coordination cage,” Journal of the American Chemical Society, vol. 142,
no. 21. American Chemical Society, pp. 9792–9802, 2020.
ista: Pesce L, Perego C, Grommet AB, Klajn R, Pavan GM. 2020. Molecular factors
controlling the isomerization of Azobenzenes in the cavity of a flexible coordination
cage. Journal of the American Chemical Society. 142(21), 9792–9802.
mla: Pesce, Luca, et al. “Molecular Factors Controlling the Isomerization of Azobenzenes
in the Cavity of a Flexible Coordination Cage.” Journal of the American Chemical
Society, vol. 142, no. 21, American Chemical Society, 2020, pp. 9792–802,
doi:10.1021/jacs.0c03444.
short: L. Pesce, C. Perego, A.B. Grommet, R. Klajn, G.M. Pavan, Journal of the American
Chemical Society 142 (2020) 9792–9802.
date_created: 2023-08-01T09:37:12Z
date_published: 2020-04-30T00:00:00Z
date_updated: 2023-08-07T10:18:53Z
day: '30'
doi: 10.1021/jacs.0c03444
extern: '1'
external_id:
pmid:
- '32353237'
intvolume: ' 142'
issue: '21'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/jacs.0c03444
month: '04'
oa: 1
oa_version: Published Version
page: 9792-9802
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular factors controlling the isomerization of Azobenzenes in the cavity
of a flexible coordination cage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2020'
...
---
_id: '15142'
abstract:
- lang: eng
text: Bacteria and archaea employ CRISPR (clustered, regularly, interspaced, short
palindromic repeats)-Cas (CRISPR-associated) systems as a type of adaptive immunity
to target and degrade foreign nucleic acids. While a myriad of CRISPR-Cas systems
have been identified to date, type I-C is one of the most commonly found subtypes
in nature. Interestingly, the type I-C system employs a minimal Cascade effector
complex, which encodes only three unique subunits in its operon. Here, we present
a 3.1 Å resolution cryo-EM structure of the Desulfovibrio vulgaris
type I-C Cascade, revealing the molecular mechanisms that underlie RNA-directed
complex assembly. We demonstrate how this minimal Cascade utilizes previously
overlooked, non-canonical small subunits to stabilize R-loop formation. Furthermore,
we describe putative PAM and Cas3 binding sites. These findings provide the structural
basis for harnessing the type I-C Cascade as a genome-engineering tool.
article_number: '5931'
article_processing_charge: Yes
article_type: original
author:
- first_name: Roisin E.
full_name: O’Brien, Roisin E.
last_name: O’Brien
- first_name: Inês C.
full_name: Santos, Inês C.
last_name: Santos
- first_name: Daniel
full_name: Wrapp, Daniel
last_name: Wrapp
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Evan A.
full_name: Schwartz, Evan A.
last_name: Schwartz
- first_name: Jennifer S.
full_name: Brodbelt, Jennifer S.
last_name: Brodbelt
- first_name: David W.
full_name: Taylor, David W.
last_name: Taylor
citation:
ama: O’Brien RE, Santos IC, Wrapp D, et al. Structural basis for assembly of non-canonical
small subunits into type I-C Cascade. Nature Communications. 2020;11. doi:10.1038/s41467-020-19785-8
apa: O’Brien, R. E., Santos, I. C., Wrapp, D., Bravo, J. P. K., Schwartz, E. A.,
Brodbelt, J. S., & Taylor, D. W. (2020). Structural basis for assembly of
non-canonical small subunits into type I-C Cascade. Nature Communications.
Springer Nature. https://doi.org/10.1038/s41467-020-19785-8
chicago: O’Brien, Roisin E., Inês C. Santos, Daniel Wrapp, Jack Peter Kelly Bravo,
Evan A. Schwartz, Jennifer S. Brodbelt, and David W. Taylor. “Structural Basis
for Assembly of Non-Canonical Small Subunits into Type I-C Cascade.” Nature
Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-020-19785-8.
ieee: R. E. O’Brien et al., “Structural basis for assembly of non-canonical
small subunits into type I-C Cascade,” Nature Communications, vol. 11.
Springer Nature, 2020.
ista: O’Brien RE, Santos IC, Wrapp D, Bravo JPK, Schwartz EA, Brodbelt JS, Taylor
DW. 2020. Structural basis for assembly of non-canonical small subunits into type
I-C Cascade. Nature Communications. 11, 5931.
mla: O’Brien, Roisin E., et al. “Structural Basis for Assembly of Non-Canonical
Small Subunits into Type I-C Cascade.” Nature Communications, vol. 11,
5931, Springer Nature, 2020, doi:10.1038/s41467-020-19785-8.
short: R.E. O’Brien, I.C. Santos, D. Wrapp, J.P.K. Bravo, E.A. Schwartz, J.S. Brodbelt,
D.W. Taylor, Nature Communications 11 (2020).
date_created: 2024-03-20T10:43:07Z
date_published: 2020-11-23T00:00:00Z
date_updated: 2024-06-04T05:52:51Z
day: '23'
doi: 10.1038/s41467-020-19785-8
extern: '1'
external_id:
pmid:
- '33230133'
intvolume: ' 11'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41467-020-19785-8
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural basis for assembly of non-canonical small subunits into type I-C
Cascade
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2020'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10341'
abstract:
- lang: eng
text: Tracing the motion of macromolecules, viruses, and nanoparticles adsorbed
onto cell membranes is currently the most direct way of probing the complex dynamic
interactions behind vital biological processes, including cell signalling, trafficking,
and viral infection. The resulting trajectories are usually consistent with some
type of anomalous diffusion, but the molecular origins behind the observed anomalous
behaviour are usually not obvious. Here we use coarse-grained molecular dynamics
simulations to help identify the physical mechanisms that can give rise to experimentally
observed trajectories of nanoscopic objects moving on biological membranes. We
find that diffusion on membranes of high fluidities typically results in normal
diffusion of the adsorbed nanoparticle, irrespective of the concentration of receptors,
receptor clustering, or multivalent interactions between the particle and membrane
receptors. Gel-like membranes on the other hand result in anomalous diffusion
of the particle, which becomes more pronounced at higher receptor concentrations.
This anomalous diffusion is characterised by local particle trapping in the regions
of high receptor concentrations and fast hopping between such regions. The normal
diffusion is recovered in the limit where the gel membrane is saturated with receptors.
We conclude that hindered receptor diffusivity can be a common reason behind the
observed anomalous diffusion of viruses, vesicles, and nanoparticles adsorbed
on cell and model membranes. Our results enable direct comparison with experiments
and offer a new route for interpreting motility experiments on cell membranes.
acknowledgement: We thank Jessica McQuade for her input at the start of the project.
We acknowledge support from the ERASMUS Placement Programme (V. E. D.), the UCL
Institute for the Physics of Living Systems (V. E. D. and A. Š.), the UCL Global
Engagement Fund (L. M. C. J.), and the Royal Society (A. Š.).
article_processing_charge: No
article_type: original
author:
- first_name: V. E.
full_name: Debets, V. E.
last_name: Debets
- first_name: L. M. C.
full_name: Janssen, L. M. C.
last_name: Janssen
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: Debets VE, Janssen LMC, Šarić A. Characterising the diffusion of biological
nanoparticles on fluid and cross-linked membranes. Soft Matter. 2020;16(47):10628-10639.
doi:10.1039/d0sm00712a
apa: Debets, V. E., Janssen, L. M. C., & Šarić, A. (2020). Characterising the
diffusion of biological nanoparticles on fluid and cross-linked membranes. Soft
Matter. Royal Society of Chemistry. https://doi.org/10.1039/d0sm00712a
chicago: Debets, V. E., L. M. C. Janssen, and Anđela Šarić. “Characterising the
Diffusion of Biological Nanoparticles on Fluid and Cross-Linked Membranes.” Soft
Matter. Royal Society of Chemistry, 2020. https://doi.org/10.1039/d0sm00712a.
ieee: V. E. Debets, L. M. C. Janssen, and A. Šarić, “Characterising the diffusion
of biological nanoparticles on fluid and cross-linked membranes,” Soft Matter,
vol. 16, no. 47. Royal Society of Chemistry, pp. 10628–10639, 2020.
ista: Debets VE, Janssen LMC, Šarić A. 2020. Characterising the diffusion of biological
nanoparticles on fluid and cross-linked membranes. Soft Matter. 16(47), 10628–10639.
mla: Debets, V. E., et al. “Characterising the Diffusion of Biological Nanoparticles
on Fluid and Cross-Linked Membranes.” Soft Matter, vol. 16, no. 47, Royal
Society of Chemistry, 2020, pp. 10628–39, doi:10.1039/d0sm00712a.
short: V.E. Debets, L.M.C. Janssen, A. Šarić, Soft Matter 16 (2020) 10628–10639.
date_created: 2021-11-26T06:29:41Z
date_published: 2020-10-06T00:00:00Z
date_updated: 2024-10-16T12:53:17Z
day: '06'
doi: 10.1039/d0sm00712a
extern: '1'
external_id:
pmid:
- '33084724'
intvolume: ' 16'
issue: '47'
keyword:
- condensed matter physics
- general chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/10.1101/2020.05.01.071761v1
month: '10'
oa: 1
oa_version: Published Version
page: 10628-10639
pmid: 1
publication: Soft Matter
publication_identifier:
issn:
- 1744-683X
- 1744-6848
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Characterising the diffusion of biological nanoparticles on fluid and cross-linked
membranes
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 16
year: '2020'
...
---
_id: '10350'
abstract:
- lang: eng
text: The misfolding and aberrant aggregation of proteins into fibrillar structures
is a key factor in some of the most prevalent human diseases, including diabetes
and dementia. Low molecular weight oligomers are thought to be a central factor
in the pathology of these diseases, as well as critical intermediates in the fibril
formation process, and as such have received much recent attention. Moreover,
on-pathway oligomeric intermediates are potential targets for therapeutic strategies
aimed at interrupting the fibril formation process. However, a consistent framework
for distinguishing on-pathway from off-pathway oligomers has hitherto been lacking
and, in particular, no consensus definition of on- and off-pathway oligomers is
available. In this paper, we argue that a non-binary definition of oligomers'
contribution to fibril-forming pathways may be more informative and we suggest
a quantitative framework, in which each oligomeric species is assigned a value
between 0 and 1 describing its relative contribution to the formation of fibrils.
First, we clarify the distinction between oligomers and fibrils, and then we use
the formalism of reaction networks to develop a general definition for on-pathway
oligomers, that yields meaningful classifications in the context of amyloid formation.
By applying these concepts to Monte Carlo simulations of a minimal aggregating
system, and by revisiting several previous studies of amyloid oligomers in light
of our new framework, we demonstrate how to perform these classifications in practice.
For each oligomeric species we obtain the degree to which it is on-pathway, highlighting
the most effective pharmaceutical targets for the inhibition of amyloid fibril
formation.
acknowledgement: We are grateful to the Schiff Foundation (AJD), Peterhouse, Cambridge
(TCTM), the Swiss National Science foundation (TCTM), Ramon Jenkins Fellowship,
Sidney Sussex, Cambridge (GM), the Royal Society (AŠ), the Academy of Medical Sciences
and Wellcome Trust (AŠ), the Danish Research Council (MK), the Lundbeck Foundation
(MK), the Swedish Research Council (SL), the Wellcome Trust (TPJK), the Cambridge
Centre for Misfolding Diseases (TPJK), the BBSRC (TPJK), the Frances and Augustus
Newman Foundation (TPJK) for financial support. The research leading to these results
has received funding from the European Research Council under the European Union's
Seventh Framework Programme (FP7/2007-2013) through the ERC grants PhysProt (agreement
no. 337969), MAMBA (agreement no. 340890) and NovoNordiskFonden (SL).
article_processing_charge: No
article_type: original
author:
- first_name: Alexander J.
full_name: Dear, Alexander J.
last_name: Dear
- first_name: Georg
full_name: Meisl, Georg
last_name: Meisl
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Thomas C. T.
full_name: Michaels, Thomas C. T.
last_name: Michaels
- first_name: Magnus
full_name: Kjaergaard, Magnus
last_name: Kjaergaard
- first_name: Sara
full_name: Linse, Sara
last_name: Linse
- first_name: Tuomas P. J.
full_name: Knowles, Tuomas P. J.
last_name: Knowles
citation:
ama: Dear AJ, Meisl G, Šarić A, et al. Identification of on- and off-pathway oligomers
in amyloid fibril formation. Chemical Science. 2020;11(24):6236-6247. doi:10.1039/c9sc06501f
apa: Dear, A. J., Meisl, G., Šarić, A., Michaels, T. C. T., Kjaergaard, M., Linse,
S., & Knowles, T. P. J. (2020). Identification of on- and off-pathway oligomers
in amyloid fibril formation. Chemical Science. Royal Society of Chemistry.
https://doi.org/10.1039/c9sc06501f
chicago: Dear, Alexander J., Georg Meisl, Anđela Šarić, Thomas C. T. Michaels, Magnus
Kjaergaard, Sara Linse, and Tuomas P. J. Knowles. “Identification of On- and off-Pathway
Oligomers in Amyloid Fibril Formation.” Chemical Science. Royal Society
of Chemistry, 2020. https://doi.org/10.1039/c9sc06501f.
ieee: A. J. Dear et al., “Identification of on- and off-pathway oligomers
in amyloid fibril formation,” Chemical Science, vol. 11, no. 24. Royal
Society of Chemistry, pp. 6236–6247, 2020.
ista: Dear AJ, Meisl G, Šarić A, Michaels TCT, Kjaergaard M, Linse S, Knowles TPJ.
2020. Identification of on- and off-pathway oligomers in amyloid fibril formation.
Chemical Science. 11(24), 6236–6247.
mla: Dear, Alexander J., et al. “Identification of On- and off-Pathway Oligomers
in Amyloid Fibril Formation.” Chemical Science, vol. 11, no. 24, Royal
Society of Chemistry, 2020, pp. 6236–47, doi:10.1039/c9sc06501f.
short: A.J. Dear, G. Meisl, A. Šarić, T.C.T. Michaels, M. Kjaergaard, S. Linse,
T.P.J. Knowles, Chemical Science 11 (2020) 6236–6247.
date_created: 2021-11-26T09:08:19Z
date_published: 2020-06-08T00:00:00Z
date_updated: 2021-11-26T11:21:20Z
day: '08'
doi: 10.1039/c9sc06501f
extern: '1'
external_id:
pmid:
- '32953019'
intvolume: ' 11'
issue: '24'
keyword:
- general chemistry
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/3.0/
main_file_link:
- open_access: '1'
url: https://pubs.rsc.org/en/content/articlehtml/2020/sc/c9sc06501f
month: '06'
oa: 1
oa_version: Published Version
page: 6236-6247
pmid: 1
publication: Chemical Science
publication_identifier:
eissn:
- 2041-6539
issn:
- 2041-6520
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Identification of on- and off-pathway oligomers in amyloid fibril formation
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/3.0/legalcode
name: Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)
short: CC BY-NC (3.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 11
year: '2020'
...
---
_id: '10351'
abstract:
- lang: eng
text: Oligomeric species populated during the aggregation of the Aβ42 peptide have
been identified as potent cytotoxins linked to Alzheimer’s disease, but the fundamental
molecular pathways that control their dynamics have yet to be elucidated. By developing
a general approach that combines theory, experiment and simulation, we reveal,
in molecular detail, the mechanisms of Aβ42 oligomer dynamics during amyloid fibril
formation. Even though all mature amyloid fibrils must originate as oligomers,
we found that most Aβ42 oligomers dissociate into their monomeric precursors without
forming new fibrils. Only a minority of oligomers converts into fibrillar structures.
Moreover, the heterogeneous ensemble of oligomeric species interconverts on timescales
comparable to those of aggregation. Our results identify fundamentally new steps
that could be targeted by therapeutic interventions designed to combat protein
misfolding diseases.
acknowledgement: We acknowledge support from Peterhouse (T.C.T.M.), the Swiss National
Science foundation (T.C.T.M.), the Royal Society (A.Š.), the Academy of Medical
Sciences (A.Š.), the UCL Institute for the Physics of Living Systems (S.C.), Sidney
Sussex College (G.M.), the Wellcome Trust (A.Š., M.V., C.M.D. and T.P.J.K.), the
Schiff Foundation (A.J.D.), the Cambridge Centre for Misfolding Diseases (M.V.,
C.M.D. and T.P.J.K.), the BBSRC (C.M.D. and T.P.J.K.), the Frances and Augustus
Newman Foundation (T.P.J.K.), the Swedish Research Council (S.L.) and the ERC grant
MAMBA (S.L., agreement no. 340890). The research that led to these results received
funding from the European Research Council under the European Union’s Seventh Framework
Programme (FP7/2007-2013) through the ERC grant PhysProt (agreement no. 337969).
article_processing_charge: No
article_type: original
author:
- first_name: Thomas C. T.
full_name: Michaels, Thomas C. T.
last_name: Michaels
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Samo
full_name: Curk, Samo
last_name: Curk
- first_name: Katja
full_name: Bernfur, Katja
last_name: Bernfur
- first_name: Paolo
full_name: Arosio, Paolo
last_name: Arosio
- first_name: Georg
full_name: Meisl, Georg
last_name: Meisl
- first_name: Alexander J.
full_name: Dear, Alexander J.
last_name: Dear
- first_name: Samuel I. A.
full_name: Cohen, Samuel I. A.
last_name: Cohen
- first_name: Christopher M.
full_name: Dobson, Christopher M.
last_name: Dobson
- first_name: Michele
full_name: Vendruscolo, Michele
last_name: Vendruscolo
- first_name: Sara
full_name: Linse, Sara
last_name: Linse
- first_name: Tuomas P. J.
full_name: Knowles, Tuomas P. J.
last_name: Knowles
citation:
ama: Michaels TCT, Šarić A, Curk S, et al. Dynamics of oligomer populations formed
during the aggregation of Alzheimer’s Aβ42 peptide. Nature Chemistry. 2020;12(5):445-451.
doi:10.1038/s41557-020-0452-1
apa: Michaels, T. C. T., Šarić, A., Curk, S., Bernfur, K., Arosio, P., Meisl, G.,
… Knowles, T. P. J. (2020). Dynamics of oligomer populations formed during the
aggregation of Alzheimer’s Aβ42 peptide. Nature Chemistry. Springer Nature.
https://doi.org/10.1038/s41557-020-0452-1
chicago: Michaels, Thomas C. T., Anđela Šarić, Samo Curk, Katja Bernfur, Paolo Arosio,
Georg Meisl, Alexander J. Dear, et al. “Dynamics of Oligomer Populations Formed
during the Aggregation of Alzheimer’s Aβ42 Peptide.” Nature Chemistry.
Springer Nature, 2020. https://doi.org/10.1038/s41557-020-0452-1.
ieee: T. C. T. Michaels et al., “Dynamics of oligomer populations formed
during the aggregation of Alzheimer’s Aβ42 peptide,” Nature Chemistry,
vol. 12, no. 5. Springer Nature, pp. 445–451, 2020.
ista: Michaels TCT, Šarić A, Curk S, Bernfur K, Arosio P, Meisl G, Dear AJ, Cohen
SIA, Dobson CM, Vendruscolo M, Linse S, Knowles TPJ. 2020. Dynamics of oligomer
populations formed during the aggregation of Alzheimer’s Aβ42 peptide. Nature
Chemistry. 12(5), 445–451.
mla: Michaels, Thomas C. T., et al. “Dynamics of Oligomer Populations Formed during
the Aggregation of Alzheimer’s Aβ42 Peptide.” Nature Chemistry, vol. 12,
no. 5, Springer Nature, 2020, pp. 445–51, doi:10.1038/s41557-020-0452-1.
short: T.C.T. Michaels, A. Šarić, S. Curk, K. Bernfur, P. Arosio, G. Meisl, A.J.
Dear, S.I.A. Cohen, C.M. Dobson, M. Vendruscolo, S. Linse, T.P.J. Knowles, Nature
Chemistry 12 (2020) 445–451.
date_created: 2021-11-26T09:15:13Z
date_published: 2020-04-13T00:00:00Z
date_updated: 2021-11-26T11:21:08Z
day: '13'
doi: 10.1038/s41557-020-0452-1
extern: '1'
external_id:
pmid:
- '32303714'
intvolume: ' 12'
issue: '5'
keyword:
- general chemical engineering
- general chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/10.1101/2020.01.08.897488
month: '04'
oa: 1
oa_version: None
page: 445-451
pmid: 1
publication: Nature Chemistry
publication_identifier:
eissn:
- 1755-4349
issn:
- 1755-4330
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41557-020-0468-6
scopus_import: '1'
status: public
title: Dynamics of oligomer populations formed during the aggregation of Alzheimer’s
Aβ42 peptide
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 12
year: '2020'
...
---
_id: '8568'
abstract:
- lang: eng
text: Aqueous iodine based electrochemical energy storage is considered a potential
candidate to improve sustainability and performance of current battery and supercapacitor
technology. It harnesses the redox activity of iodide, iodine, and polyiodide
species in the confined geometry of nanoporous carbon electrodes. However, current
descriptions of the electrochemical reaction mechanism to interconvert these species
are elusive. Here we show that electrochemical oxidation of iodide in nanoporous
carbons forms persistent solid iodine deposits. Confinement slows down dissolution
into triiodide and pentaiodide, responsible for otherwise significant self-discharge
via shuttling. The main tools for these insights are in situ Raman spectroscopy
and in situ small and wide-angle X-ray scattering (in situ SAXS/WAXS). In situ
Raman confirms the reversible formation of triiodide and pentaiodide. In situ
SAXS/WAXS indicates remarkable amounts of solid iodine deposited in the carbon
nanopores. Combined with stochastic modeling, in situ SAXS allows quantifying
the solid iodine volume fraction and visualizing the iodine structure on 3D lattice
models at the sub-nanometer scale. Based on the derived mechanism, we demonstrate
strategies for improved iodine pore filling capacity and prevention of self-discharge,
applicable to hybrid supercapacitors and batteries.
article_number: '4838'
article_processing_charge: No
article_type: original
author:
- first_name: Christian
full_name: Prehal, Christian
last_name: Prehal
- first_name: Harald
full_name: Fitzek, Harald
last_name: Fitzek
- first_name: Gerald
full_name: Kothleitner, Gerald
last_name: Kothleitner
- first_name: Volker
full_name: Presser, Volker
last_name: Presser
- first_name: Bernhard
full_name: Gollas, Bernhard
last_name: Gollas
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Qamar
full_name: Abbas, Qamar
last_name: Abbas
citation:
ama: Prehal C, Fitzek H, Kothleitner G, et al. Persistent and reversible solid iodine
electrodeposition in nanoporous carbons. Nature Communications. 2020;11.
doi:10.1038/s41467-020-18610-6
apa: Prehal, C., Fitzek, H., Kothleitner, G., Presser, V., Gollas, B., Freunberger,
S. A., & Abbas, Q. (2020). Persistent and reversible solid iodine electrodeposition
in nanoporous carbons. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-18610-6
chicago: Prehal, Christian, Harald Fitzek, Gerald Kothleitner, Volker Presser, Bernhard
Gollas, Stefan Alexander Freunberger, and Qamar Abbas. “Persistent and Reversible
Solid Iodine Electrodeposition in Nanoporous Carbons.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-020-18610-6.
ieee: C. Prehal et al., “Persistent and reversible solid iodine electrodeposition
in nanoporous carbons,” Nature Communications, vol. 11. Springer Nature,
2020.
ista: Prehal C, Fitzek H, Kothleitner G, Presser V, Gollas B, Freunberger SA, Abbas
Q. 2020. Persistent and reversible solid iodine electrodeposition in nanoporous
carbons. Nature Communications. 11, 4838.
mla: Prehal, Christian, et al. “Persistent and Reversible Solid Iodine Electrodeposition
in Nanoporous Carbons.” Nature Communications, vol. 11, 4838, Springer
Nature, 2020, doi:10.1038/s41467-020-18610-6.
short: C. Prehal, H. Fitzek, G. Kothleitner, V. Presser, B. Gollas, S.A. Freunberger,
Q. Abbas, Nature Communications 11 (2020).
corr_author: '1'
date_created: 2020-09-25T07:23:13Z
date_published: 2020-09-24T00:00:00Z
date_updated: 2025-06-12T06:58:51Z
day: '24'
ddc:
- '530'
department:
- _id: StFr
doi: 10.1038/s41467-020-18610-6
external_id:
isi:
- '000573756600004'
pmid:
- '32973214'
file:
- access_level: open_access
checksum: eada7bc8dd16a49390137cff882ef328
content_type: application/pdf
creator: dernst
date_created: 2020-09-28T13:16:15Z
date_updated: 2020-09-28T13:16:15Z
file_id: '8585'
file_name: 2020_NatureComm_Prehal.pdf
file_size: 1822469
relation: main_file
success: 1
file_date_updated: 2020-09-28T13:16:15Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41467-020-19720-x
scopus_import: '1'
status: public
title: Persistent and reversible solid iodine electrodeposition in nanoporous carbons
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2020'
...
---
_id: '8744'
abstract:
- lang: eng
text: Understanding the conformational sampling of translation-arrested ribosome
nascent chain complexes is key to understand co-translational folding. Up to now,
coupling of cysteine oxidation, disulfide bond formation and structure formation
in nascent chains has remained elusive. Here, we investigate the eye-lens protein
γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical
simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic
resonance and cryo-electron microscopy, we show that thiol groups of cysteine
residues undergo S-glutathionylation and S-nitrosylation and form non-native disulfide
bonds. Thus, covalent modification chemistry occurs already prior to nascent chain
release as the ribosome exit tunnel provides sufficient space even for disulfide
bond formation which can guide protein folding.
acknowledgement: 'We acknowledge help from Anja Seybert, Margot Frangakis, Diana Grewe,
Mikhail Eltsov, Utz Ermel, and Shintaro Aibara. The work was supported by Deutsche
Forschungsgemeinschaft in the CLiC graduate school. Work at the Center for Biomolecular
Magnetic Resonance (BMRZ) is supported by the German state of Hesse. The work at
BMRZ has been supported by the state of Hesse. L.S. has been supported by the DFG
graduate college: CLiC.'
article_number: '5569'
article_processing_charge: No
article_type: original
author:
- first_name: Linda
full_name: Schulte, Linda
last_name: Schulte
- first_name: Jiafei
full_name: Mao, Jiafei
last_name: Mao
- first_name: Julian
full_name: Reitz, Julian
last_name: Reitz
- first_name: Sridhar
full_name: Sreeramulu, Sridhar
last_name: Sreeramulu
- first_name: Denis
full_name: Kudlinzki, Denis
last_name: Kudlinzki
- first_name: Victor-Valentin
full_name: Hodirnau, Victor-Valentin
id: 3661B498-F248-11E8-B48F-1D18A9856A87
last_name: Hodirnau
orcid: 0000-0003-3904-947X
- first_name: Jakob
full_name: Meier-Credo, Jakob
last_name: Meier-Credo
- first_name: Krishna
full_name: Saxena, Krishna
last_name: Saxena
- first_name: Florian
full_name: Buhr, Florian
last_name: Buhr
- first_name: Julian D.
full_name: Langer, Julian D.
last_name: Langer
- first_name: Martin
full_name: Blackledge, Martin
last_name: Blackledge
- first_name: Achilleas S.
full_name: Frangakis, Achilleas S.
last_name: Frangakis
- first_name: Clemens
full_name: Glaubitz, Clemens
last_name: Glaubitz
- first_name: Harald
full_name: Schwalbe, Harald
last_name: Schwalbe
citation:
ama: Schulte L, Mao J, Reitz J, et al. Cysteine oxidation and disulfide formation
in the ribosomal exit tunnel. Nature Communications. 2020;11. doi:10.1038/s41467-020-19372-x
apa: Schulte, L., Mao, J., Reitz, J., Sreeramulu, S., Kudlinzki, D., Hodirnau, V.-V.,
… Schwalbe, H. (2020). Cysteine oxidation and disulfide formation in the ribosomal
exit tunnel. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-19372-x
chicago: Schulte, Linda, Jiafei Mao, Julian Reitz, Sridhar Sreeramulu, Denis Kudlinzki,
Victor-Valentin Hodirnau, Jakob Meier-Credo, et al. “Cysteine Oxidation and Disulfide
Formation in the Ribosomal Exit Tunnel.” Nature Communications. Springer
Nature, 2020. https://doi.org/10.1038/s41467-020-19372-x.
ieee: L. Schulte et al., “Cysteine oxidation and disulfide formation in the
ribosomal exit tunnel,” Nature Communications, vol. 11. Springer Nature,
2020.
ista: Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau V-V, Meier-Credo
J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C, Schwalbe
H. 2020. Cysteine oxidation and disulfide formation in the ribosomal exit tunnel.
Nature Communications. 11, 5569.
mla: Schulte, Linda, et al. “Cysteine Oxidation and Disulfide Formation in the Ribosomal
Exit Tunnel.” Nature Communications, vol. 11, 5569, Springer Nature, 2020,
doi:10.1038/s41467-020-19372-x.
short: L. Schulte, J. Mao, J. Reitz, S. Sreeramulu, D. Kudlinzki, V.-V. Hodirnau,
J. Meier-Credo, K. Saxena, F. Buhr, J.D. Langer, M. Blackledge, A.S. Frangakis,
C. Glaubitz, H. Schwalbe, Nature Communications 11 (2020).
date_created: 2020-11-09T07:49:36Z
date_published: 2020-11-04T00:00:00Z
date_updated: 2025-06-12T07:01:22Z
day: '04'
ddc:
- '570'
department:
- _id: EM-Fac
doi: 10.1038/s41467-020-19372-x
external_id:
isi:
- '000592028600001'
pmid:
- '33149120'
file:
- access_level: open_access
checksum: b2688f0347e69e6629bba582077278c5
content_type: application/pdf
creator: dernst
date_created: 2020-11-09T07:56:24Z
date_updated: 2020-11-09T07:56:24Z
file_id: '8745'
file_name: 2020_NatureComm_Schulte.pdf
file_size: 1670898
relation: main_file
success: 1
file_date_updated: 2020-11-09T07:56:24Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2020'
...
---
_id: '8971'
abstract:
- lang: eng
text: The actin-related protein (Arp)2/3 complex nucleates branched actin filament
networks pivotal for cell migration, endocytosis and pathogen infection. Its activation
is tightly regulated and involves complex structural rearrangements and actin
filament binding, which are yet to be understood. Here, we report a 9.0 Å resolution
structure of the actin filament Arp2/3 complex branch junction in cells using
cryo-electron tomography and subtomogram averaging. This allows us to generate
an accurate model of the active Arp2/3 complex in the branch junction and its
interaction with actin filaments. Notably, our model reveals a previously undescribed
set of interactions of the Arp2/3 complex with the mother filament, significantly
different to the previous branch junction model. Our structure also indicates
a central role for the ArpC3 subunit in stabilizing the active conformation.
acknowledged_ssus:
- _id: ScienComp
- _id: LifeSc
- _id: Bio
- _id: EM-Fac
acknowledgement: "This research was supported by the Scientific Service Units (SSUs)
of IST Austria through resources provided by Scientific Computing (SciComp), the
Life Science Facility (LSF), the BioImaging Facility (BIF), and the Electron Microscopy
Facility (EMF). We also thank Dimitry Tegunov (MPI for Biophysical Chemistry) for
helpful discussions\r\nabout the M software, and Michael Sixt (IST Austria) and
Klemens Rottner (Technical University Braunschweig, HZI Braunschweig) for critical
reading of the manuscript. We also thank Gregory Voth (University of Chicago) for
providing us the MD-derived branch junction model for comparison. The authors acknowledge
support from IST Austria and from the Austrian Science Fund (FWF): M02495 to G.D.
and Austrian Science Fund (FWF): P33367 to F.K.M.S. "
article_number: '6437'
article_processing_charge: No
article_type: original
author:
- first_name: Florian
full_name: Fäßler, Florian
id: 404F5528-F248-11E8-B48F-1D18A9856A87
last_name: Fäßler
orcid: 0000-0001-7149-769X
- first_name: Georgi A
full_name: Dimchev, Georgi A
id: 38C393BE-F248-11E8-B48F-1D18A9856A87
last_name: Dimchev
orcid: 0000-0001-8370-6161
- first_name: Victor-Valentin
full_name: Hodirnau, Victor-Valentin
id: 3661B498-F248-11E8-B48F-1D18A9856A87
last_name: Hodirnau
orcid: 0000-0003-3904-947X
- first_name: William
full_name: Wan, William
last_name: Wan
- first_name: Florian KM
full_name: Schur, Florian KM
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
citation:
ama: Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. Cryo-electron tomography
structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nature Communications. 2020;11. doi:10.1038/s41467-020-20286-x
apa: Fäßler, F., Dimchev, G. A., Hodirnau, V.-V., Wan, W., & Schur, F. K. (2020).
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights
into the branch junction. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-020-20286-x
chicago: Fäßler, Florian, Georgi A Dimchev, Victor-Valentin Hodirnau, William Wan,
and Florian KM Schur. “Cryo-Electron Tomography Structure of Arp2/3 Complex in
Cells Reveals New Insights into the Branch Junction.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-020-20286-x.
ieee: F. Fäßler, G. A. Dimchev, V.-V. Hodirnau, W. Wan, and F. K. Schur, “Cryo-electron
tomography structure of Arp2/3 complex in cells reveals new insights into the
branch junction,” Nature Communications, vol. 11. Springer Nature, 2020.
ista: Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. 2020. Cryo-electron tomography
structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nature Communications. 11, 6437.
mla: Fäßler, Florian, et al. “Cryo-Electron Tomography Structure of Arp2/3 Complex
in Cells Reveals New Insights into the Branch Junction.” Nature Communications,
vol. 11, 6437, Springer Nature, 2020, doi:10.1038/s41467-020-20286-x.
short: F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications
11 (2020).
corr_author: '1'
date_created: 2020-12-23T08:25:45Z
date_published: 2020-12-22T00:00:00Z
date_updated: 2025-04-15T07:52:12Z
day: '22'
ddc:
- '570'
department:
- _id: FlSc
- _id: EM-Fac
doi: 10.1038/s41467-020-20286-x
external_id:
isi:
- '000603078000003'
file:
- access_level: open_access
checksum: 55d43ea0061cc4027ba45e966e1db8cc
content_type: application/pdf
creator: dernst
date_created: 2020-12-28T08:16:10Z
date_updated: 2020-12-28T08:16:10Z
file_id: '8975'
file_name: 2020_NatureComm_Faessler.pdf
file_size: 3958727
relation: main_file
success: 1
file_date_updated: 2020-12-28T08:16:10Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 9B954C5C-BA93-11EA-9121-9846C619BF3A
grant_number: P33367
name: Structure and isoform diversity of the Arp2/3 complex
- _id: 2674F658-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02495
name: Protein structure and function in filopodia across scales
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/cutting-edge-technology-reveals-structures-within-cells/
scopus_import: '1'
status: public
title: Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights
into the branch junction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '9054'
abstract:
- lang: eng
text: 'The fundamental and practical importance of particle stabilization has motivated
various characterization methods for studying polymer brushes on particle surfaces.
In this work, we show how one can perform sensitive measurements of neutral polymer
coating on colloidal particles using a commercial zetameter and salt solutions.
By systematically varying the Debye length, we study the mobility of the polymer-coated
particles in an applied electric field and show that the electrophoretic mobility
of polymer-coated particles normalized by the mobility of non-coated particles
is entirely controlled by the polymer brush and independent of the native surface
charge, here controlled with pH, or the surface–ion interaction. Our result is
rationalized with a simple hydrodynamic model, allowing for the estimation of
characteristics of the polymer coating: the brush length L, and the Brinkman length
ξ, determined by its resistance to flows. We demonstrate that the Debye layer
provides a convenient and faithful probe to the characterization of polymer coatings
on particles. Because the method simply relies on a conventional zetameter, it
is widely accessible and offers a practical tool to rapidly probe neutral polymer
brushes, an asset in the development and utilization of polymer-coated colloidal
particles.'
article_processing_charge: No
article_type: original
author:
- first_name: Mena
full_name: Youssef, Mena
last_name: Youssef
- first_name: Alexandre
full_name: Morin, Alexandre
last_name: Morin
- first_name: Antoine
full_name: Aubret, Antoine
last_name: Aubret
- first_name: Stefano
full_name: Sacanna, Stefano
last_name: Sacanna
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
citation:
ama: Youssef M, Morin A, Aubret A, Sacanna S, Palacci JA. Rapid characterization
of neutral polymer brush with a conventional zetameter and a variable pinch of
salt. Soft Matter. 2020;16(17):4274-4282. doi:10.1039/c9sm01850f
apa: Youssef, M., Morin, A., Aubret, A., Sacanna, S., & Palacci, J. A. (2020).
Rapid characterization of neutral polymer brush with a conventional zetameter
and a variable pinch of salt. Soft Matter. Royal Society of Chemistry .
https://doi.org/10.1039/c9sm01850f
chicago: Youssef, Mena, Alexandre Morin, Antoine Aubret, Stefano Sacanna, and Jérémie
A Palacci. “Rapid Characterization of Neutral Polymer Brush with a Conventional
Zetameter and a Variable Pinch of Salt.” Soft Matter. Royal Society of
Chemistry , 2020. https://doi.org/10.1039/c9sm01850f.
ieee: M. Youssef, A. Morin, A. Aubret, S. Sacanna, and J. A. Palacci, “Rapid characterization
of neutral polymer brush with a conventional zetameter and a variable pinch of
salt,” Soft Matter, vol. 16, no. 17. Royal Society of Chemistry , pp. 4274–4282,
2020.
ista: Youssef M, Morin A, Aubret A, Sacanna S, Palacci JA. 2020. Rapid characterization
of neutral polymer brush with a conventional zetameter and a variable pinch of
salt. Soft Matter. 16(17), 4274–4282.
mla: Youssef, Mena, et al. “Rapid Characterization of Neutral Polymer Brush with
a Conventional Zetameter and a Variable Pinch of Salt.” Soft Matter, vol.
16, no. 17, Royal Society of Chemistry , 2020, pp. 4274–82, doi:10.1039/c9sm01850f.
short: M. Youssef, A. Morin, A. Aubret, S. Sacanna, J.A. Palacci, Soft Matter 16
(2020) 4274–4282.
date_created: 2021-02-01T13:45:11Z
date_published: 2020-05-07T00:00:00Z
date_updated: 2023-02-23T13:47:45Z
day: '07'
doi: 10.1039/c9sm01850f
extern: '1'
external_id:
pmid:
- '32307507'
intvolume: ' 16'
issue: '17'
keyword:
- General Chemistry
- Condensed Matter Physics
language:
- iso: eng
month: '05'
oa_version: None
page: 4274-4282
pmid: 1
publication: Soft Matter
publication_identifier:
eissn:
- 1744-6848
issn:
- 1744-683X
publication_status: published
publisher: 'Royal Society of Chemistry '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rapid characterization of neutral polymer brush with a conventional zetameter
and a variable pinch of salt
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 16
year: '2020'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '9067'
abstract:
- lang: eng
text: Gadolinium silicide (Gd5Si4) nanoparticles are an interesting class of materials
due to their high magnetization, low Curie temperature, low toxicity in biological
environments and their multifunctional properties. We report the magnetic and
magnetothermal properties of gadolinium silicide (Gd5Si4) nanoparticles prepared
by surfactant-assisted ball milling of arc melted bulk ingots of the compound.
Using different milling times and speeds, a wide range of crystallite sizes (13–43
nm) could be produced and a reduction in Curie temperature (TC) from 340 K to
317 K was achieved, making these nanoparticles suitable for self-controlled magnetic
hyperthermia applications. The magnetothermal effect was measured in applied AC
magnetic fields of amplitude 164–239 Oe and frequencies 163–519 kHz. All particles
showed magnetic heating with a strong dependence of the specific absorption rate
(SAR) on the average crystallite size. The highest SAR of 3.7 W g−1 was measured
for 43 nm sized nanoparticles of Gd5Si4. The high SAR and low TC, (within the
therapeutic range for magnetothermal therapy) makes the Gd5Si4 behave like self-regulating
heat switches that would be suitable for self-controlled magnetic hyperthermia
applications after biocompatibility and cytotoxicity tests.
article_processing_charge: No
article_type: original
author:
- first_name: Muhammad
full_name: Nauman, Muhammad
id: 32c21954-2022-11eb-9d5f-af9f93c24e71
last_name: Nauman
orcid: 0000-0002-2111-4846
- first_name: Muhammad Hisham
full_name: Alnasir, Muhammad Hisham
last_name: Alnasir
- first_name: Muhammad Asif
full_name: Hamayun, Muhammad Asif
last_name: Hamayun
- first_name: YiXu
full_name: Wang, YiXu
last_name: Wang
- first_name: Michael
full_name: Shatruk, Michael
last_name: Shatruk
- first_name: Sadia
full_name: Manzoor, Sadia
last_name: Manzoor
citation:
ama: Nauman M, Alnasir MH, Hamayun MA, Wang Y, Shatruk M, Manzoor S. Size-dependent
magnetic and magnetothermal properties of gadolinium silicide nanoparticles. RSC
Advances. 2020;10(47):28383-28389. doi:10.1039/d0ra05394e
apa: Nauman, M., Alnasir, M. H., Hamayun, M. A., Wang, Y., Shatruk, M., & Manzoor,
S. (2020). Size-dependent magnetic and magnetothermal properties of gadolinium
silicide nanoparticles. RSC Advances. Royal Society of Chemistry. https://doi.org/10.1039/d0ra05394e
chicago: Nauman, Muhammad, Muhammad Hisham Alnasir, Muhammad Asif Hamayun, YiXu
Wang, Michael Shatruk, and Sadia Manzoor. “Size-Dependent Magnetic and Magnetothermal
Properties of Gadolinium Silicide Nanoparticles.” RSC Advances. Royal Society
of Chemistry, 2020. https://doi.org/10.1039/d0ra05394e.
ieee: M. Nauman, M. H. Alnasir, M. A. Hamayun, Y. Wang, M. Shatruk, and S. Manzoor,
“Size-dependent magnetic and magnetothermal properties of gadolinium silicide
nanoparticles,” RSC Advances, vol. 10, no. 47. Royal Society of Chemistry,
pp. 28383–28389, 2020.
ista: Nauman M, Alnasir MH, Hamayun MA, Wang Y, Shatruk M, Manzoor S. 2020. Size-dependent
magnetic and magnetothermal properties of gadolinium silicide nanoparticles. RSC
Advances. 10(47), 28383–28389.
mla: Nauman, Muhammad, et al. “Size-Dependent Magnetic and Magnetothermal Properties
of Gadolinium Silicide Nanoparticles.” RSC Advances, vol. 10, no. 47, Royal
Society of Chemistry, 2020, pp. 28383–89, doi:10.1039/d0ra05394e.
short: M. Nauman, M.H. Alnasir, M.A. Hamayun, Y. Wang, M. Shatruk, S. Manzoor, RSC
Advances 10 (2020) 28383–28389.
date_created: 2021-02-02T15:51:23Z
date_published: 2020-07-29T00:00:00Z
date_updated: 2024-10-15T13:44:01Z
day: '29'
doi: 10.1039/d0ra05394e
extern: '1'
intvolume: ' 10'
issue: '47'
keyword:
- General Chemistry
- General Chemical Engineering
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1039/d0ra05394e
month: '07'
oa: 1
oa_version: Published Version
page: 28383-28389
publication: RSC Advances
publication_identifier:
issn:
- 2046-2069
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
status: public
title: Size-dependent magnetic and magnetothermal properties of gadolinium silicide
nanoparticles
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 10
year: '2020'
...
---
_id: '8529'
abstract:
- lang: eng
text: Practical quantum networks require low-loss and noise-resilient optical interconnects
as well as non-Gaussian resources for entanglement distillation and distributed
quantum computation. The latter could be provided by superconducting circuits
but existing solutions to interface the microwave and optical domains lack either
scalability or efficiency, and in most cases the conversion noise is not known.
In this work we utilize the unique opportunities of silicon photonics, cavity
optomechanics and superconducting circuits to demonstrate a fully integrated,
coherent transducer interfacing the microwave X and the telecom S bands with a
total (internal) bidirectional transduction efficiency of 1.2% (135%) at millikelvin
temperatures. The coupling relies solely on the radiation pressure interaction
mediated by the femtometer-scale motion of two silicon nanobeams reaching a Vπ
as low as 16 μV for sub-nanowatt pump powers. Without the associated optomechanical
gain, we achieve a total (internal) pure conversion efficiency of up to 0.019%
(1.6%), relevant for future noise-free operation on this qubit-compatible platform.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: We thank Yuan Chen for performing supplementary FEM simulations and
Andrew Higginbotham, Ralf Riedinger, Sungkun Hong, and Lorenzo Magrini for valuable
discussions. This work was supported by IST Austria, the IST nanofabrication facility
(NFF), the European Union’s Horizon 2020 research and innovation program under grant
agreement no. 732894 (FET Proactive HOT) and the European Research Council under
grant agreement no. 758053 (ERC StG QUNNECT). G.A. is the recipient of a DOC fellowship
of the Austrian Academy of Sciences at IST Austria. W.H. is the recipient of an
ISTplus postdoctoral fellowship with funding from the European Union’s Horizon 2020
research and innovation program under the Marie Sklodowska-Curie grant agreement
no. 754411. J.M.F. acknowledges support from the Austrian Science Fund (FWF) through
BeyondC (F71), a NOMIS foundation research grant, and the EU’s Horizon 2020 research
and innovation program under grant agreement no. 862644 (FET Open QUARTET).
article_number: '4460'
article_processing_charge: No
article_type: original
author:
- first_name: Georg M
full_name: Arnold, Georg M
id: 3770C838-F248-11E8-B48F-1D18A9856A87
last_name: Arnold
orcid: 0000-0003-1397-7876
- first_name: Matthias
full_name: Wulf, Matthias
id: 45598606-F248-11E8-B48F-1D18A9856A87
last_name: Wulf
orcid: 0000-0001-6613-1378
- first_name: Shabir
full_name: Barzanjeh, Shabir
id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
last_name: Barzanjeh
orcid: 0000-0003-0415-1423
- first_name: Elena
full_name: Redchenko, Elena
id: 2C21D6E8-F248-11E8-B48F-1D18A9856A87
last_name: Redchenko
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: William J
full_name: Hease, William J
id: 29705398-F248-11E8-B48F-1D18A9856A87
last_name: Hease
orcid: 0000-0001-9868-2166
- first_name: Farid
full_name: Hassani, Farid
id: 2AED110C-F248-11E8-B48F-1D18A9856A87
last_name: Hassani
orcid: 0000-0001-6937-5773
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Arnold GM, Wulf M, Barzanjeh S, et al. Converting microwave and telecom photons
with a silicon photonic nanomechanical interface. Nature Communications.
2020;11. doi:10.1038/s41467-020-18269-z
apa: Arnold, G. M., Wulf, M., Barzanjeh, S., Redchenko, E., Rueda Sanchez, A. R.,
Hease, W. J., … Fink, J. M. (2020). Converting microwave and telecom photons with
a silicon photonic nanomechanical interface. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-020-18269-z
chicago: Arnold, Georg M, Matthias Wulf, Shabir Barzanjeh, Elena Redchenko, Alfredo
R Rueda Sanchez, William J Hease, Farid Hassani, and Johannes M Fink. “Converting
Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.”
Nature Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-020-18269-z.
ieee: G. M. Arnold et al., “Converting microwave and telecom photons with
a silicon photonic nanomechanical interface,” Nature Communications, vol.
11. Springer Nature, 2020.
ista: Arnold GM, Wulf M, Barzanjeh S, Redchenko E, Rueda Sanchez AR, Hease WJ, Hassani
F, Fink JM. 2020. Converting microwave and telecom photons with a silicon photonic
nanomechanical interface. Nature Communications. 11, 4460.
mla: Arnold, Georg M., et al. “Converting Microwave and Telecom Photons with a Silicon
Photonic Nanomechanical Interface.” Nature Communications, vol. 11, 4460,
Springer Nature, 2020, doi:10.1038/s41467-020-18269-z.
short: G.M. Arnold, M. Wulf, S. Barzanjeh, E. Redchenko, A.R. Rueda Sanchez, W.J.
Hease, F. Hassani, J.M. Fink, Nature Communications 11 (2020).
corr_author: '1'
date_created: 2020-09-18T10:56:20Z
date_published: 2020-09-08T00:00:00Z
date_updated: 2026-06-28T22:30:25Z
day: '08'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.1038/s41467-020-18269-z
ec_funded: 1
external_id:
isi:
- '000577280200001'
pmid:
- '32901014'
file:
- access_level: open_access
checksum: 88f92544889eb18bb38e25629a422a86
content_type: application/pdf
creator: dernst
date_created: 2020-09-18T13:02:37Z
date_updated: 2020-09-18T13:02:37Z
file_id: '8530'
file_name: 2020_NatureComm_Arnold.pdf
file_size: 1002818
relation: main_file
success: 1
file_date_updated: 2020-09-18T13:02:37Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 257EB838-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '732894'
name: Hybrid Optomechanical Technologies
- _id: 26336814-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '758053'
name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '862644'
name: Quantum readout techniques and technologies
- _id: 2671EB66-B435-11E9-9278-68D0E5697425
name: Coherent on-chip conversion of superconducting qubit signals from microwaves
to optical frequencies
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41467-020-18912-9
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/how-to-transport-microwave-quantum-information-via-optical-fiber/
record:
- id: '13056'
relation: research_data
status: public
- id: '18871'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Converting microwave and telecom photons with a silicon photonic nanomechanical
interface
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2020'
...
---
_id: '13370'
abstract:
- lang: eng
text: Efficient isomerization of photochromic molecules often requires conformational
freedom and is typically not available under solvent-free conditions. Here, we
report a general methodology allowing for reversible switching of such molecules
on the surfaces of solid materials. Our method is based on dispersing photochromic
compounds within polysilsesquioxane nanowire networks (PNNs), which can be fabricated
as transparent, highly porous, micrometer-thick layers on various substrates.
We found that azobenzene switching within the PNNs proceeded unusually fast compared
with the same molecules in liquid solvents. Efficient isomerization of another
photochromic system, spiropyran, from a colorless to a colored form was used to
create reversible images in PNN-coated glass. The coloration reaction could be
induced with sunlight and is of interest for developing “smart” windows.
article_processing_charge: No
article_type: original
author:
- first_name: Zonglin
full_name: Chu, Zonglin
last_name: Chu
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Chu Z, Klajn R. Polysilsesquioxane nanowire networks as an “Artificial Solvent”
for reversible operation of photochromic molecules. Nano Letters. 2019;19(10):7106-7111.
doi:10.1021/acs.nanolett.9b02642
apa: Chu, Z., & Klajn, R. (2019). Polysilsesquioxane nanowire networks as an
“Artificial Solvent” for reversible operation of photochromic molecules. Nano
Letters. American Chemical Society. https://doi.org/10.1021/acs.nanolett.9b02642
chicago: Chu, Zonglin, and Rafal Klajn. “Polysilsesquioxane Nanowire Networks as
an ‘Artificial Solvent’ for Reversible Operation of Photochromic Molecules.” Nano
Letters. American Chemical Society, 2019. https://doi.org/10.1021/acs.nanolett.9b02642.
ieee: Z. Chu and R. Klajn, “Polysilsesquioxane nanowire networks as an ‘Artificial
Solvent’ for reversible operation of photochromic molecules,” Nano Letters,
vol. 19, no. 10. American Chemical Society, pp. 7106–7111, 2019.
ista: Chu Z, Klajn R. 2019. Polysilsesquioxane nanowire networks as an “Artificial
Solvent” for reversible operation of photochromic molecules. Nano Letters. 19(10),
7106–7111.
mla: Chu, Zonglin, and Rafal Klajn. “Polysilsesquioxane Nanowire Networks as an
‘Artificial Solvent’ for Reversible Operation of Photochromic Molecules.” Nano
Letters, vol. 19, no. 10, American Chemical Society, 2019, pp. 7106–11, doi:10.1021/acs.nanolett.9b02642.
short: Z. Chu, R. Klajn, Nano Letters 19 (2019) 7106–7111.
date_created: 2023-08-01T09:38:23Z
date_published: 2019-09-20T00:00:00Z
date_updated: 2024-10-14T12:13:57Z
day: '20'
doi: 10.1021/acs.nanolett.9b02642
extern: '1'
external_id:
pmid:
- '31539469'
intvolume: ' 19'
issue: '10'
keyword:
- Mechanical Engineering
- Condensed Matter Physics
- General Materials Science
- General Chemistry
- Bioengineering
language:
- iso: eng
month: '09'
oa_version: None
page: 7106-7111
pmid: 1
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
issn:
- 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polysilsesquioxane nanowire networks as an “Artificial Solvent” for reversible
operation of photochromic molecules
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2019'
...
---
_id: '13371'
abstract:
- lang: eng
text: Diamondoid nanoporous crystals represent a synthetically challenging class
of materials that typically have been obtained from tetrahedral building blocks.
In this issue of Chem, Stoddart and coworkers demonstrate that it is possible
to generate diamondoid frameworks from a hexacationic building block lacking a
tetrahedral symmetry. These results highlight the great potential of self-assembly
for rapidly transforming small molecules into structurally complex functional
materials.
article_processing_charge: No
article_type: original
author:
- first_name: Michał J.
full_name: Białek, Michał J.
last_name: Białek
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Białek MJ, Klajn R. Diamond grows up. Chem. 2019;5(9):2283-2285. doi:10.1016/j.chempr.2019.08.012
apa: Białek, M. J., & Klajn, R. (2019). Diamond grows up. Chem. Elsevier.
https://doi.org/10.1016/j.chempr.2019.08.012
chicago: Białek, Michał J., and Rafal Klajn. “Diamond Grows Up.” Chem. Elsevier,
2019. https://doi.org/10.1016/j.chempr.2019.08.012.
ieee: M. J. Białek and R. Klajn, “Diamond grows up,” Chem, vol. 5, no. 9.
Elsevier, pp. 2283–2285, 2019.
ista: Białek MJ, Klajn R. 2019. Diamond grows up. Chem. 5(9), 2283–2285.
mla: Białek, Michał J., and Rafal Klajn. “Diamond Grows Up.” Chem, vol. 5,
no. 9, Elsevier, 2019, pp. 2283–85, doi:10.1016/j.chempr.2019.08.012.
short: M.J. Białek, R. Klajn, Chem 5 (2019) 2283–2285.
date_created: 2023-08-01T09:38:38Z
date_published: 2019-09-12T00:00:00Z
date_updated: 2024-10-14T12:14:05Z
day: '12'
doi: 10.1016/j.chempr.2019.08.012
extern: '1'
intvolume: ' 5'
issue: '9'
keyword:
- Materials Chemistry
- Biochemistry (medical)
- General Chemical Engineering
- Environmental Chemistry
- Biochemistry
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.chempr.2019.08.012
month: '09'
oa: 1
oa_version: Published Version
page: 2283-2285
publication: Chem
publication_identifier:
eissn:
- 2451-9294
issn:
- 2451-9308
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Diamond grows up
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2019'
...
---
_id: '13372'
abstract:
- lang: eng
text: 'The capacity to respond or adapt to environmental changes is an intrinsic
property of living systems that comprise highly-connected subcomponents communicating
through chemical networks. The development of responsive synthetic systems is
a relatively new research area that covers different disciplines, among which
nanochemistry brings conceptually new demonstrations. Especially attractive are
ligand-protected gold nanoparticles, which have been extensively used over the
last decade as building blocks in constructing superlattices or dynamic aggregates,
under the effect of an applied stimulus. To reflect the importance of surface
chemistry and nanoparticle core composition in the dynamic self-assembly of nanoparticles,
we provide here an overview of various available stimuli, as tools for synthetic
chemists to exploit. Along with this task, the review starts with the use of chemical
stimuli such as solvent, pH, gases, metal ions or biomolecules. It then focuses
on physical stimuli: temperature, magnetic and electric fields, as well as light.
To reflect on the increasing complexity of current architectures, we discuss systems
that are responsive to more than one stimulus, to finally encourage further research
by proposing future challenges.'
article_processing_charge: No
article_type: original
author:
- first_name: Marek
full_name: Grzelczak, Marek
last_name: Grzelczak
- first_name: Luis M.
full_name: Liz-Marzán, Luis M.
last_name: Liz-Marzán
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Grzelczak M, Liz-Marzán LM, Klajn R. Stimuli-responsive self-assembly of nanoparticles.
Chemical Society Reviews. 2019;48(5):1342-1361. doi:10.1039/c8cs00787j
apa: Grzelczak, M., Liz-Marzán, L. M., & Klajn, R. (2019). Stimuli-responsive
self-assembly of nanoparticles. Chemical Society Reviews. Royal Society
of Chemistry. https://doi.org/10.1039/c8cs00787j
chicago: Grzelczak, Marek, Luis M. Liz-Marzán, and Rafal Klajn. “Stimuli-Responsive
Self-Assembly of Nanoparticles.” Chemical Society Reviews. Royal Society
of Chemistry, 2019. https://doi.org/10.1039/c8cs00787j.
ieee: M. Grzelczak, L. M. Liz-Marzán, and R. Klajn, “Stimuli-responsive self-assembly
of nanoparticles,” Chemical Society Reviews, vol. 48, no. 5. Royal Society
of Chemistry, pp. 1342–1361, 2019.
ista: Grzelczak M, Liz-Marzán LM, Klajn R. 2019. Stimuli-responsive self-assembly
of nanoparticles. Chemical Society Reviews. 48(5), 1342–1361.
mla: Grzelczak, Marek, et al. “Stimuli-Responsive Self-Assembly of Nanoparticles.”
Chemical Society Reviews, vol. 48, no. 5, Royal Society of Chemistry, 2019,
pp. 1342–61, doi:10.1039/c8cs00787j.
short: M. Grzelczak, L.M. Liz-Marzán, R. Klajn, Chemical Society Reviews 48 (2019)
1342–1361.
date_created: 2023-08-01T09:38:52Z
date_published: 2019-01-28T00:00:00Z
date_updated: 2024-10-14T12:14:14Z
day: '28'
doi: 10.1039/c8cs00787j
extern: '1'
external_id:
pmid:
- '30688963'
intvolume: ' 48'
issue: '5'
keyword:
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1039/C8CS00787J
month: '01'
oa: 1
oa_version: Published Version
page: 1342-1361
pmid: 1
publication: Chemical Society Reviews
publication_identifier:
eissn:
- 1460-4744
issn:
- 0306-0012
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: Stimuli-responsive self-assembly of nanoparticles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2019'
...
---
_id: '13373'
abstract:
- lang: eng
text: The reversible photoisomerization of azobenzene has been utilized to construct
a plethora of systems in which optical, electronic, catalytic, and other properties
can be controlled by light. However, owing to azobenzene’s hydrophobic nature,
most of these examples have been realized only in organic solvents, and systems
operating in water are relatively scarce. Here, we show that by coadsorbing the
inherently hydrophobic azobenzenes with water-solubilizing ligands on the same
nanoparticulate platforms, it is possible to render them essentially water-soluble.
To this end, we developed a modified nanoparticle functionalization procedure
allowing us to precisely fine-tune the amount of azobenzene on the functionalized
nanoparticles. Molecular dynamics simulations helped us to identify two distinct
supramolecular architectures (depending on the length of the background ligand)
on these nanoparticles, which can explain their excellent aqueous solubilities.
Azobenzenes adsorbed on these water-soluble nanoparticles exhibit highly reversible
photoisomerization upon exposure to UV and visible light. Importantly, the mixed-monolayer
approach allowed us to systematically investigate how the background ligand affects
the switching properties of azobenzene. We found that the nature of the background
ligand has a profound effect on the kinetics of azobenzene switching. For example,
a hydroxy-terminated background ligand is capable of accelerating the back-isomerization
reaction by more than 6000-fold. These results pave the way toward the development
of novel light-responsive nanomaterials operating in aqueous media and, in the
long run, in biological environments.
article_processing_charge: No
article_type: original
author:
- first_name: Zonglin
full_name: Chu, Zonglin
last_name: Chu
- first_name: Yanxiao
full_name: Han, Yanxiao
last_name: Han
- first_name: Tong
full_name: Bian, Tong
last_name: Bian
- first_name: Soumen
full_name: De, Soumen
last_name: De
- first_name: Petr
full_name: Král, Petr
last_name: Král
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Chu Z, Han Y, Bian T, De S, Král P, Klajn R. Supramolecular control of azobenzene
switching on nanoparticles. Journal of the American Chemical Society. 2019;141(5):1949-1960.
doi:10.1021/jacs.8b09638
apa: Chu, Z., Han, Y., Bian, T., De, S., Král, P., & Klajn, R. (2019). Supramolecular
control of azobenzene switching on nanoparticles. Journal of the American Chemical
Society. American Chemical Society. https://doi.org/10.1021/jacs.8b09638
chicago: Chu, Zonglin, Yanxiao Han, Tong Bian, Soumen De, Petr Král, and Rafal Klajn.
“Supramolecular Control of Azobenzene Switching on Nanoparticles.” Journal
of the American Chemical Society. American Chemical Society, 2019. https://doi.org/10.1021/jacs.8b09638.
ieee: Z. Chu, Y. Han, T. Bian, S. De, P. Král, and R. Klajn, “Supramolecular control
of azobenzene switching on nanoparticles,” Journal of the American Chemical
Society, vol. 141, no. 5. American Chemical Society, pp. 1949–1960, 2019.
ista: Chu Z, Han Y, Bian T, De S, Král P, Klajn R. 2019. Supramolecular control
of azobenzene switching on nanoparticles. Journal of the American Chemical Society.
141(5), 1949–1960.
mla: Chu, Zonglin, et al. “Supramolecular Control of Azobenzene Switching on Nanoparticles.”
Journal of the American Chemical Society, vol. 141, no. 5, American Chemical
Society, 2019, pp. 1949–60, doi:10.1021/jacs.8b09638.
short: Z. Chu, Y. Han, T. Bian, S. De, P. Král, R. Klajn, Journal of the American
Chemical Society 141 (2019) 1949–1960.
date_created: 2023-08-01T09:39:19Z
date_published: 2019-02-06T00:00:00Z
date_updated: 2024-10-14T12:14:23Z
day: '06'
doi: 10.1021/jacs.8b09638
extern: '1'
external_id:
pmid:
- '30595017'
intvolume: ' 141'
issue: '5'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
month: '02'
oa_version: Published Version
page: 1949-1960
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Supramolecular control of azobenzene switching on nanoparticles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 141
year: '2019'
...