[{"department":[{"_id":"JaBr"}],"title":"RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity","article_type":"original","PlanS_conform":"1","oa_version":"Published Version","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-01-12T10:13:56Z","publication_status":"epub_ahead","status":"public","doi":"10.1038/s41586-025-09852-9","scopus_import":"1","_id":"20963","ddc":["570"],"article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","language":[{"iso":"eng"}],"year":"2026","day":"07","date_created":"2026-01-08T07:57:17Z","oa":1,"author":[{"full_name":"Dmytrenko, Oleg","last_name":"Dmytrenko","first_name":"Oleg"},{"full_name":"Yuan, Biao","last_name":"Yuan","first_name":"Biao"},{"full_name":"Crosby, Kadin T.","first_name":"Kadin T.","last_name":"Crosby"},{"full_name":"Krebel, Max","first_name":"Max","last_name":"Krebel"},{"full_name":"Chen, Xiye","first_name":"Xiye","last_name":"Chen"},{"last_name":"Nowak","first_name":"Jakub S.","full_name":"Nowak, Jakub S."},{"last_name":"Chramiec-Głąbik","first_name":"Andrzej","full_name":"Chramiec-Głąbik, Andrzej"},{"full_name":"Filani, Bamidele","last_name":"Filani","first_name":"Bamidele"},{"last_name":"Gribling-Burrer","first_name":"Anne-Sophie","full_name":"Gribling-Burrer, Anne-Sophie"},{"full_name":"van der Toorn, Wiep","first_name":"Wiep","last_name":"van der Toorn"},{"first_name":"Max","last_name":"von Kleist","full_name":"von Kleist, Max"},{"last_name":"Achmedov","first_name":"Tatjana","full_name":"Achmedov, Tatjana"},{"last_name":"Smyth","first_name":"Redmond P.","full_name":"Smyth, Redmond P."},{"first_name":"Sebastian","last_name":"Glatt","full_name":"Glatt, Sebastian"},{"id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","orcid":"0000-0003-0456-0753","first_name":"Jack Peter Kelly","last_name":"Bravo","full_name":"Bravo, Jack Peter Kelly"},{"full_name":"Heinz, Dirk W.","first_name":"Dirk W.","last_name":"Heinz"},{"last_name":"Jackson","first_name":"Ryan N.","full_name":"Jackson, Ryan N."},{"first_name":"Chase L.","last_name":"Beisel","full_name":"Beisel, Chase L."}],"quality_controlled":"1","month":"01","abstract":[{"text":"In all domains of life, tRNAs mediate the transfer of genetic information from mRNAs to proteins. As their depletion suppresses translation and, consequently, viral replication, tRNAs represent long-standing and increasingly recognized targets of innate immunity1,2,3,4,5. Here we report Cas12a3 effector nucleases from type V CRISPR–Cas adaptive immune systems in bacteria that preferentially cleave tRNAs after recognition of target RNA. Cas12a3 orthologues belong to one of two previously unreported nuclease clades that exhibit RNA-mediated cleavage of non-target RNA, and are distinct from all other known type V systems. Through cell-based and biochemical assays and direct RNA sequencing, we demonstrate that recognition of a complementary target RNA by the CRISPR RNA triggers Cas12a3 to cleave the conserved 5′-CCA-3′ tail of diverse tRNAs to drive growth arrest and anti-phage defence. Cryogenic electron microscopy structures further revealed a distinct tRNA-loading domain that positions the tRNA tail in the RuvC active site of the nuclease. By designing synthetic reporters that mimic the tRNA acceptor stem and tail, we expanded the capacity of current CRISPR-based diagnostics for multiplexed RNA detection. Overall, these findings reveal widespread tRNA inactivation as a previously unrecognized CRISPR-based immune strategy that broadens the application space of the existing CRISPR toolbox.","lang":"eng"}],"citation":{"ista":"Dmytrenko O, Yuan B, Crosby KT, Krebel M, Chen X, Nowak JS, Chramiec-Głąbik A, Filani B, Gribling-Burrer A-S, van der Toorn W, von Kleist M, Achmedov T, Smyth RP, Glatt S, Bravo JPK, Heinz DW, Jackson RN, Beisel CL. 2026. RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity. Nature.","ama":"Dmytrenko O, Yuan B, Crosby KT, et al. RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity. <i>Nature</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41586-025-09852-9\">10.1038/s41586-025-09852-9</a>","mla":"Dmytrenko, Oleg, et al. “RNA-Triggered Cas12a3 Cleaves TRNA Tails to Execute Bacterial Immunity.” <i>Nature</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41586-025-09852-9\">10.1038/s41586-025-09852-9</a>.","short":"O. Dmytrenko, B. Yuan, K.T. Crosby, M. Krebel, X. Chen, J.S. Nowak, A. Chramiec-Głąbik, B. Filani, A.-S. Gribling-Burrer, W. van der Toorn, M. von Kleist, T. Achmedov, R.P. Smyth, S. Glatt, J.P.K. Bravo, D.W. Heinz, R.N. Jackson, C.L. Beisel, Nature (2026).","chicago":"Dmytrenko, Oleg, Biao Yuan, Kadin T. Crosby, Max Krebel, Xiye Chen, Jakub S. Nowak, Andrzej Chramiec-Głąbik, et al. “RNA-Triggered Cas12a3 Cleaves TRNA Tails to Execute Bacterial Immunity.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-025-09852-9\">https://doi.org/10.1038/s41586-025-09852-9</a>.","apa":"Dmytrenko, O., Yuan, B., Crosby, K. T., Krebel, M., Chen, X., Nowak, J. S., … Beisel, C. L. (2026). RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-09852-9\">https://doi.org/10.1038/s41586-025-09852-9</a>","ieee":"O. Dmytrenko <i>et al.</i>, “RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity,” <i>Nature</i>. Springer Nature, 2026."},"publication":"Nature","main_file_link":[{"url":"https://doi.org/10.1038/s41586-025-09852-9","open_access":"1"}],"pmid":1,"OA_place":"publisher","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"acknowledgement":"We thank Ł. Koziej for processing of the initial cryo-EM datasets, S. Schmelz for support in cryo-EM, A. Gatzemeier for assistance in the purification of dBa1Cas12a3, R. Rarose for support with the in vitro RNA experiments, M. Kaminski for providing purified PsmCas13b protein, L. Schönemann for protein purification, and C. Krempl and S. Backesfor providing the RSV and influenza A transcript-encoding plasmids. This work was supported through funding by the European Research Council (101001394 to S.G.; 865973 and 101158249 to C.L.B.), the R. Gaurth Hansen Family (to R.N.J.), the National Institutes of Health (R35GM138080 to R.N.J.), the PostDoc Plus Program from the Graduate School of Life Sciences at Julius-Maximilians-Universität Würzburg (to O.D.), and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy–The Berlin Mathematics Research Center MATH+ (EXC−2046/1, project ID: 390685689 to M.v.K.). Open access funding provided by Helmholtz-Zentrum für Infektionsforschung GmbH (HZI).","date_published":"2026-01-07T00:00:00Z","external_id":{"pmid":["41501459"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","has_accepted_license":"1"},{"arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","DOAJ_listed":"1","type":"journal_article","oa_version":"Published Version","PlanS_conform":"1","article_type":"original","title":"First constraints on the local ionization topology in front of two quasars at z ∼ 7.5","department":[{"_id":"ZoHa"}],"article_processing_charge":"Yes","language":[{"iso":"eng"}],"OA_type":"gold","ddc":["520"],"file":[{"relation":"main_file","file_size":2174272,"creator":"dernst","file_id":"20979","date_created":"2026-01-12T09:43:07Z","content_type":"application/pdf","success":1,"checksum":"68f04ab0fdcee4f12341d116c5f794cd","file_name":"2026_MonthNoticesRAS_Kist.pdf","date_updated":"2026-01-12T09:43:07Z","access_level":"open_access"}],"_id":"20974","intvolume":"       545","doi":"10.1093/mnras/staf2219","scopus_import":"1","status":"public","publication_status":"published","issue":"3","date_updated":"2026-01-12T09:45:54Z","month":"01","quality_controlled":"1","author":[{"full_name":"Kist, Timo","last_name":"Kist","first_name":"Timo"},{"last_name":"Hennawi","first_name":"Joseph F.","full_name":"Hennawi, Joseph F."},{"full_name":"Davies, Frederick B.","last_name":"Davies","first_name":"Frederick B."},{"full_name":"Bañados, Eduardo","last_name":"Bañados","first_name":"Eduardo"},{"last_name":"Bosman","first_name":"Sarah E.I.","full_name":"Bosman, Sarah E.I."},{"last_name":"Cai","first_name":"Zheng","full_name":"Cai, Zheng"},{"first_name":"Anna Christina","last_name":"Eilers","full_name":"Eilers, Anna Christina"},{"first_name":"Xiaohui","last_name":"Fan","full_name":"Fan, Xiaohui"},{"full_name":"Haiman, Zoltán","orcid":"0000-0003-3633-5403","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","first_name":"Zoltán"},{"last_name":"Jun","first_name":"Hyunsung D.","full_name":"Jun, Hyunsung D."},{"full_name":"Liu, Yichen","last_name":"Liu","first_name":"Yichen"},{"last_name":"Yang","first_name":"Jinyi","full_name":"Yang, Jinyi"},{"first_name":"Feige","last_name":"Wang","full_name":"Wang, Feige"}],"oa":1,"date_created":"2026-01-11T23:01:34Z","day":"01","article_number":"staf2219","year":"2026","volume":545,"has_accepted_license":"1","publisher":"Oxford University Press","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"We acknowledge helpful conversations with the ENIGMA group at UC Santa Barbara and Leiden University. This work is based on observations made with the NASA/ESA/CSA JWST. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programmes #1219 and #1764. This work made use of numpy (C. R. Harris et al. 2020), scipy (P. Virtanen et al. 2020), jax (J. Bradbury et al. 2018), numpyro (E. Bingham et al. 2018; D. Phan, N. Pradhan & M. Jankowiak 2019), sklearn (F. Pedregosa et al. 2011), astropy (Astropy Collaboration 2013, 2018, 2022), PypeIt (J. Prochaska et al. 2020), skycalc_ipy (K. Leschinski 2021), h5py (A. Collette 2013), matplotlib (J. D. Hunter 2007), corner.py (D. Foreman-Mackey 2016), and IPython (F. Pérez & B. E. Granger 2007). TK and JFH acknowledge support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 885301). JFH acknowledges support from NSF grant no. 2307180. SEIB was supported by the Deutsche Forschungsgemeinschaft (DFG) under Emmy Noether grant number BO 5771/1-1. FW acknowledges support from NSF award AST-2513040.","date_published":"2026-01-01T00:00:00Z","file_date_updated":"2026-01-12T09:43:07Z","external_id":{"arxiv":["2508.21818"]},"publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"OA_place":"publisher","publication":"Monthly Notices of the Royal Astronomical Society","citation":{"apa":"Kist, T., Hennawi, J. F., Davies, F. B., Bañados, E., Bosman, S. E. I., Cai, Z., … Wang, F. (2026). First constraints on the local ionization topology in front of two quasars at z ∼ 7.5. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staf2219\">https://doi.org/10.1093/mnras/staf2219</a>","short":"T. Kist, J.F. Hennawi, F.B. Davies, E. Bañados, S.E.I. Bosman, Z. Cai, A.C. Eilers, X. Fan, Z. Haiman, H.D. Jun, Y. Liu, J. Yang, F. Wang, Monthly Notices of the Royal Astronomical Society 545 (2026).","chicago":"Kist, Timo, Joseph F. Hennawi, Frederick B. Davies, Eduardo Bañados, Sarah E.I. Bosman, Zheng Cai, Anna Christina Eilers, et al. “First Constraints on the Local Ionization Topology in Front of Two Quasars at z ∼ 7.5.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/mnras/staf2219\">https://doi.org/10.1093/mnras/staf2219</a>.","ieee":"T. Kist <i>et al.</i>, “First constraints on the local ionization topology in front of two quasars at z ∼ 7.5,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 545, no. 3. Oxford University Press, 2026.","ista":"Kist T, Hennawi JF, Davies FB, Bañados E, Bosman SEI, Cai Z, Eilers AC, Fan X, Haiman Z, Jun HD, Liu Y, Yang J, Wang F. 2026. First constraints on the local ionization topology in front of two quasars at z ∼ 7.5. Monthly Notices of the Royal Astronomical Society. 545(3), staf2219.","mla":"Kist, Timo, et al. “First Constraints on the Local Ionization Topology in Front of Two Quasars at z ∼ 7.5.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 545, no. 3, staf2219, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/mnras/staf2219\">10.1093/mnras/staf2219</a>.","ama":"Kist T, Hennawi JF, Davies FB, et al. First constraints on the local ionization topology in front of two quasars at z ∼ 7.5. <i>Monthly Notices of the Royal Astronomical Society</i>. 2026;545(3). doi:<a href=\"https://doi.org/10.1093/mnras/staf2219\">10.1093/mnras/staf2219</a>"},"abstract":[{"text":"Thus far, Lyman-α damping wings towards quasars have been used to probe the global ionization state of the foreground intergalactic medium (IGM). A new parametrization has demonstrated that the damping wing signature also carries local information about the distribution of neutral hydrogen (H I) in front of the quasar before it started shining. Leveraging a recently introduced Bayesian JAX-based Hamiltonian Monte Carlo inference framework, we derive constraints on the Lorentzian-weighted H I column density NDW H I , the quasar’s distance rpatch to the first neutral patch, and its lifetime tQ based on James Webb Space\r\nTelescope (JWST) Near Infrared Spectrograph (NIRSpec) spectra of the two z ∼ 7.5 quasars J1007+2115 and J1342+0928. After folding in model-dependent topology information, we find that J1007+2115 (and J1342+0928) is most likely to reside in a (xH1)= 0.32+0.22 −0.20 (0.58+0.23 −0.23) neutral IGM while shining for a remarkably short lifetime of log10 tQ/yr = 4.14+0.74 −0.18 (an intermediate lifetime of 5.64+0.25 −0.43) along a sightline with log10 NDW\r\nH I /cm−2 = 19.70+0.35 −0.86 (20.24+0.25 −0.22) and rpatch = 28.9+54.0 −14.4 cMpc\r\n(10.9+5.6−5.9 cMpc). In light of the potential presence of local absorbers in the foreground of J1342+0928 as has been recently suggested, we also demonstrate how the Lorentzian-weighted column density NDW H I provides a natural means for quantifying their contribution to the observed damping wing signal.","lang":"eng"}]},{"citation":{"ieee":"T. K. Dey, A. Haas, and M. Lipiński, “Computing a connection matrix and persistence efficiently from a morse decomposition,” <i>SIAM Journal on Applied Dynamical Systems</i>, vol. 25, no. 1. Society for Industrial &#38; Applied Mathematics, pp. 108–130, 2026.","chicago":"Dey, Tamal K., Andrew Haas, and Michał Lipiński. “Computing a Connection Matrix and Persistence Efficiently from a Morse Decomposition.” <i>SIAM Journal on Applied Dynamical Systems</i>. Society for Industrial &#38; Applied Mathematics, 2026. <a href=\"https://doi.org/10.1137/25m1739406\">https://doi.org/10.1137/25m1739406</a>.","short":"T.K. Dey, A. Haas, M. Lipiński, SIAM Journal on Applied Dynamical Systems 25 (2026) 108–130.","apa":"Dey, T. K., Haas, A., &#38; Lipiński, M. (2026). Computing a connection matrix and persistence efficiently from a morse decomposition. <i>SIAM Journal on Applied Dynamical Systems</i>. Society for Industrial &#38; Applied Mathematics. <a href=\"https://doi.org/10.1137/25m1739406\">https://doi.org/10.1137/25m1739406</a>","ama":"Dey TK, Haas A, Lipiński M. Computing a connection matrix and persistence efficiently from a morse decomposition. <i>SIAM Journal on Applied Dynamical Systems</i>. 2026;25(1):108-130. doi:<a href=\"https://doi.org/10.1137/25m1739406\">10.1137/25m1739406</a>","mla":"Dey, Tamal K., et al. “Computing a Connection Matrix and Persistence Efficiently from a Morse Decomposition.” <i>SIAM Journal on Applied Dynamical Systems</i>, vol. 25, no. 1, Society for Industrial &#38; Applied Mathematics, 2026, pp. 108–30, doi:<a href=\"https://doi.org/10.1137/25m1739406\">10.1137/25m1739406</a>.","ista":"Dey TK, Haas A, Lipiński M. 2026. Computing a connection matrix and persistence efficiently from a morse decomposition. SIAM Journal on Applied Dynamical Systems. 25(1), 108–130."},"abstract":[{"lang":"eng","text":"Morse decompositions partition the flows in a vector field into equivalent structures. Given such a decomposition, one can define a further summary of its flow structure by what is called a connection matrix. These matrices, a generalization of Morse boundary operators from classical Morse theory, capture the connections made by the flows among the critical structures—such as attractors, repellers, and orbits—in a vector field. Recently, in the context of combinatorial dynamics, an efficient persistence-like algorithm to compute connection matrices has been proposed in Dey, Lipiński, Mrozek, and Slechta [SIAM J. Appl. Dyn. Syst., 23 (2024), pp. 81–97]. We show that, actually, the classical persistence algorithm with exhaustive reduction retrieves connection matrices, both simplifying the algorithm of Dey et al. and bringing the theory of persistence closer to combinatorial dynamical systems. We supplement this main result with an observation: the concept of persistence as defined for scalar fields naturally adapts to Morse decompositions whose Morse sets are filtered with a Lyapunov function. We conclude by presenting preliminary experimental results."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2502.19369"}],"publication":"SIAM Journal on Applied Dynamical Systems","acknowledgement":"This research was supported by NSF grants DMS-2301360 and CCF-2437030 as well as from the European Union's Horizon 2020 research and innovation programme under Marie Sk\\lodowska-Curie grant 101034413.\r\n","date_published":"2026-01-01T00:00:00Z","external_id":{"arxiv":["2502.19369"]},"OA_place":"repository","publication_identifier":{"issn":["1536-0040"]},"publisher":"Society for Industrial & Applied Mathematics","volume":25,"date_created":"2026-01-12T11:17:06Z","day":"01","year":"2026","oa":1,"month":"01","quality_controlled":"1","author":[{"full_name":"Dey, Tamal K.","last_name":"Dey","first_name":"Tamal K."},{"last_name":"Haas","first_name":"Andrew","full_name":"Haas, Andrew"},{"last_name":"Lipiński","first_name":"Michał","orcid":"0000-0001-9789-9750","id":"dfffb474-4317-11ee-8f5c-fe3fc95a425e","full_name":"Lipiński, Michał"}],"status":"public","publication_status":"published","issue":"1","date_updated":"2026-01-20T07:40:39Z","intvolume":"        25","doi":"10.1137/25m1739406","scopus_import":"1","language":[{"iso":"eng"}],"OA_type":"green","article_processing_charge":"No","ddc":["510"],"_id":"20980","title":"Computing a connection matrix and persistence efficiently from a morse decomposition","department":[{"_id":"HeEd"}],"type":"journal_article","oa_version":"Preprint","article_type":"original","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"ec_funded":1,"arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"108-130"},{"doi":"10.1016/j.cub.2025.12.025","scopus_import":"1","date_updated":"2026-01-20T07:33:32Z","status":"public","publication_status":"epub_ahead","ddc":["570","577"],"_id":"20986","OA_type":"hybrid","language":[{"iso":"eng"}],"article_processing_charge":"Yes (in subscription journal)","article_type":"original","type":"journal_article","PlanS_conform":"1","oa_version":"Published Version","department":[{"_id":"GradSch"},{"_id":"TiVo"}],"title":"Interplay between syllable duration and pitch during whistle matching in wild nightingales","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ec_funded":1,"project":[{"call_identifier":"H2020","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning.","grant_number":"819603","_id":"0aacfa84-070f-11eb-9043-d7eb2c709234"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.cub.2025.12.025","open_access":"1"}],"publication":"Current Biology","abstract":[{"lang":"eng","text":"During complex vocal interactions, different features of acoustic stimuli are integrated to produce appropriate vocal responses,1 such as copying sounds during vocal matching behavior in some animals.2,3,4,5,6,7,8,9,10,11,12 However, little is known about the interplay and possible trade-offs between the different temporal and spectral acoustic features during these vocal exchanges.2,13,14 Nightingales can flexibly match the pitch of their tonal “whistle songs” in real time during counter-singing duels.15,16 Here, we show that the syllable duration of whistle playbacks could alter the song responses of wild nightingales, causing their whistle duration distribution to shift toward the presented stimulus duration. When exposed to whistle playbacks featuring unnatural combinations of pitch and duration, nightingales demonstrate a flexible trade-off between pitch matching and temporal imitation, yet they are constrained by their vocal repertoire. They selectively adapted their vocal responses to approximate these novel stimuli, aligning them with their natural whistle repertoire. We developed a computational model of nightingale whistle-matching behavior that revealed a hierarchical organization of acoustic feature production. During whistle matching, the feature integration process is constrained by the duration of syllables, and pitch matching follows within this temporal framework, forcing a trade-off between the two features. Our findings reveal a complex interplay between the spectral and temporal domains that shapes song-matching behavior."}],"citation":{"ista":"Calderon Garcia JS, Costalunga G, Vogels TP, Vallentin D. 2026. Interplay between syllable duration and pitch during whistle matching in wild nightingales. Current Biology.","ama":"Calderon Garcia JS, Costalunga G, Vogels TP, Vallentin D. Interplay between syllable duration and pitch during whistle matching in wild nightingales. <i>Current Biology</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">10.1016/j.cub.2025.12.025</a>","mla":"Calderon Garcia, Juan Sebastian, et al. “Interplay between Syllable Duration and Pitch during Whistle Matching in Wild Nightingales.” <i>Current Biology</i>, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">10.1016/j.cub.2025.12.025</a>.","short":"J.S. Calderon Garcia, G. Costalunga, T.P. Vogels, D. Vallentin, Current Biology (2026).","chicago":"Calderon Garcia, Juan Sebastian, Giacomo Costalunga, Tim P Vogels, and Daniela Vallentin. “Interplay between Syllable Duration and Pitch during Whistle Matching in Wild Nightingales.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">https://doi.org/10.1016/j.cub.2025.12.025</a>.","apa":"Calderon Garcia, J. S., Costalunga, G., Vogels, T. P., &#38; Vallentin, D. (2026). Interplay between syllable duration and pitch during whistle matching in wild nightingales. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">https://doi.org/10.1016/j.cub.2025.12.025</a>","ieee":"J. S. Calderon Garcia, G. Costalunga, T. P. Vogels, and D. Vallentin, “Interplay between syllable duration and pitch during whistle matching in wild nightingales,” <i>Current Biology</i>. Elsevier, 2026."},"publisher":"Elsevier","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"has_accepted_license":"1","acknowledgement":"We would like to thank J. Benichov and N. Hein for their help with fieldwork; M. Ramadas for helping with the segmentation analysis; T. Eliav, C. Chintaluri, G. Tkacik, and A. Navas for providing helpful comments to the project and manuscript; and A. Costalunga for the drawings of nightingales. Funding sources: The Joachim Herz Stiftung Add-on Fellowships for Interdisciplinary Life Science, awarded to G.C.; the ERC Consolidator Grant 819603 SYNAPSEEK, awarded to T.P.V.; and DFG Research Unit 5768–532521431, DFG Research Grant-547921981, DFG SFB 1315–327654276, and the ERC Starting Grant 757459 MIDNIGHT, awarded to D.V.","date_published":"2026-01-12T00:00:00Z","publication_identifier":{"issn":["0960-9822"],"eissn":["1879-0445"]},"OA_place":"publisher","day":"12","year":"2026","date_created":"2026-01-14T12:00:29Z","quality_controlled":"1","author":[{"full_name":"Calderon Garcia, Juan Sebastian","id":"1271b54b-dbcd-11ea-9d1d-d92da838fe2c","first_name":"Juan Sebastian","last_name":"Calderon Garcia"},{"full_name":"Costalunga, Giacomo","last_name":"Costalunga","first_name":"Giacomo"},{"last_name":"Vogels","first_name":"Tim P","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","orcid":"0000-0003-3295-6181","full_name":"Vogels, Tim P"},{"last_name":"Vallentin","first_name":"Daniela","full_name":"Vallentin, Daniela"}],"month":"01","oa":1},{"abstract":[{"lang":"eng","text":"Rapid local adaptation to new environments is critical for species persistence, especially in introduced populations. The evolutionary success of these populations is fundamentally dictated by the organization of genetic variation—the genomic architecture—in the face of severe demographic constraints, such as the founder effects and genetic bottlenecks that frequently accompany colonization. A central question in evolutionary biology is whether rapid adaptation relies on major-effect loci, such as chromosomal inversions, or on many small-effect loci dispersed across the genome. Furthermore, the genomic architecture strongly influences the extent to which evolutionary outcomes are predictable. Using introduced populations of the marine snail, Littorina saxatilis, as a model, this thesis investigates how genetic variation and genomic structure drive adaptation following introduction. We employed a population genomics approach on experimentally and accidentally introduced populations to dissect the specific genomic features that underpin divergence in newly colonized environments.\r\n\r\nIn Chapter 2, we tested the predictability of local adaptation through an uncommon 30-year transplant experiment in nature. By distinguishing allele and chromosomal inversion frequency changes from neutral expectations, we found that evolutionary change was highly predictable at the macro-scale (phenotypes and chromosomal inversions), but less robust at the level of individual collinear loci. This result demonstrates that evolution can be predictable when a population possesses sufficient standing genetic variation (SGV), with chromosomal inversions acting as key integrated units that facilitate a rapid response to selection. Building on this, Chapter 3 applied whole-genome sequencing to three accidentally introduced populations (Venice, San Francisco, and Redwood City) to investigate their likely source and genomic patterns of divergence. We identified genomic regions of remarkable divergence potentially associated with local adaptation, and likely fuelled by SGV, while explicitly acknowledging the difficulty in disentangling selection signals from the genome-wide effects of demographic processes. Furthermore, we found that the divergence patterns relied extensively on the collinear genome in these introduced populations, and less clearly on the chromosomal inversions. This observation contrasts with local adaptation observed in the experimental system that relied on both collinear loci and highly selected chromosomal inversions, highlighting how demographic history and genomic architecture influence the detectable signature of local adaptation.\r\n\r\nA major limitation to conducting large-scale comparative evolutionary studies is the lack of data standardization, which prevents the integration of community knowledge and high-resolution environmental and genetic data. Chapter 4 addresses this by developing a community database for the Littorina system. This platform implements standardized protocols for the integration of diverse phenotypic and environmental data from multiple Littorina species. Likewise, the platform also centralizes the availability of associated genomic data through links to external repositories. This database represents a crucial tool to test complex, large-scale evolutionary hypotheses.\r\n\r\nCollectively, this thesis strongly reinforces the fundamental importance of SGV as the raw material for successful local adaptation, a conclusion supported by evidence in both experimental and accidental introductions. Furthermore, this work highlights the critical role of the genomic architecture—specifically chromosomal inversions—in driving the predictability and effectiveness of adaptive responses. Our findings underscore how the interplay between SGV and genomic architecture dictates the trajectory and detectability of evolution in colonizing populations, while simultaneously providing a necessary tool to advance comparative evolutionary genomics in emerging model organisms."}],"corr_author":"1","citation":{"ieee":"D. F. Garcia Castillo, “The genomic architecture of local adaptation in introduced populations,” Institute of Science and Technology Austria, 2026.","short":"D.F. Garcia Castillo, The Genomic Architecture of Local Adaptation in Introduced Populations, Institute of Science and Technology Austria, 2026.","chicago":"Garcia Castillo, Diego Fernando. “The Genomic Architecture of Local Adaptation in Introduced Populations.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-20991\">https://doi.org/10.15479/AT-ISTA-20991</a>.","apa":"Garcia Castillo, D. F. (2026). <i>The genomic architecture of local adaptation in introduced populations</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20991\">https://doi.org/10.15479/AT-ISTA-20991</a>","ama":"Garcia Castillo DF. The genomic architecture of local adaptation in introduced populations. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20991\">10.15479/AT-ISTA-20991</a>","mla":"Garcia Castillo, Diego Fernando. <i>The Genomic Architecture of Local Adaptation in Introduced Populations</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20991\">10.15479/AT-ISTA-20991</a>.","ista":"Garcia Castillo DF. 2026. The genomic architecture of local adaptation in introduced populations. Institute of Science and Technology Austria."},"file_date_updated":"2026-01-16T13:08:59Z","acknowledgement":"I acknowledge the funding agencies 1Norwegian Research Council RCN project 315287.\r\n2The FIASCO project \"Illuminating range shifts through evolutionary FIASCO: contrasting\r\nFaIling And Successful ColOnizations in replicated wild populations\", funded by the\r\nEuropean Union - Next Generation EU (Piano Nazionale di Ripresa e Resilienza - MUR\r\ncode: P202229JBC, CUP: C53D23007100001). 3Ecotypic formation in Littorina saxatilis\r\nin the Western Atlantic and comparisons across the North Atlantic. University of\r\nGothenburg Research Travel Grant, Tjarno Marine Laboratory, Sweden. $3023 (2018).\r\n4JIN project (Young Researchers, Spanish Ministry of Science, RTI2018-101274-J-I00)","date_published":"2026-01-16T00:00:00Z","OA_place":"publisher","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-077-0"]},"publisher":"Institute of Science and Technology Austria","tmp":{"short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png"},"has_accepted_license":"1","day":"16","year":"2026","alternative_title":["ISTA Thesis"],"date_created":"2026-01-16T09:47:59Z","oa":1,"author":[{"full_name":"Garcia Castillo, Diego Fernando","id":"ae681a14-dc74-11ea-a0a7-c6ef18161701","last_name":"Garcia Castillo","first_name":"Diego Fernando"}],"related_material":{"record":[{"status":"public","id":"18498","relation":"research_data"},{"relation":"part_of_dissertation","id":"18491","status":"public"}]},"month":"01","date_updated":"2026-04-16T12:20:37Z","status":"public","publication_status":"published","doi":"10.15479/AT-ISTA-20991","degree_awarded":"PhD","ddc":["576"],"_id":"20991","file":[{"date_updated":"2026-01-16T12:25:13Z","access_level":"closed","checksum":"841f1bc073d667125729b2a017f8c37a","file_name":"2026_Garcia_Diego_Thesis.docx","date_created":"2026-01-16T12:25:13Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"20996","creator":"dgarciac","relation":"source_file","file_size":22456421},{"file_id":"20997","creator":"dgarciac","relation":"main_file","file_size":9556719,"checksum":"a1f33d4f183ce7072eee42a6ccf5340b","file_name":"2026_Garcia_Diego_Thesis.pdf","date_updated":"2026-01-16T12:25:13Z","access_level":"open_access","date_created":"2026-01-16T12:25:13Z","content_type":"application/pdf","success":1},{"checksum":"98a80691067174c30fe53f38ce7344e6","file_name":"2026_DiegoGarcia_LittorinaDB Source Code and Protocols.rar","date_updated":"2026-01-16T13:08:14Z","access_level":"closed","date_created":"2026-01-16T13:08:14Z","content_type":"application/x-compressed","description":"Source code of the PostgreSQL database, front-end and back-end of the LittorinaDB web application developed as a product of the 4th chapter of the thesis.","creator":"dgarciac","file_id":"20998","file_size":54491433,"relation":"supplementary_material"},{"access_level":"open_access","date_updated":"2026-01-16T13:08:14Z","file_name":"2026_DiegoGarcia_Thesis-Supplementary_Material.rar","checksum":"99a3cab2fa36666b9a92eefc27d586da","content_type":"application/x-compressed","date_created":"2026-01-16T13:08:14Z","file_id":"20999","creator":"dgarciac","file_size":7982811,"relation":"supplementary_material"},{"date_created":"2026-01-16T13:08:59Z","content_type":"text/plain","date_updated":"2026-01-16T13:08:59Z","access_level":"open_access","checksum":"255fdf56b2932c46bf27c63aa6106a4f","file_name":"README.txt","file_size":732,"relation":"supplementary_material","creator":"dgarciac","file_id":"21000"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"supervisor":[{"orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H"},{"first_name":"Anja M","last_name":"Westram","id":"3C147470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1050-4969","full_name":"Westram, Anja M"}],"department":[{"_id":"GradSch"},{"_id":"NiBa"}],"title":"The genomic architecture of local adaptation in introduced populations","type":"dissertation","oa_version":"Published Version","page":"199","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd"},{"PlanS_conform":"1","oa_version":"Published Version","type":"journal_article","article_type":"original","title":"A polyhedral structure controls programmable self-assembly","department":[{"_id":"CaGo"},{"_id":"GradSch"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","project":[{"grant_number":"FTI23-G-011","name":"Dynamically reconfigurable self-assembly with triangular DNA-origami bricks","_id":"8dd93da8-16d5-11f0-9cad-d2c70200d9a5"}],"doi":"10.1038/s41567-025-03120-3","scopus_import":"1","publication_status":"epub_ahead","status":"public","date_updated":"2026-04-28T11:56:45Z","article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","language":[{"iso":"eng"}],"_id":"21006","ddc":["570","540"],"date_created":"2026-01-20T10:02:19Z","year":"2026","day":"08","month":"01","author":[{"id":"5eb8629e-15b2-11ec-abd3-e6f3e5e01f32","first_name":"Maximilian","last_name":"Hübl","full_name":"Hübl, Maximilian"},{"last_name":"Videbæk","first_name":"Thomas E.","full_name":"Videbæk, Thomas E."},{"full_name":"Hayakawa, Daichi","last_name":"Hayakawa","first_name":"Daichi"},{"full_name":"Rogers, W. Benjamin","first_name":"W. Benjamin","last_name":"Rogers"},{"full_name":"Goodrich, Carl Peter","id":"EB352CD2-F68A-11E9-89C5-A432E6697425","orcid":"0000-0002-1307-5074","first_name":"Carl Peter","last_name":"Goodrich"}],"related_material":{"link":[{"description":"News on ISTA website","url":"https://ista.ac.at/en/news/behind-natures-blueprints/","relation":"press_release"}]},"quality_controlled":"1","oa":1,"publication":"Nature Physics","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41567-025-03120-3"}],"citation":{"apa":"Hübl, M., Videbæk, T. E., Hayakawa, D., Rogers, W. B., &#38; Goodrich, C. P. (2026). A polyhedral structure controls programmable self-assembly. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03120-3\">https://doi.org/10.1038/s41567-025-03120-3</a>","chicago":"Hübl, Maximilian, Thomas E. Videbæk, Daichi Hayakawa, W. Benjamin Rogers, and Carl Peter Goodrich. “A Polyhedral Structure Controls Programmable Self-Assembly.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03120-3\">https://doi.org/10.1038/s41567-025-03120-3</a>.","short":"M. Hübl, T.E. Videbæk, D. Hayakawa, W.B. Rogers, C.P. Goodrich, Nature Physics (2026).","ieee":"M. Hübl, T. E. Videbæk, D. Hayakawa, W. B. Rogers, and C. P. Goodrich, “A polyhedral structure controls programmable self-assembly,” <i>Nature Physics</i>. Springer Nature, 2026.","ista":"Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. 2026. A polyhedral structure controls programmable self-assembly. Nature Physics.","mla":"Hübl, Maximilian, et al. “A Polyhedral Structure Controls Programmable Self-Assembly.” <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41567-025-03120-3\">10.1038/s41567-025-03120-3</a>.","ama":"Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. A polyhedral structure controls programmable self-assembly. <i>Nature Physics</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41567-025-03120-3\">10.1038/s41567-025-03120-3</a>"},"corr_author":"1","abstract":[{"lang":"eng","text":"Modern experimental methods in programmable self-assembly make it possible to precisely design particle concentrations, shapes and interactions. However, more physical insight is needed before we can take full advantage of this vast design space to assemble nanostructures with complex form and function. Here we show how a substantial part of this design space can be quickly and comprehensively understood by identifying a class of thermodynamic constraints that act on it. These thermodynamic constraints form a high-dimensional convex polyhedron that determines which nanostructures can be assembled at high equilibrium yield and reveals limitations that govern the coexistence of structures. We validate our predictions through detailed, quantitative assembly experiments of nanoscale particles synthesized using DNA origami. Our results uncover physical relationships underpinning many-component programmable self-assembly in equilibrium and form the basis for robust inverse design, applicable to various systems from biological protein complexes to synthetic nanomachines."}],"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"OA_place":"publisher","date_published":"2026-01-08T00:00:00Z","acknowledgement":"We thank B. Isaac and A. Tiano for their technical support with the electron microscopy and S. Waitukaitis for helpful comments on the manuscript. The TEM images were prepared and imaged at the Brandeis Electron Microscopy facility. This work was supported by the Gesellschaft für Forschungsförderung Niederösterreich under project FTI23-G-011 (M.C.H. and C.P.G.), the Brandeis University Materials Research Science and Engineering Center (MRSEC) under grant number NSF DMR-2011846 (T.E.V., D.H. and W.B.R.) and the Smith Family Foundation (W.B.R.). Open access funding provided by Institute of Science and Technology (IST Austria)."},{"project":[{"_id":"8f1d607d-16d5-11f0-9cad-ab453295ba5e","grant_number":"PAT 1250924","name":"Photoactive ligands for transformative nickel catalysis"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"866-881","title":"Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings","department":[{"_id":"BaPi"},{"_id":"GradSch"}],"type":"journal_article","PlanS_conform":"1","oa_version":"Published Version","article_type":"original","language":[{"iso":"eng"}],"OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","ddc":["540"],"file":[{"success":1,"date_created":"2026-01-21T09:12:10Z","content_type":"application/pdf","date_updated":"2026-01-21T09:12:10Z","access_level":"open_access","checksum":"05743d6d7b4bae37aad1a91471123032","file_name":"2026_ACSCatalysis_Bena.pdf","relation":"main_file","file_size":3797064,"creator":"dernst","file_id":"21030"}],"_id":"21008","status":"public","publication_status":"published","issue":"2","date_updated":"2026-01-21T09:15:16Z","intvolume":"        16","scopus_import":"1","doi":"10.1021/acscatal.5c07964","oa":1,"month":"01","quality_controlled":"1","author":[{"full_name":"Bena, Aleksander","first_name":"Aleksander","last_name":"Bena","id":"4197c39e-e8ec-11ed-86cb-afed934cd664"},{"full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","first_name":"Bartholomäus","last_name":"Pieber"}],"volume":16,"date_created":"2026-01-20T10:04:57Z","day":"16","year":"2026","file_date_updated":"2026-01-21T09:12:10Z","date_published":"2026-01-16T00:00:00Z","acknowledgement":"We gratefully acknowledge the Institute of Science and Technology Austria for generous financial support. B.P. acknowledges the Austrian Science Fund (PAT 1250924) for funding.","publication_identifier":{"eissn":["2155-5435"]},"OA_place":"publisher","has_accepted_license":"1","publisher":"American Chemical Society","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"citation":{"ama":"Bena A, Pieber B. Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. <i>ACS Catalysis</i>. 2026;16(2):866-881. doi:<a href=\"https://doi.org/10.1021/acscatal.5c07964\">10.1021/acscatal.5c07964</a>","mla":"Bena, Aleksander, and Bartholomäus Pieber. “Advances in NiI/NiIII-Catalyzed C(Sp2)–Heteroatom Cross-Couplings.” <i>ACS Catalysis</i>, vol. 16, no. 2, American Chemical Society, 2026, pp. 866–81, doi:<a href=\"https://doi.org/10.1021/acscatal.5c07964\">10.1021/acscatal.5c07964</a>.","ista":"Bena A, Pieber B. 2026. Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. ACS Catalysis. 16(2), 866–881.","ieee":"A. Bena and B. Pieber, “Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings,” <i>ACS Catalysis</i>, vol. 16, no. 2. American Chemical Society, pp. 866–881, 2026.","short":"A. Bena, B. Pieber, ACS Catalysis 16 (2026) 866–881.","chicago":"Bena, Aleksander, and Bartholomäus Pieber. “Advances in NiI/NiIII-Catalyzed C(Sp2)–Heteroatom Cross-Couplings.” <i>ACS Catalysis</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acscatal.5c07964\">https://doi.org/10.1021/acscatal.5c07964</a>.","apa":"Bena, A., &#38; Pieber, B. (2026). Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. <i>ACS Catalysis</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acscatal.5c07964\">https://doi.org/10.1021/acscatal.5c07964</a>"},"abstract":[{"text":"C(sp2)–heteroatom couplings operating via NiI/NiIII catalysis have emerged as an alternative to canonical Pd0/PdII systems that require complex ligand architectures. Despite intensive research efforts during the past decade, catalytic methods employing this approach are still mostly confined to activated starting materials and require high catalyst loadings due to the low catalytic activity of NiI and undesired catalyst deactivation events. This article highlights recent advances in the field toward solving these long-standing challenges. We survey strategies that streamline the generation of catalytically competent NiI species from bench-stable NiII precatalysts, and discuss mechanistic studies that shed light on deactivation pathways and the rate-determining oxidative addition of aryl halides. In the final section, we highlight recently developed synthetic methodologies, which provide evidence that limitations can indeed be addressed by working at elevated temperatures, employing alternative electrophiles, harnessing the benefits of additives, or fine-tuning the metal’s reactivity through the ligand field.","lang":"eng"}],"corr_author":"1","publication":"ACS Catalysis"},{"OA_place":"publisher","publication_identifier":{"eissn":["2469-9934"],"issn":["2469-9926"]},"file_date_updated":"2026-01-21T09:04:48Z","date_published":"2026-01-12T00:00:00Z","acknowledgement":"We thank G. M. Koutentakis, S. Wimberger, J. G. E. Harris, T. Enss, and A. Ghazaryan for fruitful discussions. M.L. acknowledges support by the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). R.-J.S. acknowledges funding from a EPSRC ERC underwrite (Grant No. EP/X025829/1), a EPSRC New Investigator Award (Grant No. EP/W00187X/1), and Trinity College, Cambridge. F.N.Ü. acknowledges support from the Marie Skłodowska-Curie Programme of the European Commission (Grant No. 893915), a Simons Investigator Award (Grant No. 511029), Trinity College Cambridge, and the Royal Society (Grant No. URF/R1/241667).","external_id":{"arxiv":["2408.16848"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"American Physical Society","has_accepted_license":"1","corr_author":"1","abstract":[{"text":"We demonstrate that periodically driven quantum rotors provide a promising and broadly applicable platform to implement multigap topological phases, where groups of bands can acquire topological invariants due to non-Abelian braiding of band degeneracies. By adiabatically varying the periodic kicks to the rotor we find nodal-line braiding, which causes sign flips of topological charges of band nodes and can prevent them from annihilating, indicated by nonzero values of the patch Euler class. In particular, we report on the emergence of an anomalous Dirac string phase arising in the strongly driven regime, a truly out-of-equilibrium phase of the quantum rotor. This phase emanates from braiding processes involving all (quasienergy) gaps and manifests itself with edge states at zero angular momentum. Our results reveal direct applications in state-of-the-art experiments of quantum rotors, such as linear molecules driven by periodic far-off-resonant laser pulses or artificial quantum rotors in optical lattices, whose extensive versatility offers precise modification and observation of novel non-Abelian topological properties.","lang":"eng"}],"citation":{"ama":"Karle V, Lemeshko M, Bouhon A, Slager R-J, Ünal FN. Anomalous multigap topological phases in periodically driven quantum rotors. <i>Physical Review A</i>. 2026;113(1). doi:<a href=\"https://doi.org/10.1103/db9d-9bns\">10.1103/db9d-9bns</a>","mla":"Karle, Volker, et al. “Anomalous Multigap Topological Phases in Periodically Driven Quantum Rotors.” <i>Physical Review A</i>, vol. 113, no. 1, 012216, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/db9d-9bns\">10.1103/db9d-9bns</a>.","ista":"Karle V, Lemeshko M, Bouhon A, Slager R-J, Ünal FN. 2026. Anomalous multigap topological phases in periodically driven quantum rotors. Physical Review A. 113(1), 012216.","ieee":"V. Karle, M. Lemeshko, A. Bouhon, R.-J. Slager, and F. N. Ünal, “Anomalous multigap topological phases in periodically driven quantum rotors,” <i>Physical Review A</i>, vol. 113, no. 1. American Physical Society, 2026.","chicago":"Karle, Volker, Mikhail Lemeshko, Adrien Bouhon, Robert-Jan Slager, and F. Nur Ünal. “Anomalous Multigap Topological Phases in Periodically Driven Quantum Rotors.” <i>Physical Review A</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/db9d-9bns\">https://doi.org/10.1103/db9d-9bns</a>.","short":"V. Karle, M. Lemeshko, A. Bouhon, R.-J. Slager, F.N. Ünal, Physical Review A 113 (2026).","apa":"Karle, V., Lemeshko, M., Bouhon, A., Slager, R.-J., &#38; Ünal, F. N. (2026). Anomalous multigap topological phases in periodically driven quantum rotors. <i>Physical Review A</i>. American Physical Society. <a href=\"https://doi.org/10.1103/db9d-9bns\">https://doi.org/10.1103/db9d-9bns</a>"},"publication":"Physical Review A","oa":1,"author":[{"first_name":"Volker","last_name":"Karle","id":"D7C012AE-D7ED-11E9-95E8-1EC5E5697425","orcid":"0000-0002-6963-0129","full_name":"Karle, Volker"},{"full_name":"Lemeshko, Mikhail","last_name":"Lemeshko","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802"},{"last_name":"Bouhon","first_name":"Adrien","full_name":"Bouhon, Adrien"},{"full_name":"Slager, Robert-Jan","first_name":"Robert-Jan","last_name":"Slager"},{"full_name":"Ünal, F. Nur","last_name":"Ünal","first_name":"F. Nur"}],"quality_controlled":"1","month":"01","volume":113,"year":"2026","article_number":"012216","day":"12","date_created":"2026-01-20T10:06:07Z","file":[{"checksum":"ca62a5050a234c0554e2583b1c126057","file_name":"2026_PhysicalReviewA_Karle.pdf","date_updated":"2026-01-21T09:04:48Z","access_level":"open_access","date_created":"2026-01-21T09:04:48Z","content_type":"application/pdf","success":1,"file_id":"21029","creator":"dernst","relation":"main_file","file_size":2650256}],"_id":"21009","ddc":["530"],"article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","language":[{"iso":"eng"}],"date_updated":"2026-03-16T12:21:55Z","publication_status":"published","issue":"1","status":"public","scopus_import":"1","doi":"10.1103/db9d-9bns","intvolume":"       113","ec_funded":1,"project":[{"_id":"2688CF98-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"801770","name":"Angulon: physics and applications of a new quasiparticle"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"department":[{"_id":"MiLe"}],"title":"Anomalous multigap topological phases in periodically driven quantum rotors","article_type":"original","oa_version":"Published Version","PlanS_conform":"1","type":"journal_article"},{"_id":"21012","file":[{"relation":"main_file","file_size":2623108,"creator":"dernst","file_id":"21028","success":1,"date_created":"2026-01-21T08:52:07Z","content_type":"application/pdf","date_updated":"2026-01-21T08:52:07Z","access_level":"open_access","checksum":"d909a9091c254b2d18ba014124663f69","file_name":"2026_CommACM_Barrett.pdf"}],"ddc":["000"],"OA_type":"hybrid","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","date_updated":"2026-01-21T08:55:24Z","publication_status":"published","issue":"1","status":"public","scopus_import":"1","doi":"10.1145/3737447","intvolume":"        69","ec_funded":1,"project":[{"grant_number":"101020093","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}],"page":"66-75","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"ToHe"}],"title":"Certificates in AI: Learn but verify","article_type":"original","PlanS_conform":"1","oa_version":"Published Version","type":"journal_article","OA_place":"publisher","publication_identifier":{"eissn":["1557-7317"],"issn":["0001-0782"]},"acknowledgement":"T.A.H. thanks Đorde Žikelic for many stimulating discussions about CML. This work was supported in part by NSFCPS Frontier Grant 1545126, by a BAIR Commons project, by the Berkeley iCy-Phy Center, by the Stanford Center for Automated Reasoning, and by the ERC Advanced Grant 101020093.","file_date_updated":"2026-01-21T08:52:07Z","date_published":"2026-01-01T00:00:00Z","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Association for Computing Machinery","has_accepted_license":"1","corr_author":"1","abstract":[{"lang":"eng","text":"In certifiable machine learning, AI systems produce not only results but also verifiable certificates that the results can be trusted."}],"citation":{"short":"C. Barrett, T.A. Henzinger, S.A. Seshia, Communications of the ACM 69 (2026) 66–75.","chicago":"Barrett, Clark, Thomas A Henzinger, and Sanjit A. Seshia. “Certificates in AI: Learn but Verify.” <i>Communications of the ACM</i>. Association for Computing Machinery, 2026. <a href=\"https://doi.org/10.1145/3737447\">https://doi.org/10.1145/3737447</a>.","apa":"Barrett, C., Henzinger, T. A., &#38; Seshia, S. A. (2026). Certificates in AI: Learn but verify. <i>Communications of the ACM</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3737447\">https://doi.org/10.1145/3737447</a>","ieee":"C. Barrett, T. A. Henzinger, and S. A. Seshia, “Certificates in AI: Learn but verify,” <i>Communications of the ACM</i>, vol. 69, no. 1. Association for Computing Machinery, pp. 66–75, 2026.","ista":"Barrett C, Henzinger TA, Seshia SA. 2026. Certificates in AI: Learn but verify. Communications of the ACM. 69(1), 66–75.","ama":"Barrett C, Henzinger TA, Seshia SA. Certificates in AI: Learn but verify. <i>Communications of the ACM</i>. 2026;69(1):66-75. doi:<a href=\"https://doi.org/10.1145/3737447\">10.1145/3737447</a>","mla":"Barrett, Clark, et al. “Certificates in AI: Learn but Verify.” <i>Communications of the ACM</i>, vol. 69, no. 1, Association for Computing Machinery, 2026, pp. 66–75, doi:<a href=\"https://doi.org/10.1145/3737447\">10.1145/3737447</a>."},"publication":"Communications of the ACM","oa":1,"author":[{"full_name":"Barrett, Clark","last_name":"Barrett","first_name":"Clark"},{"full_name":"Henzinger, Thomas A","first_name":"Thomas A","last_name":"Henzinger","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Seshia, Sanjit A.","first_name":"Sanjit A.","last_name":"Seshia"}],"quality_controlled":"1","month":"01","volume":69,"year":"2026","day":"01","date_created":"2026-01-20T10:08:21Z"},{"publication":"Journal of Advances in Modeling Earth Systems","corr_author":"1","abstract":[{"text":"We have addressed convective self‐aggregation (CSA) in steady and oscillating sea surface temperature (SST) and solar radiation (SOLIN) cloud‐resolving model simulations in a non‐rotating radiative‐convective equilibrium (RCE) framework. Our experiment designs are motivated by land‐ocean heterogeneity of atmospheric convection. The steady and oscillating forcings are idealizations of ocean and land conditions, respectively, based on their differences in heat capacities. In both kinds of simulations, the diurnal mean SST and SOLIN are the same, and both SST and SOLIN are only varied in time (i.e., they are spatially homogeneous at any given time). We find that diurnally oscillating forcing accelerates CSA. Stronger long‐wave cooling in dry regions at night and during the warm SST phase (late afternoon) both allow the long‐wave feedback, known to favor aggregation, to intensify compared to steady forcing simulations. In addition to the long‐wave, reduced short‐wave warming in dry regions (during the day) further enhances radiative cooling there compared to moist regions. Overall, the radiative cooling is enhanced in dry regions compared to neighboring moist convective regions. A dry subsidence is driven by this net radiative (short‐wave plus long‐wave) cooling, consistent with earlier work on CSA. Stronger radiative cooling allows stronger subsidence which allows low‐level circulation to more efficiently transport moisture and energy up‐gradient, driving convection to aggregate faster. We also note a sensitivity of our experimental setup to initial conditions, more so at warmer SST. This stochastic behavior might be critical in reconciling the differences of opinion regarding the response of convection aggregation to oscillating SST forcing.","lang":"eng"}],"citation":{"ista":"GOSWAMI BB, Lu Z, Muller CJ. 2026. Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. Journal of Advances in Modeling Earth Systems. 18(1), e2024MS004576.","ama":"GOSWAMI BB, Lu Z, Muller CJ. Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. <i>Journal of Advances in Modeling Earth Systems</i>. 2026;18(1). doi:<a href=\"https://doi.org/10.1029/2024ms004576\">10.1029/2024ms004576</a>","mla":"GOSWAMI, BIDYUT B., et al. “Convective Self‐aggregation in Diurnally Oscillating Sea Surface Temperature and Solar Forcing Experiments.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 1, e2024MS004576, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2024ms004576\">10.1029/2024ms004576</a>.","short":"B.B. GOSWAMI, Z. Lu, C.J. Muller, Journal of Advances in Modeling Earth Systems 18 (2026).","chicago":"GOSWAMI, BIDYUT B, Ziyin Lu, and Caroline J Muller. “Convective Self‐aggregation in Diurnally Oscillating Sea Surface Temperature and Solar Forcing Experiments.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2024ms004576\">https://doi.org/10.1029/2024ms004576</a>.","apa":"GOSWAMI, B. B., Lu, Z., &#38; Muller, C. J. (2026). Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2024ms004576\">https://doi.org/10.1029/2024ms004576</a>","ieee":"B. B. GOSWAMI, Z. Lu, and C. J. Muller, “Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 1. Wiley, 2026."},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"publisher":"Wiley","has_accepted_license":"1","OA_place":"publisher","publication_identifier":{"eissn":["1942-2466"]},"file_date_updated":"2026-01-21T08:39:01Z","date_published":"2026-01-12T00:00:00Z","acknowledgement":"The authors gratefully acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp). We are grateful to three anonymous reviewer(s) for their insightful suggestions that have improved the quality of our manuscript. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","year":"2026","day":"12","article_number":"e2024MS004576","date_created":"2026-01-20T10:08:54Z","acknowledged_ssus":[{"_id":"ScienComp"}],"volume":18,"author":[{"id":"3a4ac09c-6d61-11ec-bf66-884cde66b64b","orcid":"0000-0001-8602-3083","first_name":"BIDYUT B","last_name":"GOSWAMI","full_name":"GOSWAMI, BIDYUT B"},{"full_name":"Lu, Ziyin","first_name":"Ziyin","last_name":"Lu","id":"a6e549c6-8972-11ed-ae7b-a336d97ac043","orcid":"0009-0008-5320-7730"},{"id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","orcid":"0000-0001-5836-5350","first_name":"Caroline J","last_name":"Muller","full_name":"Muller, Caroline J"}],"quality_controlled":"1","month":"01","oa":1,"doi":"10.1029/2024ms004576","scopus_import":"1","intvolume":"        18","date_updated":"2026-01-21T08:41:19Z","issue":"1","publication_status":"published","status":"public","file":[{"relation":"main_file","file_size":19509786,"file_id":"21027","creator":"dernst","success":1,"content_type":"application/pdf","date_created":"2026-01-21T08:39:01Z","access_level":"open_access","date_updated":"2026-01-21T08:39:01Z","file_name":"2026_JAMES_Goswami.pdf","checksum":"6ea369e3b46bea58efab4f38b6c671a7"}],"_id":"21013","ddc":["550"],"OA_type":"gold","article_processing_charge":"Yes","language":[{"iso":"eng"}],"article_type":"original","oa_version":"Published Version","PlanS_conform":"1","type":"journal_article","department":[{"_id":"CaMu"},{"_id":"BjHo"},{"_id":"GradSch"}],"title":"Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ec_funded":1,"DOAJ_listed":"1","project":[{"_id":"629205d8-2b32-11ec-9570-e1356ff73576","call_identifier":"H2020","grant_number":"805041","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate"}]},{"volume":22,"day":"05","year":"2026","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"date_created":"2026-01-20T10:12:19Z","oa":1,"quality_controlled":"1","related_material":{"link":[{"description":"News on ISTA website","relation":"research_data","url":"https://ista.ac.at/en/news/geometry-shapes-life/"}]},"author":[{"orcid":"0000-0002-6425-5788","id":"C4D70E82-1081-11EA-B3ED-9A4C3DDC885E","first_name":"Nikhil","last_name":"Mishra","full_name":"Mishra, Nikhil"},{"full_name":"Li, Yuting I","last_name":"Li","first_name":"Yuting I","id":"ee7a5ca8-8b71-11ed-b662-b3341c05b7eb"},{"full_name":"Hannezo, Edouard B","last_name":"Hannezo","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561"},{"first_name":"Carl-Philipp J","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J"}],"month":"01","abstract":[{"lang":"eng","text":"Early embryo geometry is one of the most invariant species-specific traits, yet its role in ensuring developmental reproducibility and robustness remains underexplored. Here we show that in zebrafish, the geometry of the fertilized egg—specifically its curvature and volume—serves as a critical initial condition triggering a cascade of events that influence development. The embryo geometry guides patterned asymmetric cell divisions in the blastoderm, generating radial gradients of cell volume and nucleocytoplasmic ratio. These gradients generate mitotic phase waves, with the nucleocytoplasmic ratio determining individual cell cycle periods independently of other cells. We demonstrate that reducing cell autonomy reshapes these waves, emphasizing the instructive role of geometry-derived volume patterns in setting the intrinsic period of the cell cycle oscillator. In addition to organizing cell cycles, early embryo geometry spatially patterns zygotic genome activation at the midblastula transition, a key step in establishing embryonic autonomy. Disrupting the embryo shape alters the zygotic genome activation pattern and causes ectopic germ layer specification, underscoring the developmental significance of geometry. Together, our findings reveal a symmetry-breaking function of early embryo geometry in coordinating cell cycle and transcriptional patterning."}],"corr_author":"1","citation":{"ieee":"N. Mishra, Y. I. Li, E. B. Hannezo, and C.-P. J. Heisenberg, “Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 139–150, 2026.","apa":"Mishra, N., Li, Y. I., Hannezo, E. B., &#38; Heisenberg, C.-P. J. (2026). Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03122-1\">https://doi.org/10.1038/s41567-025-03122-1</a>","chicago":"Mishra, Nikhil, Yuting I Li, Edouard B Hannezo, and Carl-Philipp J Heisenberg. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03122-1\">https://doi.org/10.1038/s41567-025-03122-1</a>.","short":"N. Mishra, Y.I. Li, E.B. Hannezo, C.-P.J. Heisenberg, Nature Physics 22 (2026) 139–150.","mla":"Mishra, Nikhil, et al. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” <i>Nature Physics</i>, vol. 22, Springer Nature, 2026, pp. 139–50, doi:<a href=\"https://doi.org/10.1038/s41567-025-03122-1\">10.1038/s41567-025-03122-1</a>.","ama":"Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. <i>Nature Physics</i>. 2026;22:139-150. doi:<a href=\"https://doi.org/10.1038/s41567-025-03122-1\">10.1038/s41567-025-03122-1</a>","ista":"Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. 2026. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. Nature Physics. 22, 139–150."},"publication":"Nature Physics","file_date_updated":"2026-01-21T08:21:11Z","acknowledgement":"We thank N. Petridou (EMBL) for sharing results before publication. N.M. was supported by funding from the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie COFUND Actions ISTplus grant agreement number 754411. Y.I.L. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. The research was supported by funding to C.-P.H. from the NOMIS Foundation, Project ID 1.844. We would like to thank past and present members of the Heisenberg and Hannezo groups for discussions, particularly S. Shamipour, V. Doddihal, M. Jovic, N. Hino, F. N. Arslan, R. Kobylinska and C. Camelo for feedback on the draft manuscript. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria through resources provided by the Aquatics Facility, Imaging & Optics Facility (IOF), Scientific Computing (SciComp) facility and Lab Support Facility (LSF). Open access funding provided by Institute of Science and Technology (IST Austria).","external_id":{"oaworkid":["W7118187193"]},"date_published":"2026-01-05T00:00:00Z","OA_place":"publisher","publication_identifier":{"issn":["1745-2473"],"issnl":[" 1745-2473"],"eissn":["1745-2481"]},"publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"has_accepted_license":"1","department":[{"_id":"EdHa"},{"_id":"CaHe"}],"title":"Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo","article_type":"original","type":"journal_article","oaworkid":1,"oa_version":"Published Version","PlanS_conform":"1","ec_funded":1,"project":[{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413"},{"_id":"917c023a-16d5-11f0-9cad-eb5cafc52090","name":"Cytoplasmic self-organization into cell-like compartments as a common guiding principle in early animal development"}],"page":"139-150","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_updated":"2026-04-28T12:55:30Z","status":"public","publication_status":"published","scopus_import":"1","doi":"10.1038/s41567-025-03122-1","intvolume":"        22","ddc":["570"],"_id":"21015","file":[{"file_id":"21026","creator":"dernst","relation":"main_file","file_size":7335694,"file_name":"2026_NaturePhysics_Mishra.pdf","checksum":"0ab7ac2fbcb61a364dba57152db64ed7","access_level":"open_access","date_updated":"2026-01-21T08:21:11Z","content_type":"application/pdf","date_created":"2026-01-21T08:21:11Z","success":1}],"article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"OA_type":"hybrid"},{"publication":"La Matematica","citation":{"chicago":"Brigati, Giovanni, Jean Dolbeault, and Nikita Simonov. “Logarithmic Sobolev Inequalities: A Review on Stability and Instability Results.” <i>La Matematica</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s44007-025-00180-y\">https://doi.org/10.1007/s44007-025-00180-y</a>.","short":"G. Brigati, J. Dolbeault, N. Simonov, La Matematica 5 (2026).","apa":"Brigati, G., Dolbeault, J., &#38; Simonov, N. (2026). Logarithmic Sobolev Inequalities: A review on stability and instability results. <i>La Matematica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s44007-025-00180-y\">https://doi.org/10.1007/s44007-025-00180-y</a>","ieee":"G. Brigati, J. Dolbeault, and N. Simonov, “Logarithmic Sobolev Inequalities: A review on stability and instability results,” <i>La Matematica</i>, vol. 5. Springer Nature, 2026.","ista":"Brigati G, Dolbeault J, Simonov N. 2026. Logarithmic Sobolev Inequalities: A review on stability and instability results. La Matematica. 5, 5.","ama":"Brigati G, Dolbeault J, Simonov N. Logarithmic Sobolev Inequalities: A review on stability and instability results. <i>La Matematica</i>. 2026;5. doi:<a href=\"https://doi.org/10.1007/s44007-025-00180-y\">10.1007/s44007-025-00180-y</a>","mla":"Brigati, Giovanni, et al. “Logarithmic Sobolev Inequalities: A Review on Stability and Instability Results.” <i>La Matematica</i>, vol. 5, 5, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s44007-025-00180-y\">10.1007/s44007-025-00180-y</a>."},"abstract":[{"lang":"eng","text":"In this paper, we review recent results on stability and instability in logarithmic Sobolev inequalities, with a particular emphasis on strong norms. We consider several versions of these inequalities on the Euclidean space, for the Lebesgue and the Gaussian measures, and discuss their differences in terms of moments and stability. We give new and direct proofs, as well as examples and discuss the stability of a logarithmic uncertainty principle. Although we do not cover all aspects of the topic, we hope to contribute to establishing the state of the art."}],"corr_author":"1","has_accepted_license":"1","publisher":"Springer Nature","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_published":"2026-01-08T00:00:00Z","file_date_updated":"2026-01-21T07:45:03Z","external_id":{"arxiv":["2504.08658"]},"acknowledgement":"This work has been supported by the Project Conviviality (ANR-23-CE40–0003) of the French National Research Agency. G.B. has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. The authors thank a referee for a careful reading and suggestions which result in a significant improvement of the manuscript. Open access funding provided by Institute of Science and Technology (IST Austria). The work of GB has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. This work has been supported by the Project Conviviality (ANR-23-CE40–0003) of the French National Research Agency.","OA_place":"publisher","publication_identifier":{"issn":["2730-9657"]},"date_created":"2026-01-20T10:14:55Z","day":"08","article_number":"5","year":"2026","volume":5,"month":"01","quality_controlled":"1","author":[{"full_name":"Brigati, Giovanni","first_name":"Giovanni","last_name":"Brigati","id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1"},{"first_name":"Jean","last_name":"Dolbeault","full_name":"Dolbeault, Jean"},{"full_name":"Simonov, Nikita","first_name":"Nikita","last_name":"Simonov"}],"oa":1,"intvolume":"         5","scopus_import":"1","doi":"10.1007/s44007-025-00180-y","status":"public","publication_status":"published","date_updated":"2026-01-21T07:48:28Z","article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"OA_type":"hybrid","ddc":["510"],"file":[{"date_updated":"2026-01-21T07:45:03Z","access_level":"open_access","checksum":"0702d8397f216555b1d5286e5d77f09c","file_name":"2026_LaMatematica_Brigati.pdf","success":1,"date_created":"2026-01-21T07:45:03Z","content_type":"application/pdf","file_id":"21025","creator":"dernst","relation":"main_file","file_size":4992025}],"_id":"21018","type":"journal_article","PlanS_conform":"1","oa_version":"Published Version","article_type":"original","title":"Logarithmic Sobolev Inequalities: A review on stability and instability results","department":[{"_id":"JaMa"}],"arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"ec_funded":1},{"article_type":"original","oa_version":"Published Version","type":"journal_article","department":[{"_id":"CaMu"}],"title":"No decrease of tropical convection in individual deep convective systems with global warming","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","DOAJ_listed":"1","ec_funded":1,"project":[{"call_identifier":"H2020","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","grant_number":"805041","_id":"629205d8-2b32-11ec-9570-e1356ff73576"}],"scopus_import":"1","doi":"10.1038/s41612-025-01285-5","intvolume":"         9","date_updated":"2026-02-12T08:41:09Z","publication_status":"published","status":"public","_id":"21035","file":[{"file_id":"21215","creator":"dernst","file_size":511226,"relation":"main_file","date_updated":"2026-02-12T08:39:27Z","access_level":"open_access","checksum":"c433bba3822b3c6c4a5260ad5e2429a0","file_name":"2026_njpClimateAtmScience_Bolot.pdf","success":1,"date_created":"2026-02-12T08:39:27Z","content_type":"application/pdf"}],"ddc":["550"],"OA_type":"gold","language":[{"iso":"eng"}],"article_processing_charge":"Yes","year":"2026","day":"15","article_number":"14","date_created":"2026-01-25T23:01:38Z","volume":9,"author":[{"last_name":"Bolot","first_name":"Maximilien","full_name":"Bolot, Maximilien"},{"full_name":"Roca, Rémy","first_name":"Rémy","last_name":"Roca"},{"last_name":"Fiolleau","first_name":"Thomas","full_name":"Fiolleau, Thomas"},{"full_name":"Muller, Caroline J","orcid":"0000-0001-5836-5350","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","last_name":"Muller","first_name":"Caroline J"}],"quality_controlled":"1","month":"01","oa":1,"publication":"npj Climate and Atmospheric Science","abstract":[{"lang":"eng","text":"According to the scientific consensus, tropical convection must decrease with global warming. This decrease is manifested by a decrease of the mass transported in the upward branch of the atmospheric overturning circulation – the convective mass flux – and a connected decrease of high clouds in the tropics, with implications for climate sensitivity. By using kilometer-scale simulations in radiative-convective equilibrium and a convective tracking algorithm, we show that no such decrease occurs in storms when taken individually and that the mass transport per storm increases instead. Storms can achieve this result by aggregating more surface of the convective cores – the inner part of the storm doing the vertical transport – so that the decrease of tropical convection is actually explained by a decrease in the total number of storms. There is little variation of the mean pressure velocity in the cores of the storms, a robust finding of this study. This remarkable invariance of the mean pressure velocity points to an emerging property of convection that should receive more attention in future studies."}],"citation":{"mla":"Bolot, Maximilien, et al. “No Decrease of Tropical Convection in Individual Deep Convective Systems with Global Warming.” <i>Npj Climate and Atmospheric Science</i>, vol. 9, 14, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41612-025-01285-5\">10.1038/s41612-025-01285-5</a>.","ama":"Bolot M, Roca R, Fiolleau T, Muller CJ. No decrease of tropical convection in individual deep convective systems with global warming. <i>npj Climate and Atmospheric Science</i>. 2026;9. doi:<a href=\"https://doi.org/10.1038/s41612-025-01285-5\">10.1038/s41612-025-01285-5</a>","ista":"Bolot M, Roca R, Fiolleau T, Muller CJ. 2026. No decrease of tropical convection in individual deep convective systems with global warming. npj Climate and Atmospheric Science. 9, 14.","ieee":"M. Bolot, R. Roca, T. Fiolleau, and C. J. Muller, “No decrease of tropical convection in individual deep convective systems with global warming,” <i>npj Climate and Atmospheric Science</i>, vol. 9. Springer Nature, 2026.","apa":"Bolot, M., Roca, R., Fiolleau, T., &#38; Muller, C. J. (2026). No decrease of tropical convection in individual deep convective systems with global warming. <i>Npj Climate and Atmospheric Science</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41612-025-01285-5\">https://doi.org/10.1038/s41612-025-01285-5</a>","chicago":"Bolot, Maximilien, Rémy Roca, Thomas Fiolleau, and Caroline J Muller. “No Decrease of Tropical Convection in Individual Deep Convective Systems with Global Warming.” <i>Npj Climate and Atmospheric Science</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41612-025-01285-5\">https://doi.org/10.1038/s41612-025-01285-5</a>.","short":"M. Bolot, R. Roca, T. Fiolleau, C.J. Muller, Npj Climate and Atmospheric Science 9 (2026)."},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"publisher":"Springer Nature","has_accepted_license":"1","pmid":1,"OA_place":"publisher","publication_identifier":{"eissn":["2397-3722"]},"date_published":"2026-01-15T00:00:00Z","acknowledgement":"We thank Sophie Cloché for her support with the handling of the various datasets. This study benefited from the IPSL mesocenter ESPRI facility which is supported by CNRS, UPMC, Labex L-IPSL, CNES and Ecole Polytechnique. The authors acknowledge the CNES and CNRS support under the Megha-Tropiques program. C.M. gratefully acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041).","file_date_updated":"2026-02-12T08:39:27Z","external_id":{"pmid":["41550270"]}},{"month":"01","author":[{"full_name":"Shi, Changwei","last_name":"Shi","first_name":"Changwei"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","first_name":"Sharona","full_name":"Horta, Sharona"},{"full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","last_name":"Ibáñez","first_name":"Maria"},{"full_name":"Kallio, Tanja","last_name":"Kallio","first_name":"Tanja"},{"full_name":"Martínez-Alanis, Paulina R.","last_name":"Martínez-Alanis","first_name":"Paulina R."},{"full_name":"Wang, Xiang","first_name":"Xiang","last_name":"Wang"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"}],"quality_controlled":"1","oa":1,"date_created":"2026-01-25T23:01:39Z","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"year":"2026","article_number":"123348","day":"12","volume":324,"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Elsevier","OA_place":"publisher","publication_identifier":{"issn":["1873-4405"],"eissn":["0009-2509"]},"acknowledgement":"The authors thank the support from the National Natural Science Foundation of China (NSFC) (Grants No. 22302151) and Natural Science Foundation of Hubei Province (Grants No. 2024AFB755, 2024AFB267), Key Project of Hubei Provincial Department of Education Scientific Research Plan (F2023007). This work is supported by funding from Shandong Provincial Key Laboratory of MonocrystallineSilicon Semiconductor Materials and Technology (2025KFKT021). This research was supported by the Scientific Service Units (SSU) of ISTA Austria through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NNF). “M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation.”","date_published":"2026-01-12T00:00:00Z","publication":"Chemical Engineering Science","main_file_link":[{"url":"https://doi.org/10.1016/j.ces.2026.123348","open_access":"1"}],"citation":{"apa":"Shi, C., Horta, S., Ibáñez, M., Kallio, T., Martínez-Alanis, P. R., Wang, X., &#38; Cabot, A. (2026). Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. <i>Chemical Engineering Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ces.2026.123348\">https://doi.org/10.1016/j.ces.2026.123348</a>","chicago":"Shi, Changwei, Sharona Horta, Maria Ibáñez, Tanja Kallio, Paulina R. Martínez-Alanis, Xiang Wang, and Andreu Cabot. “Hydrogen Induced Palladium-Based Heterojunction Electrocatalysts to Enhance the Oxygen Reduction Reaction Performance.” <i>Chemical Engineering Science</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ces.2026.123348\">https://doi.org/10.1016/j.ces.2026.123348</a>.","short":"C. Shi, S. Horta, M. Ibáñez, T. Kallio, P.R. Martínez-Alanis, X. Wang, A. Cabot, Chemical Engineering Science 324 (2026).","ieee":"C. Shi <i>et al.</i>, “Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance,” <i>Chemical Engineering Science</i>, vol. 324. Elsevier, 2026.","ista":"Shi C, Horta S, Ibáñez M, Kallio T, Martínez-Alanis PR, Wang X, Cabot A. 2026. Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. Chemical Engineering Science. 324, 123348.","mla":"Shi, Changwei, et al. “Hydrogen Induced Palladium-Based Heterojunction Electrocatalysts to Enhance the Oxygen Reduction Reaction Performance.” <i>Chemical Engineering Science</i>, vol. 324, 123348, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ces.2026.123348\">10.1016/j.ces.2026.123348</a>.","ama":"Shi C, Horta S, Ibáñez M, et al. Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance. <i>Chemical Engineering Science</i>. 2026;324. doi:<a href=\"https://doi.org/10.1016/j.ces.2026.123348\">10.1016/j.ces.2026.123348</a>"},"abstract":[{"text":"The oxygen reduction reaction (ORR) remains a critical bottleneck in fuel cells and metal-air batteries due to the lack of highly efficient electrocatalysts. Here, we report a simple strategy for synthesizing a palladium-based heterostructured electrocatalyst supported on a carbon nitride matrix (PdH-Pd@CN), which exhibits remarkable ORR activity with a half-wave potential of 0.91 V and excellent durability in 0.1 M KOH. Within the heterostructure, hydrogen intercalation expands the Pd lattice, while interstitial hydrogen doping facilitates charge transfer from Pd to H owing to their electronegativity difference. These synergistic effects modulate the electronic structure, thereby enhancing both activity and stability. When employed in Zn-air batteries, PdH-Pd@CN delivers a maximum power density of 176 mW cm− (Liu et al., 2025) and capacity of 805 mAh g− (Sun et al., 2021) Zn. These findings demonstrate the strong potential of PdH-Pd@CN as an efficient ORR electrocatalyst for next-generation metal-air batteries and related energy technologies.","lang":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"oa_version":"Published Version","PlanS_conform":"1","type":"journal_article","article_type":"original","title":"Hydrogen induced palladium-based heterojunction electrocatalysts to enhance the oxygen reduction reaction performance","department":[{"_id":"MaIb"}],"OA_type":"hybrid","article_processing_charge":"Yes (in subscription journal)","language":[{"iso":"eng"}],"_id":"21037","ddc":["540"],"intvolume":"       324","doi":"10.1016/j.ces.2026.123348","scopus_import":"1","publication_status":"epub_ahead","status":"public","date_updated":"2026-02-12T13:05:19Z"},{"volume":545,"date_created":"2026-01-25T23:01:39Z","year":"2026","day":"01","article_number":"staf2131","oa":1,"month":"02","author":[{"last_name":"Chang","first_name":"Seok Jun","full_name":"Chang, Seok Jun"},{"full_name":"Gronke, Max","last_name":"Gronke","first_name":"Max"},{"full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee"},{"last_name":"Mason","first_name":"Charlotte","full_name":"Mason, Charlotte"}],"quality_controlled":"1","citation":{"mla":"Chang, Seok Jun, et al. “Impact of Resonance, Raman, and Thomson Scattering on Hydrogen Line Formation in Little Red Dots.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 545, no. 4, staf2131, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/mnras/staf2131\">10.1093/mnras/staf2131</a>.","ama":"Chang SJ, Gronke M, Matthee JJ, Mason C. Impact of resonance, Raman, and Thomson scattering on hydrogen line formation in Little Red Dots. <i>Monthly Notices of the Royal Astronomical Society</i>. 2026;545(4). doi:<a href=\"https://doi.org/10.1093/mnras/staf2131\">10.1093/mnras/staf2131</a>","ista":"Chang SJ, Gronke M, Matthee JJ, Mason C. 2026. Impact of resonance, Raman, and Thomson scattering on hydrogen line formation in Little Red Dots. Monthly Notices of the Royal Astronomical Society. 545(4), staf2131.","ieee":"S. J. Chang, M. Gronke, J. J. Matthee, and C. Mason, “Impact of resonance, Raman, and Thomson scattering on hydrogen line formation in Little Red Dots,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 545, no. 4. Oxford University Press, 2026.","apa":"Chang, S. J., Gronke, M., Matthee, J. J., &#38; Mason, C. (2026). Impact of resonance, Raman, and Thomson scattering on hydrogen line formation in Little Red Dots. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/staf2131\">https://doi.org/10.1093/mnras/staf2131</a>","short":"S.J. Chang, M. Gronke, J.J. Matthee, C. Mason, Monthly Notices of the Royal Astronomical Society 545 (2026).","chicago":"Chang, Seok Jun, Max Gronke, Jorryt J Matthee, and Charlotte Mason. “Impact of Resonance, Raman, and Thomson Scattering on Hydrogen Line Formation in Little Red Dots.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/mnras/staf2131\">https://doi.org/10.1093/mnras/staf2131</a>."},"abstract":[{"text":"Little Red Dots (LRDs) are compact sources at z > 5 discovered through James Webb Space Telescope spectroscopy. Their spectra exhibit broad Balmer emission lines (>~1000 km s^−1), alongside absorption features and a pronounced Balmer break – evidence for a dense, neutral hydrogen medium, in which the n = 2 state is significantly populated. When interpreted as arising\r\nfrom active galactic nucleus broad-line regions, inferred black hole masses from local scaling relations exceed expectations given their stellar masses, challenging models of early black hole–galaxy co-evolution. However, radiative transfer effects in dense media may also impact the formation of hydrogen emission lines. We model three scattering processes shaping hydrogen\r\nline profiles: resonance scattering by hydrogen in the n = 2 state, Raman scattering of ultraviolet (UV) radiation by ground-state hydrogen, and Thomson scattering by free electrons. Using 3D Monte Carlo radiative transfer simulations, we examine their imprint on line shapes and ratios. Resonance scattering produces strong deviations from Case B flux ratios, clear differences\r\nbetween Hα and Hβ, and encodes gas kinematics in line profiles but cannot broaden Hβ due to conversion to Paα. While Raman scattering can yield broad wings, scattering of the UV continuum is disfavoured given the absence of strong full width at half-maximum variations across transitions. Raman scattering of higher Lyman-series emission can produce Hα/Hβ wing\r\nwidth ratios of  >~1.28, agreeing with observations. Thomson scattering can reproduce the observed >~ 1000 km s^−1 wings under plausible conditions – e.g. Te ∼ 10^4 K and Ne ∼ 10^24 cm^−2 – and lead to black hole mass overestimates by factors  10. Our results provide a framework for interpreting hydrogen lines in LRDs and similar systems.","lang":"eng"}],"publication":"Monthly Notices of the Royal Astronomical Society","OA_place":"publisher","publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"acknowledgement":"The authorsthank the anonymousreferee for constructive comments, which improved the clarity of this paper. SJC acknowledges support from the ERC synergy grant 101166930 – RECAP. MG thanks the Max Planck Society for support through the Max Planck Research Group, and the European Union forsupport through ERC-2024-STG 101165038 (ReMMU). JM acknowledges funding by the European Union (ERC, AGENTS, 101076224). CAM acknowledges support\r\nby the European Union ERC grant RISES (101163035), Carlsberg Foundation (CF22-1322), and VILLUM FONDEN (37459). Computations were performed on HPC systems Freya and Orion at the Max Planck Computing and Data Facility.","file_date_updated":"2026-02-12T12:44:33Z","date_published":"2026-02-01T00:00:00Z","external_id":{"arxiv":["2508.08768"]},"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Oxford University Press","title":"Impact of resonance, Raman, and Thomson scattering on hydrogen line formation in Little Red Dots","department":[{"_id":"JoMa"}],"oa_version":"Published Version","PlanS_conform":"1","type":"journal_article","article_type":"original","project":[{"grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization","_id":"bd9b2118-d553-11ed-ba76-db24564edfea"}],"DOAJ_listed":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1,"issue":"4","publication_status":"published","status":"public","date_updated":"2026-02-12T12:56:33Z","intvolume":"       545","scopus_import":"1","doi":"10.1093/mnras/staf2131","article_processing_charge":"Yes","language":[{"iso":"eng"}],"OA_type":"gold","file":[{"access_level":"open_access","date_updated":"2026-02-12T12:44:33Z","file_name":"2026_MonthNoticesRAS_Chang.pdf","checksum":"52ba7d7b5b80af0c50f57e4c2acc3930","success":1,"content_type":"application/pdf","date_created":"2026-02-12T12:44:33Z","file_id":"21220","creator":"dernst","relation":"main_file","file_size":5600366}],"_id":"21038","ddc":["520"]},{"date_created":"2026-01-25T23:01:39Z","day":"15","article_number":"dev205225","year":"2026","volume":153,"month":"01","quality_controlled":"1","author":[{"full_name":"Qian, Qingyin","first_name":"Qingyin","last_name":"Qian"},{"full_name":"Nagai, Hiroki","last_name":"Nagai","first_name":"Hiroki","id":"608df3e6-e2ab-11ed-8890-c9318cec7da4","orcid":"0000-0003-1671-9434"},{"first_name":"Yuya","last_name":"Sanaki","full_name":"Sanaki, Yuya"},{"first_name":"Makoto","last_name":"Hayashi","full_name":"Hayashi, Makoto"},{"first_name":"Kenichi","last_name":"Kimura","full_name":"Kimura, Kenichi"},{"first_name":"Yu Ichiro","last_name":"Nakajima","full_name":"Nakajima, Yu Ichiro"},{"last_name":"Niwa","first_name":"Ryusuke","full_name":"Niwa, Ryusuke"}],"oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.07.05.662934"}],"publication":"Development","citation":{"apa":"Qian, Q., NAGAI, H., Sanaki, Y., Hayashi, M., Kimura, K., Nakajima, Y. I., &#38; Niwa, R. (2026). Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. <i>Development</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/dev.205225\">https://doi.org/10.1242/dev.205225</a>","chicago":"Qian, Qingyin, HIROKI NAGAI, Yuya Sanaki, Makoto Hayashi, Kenichi Kimura, Yu Ichiro Nakajima, and Ryusuke Niwa. “Xrp1 Drives Damage-Induced Cellular Plasticity of Enteroendocrine Cells in the Adult Drosophila Midgut.” <i>Development</i>. The Company of Biologists, 2026. <a href=\"https://doi.org/10.1242/dev.205225\">https://doi.org/10.1242/dev.205225</a>.","short":"Q. Qian, H. NAGAI, Y. Sanaki, M. Hayashi, K. Kimura, Y.I. Nakajima, R. Niwa, Development 153 (2026).","ieee":"Q. Qian <i>et al.</i>, “Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut,” <i>Development</i>, vol. 153, no. 2. The Company of Biologists, 2026.","ista":"Qian Q, NAGAI H, Sanaki Y, Hayashi M, Kimura K, Nakajima YI, Niwa R. 2026. Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. Development. 153(2), dev205225.","mla":"Qian, Qingyin, et al. “Xrp1 Drives Damage-Induced Cellular Plasticity of Enteroendocrine Cells in the Adult Drosophila Midgut.” <i>Development</i>, vol. 153, no. 2, dev205225, The Company of Biologists, 2026, doi:<a href=\"https://doi.org/10.1242/dev.205225\">10.1242/dev.205225</a>.","ama":"Qian Q, NAGAI H, Sanaki Y, et al. Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut. <i>Development</i>. 2026;153(2). doi:<a href=\"https://doi.org/10.1242/dev.205225\">10.1242/dev.205225</a>"},"abstract":[{"text":"Cellular plasticity, the ability of a differentiated cell to adopt another phenotypic identity, is restricted under basal conditions, but can be elicited upon damage. However, the molecular mechanism enabling such plasticity remains largely unexplored. Here, we report damage-induced cellular plasticity of secretory enteroendocrine cells (EEs) in the adult Drosophila midgut. Ionizing radiation induces EE fate conversion and activates stress-responsive programs in EE lineages, accompanied by the induction of the stress-inducible transcription factor Xrp1 and the cytokine gene upd3. Xrp1 and upd3 are both necessary for radiation-induced EE plasticity. Under basal conditions, EE-specific Xrp1 overexpression triggers ectopic expression of progenitor-specific genes, which is necessary for Xrp1 to drive EE plasticity. Our work identifies Xrp1 as a crucial regulator that coordinates damage-induced signaling and transcriptional reprogramming, enabling the reactivation of cellular plasticity in differentiated cells.","lang":"eng"}],"publisher":"The Company of Biologists","date_published":"2026-01-15T00:00:00Z","external_id":{"pmid":["41392708"]},"acknowledgement":"We thank Pierre Léopold, Tatsushi Igaki, Erik Storkebaum, Tobias Reiff, Masayuki Miura, Xiaohang Yang, Mikio Furuse, Bloomington Drosophila Stock Center and Developmental Studies Hybridoma Bank for providing us with fly stocks and reagents. We are also grateful to Hiromi Yanagisawa, Satoru Kobayashi, Md Al Amin Sheikh and Yaxuan Cui for allowing us to use their equipment, and to Allison Bardin, Pierre Léopold and Tadashi Uemura for helpful discussions.","OA_place":"repository","publication_identifier":{"issn":["0950-1991"],"eissn":["1477-9129"]},"pmid":1,"type":"journal_article","oa_version":"Preprint","article_type":"original","title":"Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut","department":[{"_id":"XiFe"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       153","doi":"10.1242/dev.205225","scopus_import":"1","status":"public","issue":"2","publication_status":"published","date_updated":"2026-02-12T12:41:18Z","OA_type":"green","language":[{"iso":"eng"}],"article_processing_charge":"No","_id":"21039"},{"article_type":"original","type":"journal_article","oa_version":"Published Version","PlanS_conform":"1","department":[{"_id":"StFr"}],"title":"Structural rearrangements of a Cobalt-free Lithium-rich layered oxide cathode during formation","page":"686-697","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1021/acsaem.5c03511","scopus_import":"1","intvolume":"         9","date_updated":"2026-02-12T14:04:04Z","status":"public","issue":"1","publication_status":"published","ddc":["540"],"file":[{"relation":"main_file","file_size":5977526,"file_id":"21222","creator":"dernst","content_type":"application/pdf","date_created":"2026-02-12T13:55:28Z","success":1,"file_name":"2026_AppliedEnergyMaterials_Busato.pdf","checksum":"81272c19df41c696c1737168d3ea8c16","access_level":"open_access","date_updated":"2026-02-12T13:55:28Z"}],"_id":"21040","OA_type":"hybrid","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","day":"12","year":"2026","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"LifeSc"}],"date_created":"2026-01-25T23:01:40Z","volume":9,"quality_controlled":"1","author":[{"first_name":"Matteo","last_name":"Busato","full_name":"Busato, Matteo"},{"full_name":"Tuccillo, Mariarosaria","first_name":"Mariarosaria","last_name":"Tuccillo"},{"full_name":"Celeste, Arcangelo","first_name":"Arcangelo","last_name":"Celeste"},{"full_name":"Tofoni, Alessandro","first_name":"Alessandro","last_name":"Tofoni"},{"first_name":"Laura","last_name":"Silvestri","full_name":"Silvestri, Laura"},{"last_name":"D’Angelo","first_name":"Paola","full_name":"D’Angelo, Paola"},{"full_name":"Freunberger, Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","last_name":"Freunberger","first_name":"Stefan Alexander"},{"full_name":"Brutti, Sergio","first_name":"Sergio","last_name":"Brutti"}],"month":"01","oa":1,"publication":"ACS Applied Energy Materials","abstract":[{"text":"Formation during the first cycles of Li-rich layered oxide (LRLO) cathode materials consolidates the interphase and leads to structural changes that are decisive for long-term cyclability. However, the nature and effect of the changes are material-dependent and unknown for the important class of Co-free, Ni-poor LRLOs. Here, we analyze the processes during the tailored formation procedure of a typical class member, Li1.28Ni0.15Mn0.57O2, and demonstrate that it remarkably changes lattice composition and structure as a prerequisite for stable cycling. We combine electrochemistry, operando mass spectrometry, X-ray diffraction, and X-ray absorption spectroscopy with density functional theory simulations. Activation most prominently compresses the layer spacing along the c-axis and increases reversible structural breathing. The large capacity of ∼250 mAh g–1 originates from the Ni2+/Ni4+ and O2–/O– redox couples. Electron exchange during O-redox is smeared over the entire anionic sublattice rather than localized on specific oxygen atomic sites. This redox mechanism is reversible without detrimental oxygen evolution, avoiding continued degradation common in conventional LRLOs. Sequential Ni- and O-redox during activation irreversibly distorts the coordination of the redox-inactive Mn4+ centers. This structural evolution of the MnO6 octahedra appears to enable the superior electrochemical performance of this LRLO phase. These findings define an activation pathway for the important class of Co-free, Ni-poor LRLOs, offering potential guidance for the rational design of high-performance, more sustainable cathode materials.","lang":"eng"}],"corr_author":"1","citation":{"ieee":"M. Busato <i>et al.</i>, “Structural rearrangements of a Cobalt-free Lithium-rich layered oxide cathode during formation,” <i>ACS Applied Energy Materials</i>, vol. 9, no. 1. American Chemical Society, pp. 686–697, 2026.","chicago":"Busato, Matteo, Mariarosaria Tuccillo, Arcangelo Celeste, Alessandro Tofoni, Laura Silvestri, Paola D’Angelo, Stefan Alexander Freunberger, and Sergio Brutti. “Structural Rearrangements of a Cobalt-Free Lithium-Rich Layered Oxide Cathode during Formation.” <i>ACS Applied Energy Materials</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsaem.5c03511\">https://doi.org/10.1021/acsaem.5c03511</a>.","short":"M. Busato, M. Tuccillo, A. Celeste, A. Tofoni, L. Silvestri, P. D’Angelo, S.A. Freunberger, S. Brutti, ACS Applied Energy Materials 9 (2026) 686–697.","apa":"Busato, M., Tuccillo, M., Celeste, A., Tofoni, A., Silvestri, L., D’Angelo, P., … Brutti, S. (2026). Structural rearrangements of a Cobalt-free Lithium-rich layered oxide cathode during formation. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaem.5c03511\">https://doi.org/10.1021/acsaem.5c03511</a>","ama":"Busato M, Tuccillo M, Celeste A, et al. Structural rearrangements of a Cobalt-free Lithium-rich layered oxide cathode during formation. <i>ACS Applied Energy Materials</i>. 2026;9(1):686-697. doi:<a href=\"https://doi.org/10.1021/acsaem.5c03511\">10.1021/acsaem.5c03511</a>","mla":"Busato, Matteo, et al. “Structural Rearrangements of a Cobalt-Free Lithium-Rich Layered Oxide Cathode during Formation.” <i>ACS Applied Energy Materials</i>, vol. 9, no. 1, American Chemical Society, 2026, pp. 686–97, doi:<a href=\"https://doi.org/10.1021/acsaem.5c03511\">10.1021/acsaem.5c03511</a>.","ista":"Busato M, Tuccillo M, Celeste A, Tofoni A, Silvestri L, D’Angelo P, Freunberger SA, Brutti S. 2026. Structural rearrangements of a Cobalt-free Lithium-rich layered oxide cathode during formation. ACS Applied Energy Materials. 9(1), 686–697."},"publisher":"American Chemical Society","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"has_accepted_license":"1","file_date_updated":"2026-02-12T13:55:28Z","acknowledgement":"Elettra-Sincrotrone Trieste S.C.p.A. and its staff are acknowledged for providing synchrotron radiation beamtime and laboratory facilities, in particular the MCX and XAFS beamlines, where the XRD and XAS experiments have been carried out, supported by the projects number: 20217082, 20205109, and 20195014. This study was carried out within the MOST─Sustainable Mobility Center and received funding from the European Union Next-Generation EU (PIANO NAZIONALE DI RIPRESA E RESILIENZA (PNRR)─MISSIONE 4 COMPONENTE 2, INVESTIMENTO 1.4─D.D. 1033 17/06/2022, CN00000023). Moreover, the contribution of S.B. and A.C. to this study was carried out within the NEST─Network for Energy Sustainable Transition and received funding from the European Union Next-Generation EU (PNRR─MISSIONE 4 COMPONENTE 2, INVESTIMENTO 1.3─D.D. 1561 11/10/2022, B53C22004070006). This manuscript reflects only the authors’ views and opinions, neither the European Union nor the European Commission can be considered responsible for them. Two of us, S.B. and S.A.F., would like to thank the Alistore ERI. L.S. received funds from the Ministry of Ecological Transition in the “Ricerca di Sistema Elettrico” framework. S.A.F. is indebted to ISTA for support. The Scientific Service Units of ISTA supported this research through resources provided by the Lab Support Facility and the Miba Machine Shop.","date_published":"2026-01-12T00:00:00Z","publication_identifier":{"eissn":["2574-0962"]},"OA_place":"publisher"},{"OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"_id":"21041","file":[{"success":1,"date_created":"2026-02-12T13:51:03Z","content_type":"application/pdf","date_updated":"2026-02-12T13:51:03Z","access_level":"open_access","checksum":"79be391061efbf9542638996959ce11a","file_name":"2026_ProcACMProgrammingLanguages_Mueck.pdf","relation":"main_file","file_size":1058876,"creator":"dernst","file_id":"21221"}],"ddc":["000"],"intvolume":"        10","scopus_import":"1","doi":"10.1145/3776682","publication_status":"published","status":"public","date_updated":"2026-02-12T13:53:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"1153-1182","oa_version":"Published Version","PlanS_conform":"1","type":"journal_article","article_type":"original","title":"Endangered by the language but saved by the compiler: Robust safety via semantic back-translation","department":[{"_id":"MiSa"}],"has_accepted_license":"1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"Association for Computing Machinery","publication_identifier":{"eissn":["2475-1421"]},"OA_place":"publisher","file_date_updated":"2026-02-12T13:51:03Z","date_published":"2026-01-08T00:00:00Z","publication":"Proceedings of the ACM on Programming Languages","citation":{"ama":"Mück N, Georges AL, Dreyer D, Garg D, Sammler MJ. Endangered by the language but saved by the compiler: Robust safety via semantic back-translation. <i>Proceedings of the ACM on Programming Languages</i>. 2026;10:1153-1182. doi:<a href=\"https://doi.org/10.1145/3776682\">10.1145/3776682</a>","mla":"Mück, Niklas, et al. “Endangered by the Language but Saved by the Compiler: Robust Safety via Semantic Back-Translation.” <i>Proceedings of the ACM on Programming Languages</i>, vol. 10, Association for Computing Machinery, 2026, pp. 1153–82, doi:<a href=\"https://doi.org/10.1145/3776682\">10.1145/3776682</a>.","ista":"Mück N, Georges AL, Dreyer D, Garg D, Sammler MJ. 2026. Endangered by the language but saved by the compiler: Robust safety via semantic back-translation. Proceedings of the ACM on Programming Languages. 10, 1153–1182.","ieee":"N. Mück, A. L. Georges, D. Dreyer, D. Garg, and M. J. Sammler, “Endangered by the language but saved by the compiler: Robust safety via semantic back-translation,” <i>Proceedings of the ACM on Programming Languages</i>, vol. 10. Association for Computing Machinery, pp. 1153–1182, 2026.","short":"N. Mück, A.L. Georges, D. Dreyer, D. Garg, M.J. Sammler, Proceedings of the ACM on Programming Languages 10 (2026) 1153–1182.","chicago":"Mück, Niklas, Aïna Linn Georges, Derek Dreyer, Deepak Garg, and Michael Joachim Sammler. “Endangered by the Language but Saved by the Compiler: Robust Safety via Semantic Back-Translation.” <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery, 2026. <a href=\"https://doi.org/10.1145/3776682\">https://doi.org/10.1145/3776682</a>.","apa":"Mück, N., Georges, A. L., Dreyer, D., Garg, D., &#38; Sammler, M. J. (2026). Endangered by the language but saved by the compiler: Robust safety via semantic back-translation. <i>Proceedings of the ACM on Programming Languages</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3776682\">https://doi.org/10.1145/3776682</a>"},"abstract":[{"text":"It is common for programmers to assemble their programs from a combination of trusted and untrusted components. In this context, a trusted program component is said to be robustly safe if it behaves safely when linked against arbitrary untrusted code. Prior work has shown how various encapsulation mechanisms (in both high- and low-level languages) can be used to protect code so that it is robustly safe, but none of the existing work has explored how robust safety can be achieved in a patently unsafe language like C.\r\nIn this paper, we show how to bring robust safety to a simple yet representative C-like language we call Rec. Although Rec (like C) is inherently ”dangerous” and thus not robustly safe, we can ”save” Rec programs via compilation to Cap, a CHERI-like capability machine. To formalize the benefits of such a hardening compiler, we develop Reckon, a separation logic for verifying robust safety of Rec programs. Reckon is not sound under Rec’s unsafe, C-like semantics, but it is sound when Rec programs are hardened via compilation and linked against untrusted code running on Cap. As a crucial step in proving soundness of Reckon, we introduce a novel technique of semantic back-translation, which we formalize by building on the DimSum framework for multi-language semantics. All our results are mechanized in the Rocq prover.","lang":"eng"}],"month":"01","author":[{"first_name":"Niklas","last_name":"Mück","full_name":"Mück, Niklas"},{"full_name":"Georges, Aïna Linn","first_name":"Aïna Linn","last_name":"Georges"},{"full_name":"Dreyer, Derek","last_name":"Dreyer","first_name":"Derek"},{"last_name":"Garg","first_name":"Deepak","full_name":"Garg, Deepak"},{"last_name":"Sammler","first_name":"Michael Joachim","id":"510d3901-2a03-11ee-914d-d9ae9011f0a7","full_name":"Sammler, Michael Joachim"}],"quality_controlled":"1","oa":1,"date_created":"2026-01-25T23:01:40Z","year":"2026","day":"08","volume":10},{"type":"conference","oa_version":"Preprint","title":"Anthemius: Efficient and modular block assembly for concurrent execution","department":[{"_id":"KrPi"}],"arxiv":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"307-323","project":[{"_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502","name":"Interface Theory for Security and Privacy"},{"grant_number":"ICT22-045","name":"SeCure, privAte, and interoperabLe layEr 2","_id":"7bdd2f70-9f16-11ee-852c-b7950bc6d277"}],"intvolume":"     15751","scopus_import":"1","doi":"10.1007/978-3-032-07024-1_18","status":"public","publication_status":"published","conference":{"name":"FC: Financial Cryptography and Data Security","end_date":"2025-04-18","start_date":"2025-04-14","location":"Miyakojima, Japan"},"date_updated":"2026-02-12T13:39:07Z","language":[{"iso":"eng"}],"article_processing_charge":"No","OA_type":"green","_id":"21042","alternative_title":["LNCS"],"date_created":"2026-01-25T23:01:40Z","day":"01","year":"2026","volume":15751,"month":"01","quality_controlled":"1","author":[{"full_name":"Neiheiser, Ray","orcid":"0000-0001-7227-8309","id":"f09651b9-fec0-11ec-b5d8-934aff0e52a4","last_name":"Neiheiser","first_name":"Ray"},{"full_name":"Kokoris Kogias, Eleftherios","last_name":"Kokoris Kogias","first_name":"Eleftherios","id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30","orcid":"0000-0002-8827-3382"}],"oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2502.10074"}],"publication":"29th International Conference on Financial Cryptography and Data Security","citation":{"apa":"Neiheiser, R., &#38; Kokoris Kogias, E. (2026). Anthemius: Efficient and modular block assembly for concurrent execution. In <i>29th International Conference on Financial Cryptography and Data Security</i> (Vol. 15751, pp. 307–323). Miyakojima, Japan: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-07024-1_18\">https://doi.org/10.1007/978-3-032-07024-1_18</a>","chicago":"Neiheiser, Ray, and Eleftherios Kokoris Kogias. “Anthemius: Efficient and Modular Block Assembly for Concurrent Execution.” In <i>29th International Conference on Financial Cryptography and Data Security</i>, 15751:307–23. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-07024-1_18\">https://doi.org/10.1007/978-3-032-07024-1_18</a>.","short":"R. Neiheiser, E. Kokoris Kogias, in:, 29th International Conference on Financial Cryptography and Data Security, Springer Nature, 2026, pp. 307–323.","ieee":"R. Neiheiser and E. Kokoris Kogias, “Anthemius: Efficient and modular block assembly for concurrent execution,” in <i>29th International Conference on Financial Cryptography and Data Security</i>, Miyakojima, Japan, 2026, vol. 15751, pp. 307–323.","ista":"Neiheiser R, Kokoris Kogias E. 2026. Anthemius: Efficient and modular block assembly for concurrent execution. 29th International Conference on Financial Cryptography and Data Security. FC: Financial Cryptography and Data Security, LNCS, vol. 15751, 307–323.","mla":"Neiheiser, Ray, and Eleftherios Kokoris Kogias. “Anthemius: Efficient and Modular Block Assembly for Concurrent Execution.” <i>29th International Conference on Financial Cryptography and Data Security</i>, vol. 15751, Springer Nature, 2026, pp. 307–23, doi:<a href=\"https://doi.org/10.1007/978-3-032-07024-1_18\">10.1007/978-3-032-07024-1_18</a>.","ama":"Neiheiser R, Kokoris Kogias E. Anthemius: Efficient and modular block assembly for concurrent execution. In: <i>29th International Conference on Financial Cryptography and Data Security</i>. Vol 15751. Springer Nature; 2026:307-323. doi:<a href=\"https://doi.org/10.1007/978-3-032-07024-1_18\">10.1007/978-3-032-07024-1_18</a>"},"abstract":[{"text":"Many blockchains such as Ethereum execute all incoming transactions sequentially significantly limiting the potential throughput. A common approach to scale execution is parallel execution engines that fully utilize modern multi-core architectures. Parallel execution is then either done optimistically, by executing transactions in parallel and detecting conflicts on the fly, or guided, by requiring exhaustive client transaction hints and scheduling transactions accordingly.\r\n\r\nHowever, recent studies have shown that the performance of parallel execution engines depends on the nature of the underlying workload. In fact, in some cases, only a 60% speed-up compared to sequential execution could be obtained. This is the case, as transactions that access the same resources must be executed sequentially. For example, if 10% of the transactions in a block access the same resource, the execution cannot meaningfully scale beyond 10 cores. Therefore, a single popular application can bottleneck the execution and limit the potential throughput.\r\n\r\nIn this paper, we introduce Anthemius, a block construction algorithm that optimizes parallel transaction execution throughput. We evaluate Anthemius exhaustively under a range of workloads, and show that Anthemius enables the underlying parallel execution engine to process over twice as many transactions.","lang":"eng"}],"corr_author":"1","publisher":"Springer Nature","external_id":{"arxiv":["2502.10074"]},"date_published":"2026-01-01T00:00:00Z","acknowledgement":"This work was supported by the Austrian Science Fund (FWF) SFB project SpyCoDe F8502 and the Vienna Science and Technology Fund (WWTF) project SCALE2 CT22-045.","OA_place":"repository","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783032070234"],"issn":["0302-9743"]}},{"abstract":[{"lang":"eng","text":"Scalability is a crucial requirement for modern large-scale systems, enabling elasticity and ensuring responsiveness under varying load. While cloud systems have achieved scalable architectures, blockchain systems remain constrained by the need to over-provision validator machines to handle peak load. This leads to resource inefficiency, poor cost scaling, and limits on performance. To address these challenges, we introduce Pilotfish, the first scale-out transaction execution engine for blockchains. Pilotfish enables validators to scale horizontally by distributing transaction execution across multiple worker machines, allowing elasticity without compromising consistency or determinism. It integrates seamlessly with the lazy blockchain architecture, completing the missing piece of execution elasticity. To achieve this, Pilotfish tackles several key challenges: ensuring scalable and strongly consistent distributed transactions, handling partial crash recovery with lightweight replication, and maintaining concurrency with a novel versioned-queue scheduling algorithm. Our evaluation shows that Pilotfish scales linearly up to at least eight workers per validator for compute-bound workloads, while maintaining low latency. By solving scalable execution, Pilotfish brings blockchains closer to achieving end-to-end elasticity, unlocking new possibilities for efficient and adaptable blockchain systems."}],"citation":{"mla":"Kniep, Quentin, et al. “Pilotfish: Distributed Execution for Scalable Blockchains.” <i>29th International Conference on Financial Cryptography and Data Security</i>, vol. 15751, Springer Nature, 2026, pp. 287–306, doi:<a href=\"https://doi.org/10.1007/978-3-032-07024-1_17\">10.1007/978-3-032-07024-1_17</a>.","ama":"Kniep Q, Kokoris Kogias E, Sonnino A, Zablotchi I, Zhang N. Pilotfish: Distributed execution for scalable blockchains. In: <i>29th International Conference on Financial Cryptography and Data Security</i>. Vol 15751. Springer Nature; 2026:287-306. doi:<a href=\"https://doi.org/10.1007/978-3-032-07024-1_17\">10.1007/978-3-032-07024-1_17</a>","ista":"Kniep Q, Kokoris Kogias E, Sonnino A, Zablotchi I, Zhang N. 2026. Pilotfish: Distributed execution for scalable blockchains. 29th International Conference on Financial Cryptography and Data Security. FC: Financial Cryptography and Data Security, LNCS, vol. 15751, 287–306.","ieee":"Q. Kniep, E. Kokoris Kogias, A. Sonnino, I. Zablotchi, and N. Zhang, “Pilotfish: Distributed execution for scalable blockchains,” in <i>29th International Conference on Financial Cryptography and Data Security</i>, Miyakojima, Japan, 2026, vol. 15751, pp. 287–306.","apa":"Kniep, Q., Kokoris Kogias, E., Sonnino, A., Zablotchi, I., &#38; Zhang, N. (2026). Pilotfish: Distributed execution for scalable blockchains. In <i>29th International Conference on Financial Cryptography and Data Security</i> (Vol. 15751, pp. 287–306). Miyakojima, Japan: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-07024-1_17\">https://doi.org/10.1007/978-3-032-07024-1_17</a>","short":"Q. Kniep, E. Kokoris Kogias, A. Sonnino, I. Zablotchi, N. Zhang, in:, 29th International Conference on Financial Cryptography and Data Security, Springer Nature, 2026, pp. 287–306.","chicago":"Kniep, Quentin, Eleftherios Kokoris Kogias, Alberto Sonnino, Igor Zablotchi, and Nuda Zhang. “Pilotfish: Distributed Execution for Scalable Blockchains.” In <i>29th International Conference on Financial Cryptography and Data Security</i>, 15751:287–306. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/978-3-032-07024-1_17\">https://doi.org/10.1007/978-3-032-07024-1_17</a>."},"publication":"29th International Conference on Financial Cryptography and Data Security","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2401.16292"}],"publication_identifier":{"eissn":["1611-3349"],"isbn":["9783032070234"],"issn":["0302-9743"]},"OA_place":"repository","date_published":"2026-01-01T00:00:00Z","external_id":{"arxiv":["2401.16292"]},"publisher":"Springer Nature","volume":15751,"year":"2026","day":"01","date_created":"2026-01-25T23:01:41Z","alternative_title":["LNCS"],"oa":1,"author":[{"first_name":"Quentin","last_name":"Kniep","full_name":"Kniep, Quentin"},{"full_name":"Kokoris Kogias, Eleftherios","last_name":"Kokoris Kogias","first_name":"Eleftherios","id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30","orcid":"0000-0002-8827-3382"},{"full_name":"Sonnino, Alberto","last_name":"Sonnino","first_name":"Alberto"},{"last_name":"Zablotchi","first_name":"Igor","full_name":"Zablotchi, Igor"},{"full_name":"Zhang, Nuda","last_name":"Zhang","first_name":"Nuda"}],"quality_controlled":"1","month":"01","date_updated":"2026-02-16T07:56:09Z","conference":{"name":"FC: Financial Cryptography and Data Security","end_date":"2025-04-18","start_date":"2025-04-14","location":"Miyakojima, Japan"},"publication_status":"published","status":"public","scopus_import":"1","doi":"10.1007/978-3-032-07024-1_17","intvolume":"     15751","_id":"21044","language":[{"iso":"eng"}],"OA_type":"green","article_processing_charge":"No","title":"Pilotfish: Distributed execution for scalable blockchains","oa_version":"Preprint","type":"conference","page":"287-306","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","arxiv":1}]