---
_id: '9060'
abstract:
- lang: eng
  text: Molecular motors are essential to the living, generating fluctuations that
    boost transport and assist assembly. Active colloids, that consume energy to move,
    hold similar potential for man-made materials controlled by forces generated from
    within. Yet, their use as a powerhouse in materials science lacks. Here we show
    a massive acceleration of the annealing of a monolayer of passive beads by moderate
    addition of self-propelled microparticles. We rationalize our observations with
    a model of collisions that drive active fluctuations and activate the annealing.
    The experiment is quantitatively compared with Brownian dynamic simulations that
    further unveil a dynamical transition in the mechanism of annealing. Active dopants
    travel uniformly in the system or co-localize at the grain boundaries as a result
    of the persistence of their motion. Our findings uncover the potential of internal
    activity to control materials and lay the groundwork for the rise of materials
    science beyond equilibrium.
article_number: '3380'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sophie
  full_name: Ramananarivo, Sophie
  last_name: Ramananarivo
- first_name: Etienne
  full_name: Ducrot, Etienne
  last_name: Ducrot
- first_name: Jérémie A
  full_name: Palacci, Jérémie A
  id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
  last_name: Palacci
  orcid: 0000-0002-7253-9465
citation:
  ama: Ramananarivo S, Ducrot E, Palacci JA. Activity-controlled annealing of colloidal
    monolayers. <i>Nature Communications</i>. 2019;10(1). doi:<a href="https://doi.org/10.1038/s41467-019-11362-y">10.1038/s41467-019-11362-y</a>
  apa: Ramananarivo, S., Ducrot, E., &#38; Palacci, J. A. (2019). Activity-controlled
    annealing of colloidal monolayers. <i>Nature Communications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41467-019-11362-y">https://doi.org/10.1038/s41467-019-11362-y</a>
  chicago: Ramananarivo, Sophie, Etienne Ducrot, and Jérémie A Palacci. “Activity-Controlled
    Annealing of Colloidal Monolayers.” <i>Nature Communications</i>. Springer Nature,
    2019. <a href="https://doi.org/10.1038/s41467-019-11362-y">https://doi.org/10.1038/s41467-019-11362-y</a>.
  ieee: S. Ramananarivo, E. Ducrot, and J. A. Palacci, “Activity-controlled annealing
    of colloidal monolayers,” <i>Nature Communications</i>, vol. 10, no. 1. Springer
    Nature, 2019.
  ista: Ramananarivo S, Ducrot E, Palacci JA. 2019. Activity-controlled annealing
    of colloidal monolayers. Nature Communications. 10(1), 3380.
  mla: Ramananarivo, Sophie, et al. “Activity-Controlled Annealing of Colloidal Monolayers.”
    <i>Nature Communications</i>, vol. 10, no. 1, 3380, Springer Nature, 2019, doi:<a
    href="https://doi.org/10.1038/s41467-019-11362-y">10.1038/s41467-019-11362-y</a>.
  short: S. Ramananarivo, E. Ducrot, J.A. Palacci, Nature Communications 10 (2019).
date_created: 2021-02-02T13:43:36Z
date_published: 2019-07-29T00:00:00Z
date_updated: 2023-02-23T13:47:59Z
day: '29'
ddc:
- '530'
doi: 10.1038/s41467-019-11362-y
extern: '1'
external_id:
  arxiv:
  - '1909.07382'
  pmid:
  - '31358762'
file:
- access_level: open_access
  checksum: 70c6e5d6fbea0932b0669505ab6633ec
  content_type: application/pdf
  creator: cziletti
  date_created: 2021-02-02T13:47:21Z
  date_updated: 2021-02-02T13:47:21Z
  file_id: '9061'
  file_name: 2019_NatureComm_Ramananarivo.pdf
  file_size: 2820337
  relation: main_file
  success: 1
file_date_updated: 2021-02-02T13:47:21Z
has_accepted_license: '1'
intvolume: '        10'
issue: '1'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Activity-controlled annealing of colloidal monolayers
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 10
year: '2019'
...
---
_id: '13374'
abstract:
- lang: eng
  text: Confining molecules to volumes only slightly larger than the molecules themselves
    can profoundly alter their properties. Molecular switches—entities that can be
    toggled between two or more forms upon exposure to an external stimulus—often
    require conformational freedom to isomerize. Therefore, placing these switches
    in confined spaces can render them non-operational. To preserve the switchability
    of these species under confinement, we work with a water-soluble coordination
    cage that is flexible enough to adapt its shape to the conformation of the encapsulated
    guest. We show that owing to its flexibility, the cage is not only capable of
    accommodating—and solubilizing in water—several light-responsive spiropyran-based
    molecular switches, but, more importantly, it also provides an environment suitable
    for the efficient, reversible photoisomerization of the bound guests. Our findings
    pave the way towards studying various molecular switching processes in confined
    environments.
article_number: '641'
article_processing_charge: No
article_type: original
author:
- first_name: Dipak
  full_name: Samanta, Dipak
  last_name: Samanta
- first_name: Daria
  full_name: Galaktionova, Daria
  last_name: Galaktionova
- first_name: Julius
  full_name: Gemen, Julius
  last_name: Gemen
- first_name: Linda J. W.
  full_name: Shimon, Linda J. W.
  last_name: Shimon
- first_name: Yael
  full_name: Diskin-Posner, Yael
  last_name: Diskin-Posner
- first_name: Liat
  full_name: Avram, Liat
  last_name: Avram
- first_name: Petr
  full_name: Král, Petr
  last_name: Král
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: Samanta D, Galaktionova D, Gemen J, et al. Reversible chromism of spiropyran
    in the cavity of a flexible coordination cage. <i>Nature Communications</i>. 2018;9.
    doi:<a href="https://doi.org/10.1038/s41467-017-02715-6">10.1038/s41467-017-02715-6</a>
  apa: Samanta, D., Galaktionova, D., Gemen, J., Shimon, L. J. W., Diskin-Posner,
    Y., Avram, L., … Klajn, R. (2018). Reversible chromism of spiropyran in the cavity
    of a flexible coordination cage. <i>Nature Communications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41467-017-02715-6">https://doi.org/10.1038/s41467-017-02715-6</a>
  chicago: Samanta, Dipak, Daria Galaktionova, Julius Gemen, Linda J. W. Shimon, Yael
    Diskin-Posner, Liat Avram, Petr Král, and Rafal Klajn. “Reversible Chromism of
    Spiropyran in the Cavity of a Flexible Coordination Cage.” <i>Nature Communications</i>.
    Springer Nature, 2018. <a href="https://doi.org/10.1038/s41467-017-02715-6">https://doi.org/10.1038/s41467-017-02715-6</a>.
  ieee: D. Samanta <i>et al.</i>, “Reversible chromism of spiropyran in the cavity
    of a flexible coordination cage,” <i>Nature Communications</i>, vol. 9. Springer
    Nature, 2018.
  ista: Samanta D, Galaktionova D, Gemen J, Shimon LJW, Diskin-Posner Y, Avram L,
    Král P, Klajn R. 2018. Reversible chromism of spiropyran in the cavity of a flexible
    coordination cage. Nature Communications. 9, 641.
  mla: Samanta, Dipak, et al. “Reversible Chromism of Spiropyran in the Cavity of
    a Flexible Coordination Cage.” <i>Nature Communications</i>, vol. 9, 641, Springer
    Nature, 2018, doi:<a href="https://doi.org/10.1038/s41467-017-02715-6">10.1038/s41467-017-02715-6</a>.
  short: D. Samanta, D. Galaktionova, J. Gemen, L.J.W. Shimon, Y. Diskin-Posner, L.
    Avram, P. Král, R. Klajn, Nature Communications 9 (2018).
date_created: 2023-08-01T09:39:32Z
date_published: 2018-02-13T00:00:00Z
date_updated: 2024-10-14T12:14:34Z
day: '13'
doi: 10.1038/s41467-017-02715-6
extern: '1'
external_id:
  pmid:
  - '29440687'
intvolume: '         9'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41467-017-02715-6
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1038/s41467-018-03701-2
scopus_import: '1'
status: public
title: Reversible chromism of spiropyran in the cavity of a flexible coordination
  cage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '14003'
abstract:
- lang: eng
  text: "Molecular chirality plays an essential role in most biochemical processes.
    The observation and quantification of chirality-sensitive signals, however, remains
    extremely challenging, especially on ultrafast timescales and in dilute media.
    Here, we describe the experimental realization of an all-optical and ultrafast
    scheme for detecting chiral dynamics in molecules. This technique is based on
    high-harmonic generation by a combination of two-color counterrotating femtosecond
    laser pulses with polarization states tunable from linear to circular. We demonstrate
    two different implementations of chiral-sensitive high-harmonic spectroscopy on
    an ensemble of randomly oriented methyloxirane molecules in the gas phase. Using
    two elliptically polarized fields, we observe that the ellipticities maximizing
    the harmonic signal reach up to \r\n4.4\r\n±\r\n0.2\r\n%\r\n (at 17.6 eV). Using
    two circularly polarized fields, we observe circular dichroisms ranging up to
    \r\n13\r\n±\r\n6\r\n%\r\n (28.3–33.1 eV). Our theoretical analysis confirms that
    the observed chiral response originates from subfemtosecond electron dynamics
    driven by the magnetic component of the driving laser field. This assignment is
    supported by the experimental observation of a strong intensity dependence of
    the chiral effects and its agreement with theory. We moreover report and explain
    a pronounced variation of the signal strength and dichroism with the driving-field
    ellipticities and harmonic orders. Finally, we demonstrate the sensitivity of
    the experimental observables to the shape of the electron hole. This technique
    for chiral discrimination will yield femtosecond temporal resolution when integrated
    in a pump-probe scheme and subfemtosecond resolution on chiral charge migration
    in a self-probing scheme."
article_number: '031060'
article_processing_charge: No
article_type: original
author:
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Baykusheva DR, Wörner HJ. Chiral discrimination through bielliptical high-harmonic
    spectroscopy. <i>Physical Review X</i>. 2018;8(3). doi:<a href="https://doi.org/10.1103/physrevx.8.031060">10.1103/physrevx.8.031060</a>
  apa: Baykusheva, D. R., &#38; Wörner, H. J. (2018). Chiral discrimination through
    bielliptical high-harmonic spectroscopy. <i>Physical Review X</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevx.8.031060">https://doi.org/10.1103/physrevx.8.031060</a>
  chicago: Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Chiral Discrimination
    through Bielliptical High-Harmonic Spectroscopy.” <i>Physical Review X</i>. American
    Physical Society, 2018. <a href="https://doi.org/10.1103/physrevx.8.031060">https://doi.org/10.1103/physrevx.8.031060</a>.
  ieee: D. R. Baykusheva and H. J. Wörner, “Chiral discrimination through bielliptical
    high-harmonic spectroscopy,” <i>Physical Review X</i>, vol. 8, no. 3. American
    Physical Society, 2018.
  ista: Baykusheva DR, Wörner HJ. 2018. Chiral discrimination through bielliptical
    high-harmonic spectroscopy. Physical Review X. 8(3), 031060.
  mla: Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Chiral Discrimination
    through Bielliptical High-Harmonic Spectroscopy.” <i>Physical Review X</i>, vol.
    8, no. 3, 031060, American Physical Society, 2018, doi:<a href="https://doi.org/10.1103/physrevx.8.031060">10.1103/physrevx.8.031060</a>.
  short: D.R. Baykusheva, H.J. Wörner, Physical Review X 8 (2018).
date_created: 2023-08-10T06:34:48Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2023-08-22T07:42:07Z
day: '01'
doi: 10.1103/physrevx.8.031060
extern: '1'
intvolume: '         8'
issue: '3'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1103/PhysRevX.8.031060
month: '07'
oa: 1
oa_version: Published Version
publication: Physical Review X
publication_identifier:
  eissn:
  - 2160-3308
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chiral discrimination through bielliptical high-harmonic spectroscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2018'
...
---
_id: '14284'
abstract:
- lang: eng
  text: Pore-forming toxins (PFT) are virulence factors that transform from soluble
    to membrane-bound states. The Yersinia YaxAB system represents a family of binary
    α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures.
    YaxAB was shown to be cytotoxic and likely involved in pathogenesis, though the
    molecular basis for its two-component lytic mechanism remains elusive. Here, we
    present crystal structures of YaxA and YaxB, together with a cryo-electron microscopy
    map of the YaxAB complex. Our structures reveal a pore predominantly composed
    of decamers of YaxA–YaxB heterodimers. Both subunits bear membrane-active moieties,
    but only YaxA is capable of binding to membranes by itself. YaxB can subsequently
    be recruited to membrane-associated YaxA and induced to present its lytic transmembrane
    helices. Pore formation can progress by further oligomerization of YaxA–YaxB dimers.
    Our results allow for a comparison between pore assemblies belonging to the wider
    ClyA-like family of α-PFTs, highlighting diverse pore architectures.
article_number: '1806'
article_processing_charge: No
article_type: original
author:
- first_name: Bastian
  full_name: Bräuning, Bastian
  last_name: Bräuning
- first_name: Eva
  full_name: Bertosin, Eva
  last_name: Bertosin
- first_name: Florian M
  full_name: Praetorius, Florian M
  id: dfec9381-4341-11ee-8fd8-faa02bba7d62
  last_name: Praetorius
- first_name: Christian
  full_name: Ihling, Christian
  last_name: Ihling
- first_name: Alexandra
  full_name: Schatt, Alexandra
  last_name: Schatt
- first_name: Agnes
  full_name: Adler, Agnes
  last_name: Adler
- first_name: Klaus
  full_name: Richter, Klaus
  last_name: Richter
- first_name: Andrea
  full_name: Sinz, Andrea
  last_name: Sinz
- first_name: Hendrik
  full_name: Dietz, Hendrik
  last_name: Dietz
- first_name: Michael
  full_name: Groll, Michael
  last_name: Groll
citation:
  ama: Bräuning B, Bertosin E, Praetorius FM, et al. Structure and mechanism of the
    two-component α-helical pore-forming toxin YaxAB. <i>Nature Communications</i>.
    2018;9. doi:<a href="https://doi.org/10.1038/s41467-018-04139-2">10.1038/s41467-018-04139-2</a>
  apa: Bräuning, B., Bertosin, E., Praetorius, F. M., Ihling, C., Schatt, A., Adler,
    A., … Groll, M. (2018). Structure and mechanism of the two-component α-helical
    pore-forming toxin YaxAB. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-018-04139-2">https://doi.org/10.1038/s41467-018-04139-2</a>
  chicago: Bräuning, Bastian, Eva Bertosin, Florian M Praetorius, Christian Ihling,
    Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, and
    Michael Groll. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming
    Toxin YaxAB.” <i>Nature Communications</i>. Springer Nature, 2018. <a href="https://doi.org/10.1038/s41467-018-04139-2">https://doi.org/10.1038/s41467-018-04139-2</a>.
  ieee: B. Bräuning <i>et al.</i>, “Structure and mechanism of the two-component α-helical
    pore-forming toxin YaxAB,” <i>Nature Communications</i>, vol. 9. Springer Nature,
    2018.
  ista: Bräuning B, Bertosin E, Praetorius FM, Ihling C, Schatt A, Adler A, Richter
    K, Sinz A, Dietz H, Groll M. 2018. Structure and mechanism of the two-component
    α-helical pore-forming toxin YaxAB. Nature Communications. 9, 1806.
  mla: Bräuning, Bastian, et al. “Structure and Mechanism of the Two-Component α-Helical
    Pore-Forming Toxin YaxAB.” <i>Nature Communications</i>, vol. 9, 1806, Springer
    Nature, 2018, doi:<a href="https://doi.org/10.1038/s41467-018-04139-2">10.1038/s41467-018-04139-2</a>.
  short: B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler,
    K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).
date_created: 2023-09-06T12:07:33Z
date_published: 2018-05-04T00:00:00Z
date_updated: 2023-11-07T11:46:12Z
day: '04'
doi: 10.1038/s41467-018-04139-2
extern: '1'
external_id:
  pmid:
  - '29728606'
intvolume: '         9'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41467-018-04139-2
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '15232'
abstract:
- lang: eng
  text: 'In this paper we describe the potential of the enhanced X-ray Timing and
    Polarimetry (eXTP) mission for studies related to accretion flows in the strong
    field gravity regime around both stellar-mass and supermassive black-holes. eXTP
    has the unique capability of using advanced “spectral-timing-polarimetry” techniques
    to analyze the rapid variations with three orthogonal diagnostics of the flow
    and its geometry, yielding unprecedented insight into the inner accreting regions,
    the effects of strong field gravity on the material within them and the powerful
    outflows which are driven by the accretion process. '
article_number: '29504'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alessandra De
  full_name: Rosa, Alessandra De
  last_name: Rosa
- first_name: Phil
  full_name: Uttley, Phil
  last_name: Uttley
- first_name: LiJun
  full_name: Gou, LiJun
  last_name: Gou
- first_name: Yuan
  full_name: Liu, Yuan
  last_name: Liu
- first_name: Cosimo
  full_name: Bambi, Cosimo
  last_name: Bambi
- first_name: Didier
  full_name: Barret, Didier
  last_name: Barret
- first_name: Tomaso
  full_name: Belloni, Tomaso
  last_name: Belloni
- first_name: Emanuele
  full_name: Berti, Emanuele
  last_name: Berti
- first_name: Stefano
  full_name: Bianchi, Stefano
  last_name: Bianchi
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Piergiorgio
  full_name: Casella, Piergiorgio
  last_name: Casella
- first_name: Marco
  full_name: Feroci, Marco
  last_name: Feroci
- first_name: Valeria
  full_name: Ferrari, Valeria
  last_name: Ferrari
- first_name: Leonardo
  full_name: Gualtieri, Leonardo
  last_name: Gualtieri
- first_name: Jeremy
  full_name: Heyl, Jeremy
  last_name: Heyl
- first_name: Adam
  full_name: Ingram, Adam
  last_name: Ingram
- first_name: Vladimir
  full_name: Karas, Vladimir
  last_name: Karas
- first_name: FangJun
  full_name: Lu, FangJun
  last_name: Lu
- first_name: Bin
  full_name: Luo, Bin
  last_name: Luo
- first_name: Giorgio
  full_name: Matt, Giorgio
  last_name: Matt
- first_name: Sara
  full_name: Motta, Sara
  last_name: Motta
- first_name: Joseph
  full_name: Neilsen, Joseph
  last_name: Neilsen
- first_name: Paolo
  full_name: Pani, Paolo
  last_name: Pani
- first_name: Andrea
  full_name: Santangelo, Andrea
  last_name: Santangelo
- first_name: XinWen
  full_name: Shu, XinWen
  last_name: Shu
- first_name: JunFeng
  full_name: Wang, JunFeng
  last_name: Wang
- first_name: Jian-Min
  full_name: Wang, Jian-Min
  last_name: Wang
- first_name: YongQuan
  full_name: Xue, YongQuan
  last_name: Xue
- first_name: YuPeng
  full_name: Xu, YuPeng
  last_name: Xu
- first_name: WeiMin
  full_name: Yuan, WeiMin
  last_name: Yuan
- first_name: YeFei
  full_name: Yuan, YeFei
  last_name: Yuan
- first_name: Shuang-Nan
  full_name: Zhang, Shuang-Nan
  last_name: Zhang
- first_name: Shu
  full_name: Zhang, Shu
  last_name: Zhang
- first_name: Ivan
  full_name: Agudo, Ivan
  last_name: Agudo
- first_name: Lorenzo
  full_name: Amati, Lorenzo
  last_name: Amati
- first_name: Nils
  full_name: Andersson, Nils
  last_name: Andersson
- first_name: Cristina
  full_name: Baglio, Cristina
  last_name: Baglio
- first_name: Pavel
  full_name: Bakala, Pavel
  last_name: Bakala
- first_name: Altan
  full_name: Baykal, Altan
  last_name: Baykal
- first_name: Sudip
  full_name: Bhattacharyya, Sudip
  last_name: Bhattacharyya
- first_name: Ignazio
  full_name: Bombaci, Ignazio
  last_name: Bombaci
- first_name: Niccoló
  full_name: Bucciantini, Niccoló
  last_name: Bucciantini
- first_name: Fiamma
  full_name: Capitanio, Fiamma
  last_name: Capitanio
- first_name: Riccardo
  full_name: Ciolfi, Riccardo
  last_name: Ciolfi
- first_name: Wei K.
  full_name: Cui, Wei K.
  last_name: Cui
- first_name: Filippo
  full_name: D’Ammando, Filippo
  last_name: D’Ammando
- first_name: Thomas
  full_name: Dauser, Thomas
  last_name: Dauser
- first_name: Melania
  full_name: Del Santo, Melania
  last_name: Del Santo
- first_name: Barbara
  full_name: De Marco, Barbara
  last_name: De Marco
- first_name: Tiziana
  full_name: Di Salvo, Tiziana
  last_name: Di Salvo
- first_name: Chris
  full_name: Done, Chris
  last_name: Done
- first_name: Michal
  full_name: Dovčiak, Michal
  last_name: Dovčiak
- first_name: Andrew C.
  full_name: Fabian, Andrew C.
  last_name: Fabian
- first_name: Maurizio
  full_name: Falanga, Maurizio
  last_name: Falanga
- first_name: Angelo Francesco
  full_name: Gambino, Angelo Francesco
  last_name: Gambino
- first_name: Bruce
  full_name: Gendre, Bruce
  last_name: Gendre
- first_name: Victoria
  full_name: Grinberg, Victoria
  last_name: Grinberg
- first_name: Alexander
  full_name: Heger, Alexander
  last_name: Heger
- first_name: Jeroen
  full_name: Homan, Jeroen
  last_name: Homan
- first_name: Rosario
  full_name: Iaria, Rosario
  last_name: Iaria
- first_name: JiaChen
  full_name: Jiang, JiaChen
  last_name: Jiang
- first_name: ChiChuan
  full_name: Jin, ChiChuan
  last_name: Jin
- first_name: Elmar
  full_name: Koerding, Elmar
  last_name: Koerding
- first_name: Manu
  full_name: Linares, Manu
  last_name: Linares
- first_name: Zhu
  full_name: Liu, Zhu
  last_name: Liu
- first_name: Thomas J.
  full_name: Maccarone, Thomas J.
  last_name: Maccarone
- first_name: Julien
  full_name: Malzac, Julien
  last_name: Malzac
- first_name: Antonios
  full_name: Manousakis, Antonios
  last_name: Manousakis
- first_name: Frédéric
  full_name: Marin, Frédéric
  last_name: Marin
- first_name: Andrea
  full_name: Marinucci, Andrea
  last_name: Marinucci
- first_name: Missagh
  full_name: Mehdipour, Missagh
  last_name: Mehdipour
- first_name: Mariano
  full_name: Méndez, Mariano
  last_name: Méndez
- first_name: Simone
  full_name: Migliari, Simone
  last_name: Migliari
- first_name: Cole
  full_name: Miller, Cole
  last_name: Miller
- first_name: Giovanni
  full_name: Miniutti, Giovanni
  last_name: Miniutti
- first_name: Emanuele
  full_name: Nardini, Emanuele
  last_name: Nardini
- first_name: Paul T.
  full_name: O’Brien, Paul T.
  last_name: O’Brien
- first_name: Julian P.
  full_name: Osborne, Julian P.
  last_name: Osborne
- first_name: Pierre Olivier
  full_name: Petrucci, Pierre Olivier
  last_name: Petrucci
- first_name: Andrea
  full_name: Possenti, Andrea
  last_name: Possenti
- first_name: Alessandro
  full_name: Riggio, Alessandro
  last_name: Riggio
- first_name: Jerome
  full_name: Rodriguez, Jerome
  last_name: Rodriguez
- first_name: Andrea
  full_name: Sanna, Andrea
  last_name: Sanna
- first_name: LiJing
  full_name: Shao, LiJing
  last_name: Shao
- first_name: Malgosia
  full_name: Sobolewska, Malgosia
  last_name: Sobolewska
- first_name: Eva
  full_name: Sramkova, Eva
  last_name: Sramkova
- first_name: Abigail L.
  full_name: Stevens, Abigail L.
  last_name: Stevens
- first_name: Holger
  full_name: Stiele, Holger
  last_name: Stiele
- first_name: Giulia
  full_name: Stratta, Giulia
  last_name: Stratta
- first_name: Zdenek
  full_name: Stuchlik, Zdenek
  last_name: Stuchlik
- first_name: Jiri
  full_name: Svoboda, Jiri
  last_name: Svoboda
- first_name: Fabrizio
  full_name: Tamburini, Fabrizio
  last_name: Tamburini
- first_name: Thomas M.
  full_name: Tauris, Thomas M.
  last_name: Tauris
- first_name: Francesco
  full_name: Tombesi, Francesco
  last_name: Tombesi
- first_name: Gabriel
  full_name: Torok, Gabriel
  last_name: Torok
- first_name: Martin
  full_name: Urbanec, Martin
  last_name: Urbanec
- first_name: Frederic
  full_name: Vincent, Frederic
  last_name: Vincent
- first_name: QingWen
  full_name: Wu, QingWen
  last_name: Wu
- first_name: Feng
  full_name: Yuan, Feng
  last_name: Yuan
- first_name: Jean J. M.
  full_name: in’ t Zand, Jean J. M.
  last_name: in’ t Zand
- first_name: Andrzej A.
  full_name: Zdziarski, Andrzej A.
  last_name: Zdziarski
- first_name: XinLin
  full_name: Zhou, XinLin
  last_name: Zhou
citation:
  ama: Rosa AD, Uttley P, Gou L, et al. Accretion in strong field gravity with eXTP.
    <i>Science China Physics, Mechanics &#38; Astronomy</i>. 2018;62(2). doi:<a href="https://doi.org/10.1007/s11433-018-9297-0">10.1007/s11433-018-9297-0</a>
  apa: Rosa, A. D., Uttley, P., Gou, L., Liu, Y., Bambi, C., Barret, D., … Zhou, X.
    (2018). Accretion in strong field gravity with eXTP. <i>Science China Physics,
    Mechanics &#38; Astronomy</i>. Springer Nature. <a href="https://doi.org/10.1007/s11433-018-9297-0">https://doi.org/10.1007/s11433-018-9297-0</a>
  chicago: Rosa, Alessandra De, Phil Uttley, LiJun Gou, Yuan Liu, Cosimo Bambi, Didier
    Barret, Tomaso Belloni, et al. “Accretion in Strong Field Gravity with EXTP.”
    <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature, 2018.
    <a href="https://doi.org/10.1007/s11433-018-9297-0">https://doi.org/10.1007/s11433-018-9297-0</a>.
  ieee: A. D. Rosa <i>et al.</i>, “Accretion in strong field gravity with eXTP,” <i>Science
    China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2. Springer Nature,
    2018.
  ista: Rosa AD et al. 2018. Accretion in strong field gravity with eXTP. Science
    China Physics, Mechanics &#38; Astronomy. 62(2), 29504.
  mla: Rosa, Alessandra De, et al. “Accretion in Strong Field Gravity with EXTP.”
    <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2, 29504,
    Springer Nature, 2018, doi:<a href="https://doi.org/10.1007/s11433-018-9297-0">10.1007/s11433-018-9297-0</a>.
  short: A.D. Rosa, P. Uttley, L. Gou, Y. Liu, C. Bambi, D. Barret, T. Belloni, E.
    Berti, S. Bianchi, I. Caiazzo, P. Casella, M. Feroci, V. Ferrari, L. Gualtieri,
    J. Heyl, A. Ingram, V. Karas, F. Lu, B. Luo, G. Matt, S. Motta, J. Neilsen, P.
    Pani, A. Santangelo, X. Shu, J. Wang, J.-M. Wang, Y. Xue, Y. Xu, W. Yuan, Y. Yuan,
    S.-N. Zhang, S. Zhang, I. Agudo, L. Amati, N. Andersson, C. Baglio, P. Bakala,
    A. Baykal, S. Bhattacharyya, I. Bombaci, N. Bucciantini, F. Capitanio, R. Ciolfi,
    W.K. Cui, F. D’Ammando, T. Dauser, M. Del Santo, B. De Marco, T. Di Salvo, C.
    Done, M. Dovčiak, A.C. Fabian, M. Falanga, A.F. Gambino, B. Gendre, V. Grinberg,
    A. Heger, J. Homan, R. Iaria, J. Jiang, C. Jin, E. Koerding, M. Linares, Z. Liu,
    T.J. Maccarone, J. Malzac, A. Manousakis, F. Marin, A. Marinucci, M. Mehdipour,
    M. Méndez, S. Migliari, C. Miller, G. Miniutti, E. Nardini, P.T. O’Brien, J.P.
    Osborne, P.O. Petrucci, A. Possenti, A. Riggio, J. Rodriguez, A. Sanna, L. Shao,
    M. Sobolewska, E. Sramkova, A.L. Stevens, H. Stiele, G. Stratta, Z. Stuchlik,
    J. Svoboda, F. Tamburini, T.M. Tauris, F. Tombesi, G. Torok, M. Urbanec, F. Vincent,
    Q. Wu, F. Yuan, J.J.M. in’ t Zand, A.A. Zdziarski, X. Zhou, Science China Physics,
    Mechanics &#38; Astronomy 62 (2018).
date_created: 2024-03-26T10:37:41Z
date_published: 2018-12-07T00:00:00Z
date_updated: 2024-04-05T07:12:09Z
day: '07'
doi: 10.1007/s11433-018-9297-0
extern: '1'
external_id:
  arxiv:
  - '1812.04022'
intvolume: '        62'
issue: '2'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1812.04022
month: '12'
oa: 1
oa_version: Preprint
publication: Science China Physics, Mechanics & Astronomy
publication_identifier:
  eissn:
  - 1869-1927
  issn:
  - 1674-7348
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Accretion in strong field gravity with eXTP
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 62
year: '2018'
...
---
_id: '15233'
abstract:
- lang: eng
  text: In this paper we present the science potential of the enhanced X-ray Timing
    and Polarimetry (eXTP) mission for studies of strongly magnetized objects. We
    will focus on the physics and astrophysics of strongly magnetized objects, namely
    magnetars, accreting X-ray pulsars, and rotation powered pulsars. We also discuss
    the science potential of eXTP for QED studies. Developed by an international Consortium
    led by the Institute of High Energy Physics of the Chinese Academy of Sciences,
    the eXTP mission is expected to be launched in the mid 2020s.
article_number: '29505'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Andrea
  full_name: Santangelo, Andrea
  last_name: Santangelo
- first_name: Silvia
  full_name: Zane, Silvia
  last_name: Zane
- first_name: Hua
  full_name: Feng, Hua
  last_name: Feng
- first_name: RenXin
  full_name: Xu, RenXin
  last_name: Xu
- first_name: Victor
  full_name: Doroshenko, Victor
  last_name: Doroshenko
- first_name: Enrico
  full_name: Bozzo, Enrico
  last_name: Bozzo
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: Francesco Coti
  full_name: Zelati, Francesco Coti
  last_name: Zelati
- first_name: Paolo
  full_name: Esposito, Paolo
  last_name: Esposito
- first_name: Denis
  full_name: González-Caniulef, Denis
  last_name: González-Caniulef
- first_name: Jeremy
  full_name: Heyl, Jeremy
  last_name: Heyl
- first_name: Daniela
  full_name: Huppenkothen, Daniela
  last_name: Huppenkothen
- first_name: Gianluca
  full_name: Israel, Gianluca
  last_name: Israel
- first_name: ZhaoSheng
  full_name: Li, ZhaoSheng
  last_name: Li
- first_name: Lin
  full_name: Lin, Lin
  last_name: Lin
- first_name: Roberto
  full_name: Mignani, Roberto
  last_name: Mignani
- first_name: Nanda
  full_name: Rea, Nanda
  last_name: Rea
- first_name: Mauro
  full_name: Orlandini, Mauro
  last_name: Orlandini
- first_name: Roberto
  full_name: Taverna, Roberto
  last_name: Taverna
- first_name: Hao
  full_name: Tong, Hao
  last_name: Tong
- first_name: Roberto
  full_name: Turolla, Roberto
  last_name: Turolla
- first_name: Cristina
  full_name: Baglio, Cristina
  last_name: Baglio
- first_name: Federico
  full_name: Bernardini, Federico
  last_name: Bernardini
- first_name: Niccolo’
  full_name: Bucciantini, Niccolo’
  last_name: Bucciantini
- first_name: Marco
  full_name: Feroci, Marco
  last_name: Feroci
- first_name: Felix
  full_name: Fürst, Felix
  last_name: Fürst
- first_name: Ersin
  full_name: Göğüş, Ersin
  last_name: Göğüş
- first_name: Can
  full_name: Güngör, Can
  last_name: Güngör
- first_name: Long
  full_name: Ji, Long
  last_name: Ji
- first_name: FangJun
  full_name: Lu, FangJun
  last_name: Lu
- first_name: Antonios
  full_name: Manousakis, Antonios
  last_name: Manousakis
- first_name: Sandro
  full_name: Mereghetti, Sandro
  last_name: Mereghetti
- first_name: Romana
  full_name: Mikusincova, Romana
  last_name: Mikusincova
- first_name: Biswajit
  full_name: Paul, Biswajit
  last_name: Paul
- first_name: Chanda
  full_name: Prescod-Weinstein, Chanda
  last_name: Prescod-Weinstein
- first_name: George
  full_name: Younes, George
  last_name: Younes
- first_name: Andrea
  full_name: Tiengo, Andrea
  last_name: Tiengo
- first_name: YuPeng
  full_name: Xu, YuPeng
  last_name: Xu
- first_name: Anna
  full_name: Watts, Anna
  last_name: Watts
- first_name: Shu
  full_name: Zhang, Shu
  last_name: Zhang
- first_name: Shuang-Nan
  full_name: Zhan, Shuang-Nan
  last_name: Zhan
citation:
  ama: Santangelo A, Zane S, Feng H, et al. Physics and astrophysics of strong magnetic
    field systems with eXTP. <i>Science China Physics, Mechanics &#38; Astronomy</i>.
    2018;62(2). doi:<a href="https://doi.org/10.1007/s11433-018-9234-3">10.1007/s11433-018-9234-3</a>
  apa: Santangelo, A., Zane, S., Feng, H., Xu, R., Doroshenko, V., Bozzo, E., … Zhan,
    S.-N. (2018). Physics and astrophysics of strong magnetic field systems with eXTP.
    <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature. <a href="https://doi.org/10.1007/s11433-018-9234-3">https://doi.org/10.1007/s11433-018-9234-3</a>
  chicago: Santangelo, Andrea, Silvia Zane, Hua Feng, RenXin Xu, Victor Doroshenko,
    Enrico Bozzo, Ilaria Caiazzo, et al. “Physics and Astrophysics of Strong Magnetic
    Field Systems with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>.
    Springer Nature, 2018. <a href="https://doi.org/10.1007/s11433-018-9234-3">https://doi.org/10.1007/s11433-018-9234-3</a>.
  ieee: A. Santangelo <i>et al.</i>, “Physics and astrophysics of strong magnetic
    field systems with eXTP,” <i>Science China Physics, Mechanics &#38; Astronomy</i>,
    vol. 62, no. 2. Springer Nature, 2018.
  ista: Santangelo A, Zane S, Feng H, Xu R, Doroshenko V, Bozzo E, Caiazzo I, Zelati
    FC, Esposito P, González-Caniulef D, Heyl J, Huppenkothen D, Israel G, Li Z, Lin
    L, Mignani R, Rea N, Orlandini M, Taverna R, Tong H, Turolla R, Baglio C, Bernardini
    F, Bucciantini N, Feroci M, Fürst F, Göğüş E, Güngör C, Ji L, Lu F, Manousakis
    A, Mereghetti S, Mikusincova R, Paul B, Prescod-Weinstein C, Younes G, Tiengo
    A, Xu Y, Watts A, Zhang S, Zhan S-N. 2018. Physics and astrophysics of strong
    magnetic field systems with eXTP. Science China Physics, Mechanics &#38; Astronomy.
    62(2), 29505.
  mla: Santangelo, Andrea, et al. “Physics and Astrophysics of Strong Magnetic Field
    Systems with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol.
    62, no. 2, 29505, Springer Nature, 2018, doi:<a href="https://doi.org/10.1007/s11433-018-9234-3">10.1007/s11433-018-9234-3</a>.
  short: A. Santangelo, S. Zane, H. Feng, R. Xu, V. Doroshenko, E. Bozzo, I. Caiazzo,
    F.C. Zelati, P. Esposito, D. González-Caniulef, J. Heyl, D. Huppenkothen, G. Israel,
    Z. Li, L. Lin, R. Mignani, N. Rea, M. Orlandini, R. Taverna, H. Tong, R. Turolla,
    C. Baglio, F. Bernardini, N. Bucciantini, M. Feroci, F. Fürst, E. Göğüş, C. Güngör,
    L. Ji, F. Lu, A. Manousakis, S. Mereghetti, R. Mikusincova, B. Paul, C. Prescod-Weinstein,
    G. Younes, A. Tiengo, Y. Xu, A. Watts, S. Zhang, S.-N. Zhan, Science China Physics,
    Mechanics &#38; Astronomy 62 (2018).
date_created: 2024-03-26T10:38:05Z
date_published: 2018-10-08T00:00:00Z
date_updated: 2024-04-08T07:01:20Z
day: '08'
doi: 10.1007/s11433-018-9234-3
extern: '1'
external_id:
  arxiv:
  - '1812.04460'
intvolume: '        62'
issue: '2'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1812.04460
month: '10'
oa: 1
oa_version: Preprint
publication: Science China Physics, Mechanics & Astronomy
publication_identifier:
  eissn:
  - 1869-1927
  issn:
  - 1674-7348
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Physics and astrophysics of strong magnetic field systems with eXTP
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 62
year: '2018'
...
---
_id: '10626'
abstract:
- lang: eng
  text: "Owing to their wide tunability, multiple internal degrees of freedom, and
    low disorder, graphene heterostructures are emerging as a promising experimental
    platform for fractional quantum Hall (FQH) studies. Here, we report FQH thermal
    activation gap measurements in dual graphite-gated monolayer graphene devices
    fabricated in an edgeless Corbino geometry. In devices with substrate-induced
    sublattice splitting, we find a tunable crossover between single- and multicomponent
    FQH states in the zero energy Landau level. Activation gaps in the single-component
    regime show excellent agreement with numerical calculations using a single broadening
    parameter \r\nΓ≈7.2K. In the first excited Landau level, in contrast, FQH gaps
    are strongly influenced by Landau level mixing, and we observe an unexpected valley-ordered
    state at integer filling ν=−4."
acknowledgement: We thank Cory Dean, S. Chen, Y. Zeng, M. Yankowitz, and J. Li for
  discussing their unpublished data and for sharing the stack inversion technique.
  The authors acknowledge further discussions of the results with I. Sodemann, M.
  Zaletel, C. Nayak, and J. Jain. A. F. Y., H. P., H. Z., and E. M. S. were supported
  by the ARO under awards 69188PHH and MURI W911NF-17-1-0323. A portion of this work
  was performed at the National High Magnetic Field Laboratory, which is supported
  by National Science Foundation Cooperative Agreement No. DMR-1644779 and the State
  of Florida. K. W. and T. T. acknowledge support from the Elemental Strategy Initiative
  conducted by the MEXT, Japan, and JSPS KAKENHI Grant No. JP15K21722. E. M. S. acknowledges
  the support of the Elings Prize Fellowship in Science of the California Nanosystems
  Institute at the University of California, Santa Barbara. A. F. Y. acknowledges
  the support of the David and Lucile Packard Foundation.
article_number: '226801'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: H.
  full_name: Zhou, H.
  last_name: Zhou
- first_name: E. M.
  full_name: Spanton, E. M.
  last_name: Spanton
- first_name: T.
  full_name: Taniguchi, T.
  last_name: Taniguchi
- first_name: K.
  full_name: Watanabe, K.
  last_name: Watanabe
- first_name: A. F.
  full_name: Young, A. F.
  last_name: Young
citation:
  ama: Polshyn H, Zhou H, Spanton EM, Taniguchi T, Watanabe K, Young AF. Quantitative
    transport measurements of fractional quantum Hall energy gaps in edgeless graphene
    devices. <i>Physical Review Letters</i>. 2018;121(22). doi:<a href="https://doi.org/10.1103/physrevlett.121.226801">10.1103/physrevlett.121.226801</a>
  apa: Polshyn, H., Zhou, H., Spanton, E. M., Taniguchi, T., Watanabe, K., &#38; Young,
    A. F. (2018). Quantitative transport measurements of fractional quantum Hall energy
    gaps in edgeless graphene devices. <i>Physical Review Letters</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevlett.121.226801">https://doi.org/10.1103/physrevlett.121.226801</a>
  chicago: Polshyn, Hryhoriy, H. Zhou, E. M. Spanton, T. Taniguchi, K. Watanabe, and
    A. F. Young. “Quantitative Transport Measurements of Fractional Quantum Hall Energy
    Gaps in Edgeless Graphene Devices.” <i>Physical Review Letters</i>. American Physical
    Society, 2018. <a href="https://doi.org/10.1103/physrevlett.121.226801">https://doi.org/10.1103/physrevlett.121.226801</a>.
  ieee: H. Polshyn, H. Zhou, E. M. Spanton, T. Taniguchi, K. Watanabe, and A. F. Young,
    “Quantitative transport measurements of fractional quantum Hall energy gaps in
    edgeless graphene devices,” <i>Physical Review Letters</i>, vol. 121, no. 22.
    American Physical Society, 2018.
  ista: Polshyn H, Zhou H, Spanton EM, Taniguchi T, Watanabe K, Young AF. 2018. Quantitative
    transport measurements of fractional quantum Hall energy gaps in edgeless graphene
    devices. Physical Review Letters. 121(22), 226801.
  mla: Polshyn, Hryhoriy, et al. “Quantitative Transport Measurements of Fractional
    Quantum Hall Energy Gaps in Edgeless Graphene Devices.” <i>Physical Review Letters</i>,
    vol. 121, no. 22, 226801, American Physical Society, 2018, doi:<a href="https://doi.org/10.1103/physrevlett.121.226801">10.1103/physrevlett.121.226801</a>.
  short: H. Polshyn, H. Zhou, E.M. Spanton, T. Taniguchi, K. Watanabe, A.F. Young,
    Physical Review Letters 121 (2018).
date_created: 2022-01-14T12:15:47Z
date_published: 2018-11-28T00:00:00Z
date_updated: 2022-01-14T13:48:35Z
day: '28'
doi: 10.1103/physrevlett.121.226801
extern: '1'
external_id:
  arxiv:
  - '1805.04199'
intvolume: '       121'
issue: '22'
keyword:
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1805.04199
month: '11'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantitative transport measurements of fractional quantum Hall energy gaps
  in edgeless graphene devices
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 121
year: '2018'
...
---
_id: '10362'
abstract:
- lang: eng
  text: Nuclear pore complexes (NPCs) form gateways that control molecular exchange
    between the nucleus and the cytoplasm. They impose a diffusion barrier to macromolecules
    and enable the selective transport of nuclear transport receptors with bound cargo.
    The underlying mechanisms that establish these permeability properties remain
    to be fully elucidated but require unstructured nuclear pore proteins rich in
    Phe-Gly (FG)-repeat domains of different types, such as FxFG and GLFG. While physical
    modeling and in vitro approaches have provided a framework for explaining how
    the FG network contributes to the barrier and transport properties of the NPC,
    it remains unknown whether the number and/or the spatial positioning of different
    FG-domains along a cylindrical, ∼40 nm diameter transport channel contributes
    to their collective properties and function. To begin to answer these questions,
    we have used DNA origami to build a cylinder that mimics the dimensions of the
    central transport channel and can house a specified number of FG-domains at specific
    positions with easily tunable design parameters, such as grafting density and
    topology. We find the overall morphology of the FG-domain assemblies to be dependent
    on their chemical composition, determined by the type and density of FG-repeat,
    and on their architectural confinement provided by the DNA cylinder, largely consistent
    with here presented molecular dynamics simulations based on a coarse-grained polymer
    model. In addition, high-speed atomic force microscopy reveals local and reversible
    FG-domain condensation that transiently occludes the lumen of the DNA central
    channel mimics, suggestive of how the NPC might establish its permeability properties.
acknowledgement: We thank J. Edel and members of the Lusk, Lin and Hoogenboom lab
  for discussion and acknowledge A. Pyne and R. Thorogate for support carrying out
  the AFM experiments. This work was funded by the NIH (R21GM109466 to CPL, CL and
  TJM, DP2GM114830 to CL, RO1GM105672 to CPL, and T32GM007223 to PDEF) and the UK
  Engineering and Physical Sciences Research Council (EP/L015277/1, EP/L504889/1,
  and EP/M028100/1).
article_processing_charge: No
article_type: original
author:
- first_name: Patrick D. Ellis
  full_name: Fisher, Patrick D. Ellis
  last_name: Fisher
- first_name: Qi
  full_name: Shen, Qi
  last_name: Shen
- first_name: Bernice
  full_name: Akpinar, Bernice
  last_name: Akpinar
- first_name: Luke K.
  full_name: Davis, Luke K.
  last_name: Davis
- first_name: Kenny Kwok Hin
  full_name: Chung, Kenny Kwok Hin
  last_name: Chung
- first_name: David
  full_name: Baddeley, David
  last_name: Baddeley
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Thomas J.
  full_name: Melia, Thomas J.
  last_name: Melia
- first_name: Bart W.
  full_name: Hoogenboom, Bart W.
  last_name: Hoogenboom
- first_name: Chenxiang
  full_name: Lin, Chenxiang
  last_name: Lin
- first_name: C. Patrick
  full_name: Lusk, C. Patrick
  last_name: Lusk
citation:
  ama: Fisher PDE, Shen Q, Akpinar B, et al. A Programmable DNA origami platform for
    organizing intrinsically disordered nucleoporins within nanopore confinement.
    <i>ACS Nano</i>. 2018;12(2):1508-1518. doi:<a href="https://doi.org/10.1021/acsnano.7b08044">10.1021/acsnano.7b08044</a>
  apa: Fisher, P. D. E., Shen, Q., Akpinar, B., Davis, L. K., Chung, K. K. H., Baddeley,
    D., … Lusk, C. P. (2018). A Programmable DNA origami platform for organizing intrinsically
    disordered nucleoporins within nanopore confinement. <i>ACS Nano</i>. American
    Chemical Society. <a href="https://doi.org/10.1021/acsnano.7b08044">https://doi.org/10.1021/acsnano.7b08044</a>
  chicago: Fisher, Patrick D. Ellis, Qi Shen, Bernice Akpinar, Luke K. Davis, Kenny
    Kwok Hin Chung, David Baddeley, Anđela Šarić, et al. “A Programmable DNA Origami
    Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore
    Confinement.” <i>ACS Nano</i>. American Chemical Society, 2018. <a href="https://doi.org/10.1021/acsnano.7b08044">https://doi.org/10.1021/acsnano.7b08044</a>.
  ieee: P. D. E. Fisher <i>et al.</i>, “A Programmable DNA origami platform for organizing
    intrinsically disordered nucleoporins within nanopore confinement,” <i>ACS Nano</i>,
    vol. 12, no. 2. American Chemical Society, pp. 1508–1518, 2018.
  ista: Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia
    TJ, Hoogenboom BW, Lin C, Lusk CP. 2018. A Programmable DNA origami platform for
    organizing intrinsically disordered nucleoporins within nanopore confinement.
    ACS Nano. 12(2), 1508–1518.
  mla: Fisher, Patrick D. Ellis, et al. “A Programmable DNA Origami Platform for Organizing
    Intrinsically Disordered Nucleoporins within Nanopore Confinement.” <i>ACS Nano</i>,
    vol. 12, no. 2, American Chemical Society, 2018, pp. 1508–18, doi:<a href="https://doi.org/10.1021/acsnano.7b08044">10.1021/acsnano.7b08044</a>.
  short: P.D.E. Fisher, Q. Shen, B. Akpinar, L.K. Davis, K.K.H. Chung, D. Baddeley,
    A. Šarić, T.J. Melia, B.W. Hoogenboom, C. Lin, C.P. Lusk, ACS Nano 12 (2018) 1508–1518.
date_created: 2021-11-26T15:15:00Z
date_published: 2018-01-19T00:00:00Z
date_updated: 2021-11-26T15:57:02Z
day: '19'
doi: 10.1021/acsnano.7b08044
extern: '1'
external_id:
  pmid:
  - '29350911'
intvolume: '        12'
issue: '2'
keyword:
- general physics and astronomy
language:
- iso: eng
month: '01'
oa_version: None
page: 1508-1518
pmid: 1
publication: ACS Nano
publication_identifier:
  eissn:
  - 1936-086X
  issn:
  - 1936-0851
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A Programmable DNA origami platform for organizing intrinsically disordered
  nucleoporins within nanopore confinement
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 12
year: '2018'
...
---
_id: '8419'
abstract:
- lang: eng
  text: "In this survey, we provide a concise introduction to convex billiards and
    describe some recent results, obtained by the authors and collaborators, on the
    classification of integrable billiards, namely the so-called Birkhoff conjecture.\r\n\r\nThis
    article is part of the theme issue ‘Finite dimensional integrable systems: new
    trends and methods’."
article_number: '20170419'
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
- first_name: Alfonso
  full_name: Sorrentino, Alfonso
  last_name: Sorrentino
citation:
  ama: 'Kaloshin V, Sorrentino A. On the integrability of Birkhoff billiards. <i>Philosophical
    Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences</i>.
    2018;376(2131). doi:<a href="https://doi.org/10.1098/rsta.2017.0419">10.1098/rsta.2017.0419</a>'
  apa: 'Kaloshin, V., &#38; Sorrentino, A. (2018). On the integrability of Birkhoff
    billiards. <i>Philosophical Transactions of the Royal Society A: Mathematical,
    Physical and Engineering Sciences</i>. The Royal Society. <a href="https://doi.org/10.1098/rsta.2017.0419">https://doi.org/10.1098/rsta.2017.0419</a>'
  chicago: 'Kaloshin, Vadim, and Alfonso Sorrentino. “On the Integrability of Birkhoff
    Billiards.” <i>Philosophical Transactions of the Royal Society A: Mathematical,
    Physical and Engineering Sciences</i>. The Royal Society, 2018. <a href="https://doi.org/10.1098/rsta.2017.0419">https://doi.org/10.1098/rsta.2017.0419</a>.'
  ieee: 'V. Kaloshin and A. Sorrentino, “On the integrability of Birkhoff billiards,”
    <i>Philosophical Transactions of the Royal Society A: Mathematical, Physical and
    Engineering Sciences</i>, vol. 376, no. 2131. The Royal Society, 2018.'
  ista: 'Kaloshin V, Sorrentino A. 2018. On the integrability of Birkhoff billiards.
    Philosophical Transactions of the Royal Society A: Mathematical, Physical and
    Engineering Sciences. 376(2131), 20170419.'
  mla: 'Kaloshin, Vadim, and Alfonso Sorrentino. “On the Integrability of Birkhoff
    Billiards.” <i>Philosophical Transactions of the Royal Society A: Mathematical,
    Physical and Engineering Sciences</i>, vol. 376, no. 2131, 20170419, The Royal
    Society, 2018, doi:<a href="https://doi.org/10.1098/rsta.2017.0419">10.1098/rsta.2017.0419</a>.'
  short: 'V. Kaloshin, A. Sorrentino, Philosophical Transactions of the Royal Society
    A: Mathematical, Physical and Engineering Sciences 376 (2018).'
date_created: 2020-09-17T10:42:01Z
date_published: 2018-10-28T00:00:00Z
date_updated: 2021-01-12T08:19:09Z
day: '28'
doi: 10.1098/rsta.2017.0419
extern: '1'
intvolume: '       376'
issue: '2131'
keyword:
- General Engineering
- General Physics and Astronomy
- General Mathematics
language:
- iso: eng
month: '10'
oa_version: None
publication: 'Philosophical Transactions of the Royal Society A: Mathematical, Physical
  and Engineering Sciences'
publication_identifier:
  issn:
  - 1364-503X
  - 1471-2962
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
status: public
title: On the integrability of Birkhoff billiards
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 376
year: '2018'
...
---
_id: '8420'
abstract:
- lang: eng
  text: We show that in the space of all convex billiard boundaries, the set of boundaries
    with rational caustics is dense. More precisely, the set of billiard boundaries
    with caustics of rotation number 1/q is polynomially sense in the smooth case,
    and exponentially dense in the analytic case.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
- first_name: Ke
  full_name: Zhang, Ke
  last_name: Zhang
citation:
  ama: Kaloshin V, Zhang K. Density of convex billiards with rational caustics. <i>Nonlinearity</i>.
    2018;31(11):5214-5234. doi:<a href="https://doi.org/10.1088/1361-6544/aadc12">10.1088/1361-6544/aadc12</a>
  apa: Kaloshin, V., &#38; Zhang, K. (2018). Density of convex billiards with rational
    caustics. <i>Nonlinearity</i>. IOP Publishing. <a href="https://doi.org/10.1088/1361-6544/aadc12">https://doi.org/10.1088/1361-6544/aadc12</a>
  chicago: Kaloshin, Vadim, and Ke Zhang. “Density of Convex Billiards with Rational
    Caustics.” <i>Nonlinearity</i>. IOP Publishing, 2018. <a href="https://doi.org/10.1088/1361-6544/aadc12">https://doi.org/10.1088/1361-6544/aadc12</a>.
  ieee: V. Kaloshin and K. Zhang, “Density of convex billiards with rational caustics,”
    <i>Nonlinearity</i>, vol. 31, no. 11. IOP Publishing, pp. 5214–5234, 2018.
  ista: Kaloshin V, Zhang K. 2018. Density of convex billiards with rational caustics.
    Nonlinearity. 31(11), 5214–5234.
  mla: Kaloshin, Vadim, and Ke Zhang. “Density of Convex Billiards with Rational Caustics.”
    <i>Nonlinearity</i>, vol. 31, no. 11, IOP Publishing, 2018, pp. 5214–34, doi:<a
    href="https://doi.org/10.1088/1361-6544/aadc12">10.1088/1361-6544/aadc12</a>.
  short: V. Kaloshin, K. Zhang, Nonlinearity 31 (2018) 5214–5234.
date_created: 2020-09-17T10:42:09Z
date_published: 2018-10-15T00:00:00Z
date_updated: 2021-01-12T08:19:10Z
day: '15'
doi: 10.1088/1361-6544/aadc12
extern: '1'
external_id:
  arxiv:
  - '1706.07968'
intvolume: '        31'
issue: '11'
keyword:
- Mathematical Physics
- General Physics and Astronomy
- Applied Mathematics
- Statistical and Nonlinear Physics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1706.07968
month: '10'
oa: 1
oa_version: Preprint
page: 5214-5234
publication: Nonlinearity
publication_identifier:
  issn:
  - 0951-7715
  - 1361-6544
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
status: public
title: Density of convex billiards with rational caustics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 31
year: '2018'
...
---
_id: '14004'
abstract:
- lang: eng
  text: High-harmonic spectroscopy driven by circularly polarized laser pulses and
    their counterrotating second harmonic is a new branch of attosecond science which
    currently lacks quantitative interpretations. We extend this technique to the
    midinfrared regime and record detailed high-harmonic spectra of several rare-gas
    atoms. These results are compared with the solution of the Schrödinger equation
    in three dimensions and calculations based on the strong-field approximation that
    incorporate accurate scattering-wave recombination matrix elements. A quantum-orbit
    analysis of these results provides a transparent interpretation of the measured
    intensity ratios of symmetry-allowed neighboring harmonics in terms of (i) a set
    of propensity rules related to the angular momentum of the atomic orbitals, (ii)
    atom-specific matrix elements related to their electronic structure, and (iii)
    the interference of the emissions associated with electrons in orbitals corotating
    or counterrotating with the laser fields. These results provide the foundation
    for a quantitative understanding of bicircular high-harmonic spectroscopy.
article_number: '203201'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Simon
  full_name: Brennecke, Simon
  last_name: Brennecke
- first_name: Manfred
  full_name: Lein, Manfred
  last_name: Lein
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Baykusheva DR, Brennecke S, Lein M, Wörner HJ. Signatures of electronic structure
    in bicircular high-harmonic spectroscopy. <i>Physical Review Letters</i>. 2017;119(20).
    doi:<a href="https://doi.org/10.1103/physrevlett.119.203201">10.1103/physrevlett.119.203201</a>
  apa: Baykusheva, D. R., Brennecke, S., Lein, M., &#38; Wörner, H. J. (2017). Signatures
    of electronic structure in bicircular high-harmonic spectroscopy. <i>Physical
    Review Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevlett.119.203201">https://doi.org/10.1103/physrevlett.119.203201</a>
  chicago: Baykusheva, Denitsa Rangelova, Simon Brennecke, Manfred Lein, and Hans
    Jakob Wörner. “Signatures of Electronic Structure in Bicircular High-Harmonic
    Spectroscopy.” <i>Physical Review Letters</i>. American Physical Society, 2017.
    <a href="https://doi.org/10.1103/physrevlett.119.203201">https://doi.org/10.1103/physrevlett.119.203201</a>.
  ieee: D. R. Baykusheva, S. Brennecke, M. Lein, and H. J. Wörner, “Signatures of
    electronic structure in bicircular high-harmonic spectroscopy,” <i>Physical Review
    Letters</i>, vol. 119, no. 20. American Physical Society, 2017.
  ista: Baykusheva DR, Brennecke S, Lein M, Wörner HJ. 2017. Signatures of electronic
    structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 119(20),
    203201.
  mla: Baykusheva, Denitsa Rangelova, et al. “Signatures of Electronic Structure in
    Bicircular High-Harmonic Spectroscopy.” <i>Physical Review Letters</i>, vol. 119,
    no. 20, 203201, American Physical Society, 2017, doi:<a href="https://doi.org/10.1103/physrevlett.119.203201">10.1103/physrevlett.119.203201</a>.
  short: D.R. Baykusheva, S. Brennecke, M. Lein, H.J. Wörner, Physical Review Letters
    119 (2017).
date_created: 2023-08-10T06:35:51Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2023-08-22T08:21:10Z
day: '17'
doi: 10.1103/physrevlett.119.203201
extern: '1'
external_id:
  arxiv:
  - '1710.04474'
intvolume: '       119'
issue: '20'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1710.04474
month: '11'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Signatures of electronic structure in bicircular high-harmonic spectroscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '14005'
abstract:
- lang: eng
  text: Strong-field photoelectron holography and laser-induced electron diffraction
    (LIED) are two powerful emerging methods for probing the ultrafast dynamics of
    molecules. However, both of them have remained restricted to static systems and
    to nuclear dynamics induced by strong-field ionization. Here we extend these promising
    methods to image purely electronic valence-shell dynamics in molecules using photoelectron
    holography. In the same experiment, we use LIED and photoelectron holography simultaneously,
    to observe coupled electronic-rotational dynamics taking place on similar timescales.
    These results offer perspectives for imaging ultrafast dynamics of molecules on
    femtosecond to attosecond timescales.
article_number: '15651'
article_processing_charge: No
article_type: original
author:
- first_name: Samuel G.
  full_name: Walt, Samuel G.
  last_name: Walt
- first_name: Niraghatam
  full_name: Bhargava Ram, Niraghatam
  last_name: Bhargava Ram
- first_name: Marcos
  full_name: Atala, Marcos
  last_name: Atala
- first_name: Nikolay I
  full_name: Shvetsov-Shilovski, Nikolay I
  last_name: Shvetsov-Shilovski
- first_name: Aaron
  full_name: von Conta, Aaron
  last_name: von Conta
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Manfred
  full_name: Lein, Manfred
  last_name: Lein
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Walt SG, Bhargava Ram N, Atala M, et al. Dynamics of valence-shell electrons
    and nuclei probed by strong-field holography and rescattering. <i>Nature Communications</i>.
    2017;8. doi:<a href="https://doi.org/10.1038/ncomms15651">10.1038/ncomms15651</a>
  apa: Walt, S. G., Bhargava Ram, N., Atala, M., Shvetsov-Shilovski, N. I., von Conta,
    A., Baykusheva, D. R., … Wörner, H. J. (2017). Dynamics of valence-shell electrons
    and nuclei probed by strong-field holography and rescattering. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/ncomms15651">https://doi.org/10.1038/ncomms15651</a>
  chicago: Walt, Samuel G., Niraghatam Bhargava Ram, Marcos Atala, Nikolay I Shvetsov-Shilovski,
    Aaron von Conta, Denitsa Rangelova Baykusheva, Manfred Lein, and Hans Jakob Wörner.
    “Dynamics of Valence-Shell Electrons and Nuclei Probed by Strong-Field Holography
    and Rescattering.” <i>Nature Communications</i>. Springer Nature, 2017. <a href="https://doi.org/10.1038/ncomms15651">https://doi.org/10.1038/ncomms15651</a>.
  ieee: S. G. Walt <i>et al.</i>, “Dynamics of valence-shell electrons and nuclei
    probed by strong-field holography and rescattering,” <i>Nature Communications</i>,
    vol. 8. Springer Nature, 2017.
  ista: Walt SG, Bhargava Ram N, Atala M, Shvetsov-Shilovski NI, von Conta A, Baykusheva
    DR, Lein M, Wörner HJ. 2017. Dynamics of valence-shell electrons and nuclei probed
    by strong-field holography and rescattering. Nature Communications. 8, 15651.
  mla: Walt, Samuel G., et al. “Dynamics of Valence-Shell Electrons and Nuclei Probed
    by Strong-Field Holography and Rescattering.” <i>Nature Communications</i>, vol.
    8, 15651, Springer Nature, 2017, doi:<a href="https://doi.org/10.1038/ncomms15651">10.1038/ncomms15651</a>.
  short: S.G. Walt, N. Bhargava Ram, M. Atala, N.I. Shvetsov-Shilovski, A. von Conta,
    D.R. Baykusheva, M. Lein, H.J. Wörner, Nature Communications 8 (2017).
date_created: 2023-08-10T06:36:09Z
date_published: 2017-06-15T00:00:00Z
date_updated: 2023-08-22T08:26:06Z
day: '15'
doi: 10.1038/ncomms15651
extern: '1'
external_id:
  pmid:
  - '28643771'
intvolume: '         8'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/ncomms15651
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamics of valence-shell electrons and nuclei probed by strong-field holography
  and rescattering
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '14006'
abstract:
- lang: eng
  text: We present a theoretical formalism for the calculation of attosecond delays
    in molecular photoionization. It is shown how delays relevant to one-photon-ionization,
    also known as Eisenbud-Wigner-Smith delays, can be obtained from the complex dipole
    matrix elements provided by molecular quantum scattering theory. These results
    are used to derive formulae for the delays measured by two-photon attosecond interferometry
    based on an attosecond pulse train and a dressing femtosecond infrared pulse.
    These effective delays are first expressed in the molecular frame where maximal
    information about the molecular photoionization dynamics is available. The effects
    of averaging over the emission direction of the electron and the molecular orientation
    are introduced analytically. We illustrate this general formalism for the case
    of two polyatomic molecules. N2O serves as an example of a polar linear molecule
    characterized by complex photoionization dynamics resulting from the presence
    of molecular shape resonances. H2O illustrates the case of a non-linear molecule
    with comparably simple photoionization dynamics resulting from a flat continuum.
    Our theory establishes the foundation for interpreting measurements of the photoionization
    dynamics of all molecules by attosecond metrology.
article_number: '124306'
article_processing_charge: No
article_type: original
author:
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Baykusheva DR, Wörner HJ. Theory of attosecond delays in molecular photoionization.
    <i>The Journal of Chemical Physics</i>. 2017;146(12). doi:<a href="https://doi.org/10.1063/1.4977933">10.1063/1.4977933</a>
  apa: Baykusheva, D. R., &#38; Wörner, H. J. (2017). Theory of attosecond delays
    in molecular photoionization. <i>The Journal of Chemical Physics</i>. AIP Publishing.
    <a href="https://doi.org/10.1063/1.4977933">https://doi.org/10.1063/1.4977933</a>
  chicago: Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Theory of Attosecond
    Delays in Molecular Photoionization.” <i>The Journal of Chemical Physics</i>.
    AIP Publishing, 2017. <a href="https://doi.org/10.1063/1.4977933">https://doi.org/10.1063/1.4977933</a>.
  ieee: D. R. Baykusheva and H. J. Wörner, “Theory of attosecond delays in molecular
    photoionization,” <i>The Journal of Chemical Physics</i>, vol. 146, no. 12. AIP
    Publishing, 2017.
  ista: Baykusheva DR, Wörner HJ. 2017. Theory of attosecond delays in molecular photoionization.
    The Journal of Chemical Physics. 146(12), 124306.
  mla: Baykusheva, Denitsa Rangelova, and Hans Jakob Wörner. “Theory of Attosecond
    Delays in Molecular Photoionization.” <i>The Journal of Chemical Physics</i>,
    vol. 146, no. 12, 124306, AIP Publishing, 2017, doi:<a href="https://doi.org/10.1063/1.4977933">10.1063/1.4977933</a>.
  short: D.R. Baykusheva, H.J. Wörner, The Journal of Chemical Physics 146 (2017).
date_created: 2023-08-10T06:36:19Z
date_published: 2017-03-28T00:00:00Z
date_updated: 2023-08-22T08:30:59Z
day: '28'
doi: 10.1063/1.4977933
extern: '1'
external_id:
  pmid:
  - '28388142'
intvolume: '       146'
issue: '12'
keyword:
- Physical and Theoretical Chemistry
- General Physics and Astronomy
language:
- iso: eng
month: '03'
oa_version: None
pmid: 1
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Theory of attosecond delays in molecular photoionization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 146
year: '2017'
...
---
_id: '14031'
abstract:
- lang: eng
  text: High-harmonic spectroscopy driven by circularly polarized laser pulses and
    their counterrotating second harmonic is a new branch of attosecond science which
    currently lacks quantitative interpretations. We extend this technique to the
    midinfrared regime and record detailed high-harmonic spectra of several rare-gas
    atoms. These results are compared with the solution of the Schrödinger equation
    in three dimensions and calculations based on the strong-field approximation that
    incorporate accurate scattering-wave recombination matrix elements. A quantum-orbit
    analysis of these results provides a transparent interpretation of the measured
    intensity ratios of symmetry-allowed neighboring harmonics in terms of (i) a set
    of propensity rules related to the angular momentum of the atomic orbitals, (ii)
    atom-specific matrix elements related to their electronic structure, and (iii)
    the interference of the emissions associated with electrons in orbitals corotating
    or counterrotating with the laser fields. These results provide the foundation
    for a quantitative understanding of bicircular high-harmonic spectroscopy.
article_number: '203201'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Simon
  full_name: Brennecke, Simon
  last_name: Brennecke
- first_name: Manfred
  full_name: Lein, Manfred
  last_name: Lein
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Baykusheva DR, Brennecke S, Lein M, Wörner HJ. Signatures of electronic structure
    in bicircular high-harmonic spectroscopy. <i>Physical Review Letters</i>. 2017;119(20).
    doi:<a href="https://doi.org/10.1103/physrevlett.119.203201">10.1103/physrevlett.119.203201</a>
  apa: Baykusheva, D. R., Brennecke, S., Lein, M., &#38; Wörner, H. J. (2017). Signatures
    of electronic structure in bicircular high-harmonic spectroscopy. <i>Physical
    Review Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevlett.119.203201">https://doi.org/10.1103/physrevlett.119.203201</a>
  chicago: Baykusheva, Denitsa Rangelova, Simon Brennecke, Manfred Lein, and Hans
    Jakob Wörner. “Signatures of Electronic Structure in Bicircular High-Harmonic
    Spectroscopy.” <i>Physical Review Letters</i>. American Physical Society, 2017.
    <a href="https://doi.org/10.1103/physrevlett.119.203201">https://doi.org/10.1103/physrevlett.119.203201</a>.
  ieee: D. R. Baykusheva, S. Brennecke, M. Lein, and H. J. Wörner, “Signatures of
    electronic structure in bicircular high-harmonic spectroscopy,” <i>Physical Review
    Letters</i>, vol. 119, no. 20. American Physical Society, 2017.
  ista: Baykusheva DR, Brennecke S, Lein M, Wörner HJ. 2017. Signatures of electronic
    structure in bicircular high-harmonic spectroscopy. Physical Review Letters. 119(20),
    203201.
  mla: Baykusheva, Denitsa Rangelova, et al. “Signatures of Electronic Structure in
    Bicircular High-Harmonic Spectroscopy.” <i>Physical Review Letters</i>, vol. 119,
    no. 20, 203201, American Physical Society, 2017, doi:<a href="https://doi.org/10.1103/physrevlett.119.203201">10.1103/physrevlett.119.203201</a>.
  short: D.R. Baykusheva, S. Brennecke, M. Lein, H.J. Wörner, Physical Review Letters
    119 (2017).
date_created: 2023-08-10T06:48:12Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2023-08-22T06:48:28Z
day: '17'
doi: 10.1103/physrevlett.119.203201
extern: '1'
external_id:
  arxiv:
  - '1710.04474'
  pmid:
  - '29219334'
intvolume: '       119'
issue: '20'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1710.04474
month: '11'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Signatures of electronic structure in bicircular high-harmonic spectroscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '11065'
abstract:
- lang: eng
  text: Premature aging disorders provide an opportunity to study the mechanisms that
    drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of
    the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins.
    We sought to investigate protein homeostasis in this disease. Here, we report
    a widespread increase in protein turnover in HGPS-derived cells compared to normal
    cells. We determine that global protein synthesis is elevated as a consequence
    of activated nucleoli and enhanced ribosome biogenesis in HGPS-derived fibroblasts.
    Depleting normal lamin A or inducing mutant lamin A expression are each sufficient
    to drive nucleolar expansion. We further show that nucleolar size correlates with
    donor age in primary fibroblasts derived from healthy individuals and that ribosomal
    RNA production increases with age, indicating that nucleolar size and activity
    can serve as aging biomarkers. While limiting ribosome biogenesis extends lifespan
    in several systems, we show that increased ribosome biogenesis and activity are
    a hallmark of premature aging.
article_number: '328'
article_processing_charge: No
article_type: original
author:
- first_name: Abigail
  full_name: Buchwalter, Abigail
  last_name: Buchwalter
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Buchwalter A, Hetzer M. Nucleolar expansion and elevated protein translation
    in premature aging. <i>Nature Communications</i>. 2017;8. doi:<a href="https://doi.org/10.1038/s41467-017-00322-z">10.1038/s41467-017-00322-z</a>
  apa: Buchwalter, A., &#38; Hetzer, M. (2017). Nucleolar expansion and elevated protein
    translation in premature aging. <i>Nature Communications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41467-017-00322-z">https://doi.org/10.1038/s41467-017-00322-z</a>
  chicago: Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated
    Protein Translation in Premature Aging.” <i>Nature Communications</i>. Springer
    Nature, 2017. <a href="https://doi.org/10.1038/s41467-017-00322-z">https://doi.org/10.1038/s41467-017-00322-z</a>.
  ieee: A. Buchwalter and M. Hetzer, “Nucleolar expansion and elevated protein translation
    in premature aging,” <i>Nature Communications</i>, vol. 8. Springer Nature, 2017.
  ista: Buchwalter A, Hetzer M. 2017. Nucleolar expansion and elevated protein translation
    in premature aging. Nature Communications. 8, 328.
  mla: Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein
    Translation in Premature Aging.” <i>Nature Communications</i>, vol. 8, 328, Springer
    Nature, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-00322-z">10.1038/s41467-017-00322-z</a>.
  short: A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).
date_created: 2022-04-07T07:45:50Z
date_published: 2017-08-30T00:00:00Z
date_updated: 2024-10-14T11:20:12Z
day: '30'
doi: 10.1038/s41467-017-00322-z
extern: '1'
external_id:
  pmid:
  - '28855503'
intvolume: '         8'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41467-017-00322-z
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nucleolar expansion and elevated protein translation in premature aging
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '14010'
abstract:
- lang: eng
  text: We report measurements of energy-dependent attosecond photoionization delays
    between the two outer-most valence shells of N2O and H2O. The combination of single-shot
    signal referencing with the use of different metal foils to filter the attosecond
    pulse train enables us to extract delays from congested spectra. Remarkably large
    delays up to 160 as are observed in N2O, whereas the delays in H2O are all smaller
    than 50 as in the photon-energy range of 20-40 eV. These results are interpreted
    by developing a theory of molecular photoionization delays. The long delays measured
    in N2O are shown to reflect the population of molecular shape resonances that
    trap the photoelectron for a duration of up to ∼110 as. The unstructured continua
    of H2O result in much smaller delays at the same photon energies. Our experimental
    and theoretical methods make the study of molecular attosecond photoionization
    dynamics accessible.
article_number: '093001'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Martin
  full_name: Huppert, Martin
  last_name: Huppert
- first_name: Inga
  full_name: Jordan, Inga
  last_name: Jordan
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Aaron
  full_name: von Conta, Aaron
  last_name: von Conta
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Huppert M, Jordan I, Baykusheva DR, von Conta A, Wörner HJ. Attosecond delays
    in molecular photoionization. <i>Physical Review Letters</i>. 2016;117(9). doi:<a
    href="https://doi.org/10.1103/physrevlett.117.093001">10.1103/physrevlett.117.093001</a>
  apa: Huppert, M., Jordan, I., Baykusheva, D. R., von Conta, A., &#38; Wörner, H.
    J. (2016). Attosecond delays in molecular photoionization. <i>Physical Review
    Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevlett.117.093001">https://doi.org/10.1103/physrevlett.117.093001</a>
  chicago: Huppert, Martin, Inga Jordan, Denitsa Rangelova Baykusheva, Aaron von Conta,
    and Hans Jakob Wörner. “Attosecond Delays in Molecular Photoionization.” <i>Physical
    Review Letters</i>. American Physical Society, 2016. <a href="https://doi.org/10.1103/physrevlett.117.093001">https://doi.org/10.1103/physrevlett.117.093001</a>.
  ieee: M. Huppert, I. Jordan, D. R. Baykusheva, A. von Conta, and H. J. Wörner, “Attosecond
    delays in molecular photoionization,” <i>Physical Review Letters</i>, vol. 117,
    no. 9. American Physical Society, 2016.
  ista: Huppert M, Jordan I, Baykusheva DR, von Conta A, Wörner HJ. 2016. Attosecond
    delays in molecular photoionization. Physical Review Letters. 117(9), 093001.
  mla: Huppert, Martin, et al. “Attosecond Delays in Molecular Photoionization.” <i>Physical
    Review Letters</i>, vol. 117, no. 9, 093001, American Physical Society, 2016,
    doi:<a href="https://doi.org/10.1103/physrevlett.117.093001">10.1103/physrevlett.117.093001</a>.
  short: M. Huppert, I. Jordan, D.R. Baykusheva, A. von Conta, H.J. Wörner, Physical
    Review Letters 117 (2016).
date_created: 2023-08-10T06:37:07Z
date_published: 2016-08-26T00:00:00Z
date_updated: 2023-08-22T08:42:50Z
day: '26'
doi: 10.1103/physrevlett.117.093001
extern: '1'
external_id:
  arxiv:
  - '1607.07435'
  pmid:
  - '27610849'
intvolume: '       117'
issue: '9'
keyword:
- General Physics and Astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1607.07435
month: '08'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Attosecond delays in molecular photoionization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 117
year: '2016'
...
---
_id: '14011'
abstract:
- lang: eng
  text: We introduce bicircular high-harmonic spectroscopy as a new method to probe
    dynamical symmetries of atoms and molecules and their evolution in time. Our approach
    is based on combining a circularly polarized femtosecond fundamental field of
    frequency ω with its counterrotating second harmonic 2ω. We demonstrate the ability
    of bicircular high-harmonic spectroscopy to characterize the orbital angular momentum
    symmetry of atomic orbitals. We further show that breaking the threefold rotational
    symmetry of the generating medium-at the level of either the ensemble or that
    of a single molecule-results in the emission of the otherwise parity-forbidden
    frequencies 3qω  (q∈N), which provide a background-free probe of dynamical molecular
    symmetries.
article_number: '123001'
article_processing_charge: No
article_type: original
author:
- first_name: Denitsa Rangelova
  full_name: Baykusheva, Denitsa Rangelova
  id: 71b4d059-2a03-11ee-914d-dfa3beed6530
  last_name: Baykusheva
- first_name: Md Sabbir
  full_name: Ahsan, Md Sabbir
  last_name: Ahsan
- first_name: 'Nan'
  full_name: Lin, Nan
  last_name: Lin
- first_name: Hans Jakob
  full_name: Wörner, Hans Jakob
  last_name: Wörner
citation:
  ama: Baykusheva DR, Ahsan MS, Lin N, Wörner HJ. Bicircular high-harmonic spectroscopy
    reveals dynamical symmetries of atoms and molecules. <i>Physical Review Letters</i>.
    2016;116(12). doi:<a href="https://doi.org/10.1103/physrevlett.116.123001">10.1103/physrevlett.116.123001</a>
  apa: Baykusheva, D. R., Ahsan, M. S., Lin, N., &#38; Wörner, H. J. (2016). Bicircular
    high-harmonic spectroscopy reveals dynamical symmetries of atoms and molecules.
    <i>Physical Review Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevlett.116.123001">https://doi.org/10.1103/physrevlett.116.123001</a>
  chicago: Baykusheva, Denitsa Rangelova, Md Sabbir Ahsan, Nan Lin, and Hans Jakob
    Wörner. “Bicircular High-Harmonic Spectroscopy Reveals Dynamical Symmetries of
    Atoms and Molecules.” <i>Physical Review Letters</i>. American Physical Society,
    2016. <a href="https://doi.org/10.1103/physrevlett.116.123001">https://doi.org/10.1103/physrevlett.116.123001</a>.
  ieee: D. R. Baykusheva, M. S. Ahsan, N. Lin, and H. J. Wörner, “Bicircular high-harmonic
    spectroscopy reveals dynamical symmetries of atoms and molecules,” <i>Physical
    Review Letters</i>, vol. 116, no. 12. American Physical Society, 2016.
  ista: Baykusheva DR, Ahsan MS, Lin N, Wörner HJ. 2016. Bicircular high-harmonic
    spectroscopy reveals dynamical symmetries of atoms and molecules. Physical Review
    Letters. 116(12), 123001.
  mla: Baykusheva, Denitsa Rangelova, et al. “Bicircular High-Harmonic Spectroscopy
    Reveals Dynamical Symmetries of Atoms and Molecules.” <i>Physical Review Letters</i>,
    vol. 116, no. 12, 123001, American Physical Society, 2016, doi:<a href="https://doi.org/10.1103/physrevlett.116.123001">10.1103/physrevlett.116.123001</a>.
  short: D.R. Baykusheva, M.S. Ahsan, N. Lin, H.J. Wörner, Physical Review Letters
    116 (2016).
date_created: 2023-08-10T06:37:16Z
date_published: 2016-03-25T00:00:00Z
date_updated: 2023-08-22T08:44:10Z
day: '25'
doi: 10.1103/physrevlett.116.123001
extern: '1'
external_id:
  pmid:
  - '27058077'
intvolume: '       116'
issue: '12'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '03'
oa_version: None
pmid: 1
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bicircular high-harmonic spectroscopy reveals dynamical symmetries of atoms
  and molecules
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2016'
...
---
_id: '11072'
abstract:
- lang: eng
  text: "Spatiotemporal activation of RhoA and actomyosin contraction underpins cellular
    adhesion and division. Loss of cell–cell adhesion and chromosomal instability
    are cardinal events that drive tumour progression. Here, we show that p120-catenin
    (p120) not only controls cell–cell adhesion, but also acts as a critical regulator
    of cytokinesis. We find that p120 regulates actomyosin contractility through concomitant
    binding to RhoA and the centralspindlin component MKLP1, independent of cadherin
    association. In anaphase, p120 is enriched at the cleavage furrow where it binds
    MKLP1 to spatially control RhoA GTPase cycling. Binding of p120 to MKLP1 during
    cytokinesis depends on the N-terminal coiled-coil domain of p120 isoform 1A. Importantly,
    clinical data show that loss of p120 expression is a common event in breast cancer
    that strongly correlates with multinucleation and adverse patient survival. In
    summary, our study identifies p120 loss as a driver event of chromosomal instability
    in cancer.\r\n"
article_number: '13874'
article_processing_charge: No
article_type: original
author:
- first_name: Robert A.H.
  full_name: van de Ven, Robert A.H.
  last_name: van de Ven
- first_name: Jolien S.
  full_name: de Groot, Jolien S.
  last_name: de Groot
- first_name: Danielle
  full_name: Park, Danielle
  last_name: Park
- first_name: Robert
  full_name: van Domselaar, Robert
  last_name: van Domselaar
- first_name: Danielle
  full_name: de Jong, Danielle
  last_name: de Jong
- first_name: Karoly
  full_name: Szuhai, Karoly
  last_name: Szuhai
- first_name: Elsken
  full_name: van der Wall, Elsken
  last_name: van der Wall
- first_name: Oscar M.
  full_name: Rueda, Oscar M.
  last_name: Rueda
- first_name: H. Raza
  full_name: Ali, H. Raza
  last_name: Ali
- first_name: Carlos
  full_name: Caldas, Carlos
  last_name: Caldas
- first_name: Paul J.
  full_name: van Diest, Paul J.
  last_name: van Diest
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Erik
  full_name: Sahai, Erik
  last_name: Sahai
- first_name: Patrick W.B.
  full_name: Derksen, Patrick W.B.
  last_name: Derksen
citation:
  ama: van de Ven RAH, de Groot JS, Park D, et al. p120-catenin prevents multinucleation
    through control of MKLP1-dependent RhoA activity during cytokinesis. <i>Nature
    Communications</i>. 2016;7. doi:<a href="https://doi.org/10.1038/ncomms13874">10.1038/ncomms13874</a>
  apa: van de Ven, R. A. H., de Groot, J. S., Park, D., van Domselaar, R., de Jong,
    D., Szuhai, K., … Derksen, P. W. B. (2016). p120-catenin prevents multinucleation
    through control of MKLP1-dependent RhoA activity during cytokinesis. <i>Nature
    Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/ncomms13874">https://doi.org/10.1038/ncomms13874</a>
  chicago: Ven, Robert A.H. van de, Jolien S. de Groot, Danielle Park, Robert van
    Domselaar, Danielle de Jong, Karoly Szuhai, Elsken van der Wall, et al. “P120-Catenin
    Prevents Multinucleation through Control of MKLP1-Dependent RhoA Activity during
    Cytokinesis.” <i>Nature Communications</i>. Springer Nature, 2016. <a href="https://doi.org/10.1038/ncomms13874">https://doi.org/10.1038/ncomms13874</a>.
  ieee: R. A. H. van de Ven <i>et al.</i>, “p120-catenin prevents multinucleation
    through control of MKLP1-dependent RhoA activity during cytokinesis,” <i>Nature
    Communications</i>, vol. 7. Springer Nature, 2016.
  ista: van de Ven RAH, de Groot JS, Park D, van Domselaar R, de Jong D, Szuhai K,
    van der Wall E, Rueda OM, Ali HR, Caldas C, van Diest PJ, Hetzer M, Sahai E, Derksen
    PWB. 2016. p120-catenin prevents multinucleation through control of MKLP1-dependent
    RhoA activity during cytokinesis. Nature Communications. 7, 13874.
  mla: van de Ven, Robert A. H., et al. “P120-Catenin Prevents Multinucleation through
    Control of MKLP1-Dependent RhoA Activity during Cytokinesis.” <i>Nature Communications</i>,
    vol. 7, 13874, Springer Nature, 2016, doi:<a href="https://doi.org/10.1038/ncomms13874">10.1038/ncomms13874</a>.
  short: R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong,
    K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M.
    Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).
date_created: 2022-04-07T07:48:34Z
date_published: 2016-12-22T00:00:00Z
date_updated: 2022-07-18T08:34:32Z
day: '22'
doi: 10.1038/ncomms13874
extern: '1'
external_id:
  pmid:
  - '28004812'
intvolume: '         7'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/ncomms13874
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1038/ncomms16030
scopus_import: '1'
status: public
title: p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA
  activity during cytokinesis
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 7
year: '2016'
...
---
_id: '10376'
abstract:
- lang: eng
  text: Nucleation processes are at the heart of a large number of phenomena, from
    cloud formation to protein crystallization. A recently emerging area where nucleation
    is highly relevant is the initiation of filamentous protein self-assembly, a process
    that has broad implications in many research areas ranging from medicine to nanotechnology.
    As such, spontaneous nucleation of protein fibrils has received much attention
    in recent years with many theoretical and experimental studies focusing on the
    underlying physical principles. In this paper we make a step forward in this direction
    and explore the early time behaviour of filamentous protein growth in the context
    of nucleation theory. We first provide an overview of the thermodynamics and kinetics
    of spontaneous nucleation of protein filaments in the presence of one relevant
    degree of freedom, namely the cluster size. In this case, we review how key kinetic
    observables, such as the reaction order of spontaneous nucleation, are directly
    related to the physical size of the critical nucleus. We then focus on the increasingly
    prominent case of filament nucleation that includes a conformational conversion
    of the nucleating building-block as an additional slow step in the nucleation
    process. Using computer simulations, we study the concentration dependence of
    the nucleation rate. We find that, under these circumstances, the reaction order
    of spontaneous nucleation with respect to the free monomer does no longer relate
    to the overall physical size of the nucleating aggregate but rather to the portion
    of the aggregate that actively participates in the conformational conversion.
    Our results thus provide a novel interpretation of the common kinetic descriptors
    of protein filament formation, including the reaction order of the nucleation
    step or the scaling exponent of lag times, and put into perspective current theoretical
    descriptions of protein aggregation.
acknowledgement: We acknowledge support from the Human Frontier Science Program and
  Emmanuel College (A.Š.), St John’s and Peterhouse Colleges (T.C.T.M.), the Swiss
  National Science Foundation (T.C.T.M.), the Biotechnology and Biological Sciences
  Research Council (T.P.J.K.), the Frances and Augustus Newman Foundation (T.P.J.K.),
  the European Research Council (T.C.T.M., T.P.J.K., and D.F.), and the Engineering
  and Physical Sciences Research Council (D.F.).
article_number: '211926'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Thomas C. T.
  full_name: Michaels, Thomas C. T.
  last_name: Michaels
- first_name: Alessio
  full_name: Zaccone, Alessio
  last_name: Zaccone
- first_name: Tuomas P. J.
  full_name: Knowles, Tuomas P. J.
  last_name: Knowles
- first_name: Daan
  full_name: Frenkel, Daan
  last_name: Frenkel
citation:
  ama: 'Šarić A, Michaels TCT, Zaccone A, Knowles TPJ, Frenkel D. Kinetics of spontaneous
    filament nucleation via oligomers: Insights from theory and simulation. <i>The
    Journal of Chemical Physics</i>. 2016;145(21). doi:<a href="https://doi.org/10.1063/1.4965040">10.1063/1.4965040</a>'
  apa: 'Šarić, A., Michaels, T. C. T., Zaccone, A., Knowles, T. P. J., &#38; Frenkel,
    D. (2016). Kinetics of spontaneous filament nucleation via oligomers: Insights
    from theory and simulation. <i>The Journal of Chemical Physics</i>. American Institute
    of Physics. <a href="https://doi.org/10.1063/1.4965040">https://doi.org/10.1063/1.4965040</a>'
  chicago: 'Šarić, Anđela, Thomas C. T. Michaels, Alessio Zaccone, Tuomas P. J. Knowles,
    and Daan Frenkel. “Kinetics of Spontaneous Filament Nucleation via Oligomers:
    Insights from Theory and Simulation.” <i>The Journal of Chemical Physics</i>.
    American Institute of Physics, 2016. <a href="https://doi.org/10.1063/1.4965040">https://doi.org/10.1063/1.4965040</a>.'
  ieee: 'A. Šarić, T. C. T. Michaels, A. Zaccone, T. P. J. Knowles, and D. Frenkel,
    “Kinetics of spontaneous filament nucleation via oligomers: Insights from theory
    and simulation,” <i>The Journal of Chemical Physics</i>, vol. 145, no. 21. American
    Institute of Physics, 2016.'
  ista: 'Šarić A, Michaels TCT, Zaccone A, Knowles TPJ, Frenkel D. 2016. Kinetics
    of spontaneous filament nucleation via oligomers: Insights from theory and simulation.
    The Journal of Chemical Physics. 145(21), 211926.'
  mla: 'Šarić, Anđela, et al. “Kinetics of Spontaneous Filament Nucleation via Oligomers:
    Insights from Theory and Simulation.” <i>The Journal of Chemical Physics</i>,
    vol. 145, no. 21, 211926, American Institute of Physics, 2016, doi:<a href="https://doi.org/10.1063/1.4965040">10.1063/1.4965040</a>.'
  short: A. Šarić, T.C.T. Michaels, A. Zaccone, T.P.J. Knowles, D. Frenkel, The Journal
    of Chemical Physics 145 (2016).
date_created: 2021-11-29T10:01:57Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2021-11-29T10:33:11Z
day: '01'
doi: 10.1063/1.4965040
extern: '1'
external_id:
  arxiv:
  - '1610.02320'
  pmid:
  - '28799382'
intvolume: '       145'
issue: '21'
keyword:
- physical and theoretical chemistry
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1610.02320
month: '12'
oa: 1
oa_version: Preprint
pmid: 1
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: American Institute of Physics
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Kinetics of spontaneous filament nucleation via oligomers: Insights from theory
  and simulation'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 145
year: '2016'
...
---
_id: '10378'
abstract:
- lang: eng
  text: The ability of biological molecules to replicate themselves is the foundation
    of life, requiring a complex cellular machinery. However, a range of aberrant
    processes involve the self-replication of pathological protein structures without
    any additional assistance. One example is the autocatalytic generation of pathological
    protein aggregates, including amyloid fibrils, involved in neurodegenerative disorders.
    Here, we use computer simulations to identify the necessary requirements for the
    self-replication of fibrillar assemblies of proteins. We establish that a key
    physical determinant for this process is the affinity of proteins for the surfaces
    of fibrils. We find that self-replication can take place only in a very narrow
    regime of inter-protein interactions, implying a high level of sensitivity to
    system parameters and experimental conditions. We then compare our theoretical
    predictions with kinetic and biosensor measurements of fibrils formed from the
    Aβ peptide associated with Alzheimer’s disease. Our results show a quantitative
    connection between the kinetics of self-replication and the surface coverage of
    fibrils by monomeric proteins. These findings reveal the fundamental physical
    requirements for the formation of supra-molecular structures able to replicate
    themselves, and shed light on mechanisms in play in the proliferation of protein
    aggregates in nature.
acknowledgement: We acknowledge support from the Human Frontier Science Program and
  Emmanuel College (A.Š.), the Leverhulme Trust and Magdalene College (A.K.B.), St
  John’s College (T.C.T.M.), the Biotechnology and Biological Sciences Research Council
  (T.P.J.K. and C.M.D.), the Frances and Augustus Newman Foundation (T.P.J.K.), the
  European Research Council (T.P.J.K., T.C.T.M., S.L. and D.F.), and the Engineering
  and Physical Sciences Research Council (D.F.).
article_processing_charge: No
article_type: original
author:
- first_name: Anđela
  full_name: Šarić, Anđela
  id: bf63d406-f056-11eb-b41d-f263a6566d8b
  last_name: Šarić
  orcid: 0000-0002-7854-2139
- first_name: Alexander K.
  full_name: Buell, Alexander K.
  last_name: Buell
- first_name: Georg
  full_name: Meisl, Georg
  last_name: Meisl
- first_name: Thomas C. T.
  full_name: Michaels, Thomas C. T.
  last_name: Michaels
- first_name: Christopher M.
  full_name: Dobson, Christopher M.
  last_name: Dobson
- first_name: Sara
  full_name: Linse, Sara
  last_name: Linse
- first_name: Tuomas P. J.
  full_name: Knowles, Tuomas P. J.
  last_name: Knowles
- first_name: Daan
  full_name: Frenkel, Daan
  last_name: Frenkel
citation:
  ama: Šarić A, Buell AK, Meisl G, et al. Physical determinants of the self-replication
    of protein fibrils. <i>Nature Physics</i>. 2016;12(9):874-880. doi:<a href="https://doi.org/10.1038/nphys3828">10.1038/nphys3828</a>
  apa: Šarić, A., Buell, A. K., Meisl, G., Michaels, T. C. T., Dobson, C. M., Linse,
    S., … Frenkel, D. (2016). Physical determinants of the self-replication of protein
    fibrils. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/nphys3828">https://doi.org/10.1038/nphys3828</a>
  chicago: Šarić, Anđela, Alexander K. Buell, Georg Meisl, Thomas C. T. Michaels,
    Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles, and Daan Frenkel. “Physical
    Determinants of the Self-Replication of Protein Fibrils.” <i>Nature Physics</i>.
    Springer Nature, 2016. <a href="https://doi.org/10.1038/nphys3828">https://doi.org/10.1038/nphys3828</a>.
  ieee: A. Šarić <i>et al.</i>, “Physical determinants of the self-replication of
    protein fibrils,” <i>Nature Physics</i>, vol. 12, no. 9. Springer Nature, pp.
    874–880, 2016.
  ista: Šarić A, Buell AK, Meisl G, Michaels TCT, Dobson CM, Linse S, Knowles TPJ,
    Frenkel D. 2016. Physical determinants of the self-replication of protein fibrils.
    Nature Physics. 12(9), 874–880.
  mla: Šarić, Anđela, et al. “Physical Determinants of the Self-Replication of Protein
    Fibrils.” <i>Nature Physics</i>, vol. 12, no. 9, Springer Nature, 2016, pp. 874–80,
    doi:<a href="https://doi.org/10.1038/nphys3828">10.1038/nphys3828</a>.
  short: A. Šarić, A.K. Buell, G. Meisl, T.C.T. Michaels, C.M. Dobson, S. Linse, T.P.J.
    Knowles, D. Frenkel, Nature Physics 12 (2016) 874–880.
date_created: 2021-11-29T10:36:11Z
date_published: 2016-07-18T00:00:00Z
date_updated: 2021-11-29T11:07:25Z
day: '18'
doi: 10.1038/nphys3828
extern: '1'
external_id:
  pmid:
  - '31031819'
intvolume: '        12'
issue: '9'
keyword:
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://discovery.ucl.ac.uk/id/eprint/1517406/
month: '07'
oa: 1
oa_version: Preprint
page: 874-880
pmid: 1
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Physical determinants of the self-replication of protein fibrils
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 12
year: '2016'
...
