[{"publication":"Nature Communications","year":"2019","volume":10,"title":"Activity-controlled annealing of colloidal monolayers","external_id":{"arxiv":["1909.07382"],"pmid":["31358762"]},"article_type":"original","publication_identifier":{"issn":["2041-1723"]},"article_processing_charge":"No","date_created":"2021-02-02T13:43:36Z","file_date_updated":"2021-02-02T13:47:21Z","_id":"9060","author":[{"full_name":"Ramananarivo, Sophie","last_name":"Ramananarivo","first_name":"Sophie"},{"full_name":"Ducrot, Etienne","last_name":"Ducrot","first_name":"Etienne"},{"full_name":"Palacci, Jérémie A","last_name":"Palacci","id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","orcid":"0000-0002-7253-9465","first_name":"Jérémie A"}],"keyword":["General Biochemistry","Genetics and Molecular Biology","General Physics and Astronomy","General Chemistry"],"citation":{"apa":"Ramananarivo, S., Ducrot, E., & Palacci, J. A. (2019). Activity-controlled annealing of colloidal monolayers. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-019-11362-y","short":"S. Ramananarivo, E. Ducrot, J.A. Palacci, Nature Communications 10 (2019).","chicago":"Ramananarivo, Sophie, Etienne Ducrot, and Jérémie A Palacci. “Activity-Controlled Annealing of Colloidal Monolayers.” Nature Communications. Springer Nature, 2019. https://doi.org/10.1038/s41467-019-11362-y.","ieee":"S. Ramananarivo, E. Ducrot, and J. A. Palacci, “Activity-controlled annealing of colloidal monolayers,” Nature Communications, vol. 10, no. 1. Springer Nature, 2019.","ista":"Ramananarivo S, Ducrot E, Palacci JA. 2019. Activity-controlled annealing of colloidal monolayers. Nature Communications. 10(1), 3380.","mla":"Ramananarivo, Sophie, et al. “Activity-Controlled Annealing of Colloidal Monolayers.” Nature Communications, vol. 10, no. 1, 3380, Springer Nature, 2019, doi:10.1038/s41467-019-11362-y.","ama":"Ramananarivo S, Ducrot E, Palacci JA. Activity-controlled annealing of colloidal monolayers. Nature Communications. 2019;10(1). doi:10.1038/s41467-019-11362-y"},"quality_controlled":"1","scopus_import":"1","article_number":"3380","has_accepted_license":"1","type":"journal_article","publisher":"Springer Nature","intvolume":" 10","status":"public","date_published":"2019-07-29T00:00:00Z","extern":"1","ddc":["530"],"publication_status":"published","abstract":[{"text":"Molecular motors are essential to the living, generating fluctuations that boost transport and assist assembly. Active colloids, that consume energy to move, hold similar potential for man-made materials controlled by forces generated from within. Yet, their use as a powerhouse in materials science lacks. Here we show a massive acceleration of the annealing of a monolayer of passive beads by moderate addition of self-propelled microparticles. We rationalize our observations with a model of collisions that drive active fluctuations and activate the annealing. The experiment is quantitatively compared with Brownian dynamic simulations that further unveil a dynamical transition in the mechanism of annealing. Active dopants travel uniformly in the system or co-localize at the grain boundaries as a result of the persistence of their motion. Our findings uncover the potential of internal activity to control materials and lay the groundwork for the rise of materials science beyond equilibrium.","lang":"eng"}],"user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","doi":"10.1038/s41467-019-11362-y","pmid":1,"month":"07","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"language":[{"iso":"eng"}],"oa":1,"arxiv":1,"oa_version":"Published Version","date_updated":"2023-02-23T13:47:59Z","issue":"1","file":[{"file_id":"9061","date_created":"2021-02-02T13:47:21Z","checksum":"70c6e5d6fbea0932b0669505ab6633ec","file_size":2820337,"file_name":"2019_NatureComm_Ramananarivo.pdf","success":1,"date_updated":"2021-02-02T13:47:21Z","access_level":"open_access","creator":"cziletti","relation":"main_file","content_type":"application/pdf"}],"license":"https://creativecommons.org/licenses/by/4.0/","day":"29"},{"language":[{"iso":"eng"}],"oa":1,"oa_version":"Published Version","date_updated":"2024-10-14T12:14:34Z","day":"13","status":"public","date_published":"2018-02-13T00:00:00Z","publication_status":"published","abstract":[{"text":"Confining molecules to volumes only slightly larger than the molecules themselves can profoundly alter their properties. Molecular switches—entities that can be toggled between two or more forms upon exposure to an external stimulus—often require conformational freedom to isomerize. Therefore, placing these switches in confined spaces can render them non-operational. To preserve the switchability of these species under confinement, we work with a water-soluble coordination cage that is flexible enough to adapt its shape to the conformation of the encapsulated guest. We show that owing to its flexibility, the cage is not only capable of accommodating—and solubilizing in water—several light-responsive spiropyran-based molecular switches, but, more importantly, it also provides an environment suitable for the efficient, reversible photoisomerization of the bound guests. Our findings pave the way towards studying various molecular switching processes in confined environments.","lang":"eng"}],"extern":"1","pmid":1,"doi":"10.1038/s41467-017-02715-6","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-017-02715-6"}],"month":"02","author":[{"first_name":"Dipak","last_name":"Samanta","full_name":"Samanta, Dipak"},{"first_name":"Daria","last_name":"Galaktionova","full_name":"Galaktionova, Daria"},{"full_name":"Gemen, Julius","first_name":"Julius","last_name":"Gemen"},{"first_name":"Linda J. W.","last_name":"Shimon","full_name":"Shimon, Linda J. W."},{"last_name":"Diskin-Posner","first_name":"Yael","full_name":"Diskin-Posner, Yael"},{"first_name":"Liat","last_name":"Avram","full_name":"Avram, Liat"},{"full_name":"Král, Petr","last_name":"Král","first_name":"Petr"},{"last_name":"Klajn","id":"8e84690e-1e48-11ed-a02b-a1e6fb8bb53b","first_name":"Rafal","full_name":"Klajn, Rafal"}],"_id":"13374","citation":{"ista":"Samanta D, Galaktionova D, Gemen J, Shimon LJW, Diskin-Posner Y, Avram L, Král P, Klajn R. 2018. Reversible chromism of spiropyran in the cavity of a flexible coordination cage. Nature Communications. 9, 641.","ieee":"D. Samanta et al., “Reversible chromism of spiropyran in the cavity of a flexible coordination cage,” Nature Communications, vol. 9. Springer Nature, 2018.","mla":"Samanta, Dipak, et al. “Reversible Chromism of Spiropyran in the Cavity of a Flexible Coordination Cage.” Nature Communications, vol. 9, 641, Springer Nature, 2018, doi:10.1038/s41467-017-02715-6.","ama":"Samanta D, Galaktionova D, Gemen J, et al. Reversible chromism of spiropyran in the cavity of a flexible coordination cage. Nature Communications. 2018;9. doi:10.1038/s41467-017-02715-6","short":"D. Samanta, D. Galaktionova, J. Gemen, L.J.W. Shimon, Y. Diskin-Posner, L. Avram, P. Král, R. Klajn, Nature Communications 9 (2018).","apa":"Samanta, D., Galaktionova, D., Gemen, J., Shimon, L. J. W., Diskin-Posner, Y., Avram, L., … Klajn, R. (2018). Reversible chromism of spiropyran in the cavity of a flexible coordination cage. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-017-02715-6","chicago":"Samanta, Dipak, Daria Galaktionova, Julius Gemen, Linda J. W. Shimon, Yael Diskin-Posner, Liat Avram, Petr Král, and Rafal Klajn. “Reversible Chromism of Spiropyran in the Cavity of a Flexible Coordination Cage.” Nature Communications. Springer Nature, 2018. https://doi.org/10.1038/s41467-017-02715-6."},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"quality_controlled":"1","scopus_import":"1","article_number":"641","type":"journal_article","publisher":"Springer Nature","intvolume":" 9","year":"2018","publication":"Nature Communications","title":"Reversible chromism of spiropyran in the cavity of a flexible coordination cage","article_type":"original","external_id":{"pmid":["29440687"]},"volume":9,"related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/s41467-018-03701-2"}]},"publication_identifier":{"eissn":["2041-1723"]},"date_created":"2023-08-01T09:39:32Z","article_processing_charge":"No"},{"day":"01","date_updated":"2023-08-22T07:42:07Z","oa_version":"Published Version","issue":"3","oa":1,"language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1103/PhysRevX.8.031060"}],"month":"07","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1103/physrevx.8.031060","extern":"1","abstract":[{"text":"Molecular chirality plays an essential role in most biochemical processes. The observation and quantification of chirality-sensitive signals, however, remains extremely challenging, especially on ultrafast timescales and in dilute media. Here, we describe the experimental realization of an all-optical and ultrafast scheme for detecting chiral dynamics in molecules. This technique is based on high-harmonic generation by a combination of two-color counterrotating femtosecond laser pulses with polarization states tunable from linear to circular. We demonstrate two different implementations of chiral-sensitive high-harmonic spectroscopy on an ensemble of randomly oriented methyloxirane molecules in the gas phase. Using two elliptically polarized fields, we observe that the ellipticities maximizing the harmonic signal reach up to \r\n4.4\r\n±\r\n0.2\r\n%\r\n (at 17.6 eV). Using two circularly polarized fields, we observe circular dichroisms ranging up to \r\n13\r\n±\r\n6\r\n%\r\n (28.3–33.1 eV). Our theoretical analysis confirms that the observed chiral response originates from subfemtosecond electron dynamics driven by the magnetic component of the driving laser field. This assignment is supported by the experimental observation of a strong intensity dependence of the chiral effects and its agreement with theory. We moreover report and explain a pronounced variation of the signal strength and dichroism with the driving-field ellipticities and harmonic orders. Finally, we demonstrate the sensitivity of the experimental observables to the shape of the electron hole. This technique for chiral discrimination will yield femtosecond temporal resolution when integrated in a pump-probe scheme and subfemtosecond resolution on chiral charge migration in a self-probing scheme.","lang":"eng"}],"publication_status":"published","status":"public","date_published":"2018-07-01T00:00:00Z","publisher":"American Physical Society","intvolume":" 8","type":"journal_article","keyword":["General Physics and Astronomy"],"citation":{"ieee":"D. R. Baykusheva and H. J. Wörner, “Chiral discrimination through bielliptical high-harmonic spectroscopy,” Physical Review X, vol. 8, no. 3. American Physical Society, 2018.","mla":"Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Chiral Discrimination through Bielliptical High-Harmonic Spectroscopy.” Physical Review X, vol. 8, no. 3, 031060, American Physical Society, 2018, doi:10.1103/physrevx.8.031060.","ista":"Baykusheva DR, Wörner HJ. 2018. Chiral discrimination through bielliptical high-harmonic spectroscopy. Physical Review X. 8(3), 031060.","ama":"Baykusheva DR, Wörner HJ. Chiral discrimination through bielliptical high-harmonic spectroscopy. Physical Review X. 2018;8(3). doi:10.1103/physrevx.8.031060","apa":"Baykusheva, D. R., & Wörner, H. J. (2018). Chiral discrimination through bielliptical high-harmonic spectroscopy. Physical Review X. American Physical Society. https://doi.org/10.1103/physrevx.8.031060","short":"D.R. Baykusheva, H.J. Wörner, Physical Review X 8 (2018).","chicago":"Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Chiral Discrimination through Bielliptical High-Harmonic Spectroscopy.” Physical Review X. American Physical Society, 2018. https://doi.org/10.1103/physrevx.8.031060."},"quality_controlled":"1","scopus_import":"1","article_number":"031060","_id":"14003","author":[{"first_name":"Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","full_name":"Baykusheva, Denitsa Rangelova"},{"full_name":"Wörner, Hans Jakob","last_name":"Wörner","first_name":"Hans Jakob"}],"publication_identifier":{"eissn":["2160-3308"]},"article_processing_charge":"No","date_created":"2023-08-10T06:34:48Z","publication":"Physical Review X","year":"2018","volume":8,"article_type":"original","title":"Chiral discrimination through bielliptical high-harmonic spectroscopy"},{"publisher":"Springer Nature","intvolume":" 9","type":"journal_article","citation":{"ama":"Bräuning B, Bertosin E, Praetorius FM, et al. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Nature Communications. 2018;9. doi:10.1038/s41467-018-04139-2","ista":"Bräuning B, Bertosin E, Praetorius FM, Ihling C, Schatt A, Adler A, Richter K, Sinz A, Dietz H, Groll M. 2018. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Nature Communications. 9, 1806.","mla":"Bräuning, Bastian, et al. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” Nature Communications, vol. 9, 1806, Springer Nature, 2018, doi:10.1038/s41467-018-04139-2.","ieee":"B. Bräuning et al., “Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB,” Nature Communications, vol. 9. Springer Nature, 2018.","chicago":"Bräuning, Bastian, Eva Bertosin, Florian M Praetorius, Christian Ihling, Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, and Michael Groll. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” Nature Communications. Springer Nature, 2018. https://doi.org/10.1038/s41467-018-04139-2.","short":"B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).","apa":"Bräuning, B., Bertosin, E., Praetorius, F. M., Ihling, C., Schatt, A., Adler, A., … Groll, M. (2018). Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-018-04139-2"},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"quality_controlled":"1","article_number":"1806","scopus_import":"1","author":[{"full_name":"Bräuning, Bastian","last_name":"Bräuning","first_name":"Bastian"},{"first_name":"Eva","last_name":"Bertosin","full_name":"Bertosin, Eva"},{"last_name":"Praetorius","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","first_name":"Florian M","full_name":"Praetorius, Florian M"},{"full_name":"Ihling, Christian","last_name":"Ihling","first_name":"Christian"},{"last_name":"Schatt","first_name":"Alexandra","full_name":"Schatt, Alexandra"},{"full_name":"Adler, Agnes","first_name":"Agnes","last_name":"Adler"},{"last_name":"Richter","first_name":"Klaus","full_name":"Richter, Klaus"},{"first_name":"Andrea","last_name":"Sinz","full_name":"Sinz, Andrea"},{"first_name":"Hendrik","last_name":"Dietz","full_name":"Dietz, Hendrik"},{"full_name":"Groll, Michael","first_name":"Michael","last_name":"Groll"}],"_id":"14284","publication_identifier":{"issn":["2041-1723"]},"date_created":"2023-09-06T12:07:33Z","article_processing_charge":"No","year":"2018","publication":"Nature Communications","external_id":{"pmid":["29728606"]},"article_type":"original","title":"Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB","volume":9,"day":"04","date_updated":"2023-11-07T11:46:12Z","oa_version":"Published Version","language":[{"iso":"eng"}],"oa":1,"main_file_link":[{"url":"https://doi.org/10.1038/s41467-018-04139-2","open_access":"1"}],"month":"05","pmid":1,"doi":"10.1038/s41467-018-04139-2","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. YaxAB was shown to be cytotoxic and likely involved in pathogenesis, though the molecular basis for its two-component lytic mechanism remains elusive. Here, we present crystal structures of YaxA and YaxB, together with a cryo-electron microscopy map of the YaxAB complex. Our structures reveal a pore predominantly composed of decamers of YaxA–YaxB heterodimers. Both subunits bear membrane-active moieties, but only YaxA is capable of binding to membranes by itself. YaxB can subsequently be recruited to membrane-associated YaxA and induced to present its lytic transmembrane helices. Pore formation can progress by further oligomerization of YaxA–YaxB dimers. Our results allow for a comparison between pore assemblies belonging to the wider ClyA-like family of α-PFTs, highlighting diverse pore architectures.","lang":"eng"}],"publication_status":"published","extern":"1","status":"public","date_published":"2018-05-04T00:00:00Z"},{"status":"public","date_published":"2018-12-07T00:00:00Z","publication_status":"published","abstract":[{"text":"In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry (eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced “spectral-timing-polarimetry” techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process. ","lang":"eng"}],"extern":"1","doi":"10.1007/s11433-018-9297-0","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.1812.04022"}],"month":"12","oa":1,"language":[{"iso":"eng"}],"arxiv":1,"issue":"2","oa_version":"Preprint","date_updated":"2024-04-05T07:12:09Z","day":"07","year":"2018","publication":"Science China Physics, Mechanics & Astronomy","article_type":"original","title":"Accretion in strong field gravity with eXTP","external_id":{"arxiv":["1812.04022"]},"volume":62,"publication_identifier":{"issn":["1674-7348"],"eissn":["1869-1927"]},"date_created":"2024-03-26T10:37:41Z","article_processing_charge":"No","author":[{"last_name":"Rosa","first_name":"Alessandra De","full_name":"Rosa, Alessandra De"},{"first_name":"Phil","last_name":"Uttley","full_name":"Uttley, Phil"},{"full_name":"Gou, LiJun","first_name":"LiJun","last_name":"Gou"},{"full_name":"Liu, Yuan","first_name":"Yuan","last_name":"Liu"},{"full_name":"Bambi, Cosimo","first_name":"Cosimo","last_name":"Bambi"},{"first_name":"Didier","last_name":"Barret","full_name":"Barret, Didier"},{"full_name":"Belloni, Tomaso","last_name":"Belloni","first_name":"Tomaso"},{"full_name":"Berti, Emanuele","last_name":"Berti","first_name":"Emanuele"},{"first_name":"Stefano","last_name":"Bianchi","full_name":"Bianchi, Stefano"},{"full_name":"Caiazzo, Ilaria","first_name":"Ilaria","orcid":"0000-0002-4770-5388","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","last_name":"Caiazzo"},{"full_name":"Casella, Piergiorgio","first_name":"Piergiorgio","last_name":"Casella"},{"full_name":"Feroci, Marco","last_name":"Feroci","first_name":"Marco"},{"last_name":"Ferrari","first_name":"Valeria","full_name":"Ferrari, Valeria"},{"full_name":"Gualtieri, Leonardo","last_name":"Gualtieri","first_name":"Leonardo"},{"full_name":"Heyl, Jeremy","first_name":"Jeremy","last_name":"Heyl"},{"full_name":"Ingram, Adam","last_name":"Ingram","first_name":"Adam"},{"first_name":"Vladimir","last_name":"Karas","full_name":"Karas, Vladimir"},{"full_name":"Lu, FangJun","last_name":"Lu","first_name":"FangJun"},{"full_name":"Luo, Bin","first_name":"Bin","last_name":"Luo"},{"first_name":"Giorgio","last_name":"Matt","full_name":"Matt, Giorgio"},{"full_name":"Motta, Sara","last_name":"Motta","first_name":"Sara"},{"last_name":"Neilsen","first_name":"Joseph","full_name":"Neilsen, Joseph"},{"full_name":"Pani, Paolo","last_name":"Pani","first_name":"Paolo"},{"full_name":"Santangelo, Andrea","first_name":"Andrea","last_name":"Santangelo"},{"last_name":"Shu","first_name":"XinWen","full_name":"Shu, XinWen"},{"full_name":"Wang, JunFeng","last_name":"Wang","first_name":"JunFeng"},{"last_name":"Wang","first_name":"Jian-Min","full_name":"Wang, Jian-Min"},{"last_name":"Xue","first_name":"YongQuan","full_name":"Xue, YongQuan"},{"first_name":"YuPeng","last_name":"Xu","full_name":"Xu, YuPeng"},{"last_name":"Yuan","first_name":"WeiMin","full_name":"Yuan, WeiMin"},{"last_name":"Yuan","first_name":"YeFei","full_name":"Yuan, YeFei"},{"last_name":"Zhang","first_name":"Shuang-Nan","full_name":"Zhang, Shuang-Nan"},{"first_name":"Shu","last_name":"Zhang","full_name":"Zhang, Shu"},{"first_name":"Ivan","last_name":"Agudo","full_name":"Agudo, Ivan"},{"first_name":"Lorenzo","last_name":"Amati","full_name":"Amati, Lorenzo"},{"last_name":"Andersson","first_name":"Nils","full_name":"Andersson, Nils"},{"first_name":"Cristina","last_name":"Baglio","full_name":"Baglio, Cristina"},{"full_name":"Bakala, Pavel","last_name":"Bakala","first_name":"Pavel"},{"first_name":"Altan","last_name":"Baykal","full_name":"Baykal, Altan"},{"full_name":"Bhattacharyya, Sudip","first_name":"Sudip","last_name":"Bhattacharyya"},{"full_name":"Bombaci, Ignazio","last_name":"Bombaci","first_name":"Ignazio"},{"last_name":"Bucciantini","first_name":"Niccoló","full_name":"Bucciantini, Niccoló"},{"first_name":"Fiamma","last_name":"Capitanio","full_name":"Capitanio, Fiamma"},{"last_name":"Ciolfi","first_name":"Riccardo","full_name":"Ciolfi, Riccardo"},{"first_name":"Wei K.","last_name":"Cui","full_name":"Cui, Wei K."},{"full_name":"D’Ammando, Filippo","last_name":"D’Ammando","first_name":"Filippo"},{"full_name":"Dauser, Thomas","last_name":"Dauser","first_name":"Thomas"},{"full_name":"Del Santo, Melania","last_name":"Del Santo","first_name":"Melania"},{"last_name":"De Marco","first_name":"Barbara","full_name":"De Marco, Barbara"},{"first_name":"Tiziana","last_name":"Di Salvo","full_name":"Di Salvo, Tiziana"},{"full_name":"Done, Chris","first_name":"Chris","last_name":"Done"},{"last_name":"Dovčiak","first_name":"Michal","full_name":"Dovčiak, Michal"},{"full_name":"Fabian, Andrew C.","last_name":"Fabian","first_name":"Andrew C."},{"full_name":"Falanga, Maurizio","first_name":"Maurizio","last_name":"Falanga"},{"last_name":"Gambino","first_name":"Angelo Francesco","full_name":"Gambino, Angelo Francesco"},{"full_name":"Gendre, Bruce","last_name":"Gendre","first_name":"Bruce"},{"full_name":"Grinberg, Victoria","first_name":"Victoria","last_name":"Grinberg"},{"full_name":"Heger, Alexander","first_name":"Alexander","last_name":"Heger"},{"full_name":"Homan, Jeroen","first_name":"Jeroen","last_name":"Homan"},{"last_name":"Iaria","first_name":"Rosario","full_name":"Iaria, Rosario"},{"full_name":"Jiang, JiaChen","first_name":"JiaChen","last_name":"Jiang"},{"full_name":"Jin, ChiChuan","last_name":"Jin","first_name":"ChiChuan"},{"full_name":"Koerding, Elmar","last_name":"Koerding","first_name":"Elmar"},{"last_name":"Linares","first_name":"Manu","full_name":"Linares, Manu"},{"first_name":"Zhu","last_name":"Liu","full_name":"Liu, Zhu"},{"last_name":"Maccarone","first_name":"Thomas J.","full_name":"Maccarone, Thomas J."},{"full_name":"Malzac, Julien","first_name":"Julien","last_name":"Malzac"},{"last_name":"Manousakis","first_name":"Antonios","full_name":"Manousakis, Antonios"},{"first_name":"Frédéric","last_name":"Marin","full_name":"Marin, Frédéric"},{"full_name":"Marinucci, Andrea","last_name":"Marinucci","first_name":"Andrea"},{"full_name":"Mehdipour, Missagh","last_name":"Mehdipour","first_name":"Missagh"},{"full_name":"Méndez, Mariano","first_name":"Mariano","last_name":"Méndez"},{"last_name":"Migliari","first_name":"Simone","full_name":"Migliari, Simone"},{"full_name":"Miller, Cole","first_name":"Cole","last_name":"Miller"},{"full_name":"Miniutti, Giovanni","first_name":"Giovanni","last_name":"Miniutti"},{"full_name":"Nardini, Emanuele","last_name":"Nardini","first_name":"Emanuele"},{"last_name":"O’Brien","first_name":"Paul T.","full_name":"O’Brien, Paul T."},{"first_name":"Julian P.","last_name":"Osborne","full_name":"Osborne, Julian P."},{"full_name":"Petrucci, Pierre Olivier","first_name":"Pierre Olivier","last_name":"Petrucci"},{"full_name":"Possenti, Andrea","first_name":"Andrea","last_name":"Possenti"},{"full_name":"Riggio, Alessandro","last_name":"Riggio","first_name":"Alessandro"},{"last_name":"Rodriguez","first_name":"Jerome","full_name":"Rodriguez, Jerome"},{"last_name":"Sanna","first_name":"Andrea","full_name":"Sanna, Andrea"},{"last_name":"Shao","first_name":"LiJing","full_name":"Shao, LiJing"},{"full_name":"Sobolewska, Malgosia","first_name":"Malgosia","last_name":"Sobolewska"},{"full_name":"Sramkova, Eva","first_name":"Eva","last_name":"Sramkova"},{"full_name":"Stevens, Abigail L.","last_name":"Stevens","first_name":"Abigail L."},{"last_name":"Stiele","first_name":"Holger","full_name":"Stiele, Holger"},{"full_name":"Stratta, Giulia","first_name":"Giulia","last_name":"Stratta"},{"full_name":"Stuchlik, Zdenek","first_name":"Zdenek","last_name":"Stuchlik"},{"full_name":"Svoboda, Jiri","last_name":"Svoboda","first_name":"Jiri"},{"full_name":"Tamburini, Fabrizio","last_name":"Tamburini","first_name":"Fabrizio"},{"full_name":"Tauris, Thomas M.","first_name":"Thomas M.","last_name":"Tauris"},{"full_name":"Tombesi, Francesco","first_name":"Francesco","last_name":"Tombesi"},{"full_name":"Torok, Gabriel","last_name":"Torok","first_name":"Gabriel"},{"first_name":"Martin","last_name":"Urbanec","full_name":"Urbanec, Martin"},{"full_name":"Vincent, Frederic","first_name":"Frederic","last_name":"Vincent"},{"full_name":"Wu, QingWen","last_name":"Wu","first_name":"QingWen"},{"first_name":"Feng","last_name":"Yuan","full_name":"Yuan, Feng"},{"full_name":"in’ t Zand, Jean J. M.","first_name":"Jean J. M.","last_name":"in’ t Zand"},{"last_name":"Zdziarski","first_name":"Andrzej A.","full_name":"Zdziarski, Andrzej A."},{"last_name":"Zhou","first_name":"XinLin","full_name":"Zhou, XinLin"}],"_id":"15232","citation":{"ama":"Rosa AD, Uttley P, Gou L, et al. Accretion in strong field gravity with eXTP. Science China Physics, Mechanics & Astronomy. 2018;62(2). doi:10.1007/s11433-018-9297-0","ieee":"A. D. Rosa et al., “Accretion in strong field gravity with eXTP,” Science China Physics, Mechanics & Astronomy, vol. 62, no. 2. Springer Nature, 2018.","mla":"Rosa, Alessandra De, et al. “Accretion in Strong Field Gravity with EXTP.” Science China Physics, Mechanics & Astronomy, vol. 62, no. 2, 29504, Springer Nature, 2018, doi:10.1007/s11433-018-9297-0.","ista":"Rosa AD et al. 2018. Accretion in strong field gravity with eXTP. Science China Physics, Mechanics & Astronomy. 62(2), 29504.","chicago":"Rosa, Alessandra De, Phil Uttley, LiJun Gou, Yuan Liu, Cosimo Bambi, Didier Barret, Tomaso Belloni, et al. “Accretion in Strong Field Gravity with EXTP.” Science China Physics, Mechanics & Astronomy. Springer Nature, 2018. https://doi.org/10.1007/s11433-018-9297-0.","apa":"Rosa, A. D., Uttley, P., Gou, L., Liu, Y., Bambi, C., Barret, D., … Zhou, X. (2018). Accretion in strong field gravity with eXTP. Science China Physics, Mechanics & Astronomy. Springer Nature. https://doi.org/10.1007/s11433-018-9297-0","short":"A.D. Rosa, P. Uttley, L. Gou, Y. Liu, C. Bambi, D. Barret, T. Belloni, E. Berti, S. Bianchi, I. Caiazzo, P. Casella, M. Feroci, V. Ferrari, L. Gualtieri, J. Heyl, A. Ingram, V. Karas, F. Lu, B. Luo, G. Matt, S. Motta, J. Neilsen, P. Pani, A. Santangelo, X. Shu, J. Wang, J.-M. Wang, Y. Xue, Y. Xu, W. Yuan, Y. Yuan, S.-N. Zhang, S. Zhang, I. Agudo, L. Amati, N. Andersson, C. Baglio, P. Bakala, A. Baykal, S. Bhattacharyya, I. Bombaci, N. Bucciantini, F. Capitanio, R. Ciolfi, W.K. Cui, F. D’Ammando, T. Dauser, M. Del Santo, B. De Marco, T. Di Salvo, C. Done, M. Dovčiak, A.C. Fabian, M. Falanga, A.F. Gambino, B. Gendre, V. Grinberg, A. Heger, J. Homan, R. Iaria, J. Jiang, C. Jin, E. Koerding, M. Linares, Z. Liu, T.J. Maccarone, J. Malzac, A. Manousakis, F. Marin, A. Marinucci, M. Mehdipour, M. Méndez, S. Migliari, C. Miller, G. Miniutti, E. Nardini, P.T. O’Brien, J.P. Osborne, P.O. Petrucci, A. Possenti, A. Riggio, J. Rodriguez, A. Sanna, L. Shao, M. Sobolewska, E. Sramkova, A.L. Stevens, H. Stiele, G. Stratta, Z. Stuchlik, J. Svoboda, F. Tamburini, T.M. Tauris, F. Tombesi, G. Torok, M. Urbanec, F. Vincent, Q. Wu, F. Yuan, J.J.M. in’ t Zand, A.A. Zdziarski, X. Zhou, Science China Physics, Mechanics & Astronomy 62 (2018)."},"keyword":["General Physics and Astronomy"],"article_number":"29504","quality_controlled":"1","scopus_import":"1","type":"journal_article","publisher":"Springer Nature","intvolume":" 62"},{"_id":"15233","author":[{"last_name":"Santangelo","first_name":"Andrea","full_name":"Santangelo, Andrea"},{"first_name":"Silvia","last_name":"Zane","full_name":"Zane, Silvia"},{"last_name":"Feng","first_name":"Hua","full_name":"Feng, Hua"},{"last_name":"Xu","first_name":"RenXin","full_name":"Xu, RenXin"},{"full_name":"Doroshenko, Victor","first_name":"Victor","last_name":"Doroshenko"},{"full_name":"Bozzo, Enrico","first_name":"Enrico","last_name":"Bozzo"},{"first_name":"Ilaria","orcid":"0000-0002-4770-5388","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","last_name":"Caiazzo","full_name":"Caiazzo, Ilaria"},{"full_name":"Zelati, Francesco Coti","first_name":"Francesco Coti","last_name":"Zelati"},{"full_name":"Esposito, Paolo","first_name":"Paolo","last_name":"Esposito"},{"last_name":"González-Caniulef","first_name":"Denis","full_name":"González-Caniulef, Denis"},{"first_name":"Jeremy","last_name":"Heyl","full_name":"Heyl, Jeremy"},{"last_name":"Huppenkothen","first_name":"Daniela","full_name":"Huppenkothen, Daniela"},{"first_name":"Gianluca","last_name":"Israel","full_name":"Israel, Gianluca"},{"full_name":"Li, ZhaoSheng","last_name":"Li","first_name":"ZhaoSheng"},{"full_name":"Lin, Lin","first_name":"Lin","last_name":"Lin"},{"first_name":"Roberto","last_name":"Mignani","full_name":"Mignani, Roberto"},{"full_name":"Rea, Nanda","first_name":"Nanda","last_name":"Rea"},{"full_name":"Orlandini, Mauro","last_name":"Orlandini","first_name":"Mauro"},{"last_name":"Taverna","first_name":"Roberto","full_name":"Taverna, Roberto"},{"full_name":"Tong, Hao","last_name":"Tong","first_name":"Hao"},{"full_name":"Turolla, Roberto","last_name":"Turolla","first_name":"Roberto"},{"full_name":"Baglio, Cristina","last_name":"Baglio","first_name":"Cristina"},{"full_name":"Bernardini, Federico","first_name":"Federico","last_name":"Bernardini"},{"full_name":"Bucciantini, Niccolo’","first_name":"Niccolo’","last_name":"Bucciantini"},{"full_name":"Feroci, Marco","first_name":"Marco","last_name":"Feroci"},{"last_name":"Fürst","first_name":"Felix","full_name":"Fürst, Felix"},{"full_name":"Göğüş, Ersin","first_name":"Ersin","last_name":"Göğüş"},{"full_name":"Güngör, Can","first_name":"Can","last_name":"Güngör"},{"last_name":"Ji","first_name":"Long","full_name":"Ji, Long"},{"full_name":"Lu, FangJun","first_name":"FangJun","last_name":"Lu"},{"last_name":"Manousakis","first_name":"Antonios","full_name":"Manousakis, Antonios"},{"last_name":"Mereghetti","first_name":"Sandro","full_name":"Mereghetti, Sandro"},{"full_name":"Mikusincova, Romana","first_name":"Romana","last_name":"Mikusincova"},{"full_name":"Paul, Biswajit","last_name":"Paul","first_name":"Biswajit"},{"full_name":"Prescod-Weinstein, Chanda","last_name":"Prescod-Weinstein","first_name":"Chanda"},{"first_name":"George","last_name":"Younes","full_name":"Younes, George"},{"full_name":"Tiengo, Andrea","first_name":"Andrea","last_name":"Tiengo"},{"last_name":"Xu","first_name":"YuPeng","full_name":"Xu, YuPeng"},{"full_name":"Watts, Anna","first_name":"Anna","last_name":"Watts"},{"full_name":"Zhang, Shu","last_name":"Zhang","first_name":"Shu"},{"last_name":"Zhan","first_name":"Shuang-Nan","full_name":"Zhan, Shuang-Nan"}],"keyword":["General Physics and Astronomy"],"citation":{"ieee":"A. Santangelo et al., “Physics and astrophysics of strong magnetic field systems with eXTP,” Science China Physics, Mechanics & Astronomy, vol. 62, no. 2. Springer Nature, 2018.","ista":"Santangelo A, Zane S, Feng H, Xu R, Doroshenko V, Bozzo E, Caiazzo I, Zelati FC, Esposito P, González-Caniulef D, Heyl J, Huppenkothen D, Israel G, Li Z, Lin L, Mignani R, Rea N, Orlandini M, Taverna R, Tong H, Turolla R, Baglio C, Bernardini F, Bucciantini N, Feroci M, Fürst F, Göğüş E, Güngör C, Ji L, Lu F, Manousakis A, Mereghetti S, Mikusincova R, Paul B, Prescod-Weinstein C, Younes G, Tiengo A, Xu Y, Watts A, Zhang S, Zhan S-N. 2018. Physics and astrophysics of strong magnetic field systems with eXTP. Science China Physics, Mechanics & Astronomy. 62(2), 29505.","mla":"Santangelo, Andrea, et al. “Physics and Astrophysics of Strong Magnetic Field Systems with EXTP.” Science China Physics, Mechanics & Astronomy, vol. 62, no. 2, 29505, Springer Nature, 2018, doi:10.1007/s11433-018-9234-3.","ama":"Santangelo A, Zane S, Feng H, et al. Physics and astrophysics of strong magnetic field systems with eXTP. Science China Physics, Mechanics & Astronomy. 2018;62(2). doi:10.1007/s11433-018-9234-3","apa":"Santangelo, A., Zane, S., Feng, H., Xu, R., Doroshenko, V., Bozzo, E., … Zhan, S.-N. (2018). Physics and astrophysics of strong magnetic field systems with eXTP. Science China Physics, Mechanics & Astronomy. Springer Nature. https://doi.org/10.1007/s11433-018-9234-3","short":"A. Santangelo, S. Zane, H. Feng, R. Xu, V. Doroshenko, E. Bozzo, I. Caiazzo, F.C. Zelati, P. Esposito, D. González-Caniulef, J. Heyl, D. Huppenkothen, G. Israel, Z. Li, L. Lin, R. Mignani, N. Rea, M. Orlandini, R. Taverna, H. Tong, R. Turolla, C. Baglio, F. Bernardini, N. Bucciantini, M. Feroci, F. Fürst, E. Göğüş, C. Güngör, L. Ji, F. Lu, A. Manousakis, S. Mereghetti, R. Mikusincova, B. Paul, C. Prescod-Weinstein, G. Younes, A. Tiengo, Y. Xu, A. Watts, S. Zhang, S.-N. Zhan, Science China Physics, Mechanics & Astronomy 62 (2018).","chicago":"Santangelo, Andrea, Silvia Zane, Hua Feng, RenXin Xu, Victor Doroshenko, Enrico Bozzo, Ilaria Caiazzo, et al. “Physics and Astrophysics of Strong Magnetic Field Systems with EXTP.” Science China Physics, Mechanics & Astronomy. Springer Nature, 2018. https://doi.org/10.1007/s11433-018-9234-3."},"article_number":"29505","quality_controlled":"1","scopus_import":"1","type":"journal_article","publisher":"Springer Nature","intvolume":" 62","publication":"Science China Physics, Mechanics & Astronomy","year":"2018","volume":62,"title":"Physics and astrophysics of strong magnetic field systems with eXTP","article_type":"original","external_id":{"arxiv":["1812.04460"]},"publication_identifier":{"eissn":["1869-1927"],"issn":["1674-7348"]},"article_processing_charge":"No","date_created":"2024-03-26T10:38:05Z","language":[{"iso":"eng"}],"oa":1,"arxiv":1,"oa_version":"Preprint","date_updated":"2024-04-08T07:01:20Z","issue":"2","day":"08","status":"public","date_published":"2018-10-08T00:00:00Z","extern":"1","abstract":[{"text":"In this paper we present the science potential of the enhanced X-ray Timing and Polarimetry (eXTP) mission for studies of strongly magnetized objects. We will focus on the physics and astrophysics of strongly magnetized objects, namely magnetars, accreting X-ray pulsars, and rotation powered pulsars. We also discuss the science potential of eXTP for QED studies. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Sciences, the eXTP mission is expected to be launched in the mid 2020s.","lang":"eng"}],"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1007/s11433-018-9234-3","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.1812.04460"}],"month":"10"},{"author":[{"full_name":"Polshyn, Hryhoriy","first_name":"Hryhoriy","orcid":"0000-0001-8223-8896","last_name":"Polshyn","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"last_name":"Zhou","first_name":"H.","full_name":"Zhou, H."},{"last_name":"Spanton","first_name":"E. M.","full_name":"Spanton, E. M."},{"first_name":"T.","last_name":"Taniguchi","full_name":"Taniguchi, T."},{"last_name":"Watanabe","first_name":"K.","full_name":"Watanabe, K."},{"last_name":"Young","first_name":"A. F.","full_name":"Young, A. F."}],"_id":"10626","citation":{"chicago":"Polshyn, Hryhoriy, H. Zhou, E. M. Spanton, T. Taniguchi, K. Watanabe, and A. F. Young. “Quantitative Transport Measurements of Fractional Quantum Hall Energy Gaps in Edgeless Graphene Devices.” Physical Review Letters. American Physical Society, 2018. https://doi.org/10.1103/physrevlett.121.226801.","short":"H. Polshyn, H. Zhou, E.M. Spanton, T. Taniguchi, K. Watanabe, A.F. Young, Physical Review Letters 121 (2018).","apa":"Polshyn, H., Zhou, H., Spanton, E. M., Taniguchi, T., Watanabe, K., & Young, A. F. (2018). Quantitative transport measurements of fractional quantum Hall energy gaps in edgeless graphene devices. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.121.226801","ama":"Polshyn H, Zhou H, Spanton EM, Taniguchi T, Watanabe K, Young AF. Quantitative transport measurements of fractional quantum Hall energy gaps in edgeless graphene devices. Physical Review Letters. 2018;121(22). doi:10.1103/physrevlett.121.226801","ieee":"H. Polshyn, H. Zhou, E. M. Spanton, T. Taniguchi, K. Watanabe, and A. F. Young, “Quantitative transport measurements of fractional quantum Hall energy gaps in edgeless graphene devices,” Physical Review Letters, vol. 121, no. 22. American Physical Society, 2018.","mla":"Polshyn, Hryhoriy, et al. “Quantitative Transport Measurements of Fractional Quantum Hall Energy Gaps in Edgeless Graphene Devices.” Physical Review Letters, vol. 121, no. 22, 226801, American Physical Society, 2018, doi:10.1103/physrevlett.121.226801.","ista":"Polshyn H, Zhou H, Spanton EM, Taniguchi T, Watanabe K, Young AF. 2018. Quantitative transport measurements of fractional quantum Hall energy gaps in edgeless graphene devices. Physical Review Letters. 121(22), 226801."},"keyword":["general physics and astronomy"],"quality_controlled":"1","article_number":"226801","scopus_import":"1","type":"journal_article","publisher":"American Physical Society","intvolume":" 121","year":"2018","publication":"Physical Review Letters","title":"Quantitative transport measurements of fractional quantum Hall energy gaps in edgeless graphene devices","article_type":"original","external_id":{"arxiv":["1805.04199"]},"volume":121,"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"date_created":"2022-01-14T12:15:47Z","acknowledgement":"We thank Cory Dean, S. Chen, Y. Zeng, M. Yankowitz, and J. Li for discussing their unpublished data and for sharing the stack inversion technique. The authors acknowledge further discussions of the results with I. Sodemann, M. Zaletel, C. Nayak, and J. Jain. A. F. Y., H. P., H. Z., and E. M. S. were supported by the ARO under awards 69188PHH and MURI W911NF-17-1-0323. A portion of this work was performed at the National High Magnetic Field Laboratory, which is supported by National Science Foundation Cooperative Agreement No. DMR-1644779 and the State of Florida. K. W. and T. T. acknowledge support from the Elemental Strategy Initiative conducted by the MEXT, Japan, and JSPS KAKENHI Grant No. JP15K21722. E. M. S. acknowledges the support of the Elings Prize Fellowship in Science of the California Nanosystems Institute at the University of California, Santa Barbara. A. F. Y. acknowledges the support of the David and Lucile Packard Foundation.","article_processing_charge":"No","oa":1,"language":[{"iso":"eng"}],"arxiv":1,"issue":"22","oa_version":"Preprint","date_updated":"2022-01-14T13:48:35Z","day":"28","status":"public","date_published":"2018-11-28T00:00:00Z","abstract":[{"lang":"eng","text":"Owing to their wide tunability, multiple internal degrees of freedom, and low disorder, graphene heterostructures are emerging as a promising experimental platform for fractional quantum Hall (FQH) studies. Here, we report FQH thermal activation gap measurements in dual graphite-gated monolayer graphene devices fabricated in an edgeless Corbino geometry. In devices with substrate-induced sublattice splitting, we find a tunable crossover between single- and multicomponent FQH states in the zero energy Landau level. Activation gaps in the single-component regime show excellent agreement with numerical calculations using a single broadening parameter \r\nΓ≈7.2K. In the first excited Landau level, in contrast, FQH gaps are strongly influenced by Landau level mixing, and we observe an unexpected valley-ordered state at integer filling ν=−4."}],"publication_status":"published","extern":"1","doi":"10.1103/physrevlett.121.226801","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","main_file_link":[{"url":"https://arxiv.org/abs/1805.04199","open_access":"1"}],"month":"11"},{"day":"19","language":[{"iso":"eng"}],"date_updated":"2021-11-26T15:57:02Z","oa_version":"None","issue":"2","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","doi":"10.1021/acsnano.7b08044","pmid":1,"month":"01","date_published":"2018-01-19T00:00:00Z","status":"public","extern":"1","publication_status":"published","abstract":[{"text":"Nuclear pore complexes (NPCs) form gateways that control molecular exchange between the nucleus and the cytoplasm. They impose a diffusion barrier to macromolecules and enable the selective transport of nuclear transport receptors with bound cargo. The underlying mechanisms that establish these permeability properties remain to be fully elucidated but require unstructured nuclear pore proteins rich in Phe-Gly (FG)-repeat domains of different types, such as FxFG and GLFG. While physical modeling and in vitro approaches have provided a framework for explaining how the FG network contributes to the barrier and transport properties of the NPC, it remains unknown whether the number and/or the spatial positioning of different FG-domains along a cylindrical, ∼40 nm diameter transport channel contributes to their collective properties and function. To begin to answer these questions, we have used DNA origami to build a cylinder that mimics the dimensions of the central transport channel and can house a specified number of FG-domains at specific positions with easily tunable design parameters, such as grafting density and topology. We find the overall morphology of the FG-domain assemblies to be dependent on their chemical composition, determined by the type and density of FG-repeat, and on their architectural confinement provided by the DNA cylinder, largely consistent with here presented molecular dynamics simulations based on a coarse-grained polymer model. In addition, high-speed atomic force microscopy reveals local and reversible FG-domain condensation that transiently occludes the lumen of the DNA central channel mimics, suggestive of how the NPC might establish its permeability properties.","lang":"eng"}],"type":"journal_article","intvolume":" 12","publisher":"American Chemical Society","_id":"10362","author":[{"first_name":"Patrick D. Ellis","last_name":"Fisher","full_name":"Fisher, Patrick D. Ellis"},{"full_name":"Shen, Qi","first_name":"Qi","last_name":"Shen"},{"full_name":"Akpinar, Bernice","first_name":"Bernice","last_name":"Akpinar"},{"full_name":"Davis, Luke K.","first_name":"Luke K.","last_name":"Davis"},{"full_name":"Chung, Kenny Kwok Hin","first_name":"Kenny Kwok Hin","last_name":"Chung"},{"full_name":"Baddeley, David","first_name":"David","last_name":"Baddeley"},{"first_name":"Anđela","orcid":"0000-0002-7854-2139","last_name":"Šarić","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","full_name":"Šarić, Anđela"},{"first_name":"Thomas J.","last_name":"Melia","full_name":"Melia, Thomas J."},{"full_name":"Hoogenboom, Bart W.","first_name":"Bart W.","last_name":"Hoogenboom"},{"full_name":"Lin, Chenxiang","last_name":"Lin","first_name":"Chenxiang"},{"last_name":"Lusk","first_name":"C. Patrick","full_name":"Lusk, C. Patrick"}],"scopus_import":"1","quality_controlled":"1","keyword":["general physics and astronomy"],"citation":{"chicago":"Fisher, Patrick D. Ellis, Qi Shen, Bernice Akpinar, Luke K. Davis, Kenny Kwok Hin Chung, David Baddeley, Anđela Šarić, et al. “A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement.” ACS Nano. American Chemical Society, 2018. https://doi.org/10.1021/acsnano.7b08044.","short":"P.D.E. Fisher, Q. Shen, B. Akpinar, L.K. Davis, K.K.H. Chung, D. Baddeley, A. Šarić, T.J. Melia, B.W. Hoogenboom, C. Lin, C.P. Lusk, ACS Nano 12 (2018) 1508–1518.","apa":"Fisher, P. D. E., Shen, Q., Akpinar, B., Davis, L. K., Chung, K. K. H., Baddeley, D., … Lusk, C. P. (2018). A Programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement. ACS Nano. American Chemical Society. https://doi.org/10.1021/acsnano.7b08044","ama":"Fisher PDE, Shen Q, Akpinar B, et al. A Programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement. ACS Nano. 2018;12(2):1508-1518. doi:10.1021/acsnano.7b08044","ieee":"P. D. E. Fisher et al., “A Programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement,” ACS Nano, vol. 12, no. 2. American Chemical Society, pp. 1508–1518, 2018.","mla":"Fisher, Patrick D. Ellis, et al. “A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement.” ACS Nano, vol. 12, no. 2, American Chemical Society, 2018, pp. 1508–18, doi:10.1021/acsnano.7b08044.","ista":"Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia TJ, Hoogenboom BW, Lin C, Lusk CP. 2018. A Programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement. ACS Nano. 12(2), 1508–1518."},"article_processing_charge":"No","date_created":"2021-11-26T15:15:00Z","acknowledgement":"We thank J. Edel and members of the Lusk, Lin and Hoogenboom lab for discussion and acknowledge A. Pyne and R. Thorogate for support carrying out the AFM experiments. This work was funded by the NIH (R21GM109466 to CPL, CL and TJM, DP2GM114830 to CL, RO1GM105672 to CPL, and T32GM007223 to PDEF) and the UK Engineering and Physical Sciences Research Council (EP/L015277/1, EP/L504889/1, and EP/M028100/1).","publication_identifier":{"eissn":["1936-086X"],"issn":["1936-0851"]},"volume":12,"external_id":{"pmid":["29350911"]},"article_type":"original","title":"A Programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement","publication":"ACS Nano","year":"2018","page":"1508-1518"},{"type":"journal_article","publisher":"The Royal Society","day":"28","intvolume":" 376","language":[{"iso":"eng"}],"_id":"8419","author":[{"id":"FE553552-CDE8-11E9-B324-C0EBE5697425","last_name":"Kaloshin","orcid":"0000-0002-6051-2628","first_name":"Vadim","full_name":"Kaloshin, Vadim"},{"last_name":"Sorrentino","first_name":"Alfonso","full_name":"Sorrentino, Alfonso"}],"keyword":["General Engineering","General Physics and Astronomy","General Mathematics"],"citation":{"chicago":"Kaloshin, Vadim, and Alfonso Sorrentino. “On the Integrability of Birkhoff Billiards.” Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. The Royal Society, 2018. https://doi.org/10.1098/rsta.2017.0419.","apa":"Kaloshin, V., & Sorrentino, A. (2018). On the integrability of Birkhoff billiards. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. The Royal Society. https://doi.org/10.1098/rsta.2017.0419","short":"V. Kaloshin, A. Sorrentino, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 376 (2018).","ama":"Kaloshin V, Sorrentino A. On the integrability of Birkhoff billiards. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 2018;376(2131). doi:10.1098/rsta.2017.0419","ista":"Kaloshin V, Sorrentino A. 2018. On the integrability of Birkhoff billiards. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 376(2131), 20170419.","ieee":"V. Kaloshin and A. Sorrentino, “On the integrability of Birkhoff billiards,” Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 376, no. 2131. The Royal Society, 2018.","mla":"Kaloshin, Vadim, and Alfonso Sorrentino. “On the Integrability of Birkhoff Billiards.” Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 376, no. 2131, 20170419, The Royal Society, 2018, doi:10.1098/rsta.2017.0419."},"article_number":"20170419","quality_controlled":"1","oa_version":"None","date_updated":"2021-01-12T08:19:09Z","issue":"2131","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1098/rsta.2017.0419","publication_identifier":{"issn":["1364-503X","1471-2962"]},"article_processing_charge":"No","month":"10","date_created":"2020-09-17T10:42:01Z","publication":"Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences","status":"public","year":"2018","volume":376,"date_published":"2018-10-28T00:00:00Z","title":"On the integrability of Birkhoff billiards","article_type":"original","extern":"1","abstract":[{"lang":"eng","text":"In this survey, we provide a concise introduction to convex billiards and describe some recent results, obtained by the authors and collaborators, on the classification of integrable billiards, namely the so-called Birkhoff conjecture.\r\n\r\nThis article is part of the theme issue ‘Finite dimensional integrable systems: new trends and methods’."}],"publication_status":"published"},{"page":"5214-5234","article_type":"original","external_id":{"arxiv":["1706.07968"]},"title":"Density of convex billiards with rational caustics","volume":31,"year":"2018","publication":"Nonlinearity","date_created":"2020-09-17T10:42:09Z","article_processing_charge":"No","publication_identifier":{"issn":["0951-7715","1361-6544"]},"quality_controlled":"1","citation":{"short":"V. Kaloshin, K. Zhang, Nonlinearity 31 (2018) 5214–5234.","apa":"Kaloshin, V., & Zhang, K. (2018). Density of convex billiards with rational caustics. Nonlinearity. IOP Publishing. https://doi.org/10.1088/1361-6544/aadc12","chicago":"Kaloshin, Vadim, and Ke Zhang. “Density of Convex Billiards with Rational Caustics.” Nonlinearity. IOP Publishing, 2018. https://doi.org/10.1088/1361-6544/aadc12.","ista":"Kaloshin V, Zhang K. 2018. Density of convex billiards with rational caustics. Nonlinearity. 31(11), 5214–5234.","ieee":"V. Kaloshin and K. Zhang, “Density of convex billiards with rational caustics,” Nonlinearity, vol. 31, no. 11. IOP Publishing, pp. 5214–5234, 2018.","mla":"Kaloshin, Vadim, and Ke Zhang. “Density of Convex Billiards with Rational Caustics.” Nonlinearity, vol. 31, no. 11, IOP Publishing, 2018, pp. 5214–34, doi:10.1088/1361-6544/aadc12.","ama":"Kaloshin V, Zhang K. Density of convex billiards with rational caustics. Nonlinearity. 2018;31(11):5214-5234. doi:10.1088/1361-6544/aadc12"},"keyword":["Mathematical Physics","General Physics and Astronomy","Applied Mathematics","Statistical and Nonlinear Physics"],"author":[{"full_name":"Kaloshin, Vadim","first_name":"Vadim","orcid":"0000-0002-6051-2628","last_name":"Kaloshin","id":"FE553552-CDE8-11E9-B324-C0EBE5697425"},{"last_name":"Zhang","first_name":"Ke","full_name":"Zhang, Ke"}],"_id":"8420","intvolume":" 31","publisher":"IOP Publishing","type":"journal_article","abstract":[{"text":"We show that in the space of all convex billiard boundaries, the set of boundaries with rational caustics is dense. More precisely, the set of billiard boundaries with caustics of rotation number 1/q is polynomially sense in the smooth case, and exponentially dense in the analytic case.","lang":"eng"}],"publication_status":"published","extern":"1","date_published":"2018-10-15T00:00:00Z","status":"public","month":"10","main_file_link":[{"url":"https://arxiv.org/abs/1706.07968","open_access":"1"}],"doi":"10.1088/1361-6544/aadc12","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"11","date_updated":"2021-01-12T08:19:10Z","oa_version":"Preprint","arxiv":1,"oa":1,"language":[{"iso":"eng"}],"day":"15"},{"oa_version":"Preprint","date_updated":"2023-08-22T08:21:10Z","issue":"20","arxiv":1,"oa":1,"language":[{"iso":"eng"}],"day":"17","extern":"1","publication_status":"published","abstract":[{"lang":"eng","text":"High-harmonic spectroscopy driven by circularly polarized laser pulses and their counterrotating second harmonic is a new branch of attosecond science which currently lacks quantitative interpretations. We extend this technique to the midinfrared regime and record detailed high-harmonic spectra of several rare-gas atoms. These results are compared with the solution of the Schrödinger equation in three dimensions and calculations based on the strong-field approximation that incorporate accurate scattering-wave recombination matrix elements. A quantum-orbit analysis of these results provides a transparent interpretation of the measured intensity ratios of symmetry-allowed neighboring harmonics in terms of (i) a set of propensity rules related to the angular momentum of the atomic orbitals, (ii) atom-specific matrix elements related to their electronic structure, and (iii) the interference of the emissions associated with electrons in orbitals corotating or counterrotating with the laser fields. These results provide the foundation for a quantitative understanding of bicircular high-harmonic spectroscopy."}],"date_published":"2017-11-17T00:00:00Z","status":"public","month":"11","main_file_link":[{"url":"https://arxiv.org/abs/1710.04474","open_access":"1"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1103/physrevlett.119.203201","quality_controlled":"1","article_number":"203201","scopus_import":"1","keyword":["General Physics and Astronomy"],"citation":{"short":"D.R. Baykusheva, S. Brennecke, M. Lein, H.J. Wörner, Physical Review Letters 119 (2017).","apa":"Baykusheva, D. R., Brennecke, S., Lein, M., & Wörner, H. J. (2017). Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.119.203201","chicago":"Baykusheva, Denitsa Rangelova, Simon Brennecke, Manfred Lein, and Hans Jakob Wörner. “Signatures of Electronic Structure in Bicircular High-Harmonic Spectroscopy.” Physical Review Letters. American Physical Society, 2017. https://doi.org/10.1103/physrevlett.119.203201.","ista":"Baykusheva DR, Brennecke S, Lein M, Wörner HJ. 2017. Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 119(20), 203201.","ieee":"D. R. Baykusheva, S. Brennecke, M. Lein, and H. J. Wörner, “Signatures of electronic structure in bicircular high-harmonic spectroscopy,” Physical Review Letters, vol. 119, no. 20. American Physical Society, 2017.","mla":"Baykusheva, Denitsa Rangelova, et al. “Signatures of Electronic Structure in Bicircular High-Harmonic Spectroscopy.” Physical Review Letters, vol. 119, no. 20, 203201, American Physical Society, 2017, doi:10.1103/physrevlett.119.203201.","ama":"Baykusheva DR, Brennecke S, Lein M, Wörner HJ. Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 2017;119(20). doi:10.1103/physrevlett.119.203201"},"_id":"14004","author":[{"full_name":"Baykusheva, Denitsa Rangelova","first_name":"Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva"},{"last_name":"Brennecke","first_name":"Simon","full_name":"Brennecke, Simon"},{"first_name":"Manfred","last_name":"Lein","full_name":"Lein, Manfred"},{"full_name":"Wörner, Hans Jakob","last_name":"Wörner","first_name":"Hans Jakob"}],"intvolume":" 119","publisher":"American Physical Society","type":"journal_article","volume":119,"title":"Signatures of electronic structure in bicircular high-harmonic spectroscopy","external_id":{"arxiv":["1710.04474"]},"article_type":"original","publication":"Physical Review Letters","year":"2017","article_processing_charge":"No","date_created":"2023-08-10T06:35:51Z","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]}},{"date_created":"2023-08-10T06:36:09Z","article_processing_charge":"No","publication_identifier":{"eissn":["2041-1723"]},"title":"Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering","external_id":{"pmid":["28643771"]},"article_type":"original","volume":8,"year":"2017","publication":"Nature Communications","intvolume":" 8","publisher":"Springer Nature","type":"journal_article","quality_controlled":"1","scopus_import":"1","article_number":"15651","citation":{"mla":"Walt, Samuel G., et al. “Dynamics of Valence-Shell Electrons and Nuclei Probed by Strong-Field Holography and Rescattering.” Nature Communications, vol. 8, 15651, Springer Nature, 2017, doi:10.1038/ncomms15651.","ista":"Walt SG, Bhargava Ram N, Atala M, Shvetsov-Shilovski NI, von Conta A, Baykusheva DR, Lein M, Wörner HJ. 2017. Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering. Nature Communications. 8, 15651.","ieee":"S. G. Walt et al., “Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering,” Nature Communications, vol. 8. Springer Nature, 2017.","ama":"Walt SG, Bhargava Ram N, Atala M, et al. Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering. Nature Communications. 2017;8. doi:10.1038/ncomms15651","short":"S.G. Walt, N. Bhargava Ram, M. Atala, N.I. Shvetsov-Shilovski, A. von Conta, D.R. Baykusheva, M. Lein, H.J. Wörner, Nature Communications 8 (2017).","apa":"Walt, S. G., Bhargava Ram, N., Atala, M., Shvetsov-Shilovski, N. I., von Conta, A., Baykusheva, D. R., … Wörner, H. J. (2017). Dynamics of valence-shell electrons and nuclei probed by strong-field holography and rescattering. Nature Communications. Springer Nature. https://doi.org/10.1038/ncomms15651","chicago":"Walt, Samuel G., Niraghatam Bhargava Ram, Marcos Atala, Nikolay I Shvetsov-Shilovski, Aaron von Conta, Denitsa Rangelova Baykusheva, Manfred Lein, and Hans Jakob Wörner. “Dynamics of Valence-Shell Electrons and Nuclei Probed by Strong-Field Holography and Rescattering.” Nature Communications. Springer Nature, 2017. https://doi.org/10.1038/ncomms15651."},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"author":[{"first_name":"Samuel G.","last_name":"Walt","full_name":"Walt, Samuel G."},{"last_name":"Bhargava Ram","first_name":"Niraghatam","full_name":"Bhargava Ram, Niraghatam"},{"full_name":"Atala, Marcos","first_name":"Marcos","last_name":"Atala"},{"first_name":"Nikolay I","last_name":"Shvetsov-Shilovski","full_name":"Shvetsov-Shilovski, Nikolay I"},{"first_name":"Aaron","last_name":"von Conta","full_name":"von Conta, Aaron"},{"full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","first_name":"Denitsa Rangelova"},{"first_name":"Manfred","last_name":"Lein","full_name":"Lein, Manfred"},{"last_name":"Wörner","first_name":"Hans Jakob","full_name":"Wörner, Hans Jakob"}],"_id":"14005","month":"06","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/ncomms15651"}],"pmid":1,"doi":"10.1038/ncomms15651","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Strong-field photoelectron holography and laser-induced electron diffraction (LIED) are two powerful emerging methods for probing the ultrafast dynamics of molecules. However, both of them have remained restricted to static systems and to nuclear dynamics induced by strong-field ionization. Here we extend these promising methods to image purely electronic valence-shell dynamics in molecules using photoelectron holography. In the same experiment, we use LIED and photoelectron holography simultaneously, to observe coupled electronic-rotational dynamics taking place on similar timescales. These results offer perspectives for imaging ultrafast dynamics of molecules on femtosecond to attosecond timescales.","lang":"eng"}],"publication_status":"published","extern":"1","date_published":"2017-06-15T00:00:00Z","status":"public","day":"15","date_updated":"2023-08-22T08:26:06Z","oa_version":"Published Version","language":[{"iso":"eng"}],"oa":1},{"status":"public","date_published":"2017-03-28T00:00:00Z","abstract":[{"text":"We present a theoretical formalism for the calculation of attosecond delays in molecular photoionization. It is shown how delays relevant to one-photon-ionization, also known as Eisenbud-Wigner-Smith delays, can be obtained from the complex dipole matrix elements provided by molecular quantum scattering theory. These results are used to derive formulae for the delays measured by two-photon attosecond interferometry based on an attosecond pulse train and a dressing femtosecond infrared pulse. These effective delays are first expressed in the molecular frame where maximal information about the molecular photoionization dynamics is available. The effects of averaging over the emission direction of the electron and the molecular orientation are introduced analytically. We illustrate this general formalism for the case of two polyatomic molecules. N2O serves as an example of a polar linear molecule characterized by complex photoionization dynamics resulting from the presence of molecular shape resonances. H2O illustrates the case of a non-linear molecule with comparably simple photoionization dynamics resulting from a flat continuum. Our theory establishes the foundation for interpreting measurements of the photoionization dynamics of all molecules by attosecond metrology.","lang":"eng"}],"publication_status":"published","extern":"1","doi":"10.1063/1.4977933","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"03","language":[{"iso":"eng"}],"issue":"12","oa_version":"None","date_updated":"2023-08-22T08:30:59Z","day":"28","year":"2017","publication":"The Journal of Chemical Physics","article_type":"original","title":"Theory of attosecond delays in molecular photoionization","external_id":{"pmid":["28388142"]},"volume":146,"publication_identifier":{"eissn":["1089-7690"],"issn":["0021-9606"]},"date_created":"2023-08-10T06:36:19Z","article_processing_charge":"No","author":[{"full_name":"Baykusheva, Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","first_name":"Denitsa Rangelova"},{"full_name":"Wörner, Hans Jakob","first_name":"Hans Jakob","last_name":"Wörner"}],"_id":"14006","citation":{"short":"D.R. Baykusheva, H.J. Wörner, The Journal of Chemical Physics 146 (2017).","apa":"Baykusheva, D. R., & Wörner, H. J. (2017). Theory of attosecond delays in molecular photoionization. The Journal of Chemical Physics. AIP Publishing. https://doi.org/10.1063/1.4977933","chicago":"Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Theory of Attosecond Delays in Molecular Photoionization.” The Journal of Chemical Physics. AIP Publishing, 2017. https://doi.org/10.1063/1.4977933.","ista":"Baykusheva DR, Wörner HJ. 2017. Theory of attosecond delays in molecular photoionization. The Journal of Chemical Physics. 146(12), 124306.","mla":"Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Theory of Attosecond Delays in Molecular Photoionization.” The Journal of Chemical Physics, vol. 146, no. 12, 124306, AIP Publishing, 2017, doi:10.1063/1.4977933.","ieee":"D. R. Baykusheva and H. J. Wörner, “Theory of attosecond delays in molecular photoionization,” The Journal of Chemical Physics, vol. 146, no. 12. AIP Publishing, 2017.","ama":"Baykusheva DR, Wörner HJ. Theory of attosecond delays in molecular photoionization. The Journal of Chemical Physics. 2017;146(12). doi:10.1063/1.4977933"},"keyword":["Physical and Theoretical Chemistry","General Physics and Astronomy"],"scopus_import":"1","article_number":"124306","quality_controlled":"1","type":"journal_article","publisher":"AIP Publishing","intvolume":" 146"},{"publication":"Physical Review Letters","year":"2017","volume":119,"article_type":"original","title":"Signatures of electronic structure in bicircular high-harmonic spectroscopy","external_id":{"pmid":["29219334"],"arxiv":["1710.04474"]},"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"article_processing_charge":"No","date_created":"2023-08-10T06:48:12Z","keyword":["General Physics and Astronomy"],"citation":{"mla":"Baykusheva, Denitsa Rangelova, et al. “Signatures of Electronic Structure in Bicircular High-Harmonic Spectroscopy.” Physical Review Letters, vol. 119, no. 20, 203201, American Physical Society, 2017, doi:10.1103/physrevlett.119.203201.","ista":"Baykusheva DR, Brennecke S, Lein M, Wörner HJ. 2017. Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 119(20), 203201.","ieee":"D. R. Baykusheva, S. Brennecke, M. Lein, and H. J. Wörner, “Signatures of electronic structure in bicircular high-harmonic spectroscopy,” Physical Review Letters, vol. 119, no. 20. American Physical Society, 2017.","ama":"Baykusheva DR, Brennecke S, Lein M, Wörner HJ. Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 2017;119(20). doi:10.1103/physrevlett.119.203201","short":"D.R. Baykusheva, S. Brennecke, M. Lein, H.J. Wörner, Physical Review Letters 119 (2017).","apa":"Baykusheva, D. R., Brennecke, S., Lein, M., & Wörner, H. J. (2017). Signatures of electronic structure in bicircular high-harmonic spectroscopy. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.119.203201","chicago":"Baykusheva, Denitsa Rangelova, Simon Brennecke, Manfred Lein, and Hans Jakob Wörner. “Signatures of Electronic Structure in Bicircular High-Harmonic Spectroscopy.” Physical Review Letters. American Physical Society, 2017. https://doi.org/10.1103/physrevlett.119.203201."},"scopus_import":"1","article_number":"203201","quality_controlled":"1","_id":"14031","author":[{"full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","first_name":"Denitsa Rangelova"},{"full_name":"Brennecke, Simon","last_name":"Brennecke","first_name":"Simon"},{"full_name":"Lein, Manfred","first_name":"Manfred","last_name":"Lein"},{"last_name":"Wörner","first_name":"Hans Jakob","full_name":"Wörner, Hans Jakob"}],"publisher":"American Physical Society","intvolume":" 119","type":"journal_article","extern":"1","abstract":[{"text":"High-harmonic spectroscopy driven by circularly polarized laser pulses and their counterrotating second harmonic is a new branch of attosecond science which currently lacks quantitative interpretations. We extend this technique to the midinfrared regime and record detailed high-harmonic spectra of several rare-gas atoms. These results are compared with the solution of the Schrödinger equation in three dimensions and calculations based on the strong-field approximation that incorporate accurate scattering-wave recombination matrix elements. A quantum-orbit analysis of these results provides a transparent interpretation of the measured intensity ratios of symmetry-allowed neighboring harmonics in terms of (i) a set of propensity rules related to the angular momentum of the atomic orbitals, (ii) atom-specific matrix elements related to their electronic structure, and (iii) the interference of the emissions associated with electrons in orbitals corotating or counterrotating with the laser fields. These results provide the foundation for a quantitative understanding of bicircular high-harmonic spectroscopy.","lang":"eng"}],"publication_status":"published","status":"public","date_published":"2017-11-17T00:00:00Z","main_file_link":[{"url":"https://arxiv.org/abs/1710.04474","open_access":"1"}],"month":"11","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1103/physrevlett.119.203201","pmid":1,"arxiv":1,"date_updated":"2023-08-22T06:48:28Z","oa_version":"Preprint","issue":"20","oa":1,"language":[{"iso":"eng"}],"day":"17"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"doi":"10.1038/s41467-017-00322-z","month":"08","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-017-00322-z"}],"date_published":"2017-08-30T00:00:00Z","status":"public","extern":"1","abstract":[{"lang":"eng","text":"Premature aging disorders provide an opportunity to study the mechanisms that drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins. We sought to investigate protein homeostasis in this disease. Here, we report a widespread increase in protein turnover in HGPS-derived cells compared to normal cells. We determine that global protein synthesis is elevated as a consequence of activated nucleoli and enhanced ribosome biogenesis in HGPS-derived fibroblasts. Depleting normal lamin A or inducing mutant lamin A expression are each sufficient to drive nucleolar expansion. We further show that nucleolar size correlates with donor age in primary fibroblasts derived from healthy individuals and that ribosomal RNA production increases with age, indicating that nucleolar size and activity can serve as aging biomarkers. While limiting ribosome biogenesis extends lifespan in several systems, we show that increased ribosome biogenesis and activity are a hallmark of premature aging."}],"publication_status":"published","day":"30","oa":1,"language":[{"iso":"eng"}],"date_updated":"2024-10-14T11:20:12Z","oa_version":"Published Version","article_processing_charge":"No","date_created":"2022-04-07T07:45:50Z","publication_identifier":{"issn":["2041-1723"]},"volume":8,"title":"Nucleolar expansion and elevated protein translation in premature aging","external_id":{"pmid":["28855503"]},"article_type":"original","publication":"Nature Communications","year":"2017","type":"journal_article","intvolume":" 8","publisher":"Springer Nature","_id":"11065","author":[{"full_name":"Buchwalter, Abigail","first_name":"Abigail","last_name":"Buchwalter"},{"full_name":"HETZER, Martin W","first_name":"Martin W","last_name":"HETZER","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X"}],"article_number":"328","quality_controlled":"1","scopus_import":"1","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"citation":{"ama":"Buchwalter A, Hetzer M. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications. 2017;8. doi:10.1038/s41467-017-00322-z","ieee":"A. Buchwalter and M. Hetzer, “Nucleolar expansion and elevated protein translation in premature aging,” Nature Communications, vol. 8. Springer Nature, 2017.","ista":"Buchwalter A, Hetzer M. 2017. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications. 8, 328.","mla":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” Nature Communications, vol. 8, 328, Springer Nature, 2017, doi:10.1038/s41467-017-00322-z.","chicago":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” Nature Communications. Springer Nature, 2017. https://doi.org/10.1038/s41467-017-00322-z.","apa":"Buchwalter, A., & Hetzer, M. (2017). Nucleolar expansion and elevated protein translation in premature aging. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-017-00322-z","short":"A. Buchwalter, M. Hetzer, Nature Communications 8 (2017)."}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"doi":"10.1103/physrevlett.117.093001","main_file_link":[{"url":"https://arxiv.org/abs/1607.07435","open_access":"1"}],"month":"08","status":"public","date_published":"2016-08-26T00:00:00Z","extern":"1","publication_status":"published","abstract":[{"lang":"eng","text":"We report measurements of energy-dependent attosecond photoionization delays between the two outer-most valence shells of N2O and H2O. The combination of single-shot signal referencing with the use of different metal foils to filter the attosecond pulse train enables us to extract delays from congested spectra. Remarkably large delays up to 160 as are observed in N2O, whereas the delays in H2O are all smaller than 50 as in the photon-energy range of 20-40 eV. These results are interpreted by developing a theory of molecular photoionization delays. The long delays measured in N2O are shown to reflect the population of molecular shape resonances that trap the photoelectron for a duration of up to ∼110 as. The unstructured continua of H2O result in much smaller delays at the same photon energies. Our experimental and theoretical methods make the study of molecular attosecond photoionization dynamics accessible."}],"day":"26","language":[{"iso":"eng"}],"oa":1,"arxiv":1,"date_updated":"2023-08-22T08:42:50Z","oa_version":"Preprint","issue":"9","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"article_processing_charge":"No","date_created":"2023-08-10T06:37:07Z","publication":"Physical Review Letters","year":"2016","volume":117,"external_id":{"arxiv":["1607.07435"],"pmid":["27610849"]},"title":"Attosecond delays in molecular photoionization","article_type":"original","type":"journal_article","publisher":"American Physical Society","intvolume":" 117","_id":"14010","author":[{"full_name":"Huppert, Martin","first_name":"Martin","last_name":"Huppert"},{"full_name":"Jordan, Inga","last_name":"Jordan","first_name":"Inga"},{"first_name":"Denitsa Rangelova","id":"71b4d059-2a03-11ee-914d-dfa3beed6530","last_name":"Baykusheva","full_name":"Baykusheva, Denitsa Rangelova"},{"last_name":"von Conta","first_name":"Aaron","full_name":"von Conta, Aaron"},{"full_name":"Wörner, Hans Jakob","first_name":"Hans Jakob","last_name":"Wörner"}],"keyword":["General Physics and Astronomy"],"citation":{"short":"M. Huppert, I. Jordan, D.R. Baykusheva, A. von Conta, H.J. Wörner, Physical Review Letters 117 (2016).","apa":"Huppert, M., Jordan, I., Baykusheva, D. R., von Conta, A., & Wörner, H. J. (2016). Attosecond delays in molecular photoionization. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.117.093001","chicago":"Huppert, Martin, Inga Jordan, Denitsa Rangelova Baykusheva, Aaron von Conta, and Hans Jakob Wörner. “Attosecond Delays in Molecular Photoionization.” Physical Review Letters. American Physical Society, 2016. https://doi.org/10.1103/physrevlett.117.093001.","ista":"Huppert M, Jordan I, Baykusheva DR, von Conta A, Wörner HJ. 2016. Attosecond delays in molecular photoionization. Physical Review Letters. 117(9), 093001.","mla":"Huppert, Martin, et al. “Attosecond Delays in Molecular Photoionization.” Physical Review Letters, vol. 117, no. 9, 093001, American Physical Society, 2016, doi:10.1103/physrevlett.117.093001.","ieee":"M. Huppert, I. Jordan, D. R. Baykusheva, A. von Conta, and H. J. Wörner, “Attosecond delays in molecular photoionization,” Physical Review Letters, vol. 117, no. 9. American Physical Society, 2016.","ama":"Huppert M, Jordan I, Baykusheva DR, von Conta A, Wörner HJ. Attosecond delays in molecular photoionization. Physical Review Letters. 2016;117(9). doi:10.1103/physrevlett.117.093001"},"quality_controlled":"1","article_number":"093001","scopus_import":"1"},{"publisher":"American Physical Society","intvolume":" 116","type":"journal_article","keyword":["General Physics and Astronomy"],"citation":{"ama":"Baykusheva DR, Ahsan MS, Lin N, Wörner HJ. Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules. Physical Review Letters. 2016;116(12). doi:10.1103/physrevlett.116.123001","ieee":"D. R. Baykusheva, M. S. Ahsan, N. Lin, and H. J. Wörner, “Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules,” Physical Review Letters, vol. 116, no. 12. American Physical Society, 2016.","mla":"Baykusheva, Denitsa Rangelova, et al. “Bicircular High-Harmonic Spectroscopy Reveals Dynamical Symmetries of Atoms and Molecules.” Physical Review Letters, vol. 116, no. 12, 123001, American Physical Society, 2016, doi:10.1103/physrevlett.116.123001.","ista":"Baykusheva DR, Ahsan MS, Lin N, Wörner HJ. 2016. Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules. Physical Review Letters. 116(12), 123001.","chicago":"Baykusheva, Denitsa Rangelova, Md Sabbir Ahsan, Nan Lin, and Hans Jakob Wörner. “Bicircular High-Harmonic Spectroscopy Reveals Dynamical Symmetries of Atoms and Molecules.” Physical Review Letters. American Physical Society, 2016. https://doi.org/10.1103/physrevlett.116.123001.","apa":"Baykusheva, D. R., Ahsan, M. S., Lin, N., & Wörner, H. J. (2016). Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.116.123001","short":"D.R. Baykusheva, M.S. Ahsan, N. Lin, H.J. Wörner, Physical Review Letters 116 (2016)."},"scopus_import":"1","quality_controlled":"1","article_number":"123001","_id":"14011","author":[{"full_name":"Baykusheva, Denitsa Rangelova","first_name":"Denitsa Rangelova","last_name":"Baykusheva","id":"71b4d059-2a03-11ee-914d-dfa3beed6530"},{"full_name":"Ahsan, Md Sabbir","first_name":"Md Sabbir","last_name":"Ahsan"},{"first_name":"Nan","last_name":"Lin","full_name":"Lin, Nan"},{"full_name":"Wörner, Hans Jakob","last_name":"Wörner","first_name":"Hans Jakob"}],"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"article_processing_charge":"No","date_created":"2023-08-10T06:37:16Z","publication":"Physical Review Letters","year":"2016","volume":116,"external_id":{"pmid":["27058077"]},"title":"Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules","article_type":"original","day":"25","oa_version":"None","date_updated":"2023-08-22T08:44:10Z","issue":"12","language":[{"iso":"eng"}],"month":"03","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1103/physrevlett.116.123001","pmid":1,"extern":"1","publication_status":"published","abstract":[{"text":"We introduce bicircular high-harmonic spectroscopy as a new method to probe dynamical symmetries of atoms and molecules and their evolution in time. Our approach is based on combining a circularly polarized femtosecond fundamental field of frequency ω with its counterrotating second harmonic 2ω. We demonstrate the ability of bicircular high-harmonic spectroscopy to characterize the orbital angular momentum symmetry of atomic orbitals. We further show that breaking the threefold rotational symmetry of the generating medium-at the level of either the ensemble or that of a single molecule-results in the emission of the otherwise parity-forbidden frequencies 3qω (q∈N), which provide a background-free probe of dynamical molecular symmetries.","lang":"eng"}],"status":"public","date_published":"2016-03-25T00:00:00Z"},{"user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","pmid":1,"doi":"10.1038/ncomms13874","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/ncomms13874"}],"month":"12","status":"public","date_published":"2016-12-22T00:00:00Z","extern":"1","publication_status":"published","abstract":[{"text":"Spatiotemporal activation of RhoA and actomyosin contraction underpins cellular adhesion and division. Loss of cell–cell adhesion and chromosomal instability are cardinal events that drive tumour progression. Here, we show that p120-catenin (p120) not only controls cell–cell adhesion, but also acts as a critical regulator of cytokinesis. We find that p120 regulates actomyosin contractility through concomitant binding to RhoA and the centralspindlin component MKLP1, independent of cadherin association. In anaphase, p120 is enriched at the cleavage furrow where it binds MKLP1 to spatially control RhoA GTPase cycling. Binding of p120 to MKLP1 during cytokinesis depends on the N-terminal coiled-coil domain of p120 isoform 1A. Importantly, clinical data show that loss of p120 expression is a common event in breast cancer that strongly correlates with multinucleation and adverse patient survival. In summary, our study identifies p120 loss as a driver event of chromosomal instability in cancer.\r\n","lang":"eng"}],"day":"22","oa":1,"language":[{"iso":"eng"}],"date_updated":"2022-07-18T08:34:32Z","oa_version":"Published Version","publication_identifier":{"issn":["2041-1723"]},"article_processing_charge":"No","date_created":"2022-04-07T07:48:34Z","publication":"Nature Communications","year":"2016","volume":7,"title":"p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis","article_type":"original","external_id":{"pmid":["28004812"]},"related_material":{"link":[{"url":"https://doi.org/10.1038/ncomms16030","relation":"erratum"}]},"type":"journal_article","publisher":"Springer Nature","intvolume":" 7","_id":"11072","author":[{"last_name":"van de Ven","first_name":"Robert A.H.","full_name":"van de Ven, Robert A.H."},{"full_name":"de Groot, Jolien S.","first_name":"Jolien S.","last_name":"de Groot"},{"first_name":"Danielle","last_name":"Park","full_name":"Park, Danielle"},{"full_name":"van Domselaar, Robert","last_name":"van Domselaar","first_name":"Robert"},{"full_name":"de Jong, Danielle","last_name":"de Jong","first_name":"Danielle"},{"first_name":"Karoly","last_name":"Szuhai","full_name":"Szuhai, Karoly"},{"first_name":"Elsken","last_name":"van der Wall","full_name":"van der Wall, Elsken"},{"full_name":"Rueda, Oscar M.","first_name":"Oscar M.","last_name":"Rueda"},{"last_name":"Ali","first_name":"H. Raza","full_name":"Ali, H. Raza"},{"full_name":"Caldas, Carlos","first_name":"Carlos","last_name":"Caldas"},{"full_name":"van Diest, Paul J.","first_name":"Paul J.","last_name":"van Diest"},{"id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","last_name":"HETZER","orcid":"0000-0002-2111-992X","first_name":"Martin W","full_name":"HETZER, Martin W"},{"first_name":"Erik","last_name":"Sahai","full_name":"Sahai, Erik"},{"last_name":"Derksen","first_name":"Patrick W.B.","full_name":"Derksen, Patrick W.B."}],"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"citation":{"apa":"van de Ven, R. A. H., de Groot, J. S., Park, D., van Domselaar, R., de Jong, D., Szuhai, K., … Derksen, P. W. B. (2016). p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nature Communications. Springer Nature. https://doi.org/10.1038/ncomms13874","short":"R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).","chicago":"Ven, Robert A.H. van de, Jolien S. de Groot, Danielle Park, Robert van Domselaar, Danielle de Jong, Karoly Szuhai, Elsken van der Wall, et al. “P120-Catenin Prevents Multinucleation through Control of MKLP1-Dependent RhoA Activity during Cytokinesis.” Nature Communications. Springer Nature, 2016. https://doi.org/10.1038/ncomms13874.","ista":"van de Ven RAH, de Groot JS, Park D, van Domselaar R, de Jong D, Szuhai K, van der Wall E, Rueda OM, Ali HR, Caldas C, van Diest PJ, Hetzer M, Sahai E, Derksen PWB. 2016. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nature Communications. 7, 13874.","ieee":"R. A. H. van de Ven et al., “p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis,” Nature Communications, vol. 7. Springer Nature, 2016.","mla":"van de Ven, Robert A. H., et al. “P120-Catenin Prevents Multinucleation through Control of MKLP1-Dependent RhoA Activity during Cytokinesis.” Nature Communications, vol. 7, 13874, Springer Nature, 2016, doi:10.1038/ncomms13874.","ama":"van de Ven RAH, de Groot JS, Park D, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nature Communications. 2016;7. doi:10.1038/ncomms13874"},"article_number":"13874","quality_controlled":"1","scopus_import":"1"},{"keyword":["physical and theoretical chemistry","general physics and astronomy"],"citation":{"mla":"Šarić, Anđela, et al. “Kinetics of Spontaneous Filament Nucleation via Oligomers: Insights from Theory and Simulation.” The Journal of Chemical Physics, vol. 145, no. 21, 211926, American Institute of Physics, 2016, doi:10.1063/1.4965040.","ieee":"A. Šarić, T. C. T. Michaels, A. Zaccone, T. P. J. Knowles, and D. Frenkel, “Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation,” The Journal of Chemical Physics, vol. 145, no. 21. American Institute of Physics, 2016.","ista":"Šarić A, Michaels TCT, Zaccone A, Knowles TPJ, Frenkel D. 2016. Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation. The Journal of Chemical Physics. 145(21), 211926.","ama":"Šarić A, Michaels TCT, Zaccone A, Knowles TPJ, Frenkel D. Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation. The Journal of Chemical Physics. 2016;145(21). doi:10.1063/1.4965040","short":"A. Šarić, T.C.T. Michaels, A. Zaccone, T.P.J. Knowles, D. Frenkel, The Journal of Chemical Physics 145 (2016).","apa":"Šarić, A., Michaels, T. C. T., Zaccone, A., Knowles, T. P. J., & Frenkel, D. (2016). Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation. The Journal of Chemical Physics. American Institute of Physics. https://doi.org/10.1063/1.4965040","chicago":"Šarić, Anđela, Thomas C. T. Michaels, Alessio Zaccone, Tuomas P. J. Knowles, and Daan Frenkel. “Kinetics of Spontaneous Filament Nucleation via Oligomers: Insights from Theory and Simulation.” The Journal of Chemical Physics. American Institute of Physics, 2016. https://doi.org/10.1063/1.4965040."},"quality_controlled":"1","article_number":"211926","scopus_import":"1","_id":"10376","author":[{"full_name":"Šarić, Anđela","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","last_name":"Šarić","orcid":"0000-0002-7854-2139","first_name":"Anđela"},{"first_name":"Thomas C. T.","last_name":"Michaels","full_name":"Michaels, Thomas C. T."},{"last_name":"Zaccone","first_name":"Alessio","full_name":"Zaccone, Alessio"},{"first_name":"Tuomas P. J.","last_name":"Knowles","full_name":"Knowles, Tuomas P. J."},{"full_name":"Frenkel, Daan","last_name":"Frenkel","first_name":"Daan"}],"publisher":"American Institute of Physics","intvolume":" 145","type":"journal_article","publication":"The Journal of Chemical Physics","year":"2016","volume":145,"external_id":{"arxiv":["1610.02320"],"pmid":["28799382"]},"title":"Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation","article_type":"original","publication_identifier":{"issn":["0021-9606"],"eissn":["1089-7690"]},"article_processing_charge":"No","acknowledgement":"We acknowledge support from the Human Frontier Science Program and Emmanuel College (A.Š.), St John’s and Peterhouse Colleges (T.C.T.M.), the Swiss National Science Foundation (T.C.T.M.), the Biotechnology and Biological Sciences Research Council (T.P.J.K.), the Frances and Augustus Newman Foundation (T.P.J.K.), the European Research Council (T.C.T.M., T.P.J.K., and D.F.), and the Engineering and Physical Sciences Research Council (D.F.).","date_created":"2021-11-29T10:01:57Z","arxiv":1,"oa_version":"Preprint","date_updated":"2021-11-29T10:33:11Z","issue":"21","oa":1,"language":[{"iso":"eng"}],"day":"01","extern":"1","publication_status":"published","abstract":[{"lang":"eng","text":"Nucleation processes are at the heart of a large number of phenomena, from cloud formation to protein crystallization. A recently emerging area where nucleation is highly relevant is the initiation of filamentous protein self-assembly, a process that has broad implications in many research areas ranging from medicine to nanotechnology. As such, spontaneous nucleation of protein fibrils has received much attention in recent years with many theoretical and experimental studies focusing on the underlying physical principles. In this paper we make a step forward in this direction and explore the early time behaviour of filamentous protein growth in the context of nucleation theory. We first provide an overview of the thermodynamics and kinetics of spontaneous nucleation of protein filaments in the presence of one relevant degree of freedom, namely the cluster size. In this case, we review how key kinetic observables, such as the reaction order of spontaneous nucleation, are directly related to the physical size of the critical nucleus. We then focus on the increasingly prominent case of filament nucleation that includes a conformational conversion of the nucleating building-block as an additional slow step in the nucleation process. Using computer simulations, we study the concentration dependence of the nucleation rate. We find that, under these circumstances, the reaction order of spontaneous nucleation with respect to the free monomer does no longer relate to the overall physical size of the nucleating aggregate but rather to the portion of the aggregate that actively participates in the conformational conversion. Our results thus provide a novel interpretation of the common kinetic descriptors of protein filament formation, including the reaction order of the nucleation step or the scaling exponent of lag times, and put into perspective current theoretical descriptions of protein aggregation."}],"status":"public","date_published":"2016-12-01T00:00:00Z","main_file_link":[{"url":"https://arxiv.org/abs/1610.02320","open_access":"1"}],"month":"12","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","pmid":1,"doi":"10.1063/1.4965040"},{"day":"18","date_updated":"2021-11-29T11:07:25Z","oa_version":"Preprint","issue":"9","language":[{"iso":"eng"}],"oa":1,"main_file_link":[{"url":"https://discovery.ucl.ac.uk/id/eprint/1517406/","open_access":"1"}],"month":"07","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","pmid":1,"doi":"10.1038/nphys3828","extern":"1","publication_status":"published","abstract":[{"text":"The ability of biological molecules to replicate themselves is the foundation of life, requiring a complex cellular machinery. However, a range of aberrant processes involve the self-replication of pathological protein structures without any additional assistance. One example is the autocatalytic generation of pathological protein aggregates, including amyloid fibrils, involved in neurodegenerative disorders. Here, we use computer simulations to identify the necessary requirements for the self-replication of fibrillar assemblies of proteins. We establish that a key physical determinant for this process is the affinity of proteins for the surfaces of fibrils. We find that self-replication can take place only in a very narrow regime of inter-protein interactions, implying a high level of sensitivity to system parameters and experimental conditions. We then compare our theoretical predictions with kinetic and biosensor measurements of fibrils formed from the Aβ peptide associated with Alzheimer’s disease. Our results show a quantitative connection between the kinetics of self-replication and the surface coverage of fibrils by monomeric proteins. These findings reveal the fundamental physical requirements for the formation of supra-molecular structures able to replicate themselves, and shed light on mechanisms in play in the proliferation of protein aggregates in nature.","lang":"eng"}],"status":"public","date_published":"2016-07-18T00:00:00Z","publisher":"Springer Nature","intvolume":" 12","type":"journal_article","keyword":["general physics and astronomy"],"citation":{"ama":"Šarić A, Buell AK, Meisl G, et al. Physical determinants of the self-replication of protein fibrils. Nature Physics. 2016;12(9):874-880. doi:10.1038/nphys3828","mla":"Šarić, Anđela, et al. “Physical Determinants of the Self-Replication of Protein Fibrils.” Nature Physics, vol. 12, no. 9, Springer Nature, 2016, pp. 874–80, doi:10.1038/nphys3828.","ieee":"A. Šarić et al., “Physical determinants of the self-replication of protein fibrils,” Nature Physics, vol. 12, no. 9. Springer Nature, pp. 874–880, 2016.","ista":"Šarić A, Buell AK, Meisl G, Michaels TCT, Dobson CM, Linse S, Knowles TPJ, Frenkel D. 2016. Physical determinants of the self-replication of protein fibrils. Nature Physics. 12(9), 874–880.","chicago":"Šarić, Anđela, Alexander K. Buell, Georg Meisl, Thomas C. T. Michaels, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles, and Daan Frenkel. “Physical Determinants of the Self-Replication of Protein Fibrils.” Nature Physics. Springer Nature, 2016. https://doi.org/10.1038/nphys3828.","apa":"Šarić, A., Buell, A. K., Meisl, G., Michaels, T. C. T., Dobson, C. M., Linse, S., … Frenkel, D. (2016). Physical determinants of the self-replication of protein fibrils. Nature Physics. Springer Nature. https://doi.org/10.1038/nphys3828","short":"A. Šarić, A.K. Buell, G. Meisl, T.C.T. Michaels, C.M. Dobson, S. Linse, T.P.J. Knowles, D. Frenkel, Nature Physics 12 (2016) 874–880."},"quality_controlled":"1","scopus_import":"1","_id":"10378","author":[{"orcid":"0000-0002-7854-2139","last_name":"Šarić","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","first_name":"Anđela","full_name":"Šarić, Anđela"},{"last_name":"Buell","first_name":"Alexander K.","full_name":"Buell, Alexander K."},{"last_name":"Meisl","first_name":"Georg","full_name":"Meisl, Georg"},{"full_name":"Michaels, Thomas C. T.","last_name":"Michaels","first_name":"Thomas C. T."},{"last_name":"Dobson","first_name":"Christopher M.","full_name":"Dobson, Christopher M."},{"full_name":"Linse, Sara","last_name":"Linse","first_name":"Sara"},{"full_name":"Knowles, Tuomas P. J.","first_name":"Tuomas P. J.","last_name":"Knowles"},{"first_name":"Daan","last_name":"Frenkel","full_name":"Frenkel, Daan"}],"publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"article_processing_charge":"No","date_created":"2021-11-29T10:36:11Z","acknowledgement":"We acknowledge support from the Human Frontier Science Program and Emmanuel College (A.Š.), the Leverhulme Trust and Magdalene College (A.K.B.), St John’s College (T.C.T.M.), the Biotechnology and Biological Sciences Research Council (T.P.J.K. and C.M.D.), the Frances and Augustus Newman Foundation (T.P.J.K.), the European Research Council (T.P.J.K., T.C.T.M., S.L. and D.F.), and the Engineering and Physical Sciences Research Council (D.F.).","page":"874-880","publication":"Nature Physics","year":"2016","volume":12,"title":"Physical determinants of the self-replication of protein fibrils","external_id":{"pmid":["31031819"]},"article_type":"original"}]