[{"quality_controlled":"1","_id":"7650","date_published":"2020-03-09T00:00:00Z","publisher":"Springer Nature","doi":"10.1007/s00205-020-01489-4","file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_created":"2020-11-20T13:17:42Z","content_type":"application/pdf","file_size":704633,"checksum":"b645fb64bfe95bbc05b3eea374109a9c","success":1,"date_updated":"2020-11-20T13:17:42Z","file_id":"8785","file_name":"2020_ArchRatMechanicsAnalysis_Deuchert.pdf"}],"acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). It is a pleasure to thank Jakob Yngvason for helpful discussions. Financial support by the European Research Council (ERC) under the European Union’sHorizon 2020 research and innovation programme (Grant Agreement No. 694227) is gratefully acknowledged. A. D. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 836146.","isi":1,"publication_identifier":{"issn":["0003-9527"],"eissn":["1432-0673"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","oa":1,"title":"Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","department":[{"_id":"RoSe"}],"day":"09","abstract":[{"lang":"eng","text":"We consider a dilute, homogeneous Bose gas at positive temperature. The system is investigated in the Gross–Pitaevskii limit, where the scattering length a is so small that the interaction energy is of the same order of magnitude as the spectral gap of the Laplacian, and for temperatures that are comparable to the critical temperature of the ideal gas. We show that the difference between the specific free energy of the interacting system and the one of the ideal gas is to leading order given by 4πa(2ϱ2−ϱ20). Here ϱ denotes the density of the system and ϱ0 is the expected condensate density of the ideal gas. Additionally, we show that the one-particle density matrix of any approximate minimizer of the Gibbs free energy functional is to leading order given by the one of the ideal gas. This in particular proves Bose–Einstein condensation with critical temperature given by the one of the ideal gas to leading order. One key ingredient of our proof is a novel use of the Gibbs variational principle that goes hand in hand with the c-number substitution."}],"external_id":{"isi":["000519415000001"],"arxiv":["1901.11363"]},"has_accepted_license":"1","status":"public","scopus_import":"1","date_created":"2020-04-08T15:18:03Z","publication":"Archive for Rational Mechanics and Analysis","oa_version":"Published Version","corr_author":"1","type":"journal_article","ec_funded":1,"citation":{"chicago":"Deuchert, Andreas, and Robert Seiringer. “Gross-Pitaevskii Limit of a Homogeneous Bose Gas at Positive Temperature.” <i>Archive for Rational Mechanics and Analysis</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00205-020-01489-4\">https://doi.org/10.1007/s00205-020-01489-4</a>.","short":"A. Deuchert, R. Seiringer, Archive for Rational Mechanics and Analysis 236 (2020) 1217–1271.","mla":"Deuchert, Andreas, and Robert Seiringer. “Gross-Pitaevskii Limit of a Homogeneous Bose Gas at Positive Temperature.” <i>Archive for Rational Mechanics and Analysis</i>, vol. 236, no. 6, Springer Nature, 2020, pp. 1217–71, doi:<a href=\"https://doi.org/10.1007/s00205-020-01489-4\">10.1007/s00205-020-01489-4</a>.","ista":"Deuchert A, Seiringer R. 2020. Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature. Archive for Rational Mechanics and Analysis. 236(6), 1217–1271.","ieee":"A. Deuchert and R. Seiringer, “Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature,” <i>Archive for Rational Mechanics and Analysis</i>, vol. 236, no. 6. Springer Nature, pp. 1217–1271, 2020.","ama":"Deuchert A, Seiringer R. Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature. <i>Archive for Rational Mechanics and Analysis</i>. 2020;236(6):1217-1271. doi:<a href=\"https://doi.org/10.1007/s00205-020-01489-4\">10.1007/s00205-020-01489-4</a>","apa":"Deuchert, A., &#38; Seiringer, R. (2020). Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature. <i>Archive for Rational Mechanics and Analysis</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00205-020-01489-4\">https://doi.org/10.1007/s00205-020-01489-4</a>"},"article_type":"original","language":[{"iso":"eng"}],"date_updated":"2025-04-14T07:27:00Z","arxiv":1,"ddc":["510"],"intvolume":"       236","project":[{"grant_number":"694227","call_identifier":"H2020","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems"},{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"}],"author":[{"id":"4DA65CD0-F248-11E8-B48F-1D18A9856A87","full_name":"Deuchert, Andreas","first_name":"Andreas","orcid":"0000-0003-3146-6746","last_name":"Deuchert"},{"orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer","full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}],"page":"1217-1271","publication_status":"published","file_date_updated":"2020-11-20T13:17:42Z","year":"2020","month":"03","issue":"6","volume":236},{"date_published":"2020-03-13T00:00:00Z","_id":"7656","quality_controlled":"1","article_number":"20","isi":1,"doi":"10.3389/fncom.2020.00020","file":[{"access_level":"open_access","relation":"main_file","creator":"dernst","content_type":"application/pdf","date_created":"2020-04-14T12:20:39Z","file_size":4082937,"date_updated":"2020-07-14T12:48:01Z","file_id":"7659","file_name":"2020_Frontiers_Berry.pdf","checksum":"2b1da23823eae9cedbb42d701945b61e"}],"publisher":"Frontiers","article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["1662-5188"]},"day":"13","department":[{"_id":"GaTk"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Clustering of neural activity: A design principle for population codes","oa":1,"language":[{"iso":"eng"}],"article_type":"original","citation":{"chicago":"Berry, Michael J., and Gašper Tkačik. “Clustering of Neural Activity: A Design Principle for Population Codes.” <i>Frontiers in Computational Neuroscience</i>. Frontiers, 2020. <a href=\"https://doi.org/10.3389/fncom.2020.00020\">https://doi.org/10.3389/fncom.2020.00020</a>.","mla":"Berry, Michael J., and Gašper Tkačik. “Clustering of Neural Activity: A Design Principle for Population Codes.” <i>Frontiers in Computational Neuroscience</i>, vol. 14, 20, Frontiers, 2020, doi:<a href=\"https://doi.org/10.3389/fncom.2020.00020\">10.3389/fncom.2020.00020</a>.","short":"M.J. Berry, G. Tkačik, Frontiers in Computational Neuroscience 14 (2020).","apa":"Berry, M. J., &#38; Tkačik, G. (2020). Clustering of neural activity: A design principle for population codes. <i>Frontiers in Computational Neuroscience</i>. Frontiers. <a href=\"https://doi.org/10.3389/fncom.2020.00020\">https://doi.org/10.3389/fncom.2020.00020</a>","ieee":"M. J. Berry and G. Tkačik, “Clustering of neural activity: A design principle for population codes,” <i>Frontiers in Computational Neuroscience</i>, vol. 14. Frontiers, 2020.","ista":"Berry MJ, Tkačik G. 2020. Clustering of neural activity: A design principle for population codes. Frontiers in Computational Neuroscience. 14, 20.","ama":"Berry MJ, Tkačik G. Clustering of neural activity: A design principle for population codes. <i>Frontiers in Computational Neuroscience</i>. 2020;14. doi:<a href=\"https://doi.org/10.3389/fncom.2020.00020\">10.3389/fncom.2020.00020</a>"},"type":"journal_article","date_created":"2020-04-12T22:00:40Z","oa_version":"Published Version","scopus_import":"1","publication":"Frontiers in Computational Neuroscience","has_accepted_license":"1","status":"public","external_id":{"isi":["000525543200001"],"pmid":["32231528"]},"abstract":[{"text":"We propose that correlations among neurons are generically strong enough to organize neural activity patterns into a discrete set of clusters, which can each be viewed as a population codeword. Our reasoning starts with the analysis of retinal ganglion cell data using maximum entropy models, showing that the population is robustly in a frustrated, marginally sub-critical, or glassy, state. This leads to an argument that neural populations in many other brain areas might share this structure. Next, we use latent variable models to show that this glassy state possesses well-defined clusters of neural activity. Clusters have three appealing properties: (i) clusters exhibit error correction, i.e., they are reproducibly elicited by the same stimulus despite variability at the level of constituent neurons; (ii) clusters encode qualitatively different visual features than their constituent neurons; and (iii) clusters can be learned by downstream neural circuits in an unsupervised fashion. We hypothesize that these properties give rise to a “learnable” neural code which the cortical hierarchy uses to extract increasingly complex features without supervision or reinforcement.","lang":"eng"}],"intvolume":"        14","ddc":["570"],"date_updated":"2026-04-16T08:28:50Z","pmid":1,"author":[{"first_name":"Michael J.","last_name":"Berry","full_name":"Berry, Michael J."},{"last_name":"Tkačik","first_name":"Gašper","orcid":"0000-0002-6699-1455","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","full_name":"Tkačik, Gašper"}],"volume":14,"month":"03","year":"2020","publication_status":"published","file_date_updated":"2020-07-14T12:48:01Z"},{"doi":"10.1021/acs.nanolett.0c00205","file":[{"file_size":7108014,"file_name":"2020_NanoLetters_Felhofer.pdf","file_id":"7667","date_updated":"2020-07-14T12:48:01Z","checksum":"fe46146a9c4c620592a1932a8599069e","access_level":"open_access","creator":"dernst","relation":"main_file","date_created":"2020-04-20T10:43:36Z","content_type":"application/pdf"}],"isi":1,"publisher":"American Chemical Society","_id":"7663","date_published":"2020-04-08T00:00:00Z","quality_controlled":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"title":"Wood deformation leads to rearrangement of molecules at the nanoscale","day":"08","department":[{"_id":"MaLo"}],"article_processing_charge":"No","publication_identifier":{"eissn":["1530-6992"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"intvolume":"        20","date_updated":"2026-04-02T14:26:44Z","ddc":["530"],"scopus_import":"1","date_created":"2020-04-19T22:00:54Z","publication":"Nano Letters","oa_version":"Published Version","type":"journal_article","abstract":[{"text":"Wood, as the most abundant carbon dioxide storing bioresource, is currently driven beyond its traditional use through creative innovations and nanotechnology. For many properties the micro- and nanostructure plays a crucial role and one key challenge is control and detection of chemical and physical processes in the confined microstructure and nanopores of the wooden cell wall. In this study, correlative Raman and atomic force microscopy show high potential for tracking in situ molecular rearrangement of wood polymers during compression. More water molecules (interpreted as wider cellulose microfibril distances) and disentangling of hemicellulose chains are detected in the opened cell wall regions, whereas an increase of lignin is revealed in the compressed areas. These results support a new more “loose” cell wall model based on flexible lignin nanodomains and advance our knowledge of the molecular reorganization during deformation of wood for optimized processing and utilization.","lang":"eng"}],"status":"public","external_id":{"pmid":["32196350"],"isi":["000526413400055"]},"has_accepted_license":"1","citation":{"chicago":"Felhofer, Martin, Peter Bock, Adya Singh, Batirtze Prats Mateu, Ronald Zirbs, and Notburga Gierlinger. “Wood Deformation Leads to Rearrangement of Molecules at the Nanoscale.” <i>Nano Letters</i>. American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/acs.nanolett.0c00205\">https://doi.org/10.1021/acs.nanolett.0c00205</a>.","apa":"Felhofer, M., Bock, P., Singh, A., Prats Mateu, B., Zirbs, R., &#38; Gierlinger, N. (2020). Wood deformation leads to rearrangement of molecules at the nanoscale. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.0c00205\">https://doi.org/10.1021/acs.nanolett.0c00205</a>","ista":"Felhofer M, Bock P, Singh A, Prats Mateu B, Zirbs R, Gierlinger N. 2020. Wood deformation leads to rearrangement of molecules at the nanoscale. Nano Letters. 20(4), 2647–2653.","ieee":"M. Felhofer, P. Bock, A. Singh, B. Prats Mateu, R. Zirbs, and N. Gierlinger, “Wood deformation leads to rearrangement of molecules at the nanoscale,” <i>Nano Letters</i>, vol. 20, no. 4. American Chemical Society, pp. 2647–2653, 2020.","ama":"Felhofer M, Bock P, Singh A, Prats Mateu B, Zirbs R, Gierlinger N. Wood deformation leads to rearrangement of molecules at the nanoscale. <i>Nano Letters</i>. 2020;20(4):2647-2653. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c00205\">10.1021/acs.nanolett.0c00205</a>","mla":"Felhofer, Martin, et al. “Wood Deformation Leads to Rearrangement of Molecules at the Nanoscale.” <i>Nano Letters</i>, vol. 20, no. 4, American Chemical Society, 2020, pp. 2647–53, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.0c00205\">10.1021/acs.nanolett.0c00205</a>.","short":"M. Felhofer, P. Bock, A. Singh, B. Prats Mateu, R. Zirbs, N. Gierlinger, Nano Letters 20 (2020) 2647–2653."},"article_type":"original","language":[{"iso":"eng"}],"year":"2020","file_date_updated":"2020-07-14T12:48:01Z","publication_status":"published","issue":"4","volume":20,"month":"04","author":[{"full_name":"Felhofer, Martin","first_name":"Martin","last_name":"Felhofer"},{"last_name":"Bock","first_name":"Peter","full_name":"Bock, Peter"},{"last_name":"Singh","first_name":"Adya","full_name":"Singh, Adya"},{"full_name":"Prats Mateu, Batirtze","id":"299FE892-F248-11E8-B48F-1D18A9856A87","first_name":"Batirtze","last_name":"Prats Mateu"},{"first_name":"Ronald","last_name":"Zirbs","full_name":"Zirbs, Ronald"},{"first_name":"Notburga","last_name":"Gierlinger","full_name":"Gierlinger, Notburga"}],"pmid":1,"page":"2647-2653"},{"file_date_updated":"2020-07-14T12:48:01Z","publication_status":"published","year":"2020","month":"04","issue":"7","volume":21,"author":[{"last_name":"Martín-Belmonte","first_name":"Alejandro","full_name":"Martín-Belmonte, Alejandro"},{"full_name":"Aguado, Carolina","first_name":"Carolina","last_name":"Aguado"},{"full_name":"Alfaro-Ruíz, Rocío","first_name":"Rocío","last_name":"Alfaro-Ruíz"},{"first_name":"Ana Esther","last_name":"Moreno-Martínez","full_name":"Moreno-Martínez, Ana Esther"},{"last_name":"De La Ossa","first_name":"Luis","full_name":"De La Ossa, Luis"},{"full_name":"Martínez-Hernández, José","last_name":"Martínez-Hernández","first_name":"José"},{"full_name":"Buisson, Alain","first_name":"Alain","last_name":"Buisson"},{"last_name":"Shigemoto","orcid":"0000-0001-8761-9444","first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Fukazawa","first_name":"Yugo","full_name":"Fukazawa, Yugo"},{"full_name":"Luján, Rafael","last_name":"Luján","first_name":"Rafael"}],"pmid":1,"date_updated":"2026-04-02T14:27:06Z","ddc":["570"],"intvolume":"        21","abstract":[{"text":"Metabotropic γ-aminobutyric acid (GABAB) receptors contribute to the control of network activity and information processing in hippocampal circuits by regulating neuronal excitability and synaptic transmission. The dysfunction in the dentate gyrus (DG) has been implicated in Alzheimer´s disease (AD). Given the involvement of GABAB receptors in AD, to determine their subcellular localisation and possible alteration in granule cells of the DG in a mouse model of AD at 12 months of age, we used high-resolution immunoelectron microscopic analysis. Immunohistochemistry at the light microscopic level showed that the regional and cellular expression pattern of GABAB1 was similar in an AD model mouse expressing mutated human amyloid precursor protein and presenilin1 (APP/PS1) and in age-matched wild type mice. High-resolution immunoelectron microscopy revealed a distance-dependent gradient of immunolabelling for GABAB receptors, increasing from proximal to distal dendrites in both wild type and APP/PS1 mice. However, the overall density of GABAB receptors at the neuronal surface of these postsynaptic compartments of granule cells was significantly reduced in APP/PS1 mice. Parallel to this reduction in surface receptors, we found a significant increase in GABAB1 at cytoplasmic sites. GABAB receptors were also detected at presynaptic sites in the molecular layer of the DG. We also found a decrease in plasma membrane GABAB receptors in axon terminals contacting dendritic spines of granule cells, which was more pronounced in the outer than in the inner molecular layer. Altogether, our data showing post- and presynaptic reduction in surface GABAB receptors in the DG suggest the alteration of the GABAB-mediated modulation of excitability and synaptic transmission in granule cells, which may contribute to the cognitive dysfunctions in the APP/PS1 model of AD","lang":"eng"}],"has_accepted_license":"1","status":"public","external_id":{"isi":["000535574200201"],"pmid":["32252271"]},"scopus_import":"1","date_created":"2020-04-19T22:00:55Z","oa_version":"Published Version","publication":"International journal of molecular sciences","type":"journal_article","citation":{"chicago":"Martín-Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro-Ruíz, Ana Esther Moreno-Martínez, Luis De La Ossa, José Martínez-Hernández, Alain Buisson, Ryuichi Shigemoto, Yugo Fukazawa, and Rafael Luján. “Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease.” <i>International Journal of Molecular Sciences</i>. MDPI, 2020. <a href=\"https://doi.org/10.3390/ijms21072459\">https://doi.org/10.3390/ijms21072459</a>.","short":"A. Martín-Belmonte, C. Aguado, R. Alfaro-Ruíz, A.E. Moreno-Martínez, L. De La Ossa, J. Martínez-Hernández, A. Buisson, R. Shigemoto, Y. Fukazawa, R. Luján, International Journal of Molecular Sciences 21 (2020).","mla":"Martín-Belmonte, Alejandro, et al. “Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease.” <i>International Journal of Molecular Sciences</i>, vol. 21, no. 7, 2459, MDPI, 2020, doi:<a href=\"https://doi.org/10.3390/ijms21072459\">10.3390/ijms21072459</a>.","ama":"Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, et al. Density of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s disease. <i>International journal of molecular sciences</i>. 2020;21(7). doi:<a href=\"https://doi.org/10.3390/ijms21072459\">10.3390/ijms21072459</a>","ieee":"A. Martín-Belmonte <i>et al.</i>, “Density of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s disease,” <i>International journal of molecular sciences</i>, vol. 21, no. 7. MDPI, 2020.","ista":"Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, Moreno-Martínez AE, De La Ossa L, Martínez-Hernández J, Buisson A, Shigemoto R, Fukazawa Y, Luján R. 2020. Density of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s disease. International journal of molecular sciences. 21(7), 2459.","apa":"Martín-Belmonte, A., Aguado, C., Alfaro-Ruíz, R., Moreno-Martínez, A. E., De La Ossa, L., Martínez-Hernández, J., … Luján, R. (2020). Density of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s disease. <i>International Journal of Molecular Sciences</i>. MDPI. <a href=\"https://doi.org/10.3390/ijms21072459\">https://doi.org/10.3390/ijms21072459</a>"},"article_type":"original","language":[{"iso":"eng"}],"oa":1,"title":"Density of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model of Alzheimer's disease","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","department":[{"_id":"RySh"}],"day":"02","publication_identifier":{"eissn":["1422-0067"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"No","publisher":"MDPI","isi":1,"doi":"10.3390/ijms21072459","file":[{"file_size":2941197,"checksum":"b9d2f1657d8c4a74b01a62b474d009b0","date_updated":"2020-07-14T12:48:01Z","file_name":"2020_JournMolecSciences_Martin_Belmonte.pdf","file_id":"7669","relation":"main_file","creator":"dernst","access_level":"open_access","content_type":"application/pdf","date_created":"2020-04-20T11:43:18Z"}],"article_number":"2459","quality_controlled":"1","_id":"7664","date_published":"2020-04-02T00:00:00Z"},{"pmid":1,"author":[{"last_name":"Eguchi","first_name":"Kohgaku","orcid":"0000-0002-6170-2546","id":"2B7846DC-F248-11E8-B48F-1D18A9856A87","full_name":"Eguchi, Kohgaku"},{"full_name":"Velicky, Philipp","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2340-7431","first_name":"Philipp","last_name":"Velicky"},{"id":"3C054040-F248-11E8-B48F-1D18A9856A87","full_name":"Hollergschwandtner, Elena","first_name":"Elena","last_name":"Hollergschwandtner"},{"first_name":"Makoto","last_name":"Itakura","full_name":"Itakura, Makoto"},{"last_name":"Fukazawa","first_name":"Yugo","full_name":"Fukazawa, Yugo"},{"orcid":"0000-0001-8559-3973","first_name":"Johann G","last_name":"Danzl","full_name":"Danzl, Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","first_name":"Ryuichi","last_name":"Shigemoto"}],"month":"03","volume":14,"file_date_updated":"2020-07-14T12:48:01Z","publication_status":"published","year":"2020","ec_funded":1,"citation":{"mla":"Eguchi, Kohgaku, et al. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>, vol. 14, 63, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>.","short":"K. Eguchi, P. Velicky, E. Saeckl, M. Itakura, Y. Fukazawa, J.G. Danzl, R. Shigemoto, Frontiers in Cellular Neuroscience 14 (2020).","apa":"Eguchi, K., Velicky, P., Saeckl, E., Itakura, M., Fukazawa, Y., Danzl, J. G., &#38; Shigemoto, R. (2020). Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>","ama":"Eguchi K, Velicky P, Saeckl E, et al. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. <i>Frontiers in Cellular Neuroscience</i>. 2020;14. doi:<a href=\"https://doi.org/10.3389/fncel.2020.00063\">10.3389/fncel.2020.00063</a>","ista":"Eguchi K, Velicky P, Saeckl E, Itakura M, Fukazawa Y, Danzl JG, Shigemoto R. 2020. Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions. Frontiers in Cellular Neuroscience. 14, 63.","ieee":"K. Eguchi <i>et al.</i>, “Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions,” <i>Frontiers in Cellular Neuroscience</i>, vol. 14. Frontiers Media, 2020.","chicago":"Eguchi, Kohgaku, Philipp Velicky, Elena Saeckl, Makoto Itakura, Yugo Fukazawa, Johann G Danzl, and Ryuichi Shigemoto. “Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular Neuroscience</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/fncel.2020.00063\">https://doi.org/10.3389/fncel.2020.00063</a>."},"article_type":"original","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Acute brain slice preparation is a powerful experimental model for investigating the characteristics of synaptic function in the brain. Although brain tissue is usually cut at ice-cold temperature (CT) to facilitate slicing and avoid neuronal damage, exposure to CT causes molecular and architectural changes of synapses. To address these issues, we investigated ultrastructural and electrophysiological features of synapses in mouse acute cerebellar slices prepared at ice-cold and physiological temperature (PT). In the slices prepared at CT, we found significant spine loss and reconstruction, synaptic vesicle rearrangement and decrease in synaptic proteins, all of which were not detected in slices prepared at PT. Consistent with these structural findings, slices prepared at PT showed higher release probability. Furthermore, preparation at PT allows electrophysiological recording immediately after slicing resulting in higher detectability of long-term depression (LTD) after motor learning compared with that at CT. These results indicate substantial advantages of the slice preparation at PT for investigating synaptic functions in different physiological conditions."}],"has_accepted_license":"1","external_id":{"isi":["000525582200001"],"pmid":["32265664"]},"status":"public","date_created":"2020-04-19T22:00:55Z","scopus_import":"1","publication":"Frontiers in Cellular Neuroscience","oa_version":"Published Version","corr_author":"1","type":"journal_article","project":[{"grant_number":"793482","call_identifier":"H2020","name":"Ultrastructural analysis of phosphoinositides in nerve terminals: distribution, dynamics and physiological roles in synaptic transmission","_id":"2659CC84-B435-11E9-9278-68D0E5697425"},{"grant_number":"694539","name":"In situ analysis of single channel subunit composition in neurons: physiological implication in synaptic plasticity and behaviour","call_identifier":"H2020","_id":"25CA28EA-B435-11E9-9278-68D0E5697425"},{"grant_number":"I03600","_id":"265CB4D0-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Optical control of synaptic function via adhesion molecules"},{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"}],"date_updated":"2025-06-12T07:16:39Z","ddc":["570"],"intvolume":"        14","publication_identifier":{"issn":["1662-5102"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","department":[{"_id":"JoDa"},{"_id":"RySh"}],"day":"19","oa":1,"title":"Advantages of acute brain slices prepared at physiological temperature in the characterization of synaptic functions","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"63","_id":"7665","quality_controlled":"1","date_published":"2020-03-19T00:00:00Z","publisher":"Frontiers Media","doi":"10.3389/fncel.2020.00063","file":[{"access_level":"open_access","creator":"dernst","relation":"main_file","content_type":"application/pdf","date_created":"2020-04-20T10:59:49Z","file_size":9227283,"file_name":"2020_FrontiersCellularNeurosc_Eguchi.pdf","file_id":"7668","date_updated":"2020-07-14T12:48:01Z","checksum":"1c145123c6f8dc3e2e4bd5a66a1ad60e"}],"isi":1},{"author":[{"full_name":"Edelsbrunner, Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner","orcid":"0000-0002-9823-6833","first_name":"Herbert"},{"last_name":"Ölsböck","first_name":"Katharina","orcid":"0000-0002-4672-8297","id":"4D4AA390-F248-11E8-B48F-1D18A9856A87","full_name":"Ölsböck, Katharina"}],"page":"759-775","publication_status":"published","file_date_updated":"2020-11-20T13:22:21Z","year":"2020","month":"03","volume":64,"abstract":[{"text":"Generalizing the decomposition of a connected planar graph into a tree and a dual tree, we prove a combinatorial analog of the classic Helmholtz–Hodge decomposition of a smooth vector field. Specifically, we show that for every polyhedral complex, K, and every dimension, p, there is a partition of the set of p-cells into a maximal p-tree, a maximal p-cotree, and a collection of p-cells whose cardinality is the p-th reduced Betti number of K. Given an ordering of the p-cells, this tri-partition is unique, and it can be computed by a matrix reduction algorithm that also constructs canonical bases of cycle and boundary groups.","lang":"eng"}],"status":"public","has_accepted_license":"1","external_id":{"isi":["000520918800001"]},"scopus_import":"1","oa_version":"Published Version","publication":"Discrete and Computational Geometry","date_created":"2020-04-19T22:00:56Z","corr_author":"1","type":"journal_article","article_type":"original","ec_funded":1,"citation":{"chicago":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>.","short":"H. Edelsbrunner, K. Ölsböck, Discrete and Computational Geometry 64 (2020) 759–775.","mla":"Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of an Ordered Complex.” <i>Discrete and Computational Geometry</i>, vol. 64, Springer Nature, 2020, pp. 759–75, doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>.","ama":"Edelsbrunner H, Ölsböck K. Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. 2020;64:759-775. doi:<a href=\"https://doi.org/10.1007/s00454-020-00188-x\">10.1007/s00454-020-00188-x</a>","ista":"Edelsbrunner H, Ölsböck K. 2020. Tri-partitions and bases of an ordered complex. Discrete and Computational Geometry. 64, 759–775.","ieee":"H. Edelsbrunner and K. Ölsböck, “Tri-partitions and bases of an ordered complex,” <i>Discrete and Computational Geometry</i>, vol. 64. Springer Nature, pp. 759–775, 2020.","apa":"Edelsbrunner, H., &#38; Ölsböck, K. (2020). Tri-partitions and bases of an ordered complex. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-020-00188-x\">https://doi.org/10.1007/s00454-020-00188-x</a>"},"language":[{"iso":"eng"}],"date_updated":"2025-04-14T07:48:36Z","ddc":["510"],"intvolume":"        64","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"grant_number":"788183","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35"}],"publication_identifier":{"issn":["01795376"],"eissn":["14320444"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","oa":1,"title":"Tri-partitions and bases of an ordered complex","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","department":[{"_id":"HeEd"}],"day":"20","_id":"7666","quality_controlled":"1","date_published":"2020-03-20T00:00:00Z","publisher":"Springer Nature","acknowledgement":"This project has received funding from the European Research Council under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 78818 Alpha). It is also partially supported by the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant No. I02979-N35 of the Austrian Science Fund (FWF).","file":[{"file_name":"2020_DiscreteCompGeo_Edelsbrunner.pdf","file_id":"8786","date_updated":"2020-11-20T13:22:21Z","checksum":"f8cc96e497f00c38340b5dafe0cb91d7","success":1,"file_size":701673,"date_created":"2020-11-20T13:22:21Z","content_type":"application/pdf","access_level":"open_access","creator":"dernst","relation":"main_file"}],"doi":"10.1007/s00454-020-00188-x","isi":1},{"article_number":"137175","_id":"7672","date_published":"2020-12-01T00:00:00Z","quality_controlled":"1","publisher":"Elsevier","isi":1,"doi":"10.1016/j.electacta.2020.137175","acknowledgement":"S.A.F. thanks the International Society of Electrochemistry for awarding the Tajima Prize 2019 “in recognition of outstanding re- searches on Li-Air batteries by the use of a range of in-situ elec- trochemical methods to achieve comprehensive understanding of the reactions taking place at the oxygen electrode”. This article is dedicated to the special issue of Electrochmica Acta associated with the awarding conference. S.A.F. is indebted to and the Austrian Federal Ministry of Science, Research and Economy and the Austrian Research Promotion Agency (grant No. 845364 ) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 636069). The authors thank J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH and G. Strohmeier for help with HPLC measurements, S. Eder for cyclic voltammetry measurements, and C. Slugovc for discussions and continuous support. We thank S. Borisov for access and advice with fluorescence measurements. We thank EL-Cell GmbH, Hamburg, Germany for providing the PAT-Cell-Press electrochemical cell.","file":[{"content_type":"application/pdf","date_created":"2020-10-01T13:20:45Z","creator":"dernst","relation":"main_file","access_level":"open_access","checksum":"1ab1aa2024d431e2a089ea336bc08298","success":1,"file_id":"8593","file_name":"2020_ElectrochimicaActa_Samojlov.pdf","date_updated":"2020-10-01T13:20:45Z","file_size":1404030}],"tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"article_processing_charge":"Yes (via OA deal)","title":"Surface and catalyst driven singlet oxygen formation in Li-O2 cells","oa":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","department":[{"_id":"StFr"}],"day":"01","has_accepted_license":"1","status":"public","external_id":{"isi":["000582869700060"]},"abstract":[{"lang":"eng","text":"Large overpotentials upon discharge and charge of Li-O2 cells have motivated extensive research into heterogeneous solid electrocatalysts or non-carbon electrodes with the aim to improve rate capability, round-trip efficiency and cycle life. These features are equally governed by parasitic reactions, which are now recognized to be caused by the highly reactive singlet oxygen (1O2). However, the link between the presence of electrocatalysts and 1O2 formation in metal-O2 cells is unknown. Here, we show that, compared to pristine carbon black electrodes, a representative selection of electrocatalysts or non-carbon electrodes (noble metal, transition metal compounds) may both slightly reduce or severely increase the 1O2 formation. The individual reaction steps, where the surfaces impact the 1O2 yield are deciphered, showing that 1O2 yield from superoxide disproportionation as well as the decomposition of trace H2O2 are sensitive to catalysts. Transition metal compounds in general are prone to increase 1O2."}],"type":"journal_article","corr_author":"1","publication":"Electrochimica Acta","scopus_import":"1","oa_version":"Published Version","date_created":"2020-04-20T19:29:31Z","language":[{"iso":"eng"}],"citation":{"ieee":"A. Samojlov, D. Schuster, J. Kahr, and S. A. Freunberger, “Surface and catalyst driven singlet oxygen formation in Li-O2 cells,” <i>Electrochimica Acta</i>, vol. 362, no. 12. Elsevier, 2020.","ista":"Samojlov A, Schuster D, Kahr J, Freunberger SA. 2020. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. Electrochimica Acta. 362(12), 137175.","ama":"Samojlov A, Schuster D, Kahr J, Freunberger SA. Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. 2020;362(12). doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>","apa":"Samojlov, A., Schuster, D., Kahr, J., &#38; Freunberger, S. A. (2020). Surface and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>","short":"A. Samojlov, D. Schuster, J. Kahr, S.A. Freunberger, Electrochimica Acta 362 (2020).","mla":"Samojlov, Aleksej, et al. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>, vol. 362, no. 12, 137175, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">10.1016/j.electacta.2020.137175</a>.","chicago":"Samojlov, Aleksej, David Schuster, Jürgen Kahr, and Stefan Alexander Freunberger. “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica Acta</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.electacta.2020.137175\">https://doi.org/10.1016/j.electacta.2020.137175</a>."},"article_type":"original","ddc":["540"],"date_updated":"2024-10-09T20:59:27Z","intvolume":"       362","author":[{"last_name":"Samojlov","first_name":"Aleksej","full_name":"Samojlov, Aleksej"},{"last_name":"Schuster","first_name":"David","full_name":"Schuster, David"},{"last_name":"Kahr","first_name":"Jürgen","full_name":"Kahr, Jürgen"},{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319"}],"file_date_updated":"2020-10-01T13:20:45Z","publication_status":"published","year":"2020","month":"12","volume":362,"issue":"12"},{"abstract":[{"lang":"eng","text":"For any free oriented Borel–Moore homology theory A, we construct an associative product on the A-theory of the stack of Higgs torsion sheaves over a projective curve C. We show that the resulting algebra AHa0C admits a natural shuffle presentation, and prove it is faithful when A is replaced with usual Borel–Moore homology groups. We also introduce moduli spaces of stable triples, heavily inspired by Nakajima quiver varieties, whose A-theory admits an AHa0C-action. These triples can be interpreted as certain sheaves on PC(ωC⊕OC). In particular, we obtain an action of AHa0C on the cohomology of Hilbert schemes of points on T∗C."}],"external_id":{"arxiv":["1801.01429"],"isi":["000526036400001"]},"has_accepted_license":"1","status":"public","oa_version":"Published Version","scopus_import":"1","date_created":"2020-04-26T22:00:44Z","publication":"Selecta Mathematica, New Series","corr_author":"1","type":"journal_article","article_type":"original","citation":{"chicago":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>.","mla":"Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2, 30, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>.","short":"S. Minets, Selecta Mathematica, New Series 26 (2020).","apa":"Minets, S. (2020). Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00029-020-00553-x\">https://doi.org/10.1007/s00029-020-00553-x</a>","ista":"Minets S. 2020. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. Selecta Mathematica, New Series. 26(2), 30.","ama":"Minets S. Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. 2020;26(2). doi:<a href=\"https://doi.org/10.1007/s00029-020-00553-x\">10.1007/s00029-020-00553-x</a>","ieee":"S. Minets, “Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces,” <i>Selecta Mathematica, New Series</i>, vol. 26, no. 2. Springer Nature, 2020."},"language":[{"iso":"eng"}],"date_updated":"2025-05-20T10:38:32Z","arxiv":1,"ddc":["510"],"intvolume":"        26","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"author":[{"id":"3E7C5304-F248-11E8-B48F-1D18A9856A87","full_name":"Minets, Sasha","first_name":"Sasha","orcid":"0000-0003-3883-1806","last_name":"Minets"}],"publication_status":"published","file_date_updated":"2020-07-14T12:48:02Z","year":"2020","month":"04","issue":"2","volume":26,"article_number":"30","_id":"7683","quality_controlled":"1","date_published":"2020-04-15T00:00:00Z","publisher":"Springer Nature","file":[{"file_size":792469,"checksum":"2368c4662629b4759295eb365323b2ad","date_updated":"2020-07-14T12:48:02Z","file_name":"2020_SelectaMathematica_Minets.pdf","file_id":"7690","relation":"main_file","creator":"dernst","access_level":"open_access","content_type":"application/pdf","date_created":"2020-04-28T10:57:58Z"}],"isi":1,"doi":"10.1007/s00029-020-00553-x","publication_identifier":{"eissn":["1420-9020"],"issn":["1022-1824"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","oa":1,"title":"Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and sheaves on surfaces","user_id":"9947682f-b9fa-11ee-9c4a-b3ffaafe6614","department":[{"_id":"TaHa"}],"day":"15"},{"article_processing_charge":"No","publication_identifier":{"eissn":["1097-4199"],"issn":["0896-6273"]},"day":"22","department":[{"_id":"JoCs"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"title":"Assembly-specific disruption of hippocampal replay leads to selective memory deficit","_id":"7684","date_published":"2020-04-22T00:00:00Z","quality_controlled":"1","isi":1,"doi":"10.1016/j.neuron.2020.01.021","publisher":"Elsevier","pmid":1,"page":"291-300.e6","author":[{"orcid":"0000-0002-1807-1929","first_name":"Igor","last_name":"Gridchyn","full_name":"Gridchyn, Igor","id":"4B60654C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Schönenberger","first_name":"Philipp","id":"3B9D816C-F248-11E8-B48F-1D18A9856A87","full_name":"Schönenberger, Philipp"},{"first_name":"Joseph","last_name":"O'Neill","id":"426376DC-F248-11E8-B48F-1D18A9856A87","full_name":"O'Neill, Joseph"},{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","full_name":"Csicsvari, Jozsef L","first_name":"Jozsef L","orcid":"0000-0002-5193-4036","last_name":"Csicsvari"}],"issue":"2","related_material":{"link":[{"description":"News on IST Homepage","relation":"press_release","url":"https://ist.ac.at/en/news/librarian-of-memory/"}]},"volume":106,"month":"04","year":"2020","publication_status":"published","article_type":"original","citation":{"chicago":"Gridchyn, Igor, Philipp Schönenberger, Joseph O’Neill, and Jozsef L Csicsvari. “Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory Deficit.” <i>Neuron</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.neuron.2020.01.021\">https://doi.org/10.1016/j.neuron.2020.01.021</a>.","mla":"Gridchyn, Igor, et al. “Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory Deficit.” <i>Neuron</i>, vol. 106, no. 2, Elsevier, 2020, p. 291–300.e6, doi:<a href=\"https://doi.org/10.1016/j.neuron.2020.01.021\">10.1016/j.neuron.2020.01.021</a>.","short":"I. Gridchyn, P. Schönenberger, J. O’Neill, J.L. Csicsvari, Neuron 106 (2020) 291–300.e6.","apa":"Gridchyn, I., Schönenberger, P., O’Neill, J., &#38; Csicsvari, J. L. (2020). Assembly-specific disruption of hippocampal replay leads to selective memory deficit. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2020.01.021\">https://doi.org/10.1016/j.neuron.2020.01.021</a>","ieee":"I. Gridchyn, P. Schönenberger, J. O’Neill, and J. L. Csicsvari, “Assembly-specific disruption of hippocampal replay leads to selective memory deficit,” <i>Neuron</i>, vol. 106, no. 2. Elsevier, p. 291–300.e6, 2020.","ista":"Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. 2020. Assembly-specific disruption of hippocampal replay leads to selective memory deficit. Neuron. 106(2), 291–300.e6.","ama":"Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. Assembly-specific disruption of hippocampal replay leads to selective memory deficit. <i>Neuron</i>. 2020;106(2):291-300.e6. doi:<a href=\"https://doi.org/10.1016/j.neuron.2020.01.021\">10.1016/j.neuron.2020.01.021</a>"},"ec_funded":1,"language":[{"iso":"eng"}],"date_created":"2020-04-26T22:00:45Z","scopus_import":"1","publication":"Neuron","oa_version":"Published Version","type":"journal_article","main_file_link":[{"url":"https://doi.org/10.1016/j.neuron.2020.01.021","open_access":"1"}],"status":"public","external_id":{"pmid":["32070475"],"isi":["000528268200013"]},"project":[{"name":"Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex","call_identifier":"FP7","_id":"257A4776-B435-11E9-9278-68D0E5697425","grant_number":"281511"}],"intvolume":"       106","date_updated":"2026-06-18T19:26:54Z","ddc":["570"]},{"abstract":[{"text":"A working group, which was established within the Network of Repository Managers  (RepManNet),  has  dealt  with  common  certifications  for  repositories.  In addition,  current  requirements  of  the  research  funding  agencies  FWF  and  EU  were also taken into account. The Core Trust Seal was examined in more detail. For this purpose,  a  questionnaire  was  sent  to  those  organizations  that  are  already  certified with CTS in Austria. The answers were summarized and evaluated anonymously. It is recommended to go for a repository certification. Moreover, the development of a DINI certificate in Austria is strongly suggested.","lang":"eng"},{"lang":"ger","text":" Eine Arbeitsgruppe, die im Rahmen des Netzwerks für RepositorienmanagerInnen (RepManNet) entstanden ist, hat sich mit gängigen Zertifizierungen für Repositorien beschäftigt. Weiters wurden aktuelle Vorgaben der Forschungsförderer FWF und EU herangezogen. Das Core Trust Seal wurde genauer betrachtet. Hierfür  wurden jenen  Organisationen,  die  in  Österreich  bereits  mit  CTS  zertifiziert sind, ein Fragebogen übermittelt. Die Antworten wurden anonymisiert zusammengefasst und ausgewertet. Plädiert wird für eine Zertifizierung von Repositorien und die Entwicklung einer DINI-Zertifizierung in Österreich."}],"has_accepted_license":"1","status":"public","external_id":{"oaworkid":["W3021112752"]},"scopus_import":"1","oa_version":"Published Version","date_created":"2020-04-28T08:37:38Z","publication":"Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare","corr_author":"1","type":"journal_article","citation":{"apa":"Ernst, D., Novotny, G., &#38; Schönher, E. M. (2020). (Core Trust) Seal your repository! <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare. <a href=\"https://doi.org/10.31263/voebm.v73i1.3491\">https://doi.org/10.31263/voebm.v73i1.3491</a>","ista":"Ernst D, Novotny G, Schönher EM. 2020. (Core Trust) Seal your repository! Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare. 73(1), 46–59.","ama":"Ernst D, Novotny G, Schönher EM. (Core Trust) Seal your repository! <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>. 2020;73(1):46-59. doi:<a href=\"https://doi.org/10.31263/voebm.v73i1.3491\">10.31263/voebm.v73i1.3491</a>","ieee":"D. Ernst, G. Novotny, and E. M. Schönher, “(Core Trust) Seal your repository!,” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>, vol. 73, no. 1. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, pp. 46–59, 2020.","mla":"Ernst, Doris, et al. “(Core Trust) Seal your repository!” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>, vol. 73, no. 1, Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2020, pp. 46–59, doi:<a href=\"https://doi.org/10.31263/voebm.v73i1.3491\">10.31263/voebm.v73i1.3491</a>.","short":"D. Ernst, G. Novotny, E.M. Schönher, Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare 73 (2020) 46–59.","chicago":"Ernst, Doris, Gertraud Novotny, and Eva Maria Schönher. “(Core Trust) Seal your repository!” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2020. <a href=\"https://doi.org/10.31263/voebm.v73i1.3491\">https://doi.org/10.31263/voebm.v73i1.3491</a>."},"article_type":"original","language":[{"iso":"ger"}],"date_updated":"2026-03-16T13:47:31Z","ddc":["020"],"intvolume":"        73","author":[{"last_name":"Ernst","orcid":"0000-0002-2354-0195","first_name":"Doris","full_name":"Ernst, Doris","id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Novotny, Gertraud","first_name":"Gertraud","last_name":"Novotny"},{"full_name":"Schönher, Eva Maria","last_name":"Schönher","first_name":"Eva Maria"}],"page":"46-59","publication_status":"published","file_date_updated":"2024-03-12T10:12:33Z","year":"2020","month":"04","issue":"1","volume":73,"_id":"7687","date_published":"2020-04-28T00:00:00Z","oaworkid":1,"publisher":"Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare","popular_science":"1","doi":"10.31263/voebm.v73i1.3491","file":[{"creator":"dernst","relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2020-06-17T10:50:13Z","file_size":579291,"checksum":"fee784f15a489deb7def6ccf8c5bf8c3","file_id":"7970","file_name":"2020_VOEB_Ernst.pdf","date_updated":"2024-03-12T10:12:33Z"}],"publication_identifier":{"issn":["1022-2588"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"No","oa":1,"title":"(Core Trust) Seal your repository!","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"E-Lib"}],"day":"28"},{"publisher":"Institute of Science and Technology Austria","doi":"10.15479/AT:ISTA:7689","project":[{"name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS","call_identifier":"H2020","_id":"237E5020-32DE-11EA-91FC-C7463DDC885E","grant_number":"862046"},{"call_identifier":"FWF","name":"Towards scalable hut wire quantum devices","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","grant_number":"P32235"}],"file":[{"file_name":"DOI_ZeroFieldSplitting.zip","file_id":"7786","date_updated":"2020-07-14T12:48:02Z","checksum":"d23c0cb9e2d19e14e2f902b88b97c05d","file_size":5514403,"date_created":"2020-05-01T15:13:28Z","content_type":"application/x-zip-compressed","access_level":"open_access","creator":"gkatsaro","relation":"main_file"}],"ddc":["530"],"date_updated":"2025-04-15T08:39:16Z","ec_funded":1,"citation":{"mla":"Katsaros, Georgios. <i>Supplementary Data for “Zero Field Splitting of Heavy-Hole States in Quantum Dots.”</i> Institute of Science and Technology Austria, 2020, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","short":"G. Katsaros, (2020).","apa":"Katsaros, G. (2020). Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>","ieee":"G. Katsaros, “Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots.’” Institute of Science and Technology Austria, 2020.","ama":"Katsaros G. Supplementary data for “Zero field splitting of heavy-hole states in quantum dots.” 2020. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>","ista":"Katsaros G. 2020. Supplementary data for ‘Zero field splitting of heavy-hole states in quantum dots’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">10.15479/AT:ISTA:7689</a>.","chicago":"Katsaros, Georgios. “Supplementary Data for ‘Zero Field Splitting of Heavy-Hole States in Quantum Dots.’” Institute of Science and Technology Austria, 2020. <a href=\"https://doi.org/10.15479/AT:ISTA:7689\">https://doi.org/10.15479/AT:ISTA:7689</a>."},"_id":"7689","date_published":"2020-05-01T00:00:00Z","status":"public","has_accepted_license":"1","abstract":[{"text":"These are the supplementary research data to the publication \"Zero field splitting of heavy-hole states in quantum dots\". All matrix files have the same format. Within each column the bias voltage is changed. Each column corresponds to either a different gate voltage or magnetic field. The voltage values are given in mV, the current values in pA. Find a specific description in the included Readme file.\r\n","lang":"eng"}],"corr_author":"1","type":"research_data","date_created":"2020-05-01T15:14:46Z","oa_version":"Published Version","month":"05","department":[{"_id":"GeKa"}],"related_material":{"record":[{"relation":"used_in_publication","id":"8203","status":"public"}]},"day":"01","title":"Supplementary data for \"Zero field splitting of heavy-hole states in quantum dots\"","contributor":[{"contributor_type":"contact_person","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","first_name":"Georgios","last_name":"Katsaros"}],"file_date_updated":"2020-07-14T12:48:02Z","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2020","tmp":{"short":"CC0 (1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png","name":"Creative Commons Public Domain Dedication (CC0 1.0)"},"article_processing_charge":"No","author":[{"last_name":"Katsaros","first_name":"Georgios","orcid":"0000-0001-8342-202X","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","full_name":"Katsaros, Georgios"}]},{"department":[{"_id":"JiFr"}],"day":"01","oa":1,"title":"High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication_identifier":{"eissn":["1532-2548"],"issn":["0032-0889"]},"article_processing_charge":"No","publisher":"American Society of Plant Biologists","isi":1,"doi":"10.1104/pp.20.00178","_id":"7695","quality_controlled":"1","date_published":"2020-07-01T00:00:00Z","month":"07","issue":"3","volume":183,"publication_status":"published","year":"2020","page":"986-997","pmid":1,"author":[{"full_name":"Wang, J","first_name":"J","last_name":"Wang"},{"first_name":"E","last_name":"Mylle","full_name":"Mylle, E"},{"id":"46A62C3A-F248-11E8-B48F-1D18A9856A87","full_name":"Johnson, Alexander J","first_name":"Alexander J","orcid":"0000-0002-2739-8843","last_name":"Johnson"},{"full_name":"Besbrugge, N","last_name":"Besbrugge","first_name":"N"},{"full_name":"De Jaeger, G","last_name":"De Jaeger","first_name":"G"},{"full_name":"Friml, Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jiří","last_name":"Friml"},{"last_name":"Pleskot","first_name":"R","full_name":"Pleskot, R"},{"last_name":"van Damme","first_name":"D","full_name":"van Damme, D"}],"project":[{"_id":"26538374-B435-11E9-9278-68D0E5697425","name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF","grant_number":"I03630"}],"date_updated":"2025-04-15T07:32:09Z","intvolume":"       183","citation":{"chicago":"Wang, J, E Mylle, Alexander J Johnson, N Besbrugge, G De Jaeger, Jiří Friml, R Pleskot, and D van Damme. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>. American Society of Plant Biologists, 2020. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>.","mla":"Wang, J., et al. “High Temporal Resolution Reveals Simultaneous Plasma Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>, vol. 183, no. 3, American Society of Plant Biologists, 2020, pp. 986–97, doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>.","short":"J. Wang, E. Mylle, A.J. Johnson, N. Besbrugge, G. De Jaeger, J. Friml, R. Pleskot, D. van Damme, Plant Physiology 183 (2020) 986–997.","apa":"Wang, J., Mylle, E., Johnson, A. J., Besbrugge, N., De Jaeger, G., Friml, J., … van Damme, D. (2020). High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1104/pp.20.00178\">https://doi.org/10.1104/pp.20.00178</a>","ista":"Wang J, Mylle E, Johnson AJ, Besbrugge N, De Jaeger G, Friml J, Pleskot R, van Damme D. 2020. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. Plant Physiology. 183(3), 986–997.","ieee":"J. Wang <i>et al.</i>, “High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits,” <i>Plant Physiology</i>, vol. 183, no. 3. American Society of Plant Biologists, pp. 986–997, 2020.","ama":"Wang J, Mylle E, Johnson AJ, et al. High temporal resolution reveals simultaneous plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. 2020;183(3):986-997. doi:<a href=\"https://doi.org/10.1104/pp.20.00178\">10.1104/pp.20.00178</a>"},"article_type":"original","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"The TPLATE complex (TPC) is a key endocytic adaptor protein complex in plants. TPC in Arabidopsis (Arabidopsis thaliana) contains six evolutionarily conserved subunits and two plant-specific subunits, AtEH1/Pan1 and AtEH2/Pan1, although cytoplasmic proteins are not associated with the hexameric subcomplex in the cytoplasm. To investigate the dynamic assembly of the octameric TPC at the plasma membrane (PM), we performed state-of-the-art dual-color live cell imaging at physiological and lowered temperatures. Lowering the temperature slowed down endocytosis, thereby enhancing the temporal resolution of the differential recruitment of endocytic components. Under both normal and lowered temperature conditions, the core TPC subunit TPLATE and the AtEH/Pan1 proteins exhibited simultaneous recruitment at the PM. These results, together with co-localization analysis of different TPC subunits, allow us to conclude that TPC in plant cells is not recruited to the PM sequentially but as an octameric complex."}],"external_id":{"isi":["000550682000018"],"pmid":["32321842"]},"status":"public","date_created":"2020-04-29T15:23:00Z","oa_version":"Preprint","scopus_import":"1","publication":"Plant Physiology","type":"journal_article","main_file_link":[{"url":"https://doi.org/10.1101/2020.02.13.948109","open_access":"1"}]},{"month":"09","volume":227,"issue":"5","publication_status":"published","file_date_updated":"2020-11-24T12:19:38Z","year":"2020","page":"1406-1416","pmid":1,"author":[{"full_name":"Zhang, Yuzhou","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2627-6956","first_name":"Yuzhou","last_name":"Zhang"},{"orcid":"0000-0003-1618-2737","first_name":"Corinna","last_name":"Hartinger","full_name":"Hartinger, Corinna","id":"AEFB2266-8ABF-11EA-AA39-812C3623CBE4"},{"first_name":"Xiaojuan","last_name":"Wang","full_name":"Wang, Xiaojuan"},{"last_name":"Friml","first_name":"Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří"}],"project":[{"name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985"},{"name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF","_id":"26538374-B435-11E9-9278-68D0E5697425","grant_number":"I03630"},{"name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734"}],"ddc":["580"],"date_updated":"2025-04-14T07:45:03Z","intvolume":"       227","language":[{"iso":"eng"}],"article_type":"original","citation":{"chicago":"Zhang, Yuzhou, Corinna Hartinger, Xiaojuan Wang, and Jiří Friml. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>. Wiley, 2020. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>.","apa":"Zhang, Y., Hartinger, C., Wang, X., &#38; Friml, J. (2020). Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16629\">https://doi.org/10.1111/nph.16629</a>","ista":"Zhang Y, Hartinger C, Wang X, Friml J. 2020. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. New Phytologist. 227(5), 1406–1416.","ama":"Zhang Y, Hartinger C, Wang X, Friml J. Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>. 2020;227(5):1406-1416. doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>","ieee":"Y. Zhang, C. Hartinger, X. Wang, and J. Friml, “Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters,” <i>New Phytologist</i>, vol. 227, no. 5. Wiley, pp. 1406–1416, 2020.","mla":"Zhang, Yuzhou, et al. “Directional Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>, vol. 227, no. 5, Wiley, 2020, pp. 1406–16, doi:<a href=\"https://doi.org/10.1111/nph.16629\">10.1111/nph.16629</a>.","short":"Y. Zhang, C. Hartinger, X. Wang, J. Friml, New Phytologist 227 (2020) 1406–1416."},"ec_funded":1,"has_accepted_license":"1","status":"public","external_id":{"pmid":["32350870"],"isi":["000534092400001"]},"abstract":[{"lang":"eng","text":"* Morphogenesis and adaptive tropic growth in plants depend on gradients of the phytohormone auxin, mediated by the membrane‐based PIN‐FORMED (PIN) auxin transporters. PINs localize to a particular side of the plasma membrane (PM) or to the endoplasmic reticulum (ER) to directionally transport auxin and maintain intercellular and intracellular auxin homeostasis, respectively. However, the molecular cues that confer their diverse cellular localizations remain largely unknown.\r\n* In this study, we systematically swapped the domains between ER‐ and PM‐localized PIN proteins, as well as between apical and basal PM‐localized PINs from Arabidopsis thaliana , to shed light on why PIN family members with similar topological structures reside at different membrane compartments within cells.\r\n* Our results show that not only do the N‐ and C‐terminal transmembrane domains (TMDs) and central hydrophilic loop contribute to their differential subcellular localizations and cellular polarity, but that the pairwise‐matched N‐ and C‐terminal TMDs resulting from intramolecular domain–domain coevolution are also crucial for their divergent patterns of localization.\r\n* These findings illustrate the complexity of the evolutionary path of PIN proteins in acquiring their plethora of developmental functions and adaptive growth in plants."}],"type":"journal_article","corr_author":"1","oa_version":"Published Version","scopus_import":"1","date_created":"2020-04-30T08:43:29Z","publication":"New Phytologist","department":[{"_id":"JiFr"}],"day":"01","title":"Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"issn":["0028-646X"],"eissn":["1469-8137"]},"article_processing_charge":"Yes (via OA deal)","publisher":"Wiley","doi":"10.1111/nph.16629","isi":1,"file":[{"file_size":3643395,"date_updated":"2020-11-24T12:19:38Z","file_id":"8799","file_name":"2020_09_NewPhytologist_Zhang.pdf","success":1,"checksum":"8e8150dbbba8cb65b72f81d1f0864b8b","access_level":"open_access","relation":"main_file","creator":"dernst","date_created":"2020-11-24T12:19:38Z","content_type":"application/pdf"}],"quality_controlled":"1","_id":"7697","date_published":"2020-09-01T00:00:00Z"},{"intvolume":"        11","OA_place":"publisher","date_updated":"2024-10-15T12:43:32Z","OA_type":"gold","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-020-15107-0"}],"type":"journal_article","oa_version":"Published Version","publication":"Nature Communications","date_created":"2020-04-30T10:39:33Z","status":"public","abstract":[{"text":"The growing sample size of genome-wide association studies has facilitated the discovery of gene-environment interactions (GxE). Here we propose a maximum likelihood method to estimate the contribution of GxE to continuous traits taking into account all interacting environmental variables, without the need to measure any. Extensive simulations demonstrate that our method provides unbiased interaction estimates and excellent coverage. We also offer strategies to distinguish specific GxE from general scale effects. Applying our method to 32 traits in the UK Biobank reveals that while the genetic risk score (GRS) of 376 variants explains 5.2% of body mass index (BMI) variance, GRSxE explains an additional 1.9%. Nevertheless, this interaction holds for any variable with identical correlation to BMI as the GRS, hence may not be GRS-specific. Still, we observe that the global contribution of specific GRSxE to complex traits is substantial for nine obesity-related measures (including leg impedance and trunk fat-free mass).","lang":"eng"}],"language":[{"iso":"eng"}],"citation":{"short":"J. Sulc, N. Mounier, F. Günther, T. Winkler, A.R. Wood, T.M. Frayling, I.M. Heid, M.R. Robinson, Z. Kutalik, Nature Communications 11 (2020).","mla":"Sulc, Jonathan, et al. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>, vol. 11, 1385, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>.","ista":"Sulc J, Mounier N, Günther F, Winkler T, Wood AR, Frayling TM, Heid IM, Robinson MR, Kutalik Z. 2020. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. Nature Communications. 11, 1385.","ieee":"J. Sulc <i>et al.</i>, “Quantification of the overall contribution of gene-environment interaction for obesity-related traits,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","ama":"Sulc J, Mounier N, Günther F, et al. Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-15107-0\">10.1038/s41467-020-15107-0</a>","apa":"Sulc, J., Mounier, N., Günther, F., Winkler, T., Wood, A. R., Frayling, T. M., … Kutalik, Z. (2020). Quantification of the overall contribution of gene-environment interaction for obesity-related traits. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>","chicago":"Sulc, Jonathan, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R. Wood, Timothy M. Frayling, Iris M. Heid, Matthew Richard Robinson, and Zoltán Kutalik. “Quantification of the Overall Contribution of Gene-Environment Interaction for Obesity-Related Traits.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-15107-0\">https://doi.org/10.1038/s41467-020-15107-0</a>."},"DOAJ_listed":"1","article_type":"original","year":"2020","publication_status":"published","volume":11,"month":"03","author":[{"last_name":"Sulc","first_name":"Jonathan","full_name":"Sulc, Jonathan"},{"full_name":"Mounier, Ninon","last_name":"Mounier","first_name":"Ninon"},{"full_name":"Günther, Felix","first_name":"Felix","last_name":"Günther"},{"full_name":"Winkler, Thomas","last_name":"Winkler","first_name":"Thomas"},{"full_name":"Wood, Andrew R.","last_name":"Wood","first_name":"Andrew R."},{"first_name":"Timothy M.","last_name":"Frayling","full_name":"Frayling, Timothy M."},{"full_name":"Heid, Iris M.","last_name":"Heid","first_name":"Iris M."},{"full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","last_name":"Robinson"},{"last_name":"Kutalik","first_name":"Zoltán","full_name":"Kutalik, Zoltán"}],"extern":"1","doi":"10.1038/s41467-020-15107-0","publisher":"Springer Nature","_id":"7707","quality_controlled":"1","date_published":"2020-03-20T00:00:00Z","article_number":"1385","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","title":"Quantification of the overall contribution of gene-environment interaction for obesity-related traits","oa":1,"day":"20","article_processing_charge":"No","publication_identifier":{"issn":["2041-1723"]}},{"year":"2020","publication_status":"published","volume":5,"month":"02","author":[{"last_name":"Nabais","first_name":"Marta F.","full_name":"Nabais, Marta F."},{"full_name":"Lin, Tian","first_name":"Tian","last_name":"Lin"},{"full_name":"Benyamin, Beben","first_name":"Beben","last_name":"Benyamin"},{"full_name":"Williams, Kelly L.","first_name":"Kelly L.","last_name":"Williams"},{"full_name":"Garton, Fleur C.","last_name":"Garton","first_name":"Fleur C."},{"first_name":"Anna A. E.","last_name":"Vinkhuyzen","full_name":"Vinkhuyzen, Anna A. E."},{"full_name":"Zhang, Futao","first_name":"Futao","last_name":"Zhang"},{"last_name":"Vallerga","first_name":"Costanza L.","full_name":"Vallerga, Costanza L."},{"full_name":"Restuadi, Restuadi","first_name":"Restuadi","last_name":"Restuadi"},{"full_name":"Freydenzon, Anna","last_name":"Freydenzon","first_name":"Anna"},{"full_name":"Zwamborn, Ramona A. J.","last_name":"Zwamborn","first_name":"Ramona A. J."},{"full_name":"Hop, Paul J.","last_name":"Hop","first_name":"Paul J."},{"full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","last_name":"Robinson"},{"last_name":"Gratten","first_name":"Jacob","full_name":"Gratten, Jacob"},{"first_name":"Peter M.","last_name":"Visscher","full_name":"Visscher, Peter M."},{"full_name":"Hannon, Eilis","last_name":"Hannon","first_name":"Eilis"},{"first_name":"Jonathan","last_name":"Mill","full_name":"Mill, Jonathan"},{"first_name":"Matthew A.","last_name":"Brown","full_name":"Brown, Matthew A."},{"full_name":"Laing, Nigel G.","first_name":"Nigel G.","last_name":"Laing"},{"last_name":"Mather","first_name":"Karen A.","full_name":"Mather, Karen A."},{"full_name":"Sachdev, Perminder S.","last_name":"Sachdev","first_name":"Perminder S."},{"last_name":"Ngo","first_name":"Shyuan T.","full_name":"Ngo, Shyuan T."},{"full_name":"Steyn, Frederik J.","first_name":"Frederik J.","last_name":"Steyn"},{"last_name":"Wallace","first_name":"Leanne","full_name":"Wallace, Leanne"},{"full_name":"Henders, Anjali K.","last_name":"Henders","first_name":"Anjali K."},{"first_name":"Merrilee","last_name":"Needham","full_name":"Needham, Merrilee"},{"last_name":"Veldink","first_name":"Jan H.","full_name":"Veldink, Jan H."},{"first_name":"Susan","last_name":"Mathers","full_name":"Mathers, Susan"},{"full_name":"Nicholson, Garth","last_name":"Nicholson","first_name":"Garth"},{"first_name":"Dominic B.","last_name":"Rowe","full_name":"Rowe, Dominic B."},{"full_name":"Henderson, Robert D.","last_name":"Henderson","first_name":"Robert D."},{"full_name":"McCombe, Pamela A.","last_name":"McCombe","first_name":"Pamela A."},{"last_name":"Pamphlett","first_name":"Roger","full_name":"Pamphlett, Roger"},{"full_name":"Yang, Jian","first_name":"Jian","last_name":"Yang"},{"last_name":"Blair","first_name":"Ian P.","full_name":"Blair, Ian P."},{"first_name":"Allan F.","last_name":"McRae","full_name":"McRae, Allan F."},{"first_name":"Naomi R.","last_name":"Wray","full_name":"Wray, Naomi R."}],"OA_place":"publisher","intvolume":"         5","date_updated":"2024-10-15T12:41:56Z","OA_type":"gold","type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41525-020-0118-3"}],"date_created":"2020-04-30T10:39:54Z","oa_version":"Published Version","publication":"npj Genomic Medicine","status":"public","abstract":[{"text":"We conducted DNA methylation association analyses using Illumina 450K data from whole blood for an Australian amyotrophic lateral sclerosis (ALS) case–control cohort (782 cases and 613 controls). Analyses used mixed linear models as implemented in the OSCA software. We found a significantly higher proportion of neutrophils in cases compared to controls which replicated in an independent cohort from the Netherlands (1159 cases and 637 controls). The OSCA MOMENT linear mixed model has been shown in simulations to best account for confounders. When combined in a methylation profile score, the 25 most-associated probes identified by MOMENT significantly classified case–control status in the Netherlands sample (area under the curve, AUC = 0.65, CI95% = [0.62–0.68], p = 8.3 × 10−22). The maximum AUC achieved was 0.69 (CI95% = [0.66–0.71], p = 4.3 × 10−34) when cell-type proportion was included in the predictor.","lang":"eng"}],"language":[{"iso":"eng"}],"citation":{"ama":"Nabais MF, Lin T, Benyamin B, et al. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>npj Genomic Medicine</i>. 2020;5. doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>","ista":"Nabais MF, Lin T, Benyamin B, Williams KL, Garton FC, Vinkhuyzen AAE, Zhang F, Vallerga CL, Restuadi R, Freydenzon A, Zwamborn RAJ, Hop PJ, Robinson MR, Gratten J, Visscher PM, Hannon E, Mill J, Brown MA, Laing NG, Mather KA, Sachdev PS, Ngo ST, Steyn FJ, Wallace L, Henders AK, Needham M, Veldink JH, Mathers S, Nicholson G, Rowe DB, Henderson RD, McCombe PA, Pamphlett R, Yang J, Blair IP, McRae AF, Wray NR. 2020. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine. 5, 10.","ieee":"M. F. Nabais <i>et al.</i>, “Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis,” <i>npj Genomic Medicine</i>, vol. 5. Springer Nature, 2020.","apa":"Nabais, M. F., Lin, T., Benyamin, B., Williams, K. L., Garton, F. C., Vinkhuyzen, A. A. E., … Wray, N. R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. <i>Npj Genomic Medicine</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>","short":"M.F. Nabais, T. Lin, B. Benyamin, K.L. Williams, F.C. Garton, A.A.E. Vinkhuyzen, F. Zhang, C.L. Vallerga, R. Restuadi, A. Freydenzon, R.A.J. Zwamborn, P.J. Hop, M.R. Robinson, J. Gratten, P.M. Visscher, E. Hannon, J. Mill, M.A. Brown, N.G. Laing, K.A. Mather, P.S. Sachdev, S.T. Ngo, F.J. Steyn, L. Wallace, A.K. Henders, M. Needham, J.H. Veldink, S. Mathers, G. Nicholson, D.B. Rowe, R.D. Henderson, P.A. McCombe, R. Pamphlett, J. Yang, I.P. Blair, A.F. McRae, N.R. Wray, Npj Genomic Medicine 5 (2020).","mla":"Nabais, Marta F., et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>, vol. 5, 10, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41525-020-0118-3\">10.1038/s41525-020-0118-3</a>.","chicago":"Nabais, Marta F., Tian Lin, Beben Benyamin, Kelly L. Williams, Fleur C. Garton, Anna A. E. Vinkhuyzen, Futao Zhang, et al. “Significant Out-of-Sample Classification from Methylation Profile Scoring for Amyotrophic Lateral Sclerosis.” <i>Npj Genomic Medicine</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41525-020-0118-3\">https://doi.org/10.1038/s41525-020-0118-3</a>."},"article_type":"original","DOAJ_listed":"1","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","title":"Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis","oa":1,"day":"27","article_processing_charge":"No","publication_identifier":{"issn":["2056-7944"]},"extern":"1","doi":"10.1038/s41525-020-0118-3","publisher":"Springer Nature","_id":"7708","quality_controlled":"1","date_published":"2020-02-27T00:00:00Z","article_number":"10"},{"OA_type":"gold","intvolume":"         6","OA_place":"publisher","date_updated":"2024-10-15T12:55:13Z","ddc":["570"],"DOAJ_listed":"1","citation":{"chicago":"Kimchi, Ofer, Carl Peter Goodrich, Alexis Courbet, Agnese I. Curatolo, Nicholas B. Woodall, David Baker, and Michael P. Brenner. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, 2020. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>.","short":"O. Kimchi, C.P. Goodrich, A. Courbet, A.I. Curatolo, N.B. Woodall, D. Baker, M.P. Brenner, Science Advances 6 (2020).","mla":"Kimchi, Ofer, et al. “Self-Assembly-Based Posttranslational Protein Oscillators.” <i>Science Advances</i>, vol. 6, no. 51, eabc1939, 2020, doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>.","ista":"Kimchi O, Goodrich CP, Courbet A, Curatolo AI, Woodall NB, Baker D, Brenner MP. 2020. Self-assembly-based posttranslational protein oscillators. Science Advances. 6(51), eabc1939.","ieee":"O. Kimchi <i>et al.</i>, “Self-assembly-based posttranslational protein oscillators,” <i>Science Advances</i>, vol. 6, no. 51. 2020.","ama":"Kimchi O, Goodrich CP, Courbet A, et al. Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. 2020;6(51). doi:<a href=\"https://doi.org/10.1126/sciadv.abc1939\">10.1126/sciadv.abc1939</a>","apa":"Kimchi, O., Goodrich, C. P., Courbet, A., Curatolo, A. I., Woodall, N. B., Baker, D., &#38; Brenner, M. P. (2020). Self-assembly-based posttranslational protein oscillators. <i>Science Advances</i>. <a href=\"https://doi.org/10.1126/sciadv.abc1939\">https://doi.org/10.1126/sciadv.abc1939</a>"},"article_type":"original","language":[{"iso":"eng"}],"publication":"Science Advances","oa_version":"Published Version","date_created":"2020-04-30T12:07:55Z","type":"journal_article","abstract":[{"text":"Recent advances in synthetic posttranslational protein circuits are substantially impacting the landscape of cellular engineering and offer several advantages compared to traditional gene circuits. However, engineering dynamic phenomena such as oscillations in protein-level circuits remains an outstanding challenge. Few examples of biological posttranslational oscillators are known, necessitating theoretical progress to determine realizable oscillators. We construct mathematical models for two posttranslational oscillators, using few components that interact only through reversible binding and phosphorylation/dephosphorylation reactions. Our designed oscillators rely on the self-assembly of two protein species into multimeric functional enzymes that respectively inhibit and enhance this self-assembly. We limit our analysis to within experimental constraints, finding (i) significant portions of the restricted parameter space yielding oscillations and (ii) that oscillation periods can be tuned by several orders of magnitude using recent advances in computational protein design. Our work paves the way for the rational design and realization of protein-based dynamic systems.","lang":"eng"}],"status":"public","has_accepted_license":"1","issue":"51","volume":6,"month":"12","year":"2020","publication_status":"published","file_date_updated":"2021-04-12T08:33:23Z","author":[{"first_name":"Ofer","last_name":"Kimchi","full_name":"Kimchi, Ofer"},{"id":"EB352CD2-F68A-11E9-89C5-A432E6697425","full_name":"Goodrich, Carl Peter","first_name":"Carl Peter","orcid":"0000-0002-1307-5074","last_name":"Goodrich"},{"first_name":"Alexis","last_name":"Courbet","full_name":"Courbet, Alexis"},{"full_name":"Curatolo, Agnese I.","first_name":"Agnese I.","last_name":"Curatolo"},{"last_name":"Woodall","first_name":"Nicholas B.","full_name":"Woodall, Nicholas B."},{"first_name":"David","last_name":"Baker","full_name":"Baker, David"},{"full_name":"Brenner, Michael P.","last_name":"Brenner","first_name":"Michael P."}],"file":[{"file_name":"2020_ScienceAdv_Kimchi.pdf","file_id":"9320","date_updated":"2021-04-12T08:33:23Z","checksum":"eb6d950b6a68ddc4a2fb31ec80a2a1bd","success":1,"file_size":1259758,"content_type":"application/pdf","date_created":"2021-04-12T08:33:23Z","access_level":"open_access","creator":"dernst","relation":"main_file"}],"doi":"10.1126/sciadv.abc1939","extern":"1","_id":"7778","date_published":"2020-12-16T00:00:00Z","quality_controlled":"1","article_number":"eabc1939","day":"16","user_id":"0043cee0-e5fc-11ee-9736-f83bc23afbf0","oa":1,"title":"Self-assembly-based posttranslational protein oscillators","article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"date_published":"2020-08-01T00:00:00Z","_id":"7788","quality_controlled":"1","article_number":"148213","doi":"10.1016/j.bbabio.2020.148213","isi":1,"file":[{"content_type":"application/pdf","date_created":"2020-05-04T12:25:19Z","access_level":"open_access","relation":"main_file","creator":"dernst","date_updated":"2020-07-14T12:48:03Z","file_id":"7798","file_name":"2020_BBA_Adjobo_Hermans.pdf","checksum":"a9b152381307cf45fe266a8dc5640388","file_size":3826792}],"publisher":"Elsevier","article_processing_charge":"No","publication_identifier":{"issn":["0005-2728"],"eissn":["1879-2650"]},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"day":"01","department":[{"_id":"LeSa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"title":"NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2","citation":{"chicago":"Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand, et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>.","short":"M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).","mla":"Adjobo-Hermans, Merel J. W., et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8, 148213, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>.","ista":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, Wojtala A, Van Emst-De Vries SE, Wagenaars JA, Van Den Brand M, Rodenburg RJ, Smeitink JAM, Nijtmans LG, Sazanov LA, Wieckowski MR, Koopman WJH. 2020. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics. 1861(8), 148213.","ama":"Adjobo-Hermans MJW, De Haas R, Willems PHGM, et al. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. 2020;1861(8). doi:<a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">10.1016/j.bbabio.2020.148213</a>","ieee":"M. J. W. Adjobo-Hermans <i>et al.</i>, “NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2,” <i>Biochimica et Biophysica Acta - Bioenergetics</i>, vol. 1861, no. 8. Elsevier, 2020.","apa":"Adjobo-Hermans, M. J. W., De Haas, R., Willems, P. H. G. M., Wojtala, A., Van Emst-De Vries, S. E., Wagenaars, J. A., … Koopman, W. J. H. (2020). NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. <i>Biochimica et Biophysica Acta - Bioenergetics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbabio.2020.148213\">https://doi.org/10.1016/j.bbabio.2020.148213</a>"},"article_type":"original","language":[{"iso":"eng"}],"scopus_import":"1","date_created":"2020-05-03T22:00:47Z","oa_version":"Published Version","publication":"Biochimica et Biophysica Acta - Bioenergetics","type":"journal_article","abstract":[{"text":"Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. To study the LS pathomechanism, we here compared OXPHOS proteomes between various Ndufs4−/− mouse tissues. Ndufs4−/− animals displayed significantly lower CI subunit levels in brain/diaphragm relative to other tissues (liver/heart/kidney/skeletal muscle), whereas other OXPHOS subunit levels were not reduced. Absence of NDUFS4 induced near complete absence of the NDUFA12 accessory subunit, a 50% reduction in other CI subunit levels, and an increase in specific CI assembly factors. Among the latter, NDUFAF2 was most highly increased. Regarding NDUFS4, NDUFA12 and NDUFAF2, identical results were obtained in Ndufs4−/− mouse embryonic fibroblasts (MEFs) and NDUFS4-mutated LS patient cells. Ndufs4−/− MEFs contained active CI in situ but blue-native-PAGE highlighted that NDUFAF2 attached to an inactive CI subcomplex (CI-830) and inactive assemblies of higher MW. In NDUFA12-mutated LS patient cells, NDUFA12 absence did not reduce NDUFS4 levels but triggered NDUFAF2 association to active CI. BN-PAGE revealed no such association in LS patient fibroblasts with mutations in other CI subunit-encoding genes where NDUFAF2 was attached to CI-830 (NDUFS1, NDUFV1 mutation) or not detected (NDUFS7 mutation). Supported by enzymological and CI in silico structural analysis, we conclude that absence of NDUFS4 induces near complete absence of NDUFA12 but not vice versa, and that NDUFAF2 stabilizes active CI in Ndufs4−/− mice and LS patient cells, perhaps in concert with mitochondrial inner membrane lipids.","lang":"eng"}],"has_accepted_license":"1","external_id":{"pmid":["32335026"],"isi":["000540842000012"]},"status":"public","intvolume":"      1861","date_updated":"2025-07-10T11:54:47Z","ddc":["570"],"pmid":1,"author":[{"last_name":"Adjobo-Hermans","first_name":"Merel J.W.","full_name":"Adjobo-Hermans, Merel J.W."},{"full_name":"De Haas, Ria","last_name":"De Haas","first_name":"Ria"},{"full_name":"Willems, Peter H.G.M.","last_name":"Willems","first_name":"Peter H.G.M."},{"full_name":"Wojtala, Aleksandra","last_name":"Wojtala","first_name":"Aleksandra"},{"full_name":"Van Emst-De Vries, Sjenet E.","last_name":"Van Emst-De Vries","first_name":"Sjenet E."},{"first_name":"Jori A.","last_name":"Wagenaars","full_name":"Wagenaars, Jori A."},{"last_name":"Van Den Brand","first_name":"Mariel","full_name":"Van Den Brand, Mariel"},{"full_name":"Rodenburg, Richard J.","last_name":"Rodenburg","first_name":"Richard J."},{"last_name":"Smeitink","first_name":"Jan A.M.","full_name":"Smeitink, Jan A.M."},{"last_name":"Nijtmans","first_name":"Leo G.","full_name":"Nijtmans, Leo G."},{"last_name":"Sazanov","orcid":"0000-0002-0977-7989","first_name":"Leonid A","full_name":"Sazanov, Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Wieckowski, Mariusz R.","first_name":"Mariusz R.","last_name":"Wieckowski"},{"full_name":"Koopman, Werner J.H.","last_name":"Koopman","first_name":"Werner J.H."}],"issue":"8","volume":1861,"month":"08","year":"2020","publication_status":"published","file_date_updated":"2020-07-14T12:48:03Z"},{"ddc":["570"],"date_updated":"2025-07-10T11:54:47Z","intvolume":"       181","external_id":{"pmid":["32259486"],"isi":["000530708400016"]},"status":"public","has_accepted_license":"1","abstract":[{"text":"During embryonic and postnatal development, organs and tissues grow steadily to achieve their final size at the end of puberty. However, little is known about the cellular dynamics that mediate postnatal growth. By combining in vivo clonal lineage tracing, proliferation kinetics, single-cell transcriptomics, andin vitro micro-pattern experiments, we resolved the cellular dynamics taking place during postnatal skin epidermis expansion. Our data revealed that harmonious growth is engineered by a single population of developmental progenitors presenting a fixed fate imbalance of self-renewing divisions with an ever-decreasing proliferation rate. Single-cell RNA sequencing revealed that epidermal developmental progenitors form a more uniform population compared with adult stem and progenitor cells. Finally, we found that the spatial pattern of cell division orientation is dictated locally by the underlying collagen fiber orientation. Our results uncover a simple design principle of organ growth where progenitors and differentiated cells expand in harmony with their surrounding tissues.","lang":"eng"}],"type":"journal_article","oa_version":"Published Version","date_created":"2020-05-03T22:00:48Z","scopus_import":"1","publication":"Cell","language":[{"iso":"eng"}],"citation":{"chicago":"Dekoninck, Sophie, Edouard B Hannezo, Alejandro Sifrim, Yekaterina A. Miroshnikova, Mariaceleste Aragona, Milan Malfait, Souhir Gargouri, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>.","short":"S. Dekoninck, E.B. Hannezo, A. Sifrim, Y.A. Miroshnikova, M. Aragona, M. Malfait, S. Gargouri, C. De Neunheuser, C. Dubois, T. Voet, S.A. Wickström, B.D. Simons, C. Blanpain, Cell 181 (2020) 604–620.e22.","mla":"Dekoninck, Sophie, et al. “Defining the Design Principles of Skin Epidermis Postnatal Growth.” <i>Cell</i>, vol. 181, no. 3, Elsevier, 2020, p. 604–620.e22, doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>.","ista":"Dekoninck S, Hannezo EB, Sifrim A, Miroshnikova YA, Aragona M, Malfait M, Gargouri S, De Neunheuser C, Dubois C, Voet T, Wickström SA, Simons BD, Blanpain C. 2020. Defining the design principles of skin epidermis postnatal growth. Cell. 181(3), 604–620.e22.","ama":"Dekoninck S, Hannezo EB, Sifrim A, et al. Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. 2020;181(3):604-620.e22. doi:<a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">10.1016/j.cell.2020.03.015</a>","ieee":"S. Dekoninck <i>et al.</i>, “Defining the design principles of skin epidermis postnatal growth,” <i>Cell</i>, vol. 181, no. 3. Elsevier, p. 604–620.e22, 2020.","apa":"Dekoninck, S., Hannezo, E. B., Sifrim, A., Miroshnikova, Y. A., Aragona, M., Malfait, M., … Blanpain, C. (2020). Defining the design principles of skin epidermis postnatal growth. <i>Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cell.2020.03.015\">https://doi.org/10.1016/j.cell.2020.03.015</a>"},"article_type":"original","file_date_updated":"2020-07-14T12:48:03Z","publication_status":"published","year":"2020","month":"04","volume":181,"issue":"3","author":[{"full_name":"Dekoninck, Sophie","last_name":"Dekoninck","first_name":"Sophie"},{"first_name":"Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B"},{"full_name":"Sifrim, Alejandro","last_name":"Sifrim","first_name":"Alejandro"},{"first_name":"Yekaterina A.","last_name":"Miroshnikova","full_name":"Miroshnikova, Yekaterina A."},{"first_name":"Mariaceleste","last_name":"Aragona","full_name":"Aragona, Mariaceleste"},{"last_name":"Malfait","first_name":"Milan","full_name":"Malfait, Milan"},{"last_name":"Gargouri","first_name":"Souhir","full_name":"Gargouri, Souhir"},{"full_name":"De Neunheuser, Charlotte","last_name":"De Neunheuser","first_name":"Charlotte"},{"last_name":"Dubois","first_name":"Christine","full_name":"Dubois, Christine"},{"full_name":"Voet, Thierry","first_name":"Thierry","last_name":"Voet"},{"first_name":"Sara A.","last_name":"Wickström","full_name":"Wickström, Sara A."},{"last_name":"Simons","first_name":"Benjamin D.","full_name":"Simons, Benjamin D."},{"full_name":"Blanpain, Cédric","last_name":"Blanpain","first_name":"Cédric"}],"page":"604-620.e22","pmid":1,"publisher":"Elsevier","doi":"10.1016/j.cell.2020.03.015","file":[{"date_created":"2020-05-04T10:20:55Z","content_type":"application/pdf","relation":"main_file","creator":"dernst","access_level":"open_access","checksum":"e2114902f4e9d75a752e9efb5ae06011","date_updated":"2020-07-14T12:48:03Z","file_id":"7795","file_name":"2020_Cell_Dekoninck.pdf","file_size":17992888}],"isi":1,"quality_controlled":"1","_id":"7789","date_published":"2020-04-30T00:00:00Z","title":"Defining the design principles of skin epidermis postnatal growth","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"EdHa"}],"day":"30","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"publication_identifier":{"issn":["0092-8674"],"eissn":["1097-4172"]},"article_processing_charge":"No"},{"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_identifier":{"eissn":["2050-5094"]},"article_processing_charge":"No","title":"The free energy of the two-dimensional dilute Bose gas. I. Lower bound","oa":1,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","department":[{"_id":"RoSe"}],"day":"14","article_number":"e20","_id":"7790","quality_controlled":"1","date_published":"2020-03-14T00:00:00Z","publisher":"Cambridge University Press","doi":"10.1017/fms.2020.17","file":[{"file_size":692530,"file_id":"7797","file_name":"2020_ForumMath_Deuchert.pdf","date_updated":"2020-07-14T12:48:03Z","checksum":"8a64da99d107686997876d7cad8cfe1e","access_level":"open_access","creator":"dernst","relation":"main_file","date_created":"2020-05-04T12:02:41Z","content_type":"application/pdf"}],"isi":1,"author":[{"full_name":"Deuchert, Andreas","id":"4DA65CD0-F248-11E8-B48F-1D18A9856A87","last_name":"Deuchert","orcid":"0000-0003-3146-6746","first_name":"Andreas"},{"full_name":"Mayer, Simon","id":"30C4630A-F248-11E8-B48F-1D18A9856A87","last_name":"Mayer","first_name":"Simon"},{"full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer"}],"publication_status":"published","file_date_updated":"2020-07-14T12:48:03Z","year":"2020","month":"03","volume":8,"related_material":{"record":[{"status":"public","id":"7524","relation":"earlier_version"}]},"status":"public","external_id":{"isi":["000527342000001"],"arxiv":["1910.03372"]},"has_accepted_license":"1","abstract":[{"text":"We prove a lower bound for the free energy (per unit volume) of the two-dimensional Bose gas in the thermodynamic limit. We show that the free energy at density 𝜌 and inverse temperature 𝛽 differs from the one of the noninteracting system by the correction term 𝜋𝜌𝜌𝛽𝛽 . Here, is the scattering length of the interaction potential, and 𝛽 is the inverse Berezinskii–Kosterlitz–Thouless critical temperature for superfluidity. The result is valid in the dilute limit 𝜌 and if 𝛽𝜌 .","lang":"eng"}],"type":"journal_article","corr_author":"1","date_created":"2020-05-03T22:00:48Z","scopus_import":"1","publication":"Forum of Mathematics, Sigma","oa_version":"Published Version","language":[{"iso":"eng"}],"citation":{"chicago":"Deuchert, Andreas, Simon Mayer, and Robert Seiringer. “The Free Energy of the Two-Dimensional Dilute Bose Gas. I. Lower Bound.” <i>Forum of Mathematics, Sigma</i>. Cambridge University Press, 2020. <a href=\"https://doi.org/10.1017/fms.2020.17\">https://doi.org/10.1017/fms.2020.17</a>.","short":"A. Deuchert, S. Mayer, R. Seiringer, Forum of Mathematics, Sigma 8 (2020).","mla":"Deuchert, Andreas, et al. “The Free Energy of the Two-Dimensional Dilute Bose Gas. I. Lower Bound.” <i>Forum of Mathematics, Sigma</i>, vol. 8, e20, Cambridge University Press, 2020, doi:<a href=\"https://doi.org/10.1017/fms.2020.17\">10.1017/fms.2020.17</a>.","ama":"Deuchert A, Mayer S, Seiringer R. The free energy of the two-dimensional dilute Bose gas. I. Lower bound. <i>Forum of Mathematics, Sigma</i>. 2020;8. doi:<a href=\"https://doi.org/10.1017/fms.2020.17\">10.1017/fms.2020.17</a>","ieee":"A. Deuchert, S. Mayer, and R. Seiringer, “The free energy of the two-dimensional dilute Bose gas. I. Lower bound,” <i>Forum of Mathematics, Sigma</i>, vol. 8. Cambridge University Press, 2020.","ista":"Deuchert A, Mayer S, Seiringer R. 2020. The free energy of the two-dimensional dilute Bose gas. I. Lower bound. Forum of Mathematics, Sigma. 8, e20.","apa":"Deuchert, A., Mayer, S., &#38; Seiringer, R. (2020). The free energy of the two-dimensional dilute Bose gas. I. Lower bound. <i>Forum of Mathematics, Sigma</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/fms.2020.17\">https://doi.org/10.1017/fms.2020.17</a>"},"ec_funded":1,"article_type":"original","arxiv":1,"ddc":["510"],"date_updated":"2026-04-03T09:30:21Z","intvolume":"         8","project":[{"grant_number":"694227","call_identifier":"H2020","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","name":"Analysis of quantum many-body systems"}]},{"month":"09","volume":19,"publication_status":"published","year":"2020","page":"964–968","pmid":1,"author":[{"first_name":"Javier","last_name":"Taboada-Gutiérrez","full_name":"Taboada-Gutiérrez, Javier"},{"full_name":"Álvarez-Pérez, Gonzalo","last_name":"Álvarez-Pérez","first_name":"Gonzalo"},{"last_name":"Duan","first_name":"Jiahua","full_name":"Duan, Jiahua"},{"full_name":"Ma, Weiliang","first_name":"Weiliang","last_name":"Ma"},{"full_name":"Crowley, Kyle","last_name":"Crowley","first_name":"Kyle"},{"full_name":"Prieto Gonzalez, Ivan","id":"2A307FE2-F248-11E8-B48F-1D18A9856A87","last_name":"Prieto Gonzalez","orcid":"0000-0002-7370-5357","first_name":"Ivan"},{"full_name":"Bylinkin, Andrei","first_name":"Andrei","last_name":"Bylinkin"},{"full_name":"Autore, Marta","last_name":"Autore","first_name":"Marta"},{"last_name":"Volkova","first_name":"Halyna","full_name":"Volkova, Halyna"},{"first_name":"Kenta","last_name":"Kimura","full_name":"Kimura, Kenta"},{"last_name":"Kimura","first_name":"Tsuyoshi","full_name":"Kimura, Tsuyoshi"},{"first_name":"M. H.","last_name":"Berger","full_name":"Berger, M. H."},{"full_name":"Li, Shaojuan","first_name":"Shaojuan","last_name":"Li"},{"first_name":"Qiaoliang","last_name":"Bao","full_name":"Bao, Qiaoliang"},{"last_name":"Gao","first_name":"Xuan P.A.","full_name":"Gao, Xuan P.A."},{"first_name":"Ion","last_name":"Errea","full_name":"Errea, Ion"},{"full_name":"Nikitin, Alexey Y.","first_name":"Alexey Y.","last_name":"Nikitin"},{"first_name":"Rainer","last_name":"Hillenbrand","full_name":"Hillenbrand, Rainer"},{"full_name":"Martín-Sánchez, Javier","first_name":"Javier","last_name":"Martín-Sánchez"},{"last_name":"Alonso-González","first_name":"Pablo","full_name":"Alonso-González, Pablo"}],"OA_type":"green","date_updated":"2025-04-23T14:24:58Z","arxiv":1,"OA_place":"repository","intvolume":"        19","article_type":"original","citation":{"chicago":"Taboada-Gutiérrez, Javier, Gonzalo Álvarez-Pérez, Jiahua Duan, Weiliang Ma, Kyle Crowley, Ivan Prieto Gonzalez, Andrei Bylinkin, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>.","ama":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, et al. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. 2020;19:964–968. doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>","ieee":"J. Taboada-Gutiérrez <i>et al.</i>, “Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation,” <i>Nature Materials</i>, vol. 19. Springer Nature, pp. 964–968, 2020.","ista":"Taboada-Gutiérrez J, Álvarez-Pérez G, Duan J, Ma W, Crowley K, Prieto Gonzalez I, Bylinkin A, Autore M, Volkova H, Kimura K, Kimura T, Berger MH, Li S, Bao Q, Gao XPA, Errea I, Nikitin AY, Hillenbrand R, Martín-Sánchez J, Alonso-González P. 2020. Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. Nature Materials. 19, 964–968.","apa":"Taboada-Gutiérrez, J., Álvarez-Pérez, G., Duan, J., Ma, W., Crowley, K., Prieto Gonzalez, I., … Alonso-González, P. (2020). Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation. <i>Nature Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41563-020-0665-0\">https://doi.org/10.1038/s41563-020-0665-0</a>","short":"J. Taboada-Gutiérrez, G. Álvarez-Pérez, J. Duan, W. Ma, K. Crowley, I. Prieto Gonzalez, A. Bylinkin, M. Autore, H. Volkova, K. Kimura, T. Kimura, M.H. Berger, S. Li, Q. Bao, X.P.A. Gao, I. Errea, A.Y. Nikitin, R. Hillenbrand, J. Martín-Sánchez, P. Alonso-González, Nature Materials 19 (2020) 964–968.","mla":"Taboada-Gutiérrez, Javier, et al. “Broad Spectral Tuning of Ultra-Low-Loss Polaritons in a van Der Waals Crystal by Intercalation.” <i>Nature Materials</i>, vol. 19, Springer Nature, 2020, pp. 964–968, doi:<a href=\"https://doi.org/10.1038/s41563-020-0665-0\">10.1038/s41563-020-0665-0</a>."},"language":[{"iso":"eng"}],"abstract":[{"text":"Phonon polaritons—light coupled to lattice vibrations—in polar van der Waals crystals are promising candidates for controlling the flow of energy on the nanoscale due to their strong field confinement, anisotropic propagation and ultra-long lifetime in the picosecond range1,2,3,4,5. However, the lack of tunability of their narrow and material-specific spectral range—the Reststrahlen band—severely limits their technological implementation. Here, we demonstrate that intercalation of Na atoms in the van der Waals semiconductor α-V2O5 enables a broad spectral shift of Reststrahlen bands, and that the phonon polaritons excited show ultra-low losses (lifetime of 4 ± 1 ps), similar to phonon polaritons in a non-intercalated crystal (lifetime of 6 ± 1 ps). We expect our intercalation method to be applicable to other van der Waals crystals, opening the door for the use of phonon polaritons in broad spectral bands in the mid-infrared domain.","lang":"eng"}],"external_id":{"arxiv":["2501.08705"],"pmid":["32284598"],"isi":["000526218500004"]},"status":"public","publication":"Nature Materials","date_created":"2020-05-03T22:00:49Z","scopus_import":"1","oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2501.08705","open_access":"1"}],"type":"journal_article","department":[{"_id":"NanoFab"}],"day":"01","oa":1,"title":"Broad spectral tuning of ultra-low-loss polaritons in a van der Waals crystal by intercalation","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1476-4660"],"issn":["1476-1122"]},"article_processing_charge":"No","publisher":"Springer Nature","acknowledgement":"J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa Program from the Government of the Principality of Asturias (nos. PA-18-PF-BP17-126 and PA-20-PF-BP19-053, respectively). J.M.-S. acknowledges finantial support from the Clarín Programme from the Government of the Principality of Asturias and a Marie Curie-COFUND grant (PA-18-ACB17-29) and the Ramón y Cajal Program from the Government of Spain (RYC2018-026196-I). K.C., X.P.A.G., H.V. and M.H.B. acknowledge the Air Force Office of Scientific Research (AFOSR) grant no. FA 9550-18-1-0030 for funding support. I.E. acknowledges financial support from the Spanish Ministry of Economy and Competitiveness (grant no. FIS2016-76617-P). A.Y.N. acknowledges the Spanish Ministry of Science, Innovation and Universities (national project no. MAT2017-88358-C3-3-R) and the Basque Government (grant no. IT1164-19). Q.B. acknowledges the support from Australian Research Council (grant nos. FT150100450, IH150100006 and CE170100039). R.H. acknowledges support from the Spanish Ministry of Economy, Industry, and Competitiveness (national project RTI2018-094830-B-100 and the Project MDM-2016-0618 of the María de Maeztu Units of Excellence Program) and the Basque Goverment (grant no. IT1164-19). P.A.-G. acknowledges support from the European Research Council under starting grant no. 715496, 2DNANOPTICA.","doi":"10.1038/s41563-020-0665-0","isi":1,"_id":"7792","quality_controlled":"1","date_published":"2020-09-01T00:00:00Z"}]
