[{"author":[{"first_name":"Haoxin","last_name":"Zhou","full_name":"Zhou, Haoxin"},{"id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy","last_name":"Polshyn","first_name":"Hryhoriy","orcid":"0000-0001-8223-8896"},{"full_name":"Tanaguchi, Takashi","last_name":"Tanaguchi","first_name":"Takashi"},{"full_name":"Watanabe, Kenji","last_name":"Watanabe","first_name":"Kenji"},{"first_name":"Andrea","last_name":"Young","full_name":"Young, Andrea"}],"alternative_title":["Bulletin of the American Physical Society"],"publication_status":"published","year":"2020","month":"03","issue":"1","volume":65,"abstract":[{"text":"High quality graphene heterostructures host an array of fractional quantum Hall isospin ferromagnets with diverse spin and valley orders. While a variety of phase transitions have been observed, disentangling the isospin phase diagram of these states is hampered by the absence of direct probes of spin and valley order. I will describe nonlocal transport measurements based on launching spin waves from a gate defined lateral heterojunction, performed in ultra-clean Corbino geometry graphene devices. At high magnetic fields, we find that the spin-wave transport signal is detected in all FQH states between ν = 0 and 1; however, between ν = 1 and 2 only odd numerator FQH states show finite nonlocal transport, despite the identical ground state spin polarizations in odd- and even numerator states. The results reveal that the neutral spin-waves are both spin and sublattice polarized making them a sensitive probe of ground state sublattice structure. Armed with this understanding, we use nonlocal transport signal to a magnetic field tuned isospin phase transition, showing that the emergent even denominator state at ν = 1/2 in monolayer graphene is indeed a multicomponent state featuring equal populations on each sublattice.","lang":"eng"}],"status":"public","publication":"APS March Meeting 2020","oa_version":"Published Version","date_created":"2022-01-27T10:50:10Z","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B54.7"}],"type":"conference","citation":{"chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Tanaguchi, Kenji Watanabe, and Andrea Young. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","mla":"Zhou, Haoxin, et al. “Sublattice Resolved Spin Wave Transport through Graphene Fractional Quantum Hall States as a Probe of Isospin Order.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B54. 00007, American Physical Society, 2020.","short":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","apa":"Zhou, H., Polshyn, H., Tanaguchi, T., Watanabe, K., &#38; Young, A. (2020). Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","ista":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. 2020. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B54. 00007.","ama":"Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ieee":"H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, and A. Young, “Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1."},"language":[{"iso":"eng"}],"date_updated":"2022-01-27T10:58:38Z","intvolume":"        65","publication_identifier":{"issn":["0003-0503"]},"article_processing_charge":"No","oa":1,"title":"Sublattice resolved spin wave transport through graphene fractional quantum Hall states as a probe of isospin order","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","day":"01","article_number":"B54. 00007","date_published":"2020-03-01T00:00:00Z","_id":"10693","quality_controlled":"1","conference":{"name":"APS: American Physical Society","end_date":"2020-03-06","start_date":"2020-03-02","location":"Denver, CO, United States"},"extern":"1","publisher":"American Physical Society"},{"alternative_title":["Bulletin of the American Physical Society"],"author":[{"orcid":"0000-0001-8223-8896","first_name":"Hryhoriy","last_name":"Polshyn","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"full_name":"Zhu, Jihang","first_name":"Jihang","last_name":"Zhu"},{"full_name":"Kumar, Manish","last_name":"Kumar","first_name":"Manish"},{"full_name":"Taniguchi, Takashi","first_name":"Takashi","last_name":"Taniguchi"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"full_name":"MacDonald, Allan","first_name":"Allan","last_name":"MacDonald"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"volume":65,"issue":"1","month":"03","year":"2020","publication_status":"published","language":[{"iso":"eng"}],"citation":{"chicago":"Polshyn, Hryhoriy, Jihang Zhu, Manish Kumar, Takashi Taniguchi, Kenji Watanabe, Allan MacDonald, and Andrea Young. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"H. Polshyn, J. Zhu, M. Kumar, T. Taniguchi, K. Watanabe, A. MacDonald, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","mla":"Polshyn, Hryhoriy, et al. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B51.00005, American Physical Society, 2020.","ista":"Polshyn H, Zhu J, Kumar M, Taniguchi T, Watanabe K, MacDonald A, Young A. 2020. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B51.00005.","ieee":"H. Polshyn <i>et al.</i>, “Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","ama":"Polshyn H, Zhu J, Kumar M, et al. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Polshyn, H., Zhu, J., Kumar, M., Taniguchi, T., Watanabe, K., MacDonald, A., &#38; Young, A. (2020). Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society."},"type":"conference","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B51.5"}],"date_created":"2022-01-28T10:09:19Z","oa_version":"Published Version","publication":"APS March Meeting 2020","status":"public","abstract":[{"lang":"eng","text":"We experimentally investigate twisted van der Waals heterostructures of monolayer graphene rotated with respect to a bernal stacked graphene bilayer. We report transport measurements for devices with twist angles between 0.9 and 1.4°. The electric field allows efficient tuning of the width, isolation and the topology of the moiré bands in this system. By comparing magnetoresistance measurements to numerical simulations, we develop an understanding of the band structure. Finally, we observe correlated states at half- and quarter-fillings, which arise when narrow moire sublattice band is isolated by energy gaps from dispersive bands. We investigate the effects of in-plane and out-of-plane magnetic field on these states and discuss the implication for their spin- and valley- polarization."}],"intvolume":"        65","date_updated":"2022-02-08T10:22:08Z","article_processing_charge":"No","publication_identifier":{"issn":["0003-0503"]},"day":"01","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures","oa":1,"_id":"10696","quality_controlled":"1","date_published":"2020-03-01T00:00:00Z","article_number":"B51.00005","publisher":"American Physical Society","extern":"1","conference":{"name":"APS: American Physical Society","end_date":"2020-03-06","start_date":"2020-03-02","location":"Denver, CO, United States"}},{"author":[{"full_name":"Zhang, Yuxuan","last_name":"Zhang","first_name":"Yuxuan"},{"first_name":"Marec","last_name":"Serlin","full_name":"Serlin, Marec"},{"full_name":"Tschirhart, Charles","last_name":"Tschirhart","first_name":"Charles"},{"orcid":"0000-0001-8223-8896","first_name":"Hryhoriy","last_name":"Polshyn","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"last_name":"Zhu","first_name":"Jiacheng","full_name":"Zhu, Jiacheng"},{"full_name":"Balents, Leon","last_name":"Balents","first_name":"Leon"},{"full_name":"Huber, Martin E.","last_name":"Huber","first_name":"Martin E."},{"last_name":"Taniguchi","first_name":"Takashi","full_name":"Taniguchi, Takashi"},{"last_name":"Watanabe","first_name":"Kenji","full_name":"Watanabe, Kenji"},{"last_name":"Young","first_name":"Andrea","full_name":"Young, Andrea"}],"alternative_title":["Bulletin of the American Physical Society"],"publication_status":"published","year":"2020","month":"03","related_material":{"record":[{"relation":"other","status":"public","id":"10619"}]},"issue":"1","volume":65,"abstract":[{"lang":"eng","text":"We report the observation of a quantized anomalous Hall effect in a moiré heterostructure consisting of twisted bilayer graphene aligned to an encapsulating hBN substrate. The effect occurs at a density of 3 electrons per superlattice unit cell, where we observe magnetic hysteresis and a Hall resistance quantized to within 0.1% of the resistance quantum at temperatures as high as 3K. In this first of 3 talks, I will describe the fabrication procedure for our device as well as basic transport characterization measurements. I will introduce the phenomenology of twisted bilayer graphene and present evidence for hBN alignment as manifested in the hierarchy of symmetry-breaking gaps and anomalous magnetoresistance."}],"status":"public","external_id":{"arxiv":["1907.00261"]},"date_created":"2022-01-28T10:28:35Z","publication":"APS March Meeting 2020","oa_version":"Published Version","main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.12","open_access":"1"}],"type":"conference","citation":{"chicago":"Zhang, Yuxuan, Marec Serlin, Charles Tschirhart, Hryhoriy Polshyn, Jiacheng Zhu, Leon Balents, Martin E. Huber, Takashi Taniguchi, Kenji Watanabe, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","short":"Y. Zhang, M. Serlin, C. Tschirhart, H. Polshyn, J. Zhu, L. Balents, M.E. Huber, T. Taniguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","mla":"Zhang, Yuxuan, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00012, American Physical Society, 2020.","ieee":"Y. Zhang <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","ista":"Zhang Y, Serlin M, Tschirhart C, Polshyn H, Zhu J, Balents L, Huber ME, Taniguchi T, Watanabe K, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00012.","ama":"Zhang Y, Serlin M, Tschirhart C, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","apa":"Zhang, Y., Serlin, M., Tschirhart, C., Polshyn, H., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society."},"language":[{"iso":"eng"}],"date_updated":"2023-02-21T15:57:52Z","arxiv":1,"intvolume":"        65","article_processing_charge":"No","oa":1,"title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","day":"01","article_number":"B59.00012","_id":"10697","date_published":"2020-03-01T00:00:00Z","quality_controlled":"1","conference":{"name":"APS: American Physical Society","start_date":"2020-03-02","location":"Denver, CO, United States","end_date":"2020-03-06"},"extern":"1","publisher":"American Physical Society","acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work."},{"related_material":{"record":[{"status":"public","id":"10619","relation":"other"}]},"issue":"1","volume":65,"month":"03","year":"2020","publication_status":"published","alternative_title":["Bulletin of the American Physical Society"],"author":[{"last_name":"Serlin","first_name":"Marec","full_name":"Serlin, Marec"},{"first_name":"Charles","last_name":"Tschirhart","full_name":"Tschirhart, Charles"},{"first_name":"Hryhoriy","orcid":"0000-0001-8223-8896","last_name":"Polshyn","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy"},{"full_name":"Zhang, Yuxuan","last_name":"Zhang","first_name":"Yuxuan"},{"full_name":"Zhu, Jiacheng","first_name":"Jiacheng","last_name":"Zhu"},{"full_name":"Huber, Martin E.","first_name":"Martin E.","last_name":"Huber"},{"full_name":"Balents, Leon","first_name":"Leon","last_name":"Balents"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"full_name":"Tanaguchi, Takashi","first_name":"Takashi","last_name":"Tanaguchi"},{"first_name":"Andrea","last_name":"Young","full_name":"Young, Andrea"}],"intvolume":"        65","date_updated":"2023-02-21T15:57:52Z","arxiv":1,"citation":{"chicago":"Serlin, Marec, Charles Tschirhart, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Martin E. Huber, Leon Balents, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","ama":"Serlin M, Tschirhart C, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Serlin M, Tschirhart C, Polshyn H, Zhang Y, Zhu J, Huber ME, Balents L, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00011.","ieee":"M. Serlin <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","apa":"Serlin, M., Tschirhart, C., Polshyn, H., Zhang, Y., Zhu, J., Huber, M. E., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","short":"M. Serlin, C. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, M.E. Huber, L. Balents, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020.","mla":"Serlin, Marec, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part II: Temperature Dependence and Current Switching.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00011, American Physical Society, 2020."},"language":[{"iso":"eng"}],"date_created":"2022-01-28T10:46:57Z","oa_version":"Published Version","publication":"APS March Meeting 2020","main_file_link":[{"open_access":"1","url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.11"}],"type":"conference","abstract":[{"lang":"eng","text":"This is the second of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. I will compare the qualitative and quantitative features of this observed quantum anomalous Hall state to traditional systems engineered from thin film (Bi,Sb)2Te3 topological insulators. In particular, we find that the measured electronic energy gap of ~30K is several times higher than the Curie temperature, consistent with a lack of disorder associated with magnetic dopants. In this system, the quantization arises from spontaneous ferromagnetic polarization into a single spin and valley moiré subband, which is topological despite the lack of spin orbit coupling. I will also discuss the observation of current induced switching, which allows the magnetic state of the heterostructure to be controllably reversed with currents as small as a few nanoamperes."}],"external_id":{"arxiv":["1907.00261"]},"status":"public","day":"01","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part II: Temperature dependence and current switching","article_processing_charge":"No","acknowledgement":"I would like to thank the MURI Program, AFOSR, Sloan Foundation, and the ARO for their generous support of this work.","publisher":"American Physical Society","extern":"1","conference":{"end_date":"2020-03-06","location":"Denver, CO, United States","start_date":"2020-03-02","name":"APS: American Physical Society"},"date_published":"2020-03-01T00:00:00Z","_id":"10698","quality_controlled":"1","article_number":"B59.00011"},{"citation":{"chicago":"Tschirhart, Charles, Marec Serlin, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Leon Balents, Martin E. Huber, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” In <i>APS March Meeting 2020</i>, Vol. 65. American Physical Society, 2020.","apa":"Tschirhart, C., Serlin, M., Polshyn, H., Zhang, Y., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In <i>APS March Meeting 2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.","ieee":"C. Tschirhart <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry,” in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.","ama":"Tschirhart C, Serlin M, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.","ista":"Tschirhart C, Serlin M, Polshyn H, Zhang Y, Zhu J, Balents L, Huber ME, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00013.","mla":"Tschirhart, Charles, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” <i>APS March Meeting 2020</i>, vol. 65, no. 1, B59.00013, American Physical Society, 2020.","short":"C. Tschirhart, M. Serlin, H. Polshyn, Y. Zhang, J. Zhu, L. Balents, M.E. Huber, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020."},"language":[{"iso":"eng"}],"abstract":[{"text":"This is the third of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. In this segment I will present scanning probe magnetometry data acquired using a nanoSQUID-on-tip microscope, which provides ~150 nm spatial resolution and a field sensitivity of ~10 nT/rtHz. We study the distribution of magnetic domains within the device as a function of density, magnetic field training, and DC current. Our data allow us to constrain the magnitude of the orbital magnetic moment of the electrons in the QAH state. Comparison with simultaneously acquired transport data allows us to precisely correlate single domain dynamics with discrete jumps in the observed anomalous Hall signal.","lang":"eng"}],"external_id":{"arxiv":["1907.00261"]},"status":"public","date_created":"2022-01-28T10:57:49Z","oa_version":"Published Version","publication":"APS March Meeting 2020","main_file_link":[{"url":"https://meetings.aps.org/Meeting/MAR20/Session/B59.13","open_access":"1"}],"type":"conference","date_updated":"2023-02-21T15:57:52Z","arxiv":1,"intvolume":"        65","author":[{"first_name":"Charles","last_name":"Tschirhart","full_name":"Tschirhart, Charles"},{"first_name":"Marec","last_name":"Serlin","full_name":"Serlin, Marec"},{"last_name":"Polshyn","first_name":"Hryhoriy","orcid":"0000-0001-8223-8896","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","full_name":"Polshyn, Hryhoriy"},{"first_name":"Yuxuan","last_name":"Zhang","full_name":"Zhang, Yuxuan"},{"first_name":"Jiacheng","last_name":"Zhu","full_name":"Zhu, Jiacheng"},{"last_name":"Balents","first_name":"Leon","full_name":"Balents, Leon"},{"first_name":"Martin E.","last_name":"Huber","full_name":"Huber, Martin E."},{"full_name":"Watanabe, Kenji","last_name":"Watanabe","first_name":"Kenji"},{"full_name":"Tanaguchi, Takashi","last_name":"Tanaguchi","first_name":"Takashi"},{"first_name":"Andrea","last_name":"Young","full_name":"Young, Andrea"}],"alternative_title":["Bulletin of the American Physical Society"],"month":"03","related_material":{"record":[{"relation":"other","id":"10619","status":"public"}]},"issue":"1","volume":65,"publication_status":"published","year":"2020","article_number":"B59.00013","_id":"10699","date_published":"2020-03-01T00:00:00Z","quality_controlled":"1","publisher":"American Physical Society","acknowledgement":"I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work. I would also like to thank the NSF GRFP and the Hertz foundation for their generous support of my graduate studies.","conference":{"end_date":"2020-03-06","start_date":"2020-03-02","location":"Denver, CO, United States","name":"APS: American Physical Society"},"extern":"1","publication_identifier":{"issn":["0003-0503"]},"article_processing_charge":"No","day":"01","oa":1,"title":"Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"extern":"1","acknowledgement":"We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST (JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard Foundation and and Alfred. P. Sloan Foundation.","doi":"10.1038/s41567-019-0729-8","publisher":"Springer Nature","date_published":"2020-02-01T00:00:00Z","_id":"10701","quality_controlled":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"title":"Skyrmion solids in monolayer graphene","day":"01","article_processing_charge":"No","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"intvolume":"        16","date_updated":"2022-01-31T07:10:07Z","arxiv":1,"oa_version":"Preprint","publication":"Nature Physics","date_created":"2022-01-28T12:04:09Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1904.11485"}],"type":"journal_article","abstract":[{"text":"Partially filled Landau levels host competing electronic orders. For example, electron solids may prevail close to integer filling of the Landau levels before giving way to fractional quantum Hall liquids at higher carrier density1,2. Here, we report the observation of an electron solid with non-collinear spin texture in monolayer graphene, consistent with solidification of skyrmions3—topological spin textures characterized by quantized electrical charge4,5. We probe the spin texture of the solids using a modified Corbino geometry that allows ferromagnetic magnons to be launched and detected6,7. We find that magnon transport is highly efficient when one Landau level is filled (ν=1), consistent with quantum Hall ferromagnetic spin polarization. However, even minimal doping immediately quenches the magnon signal while leaving the vanishing low-temperature charge conductivity unchanged. Our results can be understood by the formation of a solid of charged skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay. Data near fractional fillings show evidence of several fractional skyrmion solids, suggesting that graphene hosts a highly tunable landscape of coupled spin and charge orders.","lang":"eng"}],"status":"public","external_id":{"arxiv":["1904.11485"]},"citation":{"short":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics 16 (2020) 154–158.","mla":"Zhou, Haoxin, et al. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>, vol. 16, no. 2, Springer Nature, 2020, pp. 154–58, doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>.","ieee":"H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Skyrmion solids in monolayer graphene,” <i>Nature Physics</i>, vol. 16, no. 2. Springer Nature, pp. 154–158, 2020.","ista":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2020. Skyrmion solids in monolayer graphene. Nature Physics. 16(2), 154–158.","ama":"Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. 2020;16(2):154-158. doi:<a href=\"https://doi.org/10.1038/s41567-019-0729-8\">10.1038/s41567-019-0729-8</a>","apa":"Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., &#38; Young, A. F. (2020). Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>","chicago":"Zhou, Haoxin, Hryhoriy Polshyn, Takashi Taniguchi, Kenji Watanabe, and Andrea F. Young. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41567-019-0729-8\">https://doi.org/10.1038/s41567-019-0729-8</a>."},"article_type":"original","language":[{"iso":"eng"}],"year":"2020","publication_status":"published","issue":"2","volume":16,"month":"02","author":[{"full_name":"Zhou, Haoxin","first_name":"Haoxin","last_name":"Zhou"},{"orcid":"0000-0001-8223-8896","first_name":"Hryhoriy","last_name":"Polshyn","full_name":"Polshyn, Hryhoriy","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48"},{"full_name":"Taniguchi, Takashi","first_name":"Takashi","last_name":"Taniguchi"},{"full_name":"Watanabe, Kenji","first_name":"Kenji","last_name":"Watanabe"},{"full_name":"Young, Andrea F.","last_name":"Young","first_name":"Andrea F."}],"page":"154-158"},{"department":[{"_id":"HeEd"}],"day":"01","title":"Coxeter triangulations have good quality","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["1661-8289"],"issn":["1661-8270"]},"article_processing_charge":"Yes (via OA deal)","publisher":"Springer Nature","doi":"10.1007/s11786-020-00461-5","file":[{"file_size":872275,"file_name":"2020_MathCompScie_Choudhary.pdf","file_id":"8783","date_updated":"2020-11-20T10:18:02Z","checksum":"1d145f3ab50ccee735983cb89236e609","success":1,"access_level":"open_access","creator":"dernst","relation":"main_file","content_type":"application/pdf","date_created":"2020-11-20T10:18:02Z"}],"_id":"7567","quality_controlled":"1","date_published":"2020-03-01T00:00:00Z","month":"03","volume":14,"file_date_updated":"2020-11-20T10:18:02Z","publication_status":"published","year":"2020","page":"141-176","author":[{"first_name":"Aruni","last_name":"Choudhary","full_name":"Choudhary, Aruni"},{"last_name":"Kachanovich","first_name":"Siargey","full_name":"Kachanovich, Siargey"},{"orcid":"0000-0002-7472-2220","first_name":"Mathijs","last_name":"Wintraecken","full_name":"Wintraecken, Mathijs","id":"307CFBC8-F248-11E8-B48F-1D18A9856A87"}],"project":[{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"},{"grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020"}],"ddc":["510"],"date_updated":"2025-04-14T07:44:03Z","intvolume":"        14","language":[{"iso":"eng"}],"citation":{"chicago":"Choudhary, Aruni, Siargey Kachanovich, and Mathijs Wintraecken. “Coxeter Triangulations Have Good Quality.” <i>Mathematics in Computer Science</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s11786-020-00461-5\">https://doi.org/10.1007/s11786-020-00461-5</a>.","ama":"Choudhary A, Kachanovich S, Wintraecken M. Coxeter triangulations have good quality. <i>Mathematics in Computer Science</i>. 2020;14:141-176. doi:<a href=\"https://doi.org/10.1007/s11786-020-00461-5\">10.1007/s11786-020-00461-5</a>","ieee":"A. Choudhary, S. Kachanovich, and M. Wintraecken, “Coxeter triangulations have good quality,” <i>Mathematics in Computer Science</i>, vol. 14. Springer Nature, pp. 141–176, 2020.","ista":"Choudhary A, Kachanovich S, Wintraecken M. 2020. Coxeter triangulations have good quality. Mathematics in Computer Science. 14, 141–176.","apa":"Choudhary, A., Kachanovich, S., &#38; Wintraecken, M. (2020). Coxeter triangulations have good quality. <i>Mathematics in Computer Science</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11786-020-00461-5\">https://doi.org/10.1007/s11786-020-00461-5</a>","short":"A. Choudhary, S. Kachanovich, M. Wintraecken, Mathematics in Computer Science 14 (2020) 141–176.","mla":"Choudhary, Aruni, et al. “Coxeter Triangulations Have Good Quality.” <i>Mathematics in Computer Science</i>, vol. 14, Springer Nature, 2020, pp. 141–76, doi:<a href=\"https://doi.org/10.1007/s11786-020-00461-5\">10.1007/s11786-020-00461-5</a>."},"article_type":"original","ec_funded":1,"has_accepted_license":"1","status":"public","abstract":[{"text":"Coxeter triangulations are triangulations of Euclidean space based on a single simplex. By this we mean that given an individual simplex we can recover the entire triangulation of Euclidean space by inductively reflecting in the faces of the simplex. In this paper we establish that the quality of the simplices in all Coxeter triangulations is O(1/d−−√) of the quality of regular simplex. We further investigate the Delaunay property for these triangulations. Moreover, we consider an extension of the Delaunay property, namely protection, which is a measure of non-degeneracy of a Delaunay triangulation. In particular, one family of Coxeter triangulations achieves the protection O(1/d2). We conjecture that both bounds are optimal for triangulations in Euclidean space.","lang":"eng"}],"type":"journal_article","corr_author":"1","publication":"Mathematics in Computer Science","oa_version":"Published Version","date_created":"2020-03-05T13:30:18Z","scopus_import":"1"},{"day":"25","department":[{"_id":"CaGu"},{"_id":"GaTk"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"The relation between crosstalk and gene regulation form revisited","oa":1,"article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"issn":["1553-7358"]},"file":[{"content_type":"application/pdf","date_created":"2020-03-09T15:12:21Z","relation":"main_file","creator":"dernst","access_level":"open_access","checksum":"5239dd134dc6e1c71fe7b3ce2953da37","date_updated":"2020-07-14T12:48:00Z","file_id":"7579","file_name":"2020_PlosCompBio_Grah.pdf","file_size":2209325}],"isi":1,"doi":"10.1371/journal.pcbi.1007642","publisher":"Public Library of Science","quality_controlled":"1","_id":"7569","date_published":"2020-02-25T00:00:00Z","article_number":"e1007642","volume":16,"related_material":{"record":[{"relation":"research_data","id":"9716","status":"deleted"},{"relation":"research_data","id":"9776","status":"public"},{"id":"9779","status":"public","relation":"research_data"},{"relation":"research_data","id":"9777","status":"public"},{"relation":"dissertation_contains","id":"8155","status":"public"}]},"issue":"2","month":"02","year":"2020","publication_status":"published","file_date_updated":"2020-07-14T12:48:00Z","pmid":1,"author":[{"full_name":"Grah, Rok","id":"483E70DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2539-3560","first_name":"Rok","last_name":"Grah"},{"full_name":"Friedlander, Tamar","first_name":"Tamar","last_name":"Friedlander"}],"intvolume":"        16","ddc":["000","570"],"date_updated":"2026-04-08T07:25:08Z","language":[{"iso":"eng"}],"article_type":"original","citation":{"apa":"Grah, R., &#38; Friedlander, T. (2020). The relation between crosstalk and gene regulation form revisited. <i>PLOS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">https://doi.org/10.1371/journal.pcbi.1007642</a>","ista":"Grah R, Friedlander T. 2020. The relation between crosstalk and gene regulation form revisited. PLOS Computational Biology. 16(2), e1007642.","ama":"Grah R, Friedlander T. The relation between crosstalk and gene regulation form revisited. <i>PLOS Computational Biology</i>. 2020;16(2). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">10.1371/journal.pcbi.1007642</a>","ieee":"R. Grah and T. Friedlander, “The relation between crosstalk and gene regulation form revisited,” <i>PLOS Computational Biology</i>, vol. 16, no. 2. Public Library of Science, 2020.","mla":"Grah, Rok, and Tamar Friedlander. “The Relation between Crosstalk and Gene Regulation Form Revisited.” <i>PLOS Computational Biology</i>, vol. 16, no. 2, e1007642, Public Library of Science, 2020, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">10.1371/journal.pcbi.1007642</a>.","short":"R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).","chicago":"Grah, Rok, and Tamar Friedlander. “The Relation between Crosstalk and Gene Regulation Form Revisited.” <i>PLOS Computational Biology</i>. Public Library of Science, 2020. <a href=\"https://doi.org/10.1371/journal.pcbi.1007642\">https://doi.org/10.1371/journal.pcbi.1007642</a>."},"type":"journal_article","oa_version":"Published Version","publication":"PLOS Computational Biology","date_created":"2020-03-06T07:39:38Z","scopus_import":"1","has_accepted_license":"1","status":"public","external_id":{"pmid":["32097416"],"isi":["000526725200019"]},"abstract":[{"lang":"eng","text":"Genes differ in the frequency at which they are expressed and in the form of regulation used to control their activity. In particular, positive or negative regulation can lead to activation of a gene in response to an external signal. Previous works proposed that the form of regulation of a gene correlates with its frequency of usage: positive regulation when the gene is frequently expressed and negative regulation when infrequently expressed. Such network design means that, in the absence of their regulators, the genes are found in their least required activity state, hence regulatory intervention is often necessary. Due to the multitude of genes and regulators, spurious binding and unbinding events, called “crosstalk”, could occur. To determine how the form of regulation affects the global crosstalk in the network, we used a mathematical model that includes multiple regulators and multiple target genes. We found that crosstalk depends non-monotonically on the availability of regulators. Our analysis showed that excess use of regulation entailed by the formerly suggested network design caused high crosstalk levels in a large part of the parameter space. We therefore considered the opposite ‘idle’ design, where the default unregulated state of genes is their frequently required activity state. We found, that ‘idle’ design minimized the use of regulation and thus minimized crosstalk. In addition, we estimated global crosstalk of S. cerevisiae using transcription factors binding data. We demonstrated that even partial network data could suffice to estimate its global crosstalk, suggesting its applicability to additional organisms. We found that S. cerevisiae estimated crosstalk is lower than that of a random network, suggesting that natural selection reduces crosstalk. In summary, our study highlights a new type of protein production cost which is typically overlooked: that of regulatory interference caused by the presence of excess regulators in the cell. It demonstrates the importance of whole-network descriptions, which could show effects missed by single-gene models."}]},{"arxiv":1,"ddc":["530"],"date_updated":"2023-08-18T07:01:07Z","intvolume":"        10","status":"public","external_id":{"isi":["000517969300001"],"arxiv":["1905.08564"]},"has_accepted_license":"1","abstract":[{"text":"The relaxation of few-body quantum systems can strongly depend on the initial state when the system’s semiclassical phase space is mixed; i.e., regions of chaotic motion coexist with regular islands. In recent years, there has been much effort to understand the process of thermalization in strongly interacting quantum systems that often lack an obvious semiclassical limit. The time-dependent variational principle (TDVP) allows one to systematically derive an effective classical (nonlinear) dynamical system by projecting unitary many-body dynamics onto a manifold of weakly entangled variational states. We demonstrate that such dynamical systems generally possess mixed phase space. When TDVP errors are small, the mixed phase space leaves a footprint on the exact dynamics of the quantum model. For example, when the system is initialized in a state belonging to a stable periodic orbit or the surrounding regular region, it exhibits persistent many-body quantum revivals. As a proof of principle, we identify new types of “quantum many-body scars,” i.e., initial states that lead to long-time oscillations in a model of interacting Rydberg atoms in one and two dimensions. Intriguingly, the initial states that give rise to most robust revivals are typically entangled states. On the other hand, even when TDVP errors are large, as in the thermalizing tilted-field Ising model, initializing the system in a regular region of phase space leads to a surprising slowdown of thermalization. Our work establishes TDVP as a method for identifying interacting quantum systems with anomalous dynamics in arbitrary dimensions. Moreover, the mixed phase space classical variational equations allow one to find slowly thermalizing initial conditions in interacting models. Our results shed light on a link between classical and quantum chaos, pointing toward possible extensions of the classical Kolmogorov-Arnold-Moser theorem to quantum systems.","lang":"eng"}],"type":"journal_article","date_created":"2020-03-08T18:02:01Z","scopus_import":"1","publication":"Physical Review X","oa_version":"Published Version","language":[{"iso":"eng"}],"citation":{"chicago":"Michailidis, Alexios, C. J. Turner, Z. Papić, D. A. Abanin, and Maksym Serbyn. “Slow Quantum Thermalization and Many-Body Revivals from Mixed Phase Space.” <i>Physical Review X</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/physrevx.10.011055\">https://doi.org/10.1103/physrevx.10.011055</a>.","mla":"Michailidis, Alexios, et al. “Slow Quantum Thermalization and Many-Body Revivals from Mixed Phase Space.” <i>Physical Review X</i>, vol. 10, no. 1, 011055, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/physrevx.10.011055\">10.1103/physrevx.10.011055</a>.","short":"A. Michailidis, C.J. Turner, Z. Papić, D.A. Abanin, M. Serbyn, Physical Review X 10 (2020).","apa":"Michailidis, A., Turner, C. J., Papić, Z., Abanin, D. A., &#38; Serbyn, M. (2020). Slow quantum thermalization and many-body revivals from mixed phase space. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevx.10.011055\">https://doi.org/10.1103/physrevx.10.011055</a>","ieee":"A. Michailidis, C. J. Turner, Z. Papić, D. A. Abanin, and M. Serbyn, “Slow quantum thermalization and many-body revivals from mixed phase space,” <i>Physical Review X</i>, vol. 10, no. 1. American Physical Society, 2020.","ama":"Michailidis A, Turner CJ, Papić Z, Abanin DA, Serbyn M. Slow quantum thermalization and many-body revivals from mixed phase space. <i>Physical Review X</i>. 2020;10(1). doi:<a href=\"https://doi.org/10.1103/physrevx.10.011055\">10.1103/physrevx.10.011055</a>","ista":"Michailidis A, Turner CJ, Papić Z, Abanin DA, Serbyn M. 2020. Slow quantum thermalization and many-body revivals from mixed phase space. Physical Review X. 10(1), 011055."},"article_type":"original","file_date_updated":"2020-07-14T12:48:00Z","publication_status":"published","year":"2020","month":"03","volume":10,"issue":"1","related_material":{"link":[{"url":"https://ist.ac.at/en/news/classical-physics-helps-predict-fate-of-interacting-quantum-systems/","description":"News on IST Homepage","relation":"press_release"}]},"author":[{"first_name":"Alexios","orcid":"0000-0002-8443-1064","last_name":"Michailidis","id":"36EBAD38-F248-11E8-B48F-1D18A9856A87","full_name":"Michailidis, Alexios"},{"first_name":"C. J.","last_name":"Turner","full_name":"Turner, C. J."},{"full_name":"Papić, Z.","first_name":"Z.","last_name":"Papić"},{"full_name":"Abanin, D. A.","first_name":"D. A.","last_name":"Abanin"},{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","first_name":"Maksym","orcid":"0000-0002-2399-5827","last_name":"Serbyn"}],"publisher":"American Physical Society","file":[{"checksum":"4b3f2c13873d35230173c73d0e11c408","date_updated":"2020-07-14T12:48:00Z","file_id":"7581","file_name":"2020_PhysicalReviewX_Michailidis.pdf","file_size":17828638,"content_type":"application/pdf","date_created":"2020-03-12T12:13:07Z","relation":"main_file","creator":"dernst","access_level":"open_access"}],"isi":1,"doi":"10.1103/physrevx.10.011055","article_number":"011055","_id":"7570","quality_controlled":"1","date_published":"2020-03-04T00:00:00Z","title":"Slow quantum thermalization and many-body revivals from mixed phase space","oa":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","department":[{"_id":"MaSe"}],"day":"04","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"issn":["2160-3308"]},"article_processing_charge":"No"},{"publication_status":"published","year":"2020","month":"02","related_material":{"record":[{"status":"public","id":"8358","relation":"part_of_dissertation"}]},"volume":158,"author":[{"last_name":"Dos Santos Caldas","first_name":"Paulo R","orcid":"0000-0001-6730-4461","id":"38FCDB4C-F248-11E8-B48F-1D18A9856A87","full_name":"Dos Santos Caldas, Paulo R"},{"id":"40136C2A-F248-11E8-B48F-1D18A9856A87","full_name":"Radler, Philipp","first_name":"Philipp","orcid":"0000-0001-9198-2182 ","last_name":"Radler"},{"last_name":"Sommer","first_name":"Christoph M","orcid":"0000-0003-1216-9105","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","full_name":"Sommer, Christoph M"},{"first_name":"Martin","orcid":"0000-0001-7309-9724","last_name":"Loose","id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin"}],"alternative_title":["Methods in Cell Biology"],"page":"145-161","date_updated":"2026-04-08T07:26:30Z","intvolume":"       158","project":[{"grant_number":"679239","call_identifier":"H2020","_id":"2595697A-B435-11E9-9278-68D0E5697425","name":"Self-Organization of the Bacterial Cell"},{"name":"Reconstitution of Bacterial Cell Division Using Purified Components","_id":"260D98C8-B435-11E9-9278-68D0E5697425"}],"abstract":[{"lang":"eng","text":"The polymerization–depolymerization dynamics of cytoskeletal proteins play essential roles in the self-organization of cytoskeletal structures, in eukaryotic as well as prokaryotic cells. While advances in fluorescence microscopy and in vitro reconstitution experiments have helped to study the dynamic properties of these complex systems, methods that allow to collect and analyze large quantitative datasets of the underlying polymer dynamics are still missing. Here, we present a novel image analysis workflow to study polymerization dynamics of active filaments in a nonbiased, highly automated manner. Using treadmilling filaments of the bacterial tubulin FtsZ as an example, we demonstrate that our method is able to specifically detect, track and analyze growth and shrinkage of polymers, even in dense networks of filaments. We believe that this automated method can facilitate the analysis of a large variety of dynamic cytoskeletal systems, using standard time-lapse movies obtained from experiments in vitro as well as in the living cell. Moreover, we provide scripts implementing this method as supplementary material."}],"status":"public","external_id":{"isi":["000611826500008"]},"scopus_import":"1","oa_version":"Preprint","publication":"Methods in Cell Biology","date_created":"2020-03-08T23:00:47Z","type":"book_chapter","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/839571"}],"citation":{"mla":"Dos Santos Caldas, Paulo R., et al. “Computational Analysis of Filament Polymerization Dynamics in Cytoskeletal Networks.” <i>Methods in Cell Biology</i>, edited by Phong  Tran, vol. 158, Elsevier, 2020, pp. 145–61, doi:<a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">10.1016/bs.mcb.2020.01.006</a>.","short":"P.R. Dos Santos Caldas, P. Radler, C.M. Sommer, M. Loose, in:, P. Tran (Ed.), Methods in Cell Biology, Elsevier, 2020, pp. 145–161.","apa":"Dos Santos Caldas, P. R., Radler, P., Sommer, C. M., &#38; Loose, M. (2020). Computational analysis of filament polymerization dynamics in cytoskeletal networks. In P. Tran (Ed.), <i>Methods in Cell Biology</i> (Vol. 158, pp. 145–161). Elsevier. <a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">https://doi.org/10.1016/bs.mcb.2020.01.006</a>","ama":"Dos Santos Caldas PR, Radler P, Sommer CM, Loose M. Computational analysis of filament polymerization dynamics in cytoskeletal networks. In: Tran P, ed. <i>Methods in Cell Biology</i>. Vol 158. Elsevier; 2020:145-161. doi:<a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">10.1016/bs.mcb.2020.01.006</a>","ista":"Dos Santos Caldas PR, Radler P, Sommer CM, Loose M. 2020.Computational analysis of filament polymerization dynamics in cytoskeletal networks. In: Methods in Cell Biology. Methods in Cell Biology, vol. 158, 145–161.","ieee":"P. R. Dos Santos Caldas, P. Radler, C. M. Sommer, and M. Loose, “Computational analysis of filament polymerization dynamics in cytoskeletal networks,” in <i>Methods in Cell Biology</i>, vol. 158, P. Tran, Ed. Elsevier, 2020, pp. 145–161.","chicago":"Dos Santos Caldas, Paulo R, Philipp Radler, Christoph M Sommer, and Martin Loose. “Computational Analysis of Filament Polymerization Dynamics in Cytoskeletal Networks.” In <i>Methods in Cell Biology</i>, edited by Phong  Tran, 158:145–61. Elsevier, 2020. <a href=\"https://doi.org/10.1016/bs.mcb.2020.01.006\">https://doi.org/10.1016/bs.mcb.2020.01.006</a>."},"ec_funded":1,"language":[{"iso":"eng"}],"oa":1,"title":"Computational analysis of filament polymerization dynamics in cytoskeletal networks","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"MaLo"}],"day":"27","editor":[{"full_name":"Tran, Phong ","last_name":"Tran","first_name":"Phong "}],"publication_identifier":{"issn":["0091-679X"]},"article_processing_charge":"No","publisher":"Elsevier","doi":"10.1016/bs.mcb.2020.01.006","isi":1,"date_published":"2020-02-27T00:00:00Z","_id":"7572","quality_controlled":"1"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Homogenisation of one-dimensional discrete optimal transport","oa":1,"day":"01","department":[{"_id":"JaMa"}],"article_processing_charge":"No","publication_identifier":{"issn":["0021-7824"]},"doi":"10.1016/j.matpur.2020.02.008","isi":1,"acknowledgement":"J.M. gratefully acknowledges support by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No 716117). J.M. and L.P. also acknowledge support from the Austrian Science Fund (FWF), grants No F65 and W1245. E.K. gratefully acknowledges support by the German Research Foundation through the Hausdorff Center for Mathematics and the Collaborative Research Center 1060. P.G. is partially funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 350398276.","publisher":"Elsevier","_id":"7573","quality_controlled":"1","date_published":"2020-07-01T00:00:00Z","year":"2020","publication_status":"published","volume":139,"related_material":{"record":[{"status":"public","id":"10030","relation":"dissertation_contains"}]},"issue":"7","month":"07","author":[{"full_name":"Gladbach, Peter","last_name":"Gladbach","first_name":"Peter"},{"last_name":"Kopfer","first_name":"Eva","full_name":"Kopfer, Eva"},{"first_name":"Jan","orcid":"0000-0002-0845-1338","last_name":"Maas","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87","full_name":"Maas, Jan"},{"id":"30AD2CBC-F248-11E8-B48F-1D18A9856A87","full_name":"Portinale, Lorenzo","last_name":"Portinale","first_name":"Lorenzo"}],"page":"204-234","intvolume":"       139","arxiv":1,"date_updated":"2026-04-08T07:00:03Z","project":[{"grant_number":"716117","call_identifier":"H2020","_id":"256E75B8-B435-11E9-9278-68D0E5697425","name":"Optimal Transport and Stochastic Dynamics"},{"grant_number":"F06504","call_identifier":"FWF","name":"Taming Complexity in Partial Differential Systems","_id":"260482E2-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FWF","name":"Dissipation and dispersion in nonlinear partial differential equations","_id":"260788DE-B435-11E9-9278-68D0E5697425","grant_number":"W1245"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1905.05757"}],"type":"journal_article","date_created":"2020-03-08T23:00:47Z","publication":"Journal de Mathematiques Pures et Appliquees","scopus_import":"1","oa_version":"Preprint","external_id":{"isi":["000539439400008"],"arxiv":["1905.05757"]},"status":"public","abstract":[{"text":"This paper deals with dynamical optimal transport metrics defined by spatial discretisation of the Benamou–Benamou formula for the Kantorovich metric . Such metrics appear naturally in discretisations of -gradient flow formulations for dissipative PDE. However, it has recently been shown that these metrics do not in general converge to , unless strong geometric constraints are imposed on the discrete mesh. In this paper we prove that, in a 1-dimensional periodic setting, discrete transport metrics converge to a limiting transport metric with a non-trivial effective mobility. This mobility depends sensitively on the geometry of the mesh and on the non-local mobility at the discrete level. Our result quantifies to what extent discrete transport can make use of microstructure in the mesh to reduce the cost of transport.","lang":"eng"}],"language":[{"iso":"eng"}],"article_type":"original","ec_funded":1,"citation":{"ama":"Gladbach P, Kopfer E, Maas J, Portinale L. Homogenisation of one-dimensional discrete optimal transport. <i>Journal de Mathematiques Pures et Appliquees</i>. 2020;139(7):204-234. doi:<a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">10.1016/j.matpur.2020.02.008</a>","ista":"Gladbach P, Kopfer E, Maas J, Portinale L. 2020. Homogenisation of one-dimensional discrete optimal transport. Journal de Mathematiques Pures et Appliquees. 139(7), 204–234.","ieee":"P. Gladbach, E. Kopfer, J. Maas, and L. Portinale, “Homogenisation of one-dimensional discrete optimal transport,” <i>Journal de Mathematiques Pures et Appliquees</i>, vol. 139, no. 7. Elsevier, pp. 204–234, 2020.","apa":"Gladbach, P., Kopfer, E., Maas, J., &#38; Portinale, L. (2020). Homogenisation of one-dimensional discrete optimal transport. <i>Journal de Mathematiques Pures et Appliquees</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">https://doi.org/10.1016/j.matpur.2020.02.008</a>","short":"P. Gladbach, E. Kopfer, J. Maas, L. Portinale, Journal de Mathematiques Pures et Appliquees 139 (2020) 204–234.","mla":"Gladbach, Peter, et al. “Homogenisation of One-Dimensional Discrete Optimal Transport.” <i>Journal de Mathematiques Pures et Appliquees</i>, vol. 139, no. 7, Elsevier, 2020, pp. 204–34, doi:<a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">10.1016/j.matpur.2020.02.008</a>.","chicago":"Gladbach, Peter, Eva Kopfer, Jan Maas, and Lorenzo Portinale. “Homogenisation of One-Dimensional Discrete Optimal Transport.” <i>Journal de Mathematiques Pures et Appliquees</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.matpur.2020.02.008\">https://doi.org/10.1016/j.matpur.2020.02.008</a>."}},{"publisher":"National Academy of Sciences","isi":1,"doi":"10.1073/pnas.1921027117","_id":"7580","quality_controlled":"1","date_published":"2020-03-24T00:00:00Z","department":[{"_id":"MaLo"},{"_id":"CaBe"}],"day":"24","title":"Stochastic activation and bistability in a Rab GTPase regulatory network","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"article_processing_charge":"No","project":[{"_id":"2599F062-B435-11E9-9278-68D0E5697425","name":"Reconstitution of cell polarity and axis determination in a cell-free system","grant_number":"RGY0083/2016"}],"date_updated":"2026-04-08T07:24:55Z","intvolume":"       117","language":[{"iso":"eng"}],"article_type":"original","citation":{"chicago":"Bezeljak, Urban, Hrushikesh Loya, Beata M Kaczmarek, Timothy E. Saunders, and Martin Loose. “Stochastic Activation and Bistability in a Rab GTPase Regulatory Network.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2020. <a href=\"https://doi.org/10.1073/pnas.1921027117\">https://doi.org/10.1073/pnas.1921027117</a>.","short":"U. Bezeljak, H. Loya, B.M. Kaczmarek, T.E. Saunders, M. Loose, Proceedings of the National Academy of Sciences of the United States of America 117 (2020) 6504–6549.","mla":"Bezeljak, Urban, et al. “Stochastic Activation and Bistability in a Rab GTPase Regulatory Network.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 117, no. 12, National Academy of Sciences, 2020, pp. 6504–49, doi:<a href=\"https://doi.org/10.1073/pnas.1921027117\">10.1073/pnas.1921027117</a>.","ama":"Bezeljak U, Loya H, Kaczmarek BM, Saunders TE, Loose M. Stochastic activation and bistability in a Rab GTPase regulatory network. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2020;117(12):6504-6549. doi:<a href=\"https://doi.org/10.1073/pnas.1921027117\">10.1073/pnas.1921027117</a>","ista":"Bezeljak U, Loya H, Kaczmarek BM, Saunders TE, Loose M. 2020. Stochastic activation and bistability in a Rab GTPase regulatory network. Proceedings of the National Academy of Sciences of the United States of America. 117(12), 6504–6549.","ieee":"U. Bezeljak, H. Loya, B. M. Kaczmarek, T. E. Saunders, and M. Loose, “Stochastic activation and bistability in a Rab GTPase regulatory network,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 117, no. 12. National Academy of Sciences, pp. 6504–6549, 2020.","apa":"Bezeljak, U., Loya, H., Kaczmarek, B. M., Saunders, T. E., &#38; Loose, M. (2020). Stochastic activation and bistability in a Rab GTPase regulatory network. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1921027117\">https://doi.org/10.1073/pnas.1921027117</a>"},"status":"public","external_id":{"pmid":["32161136"],"isi":["000521821800040"]},"abstract":[{"text":"The eukaryotic endomembrane system is controlled by small GTPases of the Rab family, which are activated at defined times and locations in a switch-like manner. While this switch is well understood for an individual protein, how regulatory networks produce intracellular activity patterns is currently not known. Here, we combine in vitro reconstitution experiments with computational modeling to study a minimal Rab5 activation network. We find that the molecular interactions in this system give rise to a positive feedback and bistable collective switching of Rab5. Furthermore, we find that switching near the critical point is intrinsically stochastic and provide evidence that controlling the inactive population of Rab5 on the membrane can shape the network response. Notably, we demonstrate that collective switching can spread on the membrane surface as a traveling wave of Rab5 activation. Together, our findings reveal how biochemical signaling networks control vesicle trafficking pathways and how their nonequilibrium properties define the spatiotemporal organization of the cell.","lang":"eng"}],"type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/776567"}],"publication":"Proceedings of the National Academy of Sciences of the United States of America","scopus_import":"1","date_created":"2020-03-12T05:32:26Z","oa_version":"Preprint","month":"03","volume":117,"issue":"12","related_material":{"link":[{"url":"https://ist.ac.at/en/news/proteins-as-molecular-switches/","description":"News on IST Homepage","relation":"press_release"}],"record":[{"status":"public","id":"8341","relation":"dissertation_contains"}]},"publication_status":"published","year":"2020","page":"6504-6549","pmid":1,"author":[{"id":"2A58201A-F248-11E8-B48F-1D18A9856A87","full_name":"Bezeljak, Urban","last_name":"Bezeljak","first_name":"Urban","orcid":"0000-0003-1365-5631"},{"last_name":"Loya","first_name":"Hrushikesh","full_name":"Loya, Hrushikesh"},{"full_name":"Kaczmarek, Beata M","id":"36FA4AFA-F248-11E8-B48F-1D18A9856A87","first_name":"Beata M","last_name":"Kaczmarek"},{"last_name":"Saunders","first_name":"Timothy E.","full_name":"Saunders, Timothy E."},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","full_name":"Loose, Martin","last_name":"Loose","first_name":"Martin","orcid":"0000-0001-7309-9724"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}]},{"publisher":"MDPI","file":[{"date_created":"2020-03-23T13:37:00Z","content_type":"application/pdf","relation":"main_file","creator":"dernst","access_level":"open_access","checksum":"6d5af3e17266a48996b4af4e67e88a85","date_updated":"2020-07-14T12:48:00Z","file_name":"2020_Plants_Moturu.pdf","file_id":"7614","file_size":2373484}],"isi":1,"doi":"10.3390/plants9030299","article_number":"299","date_published":"2020-03-01T00:00:00Z","_id":"7582","quality_controlled":"1","oa":1,"title":"Molecular evolution and diversification of proteins involved in miRNA maturation pathway","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","department":[{"_id":"JiFr"}],"day":"01","publication_identifier":{"eissn":["2223-7747"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"No","date_updated":"2026-04-02T14:35:47Z","ddc":["580"],"intvolume":"         9","project":[{"grant_number":"282300","_id":"25716A02-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Polarity and subcellular dynamics in plants"}],"abstract":[{"lang":"eng","text":"Small RNAs (smRNA, 19–25 nucleotides long), which are transcribed by RNA polymerase II, regulate the expression of genes involved in a multitude of processes in eukaryotes. miRNA biogenesis and the proteins involved in the biogenesis pathway differ across plant and animal lineages. The major proteins constituting the biogenesis pathway, namely, the Dicers (DCL/DCR) and Argonautes (AGOs), have been extensively studied. However, the accessory proteins (DAWDLE (DDL), SERRATE (SE), and TOUGH (TGH)) of the pathway that differs across the two lineages remain largely uncharacterized. We present the first detailed report on the molecular evolution and divergence of these proteins across eukaryotes. Although DDL is present in eukaryotes and prokaryotes, SE and TGH appear to be specific to eukaryotes. The addition/deletion of specific domains and/or domain-specific sequence divergence in the three proteins points to the observed functional divergence of these proteins across the two lineages, which correlates with the differences in miRNA length across the two lineages. Our data enhance the current understanding of the structure–function relationship of these proteins and reveals previous unexplored crucial residues in the three proteins that can be used as a basis for further functional characterization. The data presented here on the number of miRNAs in crown eukaryotic lineages are consistent with the notion of the expansion of the number of miRNA-coding genes in animal and plant lineages correlating with organismal complexity. Whether this difference in functionally correlates with the diversification (or presence/absence) of the three proteins studied here or the miRNA signaling in the plant and animal lineages is unclear. Based on our results of the three proteins studied here and previously available data concerning the evolution of miRNA genes in the plant and animal lineages, we believe that miRNAs probably evolved once in the ancestor to crown eukaryotes and have diversified independently in the eukaryotes."}],"has_accepted_license":"1","external_id":{"pmid":["32121542"],"isi":["000525315000035"]},"status":"public","publication":"Plants","scopus_import":"1","date_created":"2020-03-15T23:00:52Z","oa_version":"Published Version","type":"journal_article","corr_author":"1","article_type":"original","citation":{"mla":"Moturu, Taraka Ramji, et al. “Molecular Evolution and Diversification of Proteins Involved in MiRNA Maturation Pathway.” <i>Plants</i>, vol. 9, no. 3, 299, MDPI, 2020, doi:<a href=\"https://doi.org/10.3390/plants9030299\">10.3390/plants9030299</a>.","short":"T.R. Moturu, S. Sinha, H. Salava, S. Thula, T. Nodzyński, R.S. Vařeková, J. Friml, S. Simon, Plants 9 (2020).","apa":"Moturu, T. R., Sinha, S., Salava, H., Thula, S., Nodzyński, T., Vařeková, R. S., … Simon, S. (2020). Molecular evolution and diversification of proteins involved in miRNA maturation pathway. <i>Plants</i>. MDPI. <a href=\"https://doi.org/10.3390/plants9030299\">https://doi.org/10.3390/plants9030299</a>","ama":"Moturu TR, Sinha S, Salava H, et al. Molecular evolution and diversification of proteins involved in miRNA maturation pathway. <i>Plants</i>. 2020;9(3). doi:<a href=\"https://doi.org/10.3390/plants9030299\">10.3390/plants9030299</a>","ieee":"T. R. Moturu <i>et al.</i>, “Molecular evolution and diversification of proteins involved in miRNA maturation pathway,” <i>Plants</i>, vol. 9, no. 3. MDPI, 2020.","ista":"Moturu TR, Sinha S, Salava H, Thula S, Nodzyński T, Vařeková RS, Friml J, Simon S. 2020. Molecular evolution and diversification of proteins involved in miRNA maturation pathway. Plants. 9(3), 299.","chicago":"Moturu, Taraka Ramji, Sansrity Sinha, Hymavathi Salava, Sravankumar Thula, Tomasz Nodzyński, Radka Svobodová Vařeková, Jiří Friml, and Sibu Simon. “Molecular Evolution and Diversification of Proteins Involved in MiRNA Maturation Pathway.” <i>Plants</i>. MDPI, 2020. <a href=\"https://doi.org/10.3390/plants9030299\">https://doi.org/10.3390/plants9030299</a>."},"ec_funded":1,"language":[{"iso":"eng"}],"publication_status":"published","file_date_updated":"2020-07-14T12:48:00Z","year":"2020","month":"03","issue":"3","volume":9,"author":[{"full_name":"Moturu, Taraka Ramji","first_name":"Taraka Ramji","last_name":"Moturu"},{"full_name":"Sinha, Sansrity","first_name":"Sansrity","last_name":"Sinha"},{"full_name":"Salava, Hymavathi","last_name":"Salava","first_name":"Hymavathi"},{"full_name":"Thula, Sravankumar","first_name":"Sravankumar","last_name":"Thula"},{"full_name":"Nodzyński, Tomasz","first_name":"Tomasz","last_name":"Nodzyński"},{"full_name":"Vařeková, Radka Svobodová","first_name":"Radka Svobodová","last_name":"Vařeková"},{"last_name":"Friml","first_name":"Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří"},{"id":"4542EF9A-F248-11E8-B48F-1D18A9856A87","full_name":"Simon, Sibu","first_name":"Sibu","orcid":"0000-0002-1998-6741","last_name":"Simon"}],"pmid":1},{"intvolume":"        39","ddc":["570"],"date_updated":"2026-04-16T09:35:48Z","type":"journal_article","oa_version":"Published Version","scopus_import":"1","date_created":"2020-03-15T23:00:55Z","publication":"EMBO Journal","has_accepted_license":"1","external_id":{"isi":["000517335000001"],"pmid":["32118314"]},"status":"public","abstract":[{"lang":"eng","text":"CLC chloride/proton exchangers may support acidification of endolysosomes and raise their luminal Cl− concentration. Disruption of endosomal ClC‐3 causes severe neurodegeneration. To assess the importance of ClC‐3 Cl−/H+ exchange, we now generate Clcn3unc/unc mice in which ClC‐3 is converted into a Cl− channel. Unlike Clcn3−/− mice, Clcn3unc/unc mice appear normal owing to compensation by ClC‐4 with which ClC‐3 forms heteromers. ClC‐4 protein levels are strongly reduced in Clcn3−/−, but not in Clcn3unc/unc mice because ClC‐3unc binds and stabilizes ClC‐4 like wild‐type ClC‐3. Although mice lacking ClC‐4 appear healthy, its absence in Clcn3unc/unc/Clcn4−/− mice entails even stronger neurodegeneration than observed in Clcn3−/− mice. A fraction of ClC‐3 is found on synaptic vesicles, but miniature postsynaptic currents and synaptic vesicle acidification are not affected in Clcn3unc/unc or Clcn3−/− mice before neurodegeneration sets in. Both, Cl−/H+‐exchange activity and the stabilizing effect on ClC‐4, are central to the biological function of ClC‐3."}],"language":[{"iso":"eng"}],"article_type":"original","citation":{"apa":"Weinert, S., Gimber, N., Deuschel, D., Stuhlmann, T., Puchkov, D., Farsi, Z., … Jentsch, T. J. (2020). Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration. <i>EMBO Journal</i>. EMBO Press. <a href=\"https://doi.org/10.15252/embj.2019103358\">https://doi.org/10.15252/embj.2019103358</a>","ama":"Weinert S, Gimber N, Deuschel D, et al. Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration. <i>EMBO Journal</i>. 2020;39. doi:<a href=\"https://doi.org/10.15252/embj.2019103358\">10.15252/embj.2019103358</a>","ieee":"S. Weinert <i>et al.</i>, “Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration,” <i>EMBO Journal</i>, vol. 39. EMBO Press, 2020.","ista":"Weinert S, Gimber N, Deuschel D, Stuhlmann T, Puchkov D, Farsi Z, Ludwig CF, Novarino G, López-Cayuqueo KI, Planells-Cases R, Jentsch TJ. 2020. Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration. EMBO Journal. 39, e103358.","mla":"Weinert, Stefanie, et al. “Uncoupling Endosomal CLC Chloride/Proton Exchange Causes Severe Neurodegeneration.” <i>EMBO Journal</i>, vol. 39, e103358, EMBO Press, 2020, doi:<a href=\"https://doi.org/10.15252/embj.2019103358\">10.15252/embj.2019103358</a>.","short":"S. Weinert, N. Gimber, D. Deuschel, T. Stuhlmann, D. Puchkov, Z. Farsi, C.F. Ludwig, G. Novarino, K.I. López-Cayuqueo, R. Planells-Cases, T.J. Jentsch, EMBO Journal 39 (2020).","chicago":"Weinert, Stefanie, Niclas Gimber, Dorothea Deuschel, Till Stuhlmann, Dmytro Puchkov, Zohreh Farsi, Carmen F. Ludwig, et al. “Uncoupling Endosomal CLC Chloride/Proton Exchange Causes Severe Neurodegeneration.” <i>EMBO Journal</i>. EMBO Press, 2020. <a href=\"https://doi.org/10.15252/embj.2019103358\">https://doi.org/10.15252/embj.2019103358</a>."},"year":"2020","publication_status":"published","file_date_updated":"2020-07-14T12:48:00Z","volume":39,"month":"03","author":[{"full_name":"Weinert, Stefanie","last_name":"Weinert","first_name":"Stefanie"},{"first_name":"Niclas","last_name":"Gimber","full_name":"Gimber, Niclas"},{"full_name":"Deuschel, Dorothea","first_name":"Dorothea","last_name":"Deuschel"},{"full_name":"Stuhlmann, Till","last_name":"Stuhlmann","first_name":"Till"},{"full_name":"Puchkov, Dmytro","last_name":"Puchkov","first_name":"Dmytro"},{"last_name":"Farsi","first_name":"Zohreh","full_name":"Farsi, Zohreh"},{"full_name":"Ludwig, Carmen F.","last_name":"Ludwig","first_name":"Carmen F."},{"full_name":"Novarino, Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","last_name":"Novarino","orcid":"0000-0002-7673-7178","first_name":"Gaia"},{"full_name":"López-Cayuqueo, Karen I.","first_name":"Karen I.","last_name":"López-Cayuqueo"},{"first_name":"Rosa","last_name":"Planells-Cases","full_name":"Planells-Cases, Rosa"},{"first_name":"Thomas J.","last_name":"Jentsch","full_name":"Jentsch, Thomas J."}],"pmid":1,"doi":"10.15252/embj.2019103358","isi":1,"acknowledgement":"We thank T. Stauber and T. Breiderhoff for cloning expression constructs; K. Räbel, S. Hohensee, and C. Backhaus for technical assistance; R. Jahn (MPIbpc, Göttingen) for providing the equipment required for SV purification; and A\r\nWoehler (MDC, Berlin) for assistance with SV imaging. Supported, in part, by grants from the Deutsche Forschungsgemeinschaft (JE164/9-2, SFB740 TP C5, FOR 2625 (JE164/14-1), NeuroCure Cluster of Excellence), the European Research Council Advanced Grant CYTOVOLION (ERC 294435) and the Prix Louis-Jeantet de Médecine to TJJ, and Peter and Traudl Engelhorn fellowship to ZF.","file":[{"access_level":"open_access","relation":"main_file","creator":"dernst","date_created":"2020-03-23T13:51:11Z","content_type":"application/pdf","file_size":12243278,"date_updated":"2020-07-14T12:48:00Z","file_name":"2020_EMBO_Weinert.pdf","file_id":"7615","checksum":"82750a7a93e3740decbce8474004111a"}],"publisher":"EMBO Press","_id":"7586","quality_controlled":"1","date_published":"2020-03-02T00:00:00Z","article_number":"e103358","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration","oa":1,"day":"02","department":[{"_id":"GaNo"}],"article_processing_charge":"No","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"publication_identifier":{"eissn":["1460-2075"],"issn":["0261-4189"]}},{"date_created":"2020-03-20T13:16:41Z","oa_version":"Published Version","scopus_import":"1","publication":"eLife","type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/751958"}],"abstract":[{"lang":"eng","text":"Heterozygous loss of human PAFAH1B1 (coding for LIS1) results in the disruption of neurogenesis and neuronal migration via dysregulation of microtubule (MT) stability and dynein motor function/localization that alters mitotic spindle orientation, chromosomal segregation, and nuclear migration. Recently, human induced pluripotent stem cell (iPSC) models revealed an important role for LIS1 in controlling the length of terminal cell divisions of outer radial glial (oRG) progenitors, suggesting cellular functions of LIS1 in regulating neural progenitor cell (NPC) daughter cell separation. Here we examined the late mitotic stages NPCs in vivo and mouse embryonic fibroblasts (MEFs) in vitro from Pafah1b1-deficient mutants. Pafah1b1-deficient neocortical NPCs and MEFs similarly exhibited cleavage plane displacement with mislocalization of furrow-associated markers, associated with actomyosin dysfunction and cell membrane hyper-contractility. Thus, it suggests LIS1 acts as a key molecular link connecting MTs/dynein and actomyosin, ensuring that cell membrane contractility is tightly controlled to execute proper daughter cell separation."}],"status":"public","has_accepted_license":"1","external_id":{"pmid":["32159512"],"isi":["000522835800001"]},"citation":{"chicago":"Moon, Hyang Mi, Simon Hippenmeyer, Liqun Luo, and Anthony Wynshaw-Boris. “LIS1 Determines Cleavage Plane Positioning by Regulating Actomyosin-Mediated Cell Membrane Contractility.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/elife.51512\">https://doi.org/10.7554/elife.51512</a>.","short":"H.M. Moon, S. Hippenmeyer, L. Luo, A. Wynshaw-Boris, ELife 9 (2020).","mla":"Moon, Hyang Mi, et al. “LIS1 Determines Cleavage Plane Positioning by Regulating Actomyosin-Mediated Cell Membrane Contractility.” <i>ELife</i>, vol. 9, 51512, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/elife.51512\">10.7554/elife.51512</a>.","ista":"Moon HM, Hippenmeyer S, Luo L, Wynshaw-Boris A. 2020. LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility. eLife. 9, 51512.","ieee":"H. M. Moon, S. Hippenmeyer, L. Luo, and A. Wynshaw-Boris, “LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020.","ama":"Moon HM, Hippenmeyer S, Luo L, Wynshaw-Boris A. LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/elife.51512\">10.7554/elife.51512</a>","apa":"Moon, H. M., Hippenmeyer, S., Luo, L., &#38; Wynshaw-Boris, A. (2020). LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.51512\">https://doi.org/10.7554/elife.51512</a>"},"article_type":"original","language":[{"iso":"eng"}],"intvolume":"         9","date_updated":"2023-08-18T07:06:31Z","ddc":["570"],"author":[{"last_name":"Moon","first_name":"Hyang Mi","full_name":"Moon, Hyang Mi"},{"full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","first_name":"Simon","last_name":"Hippenmeyer"},{"first_name":"Liqun","last_name":"Luo","full_name":"Luo, Liqun"},{"full_name":"Wynshaw-Boris, Anthony","last_name":"Wynshaw-Boris","first_name":"Anthony"}],"pmid":1,"year":"2020","publication_status":"published","file_date_updated":"2020-09-24T07:03:20Z","volume":9,"month":"03","_id":"7593","date_published":"2020-03-11T00:00:00Z","quality_controlled":"1","article_number":"51512","file":[{"content_type":"application/pdf","date_created":"2020-09-24T07:03:20Z","access_level":"open_access","relation":"main_file","creator":"dernst","date_updated":"2020-09-24T07:03:20Z","file_name":"2020_elife_Moon.pdf","file_id":"8567","checksum":"396ceb2dd10b102ef4e699666b9342c3","success":1,"file_size":15089438}],"doi":"10.7554/elife.51512","isi":1,"publisher":"eLife Sciences Publications","article_processing_charge":"No","publication_identifier":{"issn":["2050-084X"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa":1,"title":"LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility","day":"11","department":[{"_id":"SiHi"}]},{"title":"How spin-orbital entanglement depends on the spin-orbit coupling in a Mott insulator","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"MiLe"}],"day":"20","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"No","publisher":"American Physical Society","doi":"10.1103/PhysRevResearch.2.013353","file":[{"date_updated":"2020-07-14T12:48:00Z","file_name":"2020_PhysRevResearch_Gotfryd.pdf","file_id":"7610","checksum":"1be551fd5f5583635076017d7391ffdc","file_size":1436735,"date_created":"2020-03-23T10:18:38Z","content_type":"application/pdf","access_level":"open_access","relation":"main_file","creator":"dernst"}],"article_number":"013353","quality_controlled":"1","_id":"7594","date_published":"2020-03-20T00:00:00Z","publication_status":"published","file_date_updated":"2020-07-14T12:48:00Z","year":"2020","month":"03","volume":2,"issue":"1","author":[{"first_name":"Dorota","last_name":"Gotfryd","full_name":"Gotfryd, Dorota"},{"id":"8275014E-6063-11E9-9B7F-6338E6697425","full_name":"Paerschke, Ekaterina","first_name":"Ekaterina","orcid":"0000-0003-0853-8182","last_name":"Paerschke"},{"full_name":"Chaloupka, Jiri","first_name":"Jiri","last_name":"Chaloupka"},{"first_name":"Andrzej M.","last_name":"Oles","full_name":"Oles, Andrzej M."},{"first_name":"Krzysztof","last_name":"Wohlfeld","full_name":"Wohlfeld, Krzysztof"}],"ddc":["530"],"date_updated":"2024-10-21T06:02:21Z","intvolume":"         2","project":[{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411"}],"has_accepted_license":"1","status":"public","abstract":[{"text":"The concept of the entanglement between spin and orbital degrees of freedom plays a crucial role in our understanding of various phases and exotic ground states in a broad class of materials, including orbitally ordered materials and spin liquids. We investigate how the spin-orbital entanglement in a Mott insulator depends on the value of the spin-orbit coupling of the relativistic origin. To this end, we numerically diagonalize a one-dimensional spin-orbital model with Kugel-Khomskii exchange interactions between spins and orbitals on different sites supplemented by the on-site spin-orbit coupling. In the regime of small spin-orbit coupling with regard to the spin-orbital exchange, the ground state to a large extent resembles the one obtained in the limit of vanishing spin-orbit coupling. On the other hand, for large spin-orbit coupling the ground state can, depending on the model parameters, either still show negligible spin-orbital entanglement or evolve to a highly spin-orbitally-entangled phase with completely distinct properties that are described by an effective XXZ model. The presented results suggest that (i) the spin-orbital entanglement may be induced by large on-site spin-orbit coupling, as found in the 5d transition metal oxides, such as the iridates; (ii) for Mott insulators with weak spin-orbit coupling of Ising type, such as, e.g., the alkali hyperoxides, the effects of the spin-orbit coupling on the ground state can, in the first order of perturbation theory, be neglected.","lang":"eng"}],"type":"journal_article","scopus_import":"1","publication":"Physical Review Research","date_created":"2020-03-20T15:21:10Z","oa_version":"Published Version","language":[{"iso":"eng"}],"ec_funded":1,"citation":{"ista":"Gotfryd D, Paerschke E, Chaloupka J, Oles AM, Wohlfeld K. 2020. How spin-orbital entanglement depends on the spin-orbit coupling in a Mott insulator. Physical Review Research. 2(1), 013353.","ama":"Gotfryd D, Paerschke E, Chaloupka J, Oles AM, Wohlfeld K. How spin-orbital entanglement depends on the spin-orbit coupling in a Mott insulator. <i>Physical Review Research</i>. 2020;2(1). doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.2.013353\">10.1103/PhysRevResearch.2.013353</a>","ieee":"D. Gotfryd, E. Paerschke, J. Chaloupka, A. M. Oles, and K. Wohlfeld, “How spin-orbital entanglement depends on the spin-orbit coupling in a Mott insulator,” <i>Physical Review Research</i>, vol. 2, no. 1. American Physical Society, 2020.","apa":"Gotfryd, D., Paerschke, E., Chaloupka, J., Oles, A. M., &#38; Wohlfeld, K. (2020). How spin-orbital entanglement depends on the spin-orbit coupling in a Mott insulator. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.2.013353\">https://doi.org/10.1103/PhysRevResearch.2.013353</a>","short":"D. Gotfryd, E. Paerschke, J. Chaloupka, A.M. Oles, K. Wohlfeld, Physical Review Research 2 (2020).","mla":"Gotfryd, Dorota, et al. “How Spin-Orbital Entanglement Depends on the Spin-Orbit Coupling in a Mott Insulator.” <i>Physical Review Research</i>, vol. 2, no. 1, 013353, American Physical Society, 2020, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.2.013353\">10.1103/PhysRevResearch.2.013353</a>.","chicago":"Gotfryd, Dorota, Ekaterina Paerschke, Jiri Chaloupka, Andrzej M. Oles, and Krzysztof Wohlfeld. “How Spin-Orbital Entanglement Depends on the Spin-Orbit Coupling in a Mott Insulator.” <i>Physical Review Research</i>. American Physical Society, 2020. <a href=\"https://doi.org/10.1103/PhysRevResearch.2.013353\">https://doi.org/10.1103/PhysRevResearch.2.013353</a>."},"article_type":"original"},{"project":[{"call_identifier":"H2020","_id":"261099A6-B435-11E9-9278-68D0E5697425","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","grant_number":"742985"},{"_id":"256FEF10-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanism underlying Salicylic Acid Regulation of Endocytic Trafficking in Arabidopsis","grant_number":"723-2015"}],"date_updated":"2026-04-02T11:50:26Z","intvolume":"         6","language":[{"iso":"eng"}],"citation":{"chicago":"Tan, Shutang, Xixi Zhang, Wei Kong, Xiao-Li Yang, Gergely Molnar, Zuzana Vondráková, Roberta Filepová, Jan Petrášek, Jiří Friml, and Hong-Wei Xue. “The Lipid Code-Dependent Phosphoswitch PDK1–D6PK Activates PIN-Mediated Auxin Efflux in Arabidopsis.” <i>Nature Plants</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41477-020-0648-9\">https://doi.org/10.1038/s41477-020-0648-9</a>.","ieee":"S. Tan <i>et al.</i>, “The lipid code-dependent phosphoswitch PDK1–D6PK activates PIN-mediated auxin efflux in Arabidopsis,” <i>Nature Plants</i>, vol. 6. Springer Nature, pp. 556–569, 2020.","ama":"Tan S, Zhang X, Kong W, et al. The lipid code-dependent phosphoswitch PDK1–D6PK activates PIN-mediated auxin efflux in Arabidopsis. <i>Nature Plants</i>. 2020;6:556-569. doi:<a href=\"https://doi.org/10.1038/s41477-020-0648-9\">10.1038/s41477-020-0648-9</a>","ista":"Tan S, Zhang X, Kong W, Yang X-L, Molnar G, Vondráková Z, Filepová R, Petrášek J, Friml J, Xue H-W. 2020. The lipid code-dependent phosphoswitch PDK1–D6PK activates PIN-mediated auxin efflux in Arabidopsis. Nature Plants. 6, 556–569.","apa":"Tan, S., Zhang, X., Kong, W., Yang, X.-L., Molnar, G., Vondráková, Z., … Xue, H.-W. (2020). The lipid code-dependent phosphoswitch PDK1–D6PK activates PIN-mediated auxin efflux in Arabidopsis. <i>Nature Plants</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41477-020-0648-9\">https://doi.org/10.1038/s41477-020-0648-9</a>","short":"S. Tan, X. Zhang, W. Kong, X.-L. Yang, G. Molnar, Z. Vondráková, R. Filepová, J. Petrášek, J. Friml, H.-W. Xue, Nature Plants 6 (2020) 556–569.","mla":"Tan, Shutang, et al. “The Lipid Code-Dependent Phosphoswitch PDK1–D6PK Activates PIN-Mediated Auxin Efflux in Arabidopsis.” <i>Nature Plants</i>, vol. 6, Springer Nature, 2020, pp. 556–69, doi:<a href=\"https://doi.org/10.1038/s41477-020-0648-9\">10.1038/s41477-020-0648-9</a>."},"ec_funded":1,"article_type":"original","status":"public","external_id":{"pmid":["32393881"],"isi":["000531787500006"]},"abstract":[{"text":"Directional intercellular transport of the phytohormone auxin mediated by PIN FORMED (PIN) efflux carriers plays essential roles in both coordinating patterning processes and integrating multiple external cues by rapidly redirecting auxin fluxes. Multilevel regulations of PIN activity under internal and external cues are complicated; however, the underlying molecular mechanism remains elusive. Here we demonstrate that 3’-Phosphoinositide-Dependent Protein Kinase1 (PDK1), which is conserved in plants and mammals, functions as a molecular hub integrating the upstream lipid signalling and the downstream substrate activity through phosphorylation. Genetic analysis uncovers that loss-of-function Arabidopsis mutant pdk1.1 pdk1.2 exhibits a plethora of abnormalities in organogenesis and growth, due to the defective PIN-dependent auxin transport. Further cellular and biochemical analyses reveal that PDK1 phosphorylates D6 Protein Kinase to facilitate its activity towards PIN proteins. Our studies establish a lipid-dependent phosphorylation cascade connecting membrane composition-based cellular signalling with plant growth and patterning by regulating morphogenetic auxin fluxes.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/755504"}],"type":"journal_article","oa_version":"Preprint","date_created":"2020-03-21T16:34:16Z","scopus_import":"1","publication":"Nature Plants","month":"05","volume":6,"related_material":{"link":[{"url":"https://doi.org/10.1038/s41477-020-0719-y","relation":"erratum"}]},"publication_status":"published","year":"2020","page":"556-569","pmid":1,"author":[{"full_name":"Tan, Shutang","id":"2DE75584-F248-11E8-B48F-1D18A9856A87","last_name":"Tan","orcid":"0000-0002-0471-8285","first_name":"Shutang"},{"full_name":"Zhang, Xixi","id":"61A66458-47E9-11EA-85BA-8AEAAF14E49A","orcid":"0000-0001-7048-4627","first_name":"Xixi","last_name":"Zhang"},{"full_name":"Kong, Wei","first_name":"Wei","last_name":"Kong"},{"full_name":"Yang, Xiao-Li","first_name":"Xiao-Li","last_name":"Yang"},{"first_name":"Gergely","last_name":"Molnar","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87","full_name":"Molnar, Gergely"},{"first_name":"Zuzana","last_name":"Vondráková","full_name":"Vondráková, Zuzana"},{"first_name":"Roberta","last_name":"Filepová","full_name":"Filepová, Roberta"},{"last_name":"Petrášek","first_name":"Jan","full_name":"Petrášek, Jan"},{"first_name":"Jiří","orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří"},{"last_name":"Xue","first_name":"Hong-Wei","full_name":"Xue, Hong-Wei"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"publisher":"Springer Nature","doi":"10.1038/s41477-020-0648-9","isi":1,"date_published":"2020-05-01T00:00:00Z","_id":"7600","quality_controlled":"1","department":[{"_id":"JiFr"}],"day":"01","title":"The lipid code-dependent phosphoswitch PDK1–D6PK activates PIN-mediated auxin efflux in Arabidopsis","oa":1,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publication_identifier":{"eissn":["2055-0278"]},"article_processing_charge":"No"},{"author":[{"full_name":"Nimeth, Barbara Anna","first_name":"Barbara Anna","last_name":"Nimeth"},{"orcid":"0000-0003-3413-1343","first_name":"Stefan","last_name":"Riegler","full_name":"Riegler, Stefan","id":"FF6018E0-D806-11E9-8E43-0B14E6697425"},{"last_name":"Kalyna","first_name":"Maria","full_name":"Kalyna, Maria"}],"year":"2020","publication_status":"published","file_date_updated":"2020-07-14T12:48:01Z","volume":11,"month":"02","type":"journal_article","oa_version":"Published Version","scopus_import":"1","date_created":"2020-03-22T23:00:46Z","publication":"Frontiers in Plant Science","has_accepted_license":"1","status":"public","external_id":{"isi":["000518903600001"]},"abstract":[{"text":"Plants are exposed to a variety of abiotic and biotic stresses that may result in DNA damage. Endogenous processes - such as DNA replication, DNA recombination, respiration, or photosynthesis - are also a threat to DNA integrity. It is therefore essential to understand the strategies plants have developed for DNA damage detection, signaling, and repair. Alternative splicing (AS) is a key post-transcriptional process with a role in regulation of gene expression. Recent studies demonstrate that the majority of intron-containing genes in plants are alternatively spliced, highlighting the importance of AS in plant development and stress response. Not only does AS ensure a versatile proteome and influence the abundance and availability of proteins greatly, it has also emerged as an important player in the DNA damage response (DDR) in animals. Despite extensive studies of DDR carried out in plants, its regulation at the level of AS has not been comprehensively addressed. Here, we provide some insights into the interplay between AS and DDR in plants.","lang":"eng"}],"language":[{"iso":"eng"}],"article_type":"original","citation":{"apa":"Nimeth, B. A., Riegler, S., &#38; Kalyna, M. (2020). Alternative splicing and DNA damage response in plants. <i>Frontiers in Plant Science</i>. Frontiers. <a href=\"https://doi.org/10.3389/fpls.2020.00091\">https://doi.org/10.3389/fpls.2020.00091</a>","ama":"Nimeth BA, Riegler S, Kalyna M. Alternative splicing and DNA damage response in plants. <i>Frontiers in Plant Science</i>. 2020;11. doi:<a href=\"https://doi.org/10.3389/fpls.2020.00091\">10.3389/fpls.2020.00091</a>","ista":"Nimeth BA, Riegler S, Kalyna M. 2020. Alternative splicing and DNA damage response in plants. Frontiers in Plant Science. 11, 91.","ieee":"B. A. Nimeth, S. Riegler, and M. Kalyna, “Alternative splicing and DNA damage response in plants,” <i>Frontiers in Plant Science</i>, vol. 11. Frontiers, 2020.","mla":"Nimeth, Barbara Anna, et al. “Alternative Splicing and DNA Damage Response in Plants.” <i>Frontiers in Plant Science</i>, vol. 11, 91, Frontiers, 2020, doi:<a href=\"https://doi.org/10.3389/fpls.2020.00091\">10.3389/fpls.2020.00091</a>.","short":"B.A. Nimeth, S. Riegler, M. Kalyna, Frontiers in Plant Science 11 (2020).","chicago":"Nimeth, Barbara Anna, Stefan Riegler, and Maria Kalyna. “Alternative Splicing and DNA Damage Response in Plants.” <i>Frontiers in Plant Science</i>. Frontiers, 2020. <a href=\"https://doi.org/10.3389/fpls.2020.00091\">https://doi.org/10.3389/fpls.2020.00091</a>."},"intvolume":"        11","ddc":["580"],"date_updated":"2026-04-16T08:28:17Z","article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["1664-462X"]},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Alternative splicing and DNA damage response in plants","oa":1,"day":"19","department":[{"_id":"FyKo"}],"date_published":"2020-02-19T00:00:00Z","_id":"7603","quality_controlled":"1","article_number":"91","isi":1,"file":[{"file_name":"2020_FrontiersPlants_Nimeth.pdf","file_id":"7607","date_updated":"2020-07-14T12:48:01Z","checksum":"57c37209f7b6712ced86c0f11b2be74e","file_size":507414,"content_type":"application/pdf","date_created":"2020-03-23T09:03:40Z","access_level":"open_access","creator":"dernst","relation":"main_file"}],"doi":"10.3389/fpls.2020.00091","publisher":"Frontiers"},{"_id":"7605","quality_controlled":"1","date_published":"2020-02-01T00:00:00Z","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","doi":"10.4230/LIPIcs.OPODIS.2019.15","file":[{"checksum":"d66f07ecb609d9f02433e39f80a447e9","file_name":"2019_LIPIcs_Alistarh.pdf","file_id":"7609","date_updated":"2020-07-14T12:48:01Z","file_size":13074131,"date_created":"2020-03-23T09:22:48Z","content_type":"application/pdf","creator":"dernst","relation":"main_file","access_level":"open_access"}],"conference":{"end_date":"2019-12-19","start_date":"2019-12-17","location":"Neuchatal, Switzerland","name":"OPODIS: International Conference on Principles of Distributed Systems"},"publication_identifier":{"isbn":["9783959771337"],"issn":["1868-8969"]},"tmp":{"name":"Creative Commons Attribution 3.0 Unported (CC BY 3.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/3.0/legalcode","short":"CC BY (3.0)"},"article_processing_charge":"No","department":[{"_id":"DaAl"}],"day":"01","oa":1,"title":"In search of the fastest concurrent union-find algorithm","license":"https://creativecommons.org/licenses/by/3.0/","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Alistarh, Dan-Adrian, et al. “In Search of the Fastest Concurrent Union-Find Algorithm.” <i>23rd International Conference on Principles of Distributed Systems</i>, vol. 153, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020, p. 15:1-15:16, doi:<a href=\"https://doi.org/10.4230/LIPIcs.OPODIS.2019.15\">10.4230/LIPIcs.OPODIS.2019.15</a>.","short":"D.-A. Alistarh, A. Fedorov, N. Koval, in:, 23rd International Conference on Principles of Distributed Systems, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020, p. 15:1-15:16.","apa":"Alistarh, D.-A., Fedorov, A., &#38; Koval, N. (2020). In search of the fastest concurrent union-find algorithm. In <i>23rd International Conference on Principles of Distributed Systems</i> (Vol. 153, p. 15:1-15:16). Neuchatal, Switzerland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.OPODIS.2019.15\">https://doi.org/10.4230/LIPIcs.OPODIS.2019.15</a>","ista":"Alistarh D-A, Fedorov A, Koval N. 2020. In search of the fastest concurrent union-find algorithm. 23rd International Conference on Principles of Distributed Systems. OPODIS: International Conference on Principles of Distributed Systems, LIPIcs, vol. 153, 15:1-15:16.","ieee":"D.-A. Alistarh, A. Fedorov, and N. Koval, “In search of the fastest concurrent union-find algorithm,” in <i>23rd International Conference on Principles of Distributed Systems</i>, Neuchatal, Switzerland, 2020, vol. 153, p. 15:1-15:16.","ama":"Alistarh D-A, Fedorov A, Koval N. In search of the fastest concurrent union-find algorithm. In: <i>23rd International Conference on Principles of Distributed Systems</i>. Vol 153. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2020:15:1-15:16. doi:<a href=\"https://doi.org/10.4230/LIPIcs.OPODIS.2019.15\">10.4230/LIPIcs.OPODIS.2019.15</a>","chicago":"Alistarh, Dan-Adrian, Alexander Fedorov, and Nikita Koval. “In Search of the Fastest Concurrent Union-Find Algorithm.” In <i>23rd International Conference on Principles of Distributed Systems</i>, 153:15:1-15:16. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020. <a href=\"https://doi.org/10.4230/LIPIcs.OPODIS.2019.15\">https://doi.org/10.4230/LIPIcs.OPODIS.2019.15</a>."},"language":[{"iso":"eng"}],"abstract":[{"text":"Union-Find (or Disjoint-Set Union) is one of the fundamental problems in computer science; it has been well-studied from both theoretical and practical perspectives in the sequential case. Recently, there has been mounting interest in analyzing this problem in the concurrent scenario, and several asymptotically-efficient algorithms have been proposed. Yet, to date, there is very little known about the practical performance of concurrent Union-Find. This work addresses this gap. We evaluate and analyze the performance of several concurrent Union-Find algorithms and optimization strategies across a wide range of platforms (Intel, AMD, and ARM) and workloads (social, random, and road networks, as well as integrations into more complex algorithms). We first observe that, due to the limited computational cost, the number of induced cache misses is the critical determining factor for the performance of existing algorithms. We introduce new techniques to reduce this cost by storing node priorities implicitly and by using plain reads and writes in a way that does not affect the correctness of the algorithms. Finally, we show that Union-Find implementations are an interesting application for Transactional Memory (TM): one of the fastest algorithm variants we discovered is a sequential one that uses coarse-grained locking with the lock elision optimization to reduce synchronization cost and increase scalability. ","lang":"eng"}],"external_id":{"arxiv":["1911.06347"]},"status":"public","has_accepted_license":"1","date_created":"2020-03-22T23:00:46Z","publication":"23rd International Conference on Principles of Distributed Systems","scopus_import":"1","oa_version":"Published Version","type":"conference","corr_author":"1","date_updated":"2025-07-10T11:54:46Z","arxiv":1,"ddc":["000"],"intvolume":"       153","page":"15:1-15:16","author":[{"last_name":"Alistarh","first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","full_name":"Alistarh, Dan-Adrian"},{"full_name":"Fedorov, Alexander","last_name":"Fedorov","first_name":"Alexander"},{"full_name":"Koval, Nikita","id":"2F4DB10C-F248-11E8-B48F-1D18A9856A87","last_name":"Koval","first_name":"Nikita"}],"alternative_title":["LIPIcs"],"month":"02","volume":153,"file_date_updated":"2020-07-14T12:48:01Z","publication_status":"published","year":"2020"},{"language":[{"iso":"eng"}],"article_type":"original","citation":{"mla":"Rademacher, Simone Anna Elvira. “Central Limit Theorem for Bose Gases Interacting through Singular Potentials.” <i>Letters in Mathematical Physics</i>, vol. 110, Springer Nature, 2020, pp. 2143–74, doi:<a href=\"https://doi.org/10.1007/s11005-020-01286-w\">10.1007/s11005-020-01286-w</a>.","short":"S.A.E. Rademacher, Letters in Mathematical Physics 110 (2020) 2143–2174.","apa":"Rademacher, S. A. E. (2020). Central limit theorem for Bose gases interacting through singular potentials. <i>Letters in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11005-020-01286-w\">https://doi.org/10.1007/s11005-020-01286-w</a>","ista":"Rademacher SAE. 2020. Central limit theorem for Bose gases interacting through singular potentials. Letters in Mathematical Physics. 110, 2143–2174.","ieee":"S. A. E. Rademacher, “Central limit theorem for Bose gases interacting through singular potentials,” <i>Letters in Mathematical Physics</i>, vol. 110. Springer Nature, pp. 2143–2174, 2020.","ama":"Rademacher SAE. Central limit theorem for Bose gases interacting through singular potentials. <i>Letters in Mathematical Physics</i>. 2020;110:2143-2174. doi:<a href=\"https://doi.org/10.1007/s11005-020-01286-w\">10.1007/s11005-020-01286-w</a>","chicago":"Rademacher, Simone Anna Elvira. “Central Limit Theorem for Bose Gases Interacting through Singular Potentials.” <i>Letters in Mathematical Physics</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s11005-020-01286-w\">https://doi.org/10.1007/s11005-020-01286-w</a>."},"ec_funded":1,"external_id":{"isi":["000551556000006"]},"status":"public","has_accepted_license":"1","abstract":[{"text":"We consider a system of N bosons in the limit N→∞, interacting through singular potentials. For initial data exhibiting Bose–Einstein condensation, the many-body time evolution is well approximated through a quadratic fluctuation dynamics around a cubic nonlinear Schrödinger equation of the condensate wave function. We show that these fluctuations satisfy a (multi-variate) central limit theorem.","lang":"eng"}],"type":"journal_article","corr_author":"1","publication":"Letters in Mathematical Physics","scopus_import":"1","oa_version":"Published Version","date_created":"2020-03-23T11:11:47Z","project":[{"call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411"},{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"}],"ddc":["510"],"date_updated":"2025-04-14T07:44:03Z","intvolume":"       110","page":"2143-2174","author":[{"first_name":"Simone Anna Elvira","orcid":"0000-0001-5059-4466","last_name":"Rademacher","id":"856966FE-A408-11E9-977E-802DE6697425","full_name":"Rademacher, Simone Anna Elvira"}],"month":"03","volume":110,"file_date_updated":"2020-11-20T12:04:26Z","publication_status":"published","year":"2020","_id":"7611","date_published":"2020-03-12T00:00:00Z","quality_controlled":"1","publisher":"Springer Nature","file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_created":"2020-11-20T12:04:26Z","content_type":"application/pdf","file_size":478683,"success":1,"checksum":"3bdd41f10ad947b67a45b98f507a7d4a","date_updated":"2020-11-20T12:04:26Z","file_name":"2020_LettersMathPhysics_Rademacher.pdf","file_id":"8784"}],"isi":1,"acknowledgement":"Simone Rademacher acknowledges partial support from the NCCR SwissMAP. This project has received\r\nfunding from the European Union’s Horizon 2020 research and innovation program under the Marie\r\nSkłodowska-Curie Grant Agreement No. 754411.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria).\r\nS.R. would like to thank Benjamin Schlein for many fruitful discussions.","doi":"10.1007/s11005-020-01286-w","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["1573-0530"],"issn":["0377-9017"]},"article_processing_charge":"Yes (via OA deal)","department":[{"_id":"RoSe"}],"day":"12","title":"Central limit theorem for Bose gases interacting through singular potentials","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1"}]