[{"oa":1,"date_published":"2018-06-06T00:00:00Z","month":"06","language":[{"iso":"eng"}],"date_updated":"2023-09-13T07:38:24Z","publisher":"Neural Information Processing Systems Foundation","department":[{"_id":"FrLo"}],"arxiv":1,"oa_version":"Preprint","intvolume":"        31","type":"conference","scopus_import":"1","_id":"14202","citation":{"short":"F. Locatello, G. Dresdner, R. Khanna, I. Valera, G. Rätsch, in:, Advances in Neural Information Processing Systems, Neural Information Processing Systems Foundation, 2018.","ieee":"F. Locatello, G. Dresdner, R. Khanna, I. Valera, and G. Rätsch, “Boosting black box variational inference,” in <i>Advances in Neural Information Processing Systems</i>, Montreal, Canada, 2018, vol. 31.","ista":"Locatello F, Dresdner G, Khanna R, Valera I, Rätsch G. 2018. Boosting black box variational inference. Advances in Neural Information Processing Systems. NeurIPS: Neural Information Processing Systems vol. 31.","ama":"Locatello F, Dresdner G, Khanna R, Valera I, Rätsch G. Boosting black box variational inference. In: <i>Advances in Neural Information Processing Systems</i>. Vol 31. Neural Information Processing Systems Foundation; 2018.","apa":"Locatello, F., Dresdner, G., Khanna, R., Valera, I., &#38; Rätsch, G. (2018). Boosting black box variational inference. In <i>Advances in Neural Information Processing Systems</i> (Vol. 31). Montreal, Canada: Neural Information Processing Systems Foundation.","chicago":"Locatello, Francesco, Gideon Dresdner, Rajiv Khanna, Isabel Valera, and Gunnar Rätsch. “Boosting Black Box Variational Inference.” In <i>Advances in Neural Information Processing Systems</i>, Vol. 31. Neural Information Processing Systems Foundation, 2018.","mla":"Locatello, Francesco, et al. “Boosting Black Box Variational Inference.” <i>Advances in Neural Information Processing Systems</i>, vol. 31, Neural Information Processing Systems Foundation, 2018."},"day":"06","status":"public","article_processing_charge":"No","external_id":{"arxiv":["1806.02185"]},"publication_status":"published","abstract":[{"text":"Approximating a probability density in a tractable manner is a central task\r\nin Bayesian statistics. Variational Inference (VI) is a popular technique that\r\nachieves tractability by choosing a relatively simple variational family.\r\nBorrowing ideas from the classic boosting framework, recent approaches attempt\r\nto \\emph{boost} VI by replacing the selection of a single density with a\r\ngreedily constructed mixture of densities. In order to guarantee convergence,\r\nprevious works impose stringent assumptions that require significant effort for\r\npractitioners. Specifically, they require a custom implementation of the greedy\r\nstep (called the LMO) for every probabilistic model with respect to an\r\nunnatural variational family of truncated distributions. Our work fixes these\r\nissues with novel theoretical and algorithmic insights. On the theoretical\r\nside, we show that boosting VI satisfies a relaxed smoothness assumption which\r\nis sufficient for the convergence of the functional Frank-Wolfe (FW) algorithm.\r\nFurthermore, we rephrase the LMO problem and propose to maximize the Residual\r\nELBO (RELBO) which replaces the standard ELBO optimization in VI. These\r\ntheoretical enhancements allow for black box implementation of the boosting\r\nsubroutine. Finally, we present a stopping criterion drawn from the duality gap\r\nin the classic FW analyses and exhaustive experiments to illustrate the\r\nusefulness of our theoretical and algorithmic contributions.","lang":"eng"}],"title":"Boosting black box variational inference","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Locatello, Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683","first_name":"Francesco","last_name":"Locatello"},{"full_name":"Dresdner, Gideon","last_name":"Dresdner","first_name":"Gideon"},{"first_name":"Rajiv","last_name":"Khanna","full_name":"Khanna, Rajiv"},{"last_name":"Valera","first_name":"Isabel","full_name":"Valera, Isabel"},{"full_name":"Rätsch, Gunnar","first_name":"Gunnar","last_name":"Rätsch"}],"extern":"1","volume":31,"quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1806.02185"}],"conference":{"end_date":"2018-12-08","location":"Montreal, Canada","start_date":"2018-12-03","name":"NeurIPS: Neural Information Processing Systems"},"date_created":"2023-08-22T14:15:40Z","year":"2018","publication_identifier":{"isbn":["9781510884472"],"eissn":["1049-5258"]},"publication":"Advances in Neural Information Processing Systems"},{"publication":"Proceedings of the 35th International Conference on Machine Learning","year":"2018","date_created":"2023-08-22T14:16:01Z","conference":{"name":"ICML: International Conference on Machine Learning","start_date":"2018-07-10","end_date":"2018-07-15","location":"Stockholm, Sweden"},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1804.08544"}],"quality_controlled":"1","volume":80,"extern":"1","author":[{"full_name":"Yurtsever, Alp","last_name":"Yurtsever","first_name":"Alp"},{"last_name":"Fercoq","first_name":"Olivier","full_name":"Fercoq, Olivier"},{"first_name":"Francesco","last_name":"Locatello","full_name":"Locatello, Francesco","orcid":"0000-0002-4850-0683","id":"26cfd52f-2483-11ee-8040-88983bcc06d4"},{"first_name":"Volkan","last_name":"Cevher","full_name":"Cevher, Volkan"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"A conditional gradient framework for composite convex minimization with applications to semidefinite programming","abstract":[{"text":"We propose a conditional gradient framework for a composite convex minimization template with broad applications. Our approach combines smoothing and homotopy techniques under the CGM framework, and provably achieves the optimal O(1/k−−√) convergence rate. We demonstrate that the same rate holds if the linear subproblems are solved approximately with additive or multiplicative error. In contrast with the relevant work, we are able to characterize the convergence when the non-smooth term is an indicator function. Specific applications of our framework include the non-smooth minimization, semidefinite programming, and minimization with linear inclusion constraints over a compact domain. Numerical evidence demonstrates the benefits of our framework.","lang":"eng"}],"publication_status":"published","external_id":{"arxiv":["1804.08544"]},"page":"5727-5736","article_processing_charge":"No","day":"15","status":"public","alternative_title":["PMLR"],"citation":{"apa":"Yurtsever, A., Fercoq, O., Locatello, F., &#38; Cevher, V. (2018). A conditional gradient framework for composite convex minimization with applications to semidefinite programming. In <i>Proceedings of the 35th International Conference on Machine Learning</i> (Vol. 80, pp. 5727–5736). Stockholm, Sweden: ML Research Press.","chicago":"Yurtsever, Alp, Olivier Fercoq, Francesco Locatello, and Volkan Cevher. “A Conditional Gradient Framework for Composite Convex Minimization with Applications to Semidefinite Programming.” In <i>Proceedings of the 35th International Conference on Machine Learning</i>, 80:5727–36. ML Research Press, 2018.","mla":"Yurtsever, Alp, et al. “A Conditional Gradient Framework for Composite Convex Minimization with Applications to Semidefinite Programming.” <i>Proceedings of the 35th International Conference on Machine Learning</i>, vol. 80, ML Research Press, 2018, pp. 5727–36.","short":"A. Yurtsever, O. Fercoq, F. Locatello, V. Cevher, in:, Proceedings of the 35th International Conference on Machine Learning, ML Research Press, 2018, pp. 5727–5736.","ieee":"A. Yurtsever, O. Fercoq, F. Locatello, and V. Cevher, “A conditional gradient framework for composite convex minimization with applications to semidefinite programming,” in <i>Proceedings of the 35th International Conference on Machine Learning</i>, Stockholm, Sweden, 2018, vol. 80, pp. 5727–5736.","ista":"Yurtsever A, Fercoq O, Locatello F, Cevher V. 2018. A conditional gradient framework for composite convex minimization with applications to semidefinite programming. Proceedings of the 35th International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 80, 5727–5736.","ama":"Yurtsever A, Fercoq O, Locatello F, Cevher V. A conditional gradient framework for composite convex minimization with applications to semidefinite programming. In: <i>Proceedings of the 35th International Conference on Machine Learning</i>. Vol 80. ML Research Press; 2018:5727-5736."},"_id":"14203","type":"conference","oa_version":"Preprint","intvolume":"        80","department":[{"_id":"FrLo"}],"arxiv":1,"publisher":"ML Research Press","date_updated":"2023-09-13T08:13:39Z","language":[{"iso":"eng"}],"month":"07","date_published":"2018-07-15T00:00:00Z","oa":1},{"citation":{"apa":"Locatello, F., Raj, A., Karimireddy, S. P., Rätsch, G., Schölkopf, B., Stich, S. U., &#38; Jaggi, M. (2018). On matching pursuit and coordinate descent. In <i>Proceedings of the 35th International Conference on Machine Learning</i> (Vol. 80, pp. 3198–3207). ML Research Press.","chicago":"Locatello, Francesco, Anant Raj, Sai Praneeth Karimireddy, Gunnar Rätsch, Bernhard Schölkopf, Sebastian U. Stich, and Martin Jaggi. “On Matching Pursuit and Coordinate Descent.” In <i>Proceedings of the 35th International Conference on Machine Learning</i>, 80:3198–3207. ML Research Press, 2018.","mla":"Locatello, Francesco, et al. “On Matching Pursuit and Coordinate Descent.” <i>Proceedings of the 35th International Conference on Machine Learning</i>, vol. 80, ML Research Press, 2018, pp. 3198–207.","ieee":"F. Locatello <i>et al.</i>, “On matching pursuit and coordinate descent,” in <i>Proceedings of the 35th International Conference on Machine Learning</i>, 2018, vol. 80, pp. 3198–3207.","short":"F. Locatello, A. Raj, S.P. Karimireddy, G. Rätsch, B. Schölkopf, S.U. Stich, M. Jaggi, in:, Proceedings of the 35th International Conference on Machine Learning, ML Research Press, 2018, pp. 3198–3207.","ama":"Locatello F, Raj A, Karimireddy SP, et al. On matching pursuit and coordinate descent. In: <i>Proceedings of the 35th International Conference on Machine Learning</i>. Vol 80. ML Research Press; 2018:3198-3207.","ista":"Locatello F, Raj A, Karimireddy SP, Rätsch G, Schölkopf B, Stich SU, Jaggi M. 2018. On matching pursuit and coordinate descent. Proceedings of the 35th International Conference on Machine Learning. , PMLR, vol. 80, 3198–3207."},"alternative_title":["PMLR"],"status":"public","day":"01","oa":1,"date_published":"2018-07-01T00:00:00Z","language":[{"iso":"eng"}],"month":"07","date_updated":"2024-10-14T12:29:40Z","publisher":"ML Research Press","arxiv":1,"department":[{"_id":"FrLo"}],"intvolume":"        80","oa_version":"Preprint","type":"conference","scopus_import":"1","_id":"14204","quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/1803.09539","open_access":"1"}],"date_created":"2023-08-22T14:16:25Z","year":"2018","publication":"Proceedings of the 35th International Conference on Machine Learning","article_processing_charge":"No","page":"3198-3207","external_id":{"arxiv":["1803.09539"]},"publication_status":"published","abstract":[{"text":"Two popular examples of first-order optimization methods over linear spaces are coordinate descent and matching pursuit algorithms, with their randomized variants. While the former targets the optimization by moving along coordinates, the latter considers a generalized notion of directions. Exploiting the connection between the two algorithms, we present a unified analysis of both, providing affine invariant sublinear O(1/t) rates on smooth objectives and linear convergence on strongly convex objectives. As a byproduct of our affine invariant analysis of matching pursuit, our rates for steepest coordinate descent are the tightest known. Furthermore, we show the first accelerated convergence rate O(1/t2) for matching pursuit and steepest coordinate descent on convex objectives.","lang":"eng"}],"title":"On matching pursuit and coordinate descent","author":[{"first_name":"Francesco","last_name":"Locatello","full_name":"Locatello, Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683"},{"first_name":"Anant","last_name":"Raj","full_name":"Raj, Anant"},{"full_name":"Karimireddy, Sai Praneeth","last_name":"Karimireddy","first_name":"Sai Praneeth"},{"last_name":"Rätsch","first_name":"Gunnar","full_name":"Rätsch, Gunnar"},{"full_name":"Schölkopf, Bernhard","last_name":"Schölkopf","first_name":"Bernhard"},{"full_name":"Stich, Sebastian U.","first_name":"Sebastian U.","last_name":"Stich"},{"last_name":"Jaggi","first_name":"Martin","full_name":"Jaggi, Martin"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","volume":80},{"year":"2018","date_created":"2023-08-22T14:25:34Z","publication":"6th International Conference on Learning Representations","day":"01","status":"public","quality_controlled":"1","citation":{"chicago":"Locatello, Francesco, Damien Vincent, Ilya Tolstikhin, Gunnar Ratsch, Sylvain Gelly, and Bernhard Scholkopf. “Clustering Meets Implicit Generative Models.” In <i>6th International Conference on Learning Representations</i>, 2018.","apa":"Locatello, F., Vincent, D., Tolstikhin, I., Ratsch, G., Gelly, S., &#38; Scholkopf, B. (2018). Clustering meets implicit generative models. In <i>6th International Conference on Learning Representations</i>. Vancouver, Canada.","mla":"Locatello, Francesco, et al. “Clustering Meets Implicit Generative Models.” <i>6th International Conference on Learning Representations</i>, 2018.","ieee":"F. Locatello, D. Vincent, I. Tolstikhin, G. Ratsch, S. Gelly, and B. Scholkopf, “Clustering meets implicit generative models,” in <i>6th International Conference on Learning Representations</i>, Vancouver, Canada, 2018.","short":"F. Locatello, D. Vincent, I. Tolstikhin, G. Ratsch, S. Gelly, B. Scholkopf, in:, 6th International Conference on Learning Representations, 2018.","ista":"Locatello F, Vincent D, Tolstikhin I, Ratsch G, Gelly S, Scholkopf B. 2018. Clustering meets implicit generative models. 6th International Conference on Learning Representations. International Conference on Machine Learning.","ama":"Locatello F, Vincent D, Tolstikhin I, Ratsch G, Gelly S, Scholkopf B. Clustering meets implicit generative models. In: <i>6th International Conference on Learning Representations</i>. ; 2018."},"conference":{"start_date":"2018-04-30","name":"International Conference on Machine Learning","location":"Vancouver, Canada","end_date":"2018-05-03"},"main_file_link":[{"url":"https://arxiv.org/abs/1804.11130","open_access":"1"}],"type":"conference","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Francesco","last_name":"Locatello","full_name":"Locatello, Francesco","orcid":"0000-0002-4850-0683","id":"26cfd52f-2483-11ee-8040-88983bcc06d4"},{"last_name":"Vincent","first_name":"Damien","full_name":"Vincent, Damien"},{"full_name":"Tolstikhin, Ilya","last_name":"Tolstikhin","first_name":"Ilya"},{"full_name":"Ratsch, Gunnar","first_name":"Gunnar","last_name":"Ratsch"},{"first_name":"Sylvain","last_name":"Gelly","full_name":"Gelly, Sylvain"},{"full_name":"Scholkopf, Bernhard","last_name":"Scholkopf","first_name":"Bernhard"}],"oa_version":"Preprint","_id":"14224","scopus_import":"1","abstract":[{"text":"Clustering is a cornerstone of unsupervised learning which can be thought as disentangling multiple generative mechanisms underlying the data. In this paper we introduce an algorithmic framework to train mixtures of implicit generative models which we particularize for variational autoencoders. Relying on an additional set of discriminators, we propose a competitive procedure in which the models only need to approximate the portion of the data distribution from which they can produce realistic samples. As a byproduct, each model is simpler to train, and a clustering interpretation arises naturally from the partitioning of the training points among the models. We empirically show that our approach splits the training distribution in a reasonable way and increases the quality of the generated samples.","lang":"eng"}],"oa":1,"external_id":{"arxiv":["1804.11130"]},"publication_status":"published","article_processing_charge":"No","arxiv":1,"department":[{"_id":"FrLo"}],"date_updated":"2024-10-14T12:30:32Z","language":[{"iso":"eng"}],"month":"05","title":"Clustering meets implicit generative models","date_published":"2018-05-01T00:00:00Z"},{"month":"05","language":[{"iso":"eng"}],"date_published":"2018-05-04T00:00:00Z","publisher":"Springer Nature","date_updated":"2023-11-07T11:46:12Z","oa":1,"_id":"14284","scopus_import":"1","article_type":"original","oa_version":"Published Version","intvolume":"         9","type":"journal_article","citation":{"apa":"Bräuning, B., Bertosin, E., Praetorius, F. M., Ihling, C., Schatt, A., Adler, A., … Groll, M. (2018). Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-018-04139-2\">https://doi.org/10.1038/s41467-018-04139-2</a>","chicago":"Bräuning, Bastian, Eva Bertosin, Florian M Praetorius, Christian Ihling, Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, and Michael Groll. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” <i>Nature Communications</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41467-018-04139-2\">https://doi.org/10.1038/s41467-018-04139-2</a>.","mla":"Bräuning, Bastian, et al. “Structure and Mechanism of the Two-Component α-Helical Pore-Forming Toxin YaxAB.” <i>Nature Communications</i>, vol. 9, 1806, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-04139-2\">10.1038/s41467-018-04139-2</a>.","short":"B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).","ieee":"B. Bräuning <i>et al.</i>, “Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB,” <i>Nature Communications</i>, vol. 9. Springer Nature, 2018.","ista":"Bräuning B, Bertosin E, Praetorius FM, Ihling C, Schatt A, Adler A, Richter K, Sinz A, Dietz H, Groll M. 2018. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Nature Communications. 9, 1806.","ama":"Bräuning B, Bertosin E, Praetorius FM, et al. Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. <i>Nature Communications</i>. 2018;9. doi:<a href=\"https://doi.org/10.1038/s41467-018-04139-2\">10.1038/s41467-018-04139-2</a>"},"status":"public","day":"04","title":"Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB","keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. YaxAB was shown to be cytotoxic and likely involved in pathogenesis, though the molecular basis for its two-component lytic mechanism remains elusive. Here, we present crystal structures of YaxA and YaxB, together with a cryo-electron microscopy map of the YaxAB complex. Our structures reveal a pore predominantly composed of decamers of YaxA–YaxB heterodimers. Both subunits bear membrane-active moieties, but only YaxA is capable of binding to membranes by itself. YaxB can subsequently be recruited to membrane-associated YaxA and induced to present its lytic transmembrane helices. Pore formation can progress by further oligomerization of YaxA–YaxB dimers. Our results allow for a comparison between pore assemblies belonging to the wider ClyA-like family of α-PFTs, highlighting diverse pore architectures."}],"external_id":{"pmid":["29728606"]},"publication_status":"published","pmid":1,"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Bräuning, Bastian","last_name":"Bräuning","first_name":"Bastian"},{"full_name":"Bertosin, Eva","last_name":"Bertosin","first_name":"Eva"},{"full_name":"Praetorius, Florian M","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","first_name":"Florian M","last_name":"Praetorius"},{"full_name":"Ihling, Christian","first_name":"Christian","last_name":"Ihling"},{"first_name":"Alexandra","last_name":"Schatt","full_name":"Schatt, Alexandra"},{"full_name":"Adler, Agnes","last_name":"Adler","first_name":"Agnes"},{"last_name":"Richter","first_name":"Klaus","full_name":"Richter, Klaus"},{"first_name":"Andrea","last_name":"Sinz","full_name":"Sinz, Andrea"},{"full_name":"Dietz, Hendrik","last_name":"Dietz","first_name":"Hendrik"},{"first_name":"Michael","last_name":"Groll","full_name":"Groll, Michael"}],"volume":9,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-018-04139-2"}],"quality_controlled":"1","publication_identifier":{"issn":["2041-1723"]},"doi":"10.1038/s41467-018-04139-2","publication":"Nature Communications","year":"2018","date_created":"2023-09-06T12:07:33Z","article_number":"1806"},{"date_created":"2018-12-11T11:44:51Z","year":"2018","publication_identifier":{"isbn":["978-1-4503-5583-4"]},"doi":"10.1145/3209108.3209191","quality_controlled":"1","conference":{"end_date":"2018-07-12","location":"Oxford, United Kingdom","start_date":"2018-07-09","name":"LICS: Logic in Computer Science"},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1804.10985"}],"volume":"F138033","author":[{"last_name":"Brázdil","first_name":"Tomáš","full_name":"Brázdil, Tomáš"},{"orcid":"0000-0002-4561-241X","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu","last_name":"Chatterjee"},{"first_name":"Antonín","last_name":"Kučera","full_name":"Kučera, Antonín"},{"first_name":"Petr","last_name":"Novotny","id":"3CC3B868-F248-11E8-B48F-1D18A9856A87","full_name":"Novotny, Petr"},{"full_name":"Velan, Dominik","last_name":"Velan","first_name":"Dominik"},{"last_name":"Zuleger","first_name":"Florian","full_name":"Zuleger, Florian"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","external_id":{"arxiv":["1804.10985"],"isi":["000545262800020"]},"abstract":[{"text":"Vector Addition Systems with States (VASS) provide a well-known and fundamental model for the analysis of concurrent processes, parameterized systems, and are also used as abstract models of programs in resource bound analysis. In this paper we study the problem of obtaining asymptotic bounds on the termination time of a given VASS. In particular, we focus on the practically important case of obtaining polynomial bounds on termination time. Our main contributions are as follows: First, we present a polynomial-time algorithm for deciding whether a given VASS has a linear asymptotic complexity. We also show that if the complexity of a VASS is not linear, it is at least quadratic. Second, we classify VASS according to quantitative properties of their cycles. We show that certain singularities in these properties are the key reason for non-polynomial asymptotic complexity of VASS. In absence of singularities, we show that the asymptotic complexity is always polynomial and of the form Θ(nk), for some integer k d, where d is the dimension of the VASS. We present a polynomial-time algorithm computing the optimal k. For general VASS, the same algorithm, which is based on a complete technique for the construction of ranking functions in VASS, produces a valid lower bound, i.e., a k such that the termination complexity is (nk). Our results are based on new insights into the geometry of VASS dynamics, which hold the potential for further applicability to VASS analysis.","lang":"eng"}],"article_processing_charge":"No","page":"185 - 194","title":"Efficient algorithms for asymptotic bounds on termination time in VASS","ec_funded":1,"day":"09","status":"public","alternative_title":["ACM/IEEE Symposium on Logic in Computer Science"],"project":[{"name":"Efficient Algorithms for Computer Aided Verification","_id":"25892FC0-B435-11E9-9278-68D0E5697425","grant_number":"ICT15-003"},{"call_identifier":"FP7","name":"Quantitative Graph Games: Theory and Applications","_id":"2581B60A-B435-11E9-9278-68D0E5697425","grant_number":"279307"},{"grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering","call_identifier":"FWF"}],"citation":{"ista":"Brázdil T, Chatterjee K, Kučera A, Novotný P, Velan D, Zuleger F. 2018. Efficient algorithms for asymptotic bounds on termination time in VASS. LICS: Logic in Computer Science, ACM/IEEE Symposium on Logic in Computer Science, vol. F138033, 185–194.","ama":"Brázdil T, Chatterjee K, Kučera A, Novotný P, Velan D, Zuleger F. Efficient algorithms for asymptotic bounds on termination time in VASS. In: Vol F138033. IEEE; 2018:185-194. doi:<a href=\"https://doi.org/10.1145/3209108.3209191\">10.1145/3209108.3209191</a>","ieee":"T. Brázdil, K. Chatterjee, A. Kučera, P. Novotný, D. Velan, and F. Zuleger, “Efficient algorithms for asymptotic bounds on termination time in VASS,” presented at the LICS: Logic in Computer Science, Oxford, United Kingdom, 2018, vol. F138033, pp. 185–194.","short":"T. Brázdil, K. Chatterjee, A. Kučera, P. Novotný, D. Velan, F. Zuleger, in:, IEEE, 2018, pp. 185–194.","mla":"Brázdil, Tomáš, et al. <i>Efficient Algorithms for Asymptotic Bounds on Termination Time in VASS</i>. Vol. F138033, IEEE, 2018, pp. 185–94, doi:<a href=\"https://doi.org/10.1145/3209108.3209191\">10.1145/3209108.3209191</a>.","chicago":"Brázdil, Tomáš, Krishnendu Chatterjee, Antonín Kučera, Petr Novotný, Dominik Velan, and Florian Zuleger. “Efficient Algorithms for Asymptotic Bounds on Termination Time in VASS,” F138033:185–94. IEEE, 2018. <a href=\"https://doi.org/10.1145/3209108.3209191\">https://doi.org/10.1145/3209108.3209191</a>.","apa":"Brázdil, T., Chatterjee, K., Kučera, A., Novotný, P., Velan, D., &#38; Zuleger, F. (2018). Efficient algorithms for asymptotic bounds on termination time in VASS (Vol. F138033, pp. 185–194). Presented at the LICS: Logic in Computer Science, Oxford, United Kingdom: IEEE. <a href=\"https://doi.org/10.1145/3209108.3209191\">https://doi.org/10.1145/3209108.3209191</a>"},"type":"conference","oa_version":"Preprint","scopus_import":"1","_id":"143","publist_id":"7780","oa":1,"isi":1,"date_updated":"2025-06-04T08:04:55Z","arxiv":1,"department":[{"_id":"KrCh"}],"publisher":"IEEE","date_published":"2018-07-09T00:00:00Z","month":"07","language":[{"iso":"eng"}]},{"citation":{"mla":"Praetorius, Florian M. <i>Genetically Encoding the Spatial Arrangement of DNA and Proteins in Self-Assembling Nanostructures</i>. Technische Universität München, 2018.","chicago":"Praetorius, Florian M. “Genetically Encoding the Spatial Arrangement of DNA and Proteins in Self-Assembling Nanostructures.” Technische Universität München, 2018.","apa":"Praetorius, F. M. (2018). <i>Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures</i>. Technische Universität München.","ama":"Praetorius FM. Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures. 2018.","ista":"Praetorius FM. 2018. Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures. Technische Universität München.","short":"F.M. Praetorius, Genetically Encoding the Spatial Arrangement of DNA and Proteins in Self-Assembling Nanostructures, Technische Universität München, 2018.","ieee":"F. M. Praetorius, “Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures,” Technische Universität München, 2018."},"main_file_link":[{"url":"https://mediatum.ub.tum.de/1398662","open_access":"1"}],"year":"2018","date_created":"2023-09-06T13:11:22Z","day":"16","status":"public","article_processing_charge":"No","oa":1,"abstract":[{"lang":"eng","text":"Function and activity of biomolecules often depend on their spatial arrangement. The method introduced here allows genetically encoding the spatial arrangement of proteins and DNA. The approach relies on staple proteins that fold double-stranded DNA into user-defined shapes. This thesis describes the development of staple proteins based on the DNA recognition of TAL effectors and presents experimentally derived rules for designing a variety of self-assembling nanoscale shapes featuring structural motifs such as curvature, vertices, corners, and multilayer helix packing. "}],"publication_status":"published","language":[{"iso":"eng"}],"month":"01","degree_awarded":"PhD","title":"Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures","supervisor":[{"full_name":"Dietz, Hendrik","last_name":"Dietz","first_name":"Hendrik"}],"date_published":"2018-01-16T00:00:00Z","publisher":"Technische Universität München","date_updated":"2024-10-14T12:31:46Z","extern":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Florian M","last_name":"Praetorius","full_name":"Praetorius, Florian M","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62"}],"type":"dissertation","_id":"14306"},{"citation":{"ama":"Locatello F, Vincent D, Tolstikhin I, Rätsch G, Gelly S, Schölkopf B. Competitive training of mixtures of independent deep generative models. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.1804.11130\">10.48550/arXiv.1804.11130</a>","ista":"Locatello F, Vincent D, Tolstikhin I, Rätsch G, Gelly S, Schölkopf B. Competitive training of mixtures of independent deep generative models. arXiv, 1804.11130.","ieee":"F. Locatello, D. Vincent, I. Tolstikhin, G. Rätsch, S. Gelly, and B. Schölkopf, “Competitive training of mixtures of independent deep generative models,” <i>arXiv</i>. .","short":"F. Locatello, D. Vincent, I. Tolstikhin, G. Rätsch, S. Gelly, B. Schölkopf, ArXiv (n.d.).","mla":"Locatello, Francesco, et al. “Competitive Training of Mixtures of Independent Deep Generative Models.” <i>ArXiv</i>, 1804.11130, doi:<a href=\"https://doi.org/10.48550/arXiv.1804.11130\">10.48550/arXiv.1804.11130</a>.","chicago":"Locatello, Francesco, Damien Vincent, Ilya Tolstikhin, Gunnar Rätsch, Sylvain Gelly, and Bernhard Schölkopf. “Competitive Training of Mixtures of Independent Deep Generative Models.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.1804.11130\">https://doi.org/10.48550/arXiv.1804.11130</a>.","apa":"Locatello, F., Vincent, D., Tolstikhin, I., Rätsch, G., Gelly, S., &#38; Schölkopf, B. (n.d.). Competitive training of mixtures of independent deep generative models. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.1804.11130\">https://doi.org/10.48550/arXiv.1804.11130</a>"},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.1804.11130"}],"article_number":"1804.11130","date_created":"2023-09-13T12:20:49Z","year":"2018","day":"30","status":"public","publication":"arXiv","doi":"10.48550/arXiv.1804.11130","external_id":{"arxiv":["1804.11130"]},"publication_status":"submitted","oa":1,"abstract":[{"lang":"eng","text":"A common assumption in causal modeling posits that the data is generated by a\r\nset of independent mechanisms, and algorithms should aim to recover this\r\nstructure. Standard unsupervised learning, however, is often concerned with\r\ntraining a single model to capture the overall distribution or aspects thereof.\r\nInspired by clustering approaches, we consider mixtures of implicit generative\r\nmodels that ``disentangle'' the independent generative mechanisms underlying\r\nthe data. Relying on an additional set of discriminators, we propose a\r\ncompetitive training procedure in which the models only need to capture the\r\nportion of the data distribution from which they can produce realistic samples.\r\nAs a by-product, each model is simpler and faster to train. We empirically show\r\nthat our approach splits the training distribution in a sensible way and\r\nincreases the quality of the generated samples."}],"article_processing_charge":"No","date_updated":"2024-10-14T12:31:09Z","department":[{"_id":"FrLo"}],"arxiv":1,"date_published":"2018-04-30T00:00:00Z","month":"04","language":[{"iso":"eng"}],"title":"Competitive training of mixtures of independent deep generative models","type":"preprint","author":[{"full_name":"Locatello, Francesco","orcid":"0000-0002-4850-0683","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","first_name":"Francesco","last_name":"Locatello"},{"full_name":"Vincent, Damien","last_name":"Vincent","first_name":"Damien"},{"full_name":"Tolstikhin, Ilya","last_name":"Tolstikhin","first_name":"Ilya"},{"first_name":"Gunnar","last_name":"Rätsch","full_name":"Rätsch, Gunnar"},{"full_name":"Gelly, Sylvain","first_name":"Sylvain","last_name":"Gelly"},{"last_name":"Schölkopf","first_name":"Bernhard","full_name":"Schölkopf, Bernhard"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","extern":"1","_id":"14327"},{"citation":{"mla":"Truckenbrodt, Sven M., et al. “Newly Produced Synaptic Vesicle Proteins Are Preferentially Used in Synaptic Transmission.” <i>The EMBO Journal</i>, vol. 37, no. 15, e98044, Wiley, 2018, doi:<a href=\"https://doi.org/10.15252/embj.201798044\">10.15252/embj.201798044</a>.","chicago":"Truckenbrodt, Sven M, Abhiyan Viplav, Sebsatian Jähne, Angela Vogts, Annette Denker, Hanna Wildhagen, Eugenio Fornasiero, and Silvio Rizzoli. “Newly Produced Synaptic Vesicle Proteins Are Preferentially Used in Synaptic Transmission.” <i>The EMBO Journal</i>. Wiley, 2018. <a href=\"https://doi.org/10.15252/embj.201798044\">https://doi.org/10.15252/embj.201798044</a>.","apa":"Truckenbrodt, S. M., Viplav, A., Jähne, S., Vogts, A., Denker, A., Wildhagen, H., … Rizzoli, S. (2018). Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. <i>The EMBO Journal</i>. Wiley. <a href=\"https://doi.org/10.15252/embj.201798044\">https://doi.org/10.15252/embj.201798044</a>","ama":"Truckenbrodt SM, Viplav A, Jähne S, et al. Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. <i>The EMBO Journal</i>. 2018;37(15). doi:<a href=\"https://doi.org/10.15252/embj.201798044\">10.15252/embj.201798044</a>","ista":"Truckenbrodt SM, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, Fornasiero E, Rizzoli S. 2018. Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. The EMBO Journal. 37(15), e98044.","ieee":"S. M. Truckenbrodt <i>et al.</i>, “Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission,” <i>The EMBO Journal</i>, vol. 37, no. 15. Wiley, 2018.","short":"S.M. Truckenbrodt, A. Viplav, S. Jähne, A. Vogts, A. Denker, H. Wildhagen, E. Fornasiero, S. Rizzoli, The EMBO Journal 37 (2018)."},"day":"01","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"month":"08","language":[{"iso":"eng"}],"date_published":"2018-08-01T00:00:00Z","department":[{"_id":"JoDa"}],"publisher":"Wiley","date_updated":"2024-10-09T20:58:32Z","isi":1,"oa":1,"file_date_updated":"2020-07-14T12:44:56Z","publist_id":"7778","_id":"145","scopus_import":"1","article_type":"original","oa_version":"Published Version","intvolume":"        37","acknowledgement":"We thank Reinhard Jahn for providing a plasmid for YFP-SNAP25. We thank Erwin Neher for help with the development of the mathematical model of the synaptic vesicle life cycle. We thank Martin Meschkat, Andreas Höbartner, Annedore Punge, and Peer Hoopmann for help with the experiments. We thank Burkhard Rammner for providing the illustrations of synaptic vesicle and protein dynamics. We thank Manuel Maidorn, Martin Helm, and Katharina N. Richter for critically reading the manuscript. S.T. was supported by an Excellence Stipend of the Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB). E.F.F. is a recipient of long-term fellowships from the European Molecular Biology Organization (ALTF_797-2012) and from the Human Frontier Science Program (HFSP_LT000830/2013). The work was supported by grants to S.O.R. from the European Research Council (ERC-2013-CoG NeuroMolAnatomy) and from the Deutsche Forschungsgemeinschaft (Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain, SFB1190/P09, SFB889/A05, and SFB1286/A03, and DFG RI 1967 7/1). The nanoSIMS instrument was funded by the German Federal Ministry of Education and Research (03F0626A).","type":"journal_article","has_accepted_license":"1","ddc":["570"],"corr_author":"1","file":[{"checksum":"a540feb6c9af6aefc78de531461a8835","relation":"main_file","access_level":"open_access","date_updated":"2020-07-14T12:44:56Z","file_size":2846470,"file_id":"5710","creator":"dernst","date_created":"2018-12-17T14:17:29Z","content_type":"application/pdf","file_name":"2018_EMBO_Truckenbrodt.pdf"}],"quality_controlled":"1","issue":"15","doi":"10.15252/embj.201798044","publication_identifier":{"issn":["0261-4189"]},"publication":"The EMBO Journal","year":"2018","date_created":"2018-12-11T11:44:52Z","article_number":"e98044","title":"Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission","article_processing_charge":"No","abstract":[{"text":"Aged proteins can become hazardous to cellular function, by accumulating molecular damage. This implies that cells should preferentially rely on newly produced ones. We tested this hypothesis in cultured hippocampal neurons, focusing on synaptic transmission. We found that newly synthesized vesicle proteins were incorporated in the actively recycling pool of vesicles responsible for all neurotransmitter release during physiological activity. We observed this for the calcium sensor Synaptotagmin 1, for the neurotransmitter transporter VGAT, and for the fusion protein VAMP2 (Synaptobrevin 2). Metabolic labeling of proteins and visualization by secondary ion mass spectrometry enabled us to query the entire protein makeup of the actively recycling vesicles, which we found to be younger than that of non-recycling vesicles. The young vesicle proteins remained in use for up to ~ 24 h, during which they participated in recycling a few hundred times. They were afterward reluctant to release and were degraded after an additional ~ 24–48 h. We suggest that the recycling pool of synaptic vesicles relies on newly synthesized proteins, while the inactive reserve pool contains older proteins.","lang":"eng"}],"publication_status":"published","external_id":{"pmid":["29950309"],"isi":["000440416900005"]},"pmid":1,"author":[{"last_name":"Truckenbrodt","first_name":"Sven M","id":"45812BD4-F248-11E8-B48F-1D18A9856A87","full_name":"Truckenbrodt, Sven M"},{"full_name":"Viplav, Abhiyan","first_name":"Abhiyan","last_name":"Viplav"},{"full_name":"Jähne, Sebsatian","first_name":"Sebsatian","last_name":"Jähne"},{"last_name":"Vogts","first_name":"Angela","full_name":"Vogts, Angela"},{"first_name":"Annette","last_name":"Denker","full_name":"Denker, Annette"},{"full_name":"Wildhagen, Hanna","last_name":"Wildhagen","first_name":"Hanna"},{"full_name":"Fornasiero, Eugenio","last_name":"Fornasiero","first_name":"Eugenio"},{"last_name":"Rizzoli","first_name":"Silvio","full_name":"Rizzoli, Silvio"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","volume":37},{"scopus_import":"1","_id":"146","publist_id":"7777","type":"journal_article","intvolume":"         4","oa_version":"Submitted Version","article_type":"original","date_updated":"2023-09-19T10:08:45Z","publisher":"Nature Publishing Group","department":[{"_id":"JiFr"}],"date_published":"2018-07-30T00:00:00Z","month":"07","language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:44:56Z","oa":1,"isi":1,"day":"30","status":"public","citation":{"chicago":"Shi, Chun Lin, Daniel von Wangenheim, Ullrich Herrmann, Mari Wildhagen, Ivan Kulik, Andreas Kopf, Takashi Ishida, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” <i>Nature Plants</i>. Nature Publishing Group, 2018. <a href=\"https://doi.org/10.1038/s41477-018-0212-z\">https://doi.org/10.1038/s41477-018-0212-z</a>.","apa":"Shi, C. L., von Wangenheim, D., Herrmann, U., Wildhagen, M., Kulik, I., Kopf, A., … Aalen, R. B. (2018). The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. <i>Nature Plants</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41477-018-0212-z\">https://doi.org/10.1038/s41477-018-0212-z</a>","mla":"Shi, Chun Lin, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” <i>Nature Plants</i>, vol. 4, no. 8, Nature Publishing Group, 2018, pp. 596–604, doi:<a href=\"https://doi.org/10.1038/s41477-018-0212-z\">10.1038/s41477-018-0212-z</a>.","short":"C.L. Shi, D. von Wangenheim, U. Herrmann, M. Wildhagen, I. Kulik, A. Kopf, T. Ishida, V. Olsson, M.K. Anker, M. Albert, M.A. Butenko, G. Felix, S. Sawa, M. Claassen, J. Friml, R.B. Aalen, Nature Plants 4 (2018) 596–604.","ieee":"C. L. Shi <i>et al.</i>, “The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling,” <i>Nature Plants</i>, vol. 4, no. 8. Nature Publishing Group, pp. 596–604, 2018.","ama":"Shi CL, von Wangenheim D, Herrmann U, et al. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. <i>Nature Plants</i>. 2018;4(8):596-604. doi:<a href=\"https://doi.org/10.1038/s41477-018-0212-z\">10.1038/s41477-018-0212-z</a>","ista":"Shi CL, von Wangenheim D, Herrmann U, Wildhagen M, Kulik I, Kopf A, Ishida T, Olsson V, Anker MK, Albert M, Butenko MA, Felix G, Sawa S, Claassen M, Friml J, Aalen RB. 2018. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. 4(8), 596–604."},"pmid":1,"related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/new-process-in-root-development-discovered/","description":"News on IST Homepage"}]},"volume":4,"author":[{"first_name":"Chun Lin","last_name":"Shi","full_name":"Shi, Chun Lin"},{"id":"49E91952-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6862-1247","full_name":"Von Wangenheim, Daniel","first_name":"Daniel","last_name":"Von Wangenheim"},{"full_name":"Herrmann, Ullrich","last_name":"Herrmann","first_name":"Ullrich"},{"full_name":"Wildhagen, Mari","last_name":"Wildhagen","first_name":"Mari"},{"last_name":"Kulik","first_name":"Ivan","id":"F0AB3FCE-02D1-11E9-BD0E-99399A5D3DEB","full_name":"Kulik, Ivan"},{"first_name":"Andreas","last_name":"Kopf","full_name":"Kopf, Andreas"},{"first_name":"Takashi","last_name":"Ishida","full_name":"Ishida, Takashi"},{"first_name":"Vilde","last_name":"Olsson","full_name":"Olsson, Vilde"},{"full_name":"Anker, Mari Kristine","last_name":"Anker","first_name":"Mari Kristine"},{"last_name":"Albert","first_name":"Markus","full_name":"Albert, Markus"},{"first_name":"Melinka A","last_name":"Butenko","full_name":"Butenko, Melinka A"},{"first_name":"Georg","last_name":"Felix","full_name":"Felix, Georg"},{"last_name":"Sawa","first_name":"Shinichiro","full_name":"Sawa, Shinichiro"},{"full_name":"Claassen, Manfred","last_name":"Claassen","first_name":"Manfred"},{"last_name":"Friml","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí"},{"full_name":"Aalen, Reidunn B","first_name":"Reidunn B","last_name":"Aalen"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","title":"The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling","publication_status":"published","external_id":{"pmid":["30061750"],"isi":["000443861300016"]},"abstract":[{"lang":"eng","text":"The root cap protects the stem cell niche of angiosperm roots from damage. In Arabidopsis, lateral root cap (LRC) cells covering the meristematic zone are regularly lost through programmed cell death, while the outermost layer of the root cap covering the tip is repeatedly sloughed. Efficient coordination with stem cells producing new layers is needed to maintain a constant size of the cap. We present a signalling pair, the peptide IDA-LIKE1 (IDL1) and its receptor HAESA-LIKE2 (HSL2), mediating such communication. Live imaging over several days characterized this process from initial fractures in LRC cell files to full separation of a layer. Enhanced expression of IDL1 in the separating root cap layers resulted in increased frequency of sloughing, balanced with generation of new layers in a HSL2-dependent manner. Transcriptome analyses linked IDL1-HSL2 signalling to the transcription factors BEARSKIN1/2 and genes associated with programmed cell death. Mutations in either IDL1 or HSL2 slowed down cell division, maturation and separation. Thus, IDL1-HSL2 signalling potentiates dynamic regulation of the homeostatic balance between stem cell division and sloughing activity."}],"article_processing_charge":"No","page":"596 - 604","publication":"Nature Plants","doi":"10.1038/s41477-018-0212-z","issue":"8","date_created":"2018-12-11T11:44:52Z","year":"2018","ddc":["580"],"has_accepted_license":"1","quality_controlled":"1","file":[{"file_id":"7043","access_level":"open_access","checksum":"da33101c76ee1b2dc5ab28fd2ccba9d0","relation":"main_file","date_updated":"2020-07-14T12:44:56Z","file_size":226829,"date_created":"2019-11-18T16:24:07Z","file_name":"2018_NaturePlants_Shi.pdf","content_type":"application/pdf","creator":"dernst"}]},{"publication":"The Plant Cell","doi":"10.1105/tpc.18.00127","publication_identifier":{"issn":["1040-4651"]},"issue":"10","date_created":"2018-12-11T11:44:52Z","year":"2018","ddc":["580"],"main_file_link":[{"url":"https://doi.org/10.1105/tpc.18.00127","open_access":"1"}],"quality_controlled":"1","corr_author":"1","pmid":1,"volume":30,"author":[{"last_name":"Kania","first_name":"Urszula","full_name":"Kania, Urszula","id":"4AE5C486-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Nodzyński, Tomasz","first_name":"Tomasz","last_name":"Nodzyński"},{"full_name":"Lu, Qing","first_name":"Qing","last_name":"Lu"},{"full_name":"Hicks, Glenn R","last_name":"Hicks","first_name":"Glenn R"},{"last_name":"Nerinckx","first_name":"Wim","full_name":"Nerinckx, Wim"},{"full_name":"Mishev, Kiril","last_name":"Mishev","first_name":"Kiril"},{"last_name":"Peurois","first_name":"Francois","full_name":"Peurois, Francois"},{"full_name":"Cherfils, Jacqueline","first_name":"Jacqueline","last_name":"Cherfils"},{"first_name":"Rycke Riet Maria","last_name":"De","full_name":"De, Rycke Riet Maria"},{"first_name":"Peter","last_name":"Grones","full_name":"Grones, Peter","id":"399876EC-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Robert","first_name":"Stéphanie","full_name":"Robert, Stéphanie"},{"full_name":"Russinova, Eugenia","last_name":"Russinova","first_name":"Eugenia"},{"last_name":"Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jirí"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes","external_id":{"isi":["000450000500023"],"pmid":["30018156"]},"publication_status":"published","abstract":[{"text":"The trafficking of subcellular cargos in eukaryotic cells crucially depends on vesicle budding, a process mediated by ARF-GEFs (ADP-ribosylation factor guanine nucleotide exchange factors). In plants, ARF-GEFs play essential roles in endocytosis, vacuolar trafficking, recycling, secretion, and polar trafficking. Moreover, they are important for plant development, mainly through controlling the polar subcellular localization of PIN-FORMED (PIN) transporters of the plant hormone auxin. Here, using a chemical genetics screen in Arabidopsis thaliana, we identified Endosidin 4 (ES4), an inhibitor of eukaryotic ARF-GEFs. ES4 acts similarly to and synergistically with the established ARF-GEF inhibitor Brefeldin A and has broad effects on intracellular trafficking, including endocytosis, exocytosis, and vacuolar targeting. Additionally, Arabidopsis and yeast (Sacharomyces cerevisiae) mutants defective in ARF-GEF show altered sensitivity to ES4. ES4 interferes with the activation-based membrane association of the ARF1 GTPases, but not of their mutant variants that are activated independently of ARF-GEF activity. Biochemical approaches and docking simulations confirmed that ES4 specifically targets the SEC7 domain-containing ARF-GEFs. These observations collectively identify ES4 as a chemical tool enabling the study of ARF-GEF-mediated processes, including ARF-GEF-mediated plant development.","lang":"eng"}],"article_processing_charge":"No","page":"2553 - 2572","status":"public","day":"12","ec_funded":1,"project":[{"_id":"25716A02-B435-11E9-9278-68D0E5697425","grant_number":"282300","call_identifier":"FP7","name":"Polarity and subcellular dynamics in plants"},{"_id":"261099A6-B435-11E9-9278-68D0E5697425","grant_number":"742985","call_identifier":"H2020","name":"Tracing Evolution of Auxin Transport and Polarity in Plants"}],"citation":{"ista":"Kania U, Nodzyński T, Lu Q, Hicks GR, Nerinckx W, Mishev K, Peurois F, Cherfils J, De RRM, Grones P, Robert S, Russinova E, Friml J. 2018. The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. The Plant Cell. 30(10), 2553–2572.","ama":"Kania U, Nodzyński T, Lu Q, et al. The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. <i>The Plant Cell</i>. 2018;30(10):2553-2572. doi:<a href=\"https://doi.org/10.1105/tpc.18.00127\">10.1105/tpc.18.00127</a>","ieee":"U. Kania <i>et al.</i>, “The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes,” <i>The Plant Cell</i>, vol. 30, no. 10. Oxford University Press, pp. 2553–2572, 2018.","short":"U. Kania, T. Nodzyński, Q. Lu, G.R. Hicks, W. Nerinckx, K. Mishev, F. Peurois, J. Cherfils, R.R.M. De, P. Grones, S. Robert, E. Russinova, J. Friml, The Plant Cell 30 (2018) 2553–2572.","mla":"Kania, Urszula, et al. “The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking in Eukaryotes.” <i>The Plant Cell</i>, vol. 30, no. 10, Oxford University Press, 2018, pp. 2553–72, doi:<a href=\"https://doi.org/10.1105/tpc.18.00127\">10.1105/tpc.18.00127</a>.","apa":"Kania, U., Nodzyński, T., Lu, Q., Hicks, G. R., Nerinckx, W., Mishev, K., … Friml, J. (2018). The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes. <i>The Plant Cell</i>. Oxford University Press. <a href=\"https://doi.org/10.1105/tpc.18.00127\">https://doi.org/10.1105/tpc.18.00127</a>","chicago":"Kania, Urszula, Tomasz Nodzyński, Qing Lu, Glenn R Hicks, Wim Nerinckx, Kiril Mishev, Francois Peurois, et al. “The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking in Eukaryotes.” <i>The Plant Cell</i>. Oxford University Press, 2018. <a href=\"https://doi.org/10.1105/tpc.18.00127\">https://doi.org/10.1105/tpc.18.00127</a>."},"scopus_import":"1","_id":"147","publist_id":"7776","type":"journal_article","acknowledgement":"We thank Gerd Jürgens, Sandra Richter, and Sheng Yang He for providing antibodies; Maciek Adamowski, Fernando Aniento, Sebastian Bednarek, Nico Callewaert, Matyás Fendrych, Elena Feraru, and Mugurel I. Feraru for helpful suggestions; Siamsa Doyle for critical reading of the manuscript and helpful comments and suggestions; and Stephanie Smith and Martine De Cock for help in editing and language corrections. We acknowledge the core facility Cellular Imaging of CEITEC supported by the Czech-BioImaging large RI project (LM2015062 funded by MEYS CR) for their support with obtaining scientific data presented in this article. Plant Sciences Core Facility of CEITEC Masaryk University is gratefully acknowledged for obtaining part of the scientific data presented in this article. We acknowledge support from the Fondation pour la Recherche Médicale and from the Institut National du Cancer (J.C.). The research leading to these results was funded by the European Research Council under the European Union's 7th Framework Program (FP7/2007-2013)/ERC grant agreement numbers 282300 and 742985 and the Czech Science Foundation GAČR (GA18-26981S; J.F.); Ministry of Education, Youth, and Sports/MEYS of the Czech Republic under the Project CEITEC 2020 (LQ1601; T.N.); the China Science Council for a predoctoral fellowship (Q.L.); a joint research project within the framework of cooperation between the Research Foundation-Flanders and the Bulgarian Academy of Sciences (VS.025.13N; K.M. and E.R.); Vetenskapsrådet and Vinnova (Verket för Innovationssystem; S.R.), Knut och Alice Wallenbergs Stiftelse via “Shapesystem” Grant 2012.0050 (S.R.), Kempe stiftelserna (P.G.), Tryggers CTS410 (P.G.).","intvolume":"        30","oa_version":"Published Version","article_type":"original","date_updated":"2026-06-18T17:36:26Z","publisher":"Oxford University Press","department":[{"_id":"JiFr"}],"date_published":"2018-11-12T00:00:00Z","language":[{"iso":"eng"}],"month":"11","oa":1,"isi":1},{"title":"The Chara genome: Secondary complexity and implications for plant terrestrialization","article_processing_charge":"No","page":"448 - 464.e24","publication_status":"published","external_id":{"isi":["000438482800019"],"pmid":["30007417"]},"abstract":[{"text":"Land plants evolved from charophytic algae, among which Charophyceae possess the most complex body plans. We present the genome of Chara braunii; comparison of the genome to those of land plants identified evolutionary novelties for plant terrestrialization and land plant heritage genes. C. braunii employs unique xylan synthases for cell wall biosynthesis, a phragmoplast (cell separation) mechanism similar to that of land plants, and many phytohormones. C. braunii plastids are controlled via land-plant-like retrograde signaling, and transcriptional regulation is more elaborate than in other algae. The morphological complexity of this organism may result from expanded gene families, with three cases of particular note: genes effecting tolerance to reactive oxygen species (ROS), LysM receptor-like kinases, and transcription factors (TFs). Transcriptomic analysis of sexual reproductive structures reveals intricate control by TFs, activity of the ROS gene network, and the ancestral use of plant-like storage and stress protection proteins in the zygote.","lang":"eng"}],"pmid":1,"author":[{"first_name":"Tomoaki","last_name":"Nishiyama","full_name":"Nishiyama, Tomoaki"},{"last_name":"Sakayama","first_name":"Hidetoshi","full_name":"Sakayama, Hidetoshi"},{"last_name":"De Vries","first_name":"Jan","full_name":"De Vries, Jan"},{"full_name":"Buschmann, Henrik","last_name":"Buschmann","first_name":"Henrik"},{"full_name":"Saint Marcoux, Denis","first_name":"Denis","last_name":"Saint Marcoux"},{"first_name":"Kristian","last_name":"Ullrich","full_name":"Ullrich, Kristian"},{"last_name":"Haas","first_name":"Fabian","full_name":"Haas, Fabian"},{"first_name":"Lisa","last_name":"Vanderstraeten","full_name":"Vanderstraeten, Lisa"},{"full_name":"Becker, Dirk","last_name":"Becker","first_name":"Dirk"},{"first_name":"Daniel","last_name":"Lang","full_name":"Lang, Daniel"},{"full_name":"Vosolsobě, Stanislav","last_name":"Vosolsobě","first_name":"Stanislav"},{"full_name":"Rombauts, Stephane","first_name":"Stephane","last_name":"Rombauts"},{"first_name":"Per","last_name":"Wilhelmsson","full_name":"Wilhelmsson, Per"},{"full_name":"Janitza, Philipp","first_name":"Philipp","last_name":"Janitza"},{"full_name":"Kern, Ramona","last_name":"Kern","first_name":"Ramona"},{"first_name":"Alexander","last_name":"Heyl","full_name":"Heyl, Alexander"},{"last_name":"Rümpler","first_name":"Florian","full_name":"Rümpler, Florian"},{"first_name":"Luz","last_name":"Calderón Villalobos","full_name":"Calderón Villalobos, Luz"},{"last_name":"Clay","first_name":"John","full_name":"Clay, John"},{"last_name":"Skokan","first_name":"Roman","full_name":"Skokan, Roman"},{"first_name":"Atsushi","last_name":"Toyoda","full_name":"Toyoda, Atsushi"},{"last_name":"Suzuki","first_name":"Yutaka","full_name":"Suzuki, Yutaka"},{"last_name":"Kagoshima","first_name":"Hiroshi","full_name":"Kagoshima, Hiroshi"},{"full_name":"Schijlen, Elio","first_name":"Elio","last_name":"Schijlen"},{"full_name":"Tajeshwar, Navindra","last_name":"Tajeshwar","first_name":"Navindra"},{"last_name":"Catarino","first_name":"Bruno","full_name":"Catarino, Bruno"},{"full_name":"Hetherington, Alexander","last_name":"Hetherington","first_name":"Alexander"},{"full_name":"Saltykova, Assia","last_name":"Saltykova","first_name":"Assia"},{"full_name":"Bonnot, Clemence","first_name":"Clemence","last_name":"Bonnot"},{"last_name":"Breuninger","first_name":"Holger","full_name":"Breuninger, Holger"},{"full_name":"Symeonidi, Aikaterini","last_name":"Symeonidi","first_name":"Aikaterini"},{"first_name":"Guru","last_name":"Radhakrishnan","full_name":"Radhakrishnan, Guru"},{"first_name":"Filip","last_name":"Van Nieuwerburgh","full_name":"Van Nieuwerburgh, Filip"},{"last_name":"Deforce","first_name":"Dieter","full_name":"Deforce, Dieter"},{"first_name":"Caren","last_name":"Chang","full_name":"Chang, Caren"},{"last_name":"Karol","first_name":"Kenneth","full_name":"Karol, Kenneth"},{"first_name":"Rainer","last_name":"Hedrich","full_name":"Hedrich, Rainer"},{"first_name":"Peter","last_name":"Ulvskov","full_name":"Ulvskov, Peter"},{"full_name":"Glöckner, Gernot","last_name":"Glöckner","first_name":"Gernot"},{"full_name":"Delwiche, Charles","first_name":"Charles","last_name":"Delwiche"},{"full_name":"Petrášek, Jan","first_name":"Jan","last_name":"Petrášek"},{"first_name":"Yves","last_name":"Van De Peer","full_name":"Van De Peer, Yves"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","first_name":"Jirí","last_name":"Friml"},{"first_name":"Mary","last_name":"Beilby","full_name":"Beilby, Mary"},{"full_name":"Dolan, Liam","last_name":"Dolan","first_name":"Liam"},{"full_name":"Kohara, Yuji","first_name":"Yuji","last_name":"Kohara"},{"last_name":"Sugano","first_name":"Sumio","full_name":"Sugano, Sumio"},{"full_name":"Fujiyama, Asao","last_name":"Fujiyama","first_name":"Asao"},{"full_name":"Delaux, Pierre Marc","first_name":"Pierre Marc","last_name":"Delaux"},{"last_name":"Quint","first_name":"Marcel","full_name":"Quint, Marcel"},{"full_name":"Theissen, Gunter","last_name":"Theissen","first_name":"Gunter"},{"full_name":"Hagemann, Martin","first_name":"Martin","last_name":"Hagemann"},{"full_name":"Harholt, Jesper","last_name":"Harholt","first_name":"Jesper"},{"full_name":"Dunand, Christophe","last_name":"Dunand","first_name":"Christophe"},{"full_name":"Zachgo, Sabine","first_name":"Sabine","last_name":"Zachgo"},{"full_name":"Langdale, Jane","first_name":"Jane","last_name":"Langdale"},{"full_name":"Maumus, Florian","first_name":"Florian","last_name":"Maumus"},{"first_name":"Dominique","last_name":"Van Der Straeten","full_name":"Van Der Straeten, Dominique"},{"last_name":"Gould","first_name":"Sven B","full_name":"Gould, Sven B"},{"last_name":"Rensing","first_name":"Stefan","full_name":"Rensing, Stefan"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":174,"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pubmed/30007417"}],"ddc":["580"],"quality_controlled":"1","doi":"10.1016/j.cell.2018.06.033","issue":"2","publication":"Cell","date_created":"2018-12-11T11:44:53Z","year":"2018","date_published":"2018-07-12T00:00:00Z","month":"07","language":[{"iso":"eng"}],"date_updated":"2026-06-18T17:39:09Z","publisher":"Cell Press","department":[{"_id":"JiFr"}],"isi":1,"oa":1,"publist_id":"7774","scopus_import":"1","_id":"148","oa_version":"Published Version","intvolume":"       174","type":"journal_article","acknowledgement":"In-Data-Review","citation":{"mla":"Nishiyama, Tomoaki, et al. “The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization.” <i>Cell</i>, vol. 174, no. 2, Cell Press, 2018, p. 448–464.e24, doi:<a href=\"https://doi.org/10.1016/j.cell.2018.06.033\">10.1016/j.cell.2018.06.033</a>.","apa":"Nishiyama, T., Sakayama, H., De Vries, J., Buschmann, H., Saint Marcoux, D., Ullrich, K., … Rensing, S. (2018). The Chara genome: Secondary complexity and implications for plant terrestrialization. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2018.06.033\">https://doi.org/10.1016/j.cell.2018.06.033</a>","chicago":"Nishiyama, Tomoaki, Hidetoshi Sakayama, Jan De Vries, Henrik Buschmann, Denis Saint Marcoux, Kristian Ullrich, Fabian Haas, et al. “The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization.” <i>Cell</i>. Cell Press, 2018. <a href=\"https://doi.org/10.1016/j.cell.2018.06.033\">https://doi.org/10.1016/j.cell.2018.06.033</a>.","ama":"Nishiyama T, Sakayama H, De Vries J, et al. The Chara genome: Secondary complexity and implications for plant terrestrialization. <i>Cell</i>. 2018;174(2):448-464.e24. doi:<a href=\"https://doi.org/10.1016/j.cell.2018.06.033\">10.1016/j.cell.2018.06.033</a>","ista":"Nishiyama T, Sakayama H, De Vries J, Buschmann H, Saint Marcoux D, Ullrich K, Haas F, Vanderstraeten L, Becker D, Lang D, Vosolsobě S, Rombauts S, Wilhelmsson P, Janitza P, Kern R, Heyl A, Rümpler F, Calderón Villalobos L, Clay J, Skokan R, Toyoda A, Suzuki Y, Kagoshima H, Schijlen E, Tajeshwar N, Catarino B, Hetherington A, Saltykova A, Bonnot C, Breuninger H, Symeonidi A, Radhakrishnan G, Van Nieuwerburgh F, Deforce D, Chang C, Karol K, Hedrich R, Ulvskov P, Glöckner G, Delwiche C, Petrášek J, Van De Peer Y, Friml J, Beilby M, Dolan L, Kohara Y, Sugano S, Fujiyama A, Delaux PM, Quint M, Theissen G, Hagemann M, Harholt J, Dunand C, Zachgo S, Langdale J, Maumus F, Van Der Straeten D, Gould SB, Rensing S. 2018. The Chara genome: Secondary complexity and implications for plant terrestrialization. Cell. 174(2), 448–464.e24.","short":"T. Nishiyama, H. Sakayama, J. De Vries, H. Buschmann, D. Saint Marcoux, K. Ullrich, F. Haas, L. Vanderstraeten, D. Becker, D. Lang, S. Vosolsobě, S. Rombauts, P. Wilhelmsson, P. Janitza, R. Kern, A. Heyl, F. Rümpler, L. Calderón Villalobos, J. Clay, R. Skokan, A. Toyoda, Y. Suzuki, H. Kagoshima, E. Schijlen, N. Tajeshwar, B. Catarino, A. Hetherington, A. Saltykova, C. Bonnot, H. Breuninger, A. Symeonidi, G. Radhakrishnan, F. Van Nieuwerburgh, D. Deforce, C. Chang, K. Karol, R. Hedrich, P. Ulvskov, G. Glöckner, C. Delwiche, J. Petrášek, Y. Van De Peer, J. Friml, M. Beilby, L. Dolan, Y. Kohara, S. Sugano, A. Fujiyama, P.M. Delaux, M. Quint, G. Theissen, M. Hagemann, J. Harholt, C. Dunand, S. Zachgo, J. Langdale, F. Maumus, D. Van Der Straeten, S.B. Gould, S. Rensing, Cell 174 (2018) 448–464.e24.","ieee":"T. Nishiyama <i>et al.</i>, “The Chara genome: Secondary complexity and implications for plant terrestrialization,” <i>Cell</i>, vol. 174, no. 2. Cell Press, p. 448–464.e24, 2018."},"project":[{"name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","grant_number":"742985","_id":"261099A6-B435-11E9-9278-68D0E5697425"}],"status":"public","day":"12","ec_funded":1},{"intvolume":"       560","oa_version":"Submitted Version","article_type":"original","type":"journal_article","scopus_import":"1","_id":"150","isi":1,"oa":1,"date_published":"2018-08-29T00:00:00Z","language":[{"iso":"eng"}],"month":"08","date_updated":"2023-09-12T07:44:37Z","department":[{"_id":"FlSc"}],"publisher":"Nature Publishing Group","status":"public","day":"29","citation":{"ama":"Dick R, Zadrozny KK, Xu C, et al. Inositol phosphates are assembly co-factors for HIV-1. <i>Nature</i>. 2018;560(7719):509–512. doi:<a href=\"https://doi.org/10.1038/s41586-018-0396-4\">10.1038/s41586-018-0396-4</a>","ista":"Dick R, Zadrozny KK, Xu C, Schur FK, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser PBK, Johnson MC, Pornillos O, Vogt V. 2018. Inositol phosphates are assembly co-factors for HIV-1. Nature. 560(7719), 509–512.","ieee":"R. Dick <i>et al.</i>, “Inositol phosphates are assembly co-factors for HIV-1,” <i>Nature</i>, vol. 560, no. 7719. Nature Publishing Group, pp. 509–512, 2018.","short":"R. Dick, K.K. Zadrozny, C. Xu, F.K. Schur, T.D. Lyddon, C.L. Ricana, J.M. Wagner, J.R. Perilla, P.B.K. Ganser, M.C. Johnson, O. Pornillos, V. Vogt, Nature 560 (2018) 509–512.","mla":"Dick, Robert, et al. “Inositol Phosphates Are Assembly Co-Factors for HIV-1.” <i>Nature</i>, vol. 560, no. 7719, Nature Publishing Group, 2018, pp. 509–512, doi:<a href=\"https://doi.org/10.1038/s41586-018-0396-4\">10.1038/s41586-018-0396-4</a>.","apa":"Dick, R., Zadrozny, K. K., Xu, C., Schur, F. K., Lyddon, T. D., Ricana, C. L., … Vogt, V. (2018). Inositol phosphates are assembly co-factors for HIV-1. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41586-018-0396-4\">https://doi.org/10.1038/s41586-018-0396-4</a>","chicago":"Dick, Robert, Kaneil K Zadrozny, Chaoyi Xu, Florian KM Schur, Terri D Lyddon, Clifton L Ricana, Jonathan M Wagner, et al. “Inositol Phosphates Are Assembly Co-Factors for HIV-1.” <i>Nature</i>. Nature Publishing Group, 2018. <a href=\"https://doi.org/10.1038/s41586-018-0396-4\">https://doi.org/10.1038/s41586-018-0396-4</a>."},"author":[{"first_name":"Robert","last_name":"Dick","full_name":"Dick, Robert"},{"first_name":"Kaneil K","last_name":"Zadrozny","full_name":"Zadrozny, Kaneil K"},{"last_name":"Xu","first_name":"Chaoyi","full_name":"Xu, Chaoyi"},{"first_name":"Florian","last_name":"Schur","full_name":"Schur, Florian","orcid":"0000-0003-4790-8078","id":"48AD8942-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Lyddon, Terri D","first_name":"Terri D","last_name":"Lyddon"},{"full_name":"Ricana, Clifton L","last_name":"Ricana","first_name":"Clifton L"},{"full_name":"Wagner, Jonathan M","first_name":"Jonathan M","last_name":"Wagner"},{"last_name":"Perilla","first_name":"Juan R","full_name":"Perilla, Juan R"},{"full_name":"Ganser, Pornillos Barbie K","first_name":"Pornillos Barbie K","last_name":"Ganser"},{"full_name":"Johnson, Marc C","first_name":"Marc C","last_name":"Johnson"},{"first_name":"Owen","last_name":"Pornillos","full_name":"Pornillos, Owen"},{"full_name":"Vogt, Volker","first_name":"Volker","last_name":"Vogt"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","volume":560,"pmid":1,"related_material":{"link":[{"url":"https://doi.org/10.1038/s41586-018-0505-4","relation":"erratum"}]},"article_processing_charge":"No","page":"509–512","external_id":{"pmid":["30158708"],"isi":["000442483400046"]},"publication_status":"published","abstract":[{"text":"A short, 14-amino-acid segment called SP1, located in the Gag structural protein1, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide and seven preceding residues fold into a six-helix bundle, which holds together the Gag hexamer and facilitates the formation of a curved immature hexagonal lattice underneath the viral membrane2,3. Upon completion of assembly and budding, proteolytic cleavage of Gag leads to virus maturation, in which the immature lattice is broken down; the liberated CA domain of Gag then re-assembles into the mature conical capsid that encloses the viral genome and associated enzymes. Folding and proteolysis of the six-helix bundle are crucial rate-limiting steps of both Gag assembly and disassembly, and the six-helix bundle is an established target of HIV-1 inhibitors4,5. Here, using a combination of structural and functional analyses, we show that inositol hexakisphosphate (InsP6, also known as IP6) facilitates the formation of the six-helix bundle and assembly of the immature HIV-1 Gag lattice. IP6 makes ionic contacts with two rings of lysine residues at the centre of the Gag hexamer. Proteolytic cleavage then unmasks an alternative binding site, where IP6 interaction promotes the assembly of the mature capsid lattice. These studies identify IP6 as a naturally occurring small molecule that promotes both assembly and maturation of HIV-1.","lang":"eng"}],"title":"Inositol phosphates are assembly co-factors for HIV-1","date_created":"2018-12-11T11:44:53Z","year":"2018","doi":"10.1038/s41586-018-0396-4","publication_identifier":{"eissn":["1476-4687"]},"issue":"7719","publication":"Nature","quality_controlled":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242333/","open_access":"1"}]},{"oa":1,"date_updated":"2024-04-09T11:07:07Z","publisher":"Oxford University Press","date_published":"2018-09-06T00:00:00Z","language":[{"iso":"eng"}],"month":"09","type":"journal_article","oa_version":"Published Version","intvolume":"        46","article_type":"original","scopus_import":"1","_id":"15143","citation":{"ama":"Bravo JPK, Borodavka A, Barth A, et al. Stability of local secondary structure determines selectivity of viral RNA chaperones. <i>Nucleic Acids Research</i>. 2018;46(15):7924-7937. doi:<a href=\"https://doi.org/10.1093/nar/gky394\">10.1093/nar/gky394</a>","ista":"Bravo JPK, Borodavka A, Barth A, Calabrese AN, Mojzes P, Cockburn JJB, Lamb DC, Tuma R. 2018. Stability of local secondary structure determines selectivity of viral RNA chaperones. Nucleic Acids Research. 46(15), 7924–7937.","short":"J.P.K. Bravo, A. Borodavka, A. Barth, A.N. Calabrese, P. Mojzes, J.J.B. Cockburn, D.C. Lamb, R. Tuma, Nucleic Acids Research 46 (2018) 7924–7937.","ieee":"J. P. K. Bravo <i>et al.</i>, “Stability of local secondary structure determines selectivity of viral RNA chaperones,” <i>Nucleic Acids Research</i>, vol. 46, no. 15. Oxford University Press, pp. 7924–7937, 2018.","mla":"Bravo, Jack Peter Kelly, et al. “Stability of Local Secondary Structure Determines Selectivity of Viral RNA Chaperones.” <i>Nucleic Acids Research</i>, vol. 46, no. 15, Oxford University Press, 2018, pp. 7924–37, doi:<a href=\"https://doi.org/10.1093/nar/gky394\">10.1093/nar/gky394</a>.","apa":"Bravo, J. P. K., Borodavka, A., Barth, A., Calabrese, A. N., Mojzes, P., Cockburn, J. J. B., … Tuma, R. (2018). Stability of local secondary structure determines selectivity of viral RNA chaperones. <i>Nucleic Acids Research</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/nar/gky394\">https://doi.org/10.1093/nar/gky394</a>","chicago":"Bravo, Jack Peter Kelly, Alexander Borodavka, Anders Barth, Antonio N Calabrese, Peter Mojzes, Joseph J B Cockburn, Don C Lamb, and Roman Tuma. “Stability of Local Secondary Structure Determines Selectivity of Viral RNA Chaperones.” <i>Nucleic Acids Research</i>. Oxford University Press, 2018. <a href=\"https://doi.org/10.1093/nar/gky394\">https://doi.org/10.1093/nar/gky394</a>."},"status":"public","day":"06","publication_status":"published","external_id":{"pmid":["29796667"]},"abstract":[{"text":"To maintain genome integrity, segmented double-stranded RNA viruses of the Reoviridae family must accurately select and package a complete set of up to a dozen distinct genomic RNAs. It is thought that the high fidelity segmented genome assembly involves multiple sequence-specific RNA–RNA interactions between single-stranded RNA segment precursors. These are mediated by virus-encoded non-structural proteins with RNA chaperone-like activities, such as rotavirus (RV) NSP2 and avian reovirus σNS. Here, we compared the abilities of NSP2 and σNS to mediate sequence-specific interactions between RV genomic segment precursors. Despite their similar activities, NSP2 successfully promotes inter-segment association, while σNS fails to do so. To understand the mechanisms underlying such selectivity in promoting inter-molecular duplex formation, we compared RNA-binding and helix-unwinding activities of both proteins. We demonstrate that octameric NSP2 binds structured RNAs with high affinity, resulting in efficient intramolecular RNA helix disruption. Hexameric σNS oligomerizes into an octamer that binds two RNAs, yet it exhibits only limited RNA-unwinding activity compared to NSP2. Thus, the formation of intersegment RNA–RNA interactions is governed by both helix-unwinding capacity of the chaperones and stability of RNA structure. We propose that this protein-mediated RNA selection mechanism may underpin the high fidelity assembly of multi-segmented RNA genomes in Reoviridae.","lang":"eng"}],"article_processing_charge":"Yes","page":"7924-7937","keyword":["Genetics"],"title":"Stability of local secondary structure determines selectivity of viral RNA chaperones","volume":46,"author":[{"last_name":"Bravo","first_name":"Jack Peter Kelly","full_name":"Bravo, Jack Peter Kelly","id":"96aecfa5-8931-11ee-af30-aa6a5d6eee0e","orcid":"0000-0003-0456-0753"},{"full_name":"Borodavka, Alexander","last_name":"Borodavka","first_name":"Alexander"},{"full_name":"Barth, Anders","first_name":"Anders","last_name":"Barth"},{"full_name":"Calabrese, Antonio N","first_name":"Antonio N","last_name":"Calabrese"},{"last_name":"Mojzes","first_name":"Peter","full_name":"Mojzes, Peter"},{"full_name":"Cockburn, Joseph J B","last_name":"Cockburn","first_name":"Joseph J B"},{"first_name":"Don C","last_name":"Lamb","full_name":"Lamb, Don C"},{"full_name":"Tuma, Roman","first_name":"Roman","last_name":"Tuma"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","pmid":1,"quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/nar/gky394"}],"date_created":"2024-03-20T10:43:13Z","year":"2018","publication":"Nucleic Acids Research","doi":"10.1093/nar/gky394","publication_identifier":{"issn":["0305-1048"],"eissn":["1362-4962"]},"issue":"15"},{"title":"Mammalian mitochondrial complex I structure and disease causing mutations","abstract":[{"text":"Complex I has an essential role in ATP production by coupling electron transfer from NADH to quinone with translocation of protons across the inner mitochondrial membrane. Isolated complex I deficiency is a frequent cause of mitochondrial inherited diseases. Complex I has also been implicated in cancer, ageing, and neurodegenerative conditions. Until recently, the understanding of complex I deficiency on the molecular level was limited due to the lack of high-resolution structures of the enzyme. However, due to developments in single particle cryo-electron microscopy (cryo-EM), recent studies have reported nearly atomic resolution maps and models of mitochondrial complex I. These structures significantly add to our understanding of complex I mechanism and assembly. The disease-causing mutations are discussed here in their structural context.","lang":"eng"}],"publication_status":"published","external_id":{"isi":["000445118200007"]},"page":"835 - 867","article_processing_charge":"No","volume":28,"author":[{"full_name":"Fiedorczuk, Karol","id":"5BFF67CE-02D1-11E9-B11A-A5A4D7DFFFD0","first_name":"Karol","last_name":"Fiedorczuk"},{"first_name":"Leonid A","last_name":"Sazanov","full_name":"Sazanov, Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0977-7989"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","ddc":["572"],"has_accepted_license":"1","file":[{"file_id":"6994","access_level":"open_access","relation":"main_file","checksum":"ef6d2b4e1fd63948539639242610bfa6","date_updated":"2020-07-14T12:45:00Z","file_size":2185385,"date_created":"2019-11-07T12:55:20Z","content_type":"application/pdf","file_name":"SasanovFinalMS+EdComments_LS_allacc_withFigs.pdf","creator":"lsazanov"}],"quality_controlled":"1","publication":"Trends in Cell Biology","issue":"10","doi":"10.1016/j.tcb.2018.06.006","year":"2018","date_created":"2018-12-11T11:44:54Z","department":[{"_id":"LeSa"}],"publisher":"Elsevier","date_updated":"2023-09-13T08:51:56Z","month":"07","language":[{"iso":"eng"}],"date_published":"2018-07-26T00:00:00Z","oa":1,"file_date_updated":"2020-07-14T12:45:00Z","isi":1,"_id":"152","scopus_import":"1","publist_id":"7769","type":"journal_article","article_type":"original","oa_version":"Submitted Version","intvolume":"        28","citation":{"mla":"Fiedorczuk, Karol, and Leonid A. Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” <i>Trends in Cell Biology</i>, vol. 28, no. 10, Elsevier, 2018, pp. 835–67, doi:<a href=\"https://doi.org/10.1016/j.tcb.2018.06.006\">10.1016/j.tcb.2018.06.006</a>.","apa":"Fiedorczuk, K., &#38; Sazanov, L. A. (2018). Mammalian mitochondrial complex I structure and disease causing mutations. <i>Trends in Cell Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tcb.2018.06.006\">https://doi.org/10.1016/j.tcb.2018.06.006</a>","chicago":"Fiedorczuk, Karol, and Leonid A Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” <i>Trends in Cell Biology</i>. Elsevier, 2018. <a href=\"https://doi.org/10.1016/j.tcb.2018.06.006\">https://doi.org/10.1016/j.tcb.2018.06.006</a>.","ama":"Fiedorczuk K, Sazanov LA. Mammalian mitochondrial complex I structure and disease causing mutations. <i>Trends in Cell Biology</i>. 2018;28(10):835-867. doi:<a href=\"https://doi.org/10.1016/j.tcb.2018.06.006\">10.1016/j.tcb.2018.06.006</a>","ista":"Fiedorczuk K, Sazanov LA. 2018. Mammalian mitochondrial complex I structure and disease causing mutations. Trends in Cell Biology. 28(10), 835–867.","short":"K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.","ieee":"K. Fiedorczuk and L. A. Sazanov, “Mammalian mitochondrial complex I structure and disease causing mutations,” <i>Trends in Cell Biology</i>, vol. 28, no. 10. Elsevier, pp. 835–867, 2018."},"day":"26","status":"public","tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"}},{"article_processing_charge":"No","abstract":[{"text":"In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry (eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced “spectral-timing-polarimetry” techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process. ","lang":"eng"}],"publication_status":"published","external_id":{"arxiv":["1812.04022"]},"title":"Accretion in strong field gravity with eXTP","keyword":["General Physics and Astronomy"],"extern":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"last_name":"Rosa","first_name":"Alessandra De","full_name":"Rosa, Alessandra De"},{"full_name":"Uttley, Phil","first_name":"Phil","last_name":"Uttley"},{"full_name":"Gou, LiJun","last_name":"Gou","first_name":"LiJun"},{"first_name":"Yuan","last_name":"Liu","full_name":"Liu, Yuan"},{"first_name":"Cosimo","last_name":"Bambi","full_name":"Bambi, Cosimo"},{"first_name":"Didier","last_name":"Barret","full_name":"Barret, Didier"},{"last_name":"Belloni","first_name":"Tomaso","full_name":"Belloni, Tomaso"},{"first_name":"Emanuele","last_name":"Berti","full_name":"Berti, Emanuele"},{"full_name":"Bianchi, Stefano","first_name":"Stefano","last_name":"Bianchi"},{"full_name":"Caiazzo, Ilaria","orcid":"0000-0002-4770-5388","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","last_name":"Caiazzo","first_name":"Ilaria"},{"full_name":"Casella, Piergiorgio","last_name":"Casella","first_name":"Piergiorgio"},{"full_name":"Feroci, Marco","last_name":"Feroci","first_name":"Marco"},{"full_name":"Ferrari, Valeria","last_name":"Ferrari","first_name":"Valeria"},{"full_name":"Gualtieri, Leonardo","first_name":"Leonardo","last_name":"Gualtieri"},{"first_name":"Jeremy","last_name":"Heyl","full_name":"Heyl, Jeremy"},{"first_name":"Adam","last_name":"Ingram","full_name":"Ingram, Adam"},{"full_name":"Karas, Vladimir","first_name":"Vladimir","last_name":"Karas"},{"full_name":"Lu, FangJun","first_name":"FangJun","last_name":"Lu"},{"full_name":"Luo, Bin","first_name":"Bin","last_name":"Luo"},{"full_name":"Matt, Giorgio","last_name":"Matt","first_name":"Giorgio"},{"full_name":"Motta, Sara","last_name":"Motta","first_name":"Sara"},{"full_name":"Neilsen, Joseph","last_name":"Neilsen","first_name":"Joseph"},{"full_name":"Pani, Paolo","last_name":"Pani","first_name":"Paolo"},{"full_name":"Santangelo, Andrea","first_name":"Andrea","last_name":"Santangelo"},{"full_name":"Shu, XinWen","last_name":"Shu","first_name":"XinWen"},{"full_name":"Wang, JunFeng","last_name":"Wang","first_name":"JunFeng"},{"last_name":"Wang","first_name":"Jian-Min","full_name":"Wang, Jian-Min"},{"full_name":"Xue, YongQuan","first_name":"YongQuan","last_name":"Xue"},{"last_name":"Xu","first_name":"YuPeng","full_name":"Xu, YuPeng"},{"first_name":"WeiMin","last_name":"Yuan","full_name":"Yuan, WeiMin"},{"first_name":"YeFei","last_name":"Yuan","full_name":"Yuan, YeFei"},{"first_name":"Shuang-Nan","last_name":"Zhang","full_name":"Zhang, Shuang-Nan"},{"last_name":"Zhang","first_name":"Shu","full_name":"Zhang, Shu"},{"first_name":"Ivan","last_name":"Agudo","full_name":"Agudo, Ivan"},{"full_name":"Amati, Lorenzo","first_name":"Lorenzo","last_name":"Amati"},{"last_name":"Andersson","first_name":"Nils","full_name":"Andersson, Nils"},{"last_name":"Baglio","first_name":"Cristina","full_name":"Baglio, Cristina"},{"last_name":"Bakala","first_name":"Pavel","full_name":"Bakala, Pavel"},{"last_name":"Baykal","first_name":"Altan","full_name":"Baykal, Altan"},{"full_name":"Bhattacharyya, Sudip","first_name":"Sudip","last_name":"Bhattacharyya"},{"full_name":"Bombaci, Ignazio","last_name":"Bombaci","first_name":"Ignazio"},{"first_name":"Niccoló","last_name":"Bucciantini","full_name":"Bucciantini, Niccoló"},{"first_name":"Fiamma","last_name":"Capitanio","full_name":"Capitanio, Fiamma"},{"first_name":"Riccardo","last_name":"Ciolfi","full_name":"Ciolfi, Riccardo"},{"last_name":"Cui","first_name":"Wei K.","full_name":"Cui, Wei K."},{"full_name":"D’Ammando, Filippo","last_name":"D’Ammando","first_name":"Filippo"},{"last_name":"Dauser","first_name":"Thomas","full_name":"Dauser, Thomas"},{"full_name":"Del Santo, Melania","last_name":"Del Santo","first_name":"Melania"},{"last_name":"De Marco","first_name":"Barbara","full_name":"De Marco, Barbara"},{"full_name":"Di Salvo, Tiziana","first_name":"Tiziana","last_name":"Di Salvo"},{"full_name":"Done, Chris","first_name":"Chris","last_name":"Done"},{"first_name":"Michal","last_name":"Dovčiak","full_name":"Dovčiak, Michal"},{"first_name":"Andrew C.","last_name":"Fabian","full_name":"Fabian, Andrew C."},{"full_name":"Falanga, Maurizio","last_name":"Falanga","first_name":"Maurizio"},{"last_name":"Gambino","first_name":"Angelo Francesco","full_name":"Gambino, Angelo Francesco"},{"full_name":"Gendre, Bruce","first_name":"Bruce","last_name":"Gendre"},{"last_name":"Grinberg","first_name":"Victoria","full_name":"Grinberg, Victoria"},{"full_name":"Heger, Alexander","first_name":"Alexander","last_name":"Heger"},{"first_name":"Jeroen","last_name":"Homan","full_name":"Homan, Jeroen"},{"last_name":"Iaria","first_name":"Rosario","full_name":"Iaria, Rosario"},{"full_name":"Jiang, JiaChen","first_name":"JiaChen","last_name":"Jiang"},{"full_name":"Jin, ChiChuan","last_name":"Jin","first_name":"ChiChuan"},{"full_name":"Koerding, Elmar","first_name":"Elmar","last_name":"Koerding"},{"full_name":"Linares, Manu","last_name":"Linares","first_name":"Manu"},{"full_name":"Liu, Zhu","last_name":"Liu","first_name":"Zhu"},{"last_name":"Maccarone","first_name":"Thomas J.","full_name":"Maccarone, Thomas J."},{"first_name":"Julien","last_name":"Malzac","full_name":"Malzac, Julien"},{"full_name":"Manousakis, Antonios","last_name":"Manousakis","first_name":"Antonios"},{"full_name":"Marin, Frédéric","last_name":"Marin","first_name":"Frédéric"},{"first_name":"Andrea","last_name":"Marinucci","full_name":"Marinucci, Andrea"},{"first_name":"Missagh","last_name":"Mehdipour","full_name":"Mehdipour, Missagh"},{"last_name":"Méndez","first_name":"Mariano","full_name":"Méndez, Mariano"},{"last_name":"Migliari","first_name":"Simone","full_name":"Migliari, Simone"},{"full_name":"Miller, Cole","first_name":"Cole","last_name":"Miller"},{"last_name":"Miniutti","first_name":"Giovanni","full_name":"Miniutti, Giovanni"},{"full_name":"Nardini, Emanuele","first_name":"Emanuele","last_name":"Nardini"},{"first_name":"Paul T.","last_name":"O’Brien","full_name":"O’Brien, Paul T."},{"full_name":"Osborne, Julian P.","last_name":"Osborne","first_name":"Julian P."},{"last_name":"Petrucci","first_name":"Pierre Olivier","full_name":"Petrucci, Pierre Olivier"},{"last_name":"Possenti","first_name":"Andrea","full_name":"Possenti, Andrea"},{"last_name":"Riggio","first_name":"Alessandro","full_name":"Riggio, Alessandro"},{"full_name":"Rodriguez, Jerome","first_name":"Jerome","last_name":"Rodriguez"},{"full_name":"Sanna, Andrea","first_name":"Andrea","last_name":"Sanna"},{"last_name":"Shao","first_name":"LiJing","full_name":"Shao, LiJing"},{"last_name":"Sobolewska","first_name":"Malgosia","full_name":"Sobolewska, Malgosia"},{"full_name":"Sramkova, Eva","last_name":"Sramkova","first_name":"Eva"},{"full_name":"Stevens, Abigail L.","first_name":"Abigail L.","last_name":"Stevens"},{"first_name":"Holger","last_name":"Stiele","full_name":"Stiele, Holger"},{"full_name":"Stratta, Giulia","last_name":"Stratta","first_name":"Giulia"},{"first_name":"Zdenek","last_name":"Stuchlik","full_name":"Stuchlik, Zdenek"},{"last_name":"Svoboda","first_name":"Jiri","full_name":"Svoboda, Jiri"},{"full_name":"Tamburini, Fabrizio","first_name":"Fabrizio","last_name":"Tamburini"},{"last_name":"Tauris","first_name":"Thomas M.","full_name":"Tauris, Thomas M."},{"first_name":"Francesco","last_name":"Tombesi","full_name":"Tombesi, Francesco"},{"full_name":"Torok, Gabriel","first_name":"Gabriel","last_name":"Torok"},{"first_name":"Martin","last_name":"Urbanec","full_name":"Urbanec, Martin"},{"full_name":"Vincent, Frederic","last_name":"Vincent","first_name":"Frederic"},{"full_name":"Wu, QingWen","first_name":"QingWen","last_name":"Wu"},{"full_name":"Yuan, Feng","last_name":"Yuan","first_name":"Feng"},{"first_name":"Jean J. M.","last_name":"in’ t Zand","full_name":"in’ t Zand, Jean J. M."},{"first_name":"Andrzej A.","last_name":"Zdziarski","full_name":"Zdziarski, Andrzej A."},{"last_name":"Zhou","first_name":"XinLin","full_name":"Zhou, XinLin"}],"volume":62,"quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.1812.04022"}],"year":"2018","date_created":"2024-03-26T10:37:41Z","article_number":"29504","issue":"2","publication_identifier":{"eissn":["1869-1927"],"issn":["1674-7348"]},"doi":"10.1007/s11433-018-9297-0","publication":"Science China Physics, Mechanics & Astronomy","oa":1,"month":"12","language":[{"iso":"eng"}],"date_published":"2018-12-07T00:00:00Z","publisher":"Springer Nature","arxiv":1,"date_updated":"2024-04-05T07:12:09Z","article_type":"original","intvolume":"        62","oa_version":"Preprint","type":"journal_article","_id":"15232","scopus_import":"1","citation":{"chicago":"Rosa, Alessandra De, Phil Uttley, LiJun Gou, Yuan Liu, Cosimo Bambi, Didier Barret, Tomaso Belloni, et al. “Accretion in Strong Field Gravity with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1007/s11433-018-9297-0\">https://doi.org/10.1007/s11433-018-9297-0</a>.","apa":"Rosa, A. D., Uttley, P., Gou, L., Liu, Y., Bambi, C., Barret, D., … Zhou, X. (2018). Accretion in strong field gravity with eXTP. <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11433-018-9297-0\">https://doi.org/10.1007/s11433-018-9297-0</a>","mla":"Rosa, Alessandra De, et al. “Accretion in Strong Field Gravity with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2, 29504, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1007/s11433-018-9297-0\">10.1007/s11433-018-9297-0</a>.","short":"A.D. Rosa, P. Uttley, L. Gou, Y. Liu, C. Bambi, D. Barret, T. Belloni, E. Berti, S. Bianchi, I. Caiazzo, P. Casella, M. Feroci, V. Ferrari, L. Gualtieri, J. Heyl, A. Ingram, V. Karas, F. Lu, B. Luo, G. Matt, S. Motta, J. Neilsen, P. Pani, A. Santangelo, X. Shu, J. Wang, J.-M. Wang, Y. Xue, Y. Xu, W. Yuan, Y. Yuan, S.-N. Zhang, S. Zhang, I. Agudo, L. Amati, N. Andersson, C. Baglio, P. Bakala, A. Baykal, S. Bhattacharyya, I. Bombaci, N. Bucciantini, F. Capitanio, R. Ciolfi, W.K. Cui, F. D’Ammando, T. Dauser, M. Del Santo, B. De Marco, T. Di Salvo, C. Done, M. Dovčiak, A.C. Fabian, M. Falanga, A.F. Gambino, B. Gendre, V. Grinberg, A. Heger, J. Homan, R. Iaria, J. Jiang, C. Jin, E. Koerding, M. Linares, Z. Liu, T.J. Maccarone, J. Malzac, A. Manousakis, F. Marin, A. Marinucci, M. Mehdipour, M. Méndez, S. Migliari, C. Miller, G. Miniutti, E. Nardini, P.T. O’Brien, J.P. Osborne, P.O. Petrucci, A. Possenti, A. Riggio, J. Rodriguez, A. Sanna, L. Shao, M. Sobolewska, E. Sramkova, A.L. Stevens, H. Stiele, G. Stratta, Z. Stuchlik, J. Svoboda, F. Tamburini, T.M. Tauris, F. Tombesi, G. Torok, M. Urbanec, F. Vincent, Q. Wu, F. Yuan, J.J.M. in’ t Zand, A.A. Zdziarski, X. Zhou, Science China Physics, Mechanics &#38; Astronomy 62 (2018).","ieee":"A. D. Rosa <i>et al.</i>, “Accretion in strong field gravity with eXTP,” <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2. Springer Nature, 2018.","ista":"Rosa AD et al. 2018. Accretion in strong field gravity with eXTP. Science China Physics, Mechanics &#38; Astronomy. 62(2), 29504.","ama":"Rosa AD, Uttley P, Gou L, et al. Accretion in strong field gravity with eXTP. <i>Science China Physics, Mechanics &#38; Astronomy</i>. 2018;62(2). doi:<a href=\"https://doi.org/10.1007/s11433-018-9297-0\">10.1007/s11433-018-9297-0</a>"},"day":"07","status":"public"},{"scopus_import":"1","_id":"15233","oa_version":"Preprint","intvolume":"        62","article_type":"original","type":"journal_article","date_published":"2018-10-08T00:00:00Z","month":"10","language":[{"iso":"eng"}],"date_updated":"2024-04-08T07:01:20Z","publisher":"Springer Nature","arxiv":1,"oa":1,"day":"08","status":"public","citation":{"short":"A. Santangelo, S. Zane, H. Feng, R. Xu, V. Doroshenko, E. Bozzo, I. Caiazzo, F.C. Zelati, P. Esposito, D. González-Caniulef, J. Heyl, D. Huppenkothen, G. Israel, Z. Li, L. Lin, R. Mignani, N. Rea, M. Orlandini, R. Taverna, H. Tong, R. Turolla, C. Baglio, F. Bernardini, N. Bucciantini, M. Feroci, F. Fürst, E. Göğüş, C. Güngör, L. Ji, F. Lu, A. Manousakis, S. Mereghetti, R. Mikusincova, B. Paul, C. Prescod-Weinstein, G. Younes, A. Tiengo, Y. Xu, A. Watts, S. Zhang, S.-N. Zhan, Science China Physics, Mechanics &#38; Astronomy 62 (2018).","ieee":"A. Santangelo <i>et al.</i>, “Physics and astrophysics of strong magnetic field systems with eXTP,” <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2. Springer Nature, 2018.","ama":"Santangelo A, Zane S, Feng H, et al. Physics and astrophysics of strong magnetic field systems with eXTP. <i>Science China Physics, Mechanics &#38; Astronomy</i>. 2018;62(2). doi:<a href=\"https://doi.org/10.1007/s11433-018-9234-3\">10.1007/s11433-018-9234-3</a>","ista":"Santangelo A, Zane S, Feng H, Xu R, Doroshenko V, Bozzo E, Caiazzo I, Zelati FC, Esposito P, González-Caniulef D, Heyl J, Huppenkothen D, Israel G, Li Z, Lin L, Mignani R, Rea N, Orlandini M, Taverna R, Tong H, Turolla R, Baglio C, Bernardini F, Bucciantini N, Feroci M, Fürst F, Göğüş E, Güngör C, Ji L, Lu F, Manousakis A, Mereghetti S, Mikusincova R, Paul B, Prescod-Weinstein C, Younes G, Tiengo A, Xu Y, Watts A, Zhang S, Zhan S-N. 2018. Physics and astrophysics of strong magnetic field systems with eXTP. Science China Physics, Mechanics &#38; Astronomy. 62(2), 29505.","apa":"Santangelo, A., Zane, S., Feng, H., Xu, R., Doroshenko, V., Bozzo, E., … Zhan, S.-N. (2018). Physics and astrophysics of strong magnetic field systems with eXTP. <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11433-018-9234-3\">https://doi.org/10.1007/s11433-018-9234-3</a>","chicago":"Santangelo, Andrea, Silvia Zane, Hua Feng, RenXin Xu, Victor Doroshenko, Enrico Bozzo, Ilaria Caiazzo, et al. “Physics and Astrophysics of Strong Magnetic Field Systems with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1007/s11433-018-9234-3\">https://doi.org/10.1007/s11433-018-9234-3</a>.","mla":"Santangelo, Andrea, et al. “Physics and Astrophysics of Strong Magnetic Field Systems with EXTP.” <i>Science China Physics, Mechanics &#38; Astronomy</i>, vol. 62, no. 2, 29505, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1007/s11433-018-9234-3\">10.1007/s11433-018-9234-3</a>."},"author":[{"last_name":"Santangelo","first_name":"Andrea","full_name":"Santangelo, Andrea"},{"first_name":"Silvia","last_name":"Zane","full_name":"Zane, Silvia"},{"full_name":"Feng, Hua","first_name":"Hua","last_name":"Feng"},{"full_name":"Xu, RenXin","first_name":"RenXin","last_name":"Xu"},{"first_name":"Victor","last_name":"Doroshenko","full_name":"Doroshenko, Victor"},{"last_name":"Bozzo","first_name":"Enrico","full_name":"Bozzo, Enrico"},{"full_name":"Caiazzo, Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","last_name":"Caiazzo","first_name":"Ilaria"},{"first_name":"Francesco Coti","last_name":"Zelati","full_name":"Zelati, Francesco Coti"},{"last_name":"Esposito","first_name":"Paolo","full_name":"Esposito, Paolo"},{"full_name":"González-Caniulef, Denis","first_name":"Denis","last_name":"González-Caniulef"},{"full_name":"Heyl, Jeremy","last_name":"Heyl","first_name":"Jeremy"},{"last_name":"Huppenkothen","first_name":"Daniela","full_name":"Huppenkothen, Daniela"},{"last_name":"Israel","first_name":"Gianluca","full_name":"Israel, Gianluca"},{"last_name":"Li","first_name":"ZhaoSheng","full_name":"Li, ZhaoSheng"},{"full_name":"Lin, Lin","first_name":"Lin","last_name":"Lin"},{"last_name":"Mignani","first_name":"Roberto","full_name":"Mignani, Roberto"},{"first_name":"Nanda","last_name":"Rea","full_name":"Rea, Nanda"},{"last_name":"Orlandini","first_name":"Mauro","full_name":"Orlandini, Mauro"},{"last_name":"Taverna","first_name":"Roberto","full_name":"Taverna, Roberto"},{"full_name":"Tong, Hao","first_name":"Hao","last_name":"Tong"},{"full_name":"Turolla, Roberto","first_name":"Roberto","last_name":"Turolla"},{"full_name":"Baglio, Cristina","last_name":"Baglio","first_name":"Cristina"},{"full_name":"Bernardini, Federico","first_name":"Federico","last_name":"Bernardini"},{"first_name":"Niccolo’","last_name":"Bucciantini","full_name":"Bucciantini, Niccolo’"},{"full_name":"Feroci, Marco","first_name":"Marco","last_name":"Feroci"},{"full_name":"Fürst, Felix","last_name":"Fürst","first_name":"Felix"},{"first_name":"Ersin","last_name":"Göğüş","full_name":"Göğüş, Ersin"},{"last_name":"Güngör","first_name":"Can","full_name":"Güngör, Can"},{"first_name":"Long","last_name":"Ji","full_name":"Ji, Long"},{"full_name":"Lu, FangJun","last_name":"Lu","first_name":"FangJun"},{"full_name":"Manousakis, Antonios","last_name":"Manousakis","first_name":"Antonios"},{"first_name":"Sandro","last_name":"Mereghetti","full_name":"Mereghetti, Sandro"},{"first_name":"Romana","last_name":"Mikusincova","full_name":"Mikusincova, Romana"},{"first_name":"Biswajit","last_name":"Paul","full_name":"Paul, Biswajit"},{"first_name":"Chanda","last_name":"Prescod-Weinstein","full_name":"Prescod-Weinstein, Chanda"},{"last_name":"Younes","first_name":"George","full_name":"Younes, George"},{"full_name":"Tiengo, Andrea","last_name":"Tiengo","first_name":"Andrea"},{"first_name":"YuPeng","last_name":"Xu","full_name":"Xu, YuPeng"},{"full_name":"Watts, Anna","last_name":"Watts","first_name":"Anna"},{"full_name":"Zhang, Shu","first_name":"Shu","last_name":"Zhang"},{"full_name":"Zhan, Shuang-Nan","first_name":"Shuang-Nan","last_name":"Zhan"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","volume":62,"keyword":["General Physics and Astronomy"],"title":"Physics and astrophysics of strong magnetic field systems with eXTP","article_processing_charge":"No","external_id":{"arxiv":["1812.04460"]},"publication_status":"published","abstract":[{"text":"In this paper we present the science potential of the enhanced X-ray Timing and Polarimetry (eXTP) mission for studies of strongly magnetized objects. We will focus on the physics and astrophysics of strongly magnetized objects, namely magnetars, accreting X-ray pulsars, and rotation powered pulsars. We also discuss the science potential of eXTP for QED studies. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Sciences, the eXTP mission is expected to be launched in the mid 2020s.","lang":"eng"}],"publication_identifier":{"eissn":["1869-1927"],"issn":["1674-7348"]},"doi":"10.1007/s11433-018-9234-3","issue":"2","publication":"Science China Physics, Mechanics & Astronomy","date_created":"2024-03-26T10:38:05Z","year":"2018","article_number":"29505","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1812.04460","open_access":"1"}],"quality_controlled":"1"},{"day":"07","status":"public","citation":{"short":"S. Chen, H. Richer, I. Caiazzo, J. Heyl, The Astrophysical Journal 867 (2018).","ieee":"S. Chen, H. Richer, I. Caiazzo, and J. Heyl, “Distances to the globular clusters 47 Tucanae and NGC 362 using Gaia DR2 parallaxes,” <i>The Astrophysical Journal</i>, vol. 867, no. 2. American Astronomical Society, 2018.","ista":"Chen S, Richer H, Caiazzo I, Heyl J. 2018. Distances to the globular clusters 47 Tucanae and NGC 362 using Gaia DR2 parallaxes. The Astrophysical Journal. 867(2), 132.","ama":"Chen S, Richer H, Caiazzo I, Heyl J. Distances to the globular clusters 47 Tucanae and NGC 362 using Gaia DR2 parallaxes. <i>The Astrophysical Journal</i>. 2018;867(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/aae089\">10.3847/1538-4357/aae089</a>","chicago":"Chen, Seery, Harvey Richer, Ilaria Caiazzo, and Jeremy Heyl. “Distances to the Globular Clusters 47 Tucanae and NGC 362 Using Gaia DR2 Parallaxes.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2018. <a href=\"https://doi.org/10.3847/1538-4357/aae089\">https://doi.org/10.3847/1538-4357/aae089</a>.","apa":"Chen, S., Richer, H., Caiazzo, I., &#38; Heyl, J. (2018). Distances to the globular clusters 47 Tucanae and NGC 362 using Gaia DR2 parallaxes. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.3847/1538-4357/aae089\">https://doi.org/10.3847/1538-4357/aae089</a>","mla":"Chen, Seery, et al. “Distances to the Globular Clusters 47 Tucanae and NGC 362 Using Gaia DR2 Parallaxes.” <i>The Astrophysical Journal</i>, vol. 867, no. 2, 132, American Astronomical Society, 2018, doi:<a href=\"https://doi.org/10.3847/1538-4357/aae089\">10.3847/1538-4357/aae089</a>."},"type":"journal_article","article_type":"original","intvolume":"       867","oa_version":"Preprint","_id":"15234","scopus_import":"1","oa":1,"arxiv":1,"publisher":"American Astronomical Society","date_updated":"2024-04-08T07:01:51Z","language":[{"iso":"eng"}],"month":"11","date_published":"2018-11-07T00:00:00Z","article_number":"132","year":"2018","date_created":"2024-03-26T10:38:28Z","publication":"The Astrophysical Journal","issue":"2","doi":"10.3847/1538-4357/aae089","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]},"quality_controlled":"1","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1807.07089","open_access":"1"}],"volume":867,"extern":"1","author":[{"last_name":"Chen","first_name":"Seery","full_name":"Chen, Seery"},{"last_name":"Richer","first_name":"Harvey","full_name":"Richer, Harvey"},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","full_name":"Caiazzo, Ilaria","last_name":"Caiazzo","first_name":"Ilaria"},{"full_name":"Heyl, Jeremy","first_name":"Jeremy","last_name":"Heyl"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Using parallaxes from Gaia Data Release 2 (Gaia DR2), we estimate the distance to the globular clusters 47 Tuc and NGC 362, taking advantage of the background stars in the Small Magellanic Cloud and quasars to account for various parallax systematics. We found the parallax to be dependent on the Gaia DR2 G-band apparent magnitude for stars with 13 < G < 18, where brighter stars have a lower parallax zero point than fainter stars. The distance to 47 Tuc was found to be 4.45 ± 0.01 ± 0.12 kpc, and for NGC 362 8.54 ± 0.20 ± 0.44 kpc, with random and systematic errors listed, respectively. This is the first time a precise distance measurement directly using parallaxes has been determined for either of these two globular clusters.","lang":"eng"}],"external_id":{"arxiv":["1807.07089"]},"publication_status":"published","article_processing_charge":"No","title":"Distances to the globular clusters 47 Tucanae and NGC 362 using Gaia DR2 parallaxes","keyword":["Space and Planetary Science","Astronomy and Astrophysics"]},{"citation":{"mla":"Heyl, Jeremy, and Ilaria Caiazzo. “Strongly Magnetized Sources: QED and X-Ray Polarization.” <i>Galaxies</i>, vol. 6, no. 3, 76, MDPI, 2018, doi:<a href=\"https://doi.org/10.3390/galaxies6030076\">10.3390/galaxies6030076</a>.","chicago":"Heyl, Jeremy, and Ilaria Caiazzo. “Strongly Magnetized Sources: QED and X-Ray Polarization.” <i>Galaxies</i>. MDPI, 2018. <a href=\"https://doi.org/10.3390/galaxies6030076\">https://doi.org/10.3390/galaxies6030076</a>.","apa":"Heyl, J., &#38; Caiazzo, I. (2018). Strongly magnetized sources: QED and X-ray polarization. <i>Galaxies</i>. MDPI. <a href=\"https://doi.org/10.3390/galaxies6030076\">https://doi.org/10.3390/galaxies6030076</a>","ista":"Heyl J, Caiazzo I. 2018. Strongly magnetized sources: QED and X-ray polarization. Galaxies. 6(3), 76.","ama":"Heyl J, Caiazzo I. Strongly magnetized sources: QED and X-ray polarization. <i>Galaxies</i>. 2018;6(3). doi:<a href=\"https://doi.org/10.3390/galaxies6030076\">10.3390/galaxies6030076</a>","ieee":"J. Heyl and I. Caiazzo, “Strongly magnetized sources: QED and X-ray polarization,” <i>Galaxies</i>, vol. 6, no. 3. MDPI, 2018.","short":"J. Heyl, I. Caiazzo, Galaxies 6 (2018)."},"status":"public","day":"21","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"month":"07","language":[{"iso":"eng"}],"date_published":"2018-07-21T00:00:00Z","publisher":"MDPI","arxiv":1,"date_updated":"2024-04-08T07:02:25Z","oa":1,"_id":"15235","scopus_import":"1","article_type":"original","intvolume":"         6","oa_version":"Published Version","type":"journal_article","main_file_link":[{"url":"https://doi.org/10.3390/galaxies6030076","open_access":"1"}],"quality_controlled":"1","issue":"3","doi":"10.3390/galaxies6030076","publication_identifier":{"eissn":["2075-4434"]},"publication":"Galaxies","year":"2018","date_created":"2024-03-26T10:38:46Z","article_number":"76","title":"Strongly magnetized sources: QED and X-ray polarization","keyword":["Astronomy and Astrophysics"],"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Radiative corrections of quantum electrodynamics cause a vacuum threaded by a magnetic field to be birefringent. This means that radiation of different polarizations travels at different speeds. Even in the strong magnetic fields of astrophysical sources, the difference in speed is small. However, it has profound consequences for the extent of polarization expected from strongly magnetized sources. We demonstrate how the birefringence arises from first principles, show how birefringence affects the polarization state of radiation and present recent calculations for the expected polarization from magnetars and X-ray pulsars."}],"external_id":{"arxiv":["1802.00358"]},"publication_status":"published","extern":"1","author":[{"full_name":"Heyl, Jeremy","last_name":"Heyl","first_name":"Jeremy"},{"id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388","full_name":"Caiazzo, Ilaria","first_name":"Ilaria","last_name":"Caiazzo"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":6},{"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1802.08248","open_access":"1"}],"quality_controlled":"1","publication":"Monthly Notices of the Royal Astronomical Society","issue":"4","doi":"10.1093/mnras/sty482","publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"year":"2018","date_created":"2024-03-26T10:39:05Z","title":"PSR J1755−2550: A young radio pulsar with a massive, compact companion","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"abstract":[{"text":"Radio pulsars found in binary systems with short orbital periods are usually fast spinning as a consequence of recycling via mass transfer from their companion stars; this process is also thought to decrease the magnetic field of the neutron star being recycled. Here, we report on timing observations of the recently discovered binary PSR J1755−2550 and find that this pulsar is an exception: with a characteristic age of 2.1 Myr, it is relatively young; furthermore, with a spin period of 315 ms and a surface magnetic field strength at its poles of 0.88 × 1012 G, the pulsar shows no sign of having been recycled. Based on its timing and orbital characteristics, the pulsar either has a massive white dwarf (WD) or a neutron star (NS) companion. To distinguish between these two cases, we searched radio observations for a potential recycled pulsar companion and analysed archival optical data for a potential WD companion. Neither work returned conclusive detections. We apply population synthesis modelling and find that both solutions are roughly equally probable. Our population synthesis also predicts a minimum mass of 0.90 M⊙ for the companion star to PSR J1755−2550 and we simulate the systemic runaway velocities for the resulting WDNS systems which may merge and possibly produce Ca-rich supernovae. Whether PSR J1755−2550 hosts a WD or a NS companion star, it is certainly a member of a rare subpopulation of binary radio pulsars.","lang":"eng"}],"external_id":{"arxiv":["1802.08248"]},"publication_status":"published","page":"4315-4326","article_processing_charge":"No","volume":476,"extern":"1","author":[{"first_name":"C","last_name":"Ng","full_name":"Ng, C"},{"full_name":"Kruckow, M U","first_name":"M U","last_name":"Kruckow"},{"last_name":"Tauris","first_name":"T M","full_name":"Tauris, T M"},{"full_name":"Lyne, A G","first_name":"A G","last_name":"Lyne"},{"full_name":"Freire, P C C","first_name":"P C C","last_name":"Freire"},{"full_name":"Ridolfi, A","first_name":"A","last_name":"Ridolfi"},{"last_name":"Caiazzo","first_name":"Ilaria","full_name":"Caiazzo, Ilaria","orcid":"0000-0002-4770-5388","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d"},{"full_name":"Heyl, J","first_name":"J","last_name":"Heyl"},{"full_name":"Kramer, M","last_name":"Kramer","first_name":"M"},{"full_name":"Cameron, A D","last_name":"Cameron","first_name":"A D"},{"last_name":"Champion","first_name":"D J","full_name":"Champion, D J"},{"last_name":"Stappers","first_name":"B","full_name":"Stappers, B"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Ng, C., et al. “PSR J1755−2550: A Young Radio Pulsar with a Massive, Compact Companion.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 476, no. 4, Oxford University Press, 2018, pp. 4315–26, doi:<a href=\"https://doi.org/10.1093/mnras/sty482\">10.1093/mnras/sty482</a>.","chicago":"Ng, C, M U Kruckow, T M Tauris, A G Lyne, P C C Freire, A Ridolfi, Ilaria Caiazzo, et al. “PSR J1755−2550: A Young Radio Pulsar with a Massive, Compact Companion.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2018. <a href=\"https://doi.org/10.1093/mnras/sty482\">https://doi.org/10.1093/mnras/sty482</a>.","apa":"Ng, C., Kruckow, M. U., Tauris, T. M., Lyne, A. G., Freire, P. C. C., Ridolfi, A., … Stappers, B. (2018). PSR J1755−2550: A young radio pulsar with a massive, compact companion. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/sty482\">https://doi.org/10.1093/mnras/sty482</a>","ista":"Ng C, Kruckow MU, Tauris TM, Lyne AG, Freire PCC, Ridolfi A, Caiazzo I, Heyl J, Kramer M, Cameron AD, Champion DJ, Stappers B. 2018. PSR J1755−2550: A young radio pulsar with a massive, compact companion. Monthly Notices of the Royal Astronomical Society. 476(4), 4315–4326.","ama":"Ng C, Kruckow MU, Tauris TM, et al. PSR J1755−2550: A young radio pulsar with a massive, compact companion. <i>Monthly Notices of the Royal Astronomical Society</i>. 2018;476(4):4315-4326. doi:<a href=\"https://doi.org/10.1093/mnras/sty482\">10.1093/mnras/sty482</a>","ieee":"C. Ng <i>et al.</i>, “PSR J1755−2550: A young radio pulsar with a massive, compact companion,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 476, no. 4. Oxford University Press, pp. 4315–4326, 2018.","short":"C. Ng, M.U. Kruckow, T.M. Tauris, A.G. Lyne, P.C.C. Freire, A. Ridolfi, I. Caiazzo, J. Heyl, M. Kramer, A.D. Cameron, D.J. Champion, B. Stappers, Monthly Notices of the Royal Astronomical Society 476 (2018) 4315–4326."},"status":"public","day":"23","publisher":"Oxford University Press","arxiv":1,"date_updated":"2024-04-08T07:02:52Z","month":"02","language":[{"iso":"eng"}],"date_published":"2018-02-23T00:00:00Z","oa":1,"_id":"15236","scopus_import":"1","type":"journal_article","article_type":"original","oa_version":"Preprint","intvolume":"       476"}]