[{"abstract":[{"lang":"eng","text":"Behavioural data for Pokusaeva, Satapathy et al. Relevant information can be found in the 'README.txt' file."}],"title":"Bilateral interactions of optic-flow sensitive neurons coordinate course control in flies","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","type":"research_data","date_created":"2024-09-03T17:42:46Z","related_material":{"record":[{"id":"18444","status":"public","relation":"used_in_publication"}]},"citation":{"mla":"Satapathy, Roshan K., et al. <i>Bilateral Interactions of Optic-Flow Sensitive Neurons Coordinate Course Control in Flies</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:17488\">10.15479/AT:ISTA:17488</a>.","ieee":"R. K. Satapathy, M. A. Jösch, O. Symonova, and V. Pokusaeva, “Bilateral interactions of optic-flow sensitive neurons coordinate course control in flies.” Institute of Science and Technology Austria, 2024.","ama":"Satapathy RK, Jösch MA, Symonova O, Pokusaeva V. Bilateral interactions of optic-flow sensitive neurons coordinate course control in flies. 2024. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:17488\">10.15479/AT:ISTA:17488</a>","ista":"Satapathy RK, Jösch MA, Symonova O, Pokusaeva V. 2024. Bilateral interactions of optic-flow sensitive neurons coordinate course control in flies, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:17488\">10.15479/AT:ISTA:17488</a>.","short":"R.K. Satapathy, M.A. Jösch, O. Symonova, V. Pokusaeva, (2024).","chicago":"Satapathy, Roshan K, Maximilian A Jösch, Olga Symonova, and Victoria Pokusaeva. “Bilateral Interactions of Optic-Flow Sensitive Neurons Coordinate Course Control in Flies.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/AT:ISTA:17488\">https://doi.org/10.15479/AT:ISTA:17488</a>.","apa":"Satapathy, R. K., Jösch, M. A., Symonova, O., &#38; Pokusaeva, V. (2024). Bilateral interactions of optic-flow sensitive neurons coordinate course control in flies. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:17488\">https://doi.org/10.15479/AT:ISTA:17488</a>"},"keyword":["drosophila","behaviour","locomotion","gap junctions"],"department":[{"_id":"GradSch"},{"_id":"MaJö"}],"article_processing_charge":"No","project":[{"name":"Evolution of Sensorimotor Transformation Across Diptera","_id":"9B767A34-BA93-11EA-9121-9846C619BF3A","grant_number":"429960716"}],"acknowledged_ssus":[{"_id":"M-Shop"}],"_id":"17488","publisher":"Institute of Science and Technology Austria","has_accepted_license":"1","date_published":"2024-09-01T00:00:00Z","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2026-06-10T07:58:35Z","file_date_updated":"2024-09-03T17:39:32Z","corr_author":"1","month":"09","oa":1,"ddc":["570"],"year":"2024","doi":"10.15479/AT:ISTA:17488","status":"public","author":[{"last_name":"Satapathy","full_name":"Satapathy, Roshan K","first_name":"Roshan K","id":"46046B7A-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0006-2974-5075"},{"first_name":"Maximilian A","full_name":"Jösch, Maximilian A","last_name":"Jösch","orcid":"0000-0002-3937-1330","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Symonova, Olga","last_name":"Symonova","first_name":"Olga","id":"3C0C7BC6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2012-9947"},{"full_name":"Pokusaeva, Victoria","last_name":"Pokusaeva","first_name":"Victoria","id":"3184041C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7660-444X"}],"file":[{"access_level":"open_access","checksum":"df9d6c8ddffa046c3b1639281f83cfcf","success":1,"file_size":965778072,"file_id":"17489","file_name":"BehaviouralData.zip","relation":"main_file","date_updated":"2024-09-03T17:39:32Z","date_created":"2024-09-03T17:39:32Z","creator":"rsatapat","content_type":"application/x-zip-compressed"}]},{"abstract":[{"text":"The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here we uncovered a progenitor cell allocation mechanism that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues. Progenitors of the zebrafish laterality organ originate from the surface epithelial enveloping layer by an apical constriction process of cell delamination. During this process, progenitors retain long-term apical contacts that enable the epithelial layer to pull a subset of progenitors along their way towards the vegetal pole. The remaining delaminated progenitors follow apically-attached progenitors’ movement by a co-attraction mechanism, avoiding sequestration by the adjacent endoderm, ensuring their fate and collective allocation at the differentiation site. Thus, we reveal that incomplete delamination serves as a cellular platform for coordinated tissue movements during development. Impact Statement: Incomplete delamination serves as a cellular platform for coordinated tissue movements during development, guiding newly formed progenitor cell groups to the differentiation site.","lang":"eng"}],"title":"Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism","type":"journal_article","keyword":["cell delamination","apical constriction","dragging","mechanical forces","collective 18 locomotion","dorsal forerunner cells","zebrafish"],"isi":1,"department":[{"_id":"CaHe"}],"article_processing_charge":"Yes","_id":"9999","quality_controlled":"1","volume":10,"has_accepted_license":"1","pmid":1,"file_date_updated":"2022-05-13T08:03:37Z","ec_funded":1,"year":"2021","intvolume":"        10","status":"public","file":[{"access_level":"open_access","checksum":"a3f82b0499cc822ac1eab48a01f3f57e","success":1,"file_size":9010446,"file_id":"11371","relation":"main_file","file_name":"2021_eLife_Pulgar.pdf","date_updated":"2022-05-13T08:03:37Z","date_created":"2022-05-13T08:03:37Z","creator":"dernst","content_type":"application/pdf"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication":"eLife","date_created":"2021-09-12T22:01:23Z","citation":{"ama":"Pulgar E, Schwayer C, Guerrero N, et al. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. <i>eLife</i>. 2021;10. doi:<a href=\"https://doi.org/10.7554/eLife.66483\">10.7554/eLife.66483</a>","chicago":"Pulgar, Eduardo, Cornelia Schwayer, Néstor Guerrero, Loreto López, Susana Márquez, Steffen Härtel, Rodrigo Soto, Carl Philipp Heisenberg, and Miguel L. Concha. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor Cell Allocation through a Dragging Mechanism.” <i>ELife</i>. eLife Sciences Publications, 2021. <a href=\"https://doi.org/10.7554/eLife.66483\">https://doi.org/10.7554/eLife.66483</a>.","short":"E. Pulgar, C. Schwayer, N. Guerrero, L. López, S. Márquez, S. Härtel, R. Soto, C.P. Heisenberg, M.L. Concha, ELife 10 (2021).","ista":"Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML. 2021. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. eLife. 10, e66483.","ieee":"E. Pulgar <i>et al.</i>, “Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism,” <i>eLife</i>, vol. 10. eLife Sciences Publications, 2021.","apa":"Pulgar, E., Schwayer, C., Guerrero, N., López, L., Márquez, S., Härtel, S., … Concha, M. L. (2021). Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.66483\">https://doi.org/10.7554/eLife.66483</a>","mla":"Pulgar, Eduardo, et al. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor Cell Allocation through a Dragging Mechanism.” <i>ELife</i>, vol. 10, e66483, eLife Sciences Publications, 2021, doi:<a href=\"https://doi.org/10.7554/eLife.66483\">10.7554/eLife.66483</a>."},"scopus_import":"1","language":[{"iso":"eng"}],"day":"27","project":[{"call_identifier":"H2020","grant_number":"742573","_id":"260F1432-B435-11E9-9278-68D0E5697425","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation"}],"publication_identifier":{"eissn":["2050-084X"]},"publication_status":"published","publisher":"eLife Sciences Publications","date_published":"2021-08-27T00:00:00Z","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2025-04-14T07:46:58Z","article_number":"e66483","external_id":{"isi":["000700428500001"],"pmid":["34448451"]},"month":"08","ddc":["570"],"oa":1,"article_type":"original","doi":"10.7554/eLife.66483","author":[{"full_name":"Pulgar, Eduardo","last_name":"Pulgar","first_name":"Eduardo"},{"orcid":"0000-0001-5130-2226","id":"3436488C-F248-11E8-B48F-1D18A9856A87","first_name":"Cornelia","full_name":"Schwayer, Cornelia","last_name":"Schwayer"},{"first_name":"Néstor","full_name":"Guerrero, Néstor","last_name":"Guerrero"},{"first_name":"Loreto","last_name":"López","full_name":"López, Loreto"},{"first_name":"Susana","full_name":"Márquez, Susana","last_name":"Márquez"},{"full_name":"Härtel, Steffen","last_name":"Härtel","first_name":"Steffen"},{"full_name":"Soto, Rodrigo","last_name":"Soto","first_name":"Rodrigo"},{"first_name":"Carl Philipp","last_name":"Heisenberg","full_name":"Heisenberg, Carl Philipp"},{"last_name":"Concha","full_name":"Concha, Miguel L.","first_name":"Miguel L."}]}]