[{"doi":"10.1103/physrevlett.124.048102","citation":{"short":"A. Paraschiv, S. Hegde, R. Ganti, T. Pilizota, A. Šarić, Physical Review Letters 124 (2020).","chicago":"Paraschiv, Alexandru, Smitha Hegde, Raman Ganti, Teuta Pilizota, and Anđela Šarić. “Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels.” <i>Physical Review Letters</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/physrevlett.124.048102\">https://doi.org/10.1103/physrevlett.124.048102</a>.","ista":"Paraschiv A, Hegde S, Ganti R, Pilizota T, Šarić A. 2020. Dynamic clustering regulates activity of mechanosensitive membrane channels. Physical Review Letters. 124(4), 048102.","apa":"Paraschiv, A., Hegde, S., Ganti, R., Pilizota, T., &#38; Šarić, A. (2020). Dynamic clustering regulates activity of mechanosensitive membrane channels. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevlett.124.048102\">https://doi.org/10.1103/physrevlett.124.048102</a>","ama":"Paraschiv A, Hegde S, Ganti R, Pilizota T, Šarić A. Dynamic clustering regulates activity of mechanosensitive membrane channels. <i>Physical Review Letters</i>. 2020;124(4). doi:<a href=\"https://doi.org/10.1103/physrevlett.124.048102\">10.1103/physrevlett.124.048102</a>","ieee":"A. Paraschiv, S. Hegde, R. Ganti, T. Pilizota, and A. Šarić, “Dynamic clustering regulates activity of mechanosensitive membrane channels,” <i>Physical Review Letters</i>, vol. 124, no. 4. American Physical Society, 2020.","mla":"Paraschiv, Alexandru, et al. “Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels.” <i>Physical Review Letters</i>, vol. 124, no. 4, 048102, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/physrevlett.124.048102\">10.1103/physrevlett.124.048102</a>."},"scopus_import":"1","volume":124,"extern":"1","_id":"10353","main_file_link":[{"url":"https://www.biorxiv.org/content/10.1101/553248","open_access":"1"}],"oa_version":"Preprint","quality_controlled":"1","external_id":{"pmid":["32058787"]},"publication_identifier":{"eissn":["1079-7114"],"issn":["0031-9007"]},"article_type":"original","acknowledgement":"We thank Samantha Miller, Bert Poolman, and the members of Šarić and Pilizota laboratories for useful discussion. We acknowledge support from the Engineering and Physical Sciences Research Council (A.P. and A.Š.), the UCL Institute for the Physics of Living Systems (A.P. and A.Š.), Darwin Trust of University of Edinburgh (H.S.), Industrial Biotechnology Innovation Centre (H.S. and T.P.), BBSRC Council Crossing Biological Membrane Network (H.S. and T.P.), BBSRC/EPSRC/MRC Synthetic Biology Research Centre (T.P.), and the Royal Society (A.Š.).","day":"31","date_updated":"2021-11-26T11:21:12Z","title":"Dynamic clustering regulates activity of mechanosensitive membrane channels","author":[{"full_name":"Paraschiv, Alexandru","first_name":"Alexandru","last_name":"Paraschiv"},{"full_name":"Hegde, Smitha","last_name":"Hegde","first_name":"Smitha"},{"full_name":"Ganti, Raman","first_name":"Raman","last_name":"Ganti"},{"full_name":"Pilizota, Teuta","last_name":"Pilizota","first_name":"Teuta"},{"full_name":"Šarić, Anđela","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","first_name":"Anđela","last_name":"Šarić","orcid":"0000-0002-7854-2139"}],"language":[{"iso":"eng"}],"intvolume":"       124","date_created":"2021-11-26T09:57:01Z","pmid":1,"abstract":[{"lang":"eng","text":"Experiments have suggested that bacterial mechanosensitive channels separate into 2D clusters, the role of which is unclear. By developing a coarse-grained computer model we find that clustering promotes the channel closure, which is highly dependent on the channel concentration and membrane stress. This behaviour yields a tightly regulated gating system, whereby at high tensions channels gate individually, and at lower tensions the channels spontaneously aggregate and inactivate. We implement this positive feedback into the model for cell volume regulation, and find that the channel clustering protects the cell against excessive loss of cytoplasmic content."}],"publisher":"American Physical Society","publication":"Physical Review Letters","month":"01","status":"public","issue":"4","type":"journal_article","oa":1,"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-01-31T00:00:00Z","article_number":"048102","keyword":["general physics and astronomy"],"year":"2020","article_processing_charge":"No","publication_status":"published"},{"type":"conference","isi":1,"oa":1,"page":"1751–1767","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2020-10-30T00:00:00Z","article_processing_charge":"No","year":"2020","publication_status":"published","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"In this paper, we present the first Asynchronous Distributed Key Generation (ADKG) algorithm which is also the first distributed key generation algorithm that can generate cryptographic keys with a dual (f,2f+1)-threshold (where f is the number of faulty parties). As a result, using our ADKG we remove the trusted setup assumption that the most scalable consensus algorithms make. In order to create a DKG with a dual (f,2f+1)- threshold we first answer in the affirmative the open question posed by Cachin et al. [7] on how to create an Asynchronous Verifiable Secret Sharing (AVSS) protocol with a reconstruction threshold of f+1<k łe 2f+1, which is of independent interest. Our High-threshold-AVSS (HAVSS) uses an asymmetric bivariate polynomial to encode the secret. This enables the reconstruction of the secret only if a set of k nodes contribute while allowing an honest node that did not participate in the sharing phase to recover his share with the help of f+1 honest parties. Once we have HAVSS we can use it to bootstrap scalable partially synchronous consensus protocols, but the question on how to get a DKG in asynchrony remains as we need a way to produce common randomness. The solution comes from a novel Eventually Perfect Common Coin (EPCC) abstraction that enables the generation of a common coin from n concurrent HAVSS invocations. EPCC's key property is that it is eventually reliable, as it might fail to agree at most f times (even if invoked a polynomial number of times). Using EPCC we implement an Eventually Efficient Asynchronous Binary Agreement (EEABA) which is optimal when the EPCC agrees and protects safety when EPCC fails. Finally, using EEABA we construct the first ADKG which has the same overhead and expected runtime as the best partially-synchronous DKG (O(n4) words, O(f) rounds). As a corollary of our ADKG, we can also create the first Validated Asynchronous Byzantine Agreement (VABA) that does not need a trusted dealer to setup threshold signatures of degree n-f. Our VABA has an overhead of expected O(n2) words and O(1) time per instance, after an initial O(n4) words and O(f) time bootstrap via ADKG."}],"date_created":"2021-12-16T13:23:27Z","publisher":"Association for Computing Machinery","status":"public","month":"10","publication":"Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security","conference":{"start_date":"2020-11-09","name":"CCS: Conference on Computer and Communications Security","location":"Virtual, United States","end_date":"2020-11-13"},"external_id":{"isi":["000768470400104"]},"acknowledgement":"We would like to thank Ittai Abraham for the discussions and guidance during the initial conception of the project, especially for HAVSS. Furthermore, we would like to thank the anonymous reviewers for pointing out the relevance of this work to MPC protocols.","publication_identifier":{"isbn":["978-1-4503-7089-9"]},"day":"30","date_updated":"2025-07-10T11:49:52Z","title":"Asynchronous distributed key generation for computationally-secure randomness, consensus, and threshold signatures","author":[{"id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30","full_name":"Kokoris Kogias, Eleftherios","first_name":"Eleftherios","last_name":"Kokoris Kogias"},{"full_name":"Malkhi, Dahlia","last_name":"Malkhi","first_name":"Dahlia"},{"first_name":"Alexander","last_name":"Spiegelman","full_name":"Spiegelman, Alexander"}],"doi":"10.1145/3372297.3423364","citation":{"mla":"Kokoris Kogias, Eleftherios, et al. “Asynchronous Distributed Key Generation for Computationally-Secure Randomness, Consensus, and Threshold Signatures.” <i>Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security</i>, Association for Computing Machinery, 2020, pp. 1751–1767, doi:<a href=\"https://doi.org/10.1145/3372297.3423364\">10.1145/3372297.3423364</a>.","ieee":"E. Kokoris Kogias, D. Malkhi, and A. Spiegelman, “Asynchronous distributed key generation for computationally-secure randomness, consensus, and threshold signatures,” in <i>Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security</i>, Virtual, United States, 2020, pp. 1751–1767.","ama":"Kokoris Kogias E, Malkhi D, Spiegelman A. Asynchronous distributed key generation for computationally-secure randomness, consensus, and threshold signatures. In: <i>Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security</i>. Association for Computing Machinery; 2020:1751–1767. doi:<a href=\"https://doi.org/10.1145/3372297.3423364\">10.1145/3372297.3423364</a>","ista":"Kokoris Kogias E, Malkhi D, Spiegelman A. 2020. Asynchronous distributed key generation for computationally-secure randomness, consensus, and threshold signatures. Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security. CCS: Conference on Computer and Communications Security, 1751–1767.","apa":"Kokoris Kogias, E., Malkhi, D., &#38; Spiegelman, A. (2020). Asynchronous distributed key generation for computationally-secure randomness, consensus, and threshold signatures. In <i>Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security</i> (pp. 1751–1767). Virtual, United States: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3372297.3423364\">https://doi.org/10.1145/3372297.3423364</a>","chicago":"Kokoris Kogias, Eleftherios, Dahlia Malkhi, and Alexander Spiegelman. “Asynchronous Distributed Key Generation for Computationally-Secure Randomness, Consensus, and Threshold Signatures.” In <i>Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security</i>, 1751–1767. Association for Computing Machinery, 2020. <a href=\"https://doi.org/10.1145/3372297.3423364\">https://doi.org/10.1145/3372297.3423364</a>.","short":"E. Kokoris Kogias, D. Malkhi, A. Spiegelman, in:, Proceedings of the 2020 ACM SIGSAC Conference on Computer and Communications Security, Association for Computing Machinery, 2020, pp. 1751–1767."},"department":[{"_id":"ElKo"}],"scopus_import":"1","_id":"10556","main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2019/1015"}],"quality_controlled":"1","oa_version":"Preprint"},{"type":"patent","oa":1,"application_date":"2017-06-09","day":"03","related_material":{"link":[{"relation":"earlier_version","url":"https://patents.google.com/patent/US20180359096A1/en"}]},"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods","date_published":"2020-03-03T00:00:00Z","date_updated":"2021-12-21T10:04:50Z","article_processing_charge":"No","year":"2020","author":[{"last_name":"Ford","first_name":"Bryan","full_name":"Ford, Bryan"},{"first_name":"Linus","last_name":"Gasse","full_name":"Gasse, Linus"},{"full_name":"Kokoris Kogias, Eleftherios","id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30","last_name":"Kokoris Kogias","first_name":"Eleftherios"},{"last_name":"Jovanovic","first_name":"Philipp","full_name":"Jovanovic, Philipp"}],"ipn":"10581613","ipc":" H04L9/3247 ; G06Q20/29 ; G06Q20/382 ; H04L9/3236","citation":{"mla":"Ford, Bryan, et al. <i>Cryptographically Verifiable Data Structure Having Multi-Hop Forward and Backwards Links and Associated Systems and Methods</i>. 2020.","ieee":"B. Ford, L. Gasse, E. Kokoris Kogias, and P. Jovanovic, “Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods.” 2020.","ista":"Ford B, Gasse L, Kokoris Kogias E, Jovanovic P. 2020. Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods.","ama":"Ford B, Gasse L, Kokoris Kogias E, Jovanovic P. Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods. 2020.","apa":"Ford, B., Gasse, L., Kokoris Kogias, E., &#38; Jovanovic, P. (2020). Cryptographically verifiable data structure having multi-hop forward and backwards links and associated systems and methods.","chicago":"Ford, Bryan, Linus Gasse, Eleftherios Kokoris Kogias, and Philipp Jovanovic. “Cryptographically Verifiable Data Structure Having Multi-Hop Forward and Backwards Links and Associated Systems and Methods,” 2020.","short":"B. Ford, L. Gasse, E. Kokoris Kogias, P. Jovanovic, (2020)."},"date_created":"2021-12-16T13:28:59Z","department":[{"_id":"ElKo"}],"abstract":[{"text":"Data storage and retrieval systems, methods, and computer-readable media utilize a cryptographically verifiable data structure that facilitates verification of a transaction in a decentralized peer-to-peer environment using multi-hop backwards and forwards links. Backward links are cryptographic hashes of past records. Forward links are cryptographic signatures of future records that are added retroactively to records once the target block has been appended to the data structure.","lang":"eng"}],"extern":"1","_id":"10557","oa_version":"Published Version","month":"03","applicant":["Ecole Polytechnique Federale de Lausanne"],"status":"public","main_file_link":[{"url":"https://patents.google.com/patent/US10581613B2/en","open_access":"1"}],"publication_date":"2020-03-03"},{"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-11-23T00:00:00Z","publication_status":"published","keyword":["multidisciplinary"],"article_processing_charge":"No","year":"2020","type":"journal_article","oa":1,"page":"66-70","month":"11","publication":"Nature","status":"public","issue":"7836","language":[{"iso":"eng"}],"intvolume":"       588","date_created":"2022-01-13T14:12:17Z","pmid":1,"abstract":[{"text":"Magnetism typically arises from the joint effect of Fermi statistics and repulsive Coulomb interactions, which favours ground states with non-zero electron spin. As a result, controlling spin magnetism with electric fields—a longstanding technological goal in spintronics and multiferroics1,2—can be achieved only indirectly. Here we experimentally demonstrate direct electric-field control of magnetic states in an orbital Chern insulator3,4,5,6, a magnetic system in which non-trivial band topology favours long-range order of orbital angular momentum but the spins are thought to remain disordered7,8,9,10,11,12,13,14. We use van der Waals heterostructures consisting of a graphene monolayer rotationally faulted with respect to a Bernal-stacked bilayer to realize narrow and topologically non-trivial valley-projected moiré minibands15,16,17. At fillings of one and three electrons per moiré unit cell within these bands, we observe quantized anomalous Hall effects18 with transverse resistance approximately equal to h/2e2 (where h is Planck’s constant and e is the charge on the electron), which is indicative of spontaneous polarization of the system into a single-valley-projected band with a Chern number equal to two. At a filling of three electrons per moiré unit cell, we find that the sign of the quantum anomalous Hall effect can be reversed via field-effect control of the chemical potential; moreover, this transition is hysteretic, which we use to demonstrate non-volatile electric-field-induced reversal of the magnetic state. A theoretical analysis19 indicates that the effect arises from the topological edge states, which drive a change in sign of the magnetization and thus a reversal in the favoured magnetic state. Voltage control of magnetic states can be used to electrically pattern non-volatile magnetic-domain structures hosting chiral edge states, with applications ranging from reconfigurable microwave circuit elements to ultralow-power magnetic memories.","lang":"eng"}],"publisher":"Springer Nature","title":"Electrical switching of magnetic order in an orbital Chern insulator","date_updated":"2022-01-13T14:21:04Z","author":[{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"first_name":"J.","last_name":"Zhu","full_name":"Zhu, J."},{"full_name":"Kumar, M. A.","first_name":"M. A.","last_name":"Kumar"},{"full_name":"Zhang, Y.","first_name":"Y.","last_name":"Zhang"},{"first_name":"F.","last_name":"Yang","full_name":"Yang, F."},{"last_name":"Tschirhart","first_name":"C. L.","full_name":"Tschirhart, C. L."},{"last_name":"Serlin","first_name":"M.","full_name":"Serlin, M."},{"last_name":"Watanabe","first_name":"K.","full_name":"Watanabe, K."},{"full_name":"Taniguchi, T.","last_name":"Taniguchi","first_name":"T."},{"full_name":"MacDonald, A. H.","first_name":"A. H.","last_name":"MacDonald"},{"full_name":"Young, A. F.","first_name":"A. F.","last_name":"Young"}],"external_id":{"pmid":["33230333"],"arxiv":["2004.11353"]},"day":"23","article_type":"original","acknowledgement":"We acknowledge discussions with J. Checkelsky, S. Chen, C. Dean, M. Yankowitz, D. Reilly, I. Sodemann and M. Zaletel. Work at UCSB was primarily supported by the ARO under MURI W911NF-16-1-0361. Measurements of twisted bilayer graphene (Extended Data Fig. 8) and measurements at elevated temperatures (Extended Data Fig. 3) were supported by a SEED grant and made use of shared facilities of the UCSB MRSEC (NSF DMR 1720256), a member of the Materials Research Facilities Network (www.mrfn.org). A.F.Y. acknowledges the support of the David and Lucille Packard Foundation under award 2016-65145. A.H.M. and J.Z. were supported by the National Science Foundation through the Center for Dynamics and Control of Materials, an NSF MRSEC under Cooperative Agreement number DMR-1720595, and by the Welch Foundation under grant TBF1473. C.L.T. acknowledges support from the Hertz Foundation and from the National Science Foundation Graduate Research Fellowship Program under grant 1650114. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by the MEXT, Japan, Grant Number JPMXP0112101001, JSPS KAKENHI grant numbers JP20H00354 and the CREST(JPMJCR15F3), JST.","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"arxiv":1,"extern":"1","_id":"10618","oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/2004.11353","open_access":"1"}],"doi":"10.1038/s41586-020-2963-8","citation":{"short":"H. Polshyn, J. Zhu, M.A. Kumar, Y. Zhang, F. Yang, C.L. Tschirhart, M. Serlin, K. Watanabe, T. Taniguchi, A.H. MacDonald, A.F. Young, Nature 588 (2020) 66–70.","chicago":"Polshyn, Hryhoriy, J. Zhu, M. A. Kumar, Y. Zhang, F. Yang, C. L. Tschirhart, M. Serlin, et al. “Electrical Switching of Magnetic Order in an Orbital Chern Insulator.” <i>Nature</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41586-020-2963-8\">https://doi.org/10.1038/s41586-020-2963-8</a>.","ama":"Polshyn H, Zhu J, Kumar MA, et al. Electrical switching of magnetic order in an orbital Chern insulator. <i>Nature</i>. 2020;588(7836):66-70. doi:<a href=\"https://doi.org/10.1038/s41586-020-2963-8\">10.1038/s41586-020-2963-8</a>","apa":"Polshyn, H., Zhu, J., Kumar, M. A., Zhang, Y., Yang, F., Tschirhart, C. L., … Young, A. F. (2020). Electrical switching of magnetic order in an orbital Chern insulator. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-020-2963-8\">https://doi.org/10.1038/s41586-020-2963-8</a>","ista":"Polshyn H, Zhu J, Kumar MA, Zhang Y, Yang F, Tschirhart CL, Serlin M, Watanabe K, Taniguchi T, MacDonald AH, Young AF. 2020. Electrical switching of magnetic order in an orbital Chern insulator. Nature. 588(7836), 66–70.","ieee":"H. Polshyn <i>et al.</i>, “Electrical switching of magnetic order in an orbital Chern insulator,” <i>Nature</i>, vol. 588, no. 7836. Springer Nature, pp. 66–70, 2020.","mla":"Polshyn, Hryhoriy, et al. “Electrical Switching of Magnetic Order in an Orbital Chern Insulator.” <i>Nature</i>, vol. 588, no. 7836, Springer Nature, 2020, pp. 66–70, doi:<a href=\"https://doi.org/10.1038/s41586-020-2963-8\">10.1038/s41586-020-2963-8</a>."},"scopus_import":"1","volume":588},{"title":"The future of the correlated electron problem","date_published":"2020-10-01T00:00:00Z","date_updated":"2022-01-24T08:05:51Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"first_name":"A","last_name":"Alexandradinata","full_name":"Alexandradinata, A"},{"full_name":"Armitage, N.P.","first_name":"N.P.","last_name":"Armitage"},{"full_name":"Baydin, Andrey","last_name":"Baydin","first_name":"Andrey"},{"full_name":"Bi, Wenli","last_name":"Bi","first_name":"Wenli"},{"last_name":"Cao","first_name":"Yue","full_name":"Cao, Yue"},{"first_name":"Hitesh J.","last_name":"Changlani","full_name":"Changlani, Hitesh J."},{"last_name":"Chertkov","first_name":"Eli","full_name":"Chertkov, Eli"},{"full_name":"da Silva Neto, Eduardo H.","last_name":"da Silva Neto","first_name":"Eduardo H."},{"full_name":"Delacretaz, Luca","last_name":"Delacretaz","first_name":"Luca"},{"first_name":"Ismail","last_name":"El Baggari","full_name":"El Baggari, Ismail"},{"first_name":"G.M.","last_name":"Ferguson","full_name":"Ferguson, G.M."},{"full_name":"Gannon, William J.","first_name":"William J.","last_name":"Gannon"},{"first_name":"Sayed Ali Akbar","last_name":"Ghorashi","full_name":"Ghorashi, Sayed Ali Akbar"},{"first_name":"Berit H.","last_name":"Goodge","full_name":"Goodge, Berit H."},{"first_name":"Olga","last_name":"Goulko","full_name":"Goulko, Olga"},{"first_name":"G.","last_name":"Grissonnache","full_name":"Grissonnache, G."},{"full_name":"Hallas, Alannah","first_name":"Alannah","last_name":"Hallas"},{"full_name":"Hayes, Ian M.","first_name":"Ian M.","last_name":"Hayes"},{"full_name":"He, Yu","last_name":"He","first_name":"Yu"},{"full_name":"Huang, Edwin W.","last_name":"Huang","first_name":"Edwin W."},{"first_name":"Anshu","last_name":"Kogar","full_name":"Kogar, Anshu"},{"full_name":"Kumah, Divine","last_name":"Kumah","first_name":"Divine"},{"last_name":"Lee","first_name":"Jong Yeon","full_name":"Lee, Jong Yeon"},{"full_name":"Legros, A.","first_name":"A.","last_name":"Legros"},{"first_name":"Fahad","last_name":"Mahmood","full_name":"Mahmood, Fahad"},{"full_name":"Maximenko, Yulia","last_name":"Maximenko","first_name":"Yulia"},{"full_name":"Pellatz, Nick","first_name":"Nick","last_name":"Pellatz"},{"last_name":"Polshyn","orcid":"0000-0001-8223-8896","first_name":"Hryhoriy","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"full_name":"Sarkar, Tarapada","first_name":"Tarapada","last_name":"Sarkar"},{"full_name":"Scheie, Allen","first_name":"Allen","last_name":"Scheie"},{"first_name":"Kyle L.","last_name":"Seyler","full_name":"Seyler, Kyle L."},{"full_name":"Shi, Zhenzhong","last_name":"Shi","first_name":"Zhenzhong"},{"full_name":"Skinner, Brian","first_name":"Brian","last_name":"Skinner"},{"full_name":"Steinke, Lucia","last_name":"Steinke","first_name":"Lucia"},{"full_name":"Thirunavukkuarasu, K.","first_name":"K.","last_name":"Thirunavukkuarasu"},{"full_name":"Trevisan, Thaís Victa","first_name":"Thaís Victa","last_name":"Trevisan"},{"full_name":"Vogl, Michael","last_name":"Vogl","first_name":"Michael"},{"full_name":"Volkov, Pavel A.","first_name":"Pavel A.","last_name":"Volkov"},{"full_name":"Wang, Yao","last_name":"Wang","first_name":"Yao"},{"first_name":"Yishu","last_name":"Wang","full_name":"Wang, Yishu"},{"full_name":"Wei, Di","last_name":"Wei","first_name":"Di"},{"last_name":"Wei","first_name":"Kaya","full_name":"Wei, Kaya"},{"full_name":"Yang, Shuolong","first_name":"Shuolong","last_name":"Yang"},{"first_name":"Xian","last_name":"Zhang","full_name":"Zhang, Xian"},{"last_name":"Zhang","first_name":"Ya-Hui","full_name":"Zhang, Ya-Hui"},{"last_name":"Zhao","first_name":"Liuyan","full_name":"Zhao, Liuyan"},{"full_name":"Zong, Alfred","first_name":"Alfred","last_name":"Zong"}],"publication_status":"submitted","article_processing_charge":"No","year":"2020","oa":1,"external_id":{"arxiv":["2010.00584"]},"type":"preprint","page":"55","arxiv":1,"day":"01","acknowledgement":"We thank NSF CMP program for suggestions regarding the topic and general structure of the workshop. This project was supported by the NSF DMR-2002329 and The Gordon and Betty Moore Foundation (GBMF) EPiQS initiative. We would like to sincerely thank A. Kapitulnik, A. J. Leggett, M.B. Maple, T.M. McQueen, M. Norman, P. S. Riseborough, and G. A. Sawatzky for their lectures at the workshop and advice on the writing of this manuscript. We would also like to thank G. Blumberg, C. Broholm, S. Crooker, N. Drichko, and A. Patel for helpful consultation on topics discussed\r\nherein. A number of individuals also had independent support: (AA, EH; GBMF-4305), (IMH; GBMF-9071), (HJC; NHMFL is supported by the NSF DMR-1644779 and the state of Florida), (YH, AZ; Miller Institute for Basic Research in Science), (YC; US DOE-BES DEAC02-06CH11357), (AS; Spallation Neutron Source, a DOE Office of Science User Facility operated by ORNL), (SAAG; ARO-W911NF-18-1-0290, NSF DMR-1455233), (YW; DOE-BES DE-SC0019331, GBMF-4532).","publication":"arXiv","month":"10","oa_version":"Preprint","status":"public","main_file_link":[{"url":"https://arxiv.org/abs/2010.00584","open_access":"1"}],"extern":"1","_id":"10650","citation":{"short":"A. Alexandradinata, N.P. Armitage, A. Baydin, W. Bi, Y. Cao, H.J. Changlani, E. Chertkov, E.H. da Silva Neto, L. Delacretaz, I. El Baggari, G.M. Ferguson, W.J. Gannon, S.A.A. Ghorashi, B.H. Goodge, O. Goulko, G. Grissonnache, A. Hallas, I.M. Hayes, Y. He, E.W. Huang, A. Kogar, D. Kumah, J.Y. Lee, A. Legros, F. Mahmood, Y. Maximenko, N. Pellatz, H. Polshyn, T. Sarkar, A. Scheie, K.L. Seyler, Z. Shi, B. Skinner, L. Steinke, K. Thirunavukkuarasu, T.V. Trevisan, M. Vogl, P.A. Volkov, Y. Wang, Y. Wang, D. Wei, K. Wei, S. Yang, X. Zhang, Y.-H. Zhang, L. Zhao, A. Zong, ArXiv (n.d.).","chicago":"Alexandradinata, A, N.P. Armitage, Andrey Baydin, Wenli Bi, Yue Cao, Hitesh J. Changlani, Eli Chertkov, et al. “The Future of the Correlated Electron Problem.” <i>ArXiv</i>, n.d.","apa":"Alexandradinata, A., Armitage, N. P., Baydin, A., Bi, W., Cao, Y., Changlani, H. J., … Zong, A. (n.d.). The future of the correlated electron problem. <i>arXiv</i>.","ista":"Alexandradinata A, Armitage NP, Baydin A, Bi W, Cao Y, Changlani HJ, Chertkov E, da Silva Neto EH, Delacretaz L, El Baggari I, Ferguson GM, Gannon WJ, Ghorashi SAA, Goodge BH, Goulko O, Grissonnache G, Hallas A, Hayes IM, He Y, Huang EW, Kogar A, Kumah D, Lee JY, Legros A, Mahmood F, Maximenko Y, Pellatz N, Polshyn H, Sarkar T, Scheie A, Seyler KL, Shi Z, Skinner B, Steinke L, Thirunavukkuarasu K, Trevisan TV, Vogl M, Volkov PA, Wang Y, Wang Y, Wei D, Wei K, Yang S, Zhang X, Zhang Y-H, Zhao L, Zong A. The future of the correlated electron problem. arXiv, .","ama":"Alexandradinata A, Armitage NP, Baydin A, et al. The future of the correlated electron problem. <i>arXiv</i>.","ieee":"A. Alexandradinata <i>et al.</i>, “The future of the correlated electron problem,” <i>arXiv</i>. .","mla":"Alexandradinata, A., et al. “The Future of the Correlated Electron Problem.” <i>ArXiv</i>."},"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"The understanding of material systems with strong electron-electron interactions is the central problem in modern condensed matter physics. Despite this, the essential physics of many of these materials is still not understood and we have no overall perspective on their properties. Moreover, we have very little ability to make predictions in this class of systems. In this manuscript we share our personal views of what the major open problems are in correlated electron systems and we discuss some possible routes to make progress in this rich and fascinating field. This manuscript is the result of the vigorous discussions and deliberations that took place at Johns Hopkins University during a three-day workshop January 27, 28, and 29, 2020 that brought together six senior scientists and 46 more junior scientists. Our hope, is that the topics we have presented will provide inspiration for others working in this field and motivation for the idea that significant progress can be made on very hard problems if we focus our collective energies."}],"date_created":"2022-01-20T10:55:36Z"},{"language":[{"iso":"eng"}],"publisher":"ICLR","has_accepted_license":"1","abstract":[{"lang":"eng","text":"The family of feedback alignment (FA) algorithms aims to provide a more biologically motivated alternative to backpropagation (BP), by substituting the computations that are unrealistic to be implemented in physical brains. While FA algorithms have been shown to work well in practice, there is a lack of rigorous theory proofing their learning capabilities. Here we introduce the first feedback alignment algorithm with provable learning guarantees. In contrast to existing work, we do not require any assumption about the size or depth of the network except that it has a single output neuron, i.e., such as for binary classification tasks. We show that our FA algorithm can deliver its theoretical promises in practice, surpassing the learning performance of existing FA methods and matching backpropagation in binary classification tasks. Finally, we demonstrate the limits of our FA variant when the number of output neurons grows beyond a certain quantity."}],"date_created":"2022-01-25T15:50:00Z","corr_author":"1","ddc":["000"],"month":"03","status":"public","publication":"8th International Conference on Learning Representations","oa":1,"type":"conference","date_published":"2020-03-11T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"success":1,"file_id":"10677","date_updated":"2022-01-26T07:35:17Z","file_name":"iclr_2020.pdf","creator":"mlechner","checksum":"ea13d42dd4541ddb239b6a75821fd6c9","relation":"main_file","date_created":"2022-01-26T07:35:17Z","content_type":"application/pdf","access_level":"open_access","file_size":249431}],"year":"2020","article_processing_charge":"No","publication_status":"published","citation":{"mla":"Lechner, Mathias. “Learning Representations for Binary-Classification without Backpropagation.” <i>8th International Conference on Learning Representations</i>, ICLR, 2020.","ieee":"M. Lechner, “Learning representations for binary-classification without backpropagation,” in <i>8th International Conference on Learning Representations</i>, Virtual ; Addis Ababa, Ethiopia, 2020.","ama":"Lechner M. Learning representations for binary-classification without backpropagation. In: <i>8th International Conference on Learning Representations</i>. ICLR; 2020.","ista":"Lechner M. 2020. Learning representations for binary-classification without backpropagation. 8th International Conference on Learning Representations. ICLR: International Conference on Learning Representations.","apa":"Lechner, M. (2020). Learning representations for binary-classification without backpropagation. In <i>8th International Conference on Learning Representations</i>. Virtual ; Addis Ababa, Ethiopia: ICLR.","chicago":"Lechner, Mathias. “Learning Representations for Binary-Classification without Backpropagation.” In <i>8th International Conference on Learning Representations</i>. ICLR, 2020.","short":"M. Lechner, in:, 8th International Conference on Learning Representations, ICLR, 2020."},"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","short":"CC BY-NC-ND (3.0)"},"project":[{"_id":"25F42A32-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"Z211","name":"Formal methods for the design and analysis of complex systems"}],"department":[{"_id":"GradSch"},{"_id":"ToHe"}],"scopus_import":"1","main_file_link":[{"url":"https://openreview.net/forum?id=Bke61krFvS","open_access":"1"}],"oa_version":"Published Version","quality_controlled":"1","_id":"10672","license":"https://creativecommons.org/licenses/by-nc-nd/3.0/","conference":{"end_date":"2020-05-01","start_date":"2020-04-26","name":"ICLR: International Conference on Learning Representations","location":"Virtual ; Addis Ababa, Ethiopia"},"acknowledgement":"This research was supported in part by the Austrian Science Fund (FWF) under grant Z211-N23\r\n(Wittgenstein Award).\r\n","file_date_updated":"2022-01-26T07:35:17Z","day":"11","date_updated":"2025-04-15T06:25:56Z","title":"Learning representations for binary-classification without backpropagation","author":[{"full_name":"Lechner, Mathias","id":"3DC22916-F248-11E8-B48F-1D18A9856A87","first_name":"Mathias","last_name":"Lechner"}]},{"ddc":["000"],"status":"public","publication":"Proceedings of the 37th International Conference on Machine Learning","language":[{"iso":"eng"}],"alternative_title":["PMLR"],"has_accepted_license":"1","date_created":"2022-01-25T15:50:34Z","abstract":[{"lang":"eng","text":"We propose a neural information processing system obtained by re-purposing the function of a biological neural circuit model to govern simulated and real-world control tasks. Inspired by the structure of the nervous system of the soil-worm, C. elegans, we introduce ordinary neural circuits (ONCs), defined as the model of biological neural circuits reparameterized for the control of alternative tasks. We first demonstrate that ONCs realize networks with higher maximum flow compared to arbitrary wired networks. We then learn instances of ONCs to control a series of robotic tasks, including the autonomous parking of a real-world rover robot. For reconfiguration of the purpose of the neural circuit, we adopt a search-based optimization algorithm. Ordinary neural circuits perform on par and, in some cases, significantly surpass the performance of contemporary deep learning models. ONC networks are compact, 77% sparser than their counterpart neural controllers, and their neural dynamics are fully interpretable at the cell-level."}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-01-01T00:00:00Z","year":"2020","article_processing_charge":"No","publication_status":"published","file":[{"relation":"main_file","date_created":"2022-01-26T11:08:51Z","checksum":"c9a4a29161777fc1a89ef451c040e3b1","file_name":"2020_PMLR_Hasani.pdf","creator":"cchlebak","file_size":2329798,"content_type":"application/pdf","access_level":"open_access","success":1,"file_id":"10691","date_updated":"2022-01-26T11:08:51Z"}],"series_title":"PMLR","type":"conference","oa":1,"page":"4082-4093","_id":"10673","main_file_link":[{"open_access":"1","url":"http://proceedings.mlr.press/v119/hasani20a.html"}],"oa_version":"Published Version","quality_controlled":"1","project":[{"grant_number":"Z211","name":"Formal methods for the design and analysis of complex systems","_id":"25F42A32-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"citation":{"mla":"Hasani, Ramin, et al. “A Natural Lottery Ticket Winner: Reinforcement Learning with Ordinary Neural Circuits.” <i>Proceedings of the 37th International Conference on Machine Learning</i>, 2020, pp. 4082–93.","ieee":"R. Hasani, M. Lechner, A. Amini, D. Rus, and R. Grosu, “A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits,” in <i>Proceedings of the 37th International Conference on Machine Learning</i>, Virtual, 2020, pp. 4082–4093.","ista":"Hasani R, Lechner M, Amini A, Rus D, Grosu R. 2020. A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. Proceedings of the 37th International Conference on Machine Learning. ML: Machine LearningPMLR, PMLR, , 4082–4093.","apa":"Hasani, R., Lechner, M., Amini, A., Rus, D., &#38; Grosu, R. (2020). A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. In <i>Proceedings of the 37th International Conference on Machine Learning</i> (pp. 4082–4093). Virtual.","ama":"Hasani R, Lechner M, Amini A, Rus D, Grosu R. A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits. In: <i>Proceedings of the 37th International Conference on Machine Learning</i>. PMLR. ; 2020:4082-4093.","chicago":"Hasani, Ramin, Mathias Lechner, Alexander Amini, Daniela Rus, and Radu Grosu. “A Natural Lottery Ticket Winner: Reinforcement Learning with Ordinary Neural Circuits.” In <i>Proceedings of the 37th International Conference on Machine Learning</i>, 4082–93. PMLR, 2020.","short":"R. Hasani, M. Lechner, A. Amini, D. Rus, R. Grosu, in:, Proceedings of the 37th International Conference on Machine Learning, 2020, pp. 4082–4093."},"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode","short":"CC BY-NC-ND (3.0)"},"department":[{"_id":"GradSch"},{"_id":"ToHe"}],"scopus_import":"1","date_updated":"2025-04-15T06:25:56Z","title":"A natural lottery ticket winner: Reinforcement learning with ordinary neural circuits","author":[{"full_name":"Hasani, Ramin","last_name":"Hasani","first_name":"Ramin"},{"first_name":"Mathias","last_name":"Lechner","full_name":"Lechner, Mathias","id":"3DC22916-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Amini","first_name":"Alexander","full_name":"Amini, Alexander"},{"full_name":"Rus, Daniela","first_name":"Daniela","last_name":"Rus"},{"last_name":"Grosu","first_name":"Radu","full_name":"Grosu, Radu"}],"conference":{"start_date":"2020-07-12","location":"Virtual","name":"ML: Machine Learning","end_date":"2020-07-18"},"file_date_updated":"2022-01-26T11:08:51Z","publication_identifier":{"issn":["2640-3498"]},"acknowledgement":"RH and RG are partially supported by Horizon-2020 ECSEL Project grant No. 783163 (iDev40), Productive 4.0, and ATBMBFW CPS-IoT Ecosystem. ML was supported in part by the Austrian Science Fund (FWF) under grant Z211-N23\r\n(Wittgenstein Award). AA is supported by the National Science Foundation (NSF) Graduate Research Fellowship\r\nProgram. RH and DR are partially supported by The Boeing Company and JP Morgan Chase. This research work is\r\npartially drawn from the PhD dissertation of RH.\r\n"},{"conference":{"end_date":"2020-03-06","name":"APS: American Physical Society","location":"Denver, CO, United States","start_date":"2020-03-02"},"publication_identifier":{"issn":["0003-0503"]},"day":"01","date_updated":"2022-01-27T10:58:38Z","title":"Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order","author":[{"last_name":"Zhou","first_name":"Haoxin","full_name":"Zhou, Haoxin"},{"first_name":"Hryhoriy","orcid":"0000-0001-8223-8896","last_name":"Polshyn","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy"},{"first_name":"Takashi","last_name":"Tanaguchi","full_name":"Tanaguchi, Takashi"},{"full_name":"Watanabe, Kenji","last_name":"Watanabe","first_name":"Kenji"},{"first_name":"Andrea","last_name":"Young","full_name":"Young, Andrea"}],"citation":{"ista":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. 2020. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B54. 00007.","ama":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Zhou, H., Polshyn, H., Tanaguchi, T., Watanabe, K., &#38; Young, A. (2020). Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Zhou, Haoxin, et al. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B54. 00007, American Physical Society, 2020.","ieee":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, and A. Young, “Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","short":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Tanaguchi, Kenji Watanabe, and Andrea Young. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020."},"volume":65,"_id":"10693","extern":"1","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B54.7"}],"quality_controlled":"1","oa_version":"Published Version","type":"conference","oa":1,"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-03-01T00:00:00Z","article_number":"B54. 00007","article_processing_charge":"No","year":"2020","publication_status":"published","language":[{"iso":"eng"}],"intvolume":"        65","alternative_title":["Bulletin of the American Physical Society"],"abstract":[{"lang":"eng","text":"High quality graphene heterostructures host an array of fractional quantum Hall isospin ferromagnets with diverse spin and valley orders. While a variety of phase transitions have been observed, disentangling the isospin phase diagram of these states is hampered by the absence of direct probes of spin and valley order. I will describe nonlocal transport measurements based on launching spin waves from a gate defined lateral heterojunction, performed in ultra-clean Corbino geometry graphene devices. At high magnetic fields, we find that the spin-wave transport signal is detected in all FQH states between ν = 0 and 1; however, between ν = 1 and 2 only odd numerator FQH states show finite nonlocal transport, despite the identical ground state spin polarizations in odd- and even numerator states. The results reveal that the neutral spin-waves are both spin and sublattice polarized making them a sensitive probe of ground state sublattice structure. Armed with this understanding, we use nonlocal transport signal to a magnetic field tuned isospin phase transition, showing that the emergent even denominator state at ν = 1/2 in monolayer graphene is indeed a multicomponent state featuring equal populations on each sublattice."}],"date_created":"2022-01-27T10:50:10Z","publisher":"American Physical Society","publication":"APS March Meeting 2020","status":"public","month":"03","issue":"1"},{"author":[{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"first_name":"Jihang","last_name":"Zhu","full_name":"Zhu, Jihang"},{"full_name":"Kumar, Manish","first_name":"Manish","last_name":"Kumar"},{"full_name":"Taniguchi, Takashi","last_name":"Taniguchi","first_name":"Takashi"},{"last_name":"Watanabe","first_name":"Kenji","full_name":"Watanabe, Kenji"},{"first_name":"Allan","last_name":"MacDonald","full_name":"MacDonald, Allan"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"date_updated":"2022-02-08T10:22:08Z","title":"Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures","publication_identifier":{"issn":["0003-0503"]},"day":"01","conference":{"end_date":"2020-03-06","name":"APS: American Physical Society","location":"Denver, CO, United States","start_date":"2020-03-02"},"_id":"10696","extern":"1","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B51.5"}],"quality_controlled":"1","oa_version":"Published Version","volume":65,"citation":{"ista":"Polshyn H, Zhu J, Kumar M, Taniguchi T, Watanabe K, MacDonald A, Young A. 2020. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B51.00005.","ama":"Polshyn H, Zhu J, Kumar M, et al. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Polshyn, H., Zhu, J., Kumar, M., Taniguchi, T., Watanabe, K., MacDonald, A., &#38; Young, A. (2020). Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Polshyn, Hryhoriy, et al. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B51.00005, American Physical Society, 2020.","ieee":"H. Polshyn <i>et al.</i>, “Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","short":"H. Polshyn, J. Zhu, M. Kumar, T. Taniguchi, K. Watanabe, A. MacDonald, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","chicago":"Polshyn, Hryhoriy, Jihang Zhu, Manish Kumar, Takashi Taniguchi, Kenji Watanabe, Allan MacDonald, and Andrea Young. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020."},"year":"2020","article_processing_charge":"No","publication_status":"published","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-03-01T00:00:00Z","article_number":"B51.00005","type":"conference","oa":1,"issue":"1","publication":"APS March Meeting 2020","month":"03","status":"public","alternative_title":["Bulletin of the American Physical Society"],"date_created":"2022-01-28T10:09:19Z","abstract":[{"text":"We experimentally investigate twisted van der Waals heterostructures of monolayer graphene rotated with respect to a bernal stacked graphene bilayer. We report transport measurements for devices with twist angles between 0.9 and 1.4°. The electric field allows efficient tuning of the width, isolation and the topology of the moiré bands in this system. By comparing magnetoresistance measurements to numerical simulations, we develop an understanding of the band structure. Finally, we observe correlated states at half- and quarter-fillings, which arise when narrow moire sublattice band is isolated by energy gaps from dispersive bands. We investigate the effects of in-plane and out-of-plane magnetic field on these states and discuss the implication for their spin- and valley- polarization.","lang":"eng"}],"publisher":"American Physical Society","language":[{"iso":"eng"}],"intvolume":"        65"},{"author":[{"first_name":"Yuxuan","last_name":"Zhang","full_name":"Zhang, Yuxuan"},{"first_name":"Marec","last_name":"Serlin","full_name":"Serlin, Marec"},{"first_name":"Charles","last_name":"Tschirhart","full_name":"Tschirhart, Charles"},{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","first_name":"Hryhoriy","last_name":"Polshyn","orcid":"0000-0001-8223-8896"},{"full_name":"Zhu, Jiacheng","last_name":"Zhu","first_name":"Jiacheng"},{"full_name":"Balents, Leon","last_name":"Balents","first_name":"Leon"},{"full_name":"Huber, Martin E.","last_name":"Huber","first_name":"Martin E."},{"first_name":"Takashi","last_name":"Taniguchi","full_name":"Taniguchi, Takashi"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"first_name":"Andrea","last_name":"Young","full_name":"Young, Andrea"}],"date_updated":"2023-02-21T15:57:52Z","title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport","related_material":{"record":[{"relation":"other","id":"10619","status":"public"}]},"acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work.","day":"01","arxiv":1,"conference":{"end_date":"2020-03-06","name":"APS: American Physical Society","location":"Denver, CO, United States","start_date":"2020-03-02"},"external_id":{"arxiv":["1907.00261"]},"extern":"1","_id":"10697","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.12"}],"oa_version":"Published Version","quality_controlled":"1","volume":65,"citation":{"chicago":"Zhang, Yuxuan, Marec Serlin, Charles Tschirhart, Hryhoriy Polshyn, Jiacheng Zhu, Leon Balents, Martin E. Huber, Takashi Taniguchi, Kenji Watanabe, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"Y. Zhang, M. Serlin, C. Tschirhart, H. Polshyn, J. Zhu, L. Balents, M.E. Huber, T. Taniguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","mla":"Zhang, Yuxuan, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00012, American Physical Society, 2020.","ieee":"Y. Zhang <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","ama":"Zhang Y, Serlin M, Tschirhart C, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Zhang Y, Serlin M, Tschirhart C, Polshyn H, Zhu J, Balents L, Huber ME, Taniguchi T, Watanabe K, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00012.","apa":"Zhang, Y., Serlin, M., Tschirhart, C., Polshyn, H., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society."},"year":"2020","article_processing_charge":"No","publication_status":"published","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-03-01T00:00:00Z","article_number":"B59.00012","type":"conference","oa":1,"issue":"1","month":"03","status":"public","publication":"APS March Meeting 2020","alternative_title":["Bulletin of the American Physical Society"],"date_created":"2022-01-28T10:28:35Z","abstract":[{"text":"We report the observation of a quantized anomalous Hall effect in a moiré heterostructure consisting of twisted bilayer graphene aligned to an encapsulating hBN substrate. The effect occurs at a density of 3 electrons per superlattice unit cell, where we observe magnetic hysteresis and a Hall resistance quantized to within 0.1% of the resistance quantum at temperatures as high as 3K. In this first of 3 talks, I will describe the fabrication procedure for our device as well as basic transport characterization measurements. I will introduce the phenomenology of twisted bilayer graphene and present evidence for hBN alignment as manifested in the hierarchy of symmetry-breaking gaps and anomalous magnetoresistance.","lang":"eng"}],"publisher":"American Physical Society","language":[{"iso":"eng"}],"intvolume":"        65"},{"year":"2020","article_processing_charge":"No","publication_status":"published","article_number":"B59.00011","date_published":"2020-03-01T00:00:00Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"type":"conference","issue":"1","month":"03","status":"public","publication":"APS March Meeting 2020","publisher":"American Physical Society","alternative_title":["Bulletin of the American Physical Society"],"date_created":"2022-01-28T10:46:57Z","abstract":[{"lang":"eng","text":"This is the second of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. I will compare the qualitative and quantitative features of this observed quantum anomalous Hall state to traditional systems engineered from thin film (Bi,Sb)2Te3 topological insulators. In particular, we find that the measured electronic energy gap of ~30K is several times higher than the Curie temperature, consistent with a lack of disorder associated with magnetic dopants. In this system, the quantization arises from spontaneous ferromagnetic polarization into a single spin and valley moiré subband, which is topological despite the lack of spin orbit coupling. I will also discuss the observation of current induced switching, which allows the magnetic state of the heterostructure to be controllably reversed with currents as small as a few nanoamperes."}],"intvolume":"        65","language":[{"iso":"eng"}],"author":[{"full_name":"Serlin, Marec","first_name":"Marec","last_name":"Serlin"},{"full_name":"Tschirhart, Charles","first_name":"Charles","last_name":"Tschirhart"},{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","last_name":"Polshyn","orcid":"0000-0001-8223-8896","first_name":"Hryhoriy"},{"full_name":"Zhang, Yuxuan","first_name":"Yuxuan","last_name":"Zhang"},{"full_name":"Zhu, Jiacheng","last_name":"Zhu","first_name":"Jiacheng"},{"full_name":"Huber, Martin E.","last_name":"Huber","first_name":"Martin E."},{"first_name":"Leon","last_name":"Balents","full_name":"Balents, Leon"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"last_name":"Tanaguchi","first_name":"Takashi","full_name":"Tanaguchi, Takashi"},{"full_name":"Young, Andrea","first_name":"Andrea","last_name":"Young"}],"date_updated":"2023-02-21T15:57:52Z","title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching","arxiv":1,"acknowledgement":"I would like to thank the MURI Program, AFOSR, Sloan Foundation, and the ARO for their generous support of this work.","related_material":{"record":[{"relation":"other","id":"10619","status":"public"}]},"day":"01","external_id":{"arxiv":["1907.00261"]},"conference":{"start_date":"2020-03-02","name":"APS: American Physical Society","location":"Denver, CO, United States","end_date":"2020-03-06"},"main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.11","open_access":"1"}],"quality_controlled":"1","oa_version":"Published Version","_id":"10698","extern":"1","volume":65,"citation":{"apa":"Serlin, M., Tschirhart, C., Polshyn, H., Zhang, Y., Zhu, J., Huber, M. E., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","ista":"Serlin M, Tschirhart C, Polshyn H, Zhang Y, Zhu J, Huber ME, Balents L, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00011.","ama":"Serlin M, Tschirhart C, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","mla":"Serlin, Marec, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00011, American Physical Society, 2020.","ieee":"M. Serlin <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","short":"M. Serlin, C. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, M.E. Huber, L. Balents, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","chicago":"Serlin, Marec, Charles Tschirhart, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Martin E. Huber, Leon Balents, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020."}},{"oa":1,"type":"conference","publication_status":"published","year":"2020","article_processing_charge":"No","date_published":"2020-03-01T00:00:00Z","article_number":"B59.00013","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publisher":"American Physical Society","date_created":"2022-01-28T10:57:49Z","abstract":[{"lang":"eng","text":"This is the third of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. In this segment I will present scanning probe magnetometry data acquired using a nanoSQUID-on-tip microscope, which provides ~150 nm spatial resolution and a field sensitivity of ~10 nT/rtHz. We study the distribution of magnetic domains within the device as a function of density, magnetic field training, and DC current. Our data allow us to constrain the magnitude of the orbital magnetic moment of the electrons in the QAH state. Comparison with simultaneously acquired transport data allows us to precisely correlate single domain dynamics with discrete jumps in the observed anomalous Hall signal."}],"alternative_title":["Bulletin of the American Physical Society"],"intvolume":"        65","language":[{"iso":"eng"}],"issue":"1","month":"03","status":"public","publication":"APS March Meeting 2020","arxiv":1,"day":"01","publication_identifier":{"issn":["0003-0503"]},"acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work. I would also like to thank the NSF GRFP and the Hertz foundation for their generous support of my graduate studies.","related_material":{"record":[{"status":"public","id":"10619","relation":"other"}]},"external_id":{"arxiv":["1907.00261"]},"conference":{"end_date":"2020-03-06","location":"Denver, CO, United States","name":"APS: American Physical Society","start_date":"2020-03-02"},"author":[{"full_name":"Tschirhart, Charles","last_name":"Tschirhart","first_name":"Charles"},{"full_name":"Serlin, Marec","first_name":"Marec","last_name":"Serlin"},{"last_name":"Polshyn","orcid":"0000-0001-8223-8896","first_name":"Hryhoriy","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"full_name":"Zhang, Yuxuan","last_name":"Zhang","first_name":"Yuxuan"},{"full_name":"Zhu, Jiacheng","first_name":"Jiacheng","last_name":"Zhu"},{"first_name":"Leon","last_name":"Balents","full_name":"Balents, Leon"},{"full_name":"Huber, Martin E.","last_name":"Huber","first_name":"Martin E."},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"last_name":"Tanaguchi","first_name":"Takashi","full_name":"Tanaguchi, Takashi"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry","date_updated":"2023-02-21T15:57:52Z","volume":65,"citation":{"short":"C. Tschirhart, M. Serlin, H. Polshyn, Y. Zhang, J. Zhu, L. Balents, M.E. Huber, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","chicago":"Tschirhart, Charles, Marec Serlin, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Leon Balents, Martin E. Huber, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","ama":"Tschirhart C, Serlin M, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Tschirhart C, Serlin M, Polshyn H, Zhang Y, Zhu J, Balents L, Huber ME, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00013.","apa":"Tschirhart, C., Serlin, M., Polshyn, H., Zhang, Y., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","mla":"Tschirhart, Charles, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00013, American Physical Society, 2020.","ieee":"C. Tschirhart <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1."},"quality_controlled":"1","oa_version":"Published Version","main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.13","open_access":"1"}],"extern":"1","_id":"10699"},{"_id":"10701","extern":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1904.11485"}],"oa_version":"Preprint","quality_controlled":"1","doi":"10.1038/s41567-019-0729-8","citation":{"ama":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. 2020;16(2):154-158. doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>","ista":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2020. Skyrmion solids in monolayer graphene. Nature Physics. 16(2), 154–158.","apa":"Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., &#38; Young, A. F. (2020). Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>","mla":"Zhou, Haoxin, et al. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>, vol. 16, no. 2, Springer Nature, 2020, pp. 154–58, doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>.","ieee":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Skyrmion solids in monolayer graphene,” <i>Nature Physics</i>, vol. 16, no. 2. Springer Nature, pp. 154–158, 2020.","short":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics 16 (2020) 154–158.","chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Taniguchi, Kenji Watanabe, and Andrea F. Young. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>."},"volume":16,"date_updated":"2022-01-31T07:10:07Z","title":"Skyrmion solids in monolayer graphene","author":[{"full_name":"Zhou, Haoxin","first_name":"Haoxin","last_name":"Zhou"},{"full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","last_name":"Polshyn","orcid":"0000-0001-8223-8896","first_name":"Hryhoriy"},{"first_name":"Takashi","last_name":"Taniguchi","full_name":"Taniguchi, Takashi"},{"full_name":"Watanabe, Kenji","last_name":"Watanabe","first_name":"Kenji"},{"full_name":"Young, Andrea F.","first_name":"Andrea F.","last_name":"Young"}],"external_id":{"arxiv":["1904.11485"]},"publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"article_type":"original","acknowledgement":"We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST (JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard Foundation and and Alfred. P. Sloan Foundation.","day":"01","arxiv":1,"publication":"Nature Physics","status":"public","month":"02","issue":"2","language":[{"iso":"eng"}],"intvolume":"        16","abstract":[{"text":"Partially filled Landau levels host competing electronic orders. For example, electron solids may prevail close to integer filling of the Landau levels before giving way to fractional quantum Hall liquids at higher carrier density1,2. Here, we report the observation of an electron solid with non-collinear spin texture in monolayer graphene, consistent with solidification of skyrmions3—topological spin textures characterized by quantized electrical charge4,5. We probe the spin texture of the solids using a modified Corbino geometry that allows ferromagnetic magnons to be launched and detected6,7. We find that magnon transport is highly efficient when one Landau level is filled (ν=1), consistent with quantum Hall ferromagnetic spin polarization. However, even minimal doping immediately quenches the magnon signal while leaving the vanishing low-temperature charge conductivity unchanged. Our results can be understood by the formation of a solid of charged skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay. Data near fractional fillings show evidence of several fractional skyrmion solids, suggesting that graphene hosts a highly tunable landscape of coupled spin and charge orders.","lang":"eng"}],"date_created":"2022-01-28T12:04:09Z","publisher":"Springer Nature","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","date_published":"2020-02-01T00:00:00Z","year":"2020","article_processing_charge":"No","publication_status":"published","type":"journal_article","oa":1,"page":"154-158"},{"department":[{"_id":"HeEd"}],"scopus_import":"1","volume":14,"project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships"}],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.1007/s11786-020-00461-5","citation":{"ama":"Choudhary A, Kachanovich S, Wintraecken M. Coxeter triangulations have good quality. <i>Mathematics in Computer Science</i>. 2020;14:141-176. doi:<a href=\"https://doi.org/10.1007/s11786-020-00461-5\">10.1007/s11786-020-00461-5</a>","apa":"Choudhary, A., Kachanovich, S., &#38; Wintraecken, M. (2020). Coxeter triangulations have good quality. <i>Mathematics in Computer Science</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11786-020-00461-5\">https://doi.org/10.1007/s11786-020-00461-5</a>","ista":"Choudhary A, Kachanovich S, Wintraecken M. 2020. Coxeter triangulations have good quality. Mathematics in Computer Science. 14, 141–176.","mla":"Choudhary, Aruni, et al. “Coxeter Triangulations Have Good Quality.” <i>Mathematics in Computer Science</i>, vol. 14, Springer Nature, 2020, pp. 141–76, doi:<a href=\"https://doi.org/10.1007/s11786-020-00461-5\">10.1007/s11786-020-00461-5</a>.","ieee":"A. Choudhary, S. Kachanovich, and M. Wintraecken, “Coxeter triangulations have good quality,” <i>Mathematics in Computer Science</i>, vol. 14. Springer Nature, pp. 141–176, 2020.","short":"A. Choudhary, S. Kachanovich, M. Wintraecken, Mathematics in Computer Science 14 (2020) 141–176.","chicago":"Choudhary, Aruni, Siargey Kachanovich, and Mathijs Wintraecken. “Coxeter Triangulations Have Good Quality.” <i>Mathematics in Computer Science</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s11786-020-00461-5\">https://doi.org/10.1007/s11786-020-00461-5</a>."},"_id":"7567","oa_version":"Published Version","quality_controlled":"1","publication_identifier":{"issn":["1661-8270"],"eissn":["1661-8289"]},"article_type":"original","file_date_updated":"2020-11-20T10:18:02Z","day":"01","author":[{"first_name":"Aruni","last_name":"Choudhary","full_name":"Choudhary, Aruni"},{"full_name":"Kachanovich, Siargey","last_name":"Kachanovich","first_name":"Siargey"},{"first_name":"Mathijs","last_name":"Wintraecken","orcid":"0000-0002-7472-2220","full_name":"Wintraecken, Mathijs","id":"307CFBC8-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2025-04-14T07:44:03Z","title":"Coxeter triangulations have good quality","date_created":"2020-03-05T13:30:18Z","abstract":[{"text":"Coxeter triangulations are triangulations of Euclidean space based on a single simplex. By this we mean that given an individual simplex we can recover the entire triangulation of Euclidean space by inductively reflecting in the faces of the simplex. In this paper we establish that the quality of the simplices in all Coxeter triangulations is O(1/d−−√) of the quality of regular simplex. We further investigate the Delaunay property for these triangulations. Moreover, we consider an extension of the Delaunay property, namely protection, which is a measure of non-degeneracy of a Delaunay triangulation. In particular, one family of Coxeter triangulations achieves the protection O(1/d2). We conjecture that both bounds are optimal for triangulations in Euclidean space.","lang":"eng"}],"has_accepted_license":"1","publisher":"Springer Nature","language":[{"iso":"eng"}],"intvolume":"        14","ddc":["510"],"publication":"Mathematics in Computer Science","corr_author":"1","month":"03","status":"public","page":"141-176","ec_funded":1,"type":"journal_article","oa":1,"article_processing_charge":"Yes (via OA deal)","year":"2020","publication_status":"published","file":[{"date_updated":"2020-11-20T10:18:02Z","success":1,"file_id":"8783","content_type":"application/pdf","access_level":"open_access","file_size":872275,"creator":"dernst","file_name":"2020_MathCompScie_Choudhary.pdf","checksum":"1d145f3ab50ccee735983cb89236e609","relation":"main_file","date_created":"2020-11-20T10:18:02Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2020-03-01T00:00:00Z"},{"file":[{"file_name":"2020_PlosCompBio_Grah.pdf","creator":"dernst","checksum":"5239dd134dc6e1c71fe7b3ce2953da37","relation":"main_file","date_created":"2020-03-09T15:12:21Z","content_type":"application/pdf","access_level":"open_access","file_size":2209325,"file_id":"7579","date_updated":"2020-07-14T12:48:00Z"}],"publication_status":"published","year":"2020","article_processing_charge":"No","article_number":"e1007642","date_published":"2020-02-25T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"type":"journal_article","isi":1,"issue":"2","month":"02","ddc":["000","570"],"publication":"PLOS Computational Biology","status":"public","publisher":"Public Library of Science","has_accepted_license":"1","date_created":"2020-03-06T07:39:38Z","pmid":1,"abstract":[{"lang":"eng","text":"Genes differ in the frequency at which they are expressed and in the form of regulation used to control their activity. In particular, positive or negative regulation can lead to activation of a gene in response to an external signal. Previous works proposed that the form of regulation of a gene correlates with its frequency of usage: positive regulation when the gene is frequently expressed and negative regulation when infrequently expressed. Such network design means that, in the absence of their regulators, the genes are found in their least required activity state, hence regulatory intervention is often necessary. Due to the multitude of genes and regulators, spurious binding and unbinding events, called “crosstalk”, could occur. To determine how the form of regulation affects the global crosstalk in the network, we used a mathematical model that includes multiple regulators and multiple target genes. We found that crosstalk depends non-monotonically on the availability of regulators. Our analysis showed that excess use of regulation entailed by the formerly suggested network design caused high crosstalk levels in a large part of the parameter space. We therefore considered the opposite ‘idle’ design, where the default unregulated state of genes is their frequently required activity state. We found, that ‘idle’ design minimized the use of regulation and thus minimized crosstalk. In addition, we estimated global crosstalk of S. cerevisiae using transcription factors binding data. We demonstrated that even partial network data could suffice to estimate its global crosstalk, suggesting its applicability to additional organisms. We found that S. cerevisiae estimated crosstalk is lower than that of a random network, suggesting that natural selection reduces crosstalk. In summary, our study highlights a new type of protein production cost which is typically overlooked: that of regulatory interference caused by the presence of excess regulators in the cell. It demonstrates the importance of whole-network descriptions, which could show effects missed by single-gene models."}],"intvolume":"        16","language":[{"iso":"eng"}],"author":[{"last_name":"Grah","orcid":"0000-0003-2539-3560","first_name":"Rok","full_name":"Grah, Rok","id":"483E70DE-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Tamar","last_name":"Friedlander","full_name":"Friedlander, Tamar"}],"title":"The relation between crosstalk and gene regulation form revisited","date_updated":"2026-04-08T07:25:08Z","day":"25","related_material":{"record":[{"relation":"research_data","id":"9716","status":"deleted"},{"relation":"research_data","id":"9776","status":"public"},{"status":"public","id":"9779","relation":"research_data"},{"id":"9777","relation":"research_data","status":"public"},{"status":"public","id":"8155","relation":"dissertation_contains"}]},"file_date_updated":"2020-07-14T12:48:00Z","article_type":"original","publication_identifier":{"issn":["1553-7358"]},"external_id":{"pmid":["32097416"],"isi":["000526725200019"]},"oa_version":"Published Version","quality_controlled":"1","_id":"7569","volume":16,"scopus_import":"1","department":[{"_id":"CaGu"},{"_id":"GaTk"}],"doi":"10.1371/journal.pcbi.1007642","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"mla":"Grah, Rok, and Tamar Friedlander. “The Relation between Crosstalk and Gene Regulation Form Revisited.” <i>PLOS Computational Biology</i>, vol. 16, no. 2, e1007642, Public Library of Science, 2020, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">10.1371/journal.pcbi.1007642</a>.","ieee":"R. Grah and T. Friedlander, “The relation between crosstalk and gene regulation form revisited,” <i>PLOS Computational Biology</i>, vol. 16, no. 2. Public Library of Science, 2020.","apa":"Grah, R., &#38; Friedlander, T. (2020). The relation between crosstalk and gene regulation form revisited. <i>PLOS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">https://doi.org/10.1371/journal.pcbi.1007642</a>","ama":"Grah R, Friedlander T. The relation between crosstalk and gene regulation form revisited. <i>PLOS Computational Biology</i>. 2020;16(2). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">10.1371/journal.pcbi.1007642</a>","ista":"Grah R, Friedlander T. 2020. The relation between crosstalk and gene regulation form revisited. PLOS Computational Biology. 16(2), e1007642.","chicago":"Grah, Rok, and Tamar Friedlander. “The Relation between Crosstalk and Gene Regulation Form Revisited.” <i>PLOS Computational Biology</i>. Public Library of Science, 2020. <a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">https://doi.org/10.1371/journal.pcbi.1007642</a>.","short":"R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020)."}},{"author":[{"full_name":"Michailidis, Alexios","id":"36EBAD38-F248-11E8-B48F-1D18A9856A87","last_name":"Michailidis","orcid":"0000-0002-8443-1064","first_name":"Alexios"},{"first_name":"C. J.","last_name":"Turner","full_name":"Turner, C. J."},{"first_name":"Z.","last_name":"Papić","full_name":"Papić, Z."},{"first_name":"D. A.","last_name":"Abanin","full_name":"Abanin, D. A."},{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","first_name":"Maksym","orcid":"0000-0002-2399-5827","last_name":"Serbyn"}],"date_updated":"2023-08-18T07:01:07Z","title":"Slow quantum thermalization and many-body revivals from mixed phase space","arxiv":1,"file_date_updated":"2020-07-14T12:48:00Z","article_type":"original","publication_identifier":{"issn":["2160-3308"]},"related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/classical-physics-helps-predict-fate-of-interacting-quantum-systems/","description":"News on IST Homepage"}]},"day":"04","external_id":{"isi":["000517969300001"],"arxiv":["1905.08564"]},"quality_controlled":"1","oa_version":"Published Version","_id":"7570","volume":10,"department":[{"_id":"MaSe"}],"scopus_import":"1","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"doi":"10.1103/physrevx.10.011055","citation":{"ista":"Michailidis A, Turner CJ, Papić Z, Abanin DA, Serbyn M. 2020. Slow quantum thermalization and many-body revivals from mixed phase space. Physical Review X. 10(1), 011055.","apa":"Michailidis, A., Turner, C. J., Papić, Z., Abanin, D. A., &#38; Serbyn, M. (2020). Slow quantum thermalization and many-body revivals from mixed phase space. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevx.10.011055\">https://doi.org/10.1103/physrevx.10.011055</a>","ama":"Michailidis A, Turner CJ, Papić Z, Abanin DA, Serbyn M. Slow quantum thermalization and many-body revivals from mixed phase space. <i>Physical Review X</i>. 2020;10(1). doi:<a href=\"https://doi.org/10.1103/physrevx.10.011055\">10.1103/physrevx.10.011055</a>","ieee":"A. Michailidis, C. J. Turner, Z. Papić, D. A. Abanin, and M. Serbyn, “Slow quantum thermalization and many-body revivals from mixed phase space,” <i>Physical Review X</i>, vol. 10, no. 1. American Physical Society, 2020.","mla":"Michailidis, Alexios, et al. “Slow Quantum Thermalization and Many-Body Revivals from Mixed Phase Space.” <i>Physical Review X</i>, vol. 10, no. 1, 011055, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/physrevx.10.011055\">10.1103/physrevx.10.011055</a>.","short":"A. Michailidis, C.J. Turner, Z. Papić, D.A. Abanin, M. Serbyn, Physical Review X 10 (2020).","chicago":"Michailidis, Alexios, C. J. Turner, Z. Papić, D. A. Abanin, and Maksym Serbyn. “Slow Quantum Thermalization and Many-Body Revivals from Mixed Phase Space.” <i>Physical Review X</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/physrevx.10.011055\">https://doi.org/10.1103/physrevx.10.011055</a>."},"file":[{"file_id":"7581","date_updated":"2020-07-14T12:48:00Z","creator":"dernst","checksum":"4b3f2c13873d35230173c73d0e11c408","file_name":"2020_PhysicalReviewX_Michailidis.pdf","relation":"main_file","date_created":"2020-03-12T12:13:07Z","content_type":"application/pdf","access_level":"open_access","file_size":17828638}],"year":"2020","article_processing_charge":"No","publication_status":"published","date_published":"2020-03-04T00:00:00Z","article_number":"011055","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa":1,"isi":1,"type":"journal_article","issue":"1","publication":"Physical Review X","status":"public","month":"03","ddc":["530"],"publisher":"American Physical Society","abstract":[{"text":"The relaxation of few-body quantum systems can strongly depend on the initial state when the system’s semiclassical phase space is mixed; i.e., regions of chaotic motion coexist with regular islands. In recent years, there has been much effort to understand the process of thermalization in strongly interacting quantum systems that often lack an obvious semiclassical limit. The time-dependent variational principle (TDVP) allows one to systematically derive an effective classical (nonlinear) dynamical system by projecting unitary many-body dynamics onto a manifold of weakly entangled variational states. We demonstrate that such dynamical systems generally possess mixed phase space. When TDVP errors are small, the mixed phase space leaves a footprint on the exact dynamics of the quantum model. For example, when the system is initialized in a state belonging to a stable periodic orbit or the surrounding regular region, it exhibits persistent many-body quantum revivals. As a proof of principle, we identify new types of “quantum many-body scars,” i.e., initial states that lead to long-time oscillations in a model of interacting Rydberg atoms in one and two dimensions. Intriguingly, the initial states that give rise to most robust revivals are typically entangled states. On the other hand, even when TDVP errors are large, as in the thermalizing tilted-field Ising model, initializing the system in a regular region of phase space leads to a surprising slowdown of thermalization. Our work establishes TDVP as a method for identifying interacting quantum systems with anomalous dynamics in arbitrary dimensions. Moreover, the mixed phase space classical variational equations allow one to find slowly thermalizing initial conditions in interacting models. Our results shed light on a link between classical and quantum chaos, pointing toward possible extensions of the classical Kolmogorov-Arnold-Moser theorem to quantum systems.","lang":"eng"}],"date_created":"2020-03-08T18:02:01Z","has_accepted_license":"1","intvolume":"        10","language":[{"iso":"eng"}]},{"editor":[{"last_name":"Tran","first_name":"Phong ","full_name":"Tran, Phong "}],"page":"145-161","ec_funded":1,"isi":1,"type":"book_chapter","oa":1,"publication_status":"published","year":"2020","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2020-02-27T00:00:00Z","abstract":[{"text":"The polymerization–depolymerization dynamics of cytoskeletal proteins play essential roles in the self-organization of cytoskeletal structures, in eukaryotic as well as prokaryotic cells. While advances in fluorescence microscopy and in vitro reconstitution experiments have helped to study the dynamic properties of these complex systems, methods that allow to collect and analyze large quantitative datasets of the underlying polymer dynamics are still missing. Here, we present a novel image analysis workflow to study polymerization dynamics of active filaments in a nonbiased, highly automated manner. Using treadmilling filaments of the bacterial tubulin FtsZ as an example, we demonstrate that our method is able to specifically detect, track and analyze growth and shrinkage of polymers, even in dense networks of filaments. We believe that this automated method can facilitate the analysis of a large variety of dynamic cytoskeletal systems, using standard time-lapse movies obtained from experiments in vitro as well as in the living cell. Moreover, we provide scripts implementing this method as supplementary material.","lang":"eng"}],"date_created":"2020-03-08T23:00:47Z","alternative_title":["Methods in Cell Biology"],"publisher":"Elsevier","language":[{"iso":"eng"}],"intvolume":"       158","publication":"Methods in Cell Biology","status":"public","month":"02","day":"27","related_material":{"record":[{"status":"public","id":"8358","relation":"part_of_dissertation"}]},"publication_identifier":{"issn":["0091-679X"]},"external_id":{"isi":["000611826500008"]},"author":[{"orcid":"0000-0001-6730-4461","last_name":"Dos Santos Caldas","first_name":"Paulo R","id":"38FCDB4C-F248-11E8-B48F-1D18A9856A87","full_name":"Dos Santos Caldas, Paulo R"},{"id":"40136C2A-F248-11E8-B48F-1D18A9856A87","full_name":"Radler, Philipp","first_name":"Philipp","orcid":"0000-0001-9198-2182 ","last_name":"Radler"},{"orcid":"0000-0003-1216-9105","last_name":"Sommer","first_name":"Christoph M","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","full_name":"Sommer, Christoph M"},{"full_name":"Loose, Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87","first_name":"Martin","last_name":"Loose","orcid":"0000-0001-7309-9724"}],"title":"Computational analysis of filament polymerization dynamics in cytoskeletal networks","date_updated":"2026-04-08T07:26:30Z","department":[{"_id":"MaLo"}],"scopus_import":"1","volume":158,"project":[{"grant_number":"679239","name":"Self-Organization of the Bacterial Cell","_id":"2595697A-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"name":"Reconstitution of Bacterial Cell Division Using Purified Components","_id":"260D98C8-B435-11E9-9278-68D0E5697425"}],"citation":{"chicago":"Dos Santos Caldas, Paulo R, Philipp Radler, Christoph M Sommer, and Martin Loose. “Computational Analysis of Filament Polymerization Dynamics in Cytoskeletal Networks.” In <i>Methods in Cell Biology</i>, edited by Phong  Tran, 158:145–61. Elsevier, 2020. <a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">https://doi.org/10.1016/bs.mcb.2020.01.006</a>.","short":"P.R. Dos Santos Caldas, P. Radler, C.M. Sommer, M. Loose, in:, P. Tran (Ed.), Methods in Cell Biology, Elsevier, 2020, pp. 145–161.","mla":"Dos Santos Caldas, Paulo R., et al. “Computational Analysis of Filament Polymerization Dynamics in Cytoskeletal Networks.” <i>Methods in Cell Biology</i>, edited by Phong  Tran, vol. 158, Elsevier, 2020, pp. 145–61, doi:<a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">10.1016/bs.mcb.2020.01.006</a>.","ieee":"P. R. Dos Santos Caldas, P. Radler, C. M. Sommer, and M. Loose, “Computational analysis of filament polymerization dynamics in cytoskeletal networks,” in <i>Methods in Cell Biology</i>, vol. 158, P. Tran, Ed. Elsevier, 2020, pp. 145–161.","ama":"Dos Santos Caldas PR, Radler P, Sommer CM, Loose M. Computational analysis of filament polymerization dynamics in cytoskeletal networks. In: Tran P, ed. <i>Methods in Cell Biology</i>. Vol 158. Elsevier; 2020:145-161. doi:<a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">10.1016/bs.mcb.2020.01.006</a>","ista":"Dos Santos Caldas PR, Radler P, Sommer CM, Loose M. 2020.Computational analysis of filament polymerization dynamics in cytoskeletal networks. In: Methods in Cell Biology. Methods in Cell Biology, vol. 158, 145–161.","apa":"Dos Santos Caldas, P. R., Radler, P., Sommer, C. M., &#38; Loose, M. (2020). Computational analysis of filament polymerization dynamics in cytoskeletal networks. In P. Tran (Ed.), <i>Methods in Cell Biology</i> (Vol. 158, pp. 145–161). Elsevier. <a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">https://doi.org/10.1016/bs.mcb.2020.01.006</a>"},"doi":"10.1016/bs.mcb.2020.01.006","_id":"7572","oa_version":"Preprint","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/839571"}]},{"volume":139,"department":[{"_id":"JaMa"}],"scopus_import":"1","doi":"10.1016/j.matpur.2020.02.008","citation":{"chicago":"Gladbach, Peter, Eva Kopfer, Jan Maas, and Lorenzo Portinale. “Homogenisation of One-Dimensional Discrete Optimal Transport.” <i>Journal de Mathematiques Pures et Appliquees</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">https://doi.org/10.1016/j.matpur.2020.02.008</a>.","short":"P. Gladbach, E. Kopfer, J. Maas, L. Portinale, Journal de Mathematiques Pures et Appliquees 139 (2020) 204–234.","ieee":"P. Gladbach, E. Kopfer, J. Maas, and L. Portinale, “Homogenisation of one-dimensional discrete optimal transport,” <i>Journal de Mathematiques Pures et Appliquees</i>, vol. 139, no. 7. Elsevier, pp. 204–234, 2020.","mla":"Gladbach, Peter, et al. “Homogenisation of One-Dimensional Discrete Optimal Transport.” <i>Journal de Mathematiques Pures et Appliquees</i>, vol. 139, no. 7, Elsevier, 2020, pp. 204–34, doi:<a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">10.1016/j.matpur.2020.02.008</a>.","ama":"Gladbach P, Kopfer E, Maas J, Portinale L. Homogenisation of one-dimensional discrete optimal transport. <i>Journal de Mathematiques Pures et Appliquees</i>. 2020;139(7):204-234. doi:<a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">10.1016/j.matpur.2020.02.008</a>","ista":"Gladbach P, Kopfer E, Maas J, Portinale L. 2020. Homogenisation of one-dimensional discrete optimal transport. Journal de Mathematiques Pures et Appliquees. 139(7), 204–234.","apa":"Gladbach, P., Kopfer, E., Maas, J., &#38; Portinale, L. (2020). Homogenisation of one-dimensional discrete optimal transport. <i>Journal de Mathematiques Pures et Appliquees</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">https://doi.org/10.1016/j.matpur.2020.02.008</a>"},"project":[{"_id":"256E75B8-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"716117","name":"Optimal Transport and Stochastic Dynamics"},{"grant_number":"F06504","name":"Taming Complexity in Partial Differential Systems","_id":"260482E2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"_id":"260788DE-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"W1245","name":"Dissipation and dispersion in nonlinear partial differential equations"}],"main_file_link":[{"url":"https://arxiv.org/abs/1905.05757","open_access":"1"}],"oa_version":"Preprint","quality_controlled":"1","_id":"7573","arxiv":1,"publication_identifier":{"issn":["0021-7824"]},"article_type":"original","acknowledgement":"J.M. gratefully acknowledges support by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No 716117). J.M. and L.P. also acknowledge support from the Austrian Science Fund (FWF), grants No F65 and W1245. E.K. gratefully acknowledges support by the German Research Foundation through the Hausdorff Center for Mathematics and the Collaborative Research Center 1060. P.G. is partially funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 350398276.","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"10030"}]},"day":"01","external_id":{"isi":["000539439400008"],"arxiv":["1905.05757"]},"author":[{"full_name":"Gladbach, Peter","last_name":"Gladbach","first_name":"Peter"},{"full_name":"Kopfer, Eva","first_name":"Eva","last_name":"Kopfer"},{"orcid":"0000-0002-0845-1338","last_name":"Maas","first_name":"Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan"},{"last_name":"Portinale","first_name":"Lorenzo","full_name":"Portinale, Lorenzo","id":"30AD2CBC-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2026-04-08T07:00:03Z","title":"Homogenisation of one-dimensional discrete optimal transport","publisher":"Elsevier","abstract":[{"lang":"eng","text":"This paper deals with dynamical optimal transport metrics defined by spatial discretisation of the Benamou–Benamou formula for the Kantorovich metric . Such metrics appear naturally in discretisations of -gradient flow formulations for dissipative PDE. However, it has recently been shown that these metrics do not in general converge to , unless strong geometric constraints are imposed on the discrete mesh. In this paper we prove that, in a 1-dimensional periodic setting, discrete transport metrics converge to a limiting transport metric with a non-trivial effective mobility. This mobility depends sensitively on the geometry of the mesh and on the non-local mobility at the discrete level. Our result quantifies to what extent discrete transport can make use of microstructure in the mesh to reduce the cost of transport."}],"date_created":"2020-03-08T23:00:47Z","intvolume":"       139","language":[{"iso":"eng"}],"issue":"7","status":"public","month":"07","publication":"Journal de Mathematiques Pures et Appliquees","page":"204-234","oa":1,"isi":1,"ec_funded":1,"type":"journal_article","year":"2020","article_processing_charge":"No","publication_status":"published","date_published":"2020-07-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"department":[{"_id":"MaLo"},{"_id":"CaBe"}],"scopus_import":"1","volume":117,"project":[{"name":"Reconstitution of cell polarity and axis determination in a cell-free system","grant_number":"RGY0083/2016","_id":"2599F062-B435-11E9-9278-68D0E5697425"}],"citation":{"chicago":"Bezeljak, Urban, Hrushikesh Loya, Beata M Kaczmarek, Timothy E. Saunders, and Martin Loose. “Stochastic Activation and Bistability in a Rab GTPase Regulatory Network.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2020. <a href=\"https://doi.org/10.1073/pnas.1921027117\">https://doi.org/10.1073/pnas.1921027117</a>.","short":"U. Bezeljak, H. Loya, B.M. Kaczmarek, T.E. Saunders, M. Loose, Proceedings of the National Academy of Sciences of the United States of America 117 (2020) 6504–6549.","ieee":"U. Bezeljak, H. Loya, B. M. Kaczmarek, T. E. Saunders, and M. Loose, “Stochastic activation and bistability in a Rab GTPase regulatory network,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 117, no. 12. National Academy of Sciences, pp. 6504–6549, 2020.","mla":"Bezeljak, Urban, et al. “Stochastic Activation and Bistability in a Rab GTPase Regulatory Network.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 117, no. 12, National Academy of Sciences, 2020, pp. 6504–49, doi:<a href=\"https://doi.org/10.1073/pnas.1921027117\">10.1073/pnas.1921027117</a>.","ama":"Bezeljak U, Loya H, Kaczmarek BM, Saunders TE, Loose M. Stochastic activation and bistability in a Rab GTPase regulatory network. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2020;117(12):6504-6549. doi:<a href=\"https://doi.org/10.1073/pnas.1921027117\">10.1073/pnas.1921027117</a>","ista":"Bezeljak U, Loya H, Kaczmarek BM, Saunders TE, Loose M. 2020. Stochastic activation and bistability in a Rab GTPase regulatory network. Proceedings of the National Academy of Sciences of the United States of America. 117(12), 6504–6549.","apa":"Bezeljak, U., Loya, H., Kaczmarek, B. M., Saunders, T. E., &#38; Loose, M. (2020). Stochastic activation and bistability in a Rab GTPase regulatory network. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1921027117\">https://doi.org/10.1073/pnas.1921027117</a>"},"doi":"10.1073/pnas.1921027117","_id":"7580","quality_controlled":"1","oa_version":"Preprint","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/776567"}],"day":"24","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"related_material":{"link":[{"url":"https://ist.ac.at/en/news/proteins-as-molecular-switches/","relation":"press_release","description":"News on IST Homepage"}],"record":[{"status":"public","id":"8341","relation":"dissertation_contains"}]},"article_type":"original","external_id":{"isi":["000521821800040"],"pmid":["32161136"]},"author":[{"last_name":"Bezeljak","orcid":"0000-0003-1365-5631","first_name":"Urban","full_name":"Bezeljak, Urban","id":"2A58201A-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Loya, Hrushikesh","first_name":"Hrushikesh","last_name":"Loya"},{"id":"36FA4AFA-F248-11E8-B48F-1D18A9856A87","full_name":"Kaczmarek, Beata M","first_name":"Beata M","last_name":"Kaczmarek"},{"last_name":"Saunders","first_name":"Timothy E.","full_name":"Saunders, Timothy E."},{"last_name":"Loose","orcid":"0000-0001-7309-9724","first_name":"Martin","full_name":"Loose, Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87"}],"title":"Stochastic activation and bistability in a Rab GTPase regulatory network","date_updated":"2026-04-08T07:24:55Z","date_created":"2020-03-12T05:32:26Z","abstract":[{"text":"The eukaryotic endomembrane system is controlled by small GTPases of the Rab family, which are activated at defined times and locations in a switch-like manner. While this switch is well understood for an individual protein, how regulatory networks produce intracellular activity patterns is currently not known. Here, we combine in vitro reconstitution experiments with computational modeling to study a minimal Rab5 activation network. We find that the molecular interactions in this system give rise to a positive feedback and bistable collective switching of Rab5. Furthermore, we find that switching near the critical point is intrinsically stochastic and provide evidence that controlling the inactive population of Rab5 on the membrane can shape the network response. Notably, we demonstrate that collective switching can spread on the membrane surface as a traveling wave of Rab5 activation. Together, our findings reveal how biochemical signaling networks control vesicle trafficking pathways and how their nonequilibrium properties define the spatiotemporal organization of the cell.","lang":"eng"}],"pmid":1,"publisher":"National Academy of Sciences","language":[{"iso":"eng"}],"intvolume":"       117","issue":"12","month":"03","status":"public","publication":"Proceedings of the National Academy of Sciences of the United States of America","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"page":"6504-6549","isi":1,"type":"journal_article","oa":1,"publication_status":"published","year":"2020","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2020-03-24T00:00:00Z"},{"file":[{"date_updated":"2020-07-14T12:48:00Z","file_id":"7614","file_size":2373484,"access_level":"open_access","content_type":"application/pdf","date_created":"2020-03-23T13:37:00Z","relation":"main_file","checksum":"6d5af3e17266a48996b4af4e67e88a85","creator":"dernst","file_name":"2020_Plants_Moturu.pdf"}],"year":"2020","article_processing_charge":"No","publication_status":"published","article_number":"299","date_published":"2020-03-01T00:00:00Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"ec_funded":1,"type":"journal_article","isi":1,"issue":"3","month":"03","ddc":["580"],"corr_author":"1","status":"public","publication":"Plants","publisher":"MDPI","has_accepted_license":"1","pmid":1,"date_created":"2020-03-15T23:00:52Z","abstract":[{"text":"Small RNAs (smRNA, 19–25 nucleotides long), which are transcribed by RNA polymerase II, regulate the expression of genes involved in a multitude of processes in eukaryotes. miRNA biogenesis and the proteins involved in the biogenesis pathway differ across plant and animal lineages. The major proteins constituting the biogenesis pathway, namely, the Dicers (DCL/DCR) and Argonautes (AGOs), have been extensively studied. However, the accessory proteins (DAWDLE (DDL), SERRATE (SE), and TOUGH (TGH)) of the pathway that differs across the two lineages remain largely uncharacterized. We present the first detailed report on the molecular evolution and divergence of these proteins across eukaryotes. Although DDL is present in eukaryotes and prokaryotes, SE and TGH appear to be specific to eukaryotes. The addition/deletion of specific domains and/or domain-specific sequence divergence in the three proteins points to the observed functional divergence of these proteins across the two lineages, which correlates with the differences in miRNA length across the two lineages. Our data enhance the current understanding of the structure–function relationship of these proteins and reveals previous unexplored crucial residues in the three proteins that can be used as a basis for further functional characterization. The data presented here on the number of miRNAs in crown eukaryotic lineages are consistent with the notion of the expansion of the number of miRNA-coding genes in animal and plant lineages correlating with organismal complexity. Whether this difference in functionally correlates with the diversification (or presence/absence) of the three proteins studied here or the miRNA signaling in the plant and animal lineages is unclear. Based on our results of the three proteins studied here and previously available data concerning the evolution of miRNA genes in the plant and animal lineages, we believe that miRNAs probably evolved once in the ancestor to crown eukaryotes and have diversified independently in the eukaryotes.","lang":"eng"}],"intvolume":"         9","language":[{"iso":"eng"}],"author":[{"first_name":"Taraka Ramji","last_name":"Moturu","full_name":"Moturu, Taraka Ramji"},{"full_name":"Sinha, Sansrity","last_name":"Sinha","first_name":"Sansrity"},{"full_name":"Salava, Hymavathi","first_name":"Hymavathi","last_name":"Salava"},{"last_name":"Thula","first_name":"Sravankumar","full_name":"Thula, Sravankumar"},{"full_name":"Nodzyński, Tomasz","last_name":"Nodzyński","first_name":"Tomasz"},{"last_name":"Vařeková","first_name":"Radka Svobodová","full_name":"Vařeková, Radka Svobodová"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","first_name":"Jiří","orcid":"0000-0002-8302-7596","last_name":"Friml"},{"first_name":"Sibu","last_name":"Simon","orcid":"0000-0002-1998-6741","full_name":"Simon, Sibu","id":"4542EF9A-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2026-04-02T14:35:47Z","title":"Molecular evolution and diversification of proteins involved in miRNA maturation pathway","file_date_updated":"2020-07-14T12:48:00Z","article_type":"original","publication_identifier":{"eissn":["2223-7747"]},"day":"01","external_id":{"isi":["000525315000035"],"pmid":["32121542"]},"quality_controlled":"1","oa_version":"Published Version","_id":"7582","volume":9,"department":[{"_id":"JiFr"}],"scopus_import":"1","doi":"10.3390/plants9030299","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"citation":{"ista":"Moturu TR, Sinha S, Salava H, Thula S, Nodzyński T, Vařeková RS, Friml J, Simon S. 2020. Molecular evolution and diversification of proteins involved in miRNA maturation pathway. Plants. 9(3), 299.","ama":"Moturu TR, Sinha S, Salava H, et al. Molecular evolution and diversification of proteins involved in miRNA maturation pathway. <i>Plants</i>. 2020;9(3). doi:<a href=\"https://doi.org/10.3390/plants9030299\">10.3390/plants9030299</a>","apa":"Moturu, T. R., Sinha, S., Salava, H., Thula, S., Nodzyński, T., Vařeková, R. S., … Simon, S. (2020). Molecular evolution and diversification of proteins involved in miRNA maturation pathway. <i>Plants</i>. MDPI. <a href=\"https://doi.org/10.3390/plants9030299\">https://doi.org/10.3390/plants9030299</a>","ieee":"T. R. Moturu <i>et al.</i>, “Molecular evolution and diversification of proteins involved in miRNA maturation pathway,” <i>Plants</i>, vol. 9, no. 3. MDPI, 2020.","mla":"Moturu, Taraka Ramji, et al. “Molecular Evolution and Diversification of Proteins Involved in MiRNA Maturation Pathway.” <i>Plants</i>, vol. 9, no. 3, 299, MDPI, 2020, doi:<a href=\"https://doi.org/10.3390/plants9030299\">10.3390/plants9030299</a>.","short":"T.R. Moturu, S. Sinha, H. Salava, S. Thula, T. Nodzyński, R.S. Vařeková, J. Friml, S. Simon, Plants 9 (2020).","chicago":"Moturu, Taraka Ramji, Sansrity Sinha, Hymavathi Salava, Sravankumar Thula, Tomasz Nodzyński, Radka Svobodová Vařeková, Jiří Friml, and Sibu Simon. “Molecular Evolution and Diversification of Proteins Involved in MiRNA Maturation Pathway.” <i>Plants</i>. MDPI, 2020. <a href=\"https://doi.org/10.3390/plants9030299\">https://doi.org/10.3390/plants9030299</a>."},"project":[{"grant_number":"282300","name":"Polarity and subcellular dynamics in plants","_id":"25716A02-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"}]}]