---
OA_place: publisher
OA_type: hybrid
_id: '17219'
abstract:
- lang: eng
  text: 'We introduce a multi-material non-manifold mesh-based surface tracking algorithm
    that converts self-intersections into topological changes. Our algorithm generalizes
    prior work on manifold surface tracking with topological changes: it preserves
    surface features like mesh-based methods, and it robustly handles topological
    changes like level set methods. Our method also offers improved efficiency and
    robustness over the state of the art. We demonstrate the effectiveness of the
    approach on a range of examples, including complex soap film simulations with
    thousands of interacting bubbles, and boolean unions of non-manifold meshes consisting
    of millions of triangles.'
acknowledgement: Peter Heiss-Synak helped conceive the project, helped formulate the
  algorithm structure, contributed ideas and code to Sections 6 & 8, the mesh data
  structure, algorithm robustness and benchmarks, helped write the paper, and provided
  supervision and conceptual solutions throughout the project. Aleksei Kalinov contributed
  ideas and code to Sections 7, 8.5, and 5, the sparse grid data structure, algorithm
  robustness and benchmarks, optimized the performance, produced all results, most
  figures, and the supplementary video, helped write the text, and provided conceptual
  solutions throughout the project. Malina Strugaru helped implement the mesh data
  structure and designed re-meshing operations for non-manifold triangle meshes. Arian
  Etemadi developed early prototypes for ideas in Sections 8.1 and 8.3 and helped
  write the paper. Huidong Yang developed early prototypes for isosurface extraction
  and visualization. Chris Wojtan helped conceive the project, helped write the paper,
  and provided supervision, prototype grid data structure code, and conceptual solutions
  throughout the project. We thank the anonymous reviewers for their helpful comments,
  the members of the Visual Computing Group at ISTA for their feedback, Christopher
  Batty for discussions about LosTopos, and SideFX for the Houdini Education software
  licenses.  This research was funded in part by the European Union (ERC-2021-COG
  101045083 CoDiNA).
article_number: '54'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Peter
  full_name: Synak, Peter
  id: 331776E2-F248-11E8-B48F-1D18A9856A87
  last_name: Synak
- first_name: Aleksei
  full_name: Kalinov, Aleksei
  id: 44b7120e-eb97-11eb-a6c2-e1557aa81d02
  last_name: Kalinov
  orcid: 0000-0003-2189-3904
- first_name: Irina-Malina
  full_name: Strugaru, Irina-Malina
  id: 2afc607f-f128-11eb-9611-8f2a0dfcf074
  last_name: Strugaru
- first_name: Arian
  full_name: Etemadihaghighi, Arian
  id: 36cea3aa-f38e-11ec-8ae0-c65ae6f6098f
  last_name: Etemadihaghighi
- first_name: Huidong
  full_name: Yang, Huidong
  last_name: Yang
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Synak P, Kalinov A, Strugaru I-M, Etemadi A, Yang H, Wojtan C. Multi-material
    mesh-based surface tracking with implicit topology changes. <i>ACM Transactions
    on Graphics</i>. 2024;43(4). doi:<a href="https://doi.org/10.1145/3658223">10.1145/3658223</a>
  apa: Synak, P., Kalinov, A., Strugaru, I.-M., Etemadi, A., Yang, H., &#38; Wojtan,
    C. (2024). Multi-material mesh-based surface tracking with implicit topology changes.
    <i>ACM Transactions on Graphics</i>. Association for Computing Machinery. <a href="https://doi.org/10.1145/3658223">https://doi.org/10.1145/3658223</a>
  chicago: Synak, Peter, Aleksei Kalinov, Irina-Malina Strugaru, Arian Etemadi, Huidong
    Yang, and Chris Wojtan. “Multi-Material Mesh-Based Surface Tracking with Implicit
    Topology Changes.” <i>ACM Transactions on Graphics</i>. Association for Computing
    Machinery, 2024. <a href="https://doi.org/10.1145/3658223">https://doi.org/10.1145/3658223</a>.
  ieee: P. Synak, A. Kalinov, I.-M. Strugaru, A. Etemadi, H. Yang, and C. Wojtan,
    “Multi-material mesh-based surface tracking with implicit topology changes,” <i>ACM
    Transactions on Graphics</i>, vol. 43, no. 4. Association for Computing Machinery,
    2024.
  ista: Synak P, Kalinov A, Strugaru I-M, Etemadi A, Yang H, Wojtan C. 2024. Multi-material
    mesh-based surface tracking with implicit topology changes. ACM Transactions on
    Graphics. 43(4), 54.
  mla: Synak, Peter, et al. “Multi-Material Mesh-Based Surface Tracking with Implicit
    Topology Changes.” <i>ACM Transactions on Graphics</i>, vol. 43, no. 4, 54, Association
    for Computing Machinery, 2024, doi:<a href="https://doi.org/10.1145/3658223">10.1145/3658223</a>.
  short: P. Synak, A. Kalinov, I.-M. Strugaru, A. Etemadi, H. Yang, C. Wojtan, ACM
    Transactions on Graphics 43 (2024).
corr_author: '1'
date_created: 2024-07-10T12:24:00Z
date_published: 2024-07-01T00:00:00Z
date_updated: 2026-04-07T13:02:36Z
day: '01'
ddc:
- '004'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1145/3658223
external_id:
  isi:
  - '001289270900021'
file:
- access_level: open_access
  checksum: 1917067d4b52d7729019b03560004e43
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-23T06:35:15Z
  date_updated: 2024-07-23T06:35:15Z
  file_id: '17317'
  file_name: 2024_ACMToG_HeissSynak.pdf
  file_size: 48763368
  relation: main_file
  success: 1
- access_level: open_access
  checksum: a4f0e293184bfa034c0c585848806b17
  content_type: video/mp4
  creator: akalinov
  date_created: 2024-07-10T12:23:44Z
  date_updated: 2024-07-10T12:23:44Z
  file_id: '17221'
  file_name: sdtopofixer_final.mp4
  file_size: 48021463
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 18fc310a78ec91651148c45a8b89fa44
  content_type: application/pdf
  creator: akalinov
  date_created: 2025-11-11T09:50:52Z
  date_updated: 2025-11-11T09:50:52Z
  file_id: '20633'
  file_name: SuperDuperTopoFixer.pdf
  file_size: 48639581
  relation: preprint
  title: Authors' version of the text
file_date_updated: 2025-11-11T09:50:52Z
has_accepted_license: '1'
intvolume: '        43'
isi: 1
issue: '4'
keyword:
- surface tracking
- topology change
- non- manifold meshes
- multi-material flows
- solid modeling
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: ACM Transactions on Graphics
publication_identifier:
  eissn:
  - 1557-7368
  issn:
  - 0730-0301
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
  record:
  - id: '19630'
    relation: dissertation_contains
    status: public
  - id: '18301'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Multi-material mesh-based surface tracking with implicit topology changes
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2024'
...
---
OA_place: publisher
_id: '18301'
abstract:
- lang: eng
  text: Physics simulation in computer graphics can bring triangle meshes into topologically
    invalid states. The method in this thesis contributed to Heiss-Synak* and Kalinov*
    et al. [2024] who devised a non-manifold hybrid surface tracker—a surface tracker
    that repairs explicit non-manifold triangle meshes with the help of the implicit
    domain. Specifically, this thesis provides an algorithm for filling the holes
    that are left after removing problematic parts of the mesh.
alternative_title:
- ISTA Master's Thesis
article_processing_charge: No
author:
- first_name: Arian
  full_name: Etemadihaghighi, Arian
  id: 36cea3aa-f38e-11ec-8ae0-c65ae6f6098f
  last_name: Etemadihaghighi
citation:
  ama: Etemadi A. Filling the holes of non-manifold self-intersecting meshes for implicit
    topology changes in surface tracking. 2024. doi:<a href="https://doi.org/10.15479/at:ista:18301">10.15479/at:ista:18301</a>
  apa: Etemadi, A. (2024). <i>Filling the holes of non-manifold self-intersecting
    meshes for implicit topology changes in surface tracking</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/at:ista:18301">https://doi.org/10.15479/at:ista:18301</a>
  chicago: Etemadi, Arian. “Filling the Holes of Non-Manifold Self-Intersecting Meshes
    for Implicit Topology Changes in Surface Tracking.” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/at:ista:18301">https://doi.org/10.15479/at:ista:18301</a>.
  ieee: A. Etemadi, “Filling the holes of non-manifold self-intersecting meshes for
    implicit topology changes in surface tracking,” Institute of Science and Technology
    Austria, 2024.
  ista: Etemadi A. 2024. Filling the holes of non-manifold self-intersecting meshes
    for implicit topology changes in surface tracking. Institute of Science and Technology
    Austria.
  mla: Etemadi, Arian. <i>Filling the Holes of Non-Manifold Self-Intersecting Meshes
    for Implicit Topology Changes in Surface Tracking</i>. Institute of Science and
    Technology Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:18301">10.15479/at:ista:18301</a>.
  short: A. Etemadi, Filling the Holes of Non-Manifold Self-Intersecting Meshes for
    Implicit Topology Changes in Surface Tracking, Institute of Science and Technology
    Austria, 2024.
corr_author: '1'
date_created: 2024-10-11T19:52:20Z
date_published: 2024-10-15T00:00:00Z
date_updated: 2026-04-07T13:02:36Z
day: '15'
ddc:
- '000'
degree_awarded: MS
department:
- _id: GradSch
- _id: ChWo
doi: 10.15479/at:ista:18301
file:
- access_level: open_access
  checksum: 80fb7923e229ad9d39253d7c8a8083d0
  content_type: application/pdf
  creator: aetemadi
  date_created: 2024-10-24T14:34:42Z
  date_updated: 2024-10-24T14:34:42Z
  file_id: '18469'
  file_name: thesis-arian-etemadi.pdf
  file_size: 8914218
  relation: main_file
  success: 1
- access_level: closed
  checksum: 1c02586ed7d441d5ec441867650568d1
  content_type: application/x-zip-compressed
  creator: aetemadi
  date_created: 2024-10-24T14:34:54Z
  date_updated: 2024-10-24T14:34:54Z
  file_id: '18470'
  file_name: thesis-arian-etemadi-latex-source.zip
  file_size: 9802650
  relation: source_file
file_date_updated: 2024-10-24T14:34:54Z
has_accepted_license: '1'
keyword:
- surface tracking
- non-manifold
- hole-filling
- topology change
- multi-material
- solid-modeling
language:
- iso: eng
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: '39'
publication_identifier:
  issn:
  - 2791-4585
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '17219'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
title: Filling the holes of non-manifold self-intersecting meshes for implicit topology
  changes in surface tracking
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
  name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
OA_place: publisher
_id: '17368'
abstract:
- lang: eng
  text: "Recent advancements in molecular diagnostic techniques have enabled the collection
    of\r\nmultiple types of omics data from patients, including genomics, epigenomics,
    proteomics,\r\nand transcriptomics. However, we lack effective methods for integrating
    all these different\r\ndata types and combining them with clinical outcomes to
    study the molecular mechanisms\r\nthat govern pathological phenotypes. We present
    multi-omics BayesW, a penalized Bayesian\r\nregression method that can handle
    general omics data for survival analysis of time-to-event\r\nphenotypes. Our method
    can: (1) accommodate incomplete data by allowing censored\r\nindividuals, (2)
    use continuous time-to-event data to test associations of markers with a\r\nphenotype
    and (3) estimate effects jointly while allowing for independent groups of biological\r\nmarkers.
    Extensive simulations using planted signals on real data demonstrate that our
    model\r\naccurately retrieves the true parameters of the model while controlling
    for false discoveries\r\nand maintaining the expected prediction accuracy. We
    address data correlations by estimating\r\nthe effects jointly, even between omic
    groups, while also estimating the individual variance\r\nexplained by each group.
    We apply our model to two datasets. Using 18,000 individuals from\r\nthe Generation
    Scotland study we model the association of time at onset of Type 2 Diabetes,\r\nStroke,
    Ischemic Disease, and Osteoarthritis from baseline study entry, with 831,724 CpG\r\nmethylation
    probes. We find that large proportions of variation in disease onset times can\r\nbe
    attributed to methylation as measured in whole blood at baseline in individuals
    without\r\ndisease symptoms. We then apply our model to The Cancer Genome Atlas
    (TCGA) pan-cancer\r\ndataset, in which we use 5 types of omics: copy number variation,
    epigenetics, somatic\r\nmutations, miRNA, and gene expression. For cancer survival
    age-at-onset we find that, when\r\nfitting the 5 groups together, almost all variation
    attributable to \"omics\" data is explained by\r\nDNA methylation. When considering
    progression times, both methylation and gene expression\r\nexplain a large part
    of the variance. We found 2 genes that are significantly associated (95%\r\nposterior
    inclusion probability) with cancer survival time, conditional on all other genome-wide\r\nomics
    data variation. Owing to the vast variability of mechanisms characterizing different\r\ncancers,
    there are likely few specific genes with a strong signal in a pan-cancer setting.
    Taken\r\ntogether, we showed the applicability of our multi-omics BayesW model
    to a wide-range of\r\nbiological questions in multi-omics data.\r\n"
alternative_title:
- ISTA Master's Thesis
article_processing_charge: No
author:
- first_name: Ariadna
  full_name: Villanueva Marijuan, Ariadna
  id: e0ae4864-133f-11ed-8f02-adaa8dd27540
  last_name: Villanueva Marijuan
citation:
  ama: Villanueva Marijuan A. Bayesian linear regression for analyzing general omics
    data with time-to-event phenotypes. 2024. doi:<a href="https://doi.org/10.15479/at:ista:17368">10.15479/at:ista:17368</a>
  apa: Villanueva Marijuan, A. (2024). <i>Bayesian linear regression for analyzing
    general omics data with time-to-event phenotypes</i>. Institute of Science and
    Technology Austria. <a href="https://doi.org/10.15479/at:ista:17368">https://doi.org/10.15479/at:ista:17368</a>
  chicago: Villanueva Marijuan, Ariadna. “Bayesian Linear Regression for Analyzing
    General Omics Data with Time-to-Event Phenotypes.” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/at:ista:17368">https://doi.org/10.15479/at:ista:17368</a>.
  ieee: A. Villanueva Marijuan, “Bayesian linear regression for analyzing general
    omics data with time-to-event phenotypes,” Institute of Science and Technology
    Austria, 2024.
  ista: Villanueva Marijuan A. 2024. Bayesian linear regression for analyzing general
    omics data with time-to-event phenotypes. Institute of Science and Technology
    Austria.
  mla: Villanueva Marijuan, Ariadna. <i>Bayesian Linear Regression for Analyzing General
    Omics Data with Time-to-Event Phenotypes</i>. Institute of Science and Technology
    Austria, 2024, doi:<a href="https://doi.org/10.15479/at:ista:17368">10.15479/at:ista:17368</a>.
  short: A. Villanueva Marijuan, Bayesian Linear Regression for Analyzing General
    Omics Data with Time-to-Event Phenotypes, Institute of Science and Technology
    Austria, 2024.
corr_author: '1'
date_created: 2024-08-02T10:52:40Z
date_published: 2024-08-13T00:00:00Z
date_updated: 2026-04-07T13:03:41Z
day: '13'
ddc:
- '610'
degree_awarded: MS
department:
- _id: GradSch
- _id: MaRo
doi: 10.15479/at:ista:17368
file:
- access_level: open_access
  checksum: 0c2daa174609f0c00919dccc5701d375
  content_type: application/pdf
  creator: avillanu
  date_created: 2024-08-14T11:51:24Z
  date_updated: 2025-02-14T23:30:03Z
  embargo: 2025-02-14
  file_id: '17433'
  file_name: Masters_thesis_AriadnaVillanueva.pdf
  file_size: 13052436
  relation: main_file
- access_level: closed
  checksum: e9ed4465dfa539ac4c3a8d4d0b6271a1
  content_type: application/zip
  creator: avillanu
  date_created: 2024-08-14T11:51:57Z
  date_updated: 2025-02-14T23:30:03Z
  embargo_to: open_access
  file_id: '17434'
  file_name: Masters thesis-AriadnaVillanueva.zip
  file_size: 45642547
  relation: source_file
file_date_updated: 2025-02-14T23:30:03Z
has_accepted_license: '1'
keyword:
- Epigenetics
- Multi-omics
- Bayesian regression
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '60'
publication_identifier:
  issn:
  - 2791-4585
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
title: Bayesian linear regression for analyzing general omics data with time-to-event
  phenotypes
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
_id: '12976'
abstract:
- lang: eng
  text: "3D printing based on continuous deposition of materials, such as filament-based
    3D printing, has seen widespread adoption thanks to its versatility in working
    with a wide range of materials. An important shortcoming of this type of technology
    is its limited multi-material capabilities. While there are simple hardware designs
    that enable multi-material printing in principle, the required software is heavily
    underdeveloped. A typical hardware design fuses together individual materials
    fed into a single chamber from multiple inlets before they are deposited. This
    design, however, introduces a time delay between the intended material mixture
    and its actual deposition. In this work, inspired by diverse path planning research
    in robotics, we show that this mechanical challenge can be addressed via improved
    printer control. We propose to formulate the search for optimal multi-material
    printing policies in a reinforcement\r\nlearning setup. We put forward a simple
    numerical deposition model that takes into account the non-linear material mixing
    and delayed material deposition. To validate our system we focus on color fabrication,
    a problem known for its strict requirements for varying material mixtures at a
    high spatial frequency. We demonstrate that our learned control policy outperforms
    state-of-the-art hand-crafted algorithms."
acknowledgement: This work is graciously supported by FWF Lise Meitner (Grant M 3319).
  Kang Liao sincerely thank Emiliano Luci, Chunyu Lin, and Yao Zhao for their huge
  support.
article_processing_charge: No
author:
- first_name: Kang
  full_name: Liao, Kang
  last_name: Liao
- first_name: Thibault
  full_name: Tricard, Thibault
  last_name: Tricard
- first_name: Michael
  full_name: Piovarci, Michael
  id: 62E473F4-5C99-11EA-A40E-AF823DDC885E
  last_name: Piovarci
  orcid: 0000-0002-5062-4474
- first_name: Hans-Peter
  full_name: Seidel, Hans-Peter
  last_name: Seidel
- first_name: Vahid
  full_name: Babaei, Vahid
  last_name: Babaei
citation:
  ama: 'Liao K, Tricard T, Piovarci M, Seidel H-P, Babaei V. Learning deposition policies
    for fused multi-material 3D printing. In: <i>2023 IEEE International Conference
    on Robotics and Automation</i>. Vol 2023. IEEE; 2023:12345-12352. doi:<a href="https://doi.org/10.1109/ICRA48891.2023.10160465">10.1109/ICRA48891.2023.10160465</a>'
  apa: 'Liao, K., Tricard, T., Piovarci, M., Seidel, H.-P., &#38; Babaei, V. (2023).
    Learning deposition policies for fused multi-material 3D printing. In <i>2023
    IEEE International Conference on Robotics and Automation</i> (Vol. 2023, pp. 12345–12352).
    London, United Kingdom: IEEE. <a href="https://doi.org/10.1109/ICRA48891.2023.10160465">https://doi.org/10.1109/ICRA48891.2023.10160465</a>'
  chicago: Liao, Kang, Thibault Tricard, Michael Piovarci, Hans-Peter Seidel, and
    Vahid Babaei. “Learning Deposition Policies for Fused Multi-Material 3D Printing.”
    In <i>2023 IEEE International Conference on Robotics and Automation</i>, 2023:12345–52.
    IEEE, 2023. <a href="https://doi.org/10.1109/ICRA48891.2023.10160465">https://doi.org/10.1109/ICRA48891.2023.10160465</a>.
  ieee: K. Liao, T. Tricard, M. Piovarci, H.-P. Seidel, and V. Babaei, “Learning deposition
    policies for fused multi-material 3D printing,” in <i>2023 IEEE International
    Conference on Robotics and Automation</i>, London, United Kingdom, 2023, vol.
    2023, pp. 12345–12352.
  ista: 'Liao K, Tricard T, Piovarci M, Seidel H-P, Babaei V. 2023. Learning deposition
    policies for fused multi-material 3D printing. 2023 IEEE International Conference
    on Robotics and Automation. ICRA: International Conference on Robotics and Automation
    vol. 2023, 12345–12352.'
  mla: Liao, Kang, et al. “Learning Deposition Policies for Fused Multi-Material 3D
    Printing.” <i>2023 IEEE International Conference on Robotics and Automation</i>,
    vol. 2023, IEEE, 2023, pp. 12345–52, doi:<a href="https://doi.org/10.1109/ICRA48891.2023.10160465">10.1109/ICRA48891.2023.10160465</a>.
  short: K. Liao, T. Tricard, M. Piovarci, H.-P. Seidel, V. Babaei, in:, 2023 IEEE
    International Conference on Robotics and Automation, IEEE, 2023, pp. 12345–12352.
conference:
  end_date: 2023-06-02
  location: London, United Kingdom
  name: 'ICRA: International Conference on Robotics and Automation'
  start_date: 2023-05-29
date_created: 2023-05-16T09:14:09Z
date_published: 2023-07-04T00:00:00Z
date_updated: 2025-04-15T07:43:52Z
day: '04'
ddc:
- '004'
department:
- _id: BeBi
doi: 10.1109/ICRA48891.2023.10160465
external_id:
  isi:
  - '001048371104068'
file:
- access_level: open_access
  checksum: daeaa67124777d88487f933ea3f77164
  content_type: application/pdf
  creator: mpiovarc
  date_created: 2023-05-16T09:12:05Z
  date_updated: 2023-05-16T09:12:05Z
  file_id: '12977'
  file_name: Liao2023.pdf
  file_size: 5367986
  relation: main_file
  success: 1
file_date_updated: 2023-05-16T09:12:05Z
has_accepted_license: '1'
intvolume: '      2023'
isi: 1
keyword:
- reinforcement learning
- deposition
- control
- color
- multi-filament
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 12345-12352
project:
- _id: eb901961-77a9-11ec-83b8-f5c883a62027
  grant_number: M03319
  name: Perception-Aware Appearance Fabrication
publication: 2023 IEEE International Conference on Robotics and Automation
publication_identifier:
  eisbn:
  - '9798350323658'
  issn:
  - 1050-4729
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning deposition policies for fused multi-material 3D printing
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2023
year: '2023'
...
---
OA_place: publisher
_id: '6435'
abstract:
- lang: eng
  text: "Social insect colonies tend to have numerous members which function together
    like a single organism in such harmony that the term ``super-organism'' is often
    used. In this analogy the reproductive caste is analogous to the primordial germ\r\ncells
    of a metazoan, while the sterile worker caste corresponds to somatic cells. The
    worker castes, like tissues, are\r\nin charge of all functions of a living being,
    besides reproduction. The establishment of new super-organismal units\r\n(i.e.
    new colonies) is accomplished by the co-dependent castes. The term oftentimes
    goes beyond a metaphor. We invoke it when we speak about the metabolic rate, thermoregulation,
    nutrient regulation and gas exchange of a social insect colony. Furthermore, we
    assert that the super-organism has an immune system, and benefits from ``social
    immunity''.\r\n\r\nSocial immunity was first summoned by evolutionary biologists
    to resolve the apparent discrepancy between the expected high frequency of disease
    outbreak amongst numerous, closely related tightly-interacting hosts, living in
    stable and microbially-rich environments, against the exceptionally scarce epidemic
    accounts in natural populations. Social\r\nimmunity comprises a multi-layer assembly
    of behaviours which have evolved to effectively keep the pathogenic enemies of
    a colony at bay. The field of social immunity has drawn interest, as it becomes
    increasingly urgent to stop\r\nthe collapse of pollinator species and curb the
    growth of invasive pests. In the past decade, several mechanisms of\r\nsocial
    immune responses have been dissected, but many more questions remain open.\r\n\r\nI
    present my work in two experimental chapters. In the first, I use invasive garden
    ants (*Lasius neglectus*) to study how pathogen load and its distribution among
    nestmates affect the grooming response of the group. Any given group of ants will
    carry out the same total grooming work, but will direct their grooming effort
    towards individuals\r\ncarrying a relatively higher spore load. Contrary to expectation,
    the highest risk of transmission does not stem from grooming highly contaminated
    ants, but instead, we suggest that the grooming response likely minimizes spore
    loss to the environment, reducing contamination from inadvertent pickup from the
    substrate.\r\n\r\nThe second is a comparative developmental approach. I follow
    black garden ant queens (*Lasius niger*) and their colonies from mating flight,
    through hibernation for a year. Colonies which grow fast from the start, have
    a lower chance of survival through hibernation, and those which survive grow at
    a lower pace later. This is true for colonies of naive\r\nand challenged queens.
    Early pathogen exposure of the queens changes colony dynamics in an unexpected
    way: colonies from exposed queens are more likely to grow slowly and recover in
    numbers only after they survive hibernation.\r\n\r\nIn addition to the two experimental
    chapters, this thesis includes a co-authored published review on organisational\r\nimmunity,
    where we enlist the experimental evidence and theoretical framework on which this
    hypothesis is built,\r\nidentify the caveats and underline how the field is ripe
    to overcome them. In a final chapter, I describe my part in\r\ntwo collaborative
    efforts, one to develop an image-based tracker, and the second to develop a classifier
    for ant\r\nbehaviour."
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: M-Shop
- _id: LifeSc
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Barbara E
  full_name: Casillas Perez, Barbara E
  id: 351ED2AA-F248-11E8-B48F-1D18A9856A87
  last_name: Casillas Perez
citation:
  ama: Casillas Perez BE. Collective defenses of garden ants against a fungal pathogen.
    2019. doi:<a href="https://doi.org/10.15479/AT:ISTA:6435">10.15479/AT:ISTA:6435</a>
  apa: Casillas Perez, B. E. (2019). <i>Collective defenses of garden ants against
    a fungal pathogen</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:6435">https://doi.org/10.15479/AT:ISTA:6435</a>
  chicago: Casillas Perez, Barbara E. “Collective Defenses of Garden Ants against
    a Fungal Pathogen.” Institute of Science and Technology Austria, 2019. <a href="https://doi.org/10.15479/AT:ISTA:6435">https://doi.org/10.15479/AT:ISTA:6435</a>.
  ieee: B. E. Casillas Perez, “Collective defenses of garden ants against a fungal
    pathogen,” Institute of Science and Technology Austria, 2019.
  ista: Casillas Perez BE. 2019. Collective defenses of garden ants against a fungal
    pathogen. Institute of Science and Technology Austria.
  mla: Casillas Perez, Barbara E. <i>Collective Defenses of Garden Ants against a
    Fungal Pathogen</i>. Institute of Science and Technology Austria, 2019, doi:<a
    href="https://doi.org/10.15479/AT:ISTA:6435">10.15479/AT:ISTA:6435</a>.
  short: B.E. Casillas Perez, Collective Defenses of Garden Ants against a Fungal
    Pathogen, Institute of Science and Technology Austria, 2019.
corr_author: '1'
date_created: 2019-05-13T08:58:35Z
date_published: 2019-05-07T00:00:00Z
date_updated: 2026-04-08T14:02:12Z
day: '07'
ddc:
- '570'
- '006'
- '578'
- '592'
degree_awarded: PhD
department:
- _id: SyCr
doi: 10.15479/AT:ISTA:6435
ec_funded: 1
file:
- access_level: open_access
  checksum: 6daf2d2086111aa8fd3fbc919a3e2833
  content_type: application/pdf
  creator: casillas
  date_created: 2019-05-13T09:16:20Z
  date_updated: 2021-02-11T11:17:15Z
  embargo: 2020-05-08
  file_id: '6438'
  file_name: tesisDoctoradoBC.pdf
  file_size: 3895187
  relation: main_file
- access_level: closed
  checksum: 3d221aaff7559a7060230a1ff610594f
  content_type: application/zip
  creator: casillas
  date_created: 2019-05-13T09:16:20Z
  date_updated: 2020-07-14T12:47:30Z
  embargo_to: open_access
  file_id: '6439'
  file_name: tesisDoctoradoBC.zip
  file_size: 7365118
  relation: source_file
file_date_updated: 2021-02-11T11:17:15Z
has_accepted_license: '1'
keyword:
- Social Immunity
- Sanitary care
- Social Insects
- Organisational Immunity
- Colony development
- Multi-target tracking
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '183'
project:
- _id: 2649B4DE-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771402'
  name: Epidemics in ant societies on a chip
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1999'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Sylvia M
  full_name: Cremer, Sylvia M
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
title: Collective defenses of garden ants against a fungal pathogen
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2019'
...
---
_id: '5560'
abstract:
- lang: eng
  text: "This repository contains the data collected for the manuscript \"Biased partitioning
    of the multi-drug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity\".\r\nThe
    data is compressed into a single archive. Within the archive, different folders
    correspond to figures of the main text and the SI of the related publication.\r\nData
    is saved as plain text, with each folder containing a separate readme file describing
    the format. Typically, the data is from fluorescence microscopy measurements of
    single cells growing in a microfluidic \"mother machine\" device, and consists
    of relevant values (primarily arbitrary unit or normalized fluorescence measurements,
    and division times / growth rates) after raw microscopy images have been processed,
    segmented, and their features extracted, as described in the methods section of
    the related publication."
article_processing_charge: No
author:
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Anna M
  full_name: Andersson, Anna M
  id: 2B8A40DA-F248-11E8-B48F-1D18A9856A87
  last_name: Andersson
  orcid: 0000-0003-2912-6769
- first_name: Kathrin
  full_name: Tomasek, Kathrin
  id: 3AEC8556-F248-11E8-B48F-1D18A9856A87
  last_name: Tomasek
  orcid: 0000-0003-3768-877X
- first_name: Enrique
  full_name: Balleza, Enrique
  last_name: Balleza
- first_name: Daniel
  full_name: Kiviet, Daniel
  last_name: Kiviet
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Bergmiller T, Andersson AM, Tomasek K, et al. Biased partitioning of the multi-drug
    efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity. 2017. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:53">10.15479/AT:ISTA:53</a>
  apa: Bergmiller, T., Andersson, A. M., Tomasek, K., Balleza, E., Kiviet, D., Hauschild,
    R., … Guet, C. C. (2017). Biased partitioning of the multi-drug efflux pump AcrAB-TolC
    underlies long-lived phenotypic heterogeneity. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT:ISTA:53">https://doi.org/10.15479/AT:ISTA:53</a>
  chicago: Bergmiller, Tobias, Anna M Andersson, Kathrin Tomasek, Enrique Balleza,
    Daniel Kiviet, Robert Hauschild, Gašper Tkačik, and Calin C Guet. “Biased Partitioning
    of the Multi-Drug Efflux Pump AcrAB-TolC Underlies Long-Lived Phenotypic Heterogeneity.”
    Institute of Science and Technology Austria, 2017. <a href="https://doi.org/10.15479/AT:ISTA:53">https://doi.org/10.15479/AT:ISTA:53</a>.
  ieee: T. Bergmiller <i>et al.</i>, “Biased partitioning of the multi-drug efflux
    pump AcrAB-TolC underlies long-lived phenotypic heterogeneity.” Institute of Science
    and Technology Austria, 2017.
  ista: Bergmiller T, Andersson AM, Tomasek K, Balleza E, Kiviet D, Hauschild R, Tkačik
    G, Guet CC. 2017. Biased partitioning of the multi-drug efflux pump AcrAB-TolC
    underlies long-lived phenotypic heterogeneity, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:53">10.15479/AT:ISTA:53</a>.
  mla: Bergmiller, Tobias, et al. <i>Biased Partitioning of the Multi-Drug Efflux
    Pump AcrAB-TolC Underlies Long-Lived Phenotypic Heterogeneity</i>. Institute of
    Science and Technology Austria, 2017, doi:<a href="https://doi.org/10.15479/AT:ISTA:53">10.15479/AT:ISTA:53</a>.
  short: T. Bergmiller, A.M. Andersson, K. Tomasek, E. Balleza, D. Kiviet, R. Hauschild,
    G. Tkačik, C.C. Guet, (2017).
datarep_id: '53'
date_created: 2018-12-12T12:31:32Z
date_published: 2017-03-10T00:00:00Z
date_updated: 2025-09-11T07:05:03Z
day: '10'
ddc:
- '571'
department:
- _id: CaGu
- _id: GaTk
- _id: Bio
doi: 10.15479/AT:ISTA:53
file:
- access_level: open_access
  checksum: d77859af757ac8025c50c7b12b52eaf3
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:38Z
  date_updated: 2020-07-14T12:47:03Z
  file_id: '5603'
  file_name: IST-2017-53-v1+1_Data_MDE.zip
  file_size: 6773204
  relation: main_file
file_date_updated: 2020-07-14T12:47:03Z
has_accepted_license: '1'
keyword:
- single cell microscopy
- mother machine microfluidic device
- AcrAB-TolC pump
- multi-drug efflux
- Escherichia coli
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '03'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '665'
    relation: research_paper
    status: public
status: public
title: Biased partitioning of the multi-drug efflux pump AcrAB-TolC underlies long-lived
  phenotypic heterogeneity
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '5562'
abstract:
- lang: eng
  text: "This data was collected as part of the study [1]. It consists of preprocessed
    multi-electrode array recording from 160 salamander retinal ganglion cells responding
    to 297 repeats of a 19 s natural movie. The data is available in two formats:
    (1) a .mat file containing an array with dimensions “number of repeats” x “number
    of neurons” x “time in a repeat”; (2) a zipped .txt file containing the same data
    represented as an array with dimensions “number of neurons” x “number of samples”,
    where the number of samples is equal to the product of the number of repeats and
    timebins within a repeat. The time dimension is divided into 20 ms time windows,
    and the array is binary indicating whether a given cell elicited at least one
    spike in a given time window during a particular repeat. See the reference below
    for details regarding collection and preprocessing:\r\n\r\n[1] Tkačik G, Marre
    O, Amodei D, Schneidman E, Bialek W, Berry MJ II. Searching for Collective Behavior
    in a Large Network of Sensory Neurons. PLoS Comput Biol. 2014;10(1):e1003408."
article_processing_charge: No
author:
- first_name: Olivier
  full_name: Marre, Olivier
  last_name: Marre
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Dario
  full_name: Amodei, Dario
  last_name: Amodei
- first_name: Elad
  full_name: Schneidman, Elad
  last_name: Schneidman
- first_name: William
  full_name: Bialek, William
  last_name: Bialek
- first_name: Michael
  full_name: Berry, Michael
  last_name: Berry
citation:
  ama: Marre O, Tkačik G, Amodei D, Schneidman E, Bialek W, Berry M. Multi-electrode
    array recording from salamander retinal ganglion cells. 2017. doi:<a href="https://doi.org/10.15479/AT:ISTA:61">10.15479/AT:ISTA:61</a>
  apa: Marre, O., Tkačik, G., Amodei, D., Schneidman, E., Bialek, W., &#38; Berry,
    M. (2017). Multi-electrode array recording from salamander retinal ganglion cells.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:61">https://doi.org/10.15479/AT:ISTA:61</a>
  chicago: Marre, Olivier, Gašper Tkačik, Dario Amodei, Elad Schneidman, William Bialek,
    and Michael Berry. “Multi-Electrode Array Recording from Salamander Retinal Ganglion
    Cells.” Institute of Science and Technology Austria, 2017. <a href="https://doi.org/10.15479/AT:ISTA:61">https://doi.org/10.15479/AT:ISTA:61</a>.
  ieee: O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, and M. Berry, “Multi-electrode
    array recording from salamander retinal ganglion cells.” Institute of Science
    and Technology Austria, 2017.
  ista: Marre O, Tkačik G, Amodei D, Schneidman E, Bialek W, Berry M. 2017. Multi-electrode
    array recording from salamander retinal ganglion cells, Institute of Science and
    Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:61">10.15479/AT:ISTA:61</a>.
  mla: Marre, Olivier, et al. <i>Multi-Electrode Array Recording from Salamander Retinal
    Ganglion Cells</i>. Institute of Science and Technology Austria, 2017, doi:<a
    href="https://doi.org/10.15479/AT:ISTA:61">10.15479/AT:ISTA:61</a>.
  short: O. Marre, G. Tkačik, D. Amodei, E. Schneidman, W. Bialek, M. Berry, (2017).
datarep_id: '61'
date_created: 2018-12-12T12:31:33Z
date_published: 2017-02-27T00:00:00Z
date_updated: 2025-09-29T11:14:05Z
day: '27'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.15479/AT:ISTA:61
file:
- access_level: open_access
  checksum: e620eff260646f57b479a69492c8b765
  content_type: application/octet-stream
  creator: system
  date_created: 2018-12-12T13:03:04Z
  date_updated: 2020-07-14T12:47:03Z
  file_id: '5622'
  file_name: IST-2017-61-v1+1_bint_fishmovie32_100.mat
  file_size: 1336936
  relation: main_file
- access_level: open_access
  checksum: de83f9b81ea0aae3cddfc3ed982e0759
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:03:05Z
  date_updated: 2020-07-14T12:47:03Z
  file_id: '5623'
  file_name: IST-2017-61-v1+2_bint_fishmovie32_100.zip
  file_size: 1897543
  relation: main_file
file_date_updated: 2020-07-14T12:47:03Z
has_accepted_license: '1'
keyword:
- multi-electrode recording
- retinal ganglion cells
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '2257'
    relation: used_in_publication
    status: public
status: public
title: Multi-electrode array recording from salamander retinal ganglion cells
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
