---
_id: '5556'
abstract:
- lang: eng
text: "MATLAB code and processed datasets available for reproducing the results
in: \r\nLukačišin, M.*, Landon, M.*, Jajoo, R*. (2016) Sequence-Specific Thermodynamic
Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking
in Yeast.\r\n*equal contributions"
article_processing_charge: No
author:
- first_name: Martin
full_name: Lukacisin, Martin
id: 298FFE8C-F248-11E8-B48F-1D18A9856A87
last_name: Lukacisin
orcid: 0000-0001-6549-4177
- first_name: Matthieu
full_name: Landon, Matthieu
last_name: Landon
- first_name: Rishi
full_name: Jajoo, Rishi
last_name: Jajoo
citation:
ama: Lukacisin M, Landon M, Jajoo R. MATLAB analysis code for “Sequence-Specific
Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
and Backtracking in Yeast.” 2016. doi:10.15479/AT:ISTA:45
apa: Lukacisin, M., Landon, M., & Jajoo, R. (2016). MATLAB analysis code for
“Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional
Pausing and Backtracking in Yeast.” Institute of Science and Technology Austria.
https://doi.org/10.15479/AT:ISTA:45
chicago: Lukacisin, Martin, Matthieu Landon, and Rishi Jajoo. “MATLAB Analysis Code
for ‘Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both
Transcriptional Pausing and Backtracking in Yeast.’” Institute of Science and
Technology Austria, 2016. https://doi.org/10.15479/AT:ISTA:45.
ieee: M. Lukacisin, M. Landon, and R. Jajoo, “MATLAB analysis code for ‘Sequence-Specific
Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
and Backtracking in Yeast.’” Institute of Science and Technology Austria, 2016.
ista: Lukacisin M, Landon M, Jajoo R. 2016. MATLAB analysis code for ‘Sequence-Specific
Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
and Backtracking in Yeast’, Institute of Science and Technology Austria, 10.15479/AT:ISTA:45.
mla: Lukacisin, Martin, et al. MATLAB Analysis Code for “Sequence-Specific Thermodynamic
Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking
in Yeast.” Institute of Science and Technology Austria, 2016, doi:10.15479/AT:ISTA:45.
short: M. Lukacisin, M. Landon, R. Jajoo, (2016).
datarep_id: '45'
date_created: 2018-12-12T12:31:31Z
date_published: 2016-08-25T00:00:00Z
date_updated: 2024-02-21T13:51:53Z
day: '25'
ddc:
- '571'
department:
- _id: ToBo
doi: 10.15479/AT:ISTA:45
file:
- access_level: open_access
checksum: ee697f2b1ade4dc14d6ac0334dd832ab
content_type: application/zip
creator: system
date_created: 2018-12-12T13:02:58Z
date_updated: 2020-07-14T12:47:02Z
file_id: '5616'
file_name: IST-2016-45-v1+1_PaperCode.zip
file_size: 296722548
relation: main_file
file_date_updated: 2020-07-14T12:47:02Z
has_accepted_license: '1'
keyword:
- transcription
- pausing
- backtracking
- polymerase
- RNA
- NET-seq
- nucleosome
- basepairing
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '08'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '8431'
relation: used_in_publication
status: deleted
- id: '1029'
relation: research_paper
status: public
status: public
title: MATLAB analysis code for 'Sequence-Specific Thermodynamic Properties of Nucleic
Acids Influence Both Transcriptional Pausing and Backtracking in Yeast'
tmp:
image: /images/cc_by_sa.png
legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
BY-SA 4.0)
short: CC BY-SA (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '15245'
abstract:
- lang: eng
text: 'eXTP is a science mission designed to study the state of matter under extreme
conditions of density, gravity and magnetism. Primary goals are the determination
of the equation of state of matter at supra-nuclear density, the measurement of
QED effects in highly magnetized star, and the study of accretion in the strong-field
regime of gravity. Primary targets include isolated and binary neutron stars,
strong magnetic field systems like magnetars, and stellar-mass and supermassive
black holes. The mission carries a unique and unprecedented suite of state-of-the-art
scientific instruments enabling for the first time ever the simultaneous spectral-timing-polarimetry
studies of cosmic sources in the energy range from 0.5-30 keV (and beyond). Key
elements of the payload are: the Spectroscopic Focusing Array (SFA) - a set of
11 X-ray optics for a total effective area of ∼0.9 m2 and 0.6 m2 at 2 keV and
6 keV respectively, equipped with Silicon Drift Detectors offering <180 eV spectral
resolution; the Large Area Detector (LAD) - a deployable set of 640 Silicon Drift
Detectors, for a total effective area of ∼3.4 m2, between 6 and 10 keV, and spectral
resolution better than 250 eV; the Polarimetry Focusing Array (PFA) - a set of
2 X-ray telescope, for a total effective area of 250 cm2 at 2 keV, equipped with
imaging gas pixel photoelectric polarimeters; the Wide Field Monitor (WFM) - a
set of 3 coded mask wide field units, equipped with position-sensitive Silicon
Drift Detectors, each covering a 90 degrees x 90 degrees field of view. The eXTP
international consortium includes major institutions of the Chinese Academy of
Sciences and Universities in China, as well as major institutions in several European
countries and the United States. The predecessor of eXTP, the XTP mission concept,
has been selected and funded as one of the so-called background missions in the
Strategic Priority Space Science Program of the Chinese Academy of Sciences since
2011. The strong European participation has significantly enhanced the scientific
capabilities of eXTP. The planned launch date of the mission is earlier than 2025.'
article_number: '99051Q '
article_processing_charge: No
author:
- first_name: S. N.
full_name: Zhang, S. N.
last_name: Zhang
- first_name: M.
full_name: Feroci, M.
last_name: Feroci
- first_name: A.
full_name: Santangelo, A.
last_name: Santangelo
- first_name: Y. W.
full_name: Dong, Y. W.
last_name: Dong
- first_name: H.
full_name: Feng, H.
last_name: Feng
- first_name: F. J.
full_name: Lu, F. J.
last_name: Lu
- first_name: K.
full_name: Nandra, K.
last_name: Nandra
- first_name: Z. S.
full_name: Wang, Z. S.
last_name: Wang
- first_name: S.
full_name: Zhang, S.
last_name: Zhang
- first_name: E.
full_name: Bozzo, E.
last_name: Bozzo
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full_name: Brandt, S.
last_name: Brandt
- first_name: A.
full_name: De Rosa, A.
last_name: De Rosa
- first_name: L. J.
full_name: Gou, L. J.
last_name: Gou
- first_name: M.
full_name: Hernanz, M.
last_name: Hernanz
- first_name: M.
full_name: van der Klis, M.
last_name: van der Klis
- first_name: X. D.
full_name: Li, X. D.
last_name: Li
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full_name: Liu, Y.
last_name: Liu
- first_name: P.
full_name: Orleanski, P.
last_name: Orleanski
- first_name: G.
full_name: Pareschi, G.
last_name: Pareschi
- first_name: M.
full_name: Pohl, M.
last_name: Pohl
- first_name: J.
full_name: Poutanen, J.
last_name: Poutanen
- first_name: J. L.
full_name: Qu, J. L.
last_name: Qu
- first_name: S.
full_name: Schanne, S.
last_name: Schanne
- first_name: L.
full_name: Stella, L.
last_name: Stella
- first_name: P.
full_name: Uttley, P.
last_name: Uttley
- first_name: A.
full_name: Watts, A.
last_name: Watts
- first_name: R. X.
full_name: Xu, R. X.
last_name: Xu
- first_name: W. F.
full_name: Yu, W. F.
last_name: Yu
- first_name: J. J. M.
full_name: in ’t Zand, J. J. M.
last_name: in ’t Zand
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full_name: Zane, S.
last_name: Zane
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full_name: Alvarez, L.
last_name: Alvarez
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full_name: Amati, L.
last_name: Amati
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full_name: Baldini, L.
last_name: Baldini
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full_name: Bambi, C.
last_name: Bambi
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full_name: Basso, S.
last_name: Basso
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full_name: Bhattacharyya, S.
last_name: Bhattacharyya
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full_name: Bellazzini, R.
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full_name: Burwitz, V.
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full_name: Budtz-Jørgensen, C.
last_name: Budtz-Jørgensen
- first_name: Ilaria
full_name: Caiazzo, Ilaria
id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
last_name: Caiazzo
orcid: 0000-0002-4770-5388
- first_name: R.
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full_name: Donnarumma, I.
last_name: Donnarumma
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last_name: Doroshenko
- first_name: P.
full_name: Esposito, P.
last_name: Esposito
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full_name: Evangelista, Y.
last_name: Evangelista
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full_name: Favre, Y.
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last_name: Galvez
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last_name: Goetz
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citation:
ama: 'Zhang SN, Feroci M, Santangelo A, et al. eXTP: Enhanced X-ray timing and polarization
mission. In: Proceedings of the SPIE. Vol 9905. SPIE; 2016. doi:10.1117/12.2232034'
apa: 'Zhang, S. N., Feroci, M., Santangelo, A., Dong, Y. W., Feng, H., Lu, F. J.,
… Zhou, X. L. (2016). eXTP: Enhanced X-ray timing and polarization mission. In
Proceedings of the SPIE (Vol. 9905). SPIE. https://doi.org/10.1117/12.2232034'
chicago: 'Zhang, S. N., M. Feroci, A. Santangelo, Y. W. Dong, H. Feng, F. J. Lu,
K. Nandra, et al. “EXTP: Enhanced X-Ray Timing and Polarization Mission.” In Proceedings
of the SPIE, Vol. 9905. SPIE, 2016. https://doi.org/10.1117/12.2232034.'
ieee: 'S. N. Zhang et al., “eXTP: Enhanced X-ray timing and polarization
mission,” in Proceedings of the SPIE, 2016, vol. 9905.'
ista: 'Zhang SN et al. 2016. eXTP: Enhanced X-ray timing and polarization mission.
Proceedings of the SPIE. vol. 9905, 99051Q.'
mla: 'Zhang, S. N., et al. “EXTP: Enhanced X-Ray Timing and Polarization Mission.”
Proceedings of the SPIE, vol. 9905, 99051Q, SPIE, 2016, doi:10.1117/12.2232034.'
short: S.N. Zhang, M. Feroci, A. Santangelo, Y.W. Dong, H. Feng, F.J. Lu, K. Nandra,
Z.S. Wang, S. Zhang, E. Bozzo, S. Brandt, A. De Rosa, L.J. Gou, M. Hernanz, M.
van der Klis, X.D. Li, Y. Liu, P. Orleanski, G. Pareschi, M. Pohl, J. Poutanen,
J.L. Qu, S. Schanne, L. Stella, P. Uttley, A. Watts, R.X. Xu, W.F. Yu, J.J.M.
in ’t Zand, S. Zane, L. Alvarez, L. Amati, L. Baldini, C. Bambi, S. Basso, S.
Bhattacharyya, R. Bellazzini, T. Belloni, P. Bellutti, S. Bianchi, A. Brez, M.
Bursa, V. Burwitz, C. Budtz-Jørgensen, I. Caiazzo, R. Campana, X.L. Cao, P. Casella,
C.Y. Chen, L. Chen, T. Chen, Y. Chen, Y. Chen, Y.P. Chen, M. Civitani, F. Coti
Zelati, W. Cui, W.W. Cui, Z.G. Dai, E. Del Monte, D. de Martino, S. Di Cosimo,
S. Diebold, M. Dovciak, I. Donnarumma, V. Doroshenko, P. Esposito, Y. Evangelista,
Y. Favre, P. Friedrich, F. Fuschino, J.L. Galvez, Z.L. Gao, M.Y. Ge, O. Gevin,
D. Goetz, D.W. Han, J. Heyl, J. Horak, W. Hu, F. Huang, Q.S. Huang, R. Hudec,
D. Huppenkothen, G.L. Israel, A. Ingram, V. Karas, D. Karelin, P.A. Jenke, L.
Ji, S. Korpela, D. Kunneriath, C. Labanti, G. Li, X. Li, Z.S. Li, E.W. Liang,
O. Limousin, L. Lin, Z.X. Ling, H.B. Liu, H.W. Liu, Z. Liu, B. Lu, N. Lund, D.
Lai, B. Luo, T. Luo, B. Ma, S. Mahmoodifar, M. Marisaldi, A. Martindale, N. Meidinger,
Y.P. Men, M. Michalska, R. Mignani, M. Minuti, S. Motta, F. Muleri, J. Neilsen,
M. Orlandini, A.T. Pan, A. Patruno, E. Perinati, A. Picciotto, C. Piemonte, M.
Pinchera, A. Rachevski, M. Rapisarda, N. Rea, E.M.R. Rossi, A. Rubini, G. Sala,
X.W. Shu, C. Sgro, Z.X. Shen, P. Soffitta, L.M. Song, G. Spandre, G. Stratta,
T.E. Strohmayer, L. Sun, J. Svoboda, G. Tagliaferri, C. Tenzer, T. Hong, R. Taverna,
G. Torok, R. Turolla, S. Vacchi, J. Wang, D. Walton, K. Wang, J.F. Wang, R.J.
Wang, Y.F. Wang, S.S. Weng, J. Wilms, B. Winter, X. Wu, X.F. Wu, S.L. Xiong, Y.P.
Xu, Y.Q. Xue, Z. Yan, S. Yang, X. Yang, Y.J. Yang, F. Yuan, W.M. Yuan, Y.F. Yuan,
G. Zampa, N. Zampa, A. Zdziarski, C. Zhang, C.L. Zhang, L. Zhang, X. Zhang, Z.
Zhang, W.D. Zhang, S.J. Zheng, P. Zhou, X.L. Zhou, in:, Proceedings of the SPIE,
SPIE, 2016.
date_created: 2024-03-26T10:42:21Z
date_published: 2016-07-01T00:00:00Z
date_updated: 2024-03-27T08:23:11Z
day: '01'
doi: 10.1117/12.2232034
extern: '1'
external_id:
arxiv:
- '1607.08823'
intvolume: ' 9905'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1607.08823
month: '07'
oa: 1
oa_version: Preprint
publication: Proceedings of the SPIE
publication_identifier:
issn:
- 0277-786X
publication_status: published
publisher: SPIE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'eXTP: Enhanced X-ray timing and polarization mission'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9905
year: '2016'
...
---
_id: '1183'
abstract:
- lang: eng
text: Autism spectrum disorders (ASD) are a group of genetic disorders often overlapping
with other neurological conditions. We previously described abnormalities in the
branched-chain amino acid (BCAA) catabolic pathway as a cause of ASD. Here, we
show that the solute carrier transporter 7a5 (SLC7A5), a large neutral amino acid
transporter localized at the blood brain barrier (BBB), has an essential role
in maintaining normal levels of brain BCAAs. In mice, deletion of Slc7a5 from
the endothelial cells of the BBB leads to atypical brain amino acid profile, abnormal
mRNA translation, and severe neurological abnormalities. Furthermore, we identified
several patients with autistic traits and motor delay carrying deleterious homozygous
mutations in the SLC7A5 gene. Finally, we demonstrate that BCAA intracerebroventricular
administration ameliorates abnormal behaviors in adult mutant mice. Our data elucidate
a neurological syndrome defined by SLC7A5 mutations and support an essential role
for the BCAA in human brain function.
acknowledgement: "This work was supported by NICHD (P01HD070494) and SFARI (grant
275275) to J.G.G., and FWF (SFB35_3523) to G.N.\r\nWe thank A.C. Manzano, Mike Liu,
and F. Marr for technical assistance, and R. Shigemoto and the IST Austria Electron
Microscopy (EM) Facility for assistance. We acknowledge support from CIDR for genome-wide
SNP analysis (X01HG008823) and Broad Institute Center for Mendelian Disorders (UM1HG008900
to D. MacArthur), the Yale Center for Mendelian Disorders (U54HG006504 to M.G.),
the Gregory M. Kiez and Mehmet Kutman Foundation (M.G.), Italian Ministry of Instruction
University and Research (PON01_00937 to C.I.), and NIH (R01-GM108911 to A.S.). This
work was supported by NICHD (P01HD070494) and SFARI (grant 275275) to J.G.G., and
FWF (SFB35_3523) to G.N.\r\n\r\n#EMFacility"
article_processing_charge: No
article_type: original
author:
- first_name: Dora-Clara
full_name: Tarlungeanu, Dora-Clara
id: 2ABCE612-F248-11E8-B48F-1D18A9856A87
last_name: Tarlungeanu
- first_name: Elena
full_name: Deliu, Elena
id: 37A40D7E-F248-11E8-B48F-1D18A9856A87
last_name: Deliu
orcid: 0000-0002-7370-5293
- first_name: Christoph
full_name: Dotter, Christoph
id: 4C66542E-F248-11E8-B48F-1D18A9856A87
last_name: Dotter
orcid: 0000-0002-9033-9096
- first_name: Majdi
full_name: Kara, Majdi
last_name: Kara
- first_name: Philipp
full_name: Janiesch, Philipp
last_name: Janiesch
- first_name: Mariafrancesca
full_name: Scalise, Mariafrancesca
last_name: Scalise
- first_name: Michele
full_name: Galluccio, Michele
last_name: Galluccio
- first_name: Mateja
full_name: Tesulov, Mateja
last_name: Tesulov
- first_name: Emanuela
full_name: Morelli, Emanuela
id: 3F4D1282-F248-11E8-B48F-1D18A9856A87
last_name: Morelli
- first_name: Fatma
full_name: Sönmez, Fatma
last_name: Sönmez
- first_name: Kaya
full_name: Bilgüvar, Kaya
last_name: Bilgüvar
- first_name: Ryuichi
full_name: Ohgaki, Ryuichi
last_name: Ohgaki
- first_name: Yoshikatsu
full_name: Kanai, Yoshikatsu
last_name: Kanai
- first_name: Anide
full_name: Johansen, Anide
last_name: Johansen
- first_name: Seham
full_name: Esharif, Seham
last_name: Esharif
- first_name: Tawfeg
full_name: Ben Omran, Tawfeg
last_name: Ben Omran
- first_name: Meral
full_name: Topcu, Meral
last_name: Topcu
- first_name: Avner
full_name: Schlessinger, Avner
last_name: Schlessinger
- first_name: Cesare
full_name: Indiveri, Cesare
last_name: Indiveri
- first_name: Kent
full_name: Duncan, Kent
last_name: Duncan
- first_name: Ahmet
full_name: Caglayan, Ahmet
last_name: Caglayan
- first_name: Murat
full_name: Günel, Murat
last_name: Günel
- first_name: Joseph
full_name: Gleeson, Joseph
last_name: Gleeson
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
citation:
ama: Tarlungeanu D-C, Deliu E, Dotter C, et al. Impaired amino acid transport at
the blood brain barrier is a cause of autism spectrum disorder. Cell. 2016;167(6):1481-1494.
doi:10.1016/j.cell.2016.11.013
apa: Tarlungeanu, D.-C., Deliu, E., Dotter, C., Kara, M., Janiesch, P., Scalise,
M., … Novarino, G. (2016). Impaired amino acid transport at the blood brain barrier
is a cause of autism spectrum disorder. Cell. Cell Press. https://doi.org/10.1016/j.cell.2016.11.013
chicago: Tarlungeanu, Dora-Clara, Elena Deliu, Christoph Dotter, Majdi Kara, Philipp
Janiesch, Mariafrancesca Scalise, Michele Galluccio, et al. “Impaired Amino Acid
Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.”
Cell. Cell Press, 2016. https://doi.org/10.1016/j.cell.2016.11.013.
ieee: D.-C. Tarlungeanu et al., “Impaired amino acid transport at the blood
brain barrier is a cause of autism spectrum disorder,” Cell, vol. 167,
no. 6. Cell Press, pp. 1481–1494, 2016.
ista: Tarlungeanu D-C, Deliu E, Dotter C, Kara M, Janiesch P, Scalise M, Galluccio
M, Tesulov M, Morelli E, Sönmez F, Bilgüvar K, Ohgaki R, Kanai Y, Johansen A,
Esharif S, Ben Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan K, Caglayan
A, Günel M, Gleeson J, Novarino G. 2016. Impaired amino acid transport at the
blood brain barrier is a cause of autism spectrum disorder. Cell. 167(6), 1481–1494.
mla: Tarlungeanu, Dora-Clara, et al. “Impaired Amino Acid Transport at the Blood
Brain Barrier Is a Cause of Autism Spectrum Disorder.” Cell, vol. 167,
no. 6, Cell Press, 2016, pp. 1481–94, doi:10.1016/j.cell.2016.11.013.
short: D.-C. Tarlungeanu, E. Deliu, C. Dotter, M. Kara, P. Janiesch, M. Scalise,
M. Galluccio, M. Tesulov, E. Morelli, F. Sönmez, K. Bilgüvar, R. Ohgaki, Y. Kanai,
A. Johansen, S. Esharif, T. Ben Omran, M. Topcu, A. Schlessinger, C. Indiveri,
K. Duncan, A. Caglayan, M. Günel, J. Gleeson, G. Novarino, Cell 167 (2016) 1481–1494.
date_created: 2018-12-11T11:50:35Z
date_published: 2016-12-01T00:00:00Z
date_updated: 2024-03-28T23:30:12Z
day: '01'
ddc:
- '576'
- '616'
department:
- _id: GaNo
doi: 10.1016/j.cell.2016.11.013
file:
- access_level: open_access
checksum: 7fe01ab12a6610d3db421e0136db2f77
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:44Z
date_updated: 2020-07-14T12:44:37Z
file_id: '5030'
file_name: IST-2017-771-v1+1_Tarlungeanu_et_al._Final_edited.pdf
file_size: 73907957
relation: main_file
file_date_updated: 2020-07-14T12:44:37Z
has_accepted_license: '1'
intvolume: ' 167'
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 1481 - 1494
project:
- _id: 25473368-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: F03523
name: Transmembrane Transporters in Health and Disease
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '6170'
pubrep_id: '771'
quality_controlled: '1'
related_material:
record:
- id: '395'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Impaired amino acid transport at the blood brain barrier is a cause of autism
spectrum disorder
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 167
year: '2016'
...
---
_id: '1321'
abstract:
- lang: eng
text: Most migrating cells extrude their front by the force of actin polymerization.
Polymerization requires an initial nucleation step, which is mediated by factors
establishing either parallel filaments in the case of filopodia or branched filaments
that form the branched lamellipodial network. Branches are considered essential
for regular cell motility and are initiated by the Arp2/3 complex, which in turn
is activated by nucleation-promoting factors of the WASP and WAVE families. Here
we employed rapid amoeboid crawling leukocytes and found that deletion of the
WAVE complex eliminated actin branching and thus lamellipodia formation. The cells
were left with parallel filaments at the leading edge, which translated, depending
on the differentiation status of the cell, into a unipolar pointed cell shape
or cells with multiple filopodia. Remarkably, unipolar cells migrated with increased
speed and enormous directional persistence, while they were unable to turn towards
chemotactic gradients. Cells with multiple filopodia retained chemotactic activity
but their migration was progressively impaired with increasing geometrical complexity
of the extracellular environment. These findings establish that diversified leading
edge protrusions serve as explorative structures while they slow down actual locomotion.
acknowledged_ssus:
- _id: SSU
acknowledgement: "This work was supported by the German Research Foundation (DFG)
Priority Program SP 1464 to T.E.B.S. and M.S., and European Research Council (ERC
GA 281556) and Human Frontiers Program grants to M.S.\r\nService Units of IST Austria
for excellent technical support."
article_processing_charge: No
article_type: original
author:
- first_name: Alexander F
full_name: Leithner, Alexander F
id: 3B1B77E4-F248-11E8-B48F-1D18A9856A87
last_name: Leithner
orcid: 0000-0002-1073-744X
- first_name: Alexander
full_name: Eichner, Alexander
id: 4DFA52AE-F248-11E8-B48F-1D18A9856A87
last_name: Eichner
- first_name: Jan
full_name: Müller, Jan
id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
last_name: Müller
- first_name: Anne
full_name: Reversat, Anne
id: 35B76592-F248-11E8-B48F-1D18A9856A87
last_name: Reversat
orcid: 0000-0003-0666-8928
- first_name: Markus
full_name: Brown, Markus
id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Jan
full_name: Schwarz, Jan
id: 346C1EC6-F248-11E8-B48F-1D18A9856A87
last_name: Schwarz
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: David
full_name: De Gorter, David
last_name: De Gorter
- first_name: Florian
full_name: Schur, Florian
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Jonathan
full_name: Bayerl, Jonathan
last_name: Bayerl
- first_name: Ingrid
full_name: De Vries, Ingrid
id: 4C7D837E-F248-11E8-B48F-1D18A9856A87
last_name: De Vries
- first_name: Stefan
full_name: Wieser, Stefan
id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
last_name: Wieser
orcid: 0000-0002-2670-2217
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Frank
full_name: Lai, Frank
last_name: Lai
- first_name: Markus
full_name: Moser, Markus
last_name: Moser
- first_name: Dontscho
full_name: Kerjaschki, Dontscho
last_name: Kerjaschki
- first_name: Klemens
full_name: Rottner, Klemens
last_name: Rottner
- first_name: Victor
full_name: Small, Victor
last_name: Small
- first_name: Theresia
full_name: Stradal, Theresia
last_name: Stradal
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Leithner AF, Eichner A, Müller J, et al. Diversified actin protrusions promote
environmental exploration but are dispensable for locomotion of leukocytes. Nature
Cell Biology. 2016;18:1253-1259. doi:10.1038/ncb3426
apa: Leithner, A. F., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz,
J., … Sixt, M. K. (2016). Diversified actin protrusions promote environmental
exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology.
Nature Publishing Group. https://doi.org/10.1038/ncb3426
chicago: Leithner, Alexander F, Alexander Eichner, Jan Müller, Anne Reversat, Markus
Brown, Jan Schwarz, Jack Merrin, et al. “Diversified Actin Protrusions Promote
Environmental Exploration but Are Dispensable for Locomotion of Leukocytes.” Nature
Cell Biology. Nature Publishing Group, 2016. https://doi.org/10.1038/ncb3426.
ieee: A. F. Leithner et al., “Diversified actin protrusions promote environmental
exploration but are dispensable for locomotion of leukocytes,” Nature Cell
Biology, vol. 18. Nature Publishing Group, pp. 1253–1259, 2016.
ista: Leithner AF, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J,
De Gorter D, Schur FK, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai F, Moser
M, Kerjaschki D, Rottner K, Small V, Stradal T, Sixt MK. 2016. Diversified actin
protrusions promote environmental exploration but are dispensable for locomotion
of leukocytes. Nature Cell Biology. 18, 1253–1259.
mla: Leithner, Alexander F., et al. “Diversified Actin Protrusions Promote Environmental
Exploration but Are Dispensable for Locomotion of Leukocytes.” Nature Cell
Biology, vol. 18, Nature Publishing Group, 2016, pp. 1253–59, doi:10.1038/ncb3426.
short: A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz,
J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild,
F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt,
Nature Cell Biology 18 (2016) 1253–1259.
date_created: 2018-12-11T11:51:21Z
date_published: 2016-10-24T00:00:00Z
date_updated: 2024-03-28T23:30:16Z
day: '24'
ddc:
- '570'
department:
- _id: MiSi
- _id: NanoFab
- _id: Bio
doi: 10.1038/ncb3426
ec_funded: 1
file:
- access_level: open_access
checksum: e1411cb7c99a2d9089c178a6abef25e7
content_type: application/pdf
creator: dernst
date_created: 2020-05-14T16:33:46Z
date_updated: 2020-07-14T12:44:43Z
file_id: '7844'
file_name: 2018_NatureCell_Leithner.pdf
file_size: 4433280
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
intvolume: ' 18'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
page: 1253 - 1259
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '281556'
name: Cytoskeletal force generation and force transduction of migrating leukocytes
(EU)
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5949'
quality_controlled: '1'
related_material:
record:
- id: '323'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Diversified actin protrusions promote environmental exploration but are dispensable
for locomotion of leukocytes
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2016'
...
---
_id: '1100'
abstract:
- lang: eng
text: During metazoan development, the temporal pattern of morphogen signaling is
critical for organizing cell fates in space and time. Yet, tools for temporally
controlling morphogen signaling within the embryo are still scarce. Here, we developed
a photoactivatable Nodal receptor to determine how the temporal pattern of Nodal
signaling affects cell fate specification during zebrafish gastrulation. By using
this receptor to manipulate the duration of Nodal signaling in vivo by light,
we show that extended Nodal signaling within the organizer promotes prechordal
plate specification and suppresses endoderm differentiation. Endoderm differentiation
is suppressed by extended Nodal signaling inducing expression of the transcriptional
repressor goosecoid (gsc) in prechordal plate progenitors, which in turn restrains
Nodal signaling from upregulating the endoderm differentiation gene sox17 within
these cells. Thus, optogenetic manipulation of Nodal signaling identifies a critical
role of Nodal signaling duration for organizer cell fate specification during
gastrulation.
acknowledged_ssus:
- _id: SSU
acknowledgement: 'We are grateful to members of the C.-P.H. and H.J. labs for discussions,
R. Hauschild and the different Scientific Service Units at IST Austria for technical
help, M. Dravecka for performing initial experiments, A. Schier for reading an earlier
version of the manuscript, K.W. Rogers for technical help, and C. Hill, A. Bruce,
and L. Solnica-Krezel for sending plasmids. This work was supported by grants from
the Austrian Science Foundation (FWF): (T560-B17) and (I 812-B12) to V.R. and C.-P.H.,
and from the European Union (EU FP7): (6275) to H.J. A.I.-P. is supported by a Ramon
Areces fellowship.'
author:
- first_name: Keisuke
full_name: Sako, Keisuke
id: 3BED66BE-F248-11E8-B48F-1D18A9856A87
last_name: Sako
orcid: 0000-0002-6453-8075
- first_name: Saurabh
full_name: Pradhan, Saurabh
last_name: Pradhan
- first_name: Vanessa
full_name: Barone, Vanessa
id: 419EECCC-F248-11E8-B48F-1D18A9856A87
last_name: Barone
orcid: 0000-0003-2676-3367
- first_name: Álvaro
full_name: Inglés Prieto, Álvaro
id: 2A9DB292-F248-11E8-B48F-1D18A9856A87
last_name: Inglés Prieto
orcid: 0000-0002-5409-8571
- first_name: Patrick
full_name: Mueller, Patrick
last_name: Mueller
- first_name: Verena
full_name: Ruprecht, Verena
id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
last_name: Ruprecht
orcid: 0000-0003-4088-8633
- first_name: Daniel
full_name: Capek, Daniel
id: 31C42484-F248-11E8-B48F-1D18A9856A87
last_name: Capek
orcid: 0000-0001-5199-9940
- first_name: Sanjeev
full_name: Galande, Sanjeev
last_name: Galande
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Sako K, Pradhan S, Barone V, et al. Optogenetic control of nodal signaling
reveals a temporal pattern of nodal signaling regulating cell fate specification
during gastrulation. Cell Reports. 2016;16(3):866-877. doi:10.1016/j.celrep.2016.06.036
apa: Sako, K., Pradhan, S., Barone, V., Inglés Prieto, Á., Mueller, P., Ruprecht,
V., … Heisenberg, C.-P. J. (2016). Optogenetic control of nodal signaling reveals
a temporal pattern of nodal signaling regulating cell fate specification during
gastrulation. Cell Reports. Cell Press. https://doi.org/10.1016/j.celrep.2016.06.036
chicago: Sako, Keisuke, Saurabh Pradhan, Vanessa Barone, Álvaro Inglés Prieto, Patrick
Mueller, Verena Ruprecht, Daniel Capek, Sanjeev Galande, Harald L Janovjak, and
Carl-Philipp J Heisenberg. “Optogenetic Control of Nodal Signaling Reveals a Temporal
Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.”
Cell Reports. Cell Press, 2016. https://doi.org/10.1016/j.celrep.2016.06.036.
ieee: K. Sako et al., “Optogenetic control of nodal signaling reveals a temporal
pattern of nodal signaling regulating cell fate specification during gastrulation,”
Cell Reports, vol. 16, no. 3. Cell Press, pp. 866–877, 2016.
ista: Sako K, Pradhan S, Barone V, Inglés Prieto Á, Mueller P, Ruprecht V, Capek
D, Galande S, Janovjak HL, Heisenberg C-PJ. 2016. Optogenetic control of nodal
signaling reveals a temporal pattern of nodal signaling regulating cell fate specification
during gastrulation. Cell Reports. 16(3), 866–877.
mla: Sako, Keisuke, et al. “Optogenetic Control of Nodal Signaling Reveals a Temporal
Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation.”
Cell Reports, vol. 16, no. 3, Cell Press, 2016, pp. 866–77, doi:10.1016/j.celrep.2016.06.036.
short: K. Sako, S. Pradhan, V. Barone, Á. Inglés Prieto, P. Mueller, V. Ruprecht,
D. Capek, S. Galande, H.L. Janovjak, C.-P.J. Heisenberg, Cell Reports 16 (2016)
866–877.
date_created: 2018-12-11T11:50:08Z
date_published: 2016-07-19T00:00:00Z
date_updated: 2024-03-28T23:30:26Z
day: '19'
ddc:
- '570'
- '576'
department:
- _id: CaHe
- _id: HaJa
doi: 10.1016/j.celrep.2016.06.036
ec_funded: 1
file:
- access_level: open_access
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:04Z
date_updated: 2018-12-12T10:11:04Z
file_id: '4857'
file_name: IST-2017-754-v1+1_1-s2.0-S2211124716307768-main.pdf
file_size: 3921947
relation: main_file
file_date_updated: 2018-12-12T10:11:04Z
has_accepted_license: '1'
intvolume: ' 16'
issue: '3'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 866 - 877
project:
- _id: 2529486C-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: T 560-B17
name: Cell- and Tissue Mechanics in Zebrafish Germ Layer Formation
- _id: 2527D5CC-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I 812-B12
name: Cell Cortex and Germ Layer Formation in Zebrafish Gastrulation
- _id: 25548C20-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303564'
name: Microbial Ion Channels for Synthetic Neurobiology
publication: Cell Reports
publication_status: published
publisher: Cell Press
publist_id: '6275'
pubrep_id: '754'
quality_controlled: '1'
related_material:
record:
- id: '961'
relation: dissertation_contains
status: public
- id: '50'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Optogenetic control of nodal signaling reveals a temporal pattern of nodal
signaling regulating cell fate specification during gastrulation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2016'
...
---
_id: '1437'
abstract:
- lang: eng
text: We study algorithmic questions for concurrent systems where the transitions
are labeled from a complete, closed semiring, and path properties are algebraic
with semiring operations. The algebraic path properties can model dataflow analysis
problems, the shortest path problem, and many other natural problems that arise
in program analysis. We consider that each component of the concurrent system
is a graph with constant treewidth, a property satisfied by the controlflow graphs
of most programs. We allow for multiple possible queries, which arise naturally
in demand driven dataflow analysis. The study of multiple queries allows us to
consider the tradeoff between the resource usage of the one-time preprocessing
and for each individual query. The traditional approach constructs the product
graph of all components and applies the best-known graph algorithm on the product.
In this approach, even the answer to a single query requires the transitive closure
(i.e., the results of all possible queries), which provides no room for tradeoff
between preprocessing and query time. Our main contributions are algorithms that
significantly improve the worst-case running time of the traditional approach,
and provide various tradeoffs depending on the number of queries. For example,
in a concurrent system of two components, the traditional approach requires hexic
time in the worst case for answering one query as well as computing the transitive
closure, whereas we show that with one-time preprocessing in almost cubic time,
each subsequent query can be answered in at most linear time, and even the transitive
closure can be computed in almost quartic time. Furthermore, we establish conditional
optimality results showing that the worst-case running time of our algorithms
cannot be improved without achieving major breakthroughs in graph algorithms (i.e.,
improving the worst-case bound for the shortest path problem in general graphs).
Preliminary experimental results show that our algorithms perform favorably on
several benchmarks.
alternative_title:
- POPL
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Amir
full_name: Goharshady, Amir
id: 391365CE-F248-11E8-B48F-1D18A9856A87
last_name: Goharshady
orcid: 0000-0003-1702-6584
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
citation:
ama: 'Chatterjee K, Goharshady AK, Ibsen-Jensen R, Pavlogiannis A. Algorithms for
algebraic path properties in concurrent systems of constant treewidth components.
In: Vol 20-22. ACM; 2016:733-747. doi:10.1145/2837614.2837624'
apa: 'Chatterjee, K., Goharshady, A. K., Ibsen-Jensen, R., & Pavlogiannis, A.
(2016). Algorithms for algebraic path properties in concurrent systems of constant
treewidth components (Vol. 20–22, pp. 733–747). Presented at the POPL: Principles
of Programming Languages, St. Petersburg, FL, USA: ACM. https://doi.org/10.1145/2837614.2837624'
chicago: Chatterjee, Krishnendu, Amir Kafshdar Goharshady, Rasmus Ibsen-Jensen,
and Andreas Pavlogiannis. “Algorithms for Algebraic Path Properties in Concurrent
Systems of Constant Treewidth Components,” 20–22:733–47. ACM, 2016. https://doi.org/10.1145/2837614.2837624.
ieee: 'K. Chatterjee, A. K. Goharshady, R. Ibsen-Jensen, and A. Pavlogiannis, “Algorithms
for algebraic path properties in concurrent systems of constant treewidth components,”
presented at the POPL: Principles of Programming Languages, St. Petersburg, FL,
USA, 2016, vol. 20–22, pp. 733–747.'
ista: 'Chatterjee K, Goharshady AK, Ibsen-Jensen R, Pavlogiannis A. 2016. Algorithms
for algebraic path properties in concurrent systems of constant treewidth components.
POPL: Principles of Programming Languages, POPL, vol. 20–22, 733–747.'
mla: Chatterjee, Krishnendu, et al. Algorithms for Algebraic Path Properties
in Concurrent Systems of Constant Treewidth Components. Vol. 20–22, ACM, 2016,
pp. 733–47, doi:10.1145/2837614.2837624.
short: K. Chatterjee, A.K. Goharshady, R. Ibsen-Jensen, A. Pavlogiannis, in:, ACM,
2016, pp. 733–747.
conference:
end_date: 2016-01-22
location: St. Petersburg, FL, USA
name: 'POPL: Principles of Programming Languages'
start_date: 2016-01-20
date_created: 2018-12-11T11:52:01Z
date_published: 2016-01-11T00:00:00Z
date_updated: 2024-03-28T23:30:33Z
day: '11'
department:
- _id: KrCh
doi: 10.1145/2837614.2837624
ec_funded: 1
external_id:
arxiv:
- '1510.07565'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1510.07565
month: '01'
oa: 1
oa_version: Preprint
page: 733 - 747
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: ACM
publist_id: '5761'
quality_controlled: '1'
related_material:
record:
- id: '5441'
relation: earlier_version
status: public
- id: '5442'
relation: earlier_version
status: public
- id: '821'
relation: dissertation_contains
status: public
- id: '6009'
relation: later_version
status: public
- id: '8934'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Algorithms for algebraic path properties in concurrent systems of constant
treewidth components
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20-22
year: '2016'
...
---
_id: '1386'
abstract:
- lang: eng
text: We consider nondeterministic probabilistic programs with the most basic liveness
property of termination. We present efficient methods for termination analysis
of nondeterministic probabilistic programs with polynomial guards and assignments.
Our approach is through synthesis of polynomial ranking supermartingales, that
on one hand significantly generalizes linear ranking supermartingales and on the
other hand is a counterpart of polynomial ranking-functions for proving termination
of nonprobabilistic programs. The approach synthesizes polynomial ranking-supermartingales
through Positivstellensatz's, yielding an efficient method which is not only sound,
but also semi-complete over a large subclass of programs. We show experimental
results to demonstrate that our approach can handle several classical programs
with complex polynomial guards and assignments, and can synthesize efficient quadratic
ranking-supermartingales when a linear one does not exist even for simple affine
programs.
alternative_title:
- LNCS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Hongfei
full_name: Fu, Hongfei
id: 3AAD03D6-F248-11E8-B48F-1D18A9856A87
last_name: Fu
- first_name: Amir
full_name: Goharshady, Amir
id: 391365CE-F248-11E8-B48F-1D18A9856A87
last_name: Goharshady
orcid: 0000-0003-1702-6584
citation:
ama: 'Chatterjee K, Fu H, Goharshady AK. Termination analysis of probabilistic programs
through Positivstellensatz’s. In: Vol 9779. Springer; 2016:3-22. doi:10.1007/978-3-319-41528-4_1'
apa: 'Chatterjee, K., Fu, H., & Goharshady, A. K. (2016). Termination analysis
of probabilistic programs through Positivstellensatz’s (Vol. 9779, pp. 3–22).
Presented at the CAV: Computer Aided Verification, Toronto, Canada: Springer.
https://doi.org/10.1007/978-3-319-41528-4_1'
chicago: Chatterjee, Krishnendu, Hongfei Fu, and Amir Kafshdar Goharshady. “Termination
Analysis of Probabilistic Programs through Positivstellensatz’s,” 9779:3–22. Springer,
2016. https://doi.org/10.1007/978-3-319-41528-4_1.
ieee: 'K. Chatterjee, H. Fu, and A. K. Goharshady, “Termination analysis of probabilistic
programs through Positivstellensatz’s,” presented at the CAV: Computer Aided Verification,
Toronto, Canada, 2016, vol. 9779, pp. 3–22.'
ista: 'Chatterjee K, Fu H, Goharshady AK. 2016. Termination analysis of probabilistic
programs through Positivstellensatz’s. CAV: Computer Aided Verification, LNCS,
vol. 9779, 3–22.'
mla: Chatterjee, Krishnendu, et al. Termination Analysis of Probabilistic Programs
through Positivstellensatz’s. Vol. 9779, Springer, 2016, pp. 3–22, doi:10.1007/978-3-319-41528-4_1.
short: K. Chatterjee, H. Fu, A.K. Goharshady, in:, Springer, 2016, pp. 3–22.
conference:
end_date: 2016-07-23
location: Toronto, Canada
name: 'CAV: Computer Aided Verification'
start_date: 2016-07-17
date_created: 2018-12-11T11:51:43Z
date_published: 2016-07-01T00:00:00Z
date_updated: 2024-03-28T23:30:33Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-319-41528-4_1
ec_funded: 1
intvolume: ' 9779'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1604.07169
month: '07'
oa: 1
oa_version: Preprint
page: 3 - 22
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '5824'
quality_controlled: '1'
related_material:
record:
- id: '8934'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Termination analysis of probabilistic programs through Positivstellensatz's
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 9779
year: '2016'
...
---
_id: '10748'
abstract:
- lang: eng
text: The study of fluxoid states and fluxoid dynamics in mesoscopic iron-based
superconducting rings is valuable for characterizing the basic properties of the
superconductor, and may also provide important insight into the superconducting
paring symmetry. We report the fabrications of micron-sized rings and disks from
thin films of Fe(Se, Te) grown by molecular beam epitaxy. In order to study fluxoid
states in rings we developed a custom-tailored version of magnetic force microscopy
(MFM). This technique has a number of qualitative advantages for working with
mesoscopic superconducting samples in comparison to the conventional MFM and other
imaging techniques. We observed metastable fluxoid states in rings of different
sizes. Thermally activated fluxoid dynamics of these states was studied and modeled.
In addition, we found different regimes of interaction between Fe(Se, Te) ring
and MFM tip which are explained. Possibilities of the existence of exotic vortex
states and proposals for experiments to test the symmetry of the superconducting
order parameter in iron based superconductors are analyzed.
alternative_title:
- Bulletin of the American Physical Society
article_number: G16.00009
article_processing_charge: No
author:
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Can
full_name: Zhang, Can
last_name: Zhang
- first_name: Tyler
full_name: Naibert, Tyler
last_name: Naibert
- first_name: James
full_name: Eckstein, James
last_name: Eckstein
- first_name: Raffi
full_name: Budakian, Raffi
last_name: Budakian
citation:
ama: 'Polshyn H, Zhang C, Naibert T, Eckstein J, Budakian R. Study of Fe (Se, Te)
micron-sized rings by magnetic force microscopy. In: APS March Meeting 2015.
Vol 60. American Physical Society; 2015.'
apa: 'Polshyn, H., Zhang, C., Naibert, T., Eckstein, J., & Budakian, R. (2015).
Study of Fe (Se, Te) micron-sized rings by magnetic force microscopy. In APS
March Meeting 2015 (Vol. 60). San Antonio, TX, United States: American Physical
Society.'
chicago: Polshyn, Hryhoriy, Can Zhang, Tyler Naibert, James Eckstein, and Raffi
Budakian. “Study of Fe (Se, Te) Micron-Sized Rings by Magnetic Force Microscopy.”
In APS March Meeting 2015, Vol. 60. American Physical Society, 2015.
ieee: H. Polshyn, C. Zhang, T. Naibert, J. Eckstein, and R. Budakian, “Study of
Fe (Se, Te) micron-sized rings by magnetic force microscopy,” in APS March
Meeting 2015, San Antonio, TX, United States, 2015, vol. 60, no. 1.
ista: 'Polshyn H, Zhang C, Naibert T, Eckstein J, Budakian R. 2015. Study of Fe
(Se, Te) micron-sized rings by magnetic force microscopy. APS March Meeting 2015.
APS: American Physical Society, Bulletin of the American Physical Society, vol.
60, G16.00009.'
mla: Polshyn, Hryhoriy, et al. “Study of Fe (Se, Te) Micron-Sized Rings by Magnetic
Force Microscopy.” APS March Meeting 2015, vol. 60, no. 1, G16.00009, American
Physical Society, 2015.
short: H. Polshyn, C. Zhang, T. Naibert, J. Eckstein, R. Budakian, in:, APS March
Meeting 2015, American Physical Society, 2015.
conference:
end_date: 2015-03-06
location: San Antonio, TX, United States
name: 'APS: American Physical Society'
start_date: 2015-03-02
date_created: 2022-02-08T10:17:09Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2022-02-08T10:42:53Z
day: '01'
extern: '1'
intvolume: ' 60'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://meetings.aps.org/Meeting/MAR15/Event/238442
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2015
publication_identifier:
issn:
- 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Study of Fe (Se, Te) micron-sized rings by magnetic force microscopy
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 60
year: '2015'
...
---
_id: '10794'
abstract:
- lang: eng
text: Mathematical models are of fundamental importance in the understanding of
complex population dynamics. For instance, they can be used to predict the population
evolution starting from different initial conditions or to test how a system responds
to external perturbations. For this analysis to be meaningful in real applications,
however, it is of paramount importance to choose an appropriate model structure
and to infer the model parameters from measured data. While many parameter inference
methods are available for models based on deterministic ordinary differential
equations, the same does not hold for more detailed individual-based models. Here
we consider, in particular, stochastic models in which the time evolution of the
species abundances is described by a continuous-time Markov chain. These models
are governed by a master equation that is typically difficult to solve. Consequently,
traditional inference methods that rely on iterative evaluation of parameter likelihoods
are computationally intractable. The aim of this paper is to present recent advances
in parameter inference for continuous-time Markov chain models, based on a moment
closure approximation of the parameter likelihood, and to investigate how these
results can help in understanding, and ultimately controlling, complex systems
in ecology. Specifically, we illustrate through an agricultural pest case study
how parameters of a stochastic individual-based model can be identified from measured
data and how the resulting model can be used to solve an optimal control problem
in a stochastic setting. In particular, we show how the matter of determining
the optimal combination of two different pest control methods can be formulated
as a chance constrained optimization problem where the control action is modeled
as a state reset, leading to a hybrid system formulation.
acknowledgement: "The authors would like to acknowledge contributions from Baptiste
Mottet who performed preliminary analysis regarding parameter inference for the
considered case study in a student project (Mottet, 2014/2015).\r\nThe research
leading to these results has received funding from the People Programme (Marie Curie
Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under
REA grant agreement No. [291734] and from SystemsX under the project SignalX."
article_number: '42'
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
full_name: Parise, Francesca
last_name: Parise
- first_name: John
full_name: Lygeros, John
last_name: Lygeros
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
citation:
ama: 'Parise F, Lygeros J, Ruess J. Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study. Frontiers in
Environmental Science. 2015;3. doi:10.3389/fenvs.2015.00042'
apa: 'Parise, F., Lygeros, J., & Ruess, J. (2015). Bayesian inference for stochastic
individual-based models of ecological systems: a pest control simulation study.
Frontiers in Environmental Science. Frontiers. https://doi.org/10.3389/fenvs.2015.00042'
chicago: 'Parise, Francesca, John Lygeros, and Jakob Ruess. “Bayesian Inference
for Stochastic Individual-Based Models of Ecological Systems: A Pest Control Simulation
Study.” Frontiers in Environmental Science. Frontiers, 2015. https://doi.org/10.3389/fenvs.2015.00042.'
ieee: 'F. Parise, J. Lygeros, and J. Ruess, “Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study,” Frontiers in
Environmental Science, vol. 3. Frontiers, 2015.'
ista: 'Parise F, Lygeros J, Ruess J. 2015. Bayesian inference for stochastic individual-based
models of ecological systems: a pest control simulation study. Frontiers in Environmental
Science. 3, 42.'
mla: 'Parise, Francesca, et al. “Bayesian Inference for Stochastic Individual-Based
Models of Ecological Systems: A Pest Control Simulation Study.” Frontiers in
Environmental Science, vol. 3, 42, Frontiers, 2015, doi:10.3389/fenvs.2015.00042.'
short: F. Parise, J. Lygeros, J. Ruess, Frontiers in Environmental Science 3 (2015).
date_created: 2022-02-25T11:42:25Z
date_published: 2015-06-10T00:00:00Z
date_updated: 2022-02-25T11:59:23Z
day: '10'
ddc:
- '000'
- '570'
department:
- _id: ToHe
- _id: GaTk
doi: 10.3389/fenvs.2015.00042
ec_funded: 1
file:
- access_level: open_access
checksum: 26c222487564e1be02a11d688d6f769d
content_type: application/pdf
creator: dernst
date_created: 2022-02-25T11:55:26Z
date_updated: 2022-02-25T11:55:26Z
file_id: '10795'
file_name: 2015_FrontiersEnvironmScience_Parise.pdf
file_size: 1371201
relation: main_file
success: 1
file_date_updated: 2022-02-25T11:55:26Z
has_accepted_license: '1'
intvolume: ' 3'
keyword:
- General Environmental Science
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Frontiers in Environmental Science
publication_identifier:
issn:
- 2296-665X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bayesian inference for stochastic individual-based models of ecological systems:
a pest control simulation study'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2015'
...
---
_id: '11079'
abstract:
- lang: eng
text: Aging is a major risk factor for many human diseases, and in vitro generation
of human neurons is an attractive approach for modeling aging-related brain disorders.
However, modeling aging in differentiated human neurons has proved challenging.
We generated neurons from human donors across a broad range of ages, either by
iPSC-based reprogramming and differentiation or by direct conversion into induced
neurons (iNs). While iPSCs and derived neurons did not retain aging-associated
gene signatures, iNs displayed age-specific transcriptional profiles and revealed
age-associated decreases in the nuclear transport receptor RanBP17. We detected
an age-dependent loss of nucleocytoplasmic compartmentalization (NCC) in donor
fibroblasts and corresponding iNs and found that reduced RanBP17 impaired NCC
in young cells, while iPSC rejuvenation restored NCC in aged cells. These results
show that iNs retain important aging-related signatures, thus allowing modeling
of the aging process in vitro, and they identify impaired NCC as an important
factor in human aging.
article_processing_charge: No
article_type: original
author:
- first_name: Jerome
full_name: Mertens, Jerome
last_name: Mertens
- first_name: Apuã C.M.
full_name: Paquola, Apuã C.M.
last_name: Paquola
- first_name: Manching
full_name: Ku, Manching
last_name: Ku
- first_name: Emily
full_name: Hatch, Emily
last_name: Hatch
- first_name: Lena
full_name: Böhnke, Lena
last_name: Böhnke
- first_name: Shauheen
full_name: Ladjevardi, Shauheen
last_name: Ladjevardi
- first_name: Sean
full_name: McGrath, Sean
last_name: McGrath
- first_name: Benjamin
full_name: Campbell, Benjamin
last_name: Campbell
- first_name: Hyungjun
full_name: Lee, Hyungjun
last_name: Lee
- first_name: Joseph R.
full_name: Herdy, Joseph R.
last_name: Herdy
- first_name: J. Tiago
full_name: Gonçalves, J. Tiago
last_name: Gonçalves
- first_name: Tomohisa
full_name: Toda, Tomohisa
last_name: Toda
- first_name: Yongsung
full_name: Kim, Yongsung
last_name: Kim
- first_name: Jürgen
full_name: Winkler, Jürgen
last_name: Winkler
- first_name: Jun
full_name: Yao, Jun
last_name: Yao
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Fred H.
full_name: Gage, Fred H.
last_name: Gage
citation:
ama: Mertens J, Paquola ACM, Ku M, et al. Directly reprogrammed human neurons retain
aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic
defects. Cell Stem Cell. 2015;17(6):705-718. doi:10.1016/j.stem.2015.09.001
apa: Mertens, J., Paquola, A. C. M., Ku, M., Hatch, E., Böhnke, L., Ladjevardi,
S., … Gage, F. H. (2015). Directly reprogrammed human neurons retain aging-associated
transcriptomic signatures and reveal age-related nucleocytoplasmic defects. Cell
Stem Cell. Elsevier. https://doi.org/10.1016/j.stem.2015.09.001
chicago: Mertens, Jerome, Apuã C.M. Paquola, Manching Ku, Emily Hatch, Lena Böhnke,
Shauheen Ladjevardi, Sean McGrath, et al. “Directly Reprogrammed Human Neurons
Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic
Defects.” Cell Stem Cell. Elsevier, 2015. https://doi.org/10.1016/j.stem.2015.09.001.
ieee: J. Mertens et al., “Directly reprogrammed human neurons retain aging-associated
transcriptomic signatures and reveal age-related nucleocytoplasmic defects,” Cell
Stem Cell, vol. 17, no. 6. Elsevier, pp. 705–718, 2015.
ista: Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S,
Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer
M, Gage FH. 2015. Directly reprogrammed human neurons retain aging-associated
transcriptomic signatures and reveal age-related nucleocytoplasmic defects. Cell
Stem Cell. 17(6), 705–718.
mla: Mertens, Jerome, et al. “Directly Reprogrammed Human Neurons Retain Aging-Associated
Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.” Cell
Stem Cell, vol. 17, no. 6, Elsevier, 2015, pp. 705–18, doi:10.1016/j.stem.2015.09.001.
short: J. Mertens, A.C.M. Paquola, M. Ku, E. Hatch, L. Böhnke, S. Ladjevardi, S.
McGrath, B. Campbell, H. Lee, J.R. Herdy, J.T. Gonçalves, T. Toda, Y. Kim, J.
Winkler, J. Yao, M. Hetzer, F.H. Gage, Cell Stem Cell 17 (2015) 705–718.
date_created: 2022-04-07T07:49:51Z
date_published: 2015-12-03T00:00:00Z
date_updated: 2022-07-18T08:44:21Z
day: '03'
doi: 10.1016/j.stem.2015.09.001
extern: '1'
external_id:
pmid:
- '26456686'
intvolume: ' 17'
issue: '6'
keyword:
- Cell Biology
- Genetics
- Molecular Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.stem.2015.09.001
month: '12'
oa: 1
oa_version: Published Version
page: 705-718
pmid: 1
publication: Cell Stem Cell
publication_identifier:
issn:
- 1934-5909
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Directly reprogrammed human neurons retain aging-associated transcriptomic
signatures and reveal age-related nucleocytoplasmic defects
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 17
year: '2015'
...
---
_id: '11077'
abstract:
- lang: eng
text: Nucleoporins (Nups) are a family of proteins best known as the constituent
building blocks of nuclear pore complexes (NPCs), membrane-embedded channels that
mediate nuclear transport across the nuclear envelope. Recent evidence suggests
that several Nups have additional roles in controlling the activation and silencing
of developmental genes; however, the mechanistic details of these functions remain
poorly understood. Here, we show that depletion of Nup153 in mouse embryonic stem
cells (mESCs) causes the derepression of developmental genes and induction of
early differentiation. This loss of stem cell identity is not associated with
defects in the nuclear import of key pluripotency factors. Rather, Nup153 binds
around the transcriptional start site (TSS) of developmental genes and mediates
the recruitment of the polycomb-repressive complex 1 (PRC1) to a subset of its
target loci. Our results demonstrate a chromatin-associated role of Nup153 in
maintaining stem cell pluripotency by functioning in mammalian epigenetic gene
silencing.
article_processing_charge: No
article_type: original
author:
- first_name: Filipe V.
full_name: Jacinto, Filipe V.
last_name: Jacinto
- first_name: Chris
full_name: Benner, Chris
last_name: Benner
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Jacinto FV, Benner C, Hetzer M. The nucleoporin Nup153 regulates embryonic
stem cell pluripotency through gene silencing. Genes & Development.
2015;29(12):1224-1238. doi:10.1101/gad.260919.115
apa: Jacinto, F. V., Benner, C., & Hetzer, M. (2015). The nucleoporin Nup153
regulates embryonic stem cell pluripotency through gene silencing. Genes &
Development. Cold Spring Harbor Laboratory. https://doi.org/10.1101/gad.260919.115
chicago: Jacinto, Filipe V., Chris Benner, and Martin Hetzer. “The Nucleoporin Nup153
Regulates Embryonic Stem Cell Pluripotency through Gene Silencing.” Genes &
Development. Cold Spring Harbor Laboratory, 2015. https://doi.org/10.1101/gad.260919.115.
ieee: F. V. Jacinto, C. Benner, and M. Hetzer, “The nucleoporin Nup153 regulates
embryonic stem cell pluripotency through gene silencing,” Genes & Development,
vol. 29, no. 12. Cold Spring Harbor Laboratory, pp. 1224–1238, 2015.
ista: Jacinto FV, Benner C, Hetzer M. 2015. The nucleoporin Nup153 regulates embryonic
stem cell pluripotency through gene silencing. Genes & Development. 29(12),
1224–1238.
mla: Jacinto, Filipe V., et al. “The Nucleoporin Nup153 Regulates Embryonic Stem
Cell Pluripotency through Gene Silencing.” Genes & Development, vol.
29, no. 12, Cold Spring Harbor Laboratory, 2015, pp. 1224–38, doi:10.1101/gad.260919.115.
short: F.V. Jacinto, C. Benner, M. Hetzer, Genes & Development 29 (2015) 1224–1238.
date_created: 2022-04-07T07:49:31Z
date_published: 2015-06-16T00:00:00Z
date_updated: 2022-07-18T08:43:51Z
day: '16'
doi: 10.1101/gad.260919.115
extern: '1'
external_id:
pmid:
- '26080816'
intvolume: ' 29'
issue: '12'
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/gad.260919.115
month: '06'
oa: 1
oa_version: Published Version
page: 1224-1238
pmid: 1
publication: Genes & Development
publication_identifier:
eissn:
- 1549-5477
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene
silencing
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 29
year: '2015'
...
---
_id: '11078'
abstract:
- lang: eng
text: Aging is associated with the decline of protein, cell, and organ function.
Here, we use an integrated approach to characterize gene expression, bulk translation,
and cell biology in the brains and livers of young and old rats. We identify 468
differences in protein abundance between young and old animals. The majority are
a consequence of altered translation output, that is, the combined effect of changes
in transcript abundance and translation efficiency. In addition, we identify 130
proteins whose overall abundance remains unchanged but whose sub-cellular localization,
phosphorylation state, or splice-form varies. While some protein-level differences
appear to be a generic property of the rats’ chronological age, the majority are
specific to one organ. These may be a consequence of the organ’s physiology or
the chronological age of the cells within the tissue. Taken together, our study
provides an initial view of the proteome at the molecular, sub-cellular, and organ
level in young and old rats.
article_processing_charge: No
article_type: original
author:
- first_name: Alessandro
full_name: Ori, Alessandro
last_name: Ori
- first_name: Brandon H.
full_name: Toyama, Brandon H.
last_name: Toyama
- first_name: Michael S.
full_name: Harris, Michael S.
last_name: Harris
- first_name: Thomas
full_name: Bock, Thomas
last_name: Bock
- first_name: Murat
full_name: Iskar, Murat
last_name: Iskar
- first_name: Peer
full_name: Bork, Peer
last_name: Bork
- first_name: Nicholas T.
full_name: Ingolia, Nicholas T.
last_name: Ingolia
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Martin
full_name: Beck, Martin
last_name: Beck
citation:
ama: Ori A, Toyama BH, Harris MS, et al. Integrated transcriptome and proteome analyses
reveal organ-specific proteome deterioration in old rats. Cell Systems.
2015;1(3):P224-237. doi:10.1016/j.cels.2015.08.012
apa: Ori, A., Toyama, B. H., Harris, M. S., Bock, T., Iskar, M., Bork, P., … Beck,
M. (2015). Integrated transcriptome and proteome analyses reveal organ-specific
proteome deterioration in old rats. Cell Systems. Elsevier. https://doi.org/10.1016/j.cels.2015.08.012
chicago: Ori, Alessandro, Brandon H. Toyama, Michael S. Harris, Thomas Bock, Murat
Iskar, Peer Bork, Nicholas T. Ingolia, Martin Hetzer, and Martin Beck. “Integrated
Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration
in Old Rats.” Cell Systems. Elsevier, 2015. https://doi.org/10.1016/j.cels.2015.08.012.
ieee: A. Ori et al., “Integrated transcriptome and proteome analyses reveal
organ-specific proteome deterioration in old rats,” Cell Systems, vol.
1, no. 3. Elsevier, pp. P224-237, 2015.
ista: Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer M,
Beck M. 2015. Integrated transcriptome and proteome analyses reveal organ-specific
proteome deterioration in old rats. Cell Systems. 1(3), P224-237.
mla: Ori, Alessandro, et al. “Integrated Transcriptome and Proteome Analyses Reveal
Organ-Specific Proteome Deterioration in Old Rats.” Cell Systems, vol.
1, no. 3, Elsevier, 2015, pp. P224-237, doi:10.1016/j.cels.2015.08.012.
short: A. Ori, B.H. Toyama, M.S. Harris, T. Bock, M. Iskar, P. Bork, N.T. Ingolia,
M. Hetzer, M. Beck, Cell Systems 1 (2015) P224-237.
date_created: 2022-04-07T07:49:39Z
date_published: 2015-09-23T00:00:00Z
date_updated: 2022-07-18T08:44:07Z
day: '23'
doi: 10.1016/j.cels.2015.08.012
extern: '1'
external_id:
pmid:
- '27135913'
intvolume: ' 1'
issue: '3'
keyword:
- Cell Biology
- Histology
- Pathology and Forensic Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cels.2015.08.012
month: '09'
oa: 1
oa_version: Published Version
page: P224-237
pmid: 1
publication: Cell Systems
publication_identifier:
issn:
- 2405-4712
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Integrated transcriptome and proteome analyses reveal organ-specific proteome
deterioration in old rats
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 1
year: '2015'
...
---
_id: '11076'
abstract:
- lang: eng
text: Nuclear pore complexes (NPCs) are composed of several copies of ∼30 different
proteins called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE)
and regulate the nucleocytoplasmic trafficking of macromolecules. Beyond this
vital role, NPC components influence genome functions in a transport-independent
manner. Nups play an evolutionarily conserved role in gene expression regulation
that, in metazoans, extends into the nuclear interior. Additionally, in proliferative
cells, Nups play a crucial role in genome integrity maintenance and mitotic progression.
Here we discuss genome-related functions of Nups and their impact on essential
DNA metabolism processes such as transcription, chromosome duplication, and segregation.
article_processing_charge: No
article_type: original
author:
- first_name: Arkaitz
full_name: Ibarra, Arkaitz
last_name: Ibarra
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Ibarra A, Hetzer M. Nuclear pore proteins and the control of genome functions.
Genes & Development. 2015;29(4):337-349. doi:10.1101/gad.256495.114
apa: Ibarra, A., & Hetzer, M. (2015). Nuclear pore proteins and the control
of genome functions. Genes & Development. Cold Spring Harbor Laboratory.
https://doi.org/10.1101/gad.256495.114
chicago: Ibarra, Arkaitz, and Martin Hetzer. “Nuclear Pore Proteins and the Control
of Genome Functions.” Genes & Development. Cold Spring Harbor Laboratory,
2015. https://doi.org/10.1101/gad.256495.114.
ieee: A. Ibarra and M. Hetzer, “Nuclear pore proteins and the control of genome
functions,” Genes & Development, vol. 29, no. 4. Cold Spring Harbor
Laboratory, pp. 337–349, 2015.
ista: Ibarra A, Hetzer M. 2015. Nuclear pore proteins and the control of genome
functions. Genes & Development. 29(4), 337–349.
mla: Ibarra, Arkaitz, and Martin Hetzer. “Nuclear Pore Proteins and the Control
of Genome Functions.” Genes & Development, vol. 29, no. 4, Cold Spring
Harbor Laboratory, 2015, pp. 337–49, doi:10.1101/gad.256495.114.
short: A. Ibarra, M. Hetzer, Genes & Development 29 (2015) 337–349.
date_created: 2022-04-07T07:49:21Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2022-07-18T08:43:20Z
day: '01'
doi: 10.1101/gad.256495.114
extern: '1'
external_id:
pmid:
- '25691464'
intvolume: ' 29'
issue: '4'
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/gad.256495.114
month: '02'
oa: 1
oa_version: Published Version
page: 337-349
pmid: 1
publication: Genes & Development
publication_identifier:
eissn:
- 1549-5477
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nuclear pore proteins and the control of genome functions
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 29
year: '2015'
...
---
_id: '11073'
abstract:
- lang: eng
text: Human cancer cells bear complex chromosome rearrangements that can be potential
drivers of cancer development. However, the molecular mechanisms underlying these
rearrangements have been unclear. Zhang et al. use a new technique combining live-cell
imaging and single-cell sequencing to demonstrate that chromosomes mis-segregated
to micronuclei frequently undergo chromothripsis-like rearrangements in the subsequent
cell cycle.
article_processing_charge: No
article_type: original
author:
- first_name: Emily M.
full_name: Hatch, Emily M.
last_name: Hatch
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Hatch EM, Hetzer M. Linking micronuclei to chromosome fragmentation. Cell.
2015;161(7):1502-1504. doi:10.1016/j.cell.2015.06.005
apa: Hatch, E. M., & Hetzer, M. (2015). Linking micronuclei to chromosome fragmentation.
Cell. Elsevier. https://doi.org/10.1016/j.cell.2015.06.005
chicago: Hatch, Emily M., and Martin Hetzer. “Linking Micronuclei to Chromosome
Fragmentation.” Cell. Elsevier, 2015. https://doi.org/10.1016/j.cell.2015.06.005.
ieee: E. M. Hatch and M. Hetzer, “Linking micronuclei to chromosome fragmentation,”
Cell, vol. 161, no. 7. Elsevier, pp. 1502–1504, 2015.
ista: Hatch EM, Hetzer M. 2015. Linking micronuclei to chromosome fragmentation.
Cell. 161(7), 1502–1504.
mla: Hatch, Emily M., and Martin Hetzer. “Linking Micronuclei to Chromosome Fragmentation.”
Cell, vol. 161, no. 7, Elsevier, 2015, pp. 1502–04, doi:10.1016/j.cell.2015.06.005.
short: E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.
date_created: 2022-04-07T07:48:49Z
date_published: 2015-06-18T00:00:00Z
date_updated: 2022-07-18T08:34:33Z
day: '18'
doi: 10.1016/j.cell.2015.06.005
extern: '1'
external_id:
pmid:
- '26091034'
intvolume: ' 161'
issue: '7'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2015.06.005
month: '06'
oa: 1
oa_version: Published Version
page: 1502-1504
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Linking micronuclei to chromosome fragmentation
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 161
year: '2015'
...
---
_id: '11074'
article_processing_charge: No
article_type: original
author:
- first_name: Emily M.
full_name: Hatch, Emily M.
last_name: Hatch
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
citation:
ama: Hatch EM, Hetzer M. Chromothripsis. Current Biology. 2015;25(10):PR397-R399.
doi:10.1016/j.cub.2015.02.033
apa: Hatch, E. M., & Hetzer, M. (2015). Chromothripsis. Current Biology.
Elsevier. https://doi.org/10.1016/j.cub.2015.02.033
chicago: Hatch, Emily M., and Martin Hetzer. “Chromothripsis.” Current Biology.
Elsevier, 2015. https://doi.org/10.1016/j.cub.2015.02.033.
ieee: E. M. Hatch and M. Hetzer, “Chromothripsis,” Current Biology, vol.
25, no. 10. Elsevier, pp. PR397-R399, 2015.
ista: Hatch EM, Hetzer M. 2015. Chromothripsis. Current Biology. 25(10), PR397-R399.
mla: Hatch, Emily M., and Martin Hetzer. “Chromothripsis.” Current Biology,
vol. 25, no. 10, Elsevier, 2015, pp. PR397-R399, doi:10.1016/j.cub.2015.02.033.
short: E.M. Hatch, M. Hetzer, Current Biology 25 (2015) PR397-R399.
date_created: 2022-04-07T07:49:00Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2022-07-18T08:34:34Z
day: '18'
doi: 10.1016/j.cub.2015.02.033
extern: '1'
external_id:
pmid:
- '25989073'
intvolume: ' 25'
issue: '10'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cub.2015.02.033
month: '05'
oa: 1
oa_version: Published Version
page: PR397-R399
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromothripsis
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 25
year: '2015'
...
---
_id: '11519'
abstract:
- lang: eng
text: 'Faint Lyα emitters become increasingly rarer toward the reionization epoch
(z ∼ 6–7). However, observations from a very large (∼5 deg2) Lyα narrow-band survey
at z = 6.6 show that this is not the case for the most luminous emitters, capable
of ionizing their own local bubbles. Here we present follow-up observations of
the two most luminous Lyα candidates in the COSMOS field: “MASOSA” and “CR7.”
We used X-SHOOTER, SINFONI, and FORS2 on the Very Large Telescope, and DEIMOS
on Keck, to confirm both candidates beyond any doubt. We find redshifts of z =
6.541 and z = 6.604 for “MASOSA” and “CR7,” respectively. MASOSA has a strong
detection in Lyα with a line width of 386 ± 30 km s−1 (FWHM) and with very high
EW0 (>200 Å), but undetected in the continuum, implying very low stellar mass
and a likely young, metal-poor stellar population. “CR7,” with an observed Lyα
luminosity of 1043.92±0.05 erg s−1 is the most luminous Lyα emitter ever found
at z > 6 and is spatially extended (∼16 kpc). “CR7” reveals a narrow Lyα line
with 266 ± 15 km s−1 FWHM, being detected in the near-infrared (NIR) (rest-frame
UV; β = −2.3 ± 0.1) and in IRAC/Spitzer. We detect a narrow He II 1640 Å emission
line (6σ, FWHM = 130 ± 30 km s−1 ) in CR7 which can explain the clear excess seen
in the J-band photometry (EW0 ∼ 80 Å). We find no other emission lines from the
UV to the NIR in our X-SHOOTER spectra (He II/O III] 1663 Å > 3 and He II/C III]
1908 Å > 2.5). We conclude that CR7 is best explained by a combination of a PopIII-like
population, which dominates the rest-frame UV and the nebular emission, and a
more normal stellar population, which presumably dominates the mass. Hubble Space
Telescope/WFC3 observations show that the light is indeed spatially separated
between a very blue component, coincident with Lyα and He II emission, and two
red components (∼5 kpc away), which dominate the mass. Our findings are consistent
with theoretical predictions of a PopIII wave, with PopIII star formation migrating
away from the original sites of star formation.'
acknowledgement: We thank the anonymous reviewer for useful and constructive comments
and suggestions which greatly improved the quality and clarity of our work. D.S.
acknowledges financial support from the Netherlands Organisation for Scientific
research (NWO) through a Veni fellowship, from FCT through a FCT Investigator Starting
Grant and Start-up Grant (IF/01154/2012/CP0189/CT0010), from FCT grant UID/FIS/04434/2013,
and from LSF and LKBF. J.M. acknowledges the award of a Huygens PhD fellowship.
H.R. acknowledges support from the ERC Advanced Investigator program NewClusters
321271. The authors thank Mark Dijkstra, Bhaskar Agarwal, Jarrett Johnson, Andrea
Ferrara, Jarle Brinchmann, Rebecca Bowler, George Becker, Emma Curtis-Lake, Milos
Milosavljevic, Raffaella Schneider, Paul Shapiro, and Erik Zackrisson for interesting,
stimulating and helpful discussions. The authors are extremely grateful to ESO for
the award of ESO DDT time (294.A-5018 and 294.A-5039) which allowed the spectroscopic
confirmation of both sources and the detailed investigation of their nature. Observations
are also based on data from W.M. Keck Observatory. The W.M. Keck Observatory is
operated as a scientific partnership of Caltech, the University of California and
the National Aeronautics and Space Administration. Based on observations obtained
with MegaPrime/Megacam, a joint project of CFHT and CEA/IRFU, at the Canada–France–Hawaii
Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada,
the Institut National des Science de lUnivers of the Centre National de la Recherche
Scientifique (CNRS) of France, and the University of Hawaii. This work is based
in part on data products produced at Terapix available at the Canadian Astronomy
Data Centre as part of the Canada–France–Hawaii Telescope Legacy Survey, a collaborative
project of NRC and CNRS. Based on data products from observations made with ESO
Telescopes at the La Silla Paranal Observatory under ESO programme IDs 294.A-5018,
294.A-5039, and 179.A-2005, and on data products produced by TERAPIX and the Cambridge
Astronomy Survey Unit on behalf of the UltraVISTA consortium. The authors acknowledge
the award of service time (SW2014b20) on the William Herschel Telescope (WHT). WHT
and its service programme are operated on the island of La Palma by the Isaac Newton
Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de
Astrofisica de Canarias.
article_processing_charge: No
article_type: original
author:
- first_name: David
full_name: Sobral, David
last_name: Sobral
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Behnam
full_name: Darvish, Behnam
last_name: Darvish
- first_name: Daniel
full_name: Schaerer, Daniel
last_name: Schaerer
- first_name: Bahram
full_name: Mobasher, Bahram
last_name: Mobasher
- first_name: Huub
full_name: Röttgering, Huub
last_name: Röttgering
- first_name: Sérgio
full_name: Santos, Sérgio
last_name: Santos
- first_name: Shoubaneh
full_name: Hemmati, Shoubaneh
last_name: Hemmati
citation:
ama: 'Sobral D, Matthee JJ, Darvish B, et al. Evidence for PopIII-like stellar populations
in the most luminous Lyα emitters at the epoch of reionisation: Spectroscopic
confirmation. The Astrophysical Journal. 2015;808(2):139. doi:10.1088/0004-637X/808/2/139'
apa: 'Sobral, D., Matthee, J. J., Darvish, B., Schaerer, D., Mobasher, B., Röttgering,
H., … Hemmati, S. (2015). Evidence for PopIII-like stellar populations in the
most luminous Lyα emitters at the epoch of reionisation: Spectroscopic confirmation.
The Astrophysical Journal. IOP Publishing. https://doi.org/10.1088/0004-637X/808/2/139'
chicago: 'Sobral, David, Jorryt J Matthee, Behnam Darvish, Daniel Schaerer, Bahram
Mobasher, Huub Röttgering, Sérgio Santos, and Shoubaneh Hemmati. “Evidence for
PopIII-like Stellar Populations in the Most Luminous Lyα Emitters at the Epoch
of Reionisation: Spectroscopic Confirmation.” The Astrophysical Journal.
IOP Publishing, 2015. https://doi.org/10.1088/0004-637X/808/2/139.'
ieee: 'D. Sobral et al., “Evidence for PopIII-like stellar populations in
the most luminous Lyα emitters at the epoch of reionisation: Spectroscopic confirmation,”
The Astrophysical Journal, vol. 808, no. 2. IOP Publishing, p. 139, 2015.'
ista: 'Sobral D, Matthee JJ, Darvish B, Schaerer D, Mobasher B, Röttgering H, Santos
S, Hemmati S. 2015. Evidence for PopIII-like stellar populations in the most luminous
Lyα emitters at the epoch of reionisation: Spectroscopic confirmation. The Astrophysical
Journal. 808(2), 139.'
mla: 'Sobral, David, et al. “Evidence for PopIII-like Stellar Populations in the
Most Luminous Lyα Emitters at the Epoch of Reionisation: Spectroscopic Confirmation.”
The Astrophysical Journal, vol. 808, no. 2, IOP Publishing, 2015, p. 139,
doi:10.1088/0004-637X/808/2/139.'
short: D. Sobral, J.J. Matthee, B. Darvish, D. Schaerer, B. Mobasher, H. Röttgering,
S. Santos, S. Hemmati, The Astrophysical Journal 808 (2015) 139.
date_created: 2022-07-07T09:00:58Z
date_published: 2015-07-28T00:00:00Z
date_updated: 2022-08-18T10:30:13Z
day: '28'
doi: 10.1088/0004-637X/808/2/139
extern: '1'
external_id:
arxiv:
- '1504.01734'
intvolume: ' 808'
issue: '2'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- dark ages
- reionization
- 'first stars – early universe – galaxies: evolution'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1504.01734
month: '07'
oa: 1
oa_version: Preprint
page: '139'
publication: The Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Evidence for PopIII-like stellar populations in the most luminous Lyα emitters
at the epoch of reionisation: Spectroscopic confirmation'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 808
year: '2015'
...
---
_id: '11580'
abstract:
- lang: eng
text: 'We present results from the largest contiguous narrow-band survey in the
near-infrared. We have used the wide-field infrared camera/Canada–France–Hawaii
Telescope and the lowOH2 filter (1.187 ± 0.005 μm) to survey ≈10 deg2 of contiguous
extragalactic sky in the SA22 field. A total of ∼6000 candidate emission-line
galaxies are found. We use deep ugrizJK data to obtain robust photometric redshifts.
We combine our data with the High-redshift(Z) Emission Line Survey (HiZELS), explore
spectroscopic surveys (VVDS, VIPERS) and obtain our own spectroscopic follow-up
with KMOS, FMOS and MOSFIRE to derive large samples of high-redshift emission-line
selected galaxies: 3471 Hα emitters at z = 0.8, 1343 [O III] + Hβ emitters at
z = 1.4 and 572 [O II] emitters at z = 2.2. We probe comoving volumes of >106
Mpc3 and find significant overdensities, including an 8.5σ (spectroscopically
confirmed) overdensity of Hα emitters at z = 0.81. We derive Hα, [O III] + Hβ
and [O II] luminosity functions at z = 0.8, 1.4, 2.2, respectively, and present
implications for future surveys such as Euclid. Our uniquely large volumes/areas
allow us to subdivide the samples in thousands of randomized combinations of areas
and provide a robust empirical measurement of sample/cosmic variance. We show
that surveys for star-forming/emission-line galaxies at a depth similar to ours
can only overcome cosmic-variance (errors <10 per cent) if they are based on volumes
>5 × 105 Mpc3; errors on L* and ϕ* due to sample (cosmic) variance on surveys
probing ∼104 and ∼105 Mpc3 are typically very high: ∼300 and ∼40–60 per cent,
respectively.'
acknowledgement: The authors wish to thank the anonymous reviewer for many helpful
comments and suggestions which greatly improved the clarity and quality of this
work. DS acknowledges financial support from the Netherlands Organization for Scientific
research (NWO) through a Veni fellowship, from FCT through an FCT Investigator Starting
Grant and Start-up Grant (IF/01154/2012/CP0189/CT0010), from FCT grant PEst-OE/FIS/UI2751/2014,
and from LSF and LKBF. JM acknowledges the award of a Huygens PhD fellowship. PNB
is grateful for support from STFC. IRS acknowledges support from STFC, a Leverhulme
Fellowship, the ERC Advanced Investigator programme DUSTYGAL and a Royal Society/Wolfson
Merit Award. BMJ acknowledges support from the ERC-StG grant EGGS-278202. The Dark
Cosmology Centre is funded by the DNRF. The Dark Cosmology Centre is funded by the
DNRF. JWK acknowledges support from the National Research Foundation of Korea (NRF)
grant, no. 2008-0060544, funded by the Korea government (MSIP). JPS acknowledges
support from STFC (ST/I001573/1). JC acknowledges support from the FCT-IF grant
IF/01154/2012/CP0189/CT0010. The work was only possible due to OPTICON/FP7 and the
invaluable access that it granted to the CFHT telescope. We would also like to acknowledge
the excellent work done by CFHT staff in conducting the observations in service
mode, and on delivering truly excellent data. We are also tremendously thankful
to Kentaro Aoki for the incredible support while observing at Subaru with FMOS,
and also to the Keck staff for the help with the observations with MOSFIRE. This
work is based on observations obtained with WIRCam on the CFHT, OPTICON programme
2011B/029, 2012A019 and 2012B/016. Based on observations made with ESO telescopes
at the La Silla Paranal Observatory under programmes IDs 60.A-9460 (data can be
accessed through the ESO data archive), 087.A 0337 and 089.A-0965. Based on observations
done with FMOS on Subaru under programme S14A-084, and on MOSFIRE/Keck observations
under programme U066M. Part of the data on which this analysis is based are available
from Sobral et al. (2013a). Dedicated to the memory of C. M. Sobral (1953-2014).
article_processing_charge: No
article_type: original
author:
- first_name: D.
full_name: Sobral, D.
last_name: Sobral
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: P. N.
full_name: Best, P. N.
last_name: Best
- first_name: I.
full_name: Smail, I.
last_name: Smail
- first_name: A. A.
full_name: Khostovan, A. A.
last_name: Khostovan
- first_name: B.
full_name: Milvang-Jensen, B.
last_name: Milvang-Jensen
- first_name: J.-W.
full_name: Kim, J.-W.
last_name: Kim
- first_name: J.
full_name: Stott, J.
last_name: Stott
- first_name: J.
full_name: Calhau, J.
last_name: Calhau
- first_name: H.
full_name: Nayyeri, H.
last_name: Nayyeri
- first_name: B.
full_name: Mobasher, B.
last_name: Mobasher
citation:
ama: 'Sobral D, Matthee JJ, Best PN, et al. CF-HiZELS, an ∼10 deg2 emission-line
survey with spectroscopic follow-up: Hα, [O III] + Hβ and [O II] luminosity functions
at z = 0.8, 1.4 and 2.2 . Monthly Notices of the Royal Astronomical Society.
2015;451(3):2303-2323. doi:10.1093/mnras/stv1076'
apa: 'Sobral, D., Matthee, J. J., Best, P. N., Smail, I., Khostovan, A. A., Milvang-Jensen,
B., … Mobasher, B. (2015). CF-HiZELS, an ∼10 deg2 emission-line survey with spectroscopic
follow-up: Hα, [O III] + Hβ and [O II] luminosity functions at z = 0.8, 1.4 and
2.2 . Monthly Notices of the Royal Astronomical Society. Oxford University
Press. https://doi.org/10.1093/mnras/stv1076'
chicago: 'Sobral, D., Jorryt J Matthee, P. N. Best, I. Smail, A. A. Khostovan, B.
Milvang-Jensen, J.-W. Kim, et al. “CF-HiZELS, an ∼10 Deg2 Emission-Line Survey
with Spectroscopic Follow-up: Hα, [O III] + Hβ and [O II] Luminosity Functions
at z = 0.8, 1.4 and 2.2 .” Monthly Notices of the Royal Astronomical Society.
Oxford University Press, 2015. https://doi.org/10.1093/mnras/stv1076.'
ieee: 'D. Sobral et al., “CF-HiZELS, an ∼10 deg2 emission-line survey with
spectroscopic follow-up: Hα, [O III] + Hβ and [O II] luminosity functions at z
= 0.8, 1.4 and 2.2 ,” Monthly Notices of the Royal Astronomical Society,
vol. 451, no. 3. Oxford University Press, pp. 2303–2323, 2015.'
ista: 'Sobral D, Matthee JJ, Best PN, Smail I, Khostovan AA, Milvang-Jensen B, Kim
J-W, Stott J, Calhau J, Nayyeri H, Mobasher B. 2015. CF-HiZELS, an ∼10 deg2 emission-line
survey with spectroscopic follow-up: Hα, [O III] + Hβ and [O II] luminosity functions
at z = 0.8, 1.4 and 2.2 . Monthly Notices of the Royal Astronomical Society. 451(3),
2303–2323.'
mla: 'Sobral, D., et al. “CF-HiZELS, an ∼10 Deg2 Emission-Line Survey with Spectroscopic
Follow-up: Hα, [O III] + Hβ and [O II] Luminosity Functions at z = 0.8, 1.4 and
2.2 .” Monthly Notices of the Royal Astronomical Society, vol. 451, no.
3, Oxford University Press, 2015, pp. 2303–23, doi:10.1093/mnras/stv1076.'
short: D. Sobral, J.J. Matthee, P.N. Best, I. Smail, A.A. Khostovan, B. Milvang-Jensen,
J.-W. Kim, J. Stott, J. Calhau, H. Nayyeri, B. Mobasher, Monthly Notices of the
Royal Astronomical Society 451 (2015) 2303–2323.
date_created: 2022-07-14T09:02:22Z
date_published: 2015-08-11T00:00:00Z
date_updated: 2022-08-19T08:23:18Z
day: '11'
doi: 10.1093/mnras/stv1076
extern: '1'
external_id:
arxiv:
- '1502.06602'
intvolume: ' 451'
issue: '3'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- 'galaxies: evolution'
- 'galaxies: formation'
- 'galaxies: luminosity function'
- mass function
- 'cosmology: observations'
- early Universe
- large-scale structure of Universe
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1502.06602
month: '08'
oa: 1
oa_version: Preprint
page: 2303-2323
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'CF-HiZELS, an ∼10 deg2 emission-line survey with spectroscopic follow-up:
Hα, [O III] + Hβ and [O II] luminosity functions at z = 0.8, 1.4 and 2.2 '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 451
year: '2015'
...
---
_id: '11581'
abstract:
- lang: eng
text: Using wide-field narrow-band surveys, we provide a new measurement of the
z = 6.6 Lymanα emitter (LAE) luminosity function (LF), which constraints the bright
end for the first time. We use a combination of archival narrow-band NB921 data
in UDS and new NB921 measurements in SA22 and COSMOS/UltraVISTA, all observed
with the Subaru telescope, with a total area of ∼5 deg2. We exclude lower redshift
interlopers by using broad-band optical and near-infrared photometry and also
exclude three supernovae with data split over multiple epochs. Combining the UDS
and COSMOS samples, we find no evolution of the bright end of the Lyα LF between
z = 5.7 and 6.6, which is supported by spectroscopic follow-up, and conclude that
sources with Himiko-like luminosity are not as rare as previously thought, with
number densities of ∼1.5 × 10−5 Mpc−3. Combined with our wide-field SA22 measurements,
our results indicate a non-Schechter-like bright end of the LF at z = 6.6 and
a different evolution of observed faint and bright LAEs, overcoming cosmic variance.
This differential evolution is also seen in the spectroscopic follow-up of UV-selected
galaxies and is now also confirmed for LAEs, and we argue that it may be an effect
of reionization. Using a toy model, we show that such differential evolution of
the LF is expected, since brighter sources are able to ionize their surroundings
earlier, such that Lyα photons are able to escape. Our targets are excellent candidates
for detailed follow-up studies and provide the possibility to give a unique view
on the earliest stages in the formation of galaxies and reionization process.
acknowledgement: "We thank the anonymous referee for the comments and suggestions
which have improved the quality of this work. We thank Masami Ouchi for his useful
comments on an earlier version of this paper. JM acknowledges the support of a Huygens
PhD fellowship from Leiden University and is thankful for the hospitality of the
Center for Astronomy and Astrophysics of the University of Lisbon where part of
this research has been done. DS acknowledges financial support from the Netherlands
Organization for Scientific research (NWO) through a Veni fellowship, from FCT through
a FCT Investigator Starting Grant and Start-up Grant (IF/01154/2012/CP0189/CT0010)
and from FCT grant PEstOE/FIS/UI2751/2014. HR acknowledges support from the ERC
Advanced Investigator programme NewClusters 321271. We acknowledge the award of
ESO DDT time (294.A-5018) for providing the possibility of a timely publication
of this work.\r\nBased on observations with the Subaru Telescope (Programme IDs:
our observations: S14A-086; archival: S05B-027, S06A-025, S06B-010, S07A-013, S07B-008,
S08B-008 and S09A-017) and the W.M. Keck Observatory. The Subaru telescope is operated
by the National Astronomical Observatory of Japan. The W.M. Keck Observatory is
operated as a scientific partnership among the California Institute of Technology,
the University of California and the National Aeronautics and Space Administration.
Based on observations made with ESO Telescopes at the La Silla Paranal Observatory
under programme ID 294.A-5018. Based on observations obtained with MegaPrime/Megacam,
a joint project of CFHT and CEA/IRFU, at the Canada–France-Hawaii Telescope (CFHT)
which is operated by the National Research Council (NRC) of Canada, the Institut
National des Science de l’Univers of the Centre National de la Recherche Scientifique
(CNRS) of France, and the University of Hawaii. This work is based in part on data
products produced at Terapix available at the Canadian Astronomy Data Centre as
part of the CFHT Legacy Survey, a collaborative project of NRC and CNRS. Based on
data products from observations made with ESO Telescopes at the La Silla Paranal
Observatory under ESO programme ID 179.A-2005 and on data products produced by TERAPIX
and the Cambridge Astronomy Survey Unit on behalf of the UltraVISTA consortium.\r\nIn
addition to the CFHT-LS and COSMOS-UltraVISTA surveys, we are grateful for the excellent
data sets from the UKIRT-DXS, SXDF and S-COSMOS survey teams, without these legacy
surveys, this research would have been impossible. We have benefited greatly from
the public available programming language PYTHON, including the NUMPY, MATPLOTLIB,
PYFITS, SCIPY and ASTROPY packages, the astronomical imaging tools SEXTRACTOR, SWARP
and SCAMP and the indispensable TOPCAT analysis tool (Taylor 2013)"
article_processing_charge: No
article_type: original
author:
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: David
full_name: Sobral, David
last_name: Sobral
- first_name: Sérgio
full_name: Santos, Sérgio
last_name: Santos
- first_name: Huub
full_name: Röttgering, Huub
last_name: Röttgering
- first_name: Behnam
full_name: Darvish, Behnam
last_name: Darvish
- first_name: Bahram
full_name: Mobasher, Bahram
last_name: Mobasher
citation:
ama: 'Matthee JJ, Sobral D, Santos S, Röttgering H, Darvish B, Mobasher B. Identification
of the brightest Lyα emitters at z = 6.6: implications for the evolution of the
luminosity function in the reionization era. Monthly Notices of the Royal Astronomical
Society. 2015;451(1):400-417. doi:10.1093/mnras/stv947'
apa: 'Matthee, J. J., Sobral, D., Santos, S., Röttgering, H., Darvish, B., &
Mobasher, B. (2015). Identification of the brightest Lyα emitters at z = 6.6:
implications for the evolution of the luminosity function in the reionization
era. Monthly Notices of the Royal Astronomical Society. Oxford University
Press. https://doi.org/10.1093/mnras/stv947'
chicago: 'Matthee, Jorryt J, David Sobral, Sérgio Santos, Huub Röttgering, Behnam
Darvish, and Bahram Mobasher. “Identification of the Brightest Lyα Emitters at
z = 6.6: Implications for the Evolution of the Luminosity Function in the Reionization
Era.” Monthly Notices of the Royal Astronomical Society. Oxford University
Press, 2015. https://doi.org/10.1093/mnras/stv947.'
ieee: 'J. J. Matthee, D. Sobral, S. Santos, H. Röttgering, B. Darvish, and B. Mobasher,
“Identification of the brightest Lyα emitters at z = 6.6: implications for the
evolution of the luminosity function in the reionization era,” Monthly Notices
of the Royal Astronomical Society, vol. 451, no. 1. Oxford University Press,
pp. 400–417, 2015.'
ista: 'Matthee JJ, Sobral D, Santos S, Röttgering H, Darvish B, Mobasher B. 2015.
Identification of the brightest Lyα emitters at z = 6.6: implications for the
evolution of the luminosity function in the reionization era. Monthly Notices
of the Royal Astronomical Society. 451(1), 400–417.'
mla: 'Matthee, Jorryt J., et al. “Identification of the Brightest Lyα Emitters at
z = 6.6: Implications for the Evolution of the Luminosity Function in the Reionization
Era.” Monthly Notices of the Royal Astronomical Society, vol. 451, no.
1, Oxford University Press, 2015, pp. 400–17, doi:10.1093/mnras/stv947.'
short: J.J. Matthee, D. Sobral, S. Santos, H. Röttgering, B. Darvish, B. Mobasher,
Monthly Notices of the Royal Astronomical Society 451 (2015) 400–417.
date_created: 2022-07-14T11:57:03Z
date_published: 2015-07-21T00:00:00Z
date_updated: 2022-08-19T08:25:25Z
day: '21'
doi: 10.1093/mnras/stv947
extern: '1'
external_id:
arxiv:
- '1502.07355'
intvolume: ' 451'
issue: '1'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1502.07355
month: '07'
oa: 1
oa_version: Preprint
page: 400-417
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Identification of the brightest Lyα emitters at z = 6.6: implications for
the evolution of the luminosity function in the reionization era'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 451
year: '2015'
...
---
_id: '11579'
abstract:
- lang: eng
text: CR7 is the brightest z = 6.6 Ly α emitter (LAE) known to date, and spectroscopic
follow-up by Sobral et al. suggests that CR7 might host Population (Pop) III stars.
We examine this interpretation using cosmological hydrodynamical simulations.
Several simulated galaxies show the same ‘Pop III wave’ pattern observed in CR7.
However, to reproduce the extreme CR7 Ly α/He II1640 line luminosities (Lα/HeII)
a top-heavy initial mass function and a massive ( ≳ 107 M⊙) Pop III burst with
age ≲ 2 Myr are required. Assuming that the observed properties of Ly α and He II
emission are typical for Pop III, we predict that in the COSMOS/UDS/SA22 fields,
14 out of the 30 LAEs at z = 6.6 with Lα > 1043.3 erg s−1 should also host Pop
III stars producing an observable LHeII≳1042.7ergs−1. As an alternate explanation,
we explore the possibility that CR7 is instead powered by accretion on to a direct
collapse black hole. Our model predicts Lα, LHeII, and X-ray luminosities that
are in agreement with the observations. In any case, the observed properties of
CR7 indicate that this galaxy is most likely powered by sources formed from pristine
gas. We propose that further X-ray observations can distinguish between the two
above scenarios.
acknowledgement: SS acknowledges support from the Netherlands Organization for Scientific
research (NWO), VENI grant 639.041.233. RS acknowledges support from the European
Research Council under the European Union (FP/2007-2013)/ERC grant agreement no.
306476. DS acknowledges (i) financial support from the NWO through a Veni fellowship
and (ii) funding from FCT through a FCT Investigator Starting Grant and Start-up
Grant (IF/01154/2012/CP0189/CT0010) and from FCT grant PEstOE/FIS/UI2751/2014.
article_processing_charge: No
article_type: original
author:
- first_name: A.
full_name: Pallottini, A.
last_name: Pallottini
- first_name: A.
full_name: Ferrara, A.
last_name: Ferrara
- first_name: F.
full_name: Pacucci, F.
last_name: Pacucci
- first_name: S.
full_name: Gallerani, S.
last_name: Gallerani
- first_name: S.
full_name: Salvadori, S.
last_name: Salvadori
- first_name: R.
full_name: Schneider, R.
last_name: Schneider
- first_name: D.
full_name: Schaerer, D.
last_name: Schaerer
- first_name: D.
full_name: Sobral, D.
last_name: Sobral
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
citation:
ama: 'Pallottini A, Ferrara A, Pacucci F, et al. The brightest Lyα emitter: Pop
III or black hole? Monthly Notices of the Royal Astronomical Society. 2015;453(3):2465-2470.
doi:10.1093/mnras/stv1795'
apa: 'Pallottini, A., Ferrara, A., Pacucci, F., Gallerani, S., Salvadori, S., Schneider,
R., … Matthee, J. J. (2015). The brightest Lyα emitter: Pop III or black hole?
Monthly Notices of the Royal Astronomical Society. Oxford University Press.
https://doi.org/10.1093/mnras/stv1795'
chicago: 'Pallottini, A., A. Ferrara, F. Pacucci, S. Gallerani, S. Salvadori, R.
Schneider, D. Schaerer, D. Sobral, and Jorryt J Matthee. “The Brightest Lyα Emitter:
Pop III or Black Hole?” Monthly Notices of the Royal Astronomical Society.
Oxford University Press, 2015. https://doi.org/10.1093/mnras/stv1795.'
ieee: 'A. Pallottini et al., “The brightest Lyα emitter: Pop III or black
hole?,” Monthly Notices of the Royal Astronomical Society, vol. 453, no.
3. Oxford University Press, pp. 2465–2470, 2015.'
ista: 'Pallottini A, Ferrara A, Pacucci F, Gallerani S, Salvadori S, Schneider R,
Schaerer D, Sobral D, Matthee JJ. 2015. The brightest Lyα emitter: Pop III or
black hole? Monthly Notices of the Royal Astronomical Society. 453(3), 2465–2470.'
mla: 'Pallottini, A., et al. “The Brightest Lyα Emitter: Pop III or Black Hole?”
Monthly Notices of the Royal Astronomical Society, vol. 453, no. 3, Oxford
University Press, 2015, pp. 2465–70, doi:10.1093/mnras/stv1795.'
short: A. Pallottini, A. Ferrara, F. Pacucci, S. Gallerani, S. Salvadori, R. Schneider,
D. Schaerer, D. Sobral, J.J. Matthee, Monthly Notices of the Royal Astronomical
Society 453 (2015) 2465–2470.
date_created: 2022-07-14T08:58:36Z
date_published: 2015-11-01T00:00:00Z
date_updated: 2022-08-19T08:19:23Z
day: '01'
doi: 10.1093/mnras/stv1795
extern: '1'
external_id:
arxiv:
- '1506.07173'
intvolume: ' 453'
issue: '3'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- black hole physics
- 'stars: Population III'
- 'galaxies: high-redshift'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1506.07173
month: '11'
oa: 1
oa_version: Preprint
page: 2465-2470
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The brightest Lyα emitter: Pop III or black hole?'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 453
year: '2015'
...
---
_id: '11668'
abstract:
- lang: eng
text: "We study multiple keyword sponsored search auctions with budgets. Each keyword
has multiple ad slots with a click-through rate. The bidders have additive valuations,
which are linear in the click-through rates, and budgets, which are restricting
their overall payments. Additionally, the number of slots per keyword assigned
to a bidder is bounded.\r\n\r\nWe show the following results: (1) We give the
first mechanism for multiple keywords, where click-through rates differ among
slots. Our mechanism is incentive compatible in expectation, individually rational
in expectation, and Pareto optimal. (2) We study the combinatorial setting, where
each bidder is only interested in a subset of the keywords. We give an incentive
compatible, individually rational, Pareto-optimal, and deterministic mechanism
for identical click-through rates. (3) We give an impossibility result for incentive
compatible, individually rational, Pareto-optimal, and deterministic mechanisms
for bidders with diminishing marginal valuations."
article_number: '2'
article_processing_charge: No
article_type: original
author:
- first_name: Riccardo
full_name: Colini-Baldeschi, Riccardo
last_name: Colini-Baldeschi
- first_name: Stefano
full_name: Leonardi, Stefano
last_name: Leonardi
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Martin
full_name: Starnberger, Martin
last_name: Starnberger
citation:
ama: Colini-Baldeschi R, Leonardi S, Henzinger MH, Starnberger M. On multiple keyword
sponsored search auctions with budgets. ACM Transactions on Economics and Computation.
2015;4(1). doi:10.1145/2818357
apa: Colini-Baldeschi, R., Leonardi, S., Henzinger, M. H., & Starnberger, M.
(2015). On multiple keyword sponsored search auctions with budgets. ACM Transactions
on Economics and Computation. Association for Computing Machinery. https://doi.org/10.1145/2818357
chicago: Colini-Baldeschi, Riccardo, Stefano Leonardi, Monika H Henzinger, and Martin
Starnberger. “On Multiple Keyword Sponsored Search Auctions with Budgets.” ACM
Transactions on Economics and Computation. Association for Computing Machinery,
2015. https://doi.org/10.1145/2818357.
ieee: R. Colini-Baldeschi, S. Leonardi, M. H. Henzinger, and M. Starnberger, “On
multiple keyword sponsored search auctions with budgets,” ACM Transactions
on Economics and Computation, vol. 4, no. 1. Association for Computing Machinery,
2015.
ista: Colini-Baldeschi R, Leonardi S, Henzinger MH, Starnberger M. 2015. On multiple
keyword sponsored search auctions with budgets. ACM Transactions on Economics
and Computation. 4(1), 2.
mla: Colini-Baldeschi, Riccardo, et al. “On Multiple Keyword Sponsored Search Auctions
with Budgets.” ACM Transactions on Economics and Computation, vol. 4, no.
1, 2, Association for Computing Machinery, 2015, doi:10.1145/2818357.
short: R. Colini-Baldeschi, S. Leonardi, M.H. Henzinger, M. Starnberger, ACM Transactions
on Economics and Computation 4 (2015).
date_created: 2022-07-27T11:54:56Z
date_published: 2015-12-05T00:00:00Z
date_updated: 2023-02-09T10:03:35Z
day: '05'
doi: 10.1145/2818357
extern: '1'
intvolume: ' 4'
issue: '1'
keyword:
- Algorithms
- Economics
- Clinching ascending auction
- auctions with budgets
- Sponsored search auctions
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.cs.univie.ac.at/3510/
month: '12'
oa: 1
oa_version: Submitted Version
publication: ACM Transactions on Economics and Computation
publication_identifier:
eissn:
- 2167-8383
issn:
- 2167-8375
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: On multiple keyword sponsored search auctions with budgets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2015'
...
---
_id: '11669'
abstract:
- lang: eng
text: We study individual rational, Pareto-optimal, and incentive compatible mechanisms
for auctions with heterogeneous items and budget limits. We consider settings
with multiunit demand and additive valuations. For single-dimensional valuations
we prove a positive result for randomized mechanisms, and a negative result for
deterministic mechanisms. While the positive result allows for private budgets,
the negative result is for public budgets. For multidimensional valuations and
public budgets we prove an impossibility result that applies to deterministic
and randomized mechanisms. Taken together this shows the power of randomization
in certain settings with heterogeneous items, but it also shows its limitations.
article_number: '4'
article_processing_charge: No
article_type: original
author:
- first_name: Paul
full_name: Dütting, Paul
last_name: Dütting
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Martin
full_name: Starnberger, Martin
last_name: Starnberger
citation:
ama: Dütting P, Henzinger MH, Starnberger M. Auctions for heterogeneous items and
budget limits. ACM Transactions on Economics and Computation. 2015;4(1).
doi:10.1145/2818351
apa: Dütting, P., Henzinger, M. H., & Starnberger, M. (2015). Auctions for heterogeneous
items and budget limits. ACM Transactions on Economics and Computation.
Association for Computing Machinery. https://doi.org/10.1145/2818351
chicago: Dütting, Paul, Monika H Henzinger, and Martin Starnberger. “Auctions for
Heterogeneous Items and Budget Limits.” ACM Transactions on Economics and Computation.
Association for Computing Machinery, 2015. https://doi.org/10.1145/2818351.
ieee: P. Dütting, M. H. Henzinger, and M. Starnberger, “Auctions for heterogeneous
items and budget limits,” ACM Transactions on Economics and Computation,
vol. 4, no. 1. Association for Computing Machinery, 2015.
ista: Dütting P, Henzinger MH, Starnberger M. 2015. Auctions for heterogeneous items
and budget limits. ACM Transactions on Economics and Computation. 4(1), 4.
mla: Dütting, Paul, et al. “Auctions for Heterogeneous Items and Budget Limits.”
ACM Transactions on Economics and Computation, vol. 4, no. 1, 4, Association
for Computing Machinery, 2015, doi:10.1145/2818351.
short: P. Dütting, M.H. Henzinger, M. Starnberger, ACM Transactions on Economics
and Computation 4 (2015).
date_created: 2022-07-27T12:09:15Z
date_published: 2015-12-05T00:00:00Z
date_updated: 2022-09-09T12:08:37Z
day: '05'
doi: 10.1145/2818351
extern: '1'
external_id:
arxiv:
- '1209.6448'
intvolume: ' 4'
issue: '1'
keyword:
- Algorithmic game theory
- auction theory
- Clinching auction
- Pareto optimality
- Budget limits
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1209.6448
month: '12'
oa: 1
oa_version: Preprint
publication: ACM Transactions on Economics and Computation
publication_identifier:
eissn:
- 2167-8383
issn:
- 2167-8375
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auctions for heterogeneous items and budget limits
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2015'
...
---
_id: '11774'
abstract:
- lang: eng
text: "Combinatorial auctions (CA) are a well-studied area in algorithmic mechanism
design. However, contrary to the standard model, empirical studies suggest that
a bidder’s valuation often does not depend solely on the goods assigned to him.
For instance, in adwords auctions an advertiser might not want his ads to be displayed
next to his competitors’ ads. In this paper, we propose and analyze several natural
graph-theoretic models that incorporate such negative externalities, in which
bidders form a directed conflict graph with maximum out-degree Δ. We design algorithms
and truthful mechanisms for social welfare maximization that attain approximation
ratios depending on Δ.\r\n\r\nFor CA, our results are twofold: (1) A lottery that
eliminates conflicts by discarding bidders/items independent of the bids. It allows
to apply any truthful \U0001D6FC-approximation mechanism for conflict-free valuations
and yields an \U0001D4AA(\U0001D6FCΔ)-approximation mechanism. (2) For fractionally
sub-additive valuations, we design a rounding algorithm via a novel combination
of a semi-definite program and a linear program, resulting in a cone program;
the approximation ratio is \U0001D4AA((ΔloglogΔ)/logΔ). The ratios are almost
optimal given existing hardness results.\r\n\r\nFor adwords auctions, we present
several algorithms for the most relevant scenario when the number of items is
small. In particular, we design a truthful mechanism with approximation ratio
\U0001D45C(Δ) when the number of items is only logarithmic in the number of bidders."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Yun Kuen
full_name: Cheung, Yun Kuen
last_name: Cheung
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Martin
full_name: Hoefer, Martin
last_name: Hoefer
- first_name: Martin
full_name: Starnberger, Martin
last_name: Starnberger
citation:
ama: 'Cheung YK, Henzinger MH, Hoefer M, Starnberger M. Combinatorial auctions with
conflict-based externalities. In: 11th International Conference on Web and
Internet Economics. Vol 9470. Springer Nature; 2015:230–243. doi:10.1007/978-3-662-48995-6_17'
apa: 'Cheung, Y. K., Henzinger, M. H., Hoefer, M., & Starnberger, M. (2015).
Combinatorial auctions with conflict-based externalities. In 11th International
Conference on Web and Internet Economics (Vol. 9470, pp. 230–243). Amsterdam,
Netherlands: Springer Nature. https://doi.org/10.1007/978-3-662-48995-6_17'
chicago: Cheung, Yun Kuen, Monika H Henzinger, Martin Hoefer, and Martin Starnberger.
“Combinatorial Auctions with Conflict-Based Externalities.” In 11th International
Conference on Web and Internet Economics, 9470:230–243. Springer Nature, 2015.
https://doi.org/10.1007/978-3-662-48995-6_17.
ieee: Y. K. Cheung, M. H. Henzinger, M. Hoefer, and M. Starnberger, “Combinatorial
auctions with conflict-based externalities,” in 11th International Conference
on Web and Internet Economics, Amsterdam, Netherlands, 2015, vol. 9470, pp.
230–243.
ista: 'Cheung YK, Henzinger MH, Hoefer M, Starnberger M. 2015. Combinatorial auctions
with conflict-based externalities. 11th International Conference on Web and Internet
Economics. WINE: International Conference on Web and Internet Economics, LNCS,
vol. 9470, 230–243.'
mla: Cheung, Yun Kuen, et al. “Combinatorial Auctions with Conflict-Based Externalities.”
11th International Conference on Web and Internet Economics, vol. 9470,
Springer Nature, 2015, pp. 230–243, doi:10.1007/978-3-662-48995-6_17.
short: Y.K. Cheung, M.H. Henzinger, M. Hoefer, M. Starnberger, in:, 11th International
Conference on Web and Internet Economics, Springer Nature, 2015, pp. 230–243.
conference:
end_date: 2015-12-12
location: Amsterdam, Netherlands
name: 'WINE: International Conference on Web and Internet Economics'
start_date: 2015-12-09
date_created: 2022-08-08T13:54:32Z
date_published: 2015-12-09T00:00:00Z
date_updated: 2023-02-10T09:08:30Z
day: '09'
doi: 10.1007/978-3-662-48995-6_17
extern: '1'
external_id:
arxiv:
- '1509.09147'
intvolume: ' 9470'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1509.09147
month: '12'
oa: 1
oa_version: Preprint
page: 230–243
publication: 11th International Conference on Web and Internet Economics
publication_identifier:
eisbn:
- '9783662489956'
isbn:
- '9783662489949'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Combinatorial auctions with conflict-based externalities
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9470
year: '2015'
...
---
_id: '11773'
abstract:
- lang: eng
text: "Ad exchanges are an emerging platform for trading advertisement slots on
the web with billions of dollars revenue per year. Every time a user visits a
web page, the publisher of that web page can ask an ad exchange to auction off
the ad slots on this page to determine which advertisements are shown at which
price. Due to the high volume of traffic, ad networks typically act as mediators
for individual advertisers at ad exchanges. If multiple advertisers in an ad network
are interested in the ad slots of the same auction, the ad network might use a
“local” auction to resell the obtained ad slots among its advertisers.\r\n\r\nIn
this work we want to deepen the theoretical understanding of these new markets
by analyzing them from the viewpoint of combinatorial auctions. Prior work studied
mostly single-item auctions, while we allow the advertisers to express richer
preferences over multiple items. We develop a game-theoretic model for the entanglement
of the central auction at the ad exchange with the local auctions at the ad networks.
We consider the incentives of all three involved parties and suggest a three-party
competitive equilibrium, an extension of the Walrasian equilibrium that ensures
envy-freeness for all participants. We show the existence of a three-party competitive
equilibrium and a polynomial-time algorithm to find one for gross-substitute bidder
valuations."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Oren
full_name: Ben-Zwi, Oren
last_name: Ben-Zwi
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
citation:
ama: 'Ben-Zwi O, Henzinger MH, Loitzenbauer V. Ad exchange: Envy-free auctions with
mediators. In: 11th International Conference on Web and Internet Economics.
Vol 9470. Springer Nature; 2015:104–117. doi:10.1007/978-3-662-48995-6_8'
apa: 'Ben-Zwi, O., Henzinger, M. H., & Loitzenbauer, V. (2015). Ad exchange:
Envy-free auctions with mediators. In 11th International Conference on Web
and Internet Economics (Vol. 9470, pp. 104–117). Amsterdam, Netherlands: Springer
Nature. https://doi.org/10.1007/978-3-662-48995-6_8'
chicago: 'Ben-Zwi, Oren, Monika H Henzinger, and Veronika Loitzenbauer. “Ad Exchange:
Envy-Free Auctions with Mediators.” In 11th International Conference on Web
and Internet Economics, 9470:104–117. Springer Nature, 2015. https://doi.org/10.1007/978-3-662-48995-6_8.'
ieee: 'O. Ben-Zwi, M. H. Henzinger, and V. Loitzenbauer, “Ad exchange: Envy-free
auctions with mediators,” in 11th International Conference on Web and Internet
Economics, Amsterdam, Netherlands, 2015, vol. 9470, pp. 104–117.'
ista: 'Ben-Zwi O, Henzinger MH, Loitzenbauer V. 2015. Ad exchange: Envy-free auctions
with mediators. 11th International Conference on Web and Internet Economics. WINE:
International Conference on Web and Internet Economics, LNCS, vol. 9470, 104–117.'
mla: 'Ben-Zwi, Oren, et al. “Ad Exchange: Envy-Free Auctions with Mediators.” 11th
International Conference on Web and Internet Economics, vol. 9470, Springer
Nature, 2015, pp. 104–117, doi:10.1007/978-3-662-48995-6_8.'
short: O. Ben-Zwi, M.H. Henzinger, V. Loitzenbauer, in:, 11th International Conference
on Web and Internet Economics, Springer Nature, 2015, pp. 104–117.
conference:
end_date: 2015-09-12
location: Amsterdam, Netherlands
name: 'WINE: International Conference on Web and Internet Economics'
start_date: 2015-09-09
date_created: 2022-08-08T13:33:56Z
date_published: 2015-12-09T00:00:00Z
date_updated: 2023-02-10T09:06:23Z
day: '09'
doi: 10.1007/978-3-662-48995-6_8
extern: '1'
external_id:
arxiv:
- '1604.05562'
intvolume: ' 9470'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1604.05562
month: '12'
oa: 1
oa_version: Preprint
page: 104–117
publication: 11th International Conference on Web and Internet Economics
publication_identifier:
eisbn:
- '9783662489956'
isbn:
- '9783662489949'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Ad exchange: Envy-free auctions with mediators'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9470
year: '2015'
...
---
_id: '11785'
abstract:
- lang: eng
text: "Recently we presented the first algorithm for maintaining the set of nodes
reachable from a source node in a directed graph that is modified by edge deletions
with \U0001D45C(\U0001D45A\U0001D45B) total update time, where \U0001D45A is the
number of edges and \U0001D45B is the number of nodes in the graph [Henzinger
et al. STOC 2014]. The algorithm is a combination of several different algorithms,
each for a different \U0001D45A vs. \U0001D45B trade-off. For the case of \U0001D45A=Θ(\U0001D45B1.5)
the running time is \U0001D442(\U0001D45B2.47), just barely below \U0001D45A\U0001D45B=Θ(\U0001D45B2.5).
In this paper we simplify the previous algorithm using new algorithmic ideas and
achieve an improved running time of \U0001D442̃ (min(\U0001D45A7/6\U0001D45B2/3,\U0001D45A3/4\U0001D45B5/4+\U0001D45C(1),\U0001D45A2/3\U0001D45B4/3+\U0001D45C(1)+\U0001D45A3/7\U0001D45B12/7+\U0001D45C(1))).
This gives, e.g., \U0001D442(\U0001D45B2.36) for the notorious case \U0001D45A=Θ(\U0001D45B1.5).
We obtain the same upper bounds for the problem of maintaining the strongly connected
components of a directed graph undergoing edge deletions. Our algorithms are correct
with high probabililty against an oblivious adversary."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Danupon
full_name: Nanongkai, Danupon
last_name: Nanongkai
citation:
ama: 'Henzinger MH, Krinninger S, Nanongkai D. Improved algorithms for decremental
single-source reachability on directed graphs. In: 42nd International Colloquium
on Automata, Languages and Programming. Vol 9134. Springer Nature; 2015:725-736.
doi:10.1007/978-3-662-47672-7_59'
apa: 'Henzinger, M. H., Krinninger, S., & Nanongkai, D. (2015). Improved algorithms
for decremental single-source reachability on directed graphs. In 42nd International
Colloquium on Automata, Languages and Programming (Vol. 9134, pp. 725–736).
Kyoto, Japan: Springer Nature. https://doi.org/10.1007/978-3-662-47672-7_59'
chicago: Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “Improved
Algorithms for Decremental Single-Source Reachability on Directed Graphs.” In
42nd International Colloquium on Automata, Languages and Programming, 9134:725–36.
Springer Nature, 2015. https://doi.org/10.1007/978-3-662-47672-7_59.
ieee: M. H. Henzinger, S. Krinninger, and D. Nanongkai, “Improved algorithms for
decremental single-source reachability on directed graphs,” in 42nd International
Colloquium on Automata, Languages and Programming, Kyoto, Japan, 2015, vol.
9134, pp. 725–736.
ista: 'Henzinger MH, Krinninger S, Nanongkai D. 2015. Improved algorithms for decremental
single-source reachability on directed graphs. 42nd International Colloquium on
Automata, Languages and Programming. ICALP: International Colloquium on Automata,
Languages, and Programming, LNCS, vol. 9134, 725–736.'
mla: Henzinger, Monika H., et al. “Improved Algorithms for Decremental Single-Source
Reachability on Directed Graphs.” 42nd International Colloquium on Automata,
Languages and Programming, vol. 9134, Springer Nature, 2015, pp. 725–36, doi:10.1007/978-3-662-47672-7_59.
short: M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 42nd International Colloquium
on Automata, Languages and Programming, Springer Nature, 2015, pp. 725–736.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
start_date: 2015-07-06
date_created: 2022-08-11T08:51:32Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-10T09:10:26Z
day: '01'
doi: 10.1007/978-3-662-47672-7_59
extern: '1'
external_id:
arxiv:
- '1612.03856'
intvolume: ' 9134'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1612.03856
month: '01'
oa: 1
oa_version: Preprint
page: 725 - 736
publication: 42nd International Colloquium on Automata, Languages and Programming
publication_identifier:
isbn:
- '9783662476710'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improved algorithms for decremental single-source reachability on directed
graphs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9134
year: '2015'
...
---
_id: '11787'
abstract:
- lang: eng
text: "We present faster algorithms for computing the 2-edge and 2-vertex strongly
connected components of a directed graph. While in undirected graphs the 2-edge
and 2-vertex connected components can be found in linear time, in directed graphs
with m edges and n vertices only rather simple O(m n)-time algorithms were known.
We use a hierarchical sparsification technique to obtain algorithms that run in
time \U0001D442(\U0001D45B2). For 2-edge strongly connected components our algorithm
gives the first running time improvement in 20 years. Additionally we present
an \U0001D442(\U0001D45A2/log\U0001D45B)-time algorithm for 2-edge strongly connected
components, and thus improve over the O(m n) running time also when \U0001D45A=\U0001D442(\U0001D45B).
Our approach extends to k-edge and k-vertex strongly connected components for
any constant k with a running time of \U0001D442(\U0001D45B2log\U0001D45B) for
k-edge-connectivity and \U0001D442(\U0001D45B3) for k-vertex-connectivity."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
citation:
ama: 'Henzinger MH, Krinninger S, Loitzenbauer V. Finding 2-edge and 2-vertex strongly
connected components in quadratic time. In: 2nd International Colloquium on
Automata, Languages and Programming. Vol 9134. Springer Nature; 2015:713-724.
doi:10.1007/978-3-662-47672-7_58'
apa: 'Henzinger, M. H., Krinninger, S., & Loitzenbauer, V. (2015). Finding 2-edge
and 2-vertex strongly connected components in quadratic time. In 2nd International
Colloquium on Automata, Languages and Programming (Vol. 9134, pp. 713–724).
Kyoto, Japan: Springer Nature. https://doi.org/10.1007/978-3-662-47672-7_58'
chicago: Henzinger, Monika H, Sebastian Krinninger, and Veronika Loitzenbauer. “Finding
2-Edge and 2-Vertex Strongly Connected Components in Quadratic Time.” In 2nd
International Colloquium on Automata, Languages and Programming, 9134:713–24.
Springer Nature, 2015. https://doi.org/10.1007/978-3-662-47672-7_58.
ieee: M. H. Henzinger, S. Krinninger, and V. Loitzenbauer, “Finding 2-edge and 2-vertex
strongly connected components in quadratic time,” in 2nd International Colloquium
on Automata, Languages and Programming, Kyoto, Japan, 2015, vol. 9134, pp.
713–724.
ista: 'Henzinger MH, Krinninger S, Loitzenbauer V. 2015. Finding 2-edge and 2-vertex
strongly connected components in quadratic time. 2nd International Colloquium
on Automata, Languages and Programming. ICALP: International Colloquium on Automata,
Languages, and Programming, LNCS, vol. 9134, 713–724.'
mla: Henzinger, Monika H., et al. “Finding 2-Edge and 2-Vertex Strongly Connected
Components in Quadratic Time.” 2nd International Colloquium on Automata, Languages
and Programming, vol. 9134, Springer Nature, 2015, pp. 713–24, doi:10.1007/978-3-662-47672-7_58.
short: M.H. Henzinger, S. Krinninger, V. Loitzenbauer, in:, 2nd International Colloquium
on Automata, Languages and Programming, Springer Nature, 2015, pp. 713–724.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
start_date: 2015-07-06
date_created: 2022-08-11T09:38:34Z
date_published: 2015-07-06T00:00:00Z
date_updated: 2023-02-10T09:21:47Z
day: '06'
doi: 10.1007/978-3-662-47672-7_58
extern: '1'
external_id:
arxiv:
- '1412.6466'
intvolume: ' 9134'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1412.6466
month: '07'
oa: 1
oa_version: Preprint
page: 713 - 724
publication: 2nd International Colloquium on Automata, Languages and Programming
publication_identifier:
isbn:
- '9783662476710'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Finding 2-edge and 2-vertex strongly connected components in quadratic time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9134
year: '2015'
...
---
_id: '11788'
abstract:
- lang: eng
text: "Ad exchanges are becoming an increasingly popular way to sell advertisement
slots on the internet. An ad exchange is basically a spot market for ad impressions.
A publisher who has already signed contracts reserving advertisement impressions
on his pages can choose between assigning a new ad impression for a new page view
to a contracted advertiser or to sell it at an ad exchange. This leads to an online
revenue maximization problem for the publisher. Given a new impression to sell
decide whether (a) to assign it to a contracted advertiser and if so to which
one or (b) to sell it at the ad exchange and if so at which reserve price. We
make no assumptions about the distribution of the advertiser valuations that participate
in the ad exchange and show that there exists a simple primal-dual based online
algorithm, whose lower bound for the revenue converges to \U0001D445\U0001D434\U0001D437\U0001D44B+\U0001D445\U0001D434(1−1/\U0001D452),
where \U0001D445\U0001D434\U0001D437\U0001D44B is the revenue that the optimum
algorithm achieves from the ad exchange and \U0001D445\U0001D434 is the revenue
that the optimum algorithm achieves from the contracted advertisers."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Wolfgang
full_name: Dvořák, Wolfgang
last_name: Dvořák
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: 'Dvořák W, Henzinger MH. Online ad assignment with an ad exchange. In: 12th
International Workshop of Approximation and Online Algorithms. Vol 8952. Springer
Nature; 2015:156–167. doi:10.1007/978-3-319-18263-6_14'
apa: 'Dvořák, W., & Henzinger, M. H. (2015). Online ad assignment with an ad
exchange. In 12th International Workshop of Approximation and Online Algorithms
(Vol. 8952, pp. 156–167). Wroclaw, Poland: Springer Nature. https://doi.org/10.1007/978-3-319-18263-6_14'
chicago: Dvořák, Wolfgang, and Monika H Henzinger. “Online Ad Assignment with an
Ad Exchange.” In 12th International Workshop of Approximation and Online Algorithms,
8952:156–167. Springer Nature, 2015. https://doi.org/10.1007/978-3-319-18263-6_14.
ieee: W. Dvořák and M. H. Henzinger, “Online ad assignment with an ad exchange,”
in 12th International Workshop of Approximation and Online Algorithms,
Wroclaw, Poland, 2015, vol. 8952, pp. 156–167.
ista: 'Dvořák W, Henzinger MH. 2015. Online ad assignment with an ad exchange. 12th
International Workshop of Approximation and Online Algorithms. WAOA: International
Workshop on Approximation and Online Algorithms, LNCS, vol. 8952, 156–167.'
mla: Dvořák, Wolfgang, and Monika H. Henzinger. “Online Ad Assignment with an Ad
Exchange.” 12th International Workshop of Approximation and Online Algorithms,
vol. 8952, Springer Nature, 2015, pp. 156–167, doi:10.1007/978-3-319-18263-6_14.
short: W. Dvořák, M.H. Henzinger, in:, 12th International Workshop of Approximation
and Online Algorithms, Springer Nature, 2015, pp. 156–167.
conference:
end_date: 2014-09-12
location: Wroclaw, Poland
name: 'WAOA: International Workshop on Approximation and Online Algorithms'
start_date: 2014-09-11
date_created: 2022-08-11T09:43:32Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-10T09:26:06Z
day: '01'
doi: 10.1007/978-3-319-18263-6_14
extern: '1'
external_id:
arxiv:
- '1604.05603'
intvolume: ' 8952'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1604.05603
month: '01'
oa: 1
oa_version: Preprint
page: 156–167
publication: 12th International Workshop of Approximation and Online Algorithms
publication_identifier:
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Online ad assignment with an ad exchange
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8952
year: '2015'
...
---
_id: '11786'
abstract:
- lang: eng
text: "In this paper, we develop a dynamic version of the primal-dual method for
optimization problems, and apply it to obtain the following results. (1) For the
dynamic set-cover problem, we maintain an \U0001D442(\U0001D4532)-approximately
optimal solution in \U0001D442(\U0001D453⋅log(\U0001D45A+\U0001D45B)) amortized
update time, where \U0001D453 is the maximum “frequency” of an element, \U0001D45B
is the number of sets, and \U0001D45A is the maximum number of elements in the
universe at any point in time. (2) For the dynamic \U0001D44F-matching problem,
we maintain an \U0001D442(1)-approximately optimal solution in \U0001D442(log3\U0001D45B)
amortized update time, where \U0001D45B is the number of nodes in the graph."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sayan
full_name: Bhattacharya, Sayan
last_name: Bhattacharya
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Giuseppe F.
full_name: Italiano, Giuseppe F.
last_name: Italiano
citation:
ama: 'Bhattacharya S, Henzinger MH, Italiano GF. Design of dynamic algorithms via
primal-dual method. In: 42nd International Colloquium on Automata, Languages
and Programming. Vol 9134. Springer Nature; 2015:206-218. doi:10.1007/978-3-662-47672-7_17'
apa: 'Bhattacharya, S., Henzinger, M. H., & Italiano, G. F. (2015). Design of
dynamic algorithms via primal-dual method. In 42nd International Colloquium
on Automata, Languages and Programming (Vol. 9134, pp. 206–218). Kyoto, Japan:
Springer Nature. https://doi.org/10.1007/978-3-662-47672-7_17'
chicago: Bhattacharya, Sayan, Monika H Henzinger, and Giuseppe F. Italiano. “Design
of Dynamic Algorithms via Primal-Dual Method.” In 42nd International Colloquium
on Automata, Languages and Programming, 9134:206–18. Springer Nature, 2015.
https://doi.org/10.1007/978-3-662-47672-7_17.
ieee: S. Bhattacharya, M. H. Henzinger, and G. F. Italiano, “Design of dynamic algorithms
via primal-dual method,” in 42nd International Colloquium on Automata, Languages
and Programming, Kyoto, Japan, 2015, vol. 9134, pp. 206–218.
ista: 'Bhattacharya S, Henzinger MH, Italiano GF. 2015. Design of dynamic algorithms
via primal-dual method. 42nd International Colloquium on Automata, Languages and
Programming. ICALP: International Colloquium on Automata, Languages, and Programming,
LNCS, vol. 9134, 206–218.'
mla: Bhattacharya, Sayan, et al. “Design of Dynamic Algorithms via Primal-Dual Method.”
42nd International Colloquium on Automata, Languages and Programming, vol.
9134, Springer Nature, 2015, pp. 206–18, doi:10.1007/978-3-662-47672-7_17.
short: S. Bhattacharya, M.H. Henzinger, G.F. Italiano, in:, 42nd International Colloquium
on Automata, Languages and Programming, Springer Nature, 2015, pp. 206–218.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
start_date: 2015-07-06
date_created: 2022-08-11T09:28:49Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-10T09:13:31Z
day: '01'
doi: 10.1007/978-3-662-47672-7_17
extern: '1'
external_id:
arxiv:
- '1604.05337'
intvolume: ' 9134'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1604.05337
month: '01'
oa: 1
oa_version: Preprint
page: 206 - 218
publication: 42nd International Colloquium on Automata, Languages and Programming
publication_identifier:
isbn:
- '9783662476710'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Design of dynamic algorithms via primal-dual method
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9134
year: '2015'
...
---
_id: '11845'
abstract:
- lang: eng
text: "Phylogenetic diversity (PD) is a measure of biodiversity based on the evolutionary
history of species. Here, we discuss several optimization problems related to
the use of PD, and the more general measure split diversity (SD), in conservation
prioritization.\r\nDepending on the conservation goal and the information available
about species, one can construct optimization routines that incorporate various
conservation constraints. We demonstrate how this information can be used to select
sets of species for conservation action. Specifically, we discuss the use of species'
geographic distributions, the choice of candidates under economic pressure, and
the use of predator–prey interactions between the species in a community to define
viability constraints.\r\nDespite such optimization problems falling into the
area of NP hard problems, it is possible to solve them in a reasonable amount
of time using integer programming. We apply integer linear programming to a variety
of models for conservation prioritization that incorporate the SD measure.\r\nWe
exemplarily show the results for two data sets: the Cape region of South Africa
and a Caribbean coral reef community. Finally, we provide user-friendly software
at http://www.cibiv.at/software/pda."
article_processing_charge: No
article_type: original
author:
- first_name: Olga
full_name: Chernomor, Olga
last_name: Chernomor
- first_name: Bui Quang
full_name: Minh, Bui Quang
last_name: Minh
- first_name: Félix
full_name: Forest, Félix
last_name: Forest
- first_name: Steffen
full_name: Klaere, Steffen
last_name: Klaere
- first_name: Travis
full_name: Ingram, Travis
last_name: Ingram
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Arndt
full_name: von Haeseler, Arndt
last_name: von Haeseler
citation:
ama: Chernomor O, Minh BQ, Forest F, et al. Split diversity in constrained conservation
prioritization using integer linear programming. Methods in Ecology and Evolution.
2015;6(1):83-91. doi:10.1111/2041-210x.12299
apa: Chernomor, O., Minh, B. Q., Forest, F., Klaere, S., Ingram, T., Henzinger,
M. H., & von Haeseler, A. (2015). Split diversity in constrained conservation
prioritization using integer linear programming. Methods in Ecology and Evolution.
Wiley. https://doi.org/10.1111/2041-210x.12299
chicago: Chernomor, Olga, Bui Quang Minh, Félix Forest, Steffen Klaere, Travis Ingram,
Monika H Henzinger, and Arndt von Haeseler. “Split Diversity in Constrained Conservation
Prioritization Using Integer Linear Programming.” Methods in Ecology and Evolution.
Wiley, 2015. https://doi.org/10.1111/2041-210x.12299.
ieee: O. Chernomor et al., “Split diversity in constrained conservation prioritization
using integer linear programming,” Methods in Ecology and Evolution, vol.
6, no. 1. Wiley, pp. 83–91, 2015.
ista: Chernomor O, Minh BQ, Forest F, Klaere S, Ingram T, Henzinger MH, von Haeseler
A. 2015. Split diversity in constrained conservation prioritization using integer
linear programming. Methods in Ecology and Evolution. 6(1), 83–91.
mla: Chernomor, Olga, et al. “Split Diversity in Constrained Conservation Prioritization
Using Integer Linear Programming.” Methods in Ecology and Evolution, vol.
6, no. 1, Wiley, 2015, pp. 83–91, doi:10.1111/2041-210x.12299.
short: O. Chernomor, B.Q. Minh, F. Forest, S. Klaere, T. Ingram, M.H. Henzinger,
A. von Haeseler, Methods in Ecology and Evolution 6 (2015) 83–91.
date_created: 2022-08-16T06:43:49Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-17T09:30:08Z
day: '01'
ddc:
- '570'
doi: 10.1111/2041-210x.12299
extern: '1'
external_id:
pmid:
- '25893087'
file:
- access_level: open_access
checksum: 880e78f09f0ac99cb351c48dc97623b6
content_type: application/pdf
creator: asandaue
date_created: 2022-08-16T06:52:53Z
date_updated: 2022-08-16T06:52:53Z
file_id: '11846'
file_name: 2015_MethodsInEcologyAndEvolutionChernomor.pdf
file_size: 411415
relation: main_file
success: 1
file_date_updated: 2022-08-16T06:52:53Z
has_accepted_license: '1'
intvolume: ' 6'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 83-91
pmid: 1
publication: Methods in Ecology and Evolution
publication_identifier:
eissn:
- 2041-210X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Split diversity in constrained conservation prioritization using integer linear
programming
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '11868'
abstract:
- lang: eng
text: "Consider the following Online Boolean Matrix-Vector Multiplication problem:
We are given an n x n matrix M and will receive n column-vectors of size n, denoted
by v1, ..., vn, one by one. After seeing each vector vi, we have to output the
product Mvi before we can see the next vector. A naive algorithm can solve this
problem using O(n3) time in total, and its running time can be slightly improved
to O(n3/log2 n) [Williams SODA'07]. We show that a conjecture that there is no
truly subcubic (O(n3-ε)) time algorithm for this problem can be used to exhibit
the underlying polynomial time hardness shared by many dynamic problems. For a
number of problems, such as subgraph connectivity, Pagh's problem, d-failure connectivity,
decremental single-source shortest paths, and decremental transitive closure,
this conjecture implies tight hardness results. Thus, proving or disproving this
conjecture will be very interesting as it will either imply several tight unconditional
lower bounds or break through a common barrier that blocks progress with these
problems. This conjecture might also be considered as strong evidence against
any further improvement for these problems since refuting it will imply a major
breakthrough for combinatorial Boolean matrix multiplication and other long-standing
problems if the term \"combinatorial algorithms\" is interpreted as \"Strassen-like
algorithms\" [Ballard et al. SPAA'11].\r\n\r\nThe conjecture also leads to hardness
results for problems that were previously based on diverse problems and conjectures
-- such as 3SUM, combinatorial Boolean matrix multiplication, triangle detection,
and multiphase -- thus providing a uniform way to prove polynomial hardness results
for dynamic algorithms; some of the new proofs are also simpler or even become
trivial. The conjecture also leads to stronger and new, non-trivial, hardness
results, e.g., for the fully-dynamic densest subgraph and diameter problems."
article_number: 21-30
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Danupon
full_name: Nanongkai, Danupon
last_name: Nanongkai
- first_name: Thatchaphol
full_name: Saranurak, Thatchaphol
last_name: Saranurak
citation:
ama: 'Henzinger MH, Krinninger S, Nanongkai D, Saranurak T. Unifying and strengthening
hardness for dynamic problems via the online matrix-vector multiplication conjecture.
In: 47th Annual ACM Symposium on Theory of Computing. Association for Computing
Machinery; 2015. doi:10.1145/2746539.2746609'
apa: 'Henzinger, M. H., Krinninger, S., Nanongkai, D., & Saranurak, T. (2015).
Unifying and strengthening hardness for dynamic problems via the online matrix-vector
multiplication conjecture. In 47th Annual ACM Symposium on Theory of Computing.
Portland, OR, United States: Association for Computing Machinery. https://doi.org/10.1145/2746539.2746609'
chicago: Henzinger, Monika H, Sebastian Krinninger, Danupon Nanongkai, and Thatchaphol
Saranurak. “Unifying and Strengthening Hardness for Dynamic Problems via the Online
Matrix-Vector Multiplication Conjecture.” In 47th Annual ACM Symposium on Theory
of Computing. Association for Computing Machinery, 2015. https://doi.org/10.1145/2746539.2746609.
ieee: M. H. Henzinger, S. Krinninger, D. Nanongkai, and T. Saranurak, “Unifying
and strengthening hardness for dynamic problems via the online matrix-vector multiplication
conjecture,” in 47th Annual ACM Symposium on Theory of Computing, Portland,
OR, United States, 2015.
ista: 'Henzinger MH, Krinninger S, Nanongkai D, Saranurak T. 2015. Unifying and
strengthening hardness for dynamic problems via the online matrix-vector multiplication
conjecture. 47th Annual ACM Symposium on Theory of Computing. STOC: Symposium
on Theory of Computing, 21–30.'
mla: Henzinger, Monika H., et al. “Unifying and Strengthening Hardness for Dynamic
Problems via the Online Matrix-Vector Multiplication Conjecture.” 47th Annual
ACM Symposium on Theory of Computing, 21–30, Association for Computing Machinery,
2015, doi:10.1145/2746539.2746609.
short: M.H. Henzinger, S. Krinninger, D. Nanongkai, T. Saranurak, in:, 47th Annual
ACM Symposium on Theory of Computing, Association for Computing Machinery, 2015.
conference:
end_date: 2015-06-17
location: Portland, OR, United States
name: 'STOC: Symposium on Theory of Computing'
start_date: 2015-06-14
date_created: 2022-08-16T09:31:21Z
date_published: 2015-06-14T00:00:00Z
date_updated: 2023-02-17T11:09:54Z
day: '14'
doi: 10.1145/2746539.2746609
extern: '1'
external_id:
arxiv:
- '1511.06773'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1511.06773
month: '06'
oa: 1
oa_version: Preprint
publication: 47th Annual ACM Symposium on Theory of Computing
publication_identifier:
isbn:
- 978-145033536-2
issn:
- '0737.8017'
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unifying and strengthening hardness for dynamic problems via the online matrix-vector
multiplication conjecture
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '11869'
abstract:
- lang: eng
text: "While in many graph mining applications it is crucial to handle a stream
of updates efficiently in terms of both time and space, not much was known about
achieving such type of algorithm. In this paper we study this issue for a problem
which lies at the core of many graph mining applications called densest subgraph
problem. We develop an algorithm that achieves time- and space-efficiency for
this problem simultaneously. It is one of the first of its kind for graph problems
to the best of our knowledge.\r\n\r\nGiven an input graph, the densest subgraph
is the subgraph that maximizes the ratio between the number of edges and the number
of nodes. For any ε>0, our algorithm can, with high probability, maintain a (4+ε)-approximate
solution under edge insertions and deletions using ~O(n) space and ~O(1) amortized
time per update; here, $n$ is the number of nodes in the graph and ~O hides the
O(polylog_{1+ε} n) term. The approximation ratio can be improved to (2+ε) with
more time. It can be extended to a (2+ε)-approximation sublinear-time algorithm
and a distributed-streaming algorithm. Our algorithm is the first streaming algorithm
that can maintain the densest subgraph in one pass. Prior to this, no algorithm
could do so even in the special case of an incremental stream and even when there
is no time restriction. The previously best algorithm in this setting required
O(log n) passes [BahmaniKV12]. The space required by our algorithm is tight up
to a polylogarithmic factor."
article_processing_charge: No
author:
- first_name: Sayan
full_name: Bhattacharya, Sayan
last_name: Bhattacharya
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Danupon
full_name: Nanongkai, Danupon
last_name: Nanongkai
- first_name: Charalampos
full_name: Tsourakakis, Charalampos
last_name: Tsourakakis
citation:
ama: 'Bhattacharya S, Henzinger MH, Nanongkai D, Tsourakakis C. Space- and time-efficient
algorithm for maintaining dense subgraphs on one-pass dynamic streams. In: 47th
Annual ACM Symposium on Theory of Computing. Association for Computing Machinery;
2015:173-182. doi:10.1145/2746539.2746592'
apa: 'Bhattacharya, S., Henzinger, M. H., Nanongkai, D., & Tsourakakis, C. (2015).
Space- and time-efficient algorithm for maintaining dense subgraphs on one-pass
dynamic streams. In 47th Annual ACM Symposium on Theory of Computing (pp.
173–182). Portland, OR, United States: Association for Computing Machinery. https://doi.org/10.1145/2746539.2746592'
chicago: Bhattacharya, Sayan, Monika H Henzinger, Danupon Nanongkai, and Charalampos
Tsourakakis. “Space- and Time-Efficient Algorithm for Maintaining Dense Subgraphs
on One-Pass Dynamic Streams.” In 47th Annual ACM Symposium on Theory of Computing,
173–82. Association for Computing Machinery, 2015. https://doi.org/10.1145/2746539.2746592.
ieee: S. Bhattacharya, M. H. Henzinger, D. Nanongkai, and C. Tsourakakis, “Space-
and time-efficient algorithm for maintaining dense subgraphs on one-pass dynamic
streams,” in 47th Annual ACM Symposium on Theory of Computing, Portland,
OR, United States, 2015, pp. 173–182.
ista: 'Bhattacharya S, Henzinger MH, Nanongkai D, Tsourakakis C. 2015. Space- and
time-efficient algorithm for maintaining dense subgraphs on one-pass dynamic streams.
47th Annual ACM Symposium on Theory of Computing. STOC: Symposium on Theory of
Computing, 173–182.'
mla: Bhattacharya, Sayan, et al. “Space- and Time-Efficient Algorithm for Maintaining
Dense Subgraphs on One-Pass Dynamic Streams.” 47th Annual ACM Symposium on
Theory of Computing, Association for Computing Machinery, 2015, pp. 173–82,
doi:10.1145/2746539.2746592.
short: S. Bhattacharya, M.H. Henzinger, D. Nanongkai, C. Tsourakakis, in:, 47th
Annual ACM Symposium on Theory of Computing, Association for Computing Machinery,
2015, pp. 173–182.
conference:
end_date: 2015-06-17
location: Portland, OR, United States
name: 'STOC: Symposium on Theory of Computing'
start_date: 2015-06-14
date_created: 2022-08-16T09:36:48Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-17T11:17:03Z
day: '01'
doi: 10.1145/2746539.2746592
extern: '1'
external_id:
arxiv:
- '1504.02268'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1504.02268
month: '06'
oa: 1
oa_version: Preprint
page: 173 - 182
publication: 47th Annual ACM Symposium on Theory of Computing
publication_identifier:
isbn:
- 978-145033536-2
issn:
- 0737-8017
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: Space- and time-efficient algorithm for maintaining dense subgraphs on one-pass
dynamic streams
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '11837'
abstract:
- lang: eng
text: "Online social networks allow the collection of large amounts of data about
the influence between users connected by a friendship-like relationship. When
distributing items among agents forming a social network, this information allows
us to exploit network externalities that each agent receives from his neighbors
that get the same item. In this paper we consider Friends-of-Friends (2-hop) network
externalities, i.e., externalities that not only depend on the neighbors that
get the same item but also on neighbors of neighbors. For these externalities
we study a setting where multiple different items are assigned to unit-demand
agents. Specifically, we study the problem of welfare maximization under different
types of externality functions. Let n be the number of agents and m be the number
of items. Our contributions are the following: (1) We show that welfare maximization
is APX-hard; we show that even for step functions with 2-hop (and also with 1-hop)
externalities it is NP-hard to approximate social welfare better than (1-1/e).
(2) On the positive side we present (i) an O(sqrt n)-approximation algorithm for
general concave externality functions,\r\n(ii) an O(\\log m)-approximation algorithm
for linear externality functions, and (iii) an (1-1/e)\\frac{1}{6}-approximation
algorithm for 2-hop step function externalities. We also improve the result from
[6] for 1-hop step function externalities by giving a (1-1/e)/2-approximation
algorithm."
alternative_title:
- LIPIcs
article_processing_charge: No
author:
- first_name: Sayan
full_name: Bhattacharya, Sayan
last_name: Bhattacharya
- first_name: Wolfgang
full_name: Dvorák, Wolfgang
last_name: Dvorák
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: ' Martin'
full_name: Starnberger, Martin
last_name: Starnberger
citation:
ama: 'Bhattacharya S, Dvorák W, Henzinger MH, Starnberger Martin. Welfare maximization
with friends-of-friends network externalities. In: 32nd International Symposium
on Theoretical Aspects of Computer Science. Vol 30. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik; 2015:90-102. doi:10.4230/LIPICS.STACS.2015.90'
apa: 'Bhattacharya, S., Dvorák, W., Henzinger, M. H., & Starnberger, Martin.
(2015). Welfare maximization with friends-of-friends network externalities. In
32nd International Symposium on Theoretical Aspects of Computer Science
(Vol. 30, pp. 90–102). Garching, Germany: Schloss Dagstuhl - Leibniz-Zentrum für
Informatik. https://doi.org/10.4230/LIPICS.STACS.2015.90'
chicago: Bhattacharya, Sayan, Wolfgang Dvorák, Monika H Henzinger, and Martin Starnberger.
“Welfare Maximization with Friends-of-Friends Network Externalities.” In 32nd
International Symposium on Theoretical Aspects of Computer Science, 30:90–102.
Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. https://doi.org/10.4230/LIPICS.STACS.2015.90.
ieee: S. Bhattacharya, W. Dvorák, M. H. Henzinger, and Martin Starnberger, “Welfare
maximization with friends-of-friends network externalities,” in 32nd International
Symposium on Theoretical Aspects of Computer Science, Garching, Germany, 2015,
vol. 30, pp. 90–102.
ista: 'Bhattacharya S, Dvorák W, Henzinger MH, Starnberger Martin. 2015. Welfare
maximization with friends-of-friends network externalities. 32nd International
Symposium on Theoretical Aspects of Computer Science. STACS: Symposium on Theoretical
Aspects of Computer Science, LIPIcs, vol. 30, 90–102.'
mla: Bhattacharya, Sayan, et al. “Welfare Maximization with Friends-of-Friends Network
Externalities.” 32nd International Symposium on Theoretical Aspects of Computer
Science, vol. 30, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015,
pp. 90–102, doi:10.4230/LIPICS.STACS.2015.90.
short: S. Bhattacharya, W. Dvorák, M.H. Henzinger, Martin Starnberger, in:, 32nd
International Symposium on Theoretical Aspects of Computer Science, Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2015, pp. 90–102.
conference:
end_date: 2015-03-07
location: Garching, Germany
name: 'STACS: Symposium on Theoretical Aspects of Computer Science'
start_date: 2015-03-04
date_created: 2022-08-12T11:39:40Z
date_published: 2015-02-26T00:00:00Z
date_updated: 2023-02-21T16:32:37Z
day: '26'
doi: 10.4230/LIPICS.STACS.2015.90
extern: '1'
intvolume: ' 30'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.4230/LIPICS.STACS.2015.90
month: '02'
oa: 1
oa_version: Published Version
page: 90-102
publication: 32nd International Symposium on Theoretical Aspects of Computer Science
publication_identifier:
isbn:
- 978-3-939897-78-1
issn:
- 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
record:
- id: '11903'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Welfare maximization with friends-of-friends network externalities
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2015'
...
---
_id: '11901'
abstract:
- lang: eng
text: We consider auctions of indivisible items to unit-demand bidders with budgets.
This setting was suggested as an expressive model for single sponsored search
auctions. Prior work presented mechanisms that compute bidder-optimal outcomes
and are truthful for a restricted set of inputs, i.e., inputs in so-called general
position. This condition is easily violated. We provide the first mechanism that
is truthful in expectation for all inputs and achieves for each bidder no worse
utility than the bidder-optimal outcome. Additionally we give a complete characterization
for which inputs mechanisms that compute bidder-optimal outcomes are truthful.
article_processing_charge: No
article_type: original
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
citation:
ama: Henzinger MH, Loitzenbauer V. Truthful unit-demand auctions with budgets revisited.
Theoretical Computer Science. 2015;573:1-15. doi:10.1016/j.tcs.2015.01.033
apa: Henzinger, M. H., & Loitzenbauer, V. (2015). Truthful unit-demand auctions
with budgets revisited. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/j.tcs.2015.01.033
chicago: Henzinger, Monika H, and Veronika Loitzenbauer. “Truthful Unit-Demand Auctions
with Budgets Revisited.” Theoretical Computer Science. Elsevier, 2015.
https://doi.org/10.1016/j.tcs.2015.01.033.
ieee: M. H. Henzinger and V. Loitzenbauer, “Truthful unit-demand auctions with budgets
revisited,” Theoretical Computer Science, vol. 573. Elsevier, pp. 1–15,
2015.
ista: Henzinger MH, Loitzenbauer V. 2015. Truthful unit-demand auctions with budgets
revisited. Theoretical Computer Science. 573, 1–15.
mla: Henzinger, Monika H., and Veronika Loitzenbauer. “Truthful Unit-Demand Auctions
with Budgets Revisited.” Theoretical Computer Science, vol. 573, Elsevier,
2015, pp. 1–15, doi:10.1016/j.tcs.2015.01.033.
short: M.H. Henzinger, V. Loitzenbauer, Theoretical Computer Science 573 (2015)
1–15.
date_created: 2022-08-17T09:06:53Z
date_published: 2015-03-30T00:00:00Z
date_updated: 2023-02-17T14:50:04Z
day: '30'
doi: 10.1016/j.tcs.2015.01.033
extern: '1'
intvolume: ' 573'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.tcs.2015.01.033
month: '03'
oa: 1
oa_version: None
page: 1-15
publication: Theoretical Computer Science
publication_identifier:
issn:
- 0304-3975
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Truthful unit-demand auctions with budgets revisited
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 573
year: '2015'
...
---
_id: '121'
abstract:
- lang: eng
text: We show that the simplest building blocks of origami-based materials - rigid,
degree-four vertices - are generically multistable. The existence of two distinct
branches of folding motion emerging from the flat state suggests at least bistability,
but we show how nonlinearities in the folding motions allow generic vertex geometries
to have as many as five stable states. In special geometries with collinear folds
and symmetry, more branches emerge leading to as many as six stable states. Tuning
the fold energy parameters, we show how monostability is also possible. Finally,
we show how to program the stability features of a single vertex into a periodic
fold tessellation. The resulting metasheets provide a previously unanticipated
functionality - tunable and switchable shape and size via multistability.
acknowledgement: B. G. C. acknowledges support from FOM, and S. W. and M. v. H. acknowledge
support from NWO.
article_number: '055503'
author:
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
- first_name: Rémi
full_name: Menaut, Rémi
last_name: Menaut
- first_name: Bryan
full_name: Chen, Bryan
last_name: Chen
- first_name: Martin
full_name: Van Hecke, Martin
last_name: Van Hecke
citation:
ama: 'Waitukaitis SR, Menaut R, Chen B, Van Hecke M. Origami multistability: From
single vertices to metasheets. APS Physics, Physical Review Letters. 2015;114(5).
doi:10.1103/PhysRevLett.114.055503'
apa: 'Waitukaitis, S. R., Menaut, R., Chen, B., & Van Hecke, M. (2015). Origami
multistability: From single vertices to metasheets. APS Physics, Physical Review
Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.114.055503'
chicago: 'Waitukaitis, Scott R, Rémi Menaut, Bryan Chen, and Martin Van Hecke. “Origami
Multistability: From Single Vertices to Metasheets.” APS Physics, Physical
Review Letters. American Physical Society, 2015. https://doi.org/10.1103/PhysRevLett.114.055503.'
ieee: 'S. R. Waitukaitis, R. Menaut, B. Chen, and M. Van Hecke, “Origami multistability:
From single vertices to metasheets,” APS Physics, Physical Review Letters,
vol. 114, no. 5. American Physical Society, 2015.'
ista: 'Waitukaitis SR, Menaut R, Chen B, Van Hecke M. 2015. Origami multistability:
From single vertices to metasheets. APS Physics, Physical Review Letters. 114(5),
055503.'
mla: 'Waitukaitis, Scott R., et al. “Origami Multistability: From Single Vertices
to Metasheets.” APS Physics, Physical Review Letters, vol. 114, no. 5,
055503, American Physical Society, 2015, doi:10.1103/PhysRevLett.114.055503.'
short: S.R. Waitukaitis, R. Menaut, B. Chen, M. Van Hecke, APS Physics, Physical
Review Letters 114 (2015).
date_created: 2018-12-11T11:44:44Z
date_published: 2015-02-04T00:00:00Z
date_updated: 2021-01-12T06:49:07Z
day: '04'
doi: 10.1103/PhysRevLett.114.055503
extern: '1'
external_id:
arxiv:
- '1408.1607'
intvolume: ' 114'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1408.1607
month: '02'
oa: 1
oa_version: Preprint
publication: APS Physics, Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '7933'
quality_controlled: '1'
status: public
title: 'Origami multistability: From single vertices to metasheets'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2015'
...
---
_id: '1383'
abstract:
- lang: eng
text: In plants, vacuolar H+-ATPase (V-ATPase) activity acidifies both the trans-Golgi
network/early endosome (TGN/EE) and the vacuole. This dual V-ATPase function has
impeded our understanding of how the pH homeostasis within the plant TGN/EE controls
exo- and endocytosis. Here, we show that the weak V-ATPase mutant deetiolated3
(det3) displayed a pH increase in the TGN/EE, but not in the vacuole, strongly
impairing secretion and recycling of the brassinosteroid receptor and the cellulose
synthase complexes to the plasma membrane, in contrast to mutants lacking tonoplast-localized
V-ATPase activity only. The brassinosteroid insensitivity and the cellulose deficiency
defects in det3 were tightly correlated with reduced Golgi and TGN/EE motility.
Thus, our results provide strong evidence that acidification of the TGN/EE, but
not of the vacuole, is indispensable for functional secretion and recycling in
plants.
article_number: '15094'
article_processing_charge: No
article_type: original
author:
- first_name: Luo
full_name: Yu, Luo
last_name: Yu
- first_name: Stefan
full_name: Scholl, Stefan
last_name: Scholl
- first_name: Anett
full_name: Doering, Anett
last_name: Doering
- first_name: Zhang
full_name: Yi, Zhang
last_name: Yi
- first_name: Niloufer
full_name: Irani, Niloufer
last_name: Irani
- first_name: Simone
full_name: Di Rubbo, Simone
last_name: Di Rubbo
- first_name: Lutz
full_name: Neumetzler, Lutz
last_name: Neumetzler
- first_name: Praveen
full_name: Krishnamoorthy, Praveen
last_name: Krishnamoorthy
- first_name: Isabelle
full_name: Van Houtte, Isabelle
last_name: Van Houtte
- first_name: Evelien
full_name: Mylle, Evelien
last_name: Mylle
- first_name: Volker
full_name: Bischoff, Volker
last_name: Bischoff
- first_name: Samantha
full_name: Vernhettes, Samantha
last_name: Vernhettes
- first_name: Johan
full_name: Winne, Johan
last_name: Winne
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: York
full_name: Stierhof, York
last_name: Stierhof
- first_name: Karin
full_name: Schumacher, Karin
last_name: Schumacher
- first_name: Staffan
full_name: Persson, Staffan
last_name: Persson
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
citation:
ama: Yu L, Scholl S, Doering A, et al. V-ATPase activity in the TGN/EE is required
for exocytosis and recycling in Arabidopsis. Nature Plants. 2015;1(7).
doi:10.1038/nplants.2015.94
apa: Yu, L., Scholl, S., Doering, A., Yi, Z., Irani, N., Di Rubbo, S., … Russinova,
E. (2015). V-ATPase activity in the TGN/EE is required for exocytosis and recycling
in Arabidopsis. Nature Plants. Nature Publishing Group. https://doi.org/10.1038/nplants.2015.94
chicago: Yu, Luo, Stefan Scholl, Anett Doering, Zhang Yi, Niloufer Irani, Simone
Di Rubbo, Lutz Neumetzler, et al. “V-ATPase Activity in the TGN/EE Is Required
for Exocytosis and Recycling in Arabidopsis.” Nature Plants. Nature Publishing
Group, 2015. https://doi.org/10.1038/nplants.2015.94.
ieee: L. Yu et al., “V-ATPase activity in the TGN/EE is required for exocytosis
and recycling in Arabidopsis,” Nature Plants, vol. 1, no. 7. Nature Publishing
Group, 2015.
ista: Yu L, Scholl S, Doering A, Yi Z, Irani N, Di Rubbo S, Neumetzler L, Krishnamoorthy
P, Van Houtte I, Mylle E, Bischoff V, Vernhettes S, Winne J, Friml J, Stierhof
Y, Schumacher K, Persson S, Russinova E. 2015. V-ATPase activity in the TGN/EE
is required for exocytosis and recycling in Arabidopsis. Nature Plants. 1(7),
15094.
mla: Yu, Luo, et al. “V-ATPase Activity in the TGN/EE Is Required for Exocytosis
and Recycling in Arabidopsis.” Nature Plants, vol. 1, no. 7, 15094, Nature
Publishing Group, 2015, doi:10.1038/nplants.2015.94.
short: L. Yu, S. Scholl, A. Doering, Z. Yi, N. Irani, S. Di Rubbo, L. Neumetzler,
P. Krishnamoorthy, I. Van Houtte, E. Mylle, V. Bischoff, S. Vernhettes, J. Winne,
J. Friml, Y. Stierhof, K. Schumacher, S. Persson, E. Russinova, Nature Plants
1 (2015).
date_created: 2018-12-11T11:51:42Z
date_published: 2015-07-06T00:00:00Z
date_updated: 2021-01-12T06:50:18Z
day: '06'
department:
- _id: JiFr
doi: 10.1038/nplants.2015.94
external_id:
pmid:
- '27250258'
intvolume: ' 1'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905525/
month: '07'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Nature Plants
publication_status: published
publisher: Nature Publishing Group
publist_id: '5827'
quality_controlled: '1'
scopus_import: 1
status: public
title: V-ATPase activity in the TGN/EE is required for exocytosis and recycling in
Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2015'
...
---
_id: '1425'
abstract:
- lang: eng
text: 'In this work we aim at extending the theoretical foundations of lifelong
learning. Previous work analyzing this scenario is based on the assumption that
learning tasks are sampled i.i.d. from a task environment or limited to strongly
constrained data distributions. Instead, we study two scenarios when lifelong
learning is possible, even though the observed tasks do not form an i.i.d. sample:
first, when they are sampled from the same environment, but possibly with dependencies,
and second, when the task environment is allowed to change over time in a consistent
way. In the first case we prove a PAC-Bayesian theorem that can be seen as a direct
generalization of the analogous previous result for the i.i.d. case. For the second
scenario we propose to learn an inductive bias in form of a transfer procedure.
We present a generalization bound and show on a toy example how it can be used
to identify a beneficial transfer algorithm.'
alternative_title:
- Advances in Neural Information Processing Systems
author:
- first_name: Anastasia
full_name: Pentina, Anastasia
id: 42E87FC6-F248-11E8-B48F-1D18A9856A87
last_name: Pentina
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Pentina A, Lampert C. Lifelong learning with non-i.i.d. tasks. In: Vol 2015.
Neural Information Processing Systems; 2015:1540-1548.'
apa: 'Pentina, A., & Lampert, C. (2015). Lifelong learning with non-i.i.d. tasks
(Vol. 2015, pp. 1540–1548). Presented at the NIPS: Neural Information Processing
Systems, Montreal, Canada: Neural Information Processing Systems.'
chicago: Pentina, Anastasia, and Christoph Lampert. “Lifelong Learning with Non-i.i.d.
Tasks,” 2015:1540–48. Neural Information Processing Systems, 2015.
ieee: 'A. Pentina and C. Lampert, “Lifelong learning with non-i.i.d. tasks,” presented
at the NIPS: Neural Information Processing Systems, Montreal, Canada, 2015, vol.
2015, pp. 1540–1548.'
ista: 'Pentina A, Lampert C. 2015. Lifelong learning with non-i.i.d. tasks. NIPS:
Neural Information Processing Systems, Advances in Neural Information Processing
Systems, vol. 2015, 1540–1548.'
mla: Pentina, Anastasia, and Christoph Lampert. Lifelong Learning with Non-i.i.d.
Tasks. Vol. 2015, Neural Information Processing Systems, 2015, pp. 1540–48.
short: A. Pentina, C. Lampert, in:, Neural Information Processing Systems, 2015,
pp. 1540–1548.
conference:
end_date: 2015-12-12
location: Montreal, Canada
name: 'NIPS: Neural Information Processing Systems'
start_date: 2015-12-07
date_created: 2018-12-11T11:51:57Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:39Z
day: '01'
department:
- _id: ChLa
ec_funded: 1
intvolume: ' 2015'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://papers.nips.cc/paper/6007-lifelong-learning-with-non-iid-tasks
month: '01'
oa: 1
oa_version: None
page: 1540 - 1548
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '5781'
quality_controlled: '1'
scopus_import: 1
status: public
title: Lifelong learning with non-i.i.d. tasks
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2015
year: '2015'
...
---
_id: '1424'
abstract:
- lang: eng
text: We consider the problem of statistical computations with persistence diagrams,
a summary representation of topological features in data. These diagrams encode
persistent homology, a widely used invariant in topological data analysis. While
several avenues towards a statistical treatment of the diagrams have been explored
recently, we follow an alternative route that is motivated by the success of methods
based on the embedding of probability measures into reproducing kernel Hilbert
spaces. In fact, a positive definite kernel on persistence diagrams has recently
been proposed, connecting persistent homology to popular kernel-based learning
techniques such as support vector machines. However, important properties of that
kernel enabling a principled use in the context of probability measure embeddings
remain to be explored. Our contribution is to close this gap by proving universality
of a variant of the original kernel, and to demonstrate its effective use in twosample
hypothesis testing on synthetic as well as real-world data.
acknowledgement: This work was partially supported by the Austrian Science FUnd, project
no. KLI 00012.
alternative_title:
- Advances in Neural Information Processing Systems
author:
- first_name: Roland
full_name: Kwitt, Roland
last_name: Kwitt
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Marc
full_name: Niethammer, Marc
last_name: Niethammer
- first_name: Weili
full_name: Lin, Weili
last_name: Lin
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
citation:
ama: 'Kwitt R, Huber S, Niethammer M, Lin W, Bauer U. Statistical topological data
analysis-A kernel perspective. In: Vol 28. Neural Information Processing Systems;
2015:3070-3078.'
apa: 'Kwitt, R., Huber, S., Niethammer, M., Lin, W., & Bauer, U. (2015). Statistical
topological data analysis-A kernel perspective (Vol. 28, pp. 3070–3078). Presented
at the NIPS: Neural Information Processing Systems, Montreal, Canada: Neural Information
Processing Systems.'
chicago: Kwitt, Roland, Stefan Huber, Marc Niethammer, Weili Lin, and Ulrich Bauer.
“Statistical Topological Data Analysis-A Kernel Perspective,” 28:3070–78. Neural
Information Processing Systems, 2015.
ieee: 'R. Kwitt, S. Huber, M. Niethammer, W. Lin, and U. Bauer, “Statistical topological
data analysis-A kernel perspective,” presented at the NIPS: Neural Information
Processing Systems, Montreal, Canada, 2015, vol. 28, pp. 3070–3078.'
ista: 'Kwitt R, Huber S, Niethammer M, Lin W, Bauer U. 2015. Statistical topological
data analysis-A kernel perspective. NIPS: Neural Information Processing Systems,
Advances in Neural Information Processing Systems, vol. 28, 3070–3078.'
mla: Kwitt, Roland, et al. Statistical Topological Data Analysis-A Kernel Perspective.
Vol. 28, Neural Information Processing Systems, 2015, pp. 3070–78.
short: R. Kwitt, S. Huber, M. Niethammer, W. Lin, U. Bauer, in:, Neural Information
Processing Systems, 2015, pp. 3070–3078.
conference:
end_date: 2015-12-12
location: Montreal, Canada
name: 'NIPS: Neural Information Processing Systems'
start_date: 2015-12-07
date_created: 2018-12-11T11:51:56Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T06:50:38Z
day: '01'
department:
- _id: HeEd
intvolume: ' 28'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://papers.nips.cc/paper/5887-statistical-topological-data-analysis-a-kernel-perspective
month: '12'
oa: 1
oa_version: Submitted Version
page: 3070 - 3078
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '5782'
quality_controlled: '1'
status: public
title: Statistical topological data analysis-A kernel perspective
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 28
year: '2015'
...
---
_id: '1430'
abstract:
- lang: eng
text: Evolutionary algorithms (EAs) form a popular optimisation paradigm inspired
by natural evolution. In recent years the field of evolutionary computation has
developed a rigorous analytical theory to analyse their runtime on many illustrative
problems. Here we apply this theory to a simple model of natural evolution. In
the Strong Selection Weak Mutation (SSWM) evolutionary regime the time between
occurrence of new mutations is much longer than the time it takes for a new beneficial
mutation to take over the population. In this situation, the population only contains
copies of one genotype and evolution can be modelled as a (1+1)-type process where
the probability of accepting a new genotype (improvements or worsenings) depends
on the change in fitness. We present an initial runtime analysis of SSWM, quantifying
its performance for various parameters and investigating differences to the (1+1)
EA. We show that SSWM can have a moderate advantage over the (1+1) EA at crossing
fitness valleys and study an example where SSWM outperforms the (1+1) EA by taking
advantage of information on the fitness gradient.
author:
- first_name: Tiago
full_name: Paixao, Tiago
id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
last_name: Paixao
orcid: 0000-0003-2361-3953
- first_name: Dirk
full_name: Sudholt, Dirk
last_name: Sudholt
- first_name: Jorge
full_name: Heredia, Jorge
last_name: Heredia
- first_name: Barbora
full_name: Trubenova, Barbora
id: 42302D54-F248-11E8-B48F-1D18A9856A87
last_name: Trubenova
orcid: 0000-0002-6873-2967
citation:
ama: 'Paixao T, Sudholt D, Heredia J, Trubenova B. First steps towards a runtime
comparison of natural and artificial evolution. In: Proceedings of the 2015
Annual Conference on Genetic and Evolutionary Computation. ACM; 2015:1455-1462.
doi:10.1145/2739480.2754758'
apa: 'Paixao, T., Sudholt, D., Heredia, J., & Trubenova, B. (2015). First steps
towards a runtime comparison of natural and artificial evolution. In Proceedings
of the 2015 Annual Conference on Genetic and Evolutionary Computation (pp.
1455–1462). Madrid, Spain: ACM. https://doi.org/10.1145/2739480.2754758'
chicago: Paixao, Tiago, Dirk Sudholt, Jorge Heredia, and Barbora Trubenova. “First
Steps towards a Runtime Comparison of Natural and Artificial Evolution.” In Proceedings
of the 2015 Annual Conference on Genetic and Evolutionary Computation, 1455–62.
ACM, 2015. https://doi.org/10.1145/2739480.2754758.
ieee: T. Paixao, D. Sudholt, J. Heredia, and B. Trubenova, “First steps towards
a runtime comparison of natural and artificial evolution,” in Proceedings of
the 2015 Annual Conference on Genetic and Evolutionary Computation, Madrid,
Spain, 2015, pp. 1455–1462.
ista: 'Paixao T, Sudholt D, Heredia J, Trubenova B. 2015. First steps towards a
runtime comparison of natural and artificial evolution. Proceedings of the 2015
Annual Conference on Genetic and Evolutionary Computation. GECCO: Genetic and
evolutionary computation conference, 1455–1462.'
mla: Paixao, Tiago, et al. “First Steps towards a Runtime Comparison of Natural
and Artificial Evolution.” Proceedings of the 2015 Annual Conference on Genetic
and Evolutionary Computation, ACM, 2015, pp. 1455–62, doi:10.1145/2739480.2754758.
short: T. Paixao, D. Sudholt, J. Heredia, B. Trubenova, in:, Proceedings of the
2015 Annual Conference on Genetic and Evolutionary Computation, ACM, 2015, pp.
1455–1462.
conference:
end_date: 2015-07-15
location: Madrid, Spain
name: 'GECCO: Genetic and evolutionary computation conference'
start_date: 2015-07-11
date_created: 2018-12-11T11:51:58Z
date_published: 2015-07-11T00:00:00Z
date_updated: 2021-01-12T06:50:41Z
day: '11'
department:
- _id: NiBa
- _id: CaGu
doi: 10.1145/2739480.2754758
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1504.06260
month: '07'
oa: 1
oa_version: Preprint
page: 1455 - 1462
project:
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618091'
name: Speed of Adaptation in Population Genetics and Evolutionary Computation
publication: Proceedings of the 2015 Annual Conference on Genetic and Evolutionary
Computation
publication_status: published
publisher: ACM
publist_id: '5768'
quality_controlled: '1'
scopus_import: 1
status: public
title: First steps towards a runtime comparison of natural and artificial evolution
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1474'
abstract:
- lang: eng
text: Cryptographic access control offers selective access to encrypted data via
a combination of key management and functionality-rich cryptographic schemes,
such as attribute-based encryption. Using this approach, publicly available meta-data
may inadvertently leak information on the access policy that is enforced by cryptography,
which renders cryptographic access control unusable in settings where this information
is highly sensitive. We begin to address this problem by presenting rigorous definitions
for policy privacy in cryptographic access control. For concreteness we set our
results in the model of Role-Based Access Control (RBAC), where we identify and
formalize several different flavors of privacy, however, our framework should
serve as inspiration for other models of access control. Based on our insights
we propose a new system which significantly improves on the privacy properties
of state-of-the-art constructions. Our design is based on a novel type of privacy-preserving
attribute-based encryption, which we introduce and show how to instantiate. We
present our results in the context of a cryptographic RBAC system by Ferrara et
al. (CSF'13), which uses cryptography to control read access to files, while write
access is still delegated to trusted monitors. We give an extension of the construction
that permits cryptographic control over write access. Our construction assumes
that key management uses out-of-band channels between the policy enforcer and
the users but eliminates completely the need for monitoring read/write access
to the data.
article_processing_charge: No
author:
- first_name: Anna
full_name: Ferrara, Anna
last_name: Ferrara
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
- first_name: Bin
full_name: Liu, Bin
last_name: Liu
- first_name: Bogdan
full_name: Warinschi, Bogdan
last_name: Warinschi
citation:
ama: 'Ferrara A, Fuchsbauer G, Liu B, Warinschi B. Policy privacy in cryptographic
access control. In: IEEE; 2015:46-60. doi:10.1109/CSF.2015.11'
apa: 'Ferrara, A., Fuchsbauer, G., Liu, B., & Warinschi, B. (2015). Policy privacy
in cryptographic access control (pp. 46–60). Presented at the CSF: Computer Security
Foundations, Verona, Italy: IEEE. https://doi.org/10.1109/CSF.2015.11'
chicago: Ferrara, Anna, Georg Fuchsbauer, Bin Liu, and Bogdan Warinschi. “Policy
Privacy in Cryptographic Access Control,” 46–60. IEEE, 2015. https://doi.org/10.1109/CSF.2015.11.
ieee: 'A. Ferrara, G. Fuchsbauer, B. Liu, and B. Warinschi, “Policy privacy in cryptographic
access control,” presented at the CSF: Computer Security Foundations, Verona,
Italy, 2015, pp. 46–60.'
ista: 'Ferrara A, Fuchsbauer G, Liu B, Warinschi B. 2015. Policy privacy in cryptographic
access control. CSF: Computer Security Foundations, 46–60.'
mla: Ferrara, Anna, et al. Policy Privacy in Cryptographic Access Control.
IEEE, 2015, pp. 46–60, doi:10.1109/CSF.2015.11.
short: A. Ferrara, G. Fuchsbauer, B. Liu, B. Warinschi, in:, IEEE, 2015, pp. 46–60.
conference:
end_date: 2015-07-17
location: Verona, Italy
name: 'CSF: Computer Security Foundations'
start_date: 2015-07-13
date_created: 2018-12-11T11:52:14Z
date_published: 2015-09-04T00:00:00Z
date_updated: 2021-01-12T06:50:59Z
day: '04'
department:
- _id: KrPi
doi: 10.1109/CSF.2015.11
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://epubs.surrey.ac.uk/808055/
month: '09'
oa: 1
oa_version: Submitted Version
page: 46-60
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication_status: published
publisher: IEEE
publist_id: '5722'
quality_controlled: '1'
status: public
title: Policy privacy in cryptographic access control
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1473'
abstract:
- lang: eng
text: In this paper we survey geometric and arithmetic techniques to study the cohomology
of semiprojective hyperkähler manifolds including toric hyperkähler varieties,
Nakajima quiver varieties and moduli spaces of Higgs bundles on Riemann surfaces.
The resulting formulae for their Poincaré polynomials are combinatorial and representation
theoretical in nature. In particular we will look at their Betti numbers and will
establish some results and state some expectations on their asymptotic shape.
author:
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Fernando
full_name: Rodríguez Villegas, Fernando
last_name: Rodríguez Villegas
citation:
ama: Hausel T, Rodríguez Villegas F. Cohomology of large semiprojective hyperkähler
varieties. Asterisque. 2015;2015(370):113-156.
apa: Hausel, T., & Rodríguez Villegas, F. (2015). Cohomology of large semiprojective
hyperkähler varieties. Asterisque. Societe Mathematique de France.
chicago: Hausel, Tamás, and Fernando Rodríguez Villegas. “Cohomology of Large Semiprojective
Hyperkähler Varieties.” Asterisque. Societe Mathematique de France, 2015.
ieee: T. Hausel and F. Rodríguez Villegas, “Cohomology of large semiprojective hyperkähler
varieties,” Asterisque, vol. 2015, no. 370. Societe Mathematique de France,
pp. 113–156, 2015.
ista: Hausel T, Rodríguez Villegas F. 2015. Cohomology of large semiprojective hyperkähler
varieties. Asterisque. 2015(370), 113–156.
mla: Hausel, Tamás, and Fernando Rodríguez Villegas. “Cohomology of Large Semiprojective
Hyperkähler Varieties.” Asterisque, vol. 2015, no. 370, Societe Mathematique
de France, 2015, pp. 113–56.
short: T. Hausel, F. Rodríguez Villegas, Asterisque 2015 (2015) 113–156.
date_created: 2018-12-11T11:52:13Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:59Z
day: '01'
extern: 1
intvolume: ' 2015'
issue: '370'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.4914
month: '01'
oa: 1
page: 113 - 156
publication: Asterisque
publication_status: published
publisher: Societe Mathematique de France
publist_id: '5723'
quality_controlled: 0
status: public
title: Cohomology of large semiprojective hyperkähler varieties
type: review
volume: 2015
year: '2015'
...
---
_id: '1483'
abstract:
- lang: eng
text: Topological data analysis offers a rich source of valuable information to
study vision problems. Yet, so far we lack a theoretically sound connection to
popular kernel-based learning techniques, such as kernel SVMs or kernel PCA. In
this work, we establish such a connection by designing a multi-scale kernel for
persistence diagrams, a stable summary representation of topological features
in data. We show that this kernel is positive definite and prove its stability
with respect to the 1-Wasserstein distance. Experiments on two benchmark datasets
for 3D shape classification/retrieval and texture recognition show considerable
performance gains of the proposed method compared to an alternative approach that
is based on the recently introduced persistence landscapes.
author:
- first_name: Jan
full_name: Reininghaus, Jan
id: 4505473A-F248-11E8-B48F-1D18A9856A87
last_name: Reininghaus
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
- first_name: Roland
full_name: Kwitt, Roland
last_name: Kwitt
citation:
ama: 'Reininghaus J, Huber S, Bauer U, Kwitt R. A stable multi-scale kernel for
topological machine learning. In: IEEE; 2015:4741-4748. doi:10.1109/CVPR.2015.7299106'
apa: 'Reininghaus, J., Huber, S., Bauer, U., & Kwitt, R. (2015). A stable multi-scale
kernel for topological machine learning (pp. 4741–4748). Presented at the CVPR:
Computer Vision and Pattern Recognition, Boston, MA, USA: IEEE. https://doi.org/10.1109/CVPR.2015.7299106'
chicago: Reininghaus, Jan, Stefan Huber, Ulrich Bauer, and Roland Kwitt. “A Stable
Multi-Scale Kernel for Topological Machine Learning,” 4741–48. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7299106.
ieee: 'J. Reininghaus, S. Huber, U. Bauer, and R. Kwitt, “A stable multi-scale kernel
for topological machine learning,” presented at the CVPR: Computer Vision and
Pattern Recognition, Boston, MA, USA, 2015, pp. 4741–4748.'
ista: 'Reininghaus J, Huber S, Bauer U, Kwitt R. 2015. A stable multi-scale kernel
for topological machine learning. CVPR: Computer Vision and Pattern Recognition,
4741–4748.'
mla: Reininghaus, Jan, et al. A Stable Multi-Scale Kernel for Topological Machine
Learning. IEEE, 2015, pp. 4741–48, doi:10.1109/CVPR.2015.7299106.
short: J. Reininghaus, S. Huber, U. Bauer, R. Kwitt, in:, IEEE, 2015, pp. 4741–4748.
conference:
end_date: 2015-06-12
location: Boston, MA, USA
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:52:17Z
date_published: 2015-10-14T00:00:00Z
date_updated: 2021-01-12T06:51:03Z
day: '14'
department:
- _id: HeEd
doi: 10.1109/CVPR.2015.7299106
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1412.6821
month: '10'
oa: 1
oa_version: Preprint
page: 4741 - 4748
publication_identifier:
eisbn:
- '978-1-4673-6964-0 '
publication_status: published
publisher: IEEE
publist_id: '5709'
scopus_import: 1
status: public
title: A stable multi-scale kernel for topological machine learning
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1498'
abstract:
- lang: eng
text: Fault-tolerant distributed algorithms play an important role in many critical/high-availability
applications. These algorithms are notoriously difficult to implement correctly,
due to asynchronous communication and the occurrence of faults, such as the network
dropping messages or computers crashing. Nonetheless there is surprisingly little
language and verification support to build distributed systems based on fault-tolerant
algorithms. In this paper, we present some of the challenges that a designer has
to overcome to implement a fault-tolerant distributed system. Then we review different
models that have been proposed to reason about distributed algorithms and sketch
how such a model can form the basis for a domain-specific programming language.
Adopting a high-level programming model can simplify the programmer's life and
make the code amenable to automated verification, while still compiling to efficiently
executable code. We conclude by summarizing the current status of an ongoing language
design and implementation project that is based on this idea.
alternative_title:
- LIPIcs
author:
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Damien
full_name: Zufferey, Damien
id: 4397AC76-F248-11E8-B48F-1D18A9856A87
last_name: Zufferey
orcid: 0000-0002-3197-8736
citation:
ama: Dragoi C, Henzinger TA, Zufferey D. The need for language support for fault-tolerant
distributed systems. 2015;32:90-102. doi:10.4230/LIPIcs.SNAPL.2015.90
apa: 'Dragoi, C., Henzinger, T. A., & Zufferey, D. (2015). The need for language
support for fault-tolerant distributed systems. Presented at the SNAPL: Summit
oN Advances in Programming Languages, Asilomar, CA, United States: Schloss Dagstuhl
- Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SNAPL.2015.90'
chicago: Dragoi, Cezara, Thomas A Henzinger, and Damien Zufferey. “The Need for
Language Support for Fault-Tolerant Distributed Systems.” Leibniz International
Proceedings in Informatics. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2015. https://doi.org/10.4230/LIPIcs.SNAPL.2015.90.
ieee: C. Dragoi, T. A. Henzinger, and D. Zufferey, “The need for language support
for fault-tolerant distributed systems,” vol. 32. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, pp. 90–102, 2015.
ista: Dragoi C, Henzinger TA, Zufferey D. 2015. The need for language support for
fault-tolerant distributed systems. 32, 90–102.
mla: Dragoi, Cezara, et al. The Need for Language Support for Fault-Tolerant
Distributed Systems. Vol. 32, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2015, pp. 90–102, doi:10.4230/LIPIcs.SNAPL.2015.90.
short: C. Dragoi, T.A. Henzinger, D. Zufferey, 32 (2015) 90–102.
conference:
end_date: 2015-05-06
location: Asilomar, CA, United States
name: 'SNAPL: Summit oN Advances in Programming Languages'
start_date: 2015-05-03
date_created: 2018-12-11T11:52:22Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2020-08-11T10:09:14Z
day: '01'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.SNAPL.2015.90
ec_funded: 1
file:
- access_level: open_access
checksum: cf5e94baa89a2dc4c5de01abc676eda8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:02Z
date_updated: 2020-07-14T12:44:58Z
file_id: '5050'
file_name: IST-2016-499-v1+1_9.pdf
file_size: 489362
relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: ' 32'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 90 - 102
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication_identifier:
isbn:
- '978-3-939897-80-4 '
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5681'
pubrep_id: '499'
quality_controlled: '1'
scopus_import: 1
series_title: Leibniz International Proceedings in Informatics
status: public
title: The need for language support for fault-tolerant distributed systems
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2015'
...
---
_id: '1497'
abstract:
- lang: eng
text: Detecting allelic biases from high-throughput sequencing data requires an
approach that maximises sensitivity while minimizing false positives. Here, we
present Allelome.PRO, an automated user-friendly bioinformatics pipeline, which
uses high-throughput sequencing data from reciprocal crosses of two genetically
distinct mouse strains to detect allele-specific expression and chromatin modifications.
Allelome.PRO extends approaches used in previous studies that exclusively analyzed
imprinted expression to give a complete picture of the ‘allelome’ by automatically
categorising the allelic expression of all genes in a given cell type into imprinted,
strain-biased, biallelic or non-informative. Allelome.PRO offers increased sensitivity
to analyze lowly expressed transcripts, together with a robust false discovery
rate empirically calculated from variation in the sequencing data. We used RNA-seq
data from mouse embryonic fibroblasts from F1 reciprocal crosses to determine
a biologically relevant allelic ratio cutoff, and define for the first time an
entire allelome. Furthermore, we show that Allelome.PRO detects differential enrichment
of H3K4me3 over promoters from ChIP-seq data validating the RNA-seq results. This
approach can be easily extended to analyze histone marks of active enhancers,
or transcription factor binding sites and therefore provides a powerful tool to
identify candidate cis regulatory elements genome wide.
acknowledgement: "Austrian Science Fund [FWF P25185-B22, FWF F4302- B09, FWFW1207-B09].
Funding for open access charge: Austrian Science Fund.\r\nWe thank Florian Breitwieser
for advice during the early stages of this project. High-throughput sequencing was
conducted by the Biomedical Sequencing Facility (BSF) at CeMM in Vienna."
article_number: e146
author:
- first_name: Daniel
full_name: Andergassen, Daniel
last_name: Andergassen
- first_name: Christoph
full_name: Dotter, Christoph
id: 4C66542E-F248-11E8-B48F-1D18A9856A87
last_name: Dotter
- first_name: Tomasz
full_name: Kulinski, Tomasz
last_name: Kulinski
- first_name: Philipp
full_name: Guenzl, Philipp
last_name: Guenzl
- first_name: Philipp
full_name: Bammer, Philipp
last_name: Bammer
- first_name: Denise
full_name: Barlow, Denise
last_name: Barlow
- first_name: Florian
full_name: Pauler, Florian
last_name: Pauler
- first_name: Quanah
full_name: Hudson, Quanah
last_name: Hudson
citation:
ama: Andergassen D, Dotter C, Kulinski T, et al. Allelome.PRO, a pipeline to define
allele-specific genomic features from high-throughput sequencing data. Nucleic
Acids Research. 2015;43(21). doi:10.1093/nar/gkv727
apa: Andergassen, D., Dotter, C., Kulinski, T., Guenzl, P., Bammer, P., Barlow,
D., … Hudson, Q. (2015). Allelome.PRO, a pipeline to define allele-specific genomic
features from high-throughput sequencing data. Nucleic Acids Research.
Oxford University Press. https://doi.org/10.1093/nar/gkv727
chicago: Andergassen, Daniel, Christoph Dotter, Tomasz Kulinski, Philipp Guenzl,
Philipp Bammer, Denise Barlow, Florian Pauler, and Quanah Hudson. “Allelome.PRO,
a Pipeline to Define Allele-Specific Genomic Features from High-Throughput Sequencing
Data.” Nucleic Acids Research. Oxford University Press, 2015. https://doi.org/10.1093/nar/gkv727.
ieee: D. Andergassen et al., “Allelome.PRO, a pipeline to define allele-specific
genomic features from high-throughput sequencing data,” Nucleic Acids Research,
vol. 43, no. 21. Oxford University Press, 2015.
ista: Andergassen D, Dotter C, Kulinski T, Guenzl P, Bammer P, Barlow D, Pauler
F, Hudson Q. 2015. Allelome.PRO, a pipeline to define allele-specific genomic
features from high-throughput sequencing data. Nucleic Acids Research. 43(21),
e146.
mla: Andergassen, Daniel, et al. “Allelome.PRO, a Pipeline to Define Allele-Specific
Genomic Features from High-Throughput Sequencing Data.” Nucleic Acids Research,
vol. 43, no. 21, e146, Oxford University Press, 2015, doi:10.1093/nar/gkv727.
short: D. Andergassen, C. Dotter, T. Kulinski, P. Guenzl, P. Bammer, D. Barlow,
F. Pauler, Q. Hudson, Nucleic Acids Research 43 (2015).
date_created: 2018-12-11T11:52:22Z
date_published: 2015-07-21T00:00:00Z
date_updated: 2021-01-12T06:51:09Z
day: '21'
ddc:
- '570'
department:
- _id: GaNo
doi: 10.1093/nar/gkv727
file:
- access_level: open_access
checksum: 385b83854fd0eb2e4f386867da2823e2
content_type: application/pdf
creator: dernst
date_created: 2018-12-20T14:18:57Z
date_updated: 2020-07-14T12:44:58Z
file_id: '5768'
file_name: 2015_NucleicAcidsRes_Andergassen.pdf
file_size: 6863297
relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: ' 43'
issue: '21'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Nucleic Acids Research
publication_status: published
publisher: Oxford University Press
publist_id: '5682'
quality_controlled: '1'
scopus_import: 1
status: public
title: Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput
sequencing data
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2015'
...
---
_id: '1499'
abstract:
- lang: eng
text: "We consider weighted automata with both positive and negative integer weights
on edges and\r\nstudy the problem of synchronization using adaptive strategies
that may only observe whether\r\nthe current weight-level is negative or nonnegative.
We show that the synchronization problem is decidable in polynomial time for deterministic
weighted automata."
acknowledgement: "The research leading to these results has received funding from
the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement
601148 (CASSTING), EU FP7 FET project SENSATION, Sino-Danish Basic Research Center
IDAE4CPS, the European Research Council (ERC) under grant agreement 267989 (QUAREM),
the Austrian Science Fund (FWF) project S11402-N23 (RiSE) and Z211-N23 (Wittgenstein
Award), the Czech Science Foundation under grant agreement P202/12/G061, and People
Programme (Marie Curie Actions) of the European Union’s Seventh Framework\r\nProgramme
(FP7/2007-2013) REA Grant No 291734."
alternative_title:
- LIPIcs
author:
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Kim
full_name: Larsen, Kim
last_name: Larsen
- first_name: Simon
full_name: Laursen, Simon
last_name: Laursen
- first_name: Jiří
full_name: Srba, Jiří
last_name: Srba
citation:
ama: 'Kretinsky J, Larsen K, Laursen S, Srba J. Polynomial time decidability of
weighted synchronization under partial observability. In: Vol 42. Schloss Dagstuhl
- Leibniz-Zentrum für Informatik; 2015:142-154. doi:10.4230/LIPIcs.CONCUR.2015.142'
apa: 'Kretinsky, J., Larsen, K., Laursen, S., & Srba, J. (2015). Polynomial
time decidability of weighted synchronization under partial observability (Vol.
42, pp. 142–154). Presented at the CONCUR: Concurrency Theory, Madrid, Spain:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.CONCUR.2015.142'
chicago: Kretinsky, Jan, Kim Larsen, Simon Laursen, and Jiří Srba. “Polynomial Time
Decidability of Weighted Synchronization under Partial Observability,” 42:142–54.
Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. https://doi.org/10.4230/LIPIcs.CONCUR.2015.142.
ieee: 'J. Kretinsky, K. Larsen, S. Laursen, and J. Srba, “Polynomial time decidability
of weighted synchronization under partial observability,” presented at the CONCUR:
Concurrency Theory, Madrid, Spain, 2015, vol. 42, pp. 142–154.'
ista: 'Kretinsky J, Larsen K, Laursen S, Srba J. 2015. Polynomial time decidability
of weighted synchronization under partial observability. CONCUR: Concurrency Theory,
LIPIcs, vol. 42, 142–154.'
mla: Kretinsky, Jan, et al. Polynomial Time Decidability of Weighted Synchronization
under Partial Observability. Vol. 42, Schloss Dagstuhl - Leibniz-Zentrum für
Informatik, 2015, pp. 142–54, doi:10.4230/LIPIcs.CONCUR.2015.142.
short: J. Kretinsky, K. Larsen, S. Laursen, J. Srba, in:, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2015, pp. 142–154.
conference:
end_date: 2015-09-04
location: Madrid, Spain
name: 'CONCUR: Concurrency Theory'
start_date: 2015-09-01
date_created: 2018-12-11T11:52:22Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:51:10Z
day: '01'
ddc:
- '000'
- '003'
department:
- _id: ToHe
- _id: KrCh
doi: 10.4230/LIPIcs.CONCUR.2015.142
ec_funded: 1
file:
- access_level: open_access
checksum: 49eb5021caafaabe5356c65b9c5f8c9c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:12Z
date_updated: 2020-07-14T12:44:58Z
file_id: '4672'
file_name: IST-2016-498-v1+1_32.pdf
file_size: 623563
relation: main_file
file_date_updated: 2020-07-14T12:44:58Z
has_accepted_license: '1'
intvolume: ' 42'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 142 - 154
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5680'
pubrep_id: '498'
quality_controlled: '1'
scopus_import: 1
status: public
title: Polynomial time decidability of weighted synchronization under partial observability
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2015'
...
---
_id: '1495'
abstract:
- lang: eng
text: 'Motivated by biological questions, we study configurations of equal-sized
disks in the Euclidean plane that neither pack nor cover. Measuring the quality
by the probability that a random point lies in exactly one disk, we show that
the regular hexagonal grid gives the maximum among lattice configurations. '
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Mabel
full_name: Iglesias Ham, Mabel
id: 41B58C0C-F248-11E8-B48F-1D18A9856A87
last_name: Iglesias Ham
- first_name: Vitaliy
full_name: Kurlin, Vitaliy
last_name: Kurlin
citation:
ama: 'Edelsbrunner H, Iglesias Ham M, Kurlin V. Relaxed disk packing. In: Proceedings
of the 27th Canadian Conference on Computational Geometry. Vol 2015-August.
Queen’s University; 2015:128-135.'
apa: 'Edelsbrunner, H., Iglesias Ham, M., & Kurlin, V. (2015). Relaxed disk
packing. In Proceedings of the 27th Canadian Conference on Computational Geometry
(Vol. 2015–August, pp. 128–135). Ontario, Canada: Queen’s University.'
chicago: Edelsbrunner, Herbert, Mabel Iglesias Ham, and Vitaliy Kurlin. “Relaxed
Disk Packing.” In Proceedings of the 27th Canadian Conference on Computational
Geometry, 2015–August:128–35. Queen’s University, 2015.
ieee: H. Edelsbrunner, M. Iglesias Ham, and V. Kurlin, “Relaxed disk packing,” in
Proceedings of the 27th Canadian Conference on Computational Geometry,
Ontario, Canada, 2015, vol. 2015–August, pp. 128–135.
ista: 'Edelsbrunner H, Iglesias Ham M, Kurlin V. 2015. Relaxed disk packing. Proceedings
of the 27th Canadian Conference on Computational Geometry. CCCG: Canadian Conference
on Computational Geometry vol. 2015–August, 128–135.'
mla: Edelsbrunner, Herbert, et al. “Relaxed Disk Packing.” Proceedings of the
27th Canadian Conference on Computational Geometry, vol. 2015–August, Queen’s
University, 2015, pp. 128–35.
short: H. Edelsbrunner, M. Iglesias Ham, V. Kurlin, in:, Proceedings of the 27th
Canadian Conference on Computational Geometry, Queen’s University, 2015, pp. 128–135.
conference:
end_date: 2015-08-12
location: Ontario, Canada
name: 'CCCG: Canadian Conference on Computational Geometry'
start_date: 2015-08-10
date_created: 2018-12-11T11:52:21Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:09Z
day: '01'
department:
- _id: HeEd
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1505.03402
month: '08'
oa: 1
oa_version: Submitted Version
page: 128-135
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: Proceedings of the 27th Canadian Conference on Computational Geometry
publication_status: published
publisher: Queen's University
publist_id: '5684'
quality_controlled: '1'
scopus_import: 1
status: public
title: Relaxed disk packing
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2015-August
year: '2015'
...
---
_id: '1504'
abstract:
- lang: eng
text: Let Q = (Q1, . . . , Qn) be a random vector drawn from the uniform distribution
on the set of all n! permutations of {1, 2, . . . , n}. Let Z = (Z1, . . . , Zn),
where Zj is the mean zero variance one random variable obtained by centralizing
and normalizing Qj , j = 1, . . . , n. Assume that Xi , i = 1, . . . ,p are i.i.d.
copies of 1/√ p Z and X = Xp,n is the p × n random matrix with Xi as its ith row.
Then Sn = XX is called the p × n Spearman's rank correlation matrix which can
be regarded as a high dimensional extension of the classical nonparametric statistic
Spearman's rank correlation coefficient between two independent random variables.
In this paper, we establish a CLT for the linear spectral statistics of this nonparametric
random matrix model in the scenario of high dimension, namely, p = p(n) and p/n→c
∈ (0,∞) as n→∞.We propose a novel evaluation scheme to estimate the core quantity
in Anderson and Zeitouni's cumulant method in [Ann. Statist. 36 (2008) 2553-2576]
to bypass the so-called joint cumulant summability. In addition, we raise a two-step
comparison approach to obtain the explicit formulae for the mean and covariance
functions in the CLT. Relying on this CLT, we then construct a distribution-free
statistic to test complete independence for components of random vectors. Owing
to the nonparametric property, we can use this test on generally distributed random
variables including the heavy-tailed ones.
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: Liang
full_name: Lin, Liang
last_name: Lin
- first_name: Guangming
full_name: Pan, Guangming
last_name: Pan
- first_name: Wang
full_name: Zhou, Wang
last_name: Zhou
citation:
ama: Bao Z, Lin L, Pan G, Zhou W. Spectral statistics of large dimensional spearman
s rank correlation matrix and its application. Annals of Statistics. 2015;43(6):2588-2623.
doi:10.1214/15-AOS1353
apa: Bao, Z., Lin, L., Pan, G., & Zhou, W. (2015). Spectral statistics of large
dimensional spearman s rank correlation matrix and its application. Annals
of Statistics. Institute of Mathematical Statistics. https://doi.org/10.1214/15-AOS1353
chicago: Bao, Zhigang, Liang Lin, Guangming Pan, and Wang Zhou. “Spectral Statistics
of Large Dimensional Spearman s Rank Correlation Matrix and Its Application.”
Annals of Statistics. Institute of Mathematical Statistics, 2015. https://doi.org/10.1214/15-AOS1353.
ieee: Z. Bao, L. Lin, G. Pan, and W. Zhou, “Spectral statistics of large dimensional
spearman s rank correlation matrix and its application,” Annals of Statistics,
vol. 43, no. 6. Institute of Mathematical Statistics, pp. 2588–2623, 2015.
ista: Bao Z, Lin L, Pan G, Zhou W. 2015. Spectral statistics of large dimensional
spearman s rank correlation matrix and its application. Annals of Statistics.
43(6), 2588–2623.
mla: Bao, Zhigang, et al. “Spectral Statistics of Large Dimensional Spearman s Rank
Correlation Matrix and Its Application.” Annals of Statistics, vol. 43,
no. 6, Institute of Mathematical Statistics, 2015, pp. 2588–623, doi:10.1214/15-AOS1353.
short: Z. Bao, L. Lin, G. Pan, W. Zhou, Annals of Statistics 43 (2015) 2588–2623.
date_created: 2018-12-11T11:52:24Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T06:51:14Z
day: '01'
doi: 10.1214/15-AOS1353
extern: '1'
intvolume: ' 43'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1312.5119
month: '12'
oa: 1
oa_version: Published Version
page: 2588 - 2623
publication: Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5674'
quality_controlled: '1'
status: public
title: Spectral statistics of large dimensional spearman s rank correlation matrix
and its application
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2015'
...
---
_id: '1503'
abstract:
- lang: eng
text: A Herman-Avila-Bochi type formula is obtained for the average sum of the top
d Lyapunov exponents over a one-parameter family of double-struck G-cocycles,
where double-struck G is the group that leaves a certain, non-degenerate Hermitian
form of signature (c, d) invariant. The generic example of such a group is the
pseudo-unitary group U(c, d) or, in the case c = d, the Hermitian-symplectic group
HSp(2d) which naturally appears for cocycles related to Schrödinger operators.
In the case d = 1, the formula for HSp(2d) cocycles reduces to the Herman-Avila-Bochi
formula for SL(2, ℝ) cocycles.
author:
- first_name: Christian
full_name: Sadel, Christian
id: 4760E9F8-F248-11E8-B48F-1D18A9856A87
last_name: Sadel
orcid: 0000-0001-8255-3968
citation:
ama: Sadel C. A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
and Hermitian-symplectic-cocycles. Ergodic Theory and Dynamical Systems.
2015;35(5):1582-1591. doi:10.1017/etds.2013.103
apa: Sadel, C. (2015). A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
and Hermitian-symplectic-cocycles. Ergodic Theory and Dynamical Systems.
Cambridge University Press. https://doi.org/10.1017/etds.2013.103
chicago: Sadel, Christian. “A Herman-Avila-Bochi Formula for Higher-Dimensional
Pseudo-Unitary and Hermitian-Symplectic-Cocycles.” Ergodic Theory and Dynamical
Systems. Cambridge University Press, 2015. https://doi.org/10.1017/etds.2013.103.
ieee: C. Sadel, “A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
and Hermitian-symplectic-cocycles,” Ergodic Theory and Dynamical Systems,
vol. 35, no. 5. Cambridge University Press, pp. 1582–1591, 2015.
ista: Sadel C. 2015. A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary
and Hermitian-symplectic-cocycles. Ergodic Theory and Dynamical Systems. 35(5),
1582–1591.
mla: Sadel, Christian. “A Herman-Avila-Bochi Formula for Higher-Dimensional Pseudo-Unitary
and Hermitian-Symplectic-Cocycles.” Ergodic Theory and Dynamical Systems,
vol. 35, no. 5, Cambridge University Press, 2015, pp. 1582–91, doi:10.1017/etds.2013.103.
short: C. Sadel, Ergodic Theory and Dynamical Systems 35 (2015) 1582–1591.
date_created: 2018-12-11T11:52:24Z
date_published: 2015-03-14T00:00:00Z
date_updated: 2021-01-12T06:51:13Z
day: '14'
doi: 10.1017/etds.2013.103
extern: '1'
intvolume: ' 35'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1307.8414
month: '03'
oa: 1
oa_version: Preprint
page: 1582 - 1591
publication: Ergodic Theory and Dynamical Systems
publication_status: published
publisher: Cambridge University Press
publist_id: '5675'
quality_controlled: '1'
status: public
title: A Herman-Avila-Bochi formula for higher-dimensional pseudo-unitary and Hermitian-symplectic-cocycles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2015'
...
---
_id: '1510'
abstract:
- lang: eng
text: 'The concept of well group in a special but important case captures homological
properties of the zero set of a continuous map f from K to R^n on a compact space
K that are invariant with respect to perturbations of f. The perturbations are
arbitrary continuous maps within L_infty distance r from f for a given r >
0. The main drawback of the approach is that the computability of well groups
was shown only when dim K = n or n = 1. Our contribution to the theory of well
groups is twofold: on the one hand we improve on the computability issue, but
on the other hand we present a range of examples where the well groups are incomplete
invariants, that is, fail to capture certain important robust properties of the
zero set. For the first part, we identify a computable subgroup of the well group
that is obtained by cap product with the pullback of the orientation of R^n by
f. In other words, well groups can be algorithmically approximated from below.
When f is smooth and dim K < 2n-2, our approximation of the (dim K-n)th well
group is exact. For the second part, we find examples of maps f, f'' from K to
R^n with all well groups isomorphic but whose perturbations have different zero
sets. We discuss on a possible replacement of the well groups of vector valued
maps by an invariant of a better descriptive power and computability status. '
alternative_title:
- LIPIcs
author:
- first_name: Peter
full_name: Franek, Peter
id: 473294AE-F248-11E8-B48F-1D18A9856A87
last_name: Franek
- first_name: Marek
full_name: Krcál, Marek
id: 33E21118-F248-11E8-B48F-1D18A9856A87
last_name: Krcál
citation:
ama: 'Franek P, Krcál M. On computability and triviality of well groups. In: Vol
34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:842-856. doi:10.4230/LIPIcs.SOCG.2015.842'
apa: 'Franek, P., & Krcál, M. (2015). On computability and triviality of well
groups (Vol. 34, pp. 842–856). Presented at the SoCG: Symposium on Computational
Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
https://doi.org/10.4230/LIPIcs.SOCG.2015.842'
chicago: Franek, Peter, and Marek Krcál. “On Computability and Triviality of Well
Groups,” 34:842–56. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. https://doi.org/10.4230/LIPIcs.SOCG.2015.842.
ieee: 'P. Franek and M. Krcál, “On computability and triviality of well groups,”
presented at the SoCG: Symposium on Computational Geometry, Eindhoven, Netherlands,
2015, vol. 34, pp. 842–856.'
ista: 'Franek P, Krcál M. 2015. On computability and triviality of well groups.
SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 842–856.'
mla: Franek, Peter, and Marek Krcál. On Computability and Triviality of Well
Groups. Vol. 34, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015,
pp. 842–56, doi:10.4230/LIPIcs.SOCG.2015.842.
short: P. Franek, M. Krcál, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2015, pp. 842–856.
conference:
end_date: 2015-06-25
location: Eindhoven, Netherlands
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2015-06-22
date_created: 2018-12-11T11:52:26Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2023-02-21T17:02:57Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
- _id: HeEd
doi: 10.4230/LIPIcs.SOCG.2015.842
ec_funded: 1
file:
- access_level: open_access
checksum: 49eb5021caafaabe5356c65b9c5f8c9c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:19Z
date_updated: 2020-07-14T12:44:59Z
file_id: '5001'
file_name: IST-2016-503-v1+1_32.pdf
file_size: 623563
relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
intvolume: ' 34'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 842 - 856
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5667'
pubrep_id: '503'
quality_controlled: '1'
related_material:
record:
- id: '1408'
relation: later_version
status: public
scopus_import: 1
status: public
title: On computability and triviality of well groups
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1505'
abstract:
- lang: eng
text: This paper is aimed at deriving the universality of the largest eigenvalue
of a class of high-dimensional real or complex sample covariance matrices of the
form W N =Σ 1/2XX∗Σ 1/2 . Here, X = (xij )M,N is an M× N random matrix with independent
entries xij , 1 ≤ i M,≤ 1 ≤ j ≤ N such that Exij = 0, E|xij |2 = 1/N . On dimensionality,
we assume that M = M(N) and N/M → d ε (0, ∞) as N ∞→. For a class of general deterministic
positive-definite M × M matrices Σ , under some additional assumptions on the
distribution of xij 's, we show that the limiting behavior of the largest eigenvalue
of W N is universal, via pursuing a Green function comparison strategy raised
in [Probab. Theory Related Fields 154 (2012) 341-407, Adv. Math. 229 (2012) 1435-1515]
by Erd″os, Yau and Yin for Wigner matrices and extended by Pillai and Yin [Ann.
Appl. Probab. 24 (2014) 935-1001] to sample covariance matrices in the null case
(&Epsi = I ). Consequently, in the standard complex case (Ex2 ij = 0), combing
this universality property and the results known for Gaussian matrices obtained
by El Karoui in [Ann. Probab. 35 (2007) 663-714] (nonsingular case) and Onatski
in [Ann. Appl. Probab. 18 (2008) 470-490] (singular case), we show that after
an appropriate normalization the largest eigenvalue of W N converges weakly to
the type 2 Tracy-Widom distribution TW2 . Moreover, in the real case, we show
that whenΣ is spiked with a fixed number of subcritical spikes, the type 1 Tracy-Widom
limit TW1 holds for the normalized largest eigenvalue of W N , which extends a
result of Féral and Péché in [J. Math. Phys. 50 (2009) 073302] to the scenario
of nondiagonal Σ and more generally distributed X . In summary, we establish the
Tracy-Widom type universality for the largest eigenvalue of generally distributed
sample covariance matrices under quite light assumptions on &Sigma . Applications
of these limiting results to statistical signal detection and structure recognition
of separable covariance matrices are also discussed.
acknowledgement: "B.Z. was supported in part by NSFC Grant 11071213, ZJNSF
\ Grant R6090034 and SRFDP Grant 20100101110001. P.G. was supported in part
by the Ministry of Education, Singapore, under Grant ARC 14/11. Z.W. was supported
\ in part by the Ministry of Education, Singapore, under Grant ARC 14/11,
\ and by a Grant R-155-000-131-112 at the National University of Singapore\r\n"
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: Guangming
full_name: Pan, Guangming
last_name: Pan
- first_name: Wang
full_name: Zhou, Wang
last_name: Zhou
citation:
ama: Bao Z, Pan G, Zhou W. Universality for the largest eigenvalue of sample covariance
matrices with general population. Annals of Statistics. 2015;43(1):382-421.
doi:10.1214/14-AOS1281
apa: Bao, Z., Pan, G., & Zhou, W. (2015). Universality for the largest eigenvalue
of sample covariance matrices with general population. Annals of Statistics.
Institute of Mathematical Statistics. https://doi.org/10.1214/14-AOS1281
chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “Universality for the Largest
Eigenvalue of Sample Covariance Matrices with General Population.” Annals of
Statistics. Institute of Mathematical Statistics, 2015. https://doi.org/10.1214/14-AOS1281.
ieee: Z. Bao, G. Pan, and W. Zhou, “Universality for the largest eigenvalue of sample
covariance matrices with general population,” Annals of Statistics, vol.
43, no. 1. Institute of Mathematical Statistics, pp. 382–421, 2015.
ista: Bao Z, Pan G, Zhou W. 2015. Universality for the largest eigenvalue of sample
covariance matrices with general population. Annals of Statistics. 43(1), 382–421.
mla: Bao, Zhigang, et al. “Universality for the Largest Eigenvalue of Sample Covariance
Matrices with General Population.” Annals of Statistics, vol. 43, no. 1,
Institute of Mathematical Statistics, 2015, pp. 382–421, doi:10.1214/14-AOS1281.
short: Z. Bao, G. Pan, W. Zhou, Annals of Statistics 43 (2015) 382–421.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:14Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/14-AOS1281
intvolume: ' 43'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1304.5690
month: '02'
oa: 1
oa_version: Preprint
page: 382 - 421
publication: Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5672'
quality_controlled: '1'
status: public
title: Universality for the largest eigenvalue of sample covariance matrices with
general population
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2015'
...
---
_id: '1508'
abstract:
- lang: eng
text: We consider generalized Wigner ensembles and general β-ensembles with analytic
potentials for any β ≥ 1. The recent universality results in particular assert
that the local averages of consecutive eigenvalue gaps in the bulk of the spectrum
are universal in the sense that they coincide with those of the corresponding
Gaussian β-ensembles. In this article, we show that local averaging is not necessary
for this result, i.e. we prove that the single gap distributions in the bulk are
universal. In fact, with an additional step, our result can be extended to any
C4(ℝ) potential.
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Horng
full_name: Yau, Horng
last_name: Yau
citation:
ama: Erdös L, Yau H. Gap universality of generalized Wigner and β ensembles. Journal
of the European Mathematical Society. 2015;17(8):1927-2036. doi:10.4171/JEMS/548
apa: Erdös, L., & Yau, H. (2015). Gap universality of generalized Wigner and
β ensembles. Journal of the European Mathematical Society. European Mathematical
Society. https://doi.org/10.4171/JEMS/548
chicago: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and
β Ensembles.” Journal of the European Mathematical Society. European Mathematical
Society, 2015. https://doi.org/10.4171/JEMS/548.
ieee: L. Erdös and H. Yau, “Gap universality of generalized Wigner and β ensembles,”
Journal of the European Mathematical Society, vol. 17, no. 8. European
Mathematical Society, pp. 1927–2036, 2015.
ista: Erdös L, Yau H. 2015. Gap universality of generalized Wigner and β ensembles.
Journal of the European Mathematical Society. 17(8), 1927–2036.
mla: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and β
Ensembles.” Journal of the European Mathematical Society, vol. 17, no.
8, European Mathematical Society, 2015, pp. 1927–2036, doi:10.4171/JEMS/548.
short: L. Erdös, H. Yau, Journal of the European Mathematical Society 17 (2015)
1927–2036.
date_created: 2018-12-11T11:52:26Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:15Z
day: '01'
department:
- _id: LaEr
doi: 10.4171/JEMS/548
intvolume: ' 17'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1211.3786
month: '08'
oa: 1
oa_version: Preprint
page: 1927 - 2036
publication: Journal of the European Mathematical Society
publication_status: published
publisher: European Mathematical Society
publist_id: '5669'
quality_controlled: '1'
scopus_import: 1
status: public
title: Gap universality of generalized Wigner and β ensembles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2015'
...
---
_id: '1506'
abstract:
- lang: eng
text: Consider the square random matrix An = (aij)n,n, where {aij:= a(n)ij , i,
j = 1, . . . , n} is a collection of independent real random variables with means
zero and variances one. Under the additional moment condition supn max1≤i,j ≤n
Ea4ij <∞, we prove Girko's logarithmic law of det An in the sense that as n→∞
log | detAn| ? (1/2) log(n-1)! d/→√(1/2) log n N(0, 1).
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: Guangming
full_name: Pan, Guangming
last_name: Pan
- first_name: Wang
full_name: Zhou, Wang
last_name: Zhou
citation:
ama: Bao Z, Pan G, Zhou W. The logarithmic law of random determinant. Bernoulli.
2015;21(3):1600-1628. doi:10.3150/14-BEJ615
apa: Bao, Z., Pan, G., & Zhou, W. (2015). The logarithmic law of random determinant.
Bernoulli. Bernoulli Society for Mathematical Statistics and Probability.
https://doi.org/10.3150/14-BEJ615
chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “The Logarithmic Law of Random
Determinant.” Bernoulli. Bernoulli Society for Mathematical Statistics
and Probability, 2015. https://doi.org/10.3150/14-BEJ615.
ieee: Z. Bao, G. Pan, and W. Zhou, “The logarithmic law of random determinant,”
Bernoulli, vol. 21, no. 3. Bernoulli Society for Mathematical Statistics
and Probability, pp. 1600–1628, 2015.
ista: Bao Z, Pan G, Zhou W. 2015. The logarithmic law of random determinant. Bernoulli.
21(3), 1600–1628.
mla: Bao, Zhigang, et al. “The Logarithmic Law of Random Determinant.” Bernoulli,
vol. 21, no. 3, Bernoulli Society for Mathematical Statistics and Probability,
2015, pp. 1600–28, doi:10.3150/14-BEJ615.
short: Z. Bao, G. Pan, W. Zhou, Bernoulli 21 (2015) 1600–1628.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:14Z
day: '01'
department:
- _id: LaEr
doi: 10.3150/14-BEJ615
intvolume: ' 21'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1208.5823
month: '08'
oa: 1
oa_version: Preprint
page: 1600 - 1628
publication: Bernoulli
publication_status: published
publisher: Bernoulli Society for Mathematical Statistics and Probability
publist_id: '5671'
quality_controlled: '1'
status: public
title: The logarithmic law of random determinant
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2015'
...
---
_id: '1513'
abstract:
- lang: eng
text: "Insects of the order Hemiptera (true bugs) use a wide range of mechanisms
of sex determination, including genetic sex determination, paternal genome elimination,
and haplodiploidy. Genetic sex determination, the prevalent mode, is generally
controlled by a pair of XY sex chromosomes or by an XX/X0 system, but different
configurations that include additional sex chromosomes are also present. Although
this diversity of sex determining systems has been extensively studied at the
cytogenetic level, only the X chromosome of the model pea aphid Acyrthosiphon
pisum has been analyzed at the genomic level, and little is known about X chromosome
biology in the rest of the order.\r\n\r\nIn this study, we take advantage of published
DNA- and RNA-seq data from three additional Hemiptera species to perform a comparative
analysis of the gene content and expression of the X chromosome throughout this
clade. We find that, despite showing evidence of dosage compensation, the X chromosomes
of these species show female-biased expression, and a deficit of male-biased genes,
in direct contrast to the pea aphid X. We further detect an excess of shared gene
content between these very distant species, suggesting that despite the diversity
of sex determining systems, the same chromosomal element is used as the X throughout
a large portion of the order. "
article_processing_charge: No
author:
- first_name: Arka
full_name: Pal, Arka
id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
last_name: Pal
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: 'Pal A, Vicoso B. The X chromosome of hemipteran insects: Conservation, dosage
compensation and sex-biased expression. Genome Biology and Evolution. 2015;7(12):3259-3268.
doi:10.1093/gbe/evv215'
apa: 'Pal, A., & Vicoso, B. (2015). The X chromosome of hemipteran insects:
Conservation, dosage compensation and sex-biased expression. Genome Biology
and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evv215'
chicago: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects:
Conservation, Dosage Compensation and Sex-Biased Expression.” Genome Biology
and Evolution. Oxford University Press, 2015. https://doi.org/10.1093/gbe/evv215.'
ieee: 'A. Pal and B. Vicoso, “The X chromosome of hemipteran insects: Conservation,
dosage compensation and sex-biased expression,” Genome Biology and Evolution,
vol. 7, no. 12. Oxford University Press, pp. 3259–3268, 2015.'
ista: 'Pal A, Vicoso B. 2015. The X chromosome of hemipteran insects: Conservation,
dosage compensation and sex-biased expression. Genome Biology and Evolution. 7(12),
3259–3268.'
mla: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects: Conservation,
Dosage Compensation and Sex-Biased Expression.” Genome Biology and Evolution,
vol. 7, no. 12, Oxford University Press, 2015, pp. 3259–68, doi:10.1093/gbe/evv215.'
short: A. Pal, B. Vicoso, Genome Biology and Evolution 7 (2015) 3259–3268.
date_created: 2018-12-11T11:52:27Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T06:51:18Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evv215
ec_funded: 1
file:
- access_level: open_access
checksum: 2b56b8c2e2a1d4cc3c9cb8daba26dd9b
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:29Z
date_updated: 2020-07-14T12:45:00Z
file_id: '5284'
file_name: IST-2016-496-v1+1_Genome_Biol_Evol-2015-Pal-3259-68.pdf
file_size: 858027
relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: ' 7'
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 3259 - 3268
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '5664'
pubrep_id: '496'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The X chromosome of hemipteran insects: Conservation, dosage compensation
and sex-biased expression'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2015'
...
---
_id: '1517'
abstract:
- lang: eng
text: "We study the large deviation rate functional for the empirical distribution
of independent Brownian particles with drift. In one dimension, it has been shown
by Adams, Dirr, Peletier and Zimmer that this functional is asymptotically equivalent
(in the sense of Γ-convergence) to the Jordan-Kinderlehrer-Otto functional arising
in the Wasserstein gradient flow structure of the Fokker-Planck equation. In higher
dimensions, part of this statement (the lower bound) has been recently proved
by Duong, Laschos and Renger, but the upper bound remained open, since the proof
of Duong et al relies on regularity properties of optimal transport maps that
are restricted to one dimension. In this note we present a new proof of the upper
bound, thereby generalising the result of Adams et al to arbitrary dimensions.\r\n"
article_number: '89'
author:
- first_name: Matthias
full_name: Erbar, Matthias
last_name: Erbar
- first_name: Jan
full_name: Maas, Jan
id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
last_name: Maas
orcid: 0000-0002-0845-1338
- first_name: Michiel
full_name: Renger, Michiel
last_name: Renger
citation:
ama: Erbar M, Maas J, Renger M. From large deviations to Wasserstein gradient flows
in multiple dimensions. Electronic Communications in Probability. 2015;20.
doi:10.1214/ECP.v20-4315
apa: Erbar, M., Maas, J., & Renger, M. (2015). From large deviations to Wasserstein
gradient flows in multiple dimensions. Electronic Communications in Probability.
Institute of Mathematical Statistics. https://doi.org/10.1214/ECP.v20-4315
chicago: Erbar, Matthias, Jan Maas, and Michiel Renger. “From Large Deviations to
Wasserstein Gradient Flows in Multiple Dimensions.” Electronic Communications
in Probability. Institute of Mathematical Statistics, 2015. https://doi.org/10.1214/ECP.v20-4315.
ieee: M. Erbar, J. Maas, and M. Renger, “From large deviations to Wasserstein gradient
flows in multiple dimensions,” Electronic Communications in Probability,
vol. 20. Institute of Mathematical Statistics, 2015.
ista: Erbar M, Maas J, Renger M. 2015. From large deviations to Wasserstein gradient
flows in multiple dimensions. Electronic Communications in Probability. 20, 89.
mla: Erbar, Matthias, et al. “From Large Deviations to Wasserstein Gradient Flows
in Multiple Dimensions.” Electronic Communications in Probability, vol.
20, 89, Institute of Mathematical Statistics, 2015, doi:10.1214/ECP.v20-4315.
short: M. Erbar, J. Maas, M. Renger, Electronic Communications in Probability 20
(2015).
date_created: 2018-12-11T11:52:29Z
date_published: 2015-11-29T00:00:00Z
date_updated: 2021-01-12T06:51:19Z
day: '29'
ddc:
- '519'
department:
- _id: JaMa
doi: 10.1214/ECP.v20-4315
file:
- access_level: open_access
checksum: 135741c17d3e1547ca696b6fbdcd559c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:39Z
date_updated: 2020-07-14T12:45:00Z
file_id: '4828'
file_name: IST-2016-494-v1+1_4315-23820-1-PB.pdf
file_size: 230525
relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: ' 20'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Electronic Communications in Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5660'
pubrep_id: '494'
quality_controlled: '1'
scopus_import: 1
status: public
title: From large deviations to Wasserstein gradient flows in multiple dimensions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2015'
...
---
_id: '1519'
abstract:
- lang: eng
text: Evolutionary biologists have an array of powerful theoretical techniques that
can accurately predict changes in the genetic composition of populations. Changes
in gene frequencies and genetic associations between loci can be tracked as they
respond to a wide variety of evolutionary forces. However, it is often less clear
how to decompose these various forces into components that accurately reflect
the underlying biology. Here, we present several issues that arise in the definition
and interpretation of selection and selection coefficients, focusing on insights
gained through the examination of selection coefficients in multilocus notation.
Using this notation, we discuss how its flexibility-which allows different biological
units to be identified as targets of selection-is reflected in the interpretation
of the coefficients that the notation generates. In many situations, it can be
difficult to agree on whether loci can be considered to be under "direct"
versus "indirect" selection, or to quantify this selection. We present
arguments for what the terms direct and indirect selection might best encompass,
considering a range of issues, from viability and sexual selection to kin selection.
We show how multilocus notation can discriminate between direct and indirect selection,
and describe when it can do so.
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Maria
full_name: Servedio, Maria
last_name: Servedio
citation:
ama: Barton NH, Servedio M. The interpretation of selection coefficients. Evolution.
2015;69(5):1101-1112. doi:10.1111/evo.12641
apa: Barton, N. H., & Servedio, M. (2015). The interpretation of selection coefficients.
Evolution. Wiley. https://doi.org/10.1111/evo.12641
chicago: Barton, Nicholas H, and Maria Servedio. “The Interpretation of Selection
Coefficients.” Evolution. Wiley, 2015. https://doi.org/10.1111/evo.12641.
ieee: N. H. Barton and M. Servedio, “The interpretation of selection coefficients,”
Evolution, vol. 69, no. 5. Wiley, pp. 1101–1112, 2015.
ista: Barton NH, Servedio M. 2015. The interpretation of selection coefficients.
Evolution. 69(5), 1101–1112.
mla: Barton, Nicholas H., and Maria Servedio. “The Interpretation of Selection Coefficients.”
Evolution, vol. 69, no. 5, Wiley, 2015, pp. 1101–12, doi:10.1111/evo.12641.
short: N.H. Barton, M. Servedio, Evolution 69 (2015) 1101–1112.
date_created: 2018-12-11T11:52:29Z
date_published: 2015-03-19T00:00:00Z
date_updated: 2021-01-12T06:51:20Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/evo.12641
ec_funded: 1
file:
- access_level: open_access
checksum: fd8d23f476bc194419929b72ca265c02
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:34Z
date_updated: 2020-07-14T12:45:00Z
file_id: '4822'
file_name: IST-2016-560-v1+1_Interpreting_ML_coefficients_11.2.15_App.pdf
file_size: 188872
relation: main_file
- access_level: open_access
checksum: b774911e70044641d556e258efcb52ef
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:35Z
date_updated: 2020-07-14T12:45:00Z
file_id: '4823'
file_name: IST-2016-560-v1+2_Interpreting_ML_coefficients_11.2.15_mainText.pdf
file_size: 577415
relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: ' 69'
issue: '5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 1101 - 1112
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Evolution
publication_status: published
publisher: Wiley
publist_id: '5656'
pubrep_id: '560'
quality_controlled: '1'
scopus_import: 1
status: public
title: The interpretation of selection coefficients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2015'
...
---
_id: '1525'
abstract:
- lang: eng
text: 'Based on 16 recommendations, efforts should be made to achieve the following
goal: By 2025, all scholarly publication activity in Austria should be Open Access.
In other words, the final versions of all scholarly publications resulting from
the support of public resources must be freely accessible on the Internet without
delay (Gold Open Access). The resources required to meet this obligation shall
be provided to the authors, or the cost of the publication venues shall be borne
directly by the research organisations.'
article_processing_charge: No
article_type: original
author:
- first_name: Bruno
full_name: Bauer, Bruno
last_name: Bauer
- first_name: Guido
full_name: Blechl, Guido
last_name: Blechl
- first_name: Christoph
full_name: Bock, Christoph
last_name: Bock
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
- first_name: Andreas
full_name: Ferus, Andreas
last_name: Ferus
- first_name: Anton
full_name: Graschopf, Anton
last_name: Graschopf
- first_name: Thomas
full_name: König, Thomas
last_name: König
- first_name: Katja
full_name: Mayer, Katja
last_name: Mayer
- first_name: Falk
full_name: Reckling, Falk
last_name: Reckling
- first_name: Katharina
full_name: Rieck, Katharina
last_name: Rieck
- first_name: Peter
full_name: Seitz, Peter
last_name: Seitz
- first_name: Herwig
full_name: Stöger, Herwig
last_name: Stöger
- first_name: Elvira
full_name: Welzig, Elvira
last_name: Welzig
citation:
ama: Bauer B, Blechl G, Bock C, et al. Arbeitsgruppe „Nationale Strategie“ des Open
Access Network Austria OANA. VÖB Mitteilungen. 2015;68(3):580-607. doi:10.5281/zenodo.33178
apa: Bauer, B., Blechl, G., Bock, C., Danowski, P., Ferus, A., Graschopf, A., …
Welzig, E. (2015). Arbeitsgruppe „Nationale Strategie“ des Open Access Network
Austria OANA. VÖB Mitteilungen. Verein Österreichischer Bibliothekare.
https://doi.org/10.5281/zenodo.33178
chicago: Bauer, Bruno, Guido Blechl, Christoph Bock, Patrick Danowski, Andreas Ferus,
Anton Graschopf, Thomas König, et al. “Arbeitsgruppe „Nationale Strategie“ Des
Open Access Network Austria OANA.” VÖB Mitteilungen. Verein Österreichischer
Bibliothekare, 2015. https://doi.org/10.5281/zenodo.33178.
ieee: B. Bauer et al., “Arbeitsgruppe „Nationale Strategie“ des Open Access
Network Austria OANA,” VÖB Mitteilungen, vol. 68, no. 3. Verein Österreichischer
Bibliothekare, pp. 580–607, 2015.
ista: Bauer B, Blechl G, Bock C, Danowski P, Ferus A, Graschopf A, König T, Mayer
K, Reckling F, Rieck K, Seitz P, Stöger H, Welzig E. 2015. Arbeitsgruppe „Nationale
Strategie“ des Open Access Network Austria OANA. VÖB Mitteilungen. 68(3), 580–607.
mla: Bauer, Bruno, et al. “Arbeitsgruppe „Nationale Strategie“ Des Open Access Network
Austria OANA.” VÖB Mitteilungen, vol. 68, no. 3, Verein Österreichischer
Bibliothekare, 2015, pp. 580–607, doi:10.5281/zenodo.33178.
short: B. Bauer, G. Blechl, C. Bock, P. Danowski, A. Ferus, A. Graschopf, T. König,
K. Mayer, F. Reckling, K. Rieck, P. Seitz, H. Stöger, E. Welzig, VÖB Mitteilungen
68 (2015) 580–607.
date_created: 2018-12-11T11:52:31Z
date_published: 2015-11-12T00:00:00Z
date_updated: 2021-01-12T06:51:22Z
day: '12'
ddc:
- '020'
department:
- _id: E-Lib
doi: 10.5281/zenodo.33178
file:
- access_level: open_access
checksum: a495fe253bbc7615b1d60e9e85c94408
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:59Z
date_updated: 2020-07-14T12:45:00Z
file_id: '5317'
file_name: IST-2016-720-v1+1_OANA_OA-Empfehlungen_12-11-2015.pdf
file_size: 931707
relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: ' 68'
issue: '3'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 580 - 607
publication: VÖB Mitteilungen
publication_status: published
publisher: Verein Österreichischer Bibliothekare
publist_id: '5648'
pubrep_id: '720'
quality_controlled: '1'
scopus_import: 1
status: public
title: Arbeitsgruppe „Nationale Strategie“ des Open Access Network Austria OANA
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 68
year: '2015'
...
---
_id: '1539'
abstract:
- lang: eng
text: 'Many stochastic models of biochemical reaction networks contain some chemical
species for which the number of molecules that are present in the system can only
be finite (for instance due to conservation laws), but also other species that
can be present in arbitrarily large amounts. The prime example of such networks
are models of gene expression, which typically contain a small and finite number
of possible states for the promoter but an infinite number of possible states
for the amount of mRNA and protein. One of the main approaches to analyze such
models is through the use of equations for the time evolution of moments of the
chemical species. Recently, a new approach based on conditional moments of the
species with infinite state space given all the different possible states of the
finite species has been proposed. It was argued that this approach allows one
to capture more details about the full underlying probability distribution with
a smaller number of equations. Here, I show that the result that less moments
provide more information can only stem from an unnecessarily complicated description
of the system in the classical formulation. The foundation of this argument will
be the derivation of moment equations that describe the complete probability distribution
over the finite state space but only low-order moments over the infinite state
space. I will show that the number of equations that is needed is always less
than what was previously claimed and always less than the number of conditional
moment equations up to the same order. To support these arguments, a symbolic
algorithm is provided that can be used to derive minimal systems of unconditional
moment equations for models with partially finite state space. '
article_number: '244103'
author:
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
citation:
ama: Ruess J. Minimal moment equations for stochastic models of biochemical reaction
networks with partially finite state space. Journal of Chemical Physics.
2015;143(24). doi:10.1063/1.4937937
apa: Ruess, J. (2015). Minimal moment equations for stochastic models of biochemical
reaction networks with partially finite state space. Journal of Chemical Physics.
American Institute of Physics. https://doi.org/10.1063/1.4937937
chicago: Ruess, Jakob. “Minimal Moment Equations for Stochastic Models of Biochemical
Reaction Networks with Partially Finite State Space.” Journal of Chemical Physics.
American Institute of Physics, 2015. https://doi.org/10.1063/1.4937937.
ieee: J. Ruess, “Minimal moment equations for stochastic models of biochemical reaction
networks with partially finite state space,” Journal of Chemical Physics,
vol. 143, no. 24. American Institute of Physics, 2015.
ista: Ruess J. 2015. Minimal moment equations for stochastic models of biochemical
reaction networks with partially finite state space. Journal of Chemical Physics.
143(24), 244103.
mla: Ruess, Jakob. “Minimal Moment Equations for Stochastic Models of Biochemical
Reaction Networks with Partially Finite State Space.” Journal of Chemical Physics,
vol. 143, no. 24, 244103, American Institute of Physics, 2015, doi:10.1063/1.4937937.
short: J. Ruess, Journal of Chemical Physics 143 (2015).
date_created: 2018-12-11T11:52:36Z
date_published: 2015-12-22T00:00:00Z
date_updated: 2021-01-12T06:51:28Z
day: '22'
ddc:
- '000'
department:
- _id: ToHe
- _id: GaTk
doi: 10.1063/1.4937937
ec_funded: 1
file:
- access_level: open_access
checksum: 838657118ae286463a2b7737319f35ce
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:07:43Z
date_updated: 2020-07-14T12:45:01Z
file_id: '4641'
file_name: IST-2016-593-v1+1_Minimal_moment_equations.pdf
file_size: 605355
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 143'
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Journal of Chemical Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5632'
pubrep_id: '593'
quality_controlled: '1'
scopus_import: 1
status: public
title: Minimal moment equations for stochastic models of biochemical reaction networks
with partially finite state space
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 143
year: '2015'
...
---
_id: '1534'
abstract:
- lang: eng
text: PIN proteins are auxin export carriers that direct intercellular auxin flow
and in turn regulate many aspects of plant growth and development including responses
to environmental changes. The Arabidopsis R2R3-MYB transcription factor FOUR LIPS
(FLP) and its paralogue MYB88 regulate terminal divisions during stomatal development,
as well as female reproductive development and stress responses. Here we show
that FLP and MYB88 act redundantly but differentially in regulating the transcription
of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots. On the
one hand, FLP is involved in responses to gravity stimulation in primary roots,
whereas on the other, FLP and MYB88 function complementarily in establishing the
gravitropic set-point angles of lateral roots. Our results support a model in
which FLP and MYB88 expression specifically determines the temporal-spatial patterns
of PIN3 and PIN7 transcription that are closely associated with their preferential
functions during root responses to gravity.
article_number: '8822'
author:
- first_name: Hongzhe
full_name: Wang, Hongzhe
last_name: Wang
- first_name: Kezhen
full_name: Yang, Kezhen
last_name: Yang
- first_name: Junjie
full_name: Zou, Junjie
last_name: Zou
- first_name: Lingling
full_name: Zhu, Lingling
last_name: Zhu
- first_name: Zidian
full_name: Xie, Zidian
last_name: Xie
- first_name: Miyoterao
full_name: Morita, Miyoterao
last_name: Morita
- first_name: Masao
full_name: Tasaka, Masao
last_name: Tasaka
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Erich
full_name: Grotewold, Erich
last_name: Grotewold
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Fred
full_name: Sack, Fred
last_name: Sack
- first_name: Jie
full_name: Le, Jie
last_name: Le
citation:
ama: Wang H, Yang K, Zou J, et al. Transcriptional regulation of PIN genes by FOUR
LIPS and MYB88 during Arabidopsis root gravitropism. Nature Communications.
2015;6. doi:10.1038/ncomms9822
apa: Wang, H., Yang, K., Zou, J., Zhu, L., Xie, Z., Morita, M., … Le, J. (2015).
Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
root gravitropism. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms9822
chicago: Wang, Hongzhe, Kezhen Yang, Junjie Zou, Lingling Zhu, Zidian Xie, Miyoterao
Morita, Masao Tasaka, et al. “Transcriptional Regulation of PIN Genes by FOUR
LIPS and MYB88 during Arabidopsis Root Gravitropism.” Nature Communications.
Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms9822.
ieee: H. Wang et al., “Transcriptional regulation of PIN genes by FOUR LIPS
and MYB88 during Arabidopsis root gravitropism,” Nature Communications,
vol. 6. Nature Publishing Group, 2015.
ista: Wang H, Yang K, Zou J, Zhu L, Xie Z, Morita M, Tasaka M, Friml J, Grotewold
E, Beeckman T, Vanneste S, Sack F, Le J. 2015. Transcriptional regulation of PIN
genes by FOUR LIPS and MYB88 during Arabidopsis root gravitropism. Nature Communications.
6, 8822.
mla: Wang, Hongzhe, et al. “Transcriptional Regulation of PIN Genes by FOUR LIPS
and MYB88 during Arabidopsis Root Gravitropism.” Nature Communications,
vol. 6, 8822, Nature Publishing Group, 2015, doi:10.1038/ncomms9822.
short: H. Wang, K. Yang, J. Zou, L. Zhu, Z. Xie, M. Morita, M. Tasaka, J. Friml,
E. Grotewold, T. Beeckman, S. Vanneste, F. Sack, J. Le, Nature Communications
6 (2015).
date_created: 2018-12-11T11:52:34Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '18'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1038/ncomms9822
ec_funded: 1
file:
- access_level: open_access
checksum: 3c06735fc7cd7e482ca830cbd26001bf
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:07Z
date_updated: 2020-07-14T12:45:01Z
file_id: '5259'
file_name: IST-2016-485-v1+1_ncomms9822.pdf
file_size: 1852268
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5637'
pubrep_id: '485'
quality_controlled: '1'
scopus_import: 1
status: public
title: Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
root gravitropism
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1538'
abstract:
- lang: eng
text: Systems biology rests on the idea that biological complexity can be better
unraveled through the interplay of modeling and experimentation. However, the
success of this approach depends critically on the informativeness of the chosen
experiments, which is usually unknown a priori. Here, we propose a systematic
scheme based on iterations of optimal experiment design, flow cytometry experiments,
and Bayesian parameter inference to guide the discovery process in the case of
stochastic biochemical reaction networks. To illustrate the benefit of our methodology,
we apply it to the characterization of an engineered light-inducible gene expression
circuit in yeast and compare the performance of the resulting model with models
identified from nonoptimal experiments. In particular, we compare the parameter
posterior distributions and the precision to which the outcome of future experiments
can be predicted. Moreover, we illustrate how the identified stochastic model
can be used to determine light induction patterns that make either the average
amount of protein or the variability in a population of cells follow a desired
profile. Our results show that optimal experiment design allows one to derive
models that are accurate enough to precisely predict and regulate the protein
expression in heterogeneous cell populations over extended periods of time.
acknowledgement: 'J.R., F.P., and J.L. acknowledge support from the European Commission
under the Network of Excellence HYCON2 (highly-complex and networked control systems)
and SystemsX.ch under the SignalX Project. J.R. acknowledges support from the People
Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme
FP7/2007-2013 under REA (Research Executive Agency) Grant 291734. M.K. acknowledges
support from Human Frontier Science Program Grant RP0061/2011 (www.hfsp.org). '
author:
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
- first_name: Francesca
full_name: Parise, Francesca
last_name: Parise
- first_name: Andreas
full_name: Milias Argeitis, Andreas
last_name: Milias Argeitis
- first_name: Mustafa
full_name: Khammash, Mustafa
last_name: Khammash
- first_name: John
full_name: Lygeros, John
last_name: Lygeros
citation:
ama: Ruess J, Parise F, Milias Argeitis A, Khammash M, Lygeros J. Iterative experiment
design guides the characterization of a light-inducible gene expression circuit.
PNAS. 2015;112(26):8148-8153. doi:10.1073/pnas.1423947112
apa: Ruess, J., Parise, F., Milias Argeitis, A., Khammash, M., & Lygeros, J.
(2015). Iterative experiment design guides the characterization of a light-inducible
gene expression circuit. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1423947112
chicago: Ruess, Jakob, Francesca Parise, Andreas Milias Argeitis, Mustafa Khammash,
and John Lygeros. “Iterative Experiment Design Guides the Characterization of
a Light-Inducible Gene Expression Circuit.” PNAS. National Academy of Sciences,
2015. https://doi.org/10.1073/pnas.1423947112.
ieee: J. Ruess, F. Parise, A. Milias Argeitis, M. Khammash, and J. Lygeros, “Iterative
experiment design guides the characterization of a light-inducible gene expression
circuit,” PNAS, vol. 112, no. 26. National Academy of Sciences, pp. 8148–8153,
2015.
ista: Ruess J, Parise F, Milias Argeitis A, Khammash M, Lygeros J. 2015. Iterative
experiment design guides the characterization of a light-inducible gene expression
circuit. PNAS. 112(26), 8148–8153.
mla: Ruess, Jakob, et al. “Iterative Experiment Design Guides the Characterization
of a Light-Inducible Gene Expression Circuit.” PNAS, vol. 112, no. 26,
National Academy of Sciences, 2015, pp. 8148–53, doi:10.1073/pnas.1423947112.
short: J. Ruess, F. Parise, A. Milias Argeitis, M. Khammash, J. Lygeros, PNAS 112
(2015) 8148–8153.
date_created: 2018-12-11T11:52:36Z
date_published: 2015-06-30T00:00:00Z
date_updated: 2021-01-12T06:51:27Z
day: '30'
department:
- _id: ToHe
- _id: GaTk
doi: 10.1073/pnas.1423947112
ec_funded: 1
external_id:
pmid:
- '26085136'
intvolume: ' 112'
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491780/
month: '06'
oa: 1
oa_version: Submitted Version
page: 8148 - 8153
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5633'
quality_controlled: '1'
scopus_import: 1
status: public
title: Iterative experiment design guides the characterization of a light-inducible
gene expression circuit
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1535'
abstract:
- lang: eng
text: Neuronal and neuroendocrine L-type calcium channels (Cav1.2, Cav1.3) open
readily at relatively low membrane potentials and allow Ca2+ to enter the cells
near resting potentials. In this way, Cav1.2 and Cav1.3 shape the action potential
waveform, contribute to gene expression, synaptic plasticity, neuronal differentiation,
hormone secretion and pacemaker activity. In the chromaffin cells (CCs) of the
adrenal medulla, Cav1.3 is highly expressed and is shown to support most of the
pacemaking current that sustains action potential (AP) firings and part of the
catecholamine secretion. Cav1.3 forms Ca2+-nanodomains with the fast inactivating
BK channels and drives the resting SK currents. These latter set the inter-spike
interval duration between consecutive spikes during spontaneous firing and the
rate of spike adaptation during sustained depolarizations. Cav1.3 plays also a
primary role in the switch from “tonic” to “burst” firing that occurs in mouse
CCs when either the availability of voltage-gated Na channels (Nav) is reduced
or the β2 subunit featuring the fast inactivating BK channels is deleted. Here,
we discuss the functional role of these “neuronlike” firing modes in CCs and how
Cav1.3 contributes to them. The open issue is to understand how these novel firing
patterns are adapted to regulate the quantity of circulating catecholamines during
resting condition or in response to acute and chronic stress.
acknowledgement: This work was supported by the Italian MIUR (PRIN 2010/2011 project
2010JFYFY2) and the University of Torino.
article_processing_charge: No
article_type: original
author:
- first_name: David H
full_name: Vandael, David H
id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
last_name: Vandael
orcid: 0000-0001-7577-1676
- first_name: Andrea
full_name: Marcantoni, Andrea
last_name: Marcantoni
- first_name: Emilio
full_name: Carbone, Emilio
last_name: Carbone
citation:
ama: Vandael DH, Marcantoni A, Carbone E. Cav1.3 channels as key regulators of neuron-like
firings and catecholamine release in chromaffin cells. Current Molecular Pharmacology.
2015;8(2):149-161. doi:10.2174/1874467208666150507105443
apa: Vandael, D. H., Marcantoni, A., & Carbone, E. (2015). Cav1.3 channels as
key regulators of neuron-like firings and catecholamine release in chromaffin
cells. Current Molecular Pharmacology. Bentham Science Publishers. https://doi.org/10.2174/1874467208666150507105443
chicago: Vandael, David H, Andrea Marcantoni, and Emilio Carbone. “Cav1.3 Channels
as Key Regulators of Neuron-like Firings and Catecholamine Release in Chromaffin
Cells.” Current Molecular Pharmacology. Bentham Science Publishers, 2015.
https://doi.org/10.2174/1874467208666150507105443.
ieee: D. H. Vandael, A. Marcantoni, and E. Carbone, “Cav1.3 channels as key regulators
of neuron-like firings and catecholamine release in chromaffin cells,” Current
Molecular Pharmacology, vol. 8, no. 2. Bentham Science Publishers, pp. 149–161,
2015.
ista: Vandael DH, Marcantoni A, Carbone E. 2015. Cav1.3 channels as key regulators
of neuron-like firings and catecholamine release in chromaffin cells. Current
Molecular Pharmacology. 8(2), 149–161.
mla: Vandael, David H., et al. “Cav1.3 Channels as Key Regulators of Neuron-like
Firings and Catecholamine Release in Chromaffin Cells.” Current Molecular Pharmacology,
vol. 8, no. 2, Bentham Science Publishers, 2015, pp. 149–61, doi:10.2174/1874467208666150507105443.
short: D.H. Vandael, A. Marcantoni, E. Carbone, Current Molecular Pharmacology 8
(2015) 149–161.
date_created: 2018-12-11T11:52:35Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '01'
department:
- _id: PeJo
doi: 10.2174/1874467208666150507105443
external_id:
pmid:
- '25966692'
intvolume: ' 8'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384372/
month: '10'
oa: 1
oa_version: Submitted Version
page: 149 - 161
pmid: 1
publication: Current Molecular Pharmacology
publication_status: published
publisher: Bentham Science Publishers
publist_id: '5636'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cav1.3 channels as key regulators of neuron-like firings and catecholamine
release in chromaffin cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1542'
abstract:
- lang: eng
text: 'The theory of population genetics and evolutionary computation have been
evolving separately for nearly 30 years. Many results have been independently
obtained in both fields and many others are unique to its respective field. We
aim to bridge this gap by developing a unifying framework for evolutionary processes
that allows both evolutionary algorithms and population genetics models to be
cast in the same formal framework. The framework we present here decomposes the
evolutionary process into its several components in order to facilitate the identification
of similarities between different models. In particular, we propose a classification
of evolutionary operators based on the defining properties of the different components.
We cast several commonly used operators from both fields into this common framework.
Using this, we map different evolutionary and genetic algorithms to different
evolutionary regimes and identify candidates with the most potential for the translation
of results between the fields. This provides a unified description of evolutionary
processes and represents a stepping stone towards new tools and results to both
fields. '
author:
- first_name: Tiago
full_name: Paixao, Tiago
id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
last_name: Paixao
orcid: 0000-0003-2361-3953
- first_name: Golnaz
full_name: Badkobeh, Golnaz
last_name: Badkobeh
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Doğan
full_name: Çörüş, Doğan
last_name: Çörüş
- first_name: Duccuong
full_name: Dang, Duccuong
last_name: Dang
- first_name: Tobias
full_name: Friedrich, Tobias
last_name: Friedrich
- first_name: Per
full_name: Lehre, Per
last_name: Lehre
- first_name: Dirk
full_name: Sudholt, Dirk
last_name: Sudholt
- first_name: Andrew
full_name: Sutton, Andrew
last_name: Sutton
- first_name: Barbora
full_name: Trubenova, Barbora
id: 42302D54-F248-11E8-B48F-1D18A9856A87
last_name: Trubenova
orcid: 0000-0002-6873-2967
citation:
ama: Paixao T, Badkobeh G, Barton NH, et al. Toward a unifying framework for evolutionary
processes. Journal of Theoretical Biology. 2015;383:28-43. doi:10.1016/j.jtbi.2015.07.011
apa: Paixao, T., Badkobeh, G., Barton, N. H., Çörüş, D., Dang, D., Friedrich, T.,
… Trubenova, B. (2015). Toward a unifying framework for evolutionary processes.
Journal of Theoretical Biology. Elsevier. https://doi.org/10.1016/j.jtbi.2015.07.011
chicago: Paixao, Tiago, Golnaz Badkobeh, Nicholas H Barton, Doğan Çörüş, Duccuong
Dang, Tobias Friedrich, Per Lehre, Dirk Sudholt, Andrew Sutton, and Barbora Trubenova.
“Toward a Unifying Framework for Evolutionary Processes.” Journal of Theoretical
Biology. Elsevier, 2015. https://doi.org/10.1016/j.jtbi.2015.07.011.
ieee: T. Paixao et al., “Toward a unifying framework for evolutionary processes,”
Journal of Theoretical Biology, vol. 383. Elsevier, pp. 28–43, 2015.
ista: Paixao T, Badkobeh G, Barton NH, Çörüş D, Dang D, Friedrich T, Lehre P, Sudholt
D, Sutton A, Trubenova B. 2015. Toward a unifying framework for evolutionary processes. Journal
of Theoretical Biology. 383, 28–43.
mla: Paixao, Tiago, et al. “Toward a Unifying Framework for Evolutionary Processes.”
Journal of Theoretical Biology, vol. 383, Elsevier, 2015, pp. 28–43, doi:10.1016/j.jtbi.2015.07.011.
short: T. Paixao, G. Badkobeh, N.H. Barton, D. Çörüş, D. Dang, T. Friedrich, P.
Lehre, D. Sudholt, A. Sutton, B. Trubenova, Journal of Theoretical Biology 383
(2015) 28–43.
date_created: 2018-12-11T11:52:37Z
date_published: 2015-10-21T00:00:00Z
date_updated: 2021-01-12T06:51:29Z
day: '21'
ddc:
- '570'
department:
- _id: NiBa
- _id: CaGu
doi: 10.1016/j.jtbi.2015.07.011
ec_funded: 1
file:
- access_level: open_access
checksum: 33b60ecfea60764756a9ee9df5eb65ca
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:53Z
date_updated: 2020-07-14T12:45:01Z
file_id: '5244'
file_name: IST-2016-483-v1+1_1-s2.0-S0022519315003409-main.pdf
file_size: 595307
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 383'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 28 - 43
project:
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618091'
name: Speed of Adaptation in Population Genetics and Evolutionary Computation
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: ' Journal of Theoretical Biology'
publication_status: published
publisher: Elsevier
publist_id: '5629'
pubrep_id: '483'
quality_controlled: '1'
scopus_import: 1
status: public
title: Toward a unifying framework for evolutionary processes
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 383
year: '2015'
...
---
_id: '1546'
abstract:
- lang: eng
text: Synaptic efficacy and precision are influenced by the coupling of voltage-gated
Ca2+ channels (VGCCs) to vesicles. But because the topography of VGCCs and their
proximity to vesicles is unknown, a quantitative understanding of the determinants
of vesicular release at nanometer scale is lacking. To investigate this, we combined
freeze-fracture replica immunogold labeling of Cav2.1 channels, local [Ca2+] imaging,
and patch pipette perfusion of EGTA at the calyx of Held. Between postnatal day
7 and 21, VGCCs formed variable sized clusters and vesicular release became less
sensitive to EGTA, whereas fixed Ca2+ buffer properties remained constant. Experimentally
constrained reaction-diffusion simulations suggest that Ca2+ sensors for vesicular
release are located at the perimeter of VGCC clusters (<30nm) and predict that
VGCC number per cluster determines vesicular release probability without altering
release time course. This "perimeter release model" provides a unifying
framework accounting for developmental changes in both synaptic efficacy and time
course.
acknowledgement: This work was supported by the Core Research for Evolutional Science
and Technology (CREST) of Japan Science and Technology Agency to T.T. and R.S.;
by the funding provided by Okinawa Institute of Science and Technology (OIST) to
T.T. and Y.N.; by JSPS Core-to-Core Program, A. Advanced Networks to T.T.; by the
Grant-in-Aid for Young Scientists from the Japanese Ministry of Education, Culture,
Sports, Science and Technology (#23700474) to Y.N.; by the Centre National de la
Recherche Scientifique through the Actions Thematiques et Initatives sur Programme,
Fondation Fyssen, Fondation pour la Recherche Medicale, Federation pour la Recherche
sur le Cerveau, Agence Nationale de la Recherche (ANR-2007-Neuro-008-01 and ANR-2010-BLAN-1411-01)
to D.D. and Y.N.; and by the European Commission Coordination Action ENINET (LSHM-CT-2005-19063)
to D.D. and R.A.S. R.A.S. and J.S.R. were funded by Wellcome Trust Senior (064413)
and Principal (095667) Research Fellowship and an ERC advance grant (294667) to
RAS.
author:
- first_name: Yukihiro
full_name: Nakamura, Yukihiro
last_name: Nakamura
- first_name: Harumi
full_name: Harada, Harumi
id: 2E55CDF2-F248-11E8-B48F-1D18A9856A87
last_name: Harada
orcid: 0000-0001-7429-7896
- first_name: Naomi
full_name: Kamasawa, Naomi
last_name: Kamasawa
- first_name: Ko
full_name: Matsui, Ko
last_name: Matsui
- first_name: Jason
full_name: Rothman, Jason
last_name: Rothman
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: R Angus
full_name: Silver, R Angus
last_name: Silver
- first_name: David
full_name: Digregorio, David
last_name: Digregorio
- first_name: Tomoyuki
full_name: Takahashi, Tomoyuki
last_name: Takahashi
citation:
ama: Nakamura Y, Harada H, Kamasawa N, et al. Nanoscale distribution of presynaptic
Ca2+ channels and its impact on vesicular release during development. Neuron.
2015;85(1):145-158. doi:10.1016/j.neuron.2014.11.019
apa: Nakamura, Y., Harada, H., Kamasawa, N., Matsui, K., Rothman, J., Shigemoto,
R., … Takahashi, T. (2015). Nanoscale distribution of presynaptic Ca2+ channels
and its impact on vesicular release during development. Neuron. Elsevier.
https://doi.org/10.1016/j.neuron.2014.11.019
chicago: Nakamura, Yukihiro, Harumi Harada, Naomi Kamasawa, Ko Matsui, Jason Rothman,
Ryuichi Shigemoto, R Angus Silver, David Digregorio, and Tomoyuki Takahashi. “Nanoscale
Distribution of Presynaptic Ca2+ Channels and Its Impact on Vesicular Release
during Development.” Neuron. Elsevier, 2015. https://doi.org/10.1016/j.neuron.2014.11.019.
ieee: Y. Nakamura et al., “Nanoscale distribution of presynaptic Ca2+ channels
and its impact on vesicular release during development,” Neuron, vol. 85,
no. 1. Elsevier, pp. 145–158, 2015.
ista: Nakamura Y, Harada H, Kamasawa N, Matsui K, Rothman J, Shigemoto R, Silver
RA, Digregorio D, Takahashi T. 2015. Nanoscale distribution of presynaptic Ca2+
channels and its impact on vesicular release during development. Neuron. 85(1),
145–158.
mla: Nakamura, Yukihiro, et al. “Nanoscale Distribution of Presynaptic Ca2+ Channels
and Its Impact on Vesicular Release during Development.” Neuron, vol. 85,
no. 1, Elsevier, 2015, pp. 145–58, doi:10.1016/j.neuron.2014.11.019.
short: Y. Nakamura, H. Harada, N. Kamasawa, K. Matsui, J. Rothman, R. Shigemoto,
R.A. Silver, D. Digregorio, T. Takahashi, Neuron 85 (2015) 145–158.
date_created: 2018-12-11T11:52:39Z
date_published: 2015-01-07T00:00:00Z
date_updated: 2021-01-12T06:51:31Z
day: '07'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1016/j.neuron.2014.11.019
file:
- access_level: open_access
checksum: 725f4d5be2dbb44b283ce722645ef37d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:47Z
date_updated: 2020-07-14T12:45:01Z
file_id: '5170'
file_name: IST-2016-482-v1+1_1-s2.0-S0896627314010472-main.pdf
file_size: 3080111
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 85'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 145 - 158
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5625'
pubrep_id: '482'
quality_controlled: '1'
scopus_import: 1
status: public
title: Nanoscale distribution of presynaptic Ca2+ channels and its impact on vesicular
release during development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 85
year: '2015'
...
---
_id: '1544'
abstract:
- lang: eng
text: 'Cell division in prokaryotes and eukaryotes is commonly initiated by the
well-controlled binding of proteins to the cytoplasmic side of the cell membrane.
However, a precise characterization of the spatiotemporal dynamics of membrane-bound
proteins is often difficult to achieve in vivo. Here, we present protocols for
the use of supported lipid bilayers to rebuild the cytokinetic machineries of
cells with greatly different dimensions: the bacterium Escherichia coli and eggs
of the vertebrate Xenopus laevis. Combined with total internal reflection fluorescence
microscopy, these experimental setups allow for precise quantitative analyses
of membrane-bound proteins. The protocols described to obtain glass-supported
membranes from bacterial and vertebrate lipids can be used as starting points
for other reconstitution experiments. We believe that similar biochemical assays
will be instrumental to study the biochemistry and biophysics underlying a variety
of complex cellular tasks, such as signaling, vesicle trafficking, and cell motility.'
author:
- first_name: Phuong
full_name: Nguyen, Phuong
last_name: Nguyen
- first_name: Christine
full_name: Field, Christine
last_name: Field
- first_name: Aaron
full_name: Groen, Aaron
last_name: Groen
- first_name: Timothy
full_name: Mitchison, Timothy
last_name: Mitchison
- first_name: Martin
full_name: Loose, Martin
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
citation:
ama: 'Nguyen P, Field C, Groen A, Mitchison T, Loose M. Using supported bilayers
to study the spatiotemporal organization of membrane-bound proteins. In: Building
a Cell from Its Components Parts. Vol 128. Academic Press; 2015:223-241. doi:10.1016/bs.mcb.2015.01.007'
apa: Nguyen, P., Field, C., Groen, A., Mitchison, T., & Loose, M. (2015). Using
supported bilayers to study the spatiotemporal organization of membrane-bound
proteins. In Building a Cell from its Components Parts (Vol. 128, pp. 223–241).
Academic Press. https://doi.org/10.1016/bs.mcb.2015.01.007
chicago: Nguyen, Phuong, Christine Field, Aaron Groen, Timothy Mitchison, and Martin
Loose. “Using Supported Bilayers to Study the Spatiotemporal Organization of Membrane-Bound
Proteins.” In Building a Cell from Its Components Parts, 128:223–41. Academic
Press, 2015. https://doi.org/10.1016/bs.mcb.2015.01.007.
ieee: P. Nguyen, C. Field, A. Groen, T. Mitchison, and M. Loose, “Using supported
bilayers to study the spatiotemporal organization of membrane-bound proteins,”
in Building a Cell from its Components Parts, vol. 128, Academic Press,
2015, pp. 223–241.
ista: 'Nguyen P, Field C, Groen A, Mitchison T, Loose M. 2015.Using supported bilayers
to study the spatiotemporal organization of membrane-bound proteins. In: Building
a Cell from its Components Parts. vol. 128, 223–241.'
mla: Nguyen, Phuong, et al. “Using Supported Bilayers to Study the Spatiotemporal
Organization of Membrane-Bound Proteins.” Building a Cell from Its Components
Parts, vol. 128, Academic Press, 2015, pp. 223–41, doi:10.1016/bs.mcb.2015.01.007.
short: P. Nguyen, C. Field, A. Groen, T. Mitchison, M. Loose, in:, Building a Cell
from Its Components Parts, Academic Press, 2015, pp. 223–241.
date_created: 2018-12-11T11:52:38Z
date_published: 2015-04-08T00:00:00Z
date_updated: 2021-01-12T06:51:30Z
day: '08'
department:
- _id: MaLo
doi: 10.1016/bs.mcb.2015.01.007
external_id:
pmid:
- '25997350'
intvolume: ' 128'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578691/
month: '04'
oa: 1
oa_version: Submitted Version
page: 223 - 241
pmid: 1
publication: Building a Cell from its Components Parts
publication_status: published
publisher: Academic Press
publist_id: '5627'
quality_controlled: '1'
scopus_import: 1
status: public
title: Using supported bilayers to study the spatiotemporal organization of membrane-bound
proteins
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2015'
...
---
_id: '1551'
abstract:
- lang: eng
text: 'Reciprocal coevolution between host and pathogen is widely seen as a major
driver of evolution and biological innovation. Yet, to date, the underlying genetic
mechanisms and associated trait functions that are unique to rapid coevolutionary
change are generally unknown. We here combined experimental evolution of the bacterial
biocontrol agent Bacillus thuringiensis and its nematode host Caenorhabditis elegans
with large-scale phenotyping, whole genome analysis, and functional genetics to
demonstrate the selective benefit of pathogen virulence and the underlying toxin
genes during the adaptation process. We show that: (i) high virulence was specifically
favoured during pathogen–host coevolution rather than pathogen one-sided adaptation
to a nonchanging host or to an environment without host; (ii) the pathogen genotype
BT-679 with known nematocidal toxin genes and high virulence specifically swept
to fixation in all of the independent replicate populations under coevolution
but only some under one-sided adaptation; (iii) high virulence in the BT-679-dominated
populations correlated with elevated copy numbers of the plasmid containing the
nematocidal toxin genes; (iv) loss of virulence in a toxin-plasmid lacking BT-679
isolate was reconstituted by genetic reintroduction or external addition of the
toxins.We conclude that sustained coevolution is distinct from unidirectional
selection in shaping the pathogen''s genome and life history characteristics.
To our knowledge, this study is the first to characterize the pathogen genes involved
in coevolutionary adaptation in an animal host–pathogen interaction system.'
acknowledgement: We are very grateful for funding from the German Science Foundation
(DFG) to HS (SCHU 1415/8, SCHU 1415/9), PR (RO 2994/3), EBB (BO 2544/7), HL (LI
1690/2), AT (TE 976/2), RDS (SCHU 2522/1), JK (KU 1929/4); from the Kiel Excellence
Cluster Inflammation at Interfaces to HS and PR; and from the ISTFELLOW program
(Co-fund Marie Curie Actions of the European Commission) to LM.
author:
- first_name: Leila
full_name: El Masri, Leila
id: 349A6E66-F248-11E8-B48F-1D18A9856A87
last_name: El Masri
- first_name: Antoine
full_name: Branca, Antoine
last_name: Branca
- first_name: Anna
full_name: Sheppard, Anna
last_name: Sheppard
- first_name: Andrei
full_name: Papkou, Andrei
last_name: Papkou
- first_name: David
full_name: Laehnemann, David
last_name: Laehnemann
- first_name: Patrick
full_name: Guenther, Patrick
last_name: Guenther
- first_name: Swantje
full_name: Prahl, Swantje
last_name: Prahl
- first_name: Manja
full_name: Saebelfeld, Manja
last_name: Saebelfeld
- first_name: Jacqueline
full_name: Hollensteiner, Jacqueline
last_name: Hollensteiner
- first_name: Heiko
full_name: Liesegang, Heiko
last_name: Liesegang
- first_name: Elzbieta
full_name: Brzuszkiewicz, Elzbieta
last_name: Brzuszkiewicz
- first_name: Rolf
full_name: Daniel, Rolf
last_name: Daniel
- first_name: Nico
full_name: Michiels, Nico
last_name: Michiels
- first_name: Rebecca
full_name: Schulte, Rebecca
last_name: Schulte
- first_name: Joachim
full_name: Kurtz, Joachim
last_name: Kurtz
- first_name: Philip
full_name: Rosenstiel, Philip
last_name: Rosenstiel
- first_name: Arndt
full_name: Telschow, Arndt
last_name: Telschow
- first_name: Erich
full_name: Bornberg Bauer, Erich
last_name: Bornberg Bauer
- first_name: Hinrich
full_name: Schulenburg, Hinrich
last_name: Schulenburg
citation:
ama: 'El Masri L, Branca A, Sheppard A, et al. Host–pathogen coevolution: The selective
advantage of Bacillus thuringiensis virulence and its cry toxin genes. PLoS
Biology. 2015;13(6):1-30. doi:10.1371/journal.pbio.1002169'
apa: 'El Masri, L., Branca, A., Sheppard, A., Papkou, A., Laehnemann, D., Guenther,
P., … Schulenburg, H. (2015). Host–pathogen coevolution: The selective advantage
of Bacillus thuringiensis virulence and its cry toxin genes. PLoS Biology.
Public Library of Science. https://doi.org/10.1371/journal.pbio.1002169'
chicago: 'El Masri, Leila, Antoine Branca, Anna Sheppard, Andrei Papkou, David Laehnemann,
Patrick Guenther, Swantje Prahl, et al. “Host–Pathogen Coevolution: The Selective
Advantage of Bacillus Thuringiensis Virulence and Its Cry Toxin Genes.” PLoS
Biology. Public Library of Science, 2015. https://doi.org/10.1371/journal.pbio.1002169.'
ieee: 'L. El Masri et al., “Host–pathogen coevolution: The selective advantage
of Bacillus thuringiensis virulence and its cry toxin genes,” PLoS Biology,
vol. 13, no. 6. Public Library of Science, pp. 1–30, 2015.'
ista: 'El Masri L, Branca A, Sheppard A, Papkou A, Laehnemann D, Guenther P, Prahl
S, Saebelfeld M, Hollensteiner J, Liesegang H, Brzuszkiewicz E, Daniel R, Michiels
N, Schulte R, Kurtz J, Rosenstiel P, Telschow A, Bornberg Bauer E, Schulenburg
H. 2015. Host–pathogen coevolution: The selective advantage of Bacillus thuringiensis
virulence and its cry toxin genes. PLoS Biology. 13(6), 1–30.'
mla: 'El Masri, Leila, et al. “Host–Pathogen Coevolution: The Selective Advantage
of Bacillus Thuringiensis Virulence and Its Cry Toxin Genes.” PLoS Biology,
vol. 13, no. 6, Public Library of Science, 2015, pp. 1–30, doi:10.1371/journal.pbio.1002169.'
short: L. El Masri, A. Branca, A. Sheppard, A. Papkou, D. Laehnemann, P. Guenther,
S. Prahl, M. Saebelfeld, J. Hollensteiner, H. Liesegang, E. Brzuszkiewicz, R.
Daniel, N. Michiels, R. Schulte, J. Kurtz, P. Rosenstiel, A. Telschow, E. Bornberg
Bauer, H. Schulenburg, PLoS Biology 13 (2015) 1–30.
date_created: 2018-12-11T11:52:40Z
date_published: 2015-06-04T00:00:00Z
date_updated: 2021-01-12T06:51:33Z
day: '04'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1371/journal.pbio.1002169
ec_funded: 1
file:
- access_level: open_access
checksum: 30dee7a2c11ed09f2f5634655c0146f8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:13Z
date_updated: 2020-07-14T12:45:02Z
file_id: '5063'
file_name: IST-2016-481-v1+1_journal.pbio.1002169.pdf
file_size: 3468956
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 13'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1 - 30
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5620'
pubrep_id: '481'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Host–pathogen coevolution: The selective advantage of Bacillus thuringiensis
virulence and its cry toxin genes'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2015'
...
---
_id: '1549'
abstract:
- lang: eng
text: Nature has incorporated small photochromic molecules, colloquially termed
'photoswitches', in photoreceptor proteins to sense optical cues in photo-taxis
and vision. While Nature's ability to employ light-responsive functionalities
has long been recognized, it was not until recently that scientists designed,
synthesized and applied synthetic photochromes to manipulate many of which open
rapidly and locally in their native cell types, biological processes with the
temporal and spatial resolution of light. Ion channels in particular have come
to the forefront of proteins that can be put under the designer control of synthetic
photochromes. Photochromic ion channel controllers are comprised of three classes,
photochromic soluble ligands (PCLs), photochromic tethered ligands (PTLs) and
photochromic crosslinkers (PXs), and in each class ion channel functionality is
controlled through reversible changes in photochrome structure. By acting as light-dependent
ion channel agonists, antagonist or modulators, photochromic controllers effectively
converted a wide range of ion channels, including voltage-gated ion channels,
'leak channels', tri-, tetra- and pentameric ligand-gated ion channels, and temperaturesensitive
ion channels, into man-made photoreceptors. Control by photochromes can be reversible,
unlike in the case of 'caged' compounds, and non-invasive with high spatial precision,
unlike pharmacology and electrical manipulation. Here, we introduce design principles
of emerging photochromic molecules that act on ion channels and discuss the impact
that these molecules are beginning to have on ion channel biophysics and neuronal
physiology.
author:
- first_name: Catherine
full_name: Mckenzie, Catherine
id: 3EEDE19A-F248-11E8-B48F-1D18A9856A87
last_name: Mckenzie
- first_name: Inmaculada
full_name: Sanchez Romero, Inmaculada
id: 3D9C5D30-F248-11E8-B48F-1D18A9856A87
last_name: Sanchez Romero
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: 'Mckenzie C, Sanchez-Romero I, Janovjak HL. Flipping the photoswitch: Ion channels
under light control. In: Novel Chemical Tools to Study Ion Channel Biology.
Vol 869. Advances in Experimental Medicine and Biology. Springer; 2015:101-117.
doi:10.1007/978-1-4939-2845-3_6'
apa: 'Mckenzie, C., Sanchez-Romero, I., & Janovjak, H. L. (2015). Flipping the
photoswitch: Ion channels under light control. In Novel chemical tools to study
ion channel biology (Vol. 869, pp. 101–117). Springer. https://doi.org/10.1007/978-1-4939-2845-3_6'
chicago: 'Mckenzie, Catherine, Inmaculada Sanchez-Romero, and Harald L Janovjak.
“Flipping the Photoswitch: Ion Channels under Light Control.” In Novel Chemical
Tools to Study Ion Channel Biology, 869:101–17. Advances in Experimental Medicine
and Biology. Springer, 2015. https://doi.org/10.1007/978-1-4939-2845-3_6.'
ieee: 'C. Mckenzie, I. Sanchez-Romero, and H. L. Janovjak, “Flipping the photoswitch:
Ion channels under light control,” in Novel chemical tools to study ion channel
biology, vol. 869, Springer, 2015, pp. 101–117.'
ista: 'Mckenzie C, Sanchez-Romero I, Janovjak HL. 2015.Flipping the photoswitch:
Ion channels under light control. In: Novel chemical tools to study ion channel
biology. vol. 869, 101–117.'
mla: 'Mckenzie, Catherine, et al. “Flipping the Photoswitch: Ion Channels under
Light Control.” Novel Chemical Tools to Study Ion Channel Biology, vol.
869, Springer, 2015, pp. 101–17, doi:10.1007/978-1-4939-2845-3_6.'
short: C. Mckenzie, I. Sanchez-Romero, H.L. Janovjak, in:, Novel Chemical Tools
to Study Ion Channel Biology, Springer, 2015, pp. 101–117.
date_created: 2018-12-11T11:52:39Z
date_published: 2015-09-18T00:00:00Z
date_updated: 2021-01-12T06:51:32Z
day: '18'
ddc:
- '571'
- '576'
department:
- _id: HaJa
doi: 10.1007/978-1-4939-2845-3_6
file:
- access_level: open_access
checksum: bd1bfdf2423a0c3b6e7cabfa8b44bc0f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:02Z
date_updated: 2020-07-14T12:45:01Z
file_id: '4854'
file_name: IST-2017-839-v1+1_mckenzie.pdf
file_size: 1919655
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 869'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 101 - 117
publication: Novel chemical tools to study ion channel biology
publication_identifier:
isbn:
- 978-1-4939-2844-6
publication_status: published
publisher: Springer
publist_id: '5622'
pubrep_id: '839'
quality_controlled: '1'
scopus_import: 1
series_title: Advances in Experimental Medicine and Biology
status: public
title: 'Flipping the photoswitch: Ion channels under light control'
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 869
year: '2015'
...
---
_id: '1548'
abstract:
- lang: eng
text: Reproduction within a host and transmission to the next host are crucial for
the virulence and fitness of pathogens. Nevertheless, basic knowledge about such
parameters is often missing from the literature, even for well-studied bacteria,
such as Bacillus thuringiensis, an endospore-forming insect pathogen, which infects
its hosts via the oral route. To characterize bacterial replication success, we
made use of an experimental oral infection system for the red flour beetle Tribolium
castaneum and developed a flow cytometric assay for the quantification of both
spore ingestion by the individual beetle larvae and the resulting spore load after
bacterial replication and resporulation within cadavers. On average, spore numbers
increased 460-fold, showing that Bacillus thuringiensis grows and replicates successfully
in insect cadavers. By inoculating cadaver-derived spores and spores from bacterial
stock cultures into nutrient medium, we next investigated outgrowth characteristics
of vegetative cells and found that cadaver- derived bacteria showed reduced growth
compared to bacteria from the stock cultures. Interestingly, this reduced growth
was a consequence of inhibited spore germination, probably originating from the
host and resulting in reduced host mortality in subsequent infections by cadaver-derived
spores. Nevertheless, we further showed that Bacillus thuringiensis transmission
was possible via larval cannibalism when no other food was offered. These results
contribute to our understanding of the ecology of Bacillus thuringiensis as an
insect pathogen.
author:
- first_name: Barbara
full_name: Milutinovic, Barbara
id: 2CDC32B8-F248-11E8-B48F-1D18A9856A87
last_name: Milutinovic
orcid: 0000-0002-8214-4758
- first_name: Christina
full_name: Höfling, Christina
last_name: Höfling
- first_name: Momir
full_name: Futo, Momir
last_name: Futo
- first_name: Jörn
full_name: Scharsack, Jörn
last_name: Scharsack
- first_name: Joachim
full_name: Kurtz, Joachim
last_name: Kurtz
citation:
ama: 'Milutinovic B, Höfling C, Futo M, Scharsack J, Kurtz J. Infection of Tribolium
castaneum with Bacillus thuringiensis: Quantification of bacterial replication
within cadavers, transmission via cannibalism, and inhibition of spore germination.
Applied and Environmental Microbiology. 2015;81(23):8135-8144. doi:10.1128/AEM.02051-15'
apa: 'Milutinovic, B., Höfling, C., Futo, M., Scharsack, J., & Kurtz, J. (2015).
Infection of Tribolium castaneum with Bacillus thuringiensis: Quantification of
bacterial replication within cadavers, transmission via cannibalism, and inhibition
of spore germination. Applied and Environmental Microbiology. American
Society for Microbiology. https://doi.org/10.1128/AEM.02051-15'
chicago: 'Milutinovic, Barbara, Christina Höfling, Momir Futo, Jörn Scharsack, and
Joachim Kurtz. “Infection of Tribolium Castaneum with Bacillus Thuringiensis:
Quantification of Bacterial Replication within Cadavers, Transmission via Cannibalism,
and Inhibition of Spore Germination.” Applied and Environmental Microbiology.
American Society for Microbiology, 2015. https://doi.org/10.1128/AEM.02051-15.'
ieee: 'B. Milutinovic, C. Höfling, M. Futo, J. Scharsack, and J. Kurtz, “Infection
of Tribolium castaneum with Bacillus thuringiensis: Quantification of bacterial
replication within cadavers, transmission via cannibalism, and inhibition of spore
germination,” Applied and Environmental Microbiology, vol. 81, no. 23.
American Society for Microbiology, pp. 8135–8144, 2015.'
ista: 'Milutinovic B, Höfling C, Futo M, Scharsack J, Kurtz J. 2015. Infection of
Tribolium castaneum with Bacillus thuringiensis: Quantification of bacterial replication
within cadavers, transmission via cannibalism, and inhibition of spore germination.
Applied and Environmental Microbiology. 81(23), 8135–8144.'
mla: 'Milutinovic, Barbara, et al. “Infection of Tribolium Castaneum with Bacillus
Thuringiensis: Quantification of Bacterial Replication within Cadavers, Transmission
via Cannibalism, and Inhibition of Spore Germination.” Applied and Environmental
Microbiology, vol. 81, no. 23, American Society for Microbiology, 2015, pp.
8135–44, doi:10.1128/AEM.02051-15.'
short: B. Milutinovic, C. Höfling, M. Futo, J. Scharsack, J. Kurtz, Applied and
Environmental Microbiology 81 (2015) 8135–8144.
date_created: 2018-12-11T11:52:39Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T06:51:31Z
day: '01'
department:
- _id: SyCr
doi: 10.1128/AEM.02051-15
external_id:
pmid:
- '26386058'
intvolume: ' 81'
issue: '23'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651099/
month: '12'
oa: 1
oa_version: Submitted Version
page: 8135 - 8144
pmid: 1
publication: Applied and Environmental Microbiology
publication_status: published
publisher: American Society for Microbiology
publist_id: '5623'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Infection of Tribolium castaneum with Bacillus thuringiensis: Quantification
of bacterial replication within cadavers, transmission via cannibalism, and inhibition
of spore germination'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 81
year: '2015'
...
---
_id: '1550'
abstract:
- lang: eng
text: The medial ganglionic eminence (MGE) gives rise to the majority of mouse forebrain
interneurons. Here, we examine the lineage relationship among MGE-derived interneurons
using a replication-defective retroviral library containing a highly diverse set
of DNA barcodes. Recovering the barcodes from the mature progeny of infected progenitor
cells enabled us to unambiguously determine their respective lineal relationship.
We found that clonal dispersion occurs across large areas of the brain and is
not restricted by anatomical divisions. As such, sibling interneurons can populate
the cortex, hippocampus striatum, and globus pallidus. The majority of interneurons
appeared to be generated from asymmetric divisions of MGE progenitor cells, followed
by symmetric divisions within the subventricular zone. Altogether, our findings
uncover that lineage relationships do not appear to determine interneuron allocation
to particular regions. As such, it is likely that clonally related interneurons
have considerable flexibility as to the particular forebrain circuits to which
they can contribute.
acknowledgement: "Research in the G.F. laboratory is supported by NIH (NS 081297,
MH095147, and P01NS074972) and the Simons Foundation. Research in the S.H. laboratory
is supported by the European Union (FP7-CIG618444). C.M. is supported by EMBO ALTF
(1295-2012). X.H.J. is supported by EMBO (ALTF 303-2010) and HFSP (LT000078/2011-L).\r\n\r\n"
author:
- first_name: Christian
full_name: Mayer, Christian
last_name: Mayer
- first_name: Xavier
full_name: Jaglin, Xavier
last_name: Jaglin
- first_name: Lucy
full_name: Cobbs, Lucy
last_name: Cobbs
- first_name: Rachel
full_name: Bandler, Rachel
last_name: Bandler
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Constance
full_name: Cepko, Constance
last_name: Cepko
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Gord
full_name: Fishell, Gord
last_name: Fishell
citation:
ama: Mayer C, Jaglin X, Cobbs L, et al. Clonally related forebrain interneurons
disperse broadly across both functional areas and structural boundaries. Neuron.
2015;87(5):989-998. doi:10.1016/j.neuron.2015.07.011
apa: Mayer, C., Jaglin, X., Cobbs, L., Bandler, R., Streicher, C., Cepko, C., …
Fishell, G. (2015). Clonally related forebrain interneurons disperse broadly across
both functional areas and structural boundaries. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2015.07.011
chicago: Mayer, Christian, Xavier Jaglin, Lucy Cobbs, Rachel Bandler, Carmen Streicher,
Constance Cepko, Simon Hippenmeyer, and Gord Fishell. “Clonally Related Forebrain
Interneurons Disperse Broadly across Both Functional Areas and Structural Boundaries.”
Neuron. Elsevier, 2015. https://doi.org/10.1016/j.neuron.2015.07.011.
ieee: C. Mayer et al., “Clonally related forebrain interneurons disperse
broadly across both functional areas and structural boundaries,” Neuron,
vol. 87, no. 5. Elsevier, pp. 989–998, 2015.
ista: Mayer C, Jaglin X, Cobbs L, Bandler R, Streicher C, Cepko C, Hippenmeyer S,
Fishell G. 2015. Clonally related forebrain interneurons disperse broadly across
both functional areas and structural boundaries. Neuron. 87(5), 989–998.
mla: Mayer, Christian, et al. “Clonally Related Forebrain Interneurons Disperse
Broadly across Both Functional Areas and Structural Boundaries.” Neuron,
vol. 87, no. 5, Elsevier, 2015, pp. 989–98, doi:10.1016/j.neuron.2015.07.011.
short: C. Mayer, X. Jaglin, L. Cobbs, R. Bandler, C. Streicher, C. Cepko, S. Hippenmeyer,
G. Fishell, Neuron 87 (2015) 989–998.
date_created: 2018-12-11T11:52:40Z
date_published: 2015-09-02T00:00:00Z
date_updated: 2021-01-12T06:51:32Z
day: '02'
department:
- _id: SiHi
doi: 10.1016/j.neuron.2015.07.011
external_id:
pmid:
- '26299473'
intvolume: ' 87'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560602/
month: '09'
oa: 1
oa_version: Submitted Version
page: 989 - 998
pmid: 1
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5621'
quality_controlled: '1'
scopus_import: 1
status: public
title: Clonally related forebrain interneurons disperse broadly across both functional
areas and structural boundaries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 87
year: '2015'
...
---
_id: '1547'
abstract:
- lang: eng
text: Let G be a graph on the vertex set V(G) = {x1,…,xn} with the edge set E(G),
and let R = K[x1,…, xn] be the polynomial ring over a field K. Two monomial ideals
are associated to G, the edge ideal I(G) generated by all monomials xixj with
{xi,xj} ∈ E(G), and the vertex cover ideal IG generated by monomials ∏xi∈Cxi for
all minimal vertex covers C of G. A minimal vertex cover of G is a subset C ⊂
V(G) such that each edge has at least one vertex in C and no proper subset of
C has the same property. Indeed, the vertex cover ideal of G is the Alexander
dual of the edge ideal of G. In this paper, for an unmixed bipartite graph G we
consider the lattice of vertex covers LG and we explicitly describe the minimal
free resolution of the ideal associated to LG which is exactly the vertex cover
ideal of G. Then we compute depth, projective dimension, regularity and extremal
Betti numbers of R/I(G) in terms of the associated lattice.
author:
- first_name: Fatemeh
full_name: Mohammadi, Fatemeh
id: 2C29581E-F248-11E8-B48F-1D18A9856A87
last_name: Mohammadi
- first_name: Somayeh
full_name: Moradi, Somayeh
last_name: Moradi
citation:
ama: Mohammadi F, Moradi S. Resolution of unmixed bipartite graphs. Bulletin
of the Korean Mathematical Society. 2015;52(3):977-986. doi:10.4134/BKMS.2015.52.3.977
apa: Mohammadi, F., & Moradi, S. (2015). Resolution of unmixed bipartite graphs.
Bulletin of the Korean Mathematical Society. Korean Mathematical Society.
https://doi.org/10.4134/BKMS.2015.52.3.977
chicago: Mohammadi, Fatemeh, and Somayeh Moradi. “Resolution of Unmixed Bipartite
Graphs.” Bulletin of the Korean Mathematical Society. Korean Mathematical
Society, 2015. https://doi.org/10.4134/BKMS.2015.52.3.977.
ieee: F. Mohammadi and S. Moradi, “Resolution of unmixed bipartite graphs,” Bulletin
of the Korean Mathematical Society, vol. 52, no. 3. Korean Mathematical Society,
pp. 977–986, 2015.
ista: Mohammadi F, Moradi S. 2015. Resolution of unmixed bipartite graphs. Bulletin
of the Korean Mathematical Society. 52(3), 977–986.
mla: Mohammadi, Fatemeh, and Somayeh Moradi. “Resolution of Unmixed Bipartite Graphs.”
Bulletin of the Korean Mathematical Society, vol. 52, no. 3, Korean Mathematical
Society, 2015, pp. 977–86, doi:10.4134/BKMS.2015.52.3.977.
short: F. Mohammadi, S. Moradi, Bulletin of the Korean Mathematical Society 52 (2015)
977–986.
date_created: 2018-12-11T11:52:39Z
date_published: 2015-05-31T00:00:00Z
date_updated: 2021-01-12T06:51:31Z
day: '31'
department:
- _id: CaUh
doi: 10.4134/BKMS.2015.52.3.977
intvolume: ' 52'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0901.3015
month: '05'
oa: 1
oa_version: Preprint
page: 977 - 986
publication: Bulletin of the Korean Mathematical Society
publication_identifier:
eissn:
- 2234-3016
publication_status: published
publisher: Korean Mathematical Society
publist_id: '5624'
quality_controlled: '1'
scopus_import: 1
status: public
title: Resolution of unmixed bipartite graphs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 52
year: '2015'
...
---
_id: '1556'
abstract:
- lang: eng
text: The elongator complex subunit 2 (ELP2) protein, one subunit of an evolutionarily
conserved histone acetyltransferase complex, has been shown to participate in
leaf patterning, plant immune and abiotic stress responses in Arabidopsis thaliana.
Here, its role in root development was explored. Compared to the wild type, the
elp2 mutant exhibited an accelerated differentiation of its root stem cells and
cell division was more active in its quiescent centre (QC). The key transcription
factors responsible for maintaining root stem cell and QC identity, such as AP2
transcription factors PLT1 (PLETHORA1) and PLT2 (PLETHORA2), GRAS transcription
factors such as SCR (SCARECROW) and SHR (SHORT ROOT) and WUSCHEL-RELATED HOMEOBOX5
transcription factor WOX5, were all strongly down-regulated in the mutant. On
the other hand, expression of the G2/M transition activator CYCB1 was substantially
induced in elp2. The auxin efflux transporters PIN1 and PIN2 showed decreased
protein levels and PIN1 also displayed mild polarity alterations in elp2, which
resulted in a reduced auxin content in the root tip. Either the acetylation or
methylation level of each of these genes differed between the mutant and the wild
type, suggesting that the ELP2 regulation of root development involves the epigenetic
modification of a range of transcription factors and other developmental regulators.
author:
- first_name: Yuebin
full_name: Jia, Yuebin
last_name: Jia
- first_name: Huiyu
full_name: Tian, Huiyu
last_name: Tian
- first_name: Hongjiang
full_name: Li, Hongjiang
id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0001-5039-9660
- first_name: Qianqian
full_name: Yu, Qianqian
last_name: Yu
- first_name: Lei
full_name: Wang, Lei
last_name: Wang
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Zhaojun
full_name: Ding, Zhaojun
last_name: Ding
citation:
ama: Jia Y, Tian H, Li H, et al. The Arabidopsis thaliana elongator complex subunit
2 epigenetically affects root development. Journal of Experimental Botany.
2015;66(15):4631-4642. doi:10.1093/jxb/erv230
apa: Jia, Y., Tian, H., Li, H., Yu, Q., Wang, L., Friml, J., & Ding, Z. (2015).
The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root
development. Journal of Experimental Botany. Oxford University Press. https://doi.org/10.1093/jxb/erv230
chicago: Jia, Yuebin, Huiyu Tian, Hongjiang Li, Qianqian Yu, Lei Wang, Jiří Friml,
and Zhaojun Ding. “The Arabidopsis Thaliana Elongator Complex Subunit 2 Epigenetically
Affects Root Development.” Journal of Experimental Botany. Oxford University
Press, 2015. https://doi.org/10.1093/jxb/erv230.
ieee: Y. Jia et al., “The Arabidopsis thaliana elongator complex subunit
2 epigenetically affects root development,” Journal of Experimental Botany,
vol. 66, no. 15. Oxford University Press, pp. 4631–4642, 2015.
ista: Jia Y, Tian H, Li H, Yu Q, Wang L, Friml J, Ding Z. 2015. The Arabidopsis
thaliana elongator complex subunit 2 epigenetically affects root development.
Journal of Experimental Botany. 66(15), 4631–4642.
mla: Jia, Yuebin, et al. “The Arabidopsis Thaliana Elongator Complex Subunit 2 Epigenetically
Affects Root Development.” Journal of Experimental Botany, vol. 66, no.
15, Oxford University Press, 2015, pp. 4631–42, doi:10.1093/jxb/erv230.
short: Y. Jia, H. Tian, H. Li, Q. Yu, L. Wang, J. Friml, Z. Ding, Journal of Experimental
Botany 66 (2015) 4631–4642.
date_created: 2018-12-11T11:52:42Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:35Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1093/jxb/erv230
file:
- access_level: open_access
checksum: 257919be0ce3d306185d3891ad7acf39
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:02Z
date_updated: 2020-07-14T12:45:02Z
file_id: '5051'
file_name: IST-2016-480-v1+1_J._Exp._Bot.-2015-Jia-4631-42.pdf
file_size: 7753043
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 66'
issue: '15'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 4631 - 4642
publication: Journal of Experimental Botany
publication_status: published
publisher: Oxford University Press
publist_id: '5615'
pubrep_id: '480'
quality_controlled: '1'
scopus_import: 1
status: public
title: The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects
root development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 66
year: '2015'
...
---
_id: '1555'
abstract:
- lang: eng
text: We show that incorporating spatial dispersal of individuals into a simple
vaccination epidemic model may give rise to a model that exhibits rich dynamical
behavior. Using an SIVS (susceptible-infected-vaccinated-susceptible) model as
a basis, we describe the spread of an infectious disease in a population split
into two regions. In each subpopulation, both forward and backward bifurcations
can occur. This implies that for disconnected regions the two-patch system may
admit several steady states. We consider traveling between the regions and investigate
the impact of spatial dispersal of individuals on the model dynamics. We establish
conditions for the existence of multiple nontrivial steady states in the system,
and we study the structure of the equilibria. The mathematical analysis reveals
an unusually rich dynamical behavior, not normally found in the simple epidemic
models. In addition to the disease-free equilibrium, eight endemic equilibria
emerge from backward transcritical and saddle-node bifurcation points, forming
an interesting bifurcation diagram. Stability of steady states, their bifurcations,
and the global dynamics are investigated with analytical tools, numerical simulations,
and rigorous set-oriented numerical computations.
acknowledgement: Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg,
Austria (pawel.pilarczyk@ist.ac.at). This author’s work was partially supported
by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework
Programme (FP7/2007-2013) under REA grant agreement 622033, by Fundo Europeu de
Desenvolvimento Regional (FEDER) through COMPETE—Programa Operacional Factores de
Competitividade (POFC), by the Portuguese national funds through Funda ̧caoparaaCiˆencia
e a Tecnologia (FCT) in the framework of the research project FCOMP-01-0124-FEDER-010645
(ref. FCT PTDC/MAT/098871/2008), and by European Research Council through StG 259559
in the framework of the EPIDELAY project.
article_processing_charge: No
article_type: original
author:
- first_name: Diána
full_name: Knipl, Diána
last_name: Knipl
- first_name: Pawel
full_name: Pilarczyk, Pawel
id: 3768D56A-F248-11E8-B48F-1D18A9856A87
last_name: Pilarczyk
- first_name: Gergely
full_name: Röst, Gergely
last_name: Röst
citation:
ama: Knipl D, Pilarczyk P, Röst G. Rich bifurcation structure in a two patch vaccination
model. SIAM Journal on Applied Dynamical Systems. 2015;14(2):980-1017.
doi:10.1137/140993934
apa: Knipl, D., Pilarczyk, P., & Röst, G. (2015). Rich bifurcation structure
in a two patch vaccination model. SIAM Journal on Applied Dynamical Systems.
Society for Industrial and Applied Mathematics . https://doi.org/10.1137/140993934
chicago: Knipl, Diána, Pawel Pilarczyk, and Gergely Röst. “Rich Bifurcation Structure
in a Two Patch Vaccination Model.” SIAM Journal on Applied Dynamical Systems.
Society for Industrial and Applied Mathematics , 2015. https://doi.org/10.1137/140993934.
ieee: D. Knipl, P. Pilarczyk, and G. Röst, “Rich bifurcation structure in a two
patch vaccination model,” SIAM Journal on Applied Dynamical Systems, vol.
14, no. 2. Society for Industrial and Applied Mathematics , pp. 980–1017, 2015.
ista: Knipl D, Pilarczyk P, Röst G. 2015. Rich bifurcation structure in a two patch
vaccination model. SIAM Journal on Applied Dynamical Systems. 14(2), 980–1017.
mla: Knipl, Diána, et al. “Rich Bifurcation Structure in a Two Patch Vaccination
Model.” SIAM Journal on Applied Dynamical Systems, vol. 14, no. 2, Society
for Industrial and Applied Mathematics , 2015, pp. 980–1017, doi:10.1137/140993934.
short: D. Knipl, P. Pilarczyk, G. Röst, SIAM Journal on Applied Dynamical Systems
14 (2015) 980–1017.
date_created: 2018-12-11T11:52:42Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:51:34Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1137/140993934
ec_funded: 1
intvolume: ' 14'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://discovery.ucl.ac.uk/1473750/1/99393.pdf
month: '01'
oa: 1
oa_version: Published Version
page: 980 - 1017
project:
- _id: 255F06BE-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '622033'
name: Persistent Homology - Images, Data and Maps
publication: SIAM Journal on Applied Dynamical Systems
publication_identifier:
eissn:
- 1536-0040
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5616'
quality_controlled: '1'
scopus_import: 1
status: public
title: Rich bifurcation structure in a two patch vaccination model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2015'
...
---
_id: '1559'
abstract:
- lang: eng
text: 'There are deep, yet largely unexplored, connections between computer science
and biology. Both disciplines examine how information proliferates in time and
space. Central results in computer science describe the complexity of algorithms
that solve certain classes of problems. An algorithm is deemed efficient if it
can solve a problem in polynomial time, which means the running time of the algorithm
is a polynomial function of the length of the input. There are classes of harder
problems for which the fastest possible algorithm requires exponential time. Another
criterion is the space requirement of the algorithm. There is a crucial distinction
between algorithms that can find a solution, verify a solution, or list several
distinct solutions in given time and space. The complexity hierarchy that is generated
in this way is the foundation of theoretical computer science. Precise complexity
results can be notoriously difficult. The famous question whether polynomial time
equals nondeterministic polynomial time (i.e., P = NP) is one of the hardest open
problems in computer science and all of mathematics. Here, we consider simple
processes of ecological and evolutionary spatial dynamics. The basic question
is: What is the probability that a new invader (or a new mutant)will take over
a resident population?We derive precise complexity results for a variety of scenarios.
We therefore show that some fundamental questions in this area cannot be answered
by simple equations (assuming that P is not equal to NP).'
author:
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Ibsen-Jensen R, Chatterjee K, Nowak M. Computational complexity of ecological
and evolutionary spatial dynamics. PNAS. 2015;112(51):15636-15641. doi:10.1073/pnas.1511366112
apa: Ibsen-Jensen, R., Chatterjee, K., & Nowak, M. (2015). Computational complexity
of ecological and evolutionary spatial dynamics. PNAS. National Academy
of Sciences. https://doi.org/10.1073/pnas.1511366112
chicago: Ibsen-Jensen, Rasmus, Krishnendu Chatterjee, and Martin Nowak. “Computational
Complexity of Ecological and Evolutionary Spatial Dynamics.” PNAS. National
Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1511366112.
ieee: R. Ibsen-Jensen, K. Chatterjee, and M. Nowak, “Computational complexity of
ecological and evolutionary spatial dynamics,” PNAS, vol. 112, no. 51.
National Academy of Sciences, pp. 15636–15641, 2015.
ista: Ibsen-Jensen R, Chatterjee K, Nowak M. 2015. Computational complexity of ecological
and evolutionary spatial dynamics. PNAS. 112(51), 15636–15641.
mla: Ibsen-Jensen, Rasmus, et al. “Computational Complexity of Ecological and Evolutionary
Spatial Dynamics.” PNAS, vol. 112, no. 51, National Academy of Sciences,
2015, pp. 15636–41, doi:10.1073/pnas.1511366112.
short: R. Ibsen-Jensen, K. Chatterjee, M. Nowak, PNAS 112 (2015) 15636–15641.
date_created: 2018-12-11T11:52:43Z
date_published: 2015-12-22T00:00:00Z
date_updated: 2021-01-12T06:51:36Z
day: '22'
department:
- _id: KrCh
doi: 10.1073/pnas.1511366112
external_id:
pmid:
- '26644569'
intvolume: ' 112'
issue: '51'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697423/
month: '12'
oa: 1
oa_version: Submitted Version
page: 15636 - 15641
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5612'
quality_controlled: '1'
scopus_import: 1
status: public
title: Computational complexity of ecological and evolutionary spatial dynamics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1554'
abstract:
- lang: eng
text: The visualization of hormonal signaling input and output is key to understanding
how multicellular development is regulated. The plant signaling molecule auxin
triggers many growth and developmental responses, but current tools lack the sensitivity
or precision to visualize these. We developed a set of fluorescent reporters that
allow sensitive and semiquantitative readout of auxin responses at cellular resolution
in Arabidopsis thaliana. These generic tools are suitable for any transformable
plant species.
author:
- first_name: Cheyang
full_name: Liao, Cheyang
last_name: Liao
- first_name: Wouter
full_name: Smet, Wouter
last_name: Smet
- first_name: Géraldine
full_name: Brunoud, Géraldine
last_name: Brunoud
- first_name: Saiko
full_name: Yoshida, Saiko
id: 2E46069C-F248-11E8-B48F-1D18A9856A87
last_name: Yoshida
- first_name: Teva
full_name: Vernoux, Teva
last_name: Vernoux
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
citation:
ama: Liao C, Smet W, Brunoud G, Yoshida S, Vernoux T, Weijers D. Reporters for sensitive
and quantitative measurement of auxin response. Nature Methods. 2015;12(3):207-210.
doi:10.1038/nmeth.3279
apa: Liao, C., Smet, W., Brunoud, G., Yoshida, S., Vernoux, T., & Weijers, D.
(2015). Reporters for sensitive and quantitative measurement of auxin response.
Nature Methods. Nature Publishing Group. https://doi.org/10.1038/nmeth.3279
chicago: Liao, Cheyang, Wouter Smet, Géraldine Brunoud, Saiko Yoshida, Teva Vernoux,
and Dolf Weijers. “Reporters for Sensitive and Quantitative Measurement of Auxin
Response.” Nature Methods. Nature Publishing Group, 2015. https://doi.org/10.1038/nmeth.3279.
ieee: C. Liao, W. Smet, G. Brunoud, S. Yoshida, T. Vernoux, and D. Weijers, “Reporters
for sensitive and quantitative measurement of auxin response,” Nature Methods,
vol. 12, no. 3. Nature Publishing Group, pp. 207–210, 2015.
ista: Liao C, Smet W, Brunoud G, Yoshida S, Vernoux T, Weijers D. 2015. Reporters
for sensitive and quantitative measurement of auxin response. Nature Methods.
12(3), 207–210.
mla: Liao, Cheyang, et al. “Reporters for Sensitive and Quantitative Measurement
of Auxin Response.” Nature Methods, vol. 12, no. 3, Nature Publishing Group,
2015, pp. 207–10, doi:10.1038/nmeth.3279.
short: C. Liao, W. Smet, G. Brunoud, S. Yoshida, T. Vernoux, D. Weijers, Nature
Methods 12 (2015) 207–210.
date_created: 2018-12-11T11:52:41Z
date_published: 2015-02-26T00:00:00Z
date_updated: 2021-01-12T06:51:34Z
day: '26'
department:
- _id: JiFr
doi: 10.1038/nmeth.3279
external_id:
pmid:
- '25643149'
intvolume: ' 12'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344836/
month: '02'
oa: 1
oa_version: Submitted Version
page: 207 - 210
pmid: 1
publication: Nature Methods
publication_status: published
publisher: Nature Publishing Group
publist_id: '5617'
quality_controlled: '1'
scopus_import: 1
status: public
title: Reporters for sensitive and quantitative measurement of auxin response
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2015'
...
---
_id: '1565'
abstract:
- lang: eng
text: Leptin is an adipokine produced by the adipose tissue regulating body weight
through its appetite-suppressing effect. Besides being expressed in the hypothalamus
and hippocampus, leptin receptors (ObRs) are also present in chromaffin cells
of the adrenal medulla. In the present study, we report the effect of leptin on
mouse chromaffin cell (MCC) functionality, focusing on cell excitability and catecholamine
secretion. Acute application of leptin (1 nm) on spontaneously firing MCCs caused
a slowly developing membrane hyperpolarization followed by complete blockade of
action potential (AP) firing. This inhibitory effect at rest was abolished by
the BK channel blocker paxilline (1 μm), suggesting the involvement of BK potassium
channels. Single-channel recordings in 'perforated microvesicles' confirmed that
leptin increased BK channel open probability without altering its unitary conductance.
BK channel up-regulation was associated with the phosphoinositide 3-kinase (PI3K)
signalling cascade because the PI3K specific inhibitor wortmannin (100 nm) fully
prevented BK current increase. We also tested the effect of leptin on evoked AP
firing and Ca2+-driven exocytosis. Although leptin preserves well-adapted AP trains
of lower frequency, APs are broader and depolarization-evoked exocytosis is increased
as a result of the larger size of the ready-releasable pool and higher frequency
of vesicle release. The kinetics and quantal size of single secretory events remained
unaltered. Leptin had no effect on firing and secretion in db-/db- mice lacking
the ObR gene, confirming its specificity. In conclusion, leptin exhibits a dual
action on MCC activity. It dampens AP firing at rest but preserves AP firing and
increases catecholamine secretion during sustained stimulation, highlighting the
importance of the adipo-adrenal axis in the leptin-mediated increase of sympathetic
tone and catecholamine release.
acknowledgement: "This work was supported by the Compagnia di San Paolo Foundation
‘Neuroscience Program’ to VC and ‘Progetto di Ateneo 2011-13’ to EC.\r\nWe thank
Dr Claudio Franchino for cell preparation and for providing excellent technical
support."
author:
- first_name: Daniela
full_name: Gavello, Daniela
last_name: Gavello
- first_name: David H
full_name: Vandael, David H
id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
last_name: Vandael
orcid: 0000-0001-7577-1676
- first_name: Sara
full_name: Gosso, Sara
last_name: Gosso
- first_name: Emilio
full_name: Carbone, Emilio
last_name: Carbone
- first_name: Valentina
full_name: Carabelli, Valentina
last_name: Carabelli
citation:
ama: Gavello D, Vandael DH, Gosso S, Carbone E, Carabelli V. Dual action of leptin
on rest-firing and stimulated catecholamine release via phosphoinositide 3-kinase-riven
BK channel up-regulation in mouse chromaffin cells. Journal of Physiology.
2015;593(22):4835-4853. doi:10.1113/JP271078
apa: Gavello, D., Vandael, D. H., Gosso, S., Carbone, E., & Carabelli, V. (2015).
Dual action of leptin on rest-firing and stimulated catecholamine release via
phosphoinositide 3-kinase-riven BK channel up-regulation in mouse chromaffin cells.
Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1113/JP271078
chicago: Gavello, Daniela, David H Vandael, Sara Gosso, Emilio Carbone, and Valentina
Carabelli. “Dual Action of Leptin on Rest-Firing and Stimulated Catecholamine
Release via Phosphoinositide 3-Kinase-Riven BK Channel up-Regulation in Mouse
Chromaffin Cells.” Journal of Physiology. Wiley-Blackwell, 2015. https://doi.org/10.1113/JP271078.
ieee: D. Gavello, D. H. Vandael, S. Gosso, E. Carbone, and V. Carabelli, “Dual action
of leptin on rest-firing and stimulated catecholamine release via phosphoinositide
3-kinase-riven BK channel up-regulation in mouse chromaffin cells,” Journal
of Physiology, vol. 593, no. 22. Wiley-Blackwell, pp. 4835–4853, 2015.
ista: Gavello D, Vandael DH, Gosso S, Carbone E, Carabelli V. 2015. Dual action
of leptin on rest-firing and stimulated catecholamine release via phosphoinositide
3-kinase-riven BK channel up-regulation in mouse chromaffin cells. Journal of
Physiology. 593(22), 4835–4853.
mla: Gavello, Daniela, et al. “Dual Action of Leptin on Rest-Firing and Stimulated
Catecholamine Release via Phosphoinositide 3-Kinase-Riven BK Channel up-Regulation
in Mouse Chromaffin Cells.” Journal of Physiology, vol. 593, no. 22, Wiley-Blackwell,
2015, pp. 4835–53, doi:10.1113/JP271078.
short: D. Gavello, D.H. Vandael, S. Gosso, E. Carbone, V. Carabelli, Journal of
Physiology 593 (2015) 4835–4853.
date_created: 2018-12-11T11:52:45Z
date_published: 2015-11-15T00:00:00Z
date_updated: 2021-01-12T06:51:38Z
day: '15'
department:
- _id: PeJo
doi: 10.1113/JP271078
external_id:
pmid:
- '26282459'
intvolume: ' 593'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650409/
month: '11'
oa: 1
oa_version: Submitted Version
page: 4835 - 4853
pmid: 1
publication: Journal of Physiology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5606'
quality_controlled: '1'
scopus_import: 1
status: public
title: Dual action of leptin on rest-firing and stimulated catecholamine release via
phosphoinositide 3-kinase-riven BK channel up-regulation in mouse chromaffin cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 593
year: '2015'
...
---
_id: '1564'
article_number: '145'
author:
- first_name: Matthieu
full_name: Gilson, Matthieu
last_name: Gilson
- first_name: Cristina
full_name: Savin, Cristina
id: 3933349E-F248-11E8-B48F-1D18A9856A87
last_name: Savin
- first_name: Friedemann
full_name: Zenke, Friedemann
last_name: Zenke
citation:
ama: 'Gilson M, Savin C, Zenke F. Editorial: Emergent neural computation from the
interaction of different forms of plasticity. Frontiers in Computational Neuroscience.
2015;9(11). doi:10.3389/fncom.2015.00145'
apa: 'Gilson, M., Savin, C., & Zenke, F. (2015). Editorial: Emergent neural
computation from the interaction of different forms of plasticity. Frontiers
in Computational Neuroscience. Frontiers Research Foundation. https://doi.org/10.3389/fncom.2015.00145'
chicago: 'Gilson, Matthieu, Cristina Savin, and Friedemann Zenke. “Editorial: Emergent
Neural Computation from the Interaction of Different Forms of Plasticity.” Frontiers
in Computational Neuroscience. Frontiers Research Foundation, 2015. https://doi.org/10.3389/fncom.2015.00145.'
ieee: 'M. Gilson, C. Savin, and F. Zenke, “Editorial: Emergent neural computation
from the interaction of different forms of plasticity,” Frontiers in Computational
Neuroscience, vol. 9, no. 11. Frontiers Research Foundation, 2015.'
ista: 'Gilson M, Savin C, Zenke F. 2015. Editorial: Emergent neural computation
from the interaction of different forms of plasticity. Frontiers in Computational
Neuroscience. 9(11), 145.'
mla: 'Gilson, Matthieu, et al. “Editorial: Emergent Neural Computation from the
Interaction of Different Forms of Plasticity.” Frontiers in Computational Neuroscience,
vol. 9, no. 11, 145, Frontiers Research Foundation, 2015, doi:10.3389/fncom.2015.00145.'
short: M. Gilson, C. Savin, F. Zenke, Frontiers in Computational Neuroscience 9
(2015).
date_created: 2018-12-11T11:52:45Z
date_published: 2015-11-30T00:00:00Z
date_updated: 2021-01-12T06:51:37Z
day: '30'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.3389/fncom.2015.00145
ec_funded: 1
file:
- access_level: open_access
checksum: cea73b6d3ef1579f32da10b82f4de4fd
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:09Z
date_updated: 2020-07-14T12:45:02Z
file_id: '4927'
file_name: IST-2016-479-v1+1_fncom-09-00145.pdf
file_size: 187038
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Frontiers in Computational Neuroscience
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '5607'
pubrep_id: '479'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Editorial: Emergent neural computation from the interaction of different forms
of plasticity'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2015'
...
---
_id: '1574'
abstract:
- lang: eng
text: Multiple plant developmental processes, such as lateral root development,
depend on auxin distribution patterns that are in part generated by the PIN-formed
family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7
(ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly
form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription
in planta to steer the early steps of lateral root formation. This regulatory
mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli,
potentially maintaining and enhancing the robustness of the auxin flux directionality
during lateral root development. The cooperative action between canonical auxin
signalling and other transcription factors might constitute a general mechanism
by which transcriptional auxin-sensitivity can be regulated at a tissue-specific
level.
acknowledgement: 'of the European Research Council (project ERC-2011-StG-20101109-PSDP)
(to J.F.), a FEBS long-term fellowship (to P.M.) '
article_number: '8821'
author:
- first_name: Qian
full_name: Chen, Qian
last_name: Chen
- first_name: Yang
full_name: Liu, Yang
last_name: Liu
- first_name: Steven
full_name: Maere, Steven
last_name: Maere
- first_name: Eunkyoung
full_name: Lee, Eunkyoung
last_name: Lee
- first_name: Gert
full_name: Van Isterdael, Gert
last_name: Van Isterdael
- first_name: Zidian
full_name: Xie, Zidian
last_name: Xie
- first_name: Wei
full_name: Xuan, Wei
last_name: Xuan
- first_name: Jessica
full_name: Lucas, Jessica
last_name: Lucas
- first_name: Valya
full_name: Vassileva, Valya
last_name: Vassileva
- first_name: Saeko
full_name: Kitakura, Saeko
last_name: Kitakura
- first_name: Peter
full_name: Marhavy, Peter
id: 3F45B078-F248-11E8-B48F-1D18A9856A87
last_name: Marhavy
orcid: 0000-0001-5227-5741
- first_name: Krzysztof T
full_name: Wabnik, Krzysztof T
id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
last_name: Wabnik
orcid: 0000-0001-7263-0560
- first_name: Niko
full_name: Geldner, Niko
last_name: Geldner
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Jie
full_name: Le, Jie
last_name: Le
- first_name: Hidehiro
full_name: Fukaki, Hidehiro
last_name: Fukaki
- first_name: Erich
full_name: Grotewold, Erich
last_name: Grotewold
- first_name: Chuanyou
full_name: Li, Chuanyou
last_name: Li
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Fred
full_name: Sack, Fred
last_name: Sack
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
citation:
ama: Chen Q, Liu Y, Maere S, et al. A coherent transcriptional feed-forward motif
model for mediating auxin-sensitive PIN3 expression during lateral root development.
Nature Communications. 2015;6. doi:10.1038/ncomms9821
apa: Chen, Q., Liu, Y., Maere, S., Lee, E., Van Isterdael, G., Xie, Z., … Vanneste,
S. (2015). A coherent transcriptional feed-forward motif model for mediating auxin-sensitive
PIN3 expression during lateral root development. Nature Communications.
Nature Publishing Group. https://doi.org/10.1038/ncomms9821
chicago: Chen, Qian, Yang Liu, Steven Maere, Eunkyoung Lee, Gert Van Isterdael,
Zidian Xie, Wei Xuan, et al. “A Coherent Transcriptional Feed-Forward Motif Model
for Mediating Auxin-Sensitive PIN3 Expression during Lateral Root Development.”
Nature Communications. Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms9821.
ieee: Q. Chen et al., “A coherent transcriptional feed-forward motif model
for mediating auxin-sensitive PIN3 expression during lateral root development,”
Nature Communications, vol. 6. Nature Publishing Group, 2015.
ista: Chen Q, Liu Y, Maere S, Lee E, Van Isterdael G, Xie Z, Xuan W, Lucas J, Vassileva
V, Kitakura S, Marhavý P, Wabnik KT, Geldner N, Benková E, Le J, Fukaki H, Grotewold
E, Li C, Friml J, Sack F, Beeckman T, Vanneste S. 2015. A coherent transcriptional
feed-forward motif model for mediating auxin-sensitive PIN3 expression during
lateral root development. Nature Communications. 6, 8821.
mla: Chen, Qian, et al. “A Coherent Transcriptional Feed-Forward Motif Model for
Mediating Auxin-Sensitive PIN3 Expression during Lateral Root Development.” Nature
Communications, vol. 6, 8821, Nature Publishing Group, 2015, doi:10.1038/ncomms9821.
short: Q. Chen, Y. Liu, S. Maere, E. Lee, G. Van Isterdael, Z. Xie, W. Xuan, J.
Lucas, V. Vassileva, S. Kitakura, P. Marhavý, K.T. Wabnik, N. Geldner, E. Benková,
J. Le, H. Fukaki, E. Grotewold, C. Li, J. Friml, F. Sack, T. Beeckman, S. Vanneste,
Nature Communications 6 (2015).
date_created: 2018-12-11T11:52:48Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2021-01-12T06:51:42Z
day: '18'
ddc:
- '580'
department:
- _id: EvBe
- _id: JiFr
doi: 10.1038/ncomms9821
file:
- access_level: open_access
checksum: 8ff5c108899b548806e1cb7a302fe76d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:32Z
date_updated: 2020-07-14T12:45:02Z
file_id: '5085'
file_name: IST-2016-477-v1+1_ncomms9821.pdf
file_size: 1701815
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5597'
pubrep_id: '477'
quality_controlled: '1'
scopus_import: 1
status: public
title: A coherent transcriptional feed-forward motif model for mediating auxin-sensitive
PIN3 expression during lateral root development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1575'
abstract:
- lang: eng
text: The immune response relies on the migration of leukocytes and on their ability
to stop in precise anatomical locations to fulfil their task. How leukocyte migration
and function are coordinated is unknown. Here we show that in immature dendritic
cells, which patrol their environment by engulfing extracellular material, cell
migration and antigen capture are antagonistic. This antagonism results from transient
enrichment of myosin IIA at the cell front, which disrupts the back-to-front gradient
of the motor protein, slowing down locomotion but promoting antigen capture. We
further highlight that myosin IIA enrichment at the cell front requires the MHC
class II-associated invariant chain (Ii). Thus, by controlling myosin IIA localization,
Ii imposes on dendritic cells an intermittent antigen capture behaviour that might
facilitate environment patrolling. We propose that the requirement for myosin
II in both cell migration and specific cell functions may provide a general mechanism
for their coordination in time and space.
acknowledgement: M.C. and M.L.H. were supported by fellowships from the Fondation
pour la Recherche Médicale and the Association pour la Recherche contre le Cancer,
respectively. This work was funded by grants from the City of Paris and the European
Research Council to A.-M.L.-D. (Strapacemi 243103), the Association Nationale pour
la Recherche (ANR-09-PIRI-0027-PCVI) and the InnaBiosanté foundation (Micemico)
to A.-M.L.-D., M.P. and R.V., and the DCBIOL Labex from the French Government (ANR-10-IDEX-0001-02-PSL*
and ANR-11-LABX-0043). The super-resolution SIM microscope was funded through an
ERC Advanced Investigator Grant (250367) to Edith Heard (CNRS UMR3215/Inserm U934,
Institut Curie).
article_number: '7526'
author:
- first_name: Mélanie
full_name: Chabaud, Mélanie
last_name: Chabaud
- first_name: Mélina
full_name: Heuzé, Mélina
last_name: Heuzé
- first_name: Marine
full_name: Bretou, Marine
last_name: Bretou
- first_name: Pablo
full_name: Vargas, Pablo
last_name: Vargas
- first_name: Paolo
full_name: Maiuri, Paolo
last_name: Maiuri
- first_name: Paola
full_name: Solanes, Paola
last_name: Solanes
- first_name: Mathieu
full_name: Maurin, Mathieu
last_name: Maurin
- first_name: Emmanuel
full_name: Terriac, Emmanuel
last_name: Terriac
- first_name: Maël
full_name: Le Berre, Maël
last_name: Le Berre
- first_name: Danielle
full_name: Lankar, Danielle
last_name: Lankar
- first_name: Tristan
full_name: Piolot, Tristan
last_name: Piolot
- first_name: Robert
full_name: Adelstein, Robert
last_name: Adelstein
- first_name: Yingfan
full_name: Zhang, Yingfan
last_name: Zhang
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Jordan
full_name: Jacobelli, Jordan
last_name: Jacobelli
- first_name: Olivier
full_name: Bénichou, Olivier
last_name: Bénichou
- first_name: Raphaël
full_name: Voituriez, Raphaël
last_name: Voituriez
- first_name: Matthieu
full_name: Piel, Matthieu
last_name: Piel
- first_name: Ana
full_name: Lennon Duménil, Ana
last_name: Lennon Duménil
citation:
ama: Chabaud M, Heuzé M, Bretou M, et al. Cell migration and antigen capture are
antagonistic processes coupled by myosin II in dendritic cells. Nature Communications.
2015;6. doi:10.1038/ncomms8526
apa: Chabaud, M., Heuzé, M., Bretou, M., Vargas, P., Maiuri, P., Solanes, P., …
Lennon Duménil, A. (2015). Cell migration and antigen capture are antagonistic
processes coupled by myosin II in dendritic cells. Nature Communications.
Nature Publishing Group. https://doi.org/10.1038/ncomms8526
chicago: Chabaud, Mélanie, Mélina Heuzé, Marine Bretou, Pablo Vargas, Paolo Maiuri,
Paola Solanes, Mathieu Maurin, et al. “Cell Migration and Antigen Capture Are
Antagonistic Processes Coupled by Myosin II in Dendritic Cells.” Nature Communications.
Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms8526.
ieee: M. Chabaud et al., “Cell migration and antigen capture are antagonistic
processes coupled by myosin II in dendritic cells,” Nature Communications,
vol. 6. Nature Publishing Group, 2015.
ista: Chabaud M, Heuzé M, Bretou M, Vargas P, Maiuri P, Solanes P, Maurin M, Terriac
E, Le Berre M, Lankar D, Piolot T, Adelstein R, Zhang Y, Sixt MK, Jacobelli J,
Bénichou O, Voituriez R, Piel M, Lennon Duménil A. 2015. Cell migration and antigen
capture are antagonistic processes coupled by myosin II in dendritic cells. Nature
Communications. 6, 7526.
mla: Chabaud, Mélanie, et al. “Cell Migration and Antigen Capture Are Antagonistic
Processes Coupled by Myosin II in Dendritic Cells.” Nature Communications,
vol. 6, 7526, Nature Publishing Group, 2015, doi:10.1038/ncomms8526.
short: M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin,
E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt,
J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications
6 (2015).
date_created: 2018-12-11T11:52:48Z
date_published: 2015-06-25T00:00:00Z
date_updated: 2021-01-12T06:51:42Z
day: '25'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1038/ncomms8526
file:
- access_level: open_access
checksum: bae12e86be2adb28253f890b8bba8315
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:58Z
date_updated: 2020-07-14T12:45:02Z
file_id: '4915'
file_name: IST-2016-476-v1+1_ncomms8526.pdf
file_size: 4530215
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5596'
pubrep_id: '476'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cell migration and antigen capture are antagonistic processes coupled by myosin
II in dendritic cells
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1569'
abstract:
- lang: eng
text: Spatial regulation of the plant hormone indole-3-acetic acid (IAA, or auxin)
is essential for plant development. Auxin gradient establishment is mediated by
polarly localized auxin transporters, including PIN-FORMED (PIN) proteins. Their
localization and abundance at the plasma membrane are tightly regulated by endomembrane
machinery, especially the endocytic and recycling pathways mediated by the ADP
ribosylation factor guanine nucleotide exchange factor (ARF-GEF) GNOM. We assessed
the role of the early secretory pathway in establishing PIN1 polarity in Arabidopsis
thaliana by pharmacological and genetic approaches. We identified the compound
endosidin 8 (ES8), which selectively interferes with PIN1 basal polarity without
altering the polarity of apical proteins. ES8 alters the auxin distribution pattern
in the root and induces a strong developmental phenotype, including reduced root
length. The ARF-GEF- defective mutants gnom-like 1 ( gnl1-1) and gnom ( van7)
are significantly resistant to ES8. The compound does not affect recycling or
vacuolar trafficking of PIN1 but leads to its intracellular accumulation, resulting
in loss of PIN1 basal polarity at the plasma membrane. Our data confirm a role
for GNOM in endoplasmic reticulum (ER) - Golgi trafficking and reveal that a GNL1/GNOM-mediated
early secretory pathway selectively regulates PIN1 basal polarity establishment
in a manner essential for normal plant development.
acknowledgement: 'This work was supported by Vetenskapsrådet and Vinnova (Verket för
Innovationssystemet) (S.M.D., T.V., M.Ł., and S.R.), Knut och Alice Wallenbergs
Stiftelse (S.M.D., A.R., and C.V.), Kempestiftelserna (A.H. and Q.M.), Carl Tryggers
Stiftelse för Vetenskaplig Forskning (Q.M.), European Research Council Grant ERC-2011-StG-20101109-PSDP
(to J.F.), US Department of Energy Grant DE-FG02-02ER15295 (to N.V.R.), and National
Science Foundation Grant MCB-0817916 (to N.V.R. and G.R.H.). '
author:
- first_name: Siamsa
full_name: Doyle, Siamsa
last_name: Doyle
- first_name: Ash
full_name: Haegera, Ash
last_name: Haegera
- first_name: Thomas
full_name: Vain, Thomas
last_name: Vain
- first_name: Adeline
full_name: Rigala, Adeline
last_name: Rigala
- first_name: Corrado
full_name: Viotti, Corrado
last_name: Viotti
- first_name: Małgorzata
full_name: Łangowskaa, Małgorzata
last_name: Łangowskaa
- first_name: Qian
full_name: Maa, Qian
last_name: Maa
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Natasha
full_name: Raikhel, Natasha
last_name: Raikhel
- first_name: Glenn
full_name: Hickse, Glenn
last_name: Hickse
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
citation:
ama: Doyle S, Haegera A, Vain T, et al. An early secretory pathway mediated by gnom-like
1 and gnom is essential for basal polarity establishment in Arabidopsis thaliana.
PNAS. 2015;112(7):E806-E815. doi:10.1073/pnas.1424856112
apa: Doyle, S., Haegera, A., Vain, T., Rigala, A., Viotti, C., Łangowskaa, M., …
Robert, S. (2015). An early secretory pathway mediated by gnom-like 1 and gnom
is essential for basal polarity establishment in Arabidopsis thaliana. PNAS.
National Academy of Sciences. https://doi.org/10.1073/pnas.1424856112
chicago: Doyle, Siamsa, Ash Haegera, Thomas Vain, Adeline Rigala, Corrado Viotti,
Małgorzata Łangowskaa, Qian Maa, et al. “An Early Secretory Pathway Mediated by
Gnom-like 1 and Gnom Is Essential for Basal Polarity Establishment in Arabidopsis
Thaliana.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1424856112.
ieee: S. Doyle et al., “An early secretory pathway mediated by gnom-like
1 and gnom is essential for basal polarity establishment in Arabidopsis thaliana,”
PNAS, vol. 112, no. 7. National Academy of Sciences, pp. E806–E815, 2015.
ista: Doyle S, Haegera A, Vain T, Rigala A, Viotti C, Łangowskaa M, Maa Q, Friml
J, Raikhel N, Hickse G, Robert S. 2015. An early secretory pathway mediated by
gnom-like 1 and gnom is essential for basal polarity establishment in Arabidopsis
thaliana. PNAS. 112(7), E806–E815.
mla: Doyle, Siamsa, et al. “An Early Secretory Pathway Mediated by Gnom-like 1 and
Gnom Is Essential for Basal Polarity Establishment in Arabidopsis Thaliana.” PNAS,
vol. 112, no. 7, National Academy of Sciences, 2015, pp. E806–15, doi:10.1073/pnas.1424856112.
short: S. Doyle, A. Haegera, T. Vain, A. Rigala, C. Viotti, M. Łangowskaa, Q. Maa,
J. Friml, N. Raikhel, G. Hickse, S. Robert, PNAS 112 (2015) E806–E815.
date_created: 2018-12-11T11:52:46Z
date_published: 2015-02-17T00:00:00Z
date_updated: 2021-01-12T06:51:39Z
day: '17'
department:
- _id: JiFr
doi: 10.1073/pnas.1424856112
ec_funded: 1
intvolume: ' 112'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343110/
month: '02'
oa: 1
oa_version: Published Version
page: E806 - E815
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5602'
quality_controlled: '1'
scopus_import: 1
status: public
title: An early secretory pathway mediated by gnom-like 1 and gnom is essential for
basal polarity establishment in Arabidopsis thaliana
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1570'
abstract:
- lang: eng
text: Grounding autonomous behavior in the nervous system is a fundamental challenge
for neuroscience. In particular, self-organized behavioral development provides
more questions than answers. Are there special functional units for curiosity,
motivation, and creativity? This paper argues that these features can be grounded
in synaptic plasticity itself, without requiring any higher-level constructs.
We propose differential extrinsic plasticity (DEP) as a new synaptic rule for
self-learning systems and apply it to a number of complex robotic systems as a
test case. Without specifying any purpose or goal, seemingly purposeful and adaptive
rhythmic behavior is developed, displaying a certain level of sensorimotor intelligence.
These surprising results require no systemspecific modifications of the DEP rule.
They rather arise from the underlying mechanism of spontaneous symmetry breaking,which
is due to the tight brain body environment coupling. The new synaptic rule is
biologically plausible and would be an interesting target for neurobiological
investigation. We also argue that this neuronal mechanism may have been a catalyst
in natural evolution.
author:
- first_name: Ralf
full_name: Der, Ralf
last_name: Der
- first_name: Georg S
full_name: Martius, Georg S
id: 3A276B68-F248-11E8-B48F-1D18A9856A87
last_name: Martius
citation:
ama: Der R, Martius GS. Novel plasticity rule can explain the development of sensorimotor
intelligence. PNAS. 2015;112(45):E6224-E6232. doi:10.1073/pnas.1508400112
apa: Der, R., & Martius, G. S. (2015). Novel plasticity rule can explain the
development of sensorimotor intelligence. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.1508400112
chicago: Der, Ralf, and Georg S Martius. “Novel Plasticity Rule Can Explain the
Development of Sensorimotor Intelligence.” PNAS. National Academy of Sciences,
2015. https://doi.org/10.1073/pnas.1508400112.
ieee: R. Der and G. S. Martius, “Novel plasticity rule can explain the development
of sensorimotor intelligence,” PNAS, vol. 112, no. 45. National Academy
of Sciences, pp. E6224–E6232, 2015.
ista: Der R, Martius GS. 2015. Novel plasticity rule can explain the development
of sensorimotor intelligence. PNAS. 112(45), E6224–E6232.
mla: Der, Ralf, and Georg S. Martius. “Novel Plasticity Rule Can Explain the Development
of Sensorimotor Intelligence.” PNAS, vol. 112, no. 45, National Academy
of Sciences, 2015, pp. E6224–32, doi:10.1073/pnas.1508400112.
short: R. Der, G.S. Martius, PNAS 112 (2015) E6224–E6232.
date_created: 2018-12-11T11:52:47Z
date_published: 2015-11-10T00:00:00Z
date_updated: 2021-01-12T06:51:40Z
day: '10'
department:
- _id: ChLa
- _id: GaTk
doi: 10.1073/pnas.1508400112
ec_funded: 1
external_id:
pmid:
- '26504200'
intvolume: ' 112'
issue: '45'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653169/
month: '11'
oa: 1
oa_version: Submitted Version
page: E6224 - E6232
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5601'
quality_controlled: '1'
scopus_import: 1
status: public
title: Novel plasticity rule can explain the development of sensorimotor intelligence
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1572'
abstract:
- lang: eng
text: "We consider the quantum ferromagnetic Heisenberg model in three dimensions,
for all spins S ≥ 1/2. We rigorously prove the validity of the spin-wave approximation
for the excitation spectrum, at the level of the first non-trivial contribution
to the free energy at low temperatures. Our proof comes with explicit, constructive
upper and lower bounds on the error term. It uses in an essential way the bosonic
formulation of the model in terms of the Holstein-Primakoff representation. In
this language, the model describes interacting bosons with a hard-core on-site
repulsion and a nearest-neighbor attraction. This attractive interaction makes
the lower bound on the free energy particularly tricky: the key idea there is
to prove a differential inequality for the two-particle density, which is thereby
shown to be smaller than the probability density of a suitably weighted two-particle
random process on the lattice.\r\n"
author:
- first_name: Michele
full_name: Correggi, Michele
last_name: Correggi
- first_name: Alessandro
full_name: Giuliani, Alessandro
last_name: Giuliani
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Correggi M, Giuliani A, Seiringer R. Validity of the spin-wave approximation
for the free energy of the Heisenberg ferromagnet. Communications in Mathematical
Physics. 2015;339(1):279-307. doi:10.1007/s00220-015-2402-0
apa: Correggi, M., Giuliani, A., & Seiringer, R. (2015). Validity of the spin-wave
approximation for the free energy of the Heisenberg ferromagnet. Communications
in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-015-2402-0
chicago: Correggi, Michele, Alessandro Giuliani, and Robert Seiringer. “Validity
of the Spin-Wave Approximation for the Free Energy of the Heisenberg Ferromagnet.”
Communications in Mathematical Physics. Springer, 2015. https://doi.org/10.1007/s00220-015-2402-0.
ieee: M. Correggi, A. Giuliani, and R. Seiringer, “Validity of the spin-wave approximation
for the free energy of the Heisenberg ferromagnet,” Communications in Mathematical
Physics, vol. 339, no. 1. Springer, pp. 279–307, 2015.
ista: Correggi M, Giuliani A, Seiringer R. 2015. Validity of the spin-wave approximation
for the free energy of the Heisenberg ferromagnet. Communications in Mathematical
Physics. 339(1), 279–307.
mla: Correggi, Michele, et al. “Validity of the Spin-Wave Approximation for the
Free Energy of the Heisenberg Ferromagnet.” Communications in Mathematical
Physics, vol. 339, no. 1, Springer, 2015, pp. 279–307, doi:10.1007/s00220-015-2402-0.
short: M. Correggi, A. Giuliani, R. Seiringer, Communications in Mathematical Physics
339 (2015) 279–307.
date_created: 2018-12-11T11:52:47Z
date_published: 2015-06-23T00:00:00Z
date_updated: 2021-01-12T06:51:41Z
day: '23'
department:
- _id: RoSe
doi: 10.1007/s00220-015-2402-0
intvolume: ' 339'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1312.7873
month: '06'
oa: 1
oa_version: Preprint
page: 279 - 307
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '5599'
quality_controlled: '1'
scopus_import: 1
status: public
title: Validity of the spin-wave approximation for the free energy of the Heisenberg
ferromagnet
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 339
year: '2015'
...
---
_id: '1573'
abstract:
- lang: eng
text: We present a new, simpler proof of the unconditional uniqueness of solutions
to the cubic Gross-Pitaevskii hierarchy in ℝ3. One of the main tools in our analysis
is the quantum de Finetti theorem. Our uniqueness result is equivalent to the
one established in the celebrated works of Erdos, Schlein, and Yau.
author:
- first_name: Thomas
full_name: Chen, Thomas
last_name: Chen
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Nataša
full_name: Pavlović, Nataša
last_name: Pavlović
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Chen T, Hainzl C, Pavlović N, Seiringer R. Unconditional uniqueness for the
cubic gross pitaevskii hierarchy via quantum de finetti. Communications on
Pure and Applied Mathematics. 2015;68(10):1845-1884. doi:10.1002/cpa.21552
apa: Chen, T., Hainzl, C., Pavlović, N., & Seiringer, R. (2015). Unconditional
uniqueness for the cubic gross pitaevskii hierarchy via quantum de finetti. Communications
on Pure and Applied Mathematics. Wiley. https://doi.org/10.1002/cpa.21552
chicago: Chen, Thomas, Christian Hainzl, Nataša Pavlović, and Robert Seiringer.
“Unconditional Uniqueness for the Cubic Gross Pitaevskii Hierarchy via Quantum
de Finetti.” Communications on Pure and Applied Mathematics. Wiley, 2015.
https://doi.org/10.1002/cpa.21552.
ieee: T. Chen, C. Hainzl, N. Pavlović, and R. Seiringer, “Unconditional uniqueness
for the cubic gross pitaevskii hierarchy via quantum de finetti,” Communications
on Pure and Applied Mathematics, vol. 68, no. 10. Wiley, pp. 1845–1884, 2015.
ista: Chen T, Hainzl C, Pavlović N, Seiringer R. 2015. Unconditional uniqueness
for the cubic gross pitaevskii hierarchy via quantum de finetti. Communications
on Pure and Applied Mathematics. 68(10), 1845–1884.
mla: Chen, Thomas, et al. “Unconditional Uniqueness for the Cubic Gross Pitaevskii
Hierarchy via Quantum de Finetti.” Communications on Pure and Applied Mathematics,
vol. 68, no. 10, Wiley, 2015, pp. 1845–84, doi:10.1002/cpa.21552.
short: T. Chen, C. Hainzl, N. Pavlović, R. Seiringer, Communications on Pure and
Applied Mathematics 68 (2015) 1845–1884.
date_created: 2018-12-11T11:52:48Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2021-01-12T06:51:41Z
day: '01'
department:
- _id: RoSe
doi: 10.1002/cpa.21552
intvolume: ' 68'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.3168
month: '10'
oa: 1
oa_version: Preprint
page: 1845 - 1884
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication: Communications on Pure and Applied Mathematics
publication_status: published
publisher: Wiley
publist_id: '5598'
quality_controlled: '1'
scopus_import: 1
status: public
title: Unconditional uniqueness for the cubic gross pitaevskii hierarchy via quantum
de finetti
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 68
year: '2015'
...
---
_id: '1580'
abstract:
- lang: eng
text: Synapsins (Syns) are an evolutionarily conserved family of presynaptic proteins
crucial for the fine-tuning of synaptic function. A large amount of experimental
evidences has shown that Syns are involved in the development of epileptic phenotypes
and several mutations in Syn genes have been associated with epilepsy in humans
and animal models. Syn mutations induce alterations in circuitry and neurotransmitter
release, differentially affecting excitatory and inhibitory synapses, thus causing
an excitation/inhibition imbalance in network excitability toward hyperexcitability
that may be a determinant with regard to the development of epilepsy. Another
approach to investigate epileptogenic mechanisms is to understand how silencing
Syn affects the cellular behavior of single neurons and is associated with the
hyperexcitable phenotypes observed in epilepsy. Here, we examined the functional
effects of antisense-RNA inhibition of Syn expression on individually identified
and isolated serotonergic cells of the Helix land snail. We found that Helix synapsin
silencing increases cell excitability characterized by a slightly depolarized
resting membrane potential, decreases the rheobase, reduces the threshold for
action potential (AP) firing and increases the mean and instantaneous firing rates,
with respect to control cells. The observed increase of Ca2+ and BK currents in
Syn-silenced cells seems to be related to changes in the shape of the AP waveform.
These currents sustain the faster spiking in Syn-deficient cells by increasing
the after hyperpolarization and limiting the Na+ and Ca2+ channel inactivation
during repetitive firing. This in turn speeds up the depolarization phase by reaching
the AP threshold faster. Our results provide evidence that Syn silencing increases
intrinsic cell excitability associated with increased Ca2+ and Ca2+-dependent
BK currents in the absence of excitatory or inhibitory inputs.
article_processing_charge: No
article_type: original
author:
- first_name: Oscar
full_name: Brenes, Oscar
last_name: Brenes
- first_name: David H
full_name: Vandael, David H
id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
last_name: Vandael
orcid: 0000-0001-7577-1676
- first_name: Emilio
full_name: Carbone, Emilio
last_name: Carbone
- first_name: Pier
full_name: Montarolo, Pier
last_name: Montarolo
- first_name: Mirella
full_name: Ghirardi, Mirella
last_name: Ghirardi
citation:
ama: Brenes O, Vandael DH, Carbone E, Montarolo P, Ghirardi M. Knock-down of synapsin
alters cell excitability and action potential waveform by potentiating BK and
voltage gated Ca2 currents in Helix serotonergic neurons. Neuroscience.
2015;311:430-443. doi:10.1016/j.neuroscience.2015.10.046
apa: Brenes, O., Vandael, D. H., Carbone, E., Montarolo, P., & Ghirardi, M.
(2015). Knock-down of synapsin alters cell excitability and action potential waveform
by potentiating BK and voltage gated Ca2 currents in Helix serotonergic neurons.
Neuroscience. Elsevier. https://doi.org/10.1016/j.neuroscience.2015.10.046
chicago: Brenes, Oscar, David H Vandael, Emilio Carbone, Pier Montarolo, and Mirella
Ghirardi. “Knock-down of Synapsin Alters Cell Excitability and Action Potential
Waveform by Potentiating BK and Voltage Gated Ca2 Currents in Helix Serotonergic
Neurons.” Neuroscience. Elsevier, 2015. https://doi.org/10.1016/j.neuroscience.2015.10.046.
ieee: O. Brenes, D. H. Vandael, E. Carbone, P. Montarolo, and M. Ghirardi, “Knock-down
of synapsin alters cell excitability and action potential waveform by potentiating
BK and voltage gated Ca2 currents in Helix serotonergic neurons,” Neuroscience,
vol. 311. Elsevier, pp. 430–443, 2015.
ista: Brenes O, Vandael DH, Carbone E, Montarolo P, Ghirardi M. 2015. Knock-down
of synapsin alters cell excitability and action potential waveform by potentiating
BK and voltage gated Ca2 currents in Helix serotonergic neurons. Neuroscience.
311, 430–443.
mla: Brenes, Oscar, et al. “Knock-down of Synapsin Alters Cell Excitability and
Action Potential Waveform by Potentiating BK and Voltage Gated Ca2 Currents in
Helix Serotonergic Neurons.” Neuroscience, vol. 311, Elsevier, 2015, pp.
430–43, doi:10.1016/j.neuroscience.2015.10.046.
short: O. Brenes, D.H. Vandael, E. Carbone, P. Montarolo, M. Ghirardi, Neuroscience
311 (2015) 430–443.
date_created: 2018-12-11T11:52:50Z
date_published: 2015-12-17T00:00:00Z
date_updated: 2021-01-12T06:51:44Z
day: '17'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.neuroscience.2015.10.046
file:
- access_level: open_access
checksum: af2c4c994718c7be417eba0dc746aac9
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T06:50:20Z
date_updated: 2020-07-14T12:45:02Z
file_id: '7849'
file_name: 2015_Neuroscience_Brenes.pdf
file_size: 5563015
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 311'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 430 - 443
publication: Neuroscience
publication_status: published
publisher: Elsevier
publist_id: '5591'
quality_controlled: '1'
scopus_import: 1
status: public
title: Knock-down of synapsin alters cell excitability and action potential waveform
by potentiating BK and voltage gated Ca2 currents in Helix serotonergic neurons
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 311
year: '2015'
...
---
_id: '1577'
abstract:
- lang: eng
text: Contrary to the pattern seen in mammalian sex chromosomes, where most Y-linked
genes have X-linked homologs, the Drosophila X and Y chromosomes appear to be
unrelated. Most of the Y-linked genes have autosomal paralogs, so autosome-to-Y
transposition must be the main source of Drosophila Y-linked genes. Here we show
how these genes were acquired. We found a previously unidentified gene (flagrante
delicto Y, FDY) that originated from a recent duplication of the autosomal gene
vig2 to the Y chromosome of Drosophila melanogaster. Four contiguous genes were
duplicated along with vig2, but they became pseudogenes through the accumulation
of deletions and transposable element insertions, whereas FDY remained functional,
acquired testis-specific expression, and now accounts for ∼20% of the vig2-like
mRNA in testis. FDY is absent in the closest relatives of D. melanogaster, and
DNA sequence divergence indicates that the duplication to the Y chromosome occurred
∼2 million years ago. Thus, FDY provides a snapshot of the early stages of the
establishment of a Y-linked gene and demonstrates how the Drosophila Y has been
accumulating autosomal genes.
acknowledgement: "This work was supported by grants from Conselho Nacional de Desenvolvimento
Científico e Tecnológico (CNPq), FAPERJ, and CAPES (to A.B.C.), and National Institutes
of Health Grant R01 GM64590 (to A.G.C. and A.B.C.).\r\nWe thank M. Vibranovski,
C. Bergman, and the Berkeley Drosophila Genome Project for access to unpublished
data; M. Vibranovski, R. Hoskins, S. Celniker, C. Kennedy, J. Carlson, S. Galasinski,
B. Wakimoto, J. Yasuhara, G. Sutton, M. Kuhner, J. Felsenstein, and C. Santos for
help in various steps of the work; and B. Bitner-Mathe, R. Ventura, the members
of the A.B.C. and A.G.C. laboratories, and two reviewers for many valuable comments
on the manuscript."
article_processing_charge: No
article_type: original
author:
- first_name: Antonio
full_name: Carvalho, Antonio
last_name: Carvalho
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Claudia
full_name: Russo, Claudia
last_name: Russo
- first_name: Bonnielin
full_name: Swenor, Bonnielin
last_name: Swenor
- first_name: Andrew
full_name: Clark, Andrew
last_name: Clark
citation:
ama: Carvalho A, Vicoso B, Russo C, Swenor B, Clark A. Birth of a new gene on the
Y chromosome of Drosophila melanogaster. PNAS. 2015;112(40):12450-12455.
doi:10.1073/pnas.1516543112
apa: Carvalho, A., Vicoso, B., Russo, C., Swenor, B., & Clark, A. (2015). Birth
of a new gene on the Y chromosome of Drosophila melanogaster. PNAS. National
Academy of Sciences. https://doi.org/10.1073/pnas.1516543112
chicago: Carvalho, Antonio, Beatriz Vicoso, Claudia Russo, Bonnielin Swenor, and
Andrew Clark. “Birth of a New Gene on the Y Chromosome of Drosophila Melanogaster.”
PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1516543112.
ieee: A. Carvalho, B. Vicoso, C. Russo, B. Swenor, and A. Clark, “Birth of a new
gene on the Y chromosome of Drosophila melanogaster,” PNAS, vol. 112, no.
40. National Academy of Sciences, pp. 12450–12455, 2015.
ista: Carvalho A, Vicoso B, Russo C, Swenor B, Clark A. 2015. Birth of a new gene
on the Y chromosome of Drosophila melanogaster. PNAS. 112(40), 12450–12455.
mla: Carvalho, Antonio, et al. “Birth of a New Gene on the Y Chromosome of Drosophila
Melanogaster.” PNAS, vol. 112, no. 40, National Academy of Sciences, 2015,
pp. 12450–55, doi:10.1073/pnas.1516543112.
short: A. Carvalho, B. Vicoso, C. Russo, B. Swenor, A. Clark, PNAS 112 (2015) 12450–12455.
date_created: 2018-12-11T11:52:49Z
date_published: 2015-10-06T00:00:00Z
date_updated: 2021-01-12T06:51:43Z
day: '06'
department:
- _id: BeVi
doi: 10.1073/pnas.1516543112
external_id:
pmid:
- '26385968'
intvolume: ' 112'
issue: '40'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603513/
month: '10'
oa: 1
oa_version: Published Version
page: 12450 - 12455
pmid: 1
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5594'
quality_controlled: '1'
scopus_import: 1
status: public
title: Birth of a new gene on the Y chromosome of Drosophila melanogaster
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1579'
abstract:
- lang: eng
text: We show that the Galois group of any Schubert problem involving lines in projective
space contains the alternating group. This constitutes the largest family of enumerative
problems whose Galois groups have been largely determined. Using a criterion of
Vakil and a special position argument due to Schubert, our result follows from
a particular inequality among Kostka numbers of two-rowed tableaux. In most cases,
a combinatorial injection proves the inequality. For the remaining cases, we use
the Weyl integral formulas to obtain an integral formula for these Kostka numbers.
This rewrites the inequality as an integral, which we estimate to establish the
inequality.
acknowledgement: "This research was supported in part by NSF grant DMS-915211 and
the Institut Mittag-Leffler.\r\n"
article_processing_charge: No
author:
- first_name: Christopher
full_name: Brooks, Christopher
last_name: Brooks
- first_name: Abraham
full_name: Martin Del Campo Sanchez, Abraham
id: 4CF47F6A-F248-11E8-B48F-1D18A9856A87
last_name: Martin Del Campo Sanchez
- first_name: Frank
full_name: Sottile, Frank
last_name: Sottile
citation:
ama: Brooks C, Martin del Campo Sanchez A, Sottile F. Galois groups of Schubert
problems of lines are at least alternating. Transactions of the American Mathematical
Society. 2015;367(6):4183-4206. doi:10.1090/S0002-9947-2014-06192-8
apa: Brooks, C., Martin del Campo Sanchez, A., & Sottile, F. (2015). Galois
groups of Schubert problems of lines are at least alternating. Transactions
of the American Mathematical Society. American Mathematical Society. https://doi.org/10.1090/S0002-9947-2014-06192-8
chicago: Brooks, Christopher, Abraham Martin del Campo Sanchez, and Frank Sottile.
“Galois Groups of Schubert Problems of Lines Are at Least Alternating.” Transactions
of the American Mathematical Society. American Mathematical Society, 2015.
https://doi.org/10.1090/S0002-9947-2014-06192-8.
ieee: C. Brooks, A. Martin del Campo Sanchez, and F. Sottile, “Galois groups of
Schubert problems of lines are at least alternating,” Transactions of the American
Mathematical Society, vol. 367, no. 6. American Mathematical Society, pp.
4183–4206, 2015.
ista: Brooks C, Martin del Campo Sanchez A, Sottile F. 2015. Galois groups of Schubert
problems of lines are at least alternating. Transactions of the American Mathematical
Society. 367(6), 4183–4206.
mla: Brooks, Christopher, et al. “Galois Groups of Schubert Problems of Lines Are
at Least Alternating.” Transactions of the American Mathematical Society,
vol. 367, no. 6, American Mathematical Society, 2015, pp. 4183–206, doi:10.1090/S0002-9947-2014-06192-8.
short: C. Brooks, A. Martin del Campo Sanchez, F. Sottile, Transactions of the American
Mathematical Society 367 (2015) 4183–4206.
date_created: 2018-12-11T11:52:50Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:51:43Z
day: '01'
department:
- _id: CaUh
doi: 10.1090/S0002-9947-2014-06192-8
intvolume: ' 367'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1207.4280
month: '06'
oa: 1
oa_version: Preprint
page: 4183 - 4206
publication: Transactions of the American Mathematical Society
publication_status: published
publisher: American Mathematical Society
publist_id: '5592'
quality_controlled: '1'
scopus_import: 1
status: public
title: Galois groups of Schubert problems of lines are at least alternating
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 367
year: '2015'
...
---
_id: '1589'
abstract:
- lang: eng
text: We investigate the dynamics of ferrofluidic wavy vortex flows in the counter-rotating
Taylor-Couette system, with a focus on wavy flows with a mixture of the dominant
azimuthal modes. Without external magnetic field flows are stable and pro-grade
with respect to the rotation of the inner cylinder. More complex behaviors can
arise when an axial or a transverse magnetic field is applied. Depending on the
direction and strength of the field, multi-stable wavy states and bifurcations
can occur. We uncover the phenomenon of flow pattern reversal as the strength
of the magnetic field is increased through a critical value. In between the regimes
of pro-grade and retrograde flow rotations, standing waves with zero angular velocities
can emerge. A striking finding is that, under a transverse magnetic field, a second
reversal in the flow pattern direction can occur, where the flow pattern evolves
into pro-grade rotation again from a retrograde state. Flow reversal is relevant
to intriguing phenomena in nature such as geomagnetic reversal. Our results suggest
that, in ferrofluids, flow pattern reversal can be induced by varying a magnetic
field in a controlled manner, which can be realized in laboratory experiments
with potential applications in the development of modern fluid devices.
article_number: '18589'
article_type: original
author:
- first_name: Sebastian
full_name: Altmeyer, Sebastian
id: 2EE67FDC-F248-11E8-B48F-1D18A9856A87
last_name: Altmeyer
orcid: 0000-0001-5964-0203
- first_name: Younghae
full_name: Do, Younghae
last_name: Do
- first_name: Ying
full_name: Lai, Ying
last_name: Lai
citation:
ama: Altmeyer S, Do Y, Lai Y. Magnetic field induced flow pattern reversal in a
ferrofluidic Taylor-Couette system. Scientific Reports. 2015;5. doi:10.1038/srep18589
apa: Altmeyer, S., Do, Y., & Lai, Y. (2015). Magnetic field induced flow pattern
reversal in a ferrofluidic Taylor-Couette system. Scientific Reports. Nature
Publishing Group. https://doi.org/10.1038/srep18589
chicago: Altmeyer, Sebastian, Younghae Do, and Ying Lai. “Magnetic Field Induced
Flow Pattern Reversal in a Ferrofluidic Taylor-Couette System.” Scientific
Reports. Nature Publishing Group, 2015. https://doi.org/10.1038/srep18589.
ieee: S. Altmeyer, Y. Do, and Y. Lai, “Magnetic field induced flow pattern reversal
in a ferrofluidic Taylor-Couette system,” Scientific Reports, vol. 5. Nature
Publishing Group, 2015.
ista: Altmeyer S, Do Y, Lai Y. 2015. Magnetic field induced flow pattern reversal
in a ferrofluidic Taylor-Couette system. Scientific Reports. 5, 18589.
mla: Altmeyer, Sebastian, et al. “Magnetic Field Induced Flow Pattern Reversal in
a Ferrofluidic Taylor-Couette System.” Scientific Reports, vol. 5, 18589,
Nature Publishing Group, 2015, doi:10.1038/srep18589.
short: S. Altmeyer, Y. Do, Y. Lai, Scientific Reports 5 (2015).
date_created: 2018-12-11T11:52:53Z
date_published: 2015-12-21T00:00:00Z
date_updated: 2021-01-12T06:51:48Z
day: '21'
ddc:
- '530'
- '540'
department:
- _id: BjHo
doi: 10.1038/srep18589
file:
- access_level: open_access
checksum: 927e151674347661ce36eae2818dafdc
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:49Z
date_updated: 2020-07-14T12:45:03Z
file_id: '5036'
file_name: IST-2016-472-v1+1_srep18589.pdf
file_size: 2771236
relation: main_file
file_date_updated: 2020-07-14T12:45:03Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '5582'
pubrep_id: '472'
quality_controlled: '1'
scopus_import: 1
status: public
title: Magnetic field induced flow pattern reversal in a ferrofluidic Taylor-Couette
system
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2015'
...
---
_id: '1584'
abstract:
- lang: eng
text: We investigate weighted straight skeletons from a geometric, graph-theoretical,
and combinatorial point of view. We start with a thorough definition and shed
light on some ambiguity issues in the procedural definition. We investigate the
geometry, combinatorics, and topology of faces and the roof model, and we discuss
in which cases a weighted straight skeleton is connected. Finally, we show that
the weighted straight skeleton of even a simple polygon may be non-planar and
may contain cycles, and we discuss under which restrictions on the weights and/or
the input polygon the weighted straight skeleton still behaves similar to its
unweighted counterpart. In particular, we obtain a non-procedural description
and a linear-time construction algorithm for the straight skeleton of strictly
convex polygons with arbitrary weights.
author:
- first_name: Therese
full_name: Biedl, Therese
last_name: Biedl
- first_name: Martin
full_name: Held, Martin
last_name: Held
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Dominik
full_name: Kaaser, Dominik
last_name: Kaaser
- first_name: Peter
full_name: Palfrader, Peter
last_name: Palfrader
citation:
ama: 'Biedl T, Held M, Huber S, Kaaser D, Palfrader P. Reprint of: Weighted straight
skeletons in the plane. Computational Geometry: Theory and Applications.
2015;48(5):429-442. doi:10.1016/j.comgeo.2015.01.004'
apa: 'Biedl, T., Held, M., Huber, S., Kaaser, D., & Palfrader, P. (2015). Reprint
of: Weighted straight skeletons in the plane. Computational Geometry: Theory
and Applications. Elsevier. https://doi.org/10.1016/j.comgeo.2015.01.004'
chicago: 'Biedl, Therese, Martin Held, Stefan Huber, Dominik Kaaser, and Peter Palfrader.
“Reprint of: Weighted Straight Skeletons in the Plane.” Computational Geometry:
Theory and Applications. Elsevier, 2015. https://doi.org/10.1016/j.comgeo.2015.01.004.'
ieee: 'T. Biedl, M. Held, S. Huber, D. Kaaser, and P. Palfrader, “Reprint of: Weighted
straight skeletons in the plane,” Computational Geometry: Theory and Applications,
vol. 48, no. 5. Elsevier, pp. 429–442, 2015.'
ista: 'Biedl T, Held M, Huber S, Kaaser D, Palfrader P. 2015. Reprint of: Weighted
straight skeletons in the plane. Computational Geometry: Theory and Applications.
48(5), 429–442.'
mla: 'Biedl, Therese, et al. “Reprint of: Weighted Straight Skeletons in the Plane.”
Computational Geometry: Theory and Applications, vol. 48, no. 5, Elsevier,
2015, pp. 429–42, doi:10.1016/j.comgeo.2015.01.004.'
short: 'T. Biedl, M. Held, S. Huber, D. Kaaser, P. Palfrader, Computational Geometry:
Theory and Applications 48 (2015) 429–442.'
date_created: 2018-12-11T11:52:51Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-23T10:05:22Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1016/j.comgeo.2015.01.004
file:
- access_level: open_access
checksum: 5b33719a86f7f4c8e5dc62c1b6893f49
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:36Z
date_updated: 2020-07-14T12:45:03Z
file_id: '5292'
file_name: IST-2016-475-v1+1_1-s2.0-S092577211500005X-main.pdf
file_size: 508379
relation: main_file
file_date_updated: 2020-07-14T12:45:03Z
has_accepted_license: '1'
intvolume: ' 48'
issue: '5'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 429 - 442
publication: 'Computational Geometry: Theory and Applications'
publication_status: published
publisher: Elsevier
publist_id: '5587'
pubrep_id: '475'
quality_controlled: '1'
related_material:
record:
- id: '1582'
relation: other
status: public
scopus_import: 1
status: public
title: 'Reprint of: Weighted straight skeletons in the plane'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2015'
...
---
_id: '1582'
abstract:
- lang: eng
text: We investigate weighted straight skeletons from a geometric, graph-theoretical,
and combinatorial point of view. We start with a thorough definition and shed
light on some ambiguity issues in the procedural definition. We investigate the
geometry, combinatorics, and topology of faces and the roof model, and we discuss
in which cases a weighted straight skeleton is connected. Finally, we show that
the weighted straight skeleton of even a simple polygon may be non-planar and
may contain cycles, and we discuss under which restrictions on the weights and/or
the input polygon the weighted straight skeleton still behaves similar to its
unweighted counterpart. In particular, we obtain a non-procedural description
and a linear-time construction algorithm for the straight skeleton of strictly
convex polygons with arbitrary weights.
author:
- first_name: Therese
full_name: Biedl, Therese
last_name: Biedl
- first_name: Martin
full_name: Held, Martin
last_name: Held
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Dominik
full_name: Kaaser, Dominik
last_name: Kaaser
- first_name: Peter
full_name: Palfrader, Peter
last_name: Palfrader
citation:
ama: 'Biedl T, Held M, Huber S, Kaaser D, Palfrader P. Weighted straight skeletons
in the plane. Computational Geometry: Theory and Applications. 2015;48(2):120-133.
doi:10.1016/j.comgeo.2014.08.006'
apa: 'Biedl, T., Held, M., Huber, S., Kaaser, D., & Palfrader, P. (2015). Weighted
straight skeletons in the plane. Computational Geometry: Theory and Applications.
Elsevier. https://doi.org/10.1016/j.comgeo.2014.08.006'
chicago: 'Biedl, Therese, Martin Held, Stefan Huber, Dominik Kaaser, and Peter Palfrader.
“Weighted Straight Skeletons in the Plane.” Computational Geometry: Theory
and Applications. Elsevier, 2015. https://doi.org/10.1016/j.comgeo.2014.08.006.'
ieee: 'T. Biedl, M. Held, S. Huber, D. Kaaser, and P. Palfrader, “Weighted straight
skeletons in the plane,” Computational Geometry: Theory and Applications,
vol. 48, no. 2. Elsevier, pp. 120–133, 2015.'
ista: 'Biedl T, Held M, Huber S, Kaaser D, Palfrader P. 2015. Weighted straight
skeletons in the plane. Computational Geometry: Theory and Applications. 48(2),
120–133.'
mla: 'Biedl, Therese, et al. “Weighted Straight Skeletons in the Plane.” Computational
Geometry: Theory and Applications, vol. 48, no. 2, Elsevier, 2015, pp. 120–33,
doi:10.1016/j.comgeo.2014.08.006.'
short: 'T. Biedl, M. Held, S. Huber, D. Kaaser, P. Palfrader, Computational Geometry:
Theory and Applications 48 (2015) 120–133.'
date_created: 2018-12-11T11:52:51Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2023-02-23T10:05:27Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1016/j.comgeo.2014.08.006
file:
- access_level: open_access
checksum: c1ef67f6ec925e12f73a96b8fe285ab4
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:28Z
date_updated: 2020-07-14T12:45:02Z
file_id: '5215'
file_name: IST-2016-474-v1+1_1-s2.0-S0925772114000807-main.pdf
file_size: 505987
relation: main_file
file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 48'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 120 - 133
publication: 'Computational Geometry: Theory and Applications'
publication_status: published
publisher: Elsevier
publist_id: '5589'
pubrep_id: '474'
quality_controlled: '1'
related_material:
record:
- id: '1584'
relation: other
status: public
scopus_import: 1
status: public
title: Weighted straight skeletons in the plane
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2015'
...
---
_id: '1583'
abstract:
- lang: eng
text: We study the characteristics of straight skeletons of monotone polygonal chains
and use them to devise an algorithm for computing positively weighted straight
skeletons of monotone polygons. Our algorithm runs in O(nlogn) time and O(n) space,
where n denotes the number of vertices of the polygon.
author:
- first_name: Therese
full_name: Biedl, Therese
last_name: Biedl
- first_name: Martin
full_name: Held, Martin
last_name: Held
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Dominik
full_name: Kaaser, Dominik
last_name: Kaaser
- first_name: Peter
full_name: Palfrader, Peter
last_name: Palfrader
citation:
ama: Biedl T, Held M, Huber S, Kaaser D, Palfrader P. A simple algorithm for computing
positively weighted straight skeletons of monotone polygons. Information Processing
Letters. 2015;115(2):243-247. doi:10.1016/j.ipl.2014.09.021
apa: Biedl, T., Held, M., Huber, S., Kaaser, D., & Palfrader, P. (2015). A simple
algorithm for computing positively weighted straight skeletons of monotone polygons.
Information Processing Letters. Elsevier. https://doi.org/10.1016/j.ipl.2014.09.021
chicago: Biedl, Therese, Martin Held, Stefan Huber, Dominik Kaaser, and Peter Palfrader.
“A Simple Algorithm for Computing Positively Weighted Straight Skeletons of Monotone
Polygons.” Information Processing Letters. Elsevier, 2015. https://doi.org/10.1016/j.ipl.2014.09.021.
ieee: T. Biedl, M. Held, S. Huber, D. Kaaser, and P. Palfrader, “A simple algorithm
for computing positively weighted straight skeletons of monotone polygons,” Information
Processing Letters, vol. 115, no. 2. Elsevier, pp. 243–247, 2015.
ista: Biedl T, Held M, Huber S, Kaaser D, Palfrader P. 2015. A simple algorithm
for computing positively weighted straight skeletons of monotone polygons. Information
Processing Letters. 115(2), 243–247.
mla: Biedl, Therese, et al. “A Simple Algorithm for Computing Positively Weighted
Straight Skeletons of Monotone Polygons.” Information Processing Letters,
vol. 115, no. 2, Elsevier, 2015, pp. 243–47, doi:10.1016/j.ipl.2014.09.021.
short: T. Biedl, M. Held, S. Huber, D. Kaaser, P. Palfrader, Information Processing
Letters 115 (2015) 243–247.
date_created: 2018-12-11T11:52:51Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:45Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1016/j.ipl.2014.09.021
file:
- access_level: open_access
checksum: 2779a648610c9b5c86d0b51a62816d23
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:45Z
date_updated: 2020-07-14T12:45:03Z
file_id: '5367'
file_name: IST-2016-473-v1+1_1-s2.0-S0020019014001987-main.pdf
file_size: 270137
relation: main_file
file_date_updated: 2020-07-14T12:45:03Z
has_accepted_license: '1'
intvolume: ' 115'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 243 - 247
publication: Information Processing Letters
publication_status: published
publisher: Elsevier
publist_id: '5588'
pubrep_id: '473'
quality_controlled: '1'
scopus_import: 1
status: public
title: A simple algorithm for computing positively weighted straight skeletons of
monotone polygons
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2015'
...
---
_id: '1587'
abstract:
- lang: eng
text: We investigate the quantum interference shifts between energetically close
states, where the state structure is observed by laser spectroscopy. We report
a compact and analytical expression that models the quantum interference induced
shift for any admixture of circular polarization of the incident laser and angle
of observation. An experimental scenario free of quantum interference can thus
be predicted with this formula. Although this study is exemplified here for muonic
deuterium, it can be applied to any other laser spectroscopy measurement of ns-n′p
frequencies of a nonrelativistic atomic system, via an ns→n′p→n′′s scheme.
article_number: '062506'
article_processing_charge: No
article_type: original
author:
- first_name: Pedro
full_name: Amaro, Pedro
last_name: Amaro
- first_name: Filippo
full_name: Fratini, Filippo
last_name: Fratini
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: Aldo
full_name: Antognini, Aldo
last_name: Antognini
- first_name: Paul
full_name: Indelicato, Paul
last_name: Indelicato
- first_name: Randolf
full_name: Pohl, Randolf
last_name: Pohl
- first_name: José
full_name: Santos, José
last_name: Santos
citation:
ama: Amaro P, Fratini F, Safari L, et al. Quantum interference shifts in laser spectroscopy
with elliptical polarization. Physical Review A - Atomic, Molecular, and Optical
Physics. 2015;92(6). doi:10.1103/PhysRevA.92.062506
apa: Amaro, P., Fratini, F., Safari, L., Antognini, A., Indelicato, P., Pohl, R.,
& Santos, J. (2015). Quantum interference shifts in laser spectroscopy with
elliptical polarization. Physical Review A - Atomic, Molecular, and Optical
Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.92.062506
chicago: Amaro, Pedro, Filippo Fratini, Laleh Safari, Aldo Antognini, Paul Indelicato,
Randolf Pohl, and José Santos. “Quantum Interference Shifts in Laser Spectroscopy
with Elliptical Polarization.” Physical Review A - Atomic, Molecular, and Optical
Physics. American Physical Society, 2015. https://doi.org/10.1103/PhysRevA.92.062506.
ieee: P. Amaro et al., “Quantum interference shifts in laser spectroscopy
with elliptical polarization,” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 92, no. 6. American Physical Society, 2015.
ista: Amaro P, Fratini F, Safari L, Antognini A, Indelicato P, Pohl R, Santos J.
2015. Quantum interference shifts in laser spectroscopy with elliptical polarization.
Physical Review A - Atomic, Molecular, and Optical Physics. 92(6), 062506.
mla: Amaro, Pedro, et al. “Quantum Interference Shifts in Laser Spectroscopy with
Elliptical Polarization.” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 92, no. 6, 062506, American Physical Society, 2015, doi:10.1103/PhysRevA.92.062506.
short: P. Amaro, F. Fratini, L. Safari, A. Antognini, P. Indelicato, R. Pohl, J.
Santos, Physical Review A - Atomic, Molecular, and Optical Physics 92 (2015).
date_created: 2018-12-11T11:52:53Z
date_published: 2015-12-31T00:00:00Z
date_updated: 2021-01-12T06:51:47Z
day: '31'
department:
- _id: MiLe
doi: 10.1103/PhysRevA.92.062506
ec_funded: 1
external_id:
arxiv:
- '1511.03585'
intvolume: ' 92'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1511.03585
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '5584'
quality_controlled: '1'
scopus_import: 1
status: public
title: Quantum interference shifts in laser spectroscopy with elliptical polarization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 92
year: '2015'
...
---
_id: '1593'
abstract:
- lang: eng
text: 'Plants are sessile organisms that are permanently restricted to their site
of germination. To compensate for their lack of mobility, plants evolved unique
mechanisms enabling them to rapidly react to ever changing environmental conditions
and flexibly adapt their postembryonic developmental program. A prominent demonstration
of this developmental plasticity is their ability to bend organs in order to reach
the position most optimal for growth and utilization of light, nutrients, and
other resources. Shortly after germination, dicotyledonous seedlings form a bended
structure, the so-called apical hook, to protect the delicate shoot meristem and
cotyledons from damage when penetrating through the soil. Upon perception of a
light stimulus, the apical hook rapidly opens and the photomorphogenic developmental
program is activated. After germination, plant organs are able to align their
growth with the light source and adopt the most favorable orientation through
bending, in a process named phototropism. On the other hand, when roots and shoots
are diverted from their upright orientation, they immediately detect a change
in the gravity vector and bend to maintain a vertical growth direction. Noteworthy,
despite the diversity of external stimuli perceived by different plant organs,
all plant tropic movements share a common mechanistic basis: differential cell
growth. In our review, we will discuss the molecular principles underlying various
tropic responses with the focus on mechanisms mediating the perception of external
signals, transduction cascades and downstream responses that regulate differential
cell growth and consequently, organ bending. In particular, we highlight common
and specific features of regulatory pathways in control of the bending of organs
and a role for the plant hormone auxin as a key regulatory component.'
author:
- first_name: Petra
full_name: Žádníková, Petra
last_name: Žádníková
- first_name: Dajo
full_name: Smet, Dajo
last_name: Smet
- first_name: Qiang
full_name: Zhu, Qiang
id: 40A4B9E6-F248-11E8-B48F-1D18A9856A87
last_name: Zhu
- first_name: Dominique
full_name: Van Der Straeten, Dominique
last_name: Van Der Straeten
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: 'Žádníková P, Smet D, Zhu Q, Van Der Straeten D, Benková E. Strategies of seedlings
to overcome their sessile nature: Auxin in mobility control. Frontiers in Plant
Science. 2015;6(4). doi:10.3389/fpls.2015.00218'
apa: 'Žádníková, P., Smet, D., Zhu, Q., Van Der Straeten, D., & Benková, E.
(2015). Strategies of seedlings to overcome their sessile nature: Auxin in mobility
control. Frontiers in Plant Science. Frontiers Research Foundation. https://doi.org/10.3389/fpls.2015.00218'
chicago: 'Žádníková, Petra, Dajo Smet, Qiang Zhu, Dominique Van Der Straeten, and
Eva Benková. “Strategies of Seedlings to Overcome Their Sessile Nature: Auxin
in Mobility Control.” Frontiers in Plant Science. Frontiers Research Foundation,
2015. https://doi.org/10.3389/fpls.2015.00218.'
ieee: 'P. Žádníková, D. Smet, Q. Zhu, D. Van Der Straeten, and E. Benková, “Strategies
of seedlings to overcome their sessile nature: Auxin in mobility control,” Frontiers
in Plant Science, vol. 6, no. 4. Frontiers Research Foundation, 2015.'
ista: 'Žádníková P, Smet D, Zhu Q, Van Der Straeten D, Benková E. 2015. Strategies
of seedlings to overcome their sessile nature: Auxin in mobility control. Frontiers
in Plant Science. 6(4).'
mla: 'Žádníková, Petra, et al. “Strategies of Seedlings to Overcome Their Sessile
Nature: Auxin in Mobility Control.” Frontiers in Plant Science, vol. 6,
no. 4, Frontiers Research Foundation, 2015, doi:10.3389/fpls.2015.00218.'
short: P. Žádníková, D. Smet, Q. Zhu, D. Van Der Straeten, E. Benková, Frontiers
in Plant Science 6 (2015).
date_created: 2018-12-11T11:52:55Z
date_published: 2015-04-14T00:00:00Z
date_updated: 2021-01-12T06:51:50Z
day: '14'
ddc:
- '570'
department:
- _id: EvBe
doi: 10.3389/fpls.2015.00218
ec_funded: 1
file:
- access_level: open_access
checksum: c454d642e18dfa86820b97a86cd6d3cc
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:23Z
date_updated: 2020-07-14T12:45:03Z
file_id: '5142'
file_name: IST-2016-471-v1+1_fpls-06-00218.pdf
file_size: 965690
relation: main_file
file_date_updated: 2020-07-14T12:45:03Z
has_accepted_license: '1'
intvolume: ' 6'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Frontiers in Plant Science
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '5578'
pubrep_id: '471'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Strategies of seedlings to overcome their sessile nature: Auxin in mobility
control'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1595'
abstract:
- lang: eng
text: 'A drawing of a graph G is radial if the vertices of G are placed on concentric
circles C1, . . . , Ck with common center c, and edges are drawn radially: every
edge intersects every circle centered at c at most once. G is radial planar if
it has a radial embedding, that is, a crossing- free radial drawing. If the vertices
of G are ordered or partitioned into ordered levels (as they are for leveled graphs),
we require that the assignment of vertices to circles corresponds to the given
ordering or leveling. We show that a graph G is radial planar if G has a radial
drawing in which every two edges cross an even number of times; the radial embedding
has the same leveling as the radial drawing. In other words, we establish the
weak variant of the Hanani-Tutte theorem for radial planarity. This generalizes
a result by Pach and Tóth.'
acknowledgement: The research leading to these results has received funding from the
People Programme (Marie Curie Actions) of the European Union’s Seventh Framework
Programme (FP7/2007-2013) under REA grant agreement no [291734].
alternative_title:
- LNCS
author:
- first_name: Radoslav
full_name: Fulek, Radoslav
id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
last_name: Fulek
orcid: 0000-0001-8485-1774
- first_name: Michael
full_name: Pelsmajer, Michael
last_name: Pelsmajer
- first_name: Marcus
full_name: Schaefer, Marcus
last_name: Schaefer
citation:
ama: 'Fulek R, Pelsmajer M, Schaefer M. Hanani-Tutte for radial planarity. In: Vol
9411. Springer; 2015:99-110. doi:10.1007/978-3-319-27261-0_9'
apa: 'Fulek, R., Pelsmajer, M., & Schaefer, M. (2015). Hanani-Tutte for radial
planarity (Vol. 9411, pp. 99–110). Presented at the GD: Graph Drawing and Network
Visualization, Los Angeles, CA, USA: Springer. https://doi.org/10.1007/978-3-319-27261-0_9'
chicago: Fulek, Radoslav, Michael Pelsmajer, and Marcus Schaefer. “Hanani-Tutte
for Radial Planarity,” 9411:99–110. Springer, 2015. https://doi.org/10.1007/978-3-319-27261-0_9.
ieee: 'R. Fulek, M. Pelsmajer, and M. Schaefer, “Hanani-Tutte for radial planarity,”
presented at the GD: Graph Drawing and Network Visualization, Los Angeles, CA,
USA, 2015, vol. 9411, pp. 99–110.'
ista: 'Fulek R, Pelsmajer M, Schaefer M. 2015. Hanani-Tutte for radial planarity.
GD: Graph Drawing and Network Visualization, LNCS, vol. 9411, 99–110.'
mla: Fulek, Radoslav, et al. Hanani-Tutte for Radial Planarity. Vol. 9411,
Springer, 2015, pp. 99–110, doi:10.1007/978-3-319-27261-0_9.
short: R. Fulek, M. Pelsmajer, M. Schaefer, in:, Springer, 2015, pp. 99–110.
conference:
end_date: 2015-09-26
location: Los Angeles, CA, USA
name: 'GD: Graph Drawing and Network Visualization'
start_date: 2015-09-24
date_created: 2018-12-11T11:52:55Z
date_published: 2015-11-27T00:00:00Z
date_updated: 2023-02-21T16:23:36Z
day: '27'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1007/978-3-319-27261-0_9
ec_funded: 1
file:
- access_level: open_access
checksum: 685f91bd077a951ba067d42cce75409e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:36Z
date_updated: 2020-07-14T12:45:03Z
file_id: '4697'
file_name: IST-2016-594-v1+1_HTCylinder_GD_Revision.pdf
file_size: 330135
relation: main_file
file_date_updated: 2020-07-14T12:45:03Z
has_accepted_license: '1'
intvolume: ' 9411'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 99 - 110
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Springer
publist_id: '5576'
pubrep_id: '594'
quality_controlled: '1'
related_material:
record:
- id: '1113'
relation: later_version
status: public
- id: '1164'
relation: later_version
status: public
scopus_import: 1
status: public
title: Hanani-Tutte for radial planarity
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 9411
year: '2015'
...
---
_id: '1590'
abstract:
- lang: eng
text: 'The straight skeleton of a polygon is the geometric graph obtained by tracing
the vertices during a mitered offsetting process. It is known that the straight
skeleton of a simple polygon is a tree, and one can naturally derive directions
on the edges of the tree from the propagation of the shrinking process. In this
paper, we ask the reverse question: Given a tree with directed edges, can it be
the straight skeleton of a polygon? And if so, can we find a suitable simple polygon?
We answer these questions for all directed trees where the order of edges around
each node is fixed.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Oswin
full_name: Aichholzer, Oswin
last_name: Aichholzer
- first_name: Therese
full_name: Biedl, Therese
last_name: Biedl
- first_name: Thomas
full_name: Hackl, Thomas
last_name: Hackl
- first_name: Martin
full_name: Held, Martin
last_name: Held
- first_name: Stefan
full_name: Huber, Stefan
id: 4700A070-F248-11E8-B48F-1D18A9856A87
last_name: Huber
orcid: 0000-0002-8871-5814
- first_name: Peter
full_name: Palfrader, Peter
last_name: Palfrader
- first_name: Birgit
full_name: Vogtenhuber, Birgit
last_name: Vogtenhuber
citation:
ama: 'Aichholzer O, Biedl T, Hackl T, et al. Representing directed trees as straight
skeletons. In: Graph Drawing and Network Visualization. Vol 9411. Springer
Nature; 2015:335-347. doi:10.1007/978-3-319-27261-0_28'
apa: 'Aichholzer, O., Biedl, T., Hackl, T., Held, M., Huber, S., Palfrader, P.,
& Vogtenhuber, B. (2015). Representing directed trees as straight skeletons.
In Graph Drawing and Network Visualization (Vol. 9411, pp. 335–347). Los
Angeles, CA, United States: Springer Nature. https://doi.org/10.1007/978-3-319-27261-0_28'
chicago: Aichholzer, Oswin, Therese Biedl, Thomas Hackl, Martin Held, Stefan Huber,
Peter Palfrader, and Birgit Vogtenhuber. “Representing Directed Trees as Straight
Skeletons.” In Graph Drawing and Network Visualization, 9411:335–47. Springer
Nature, 2015. https://doi.org/10.1007/978-3-319-27261-0_28.
ieee: O. Aichholzer et al., “Representing directed trees as straight skeletons,”
in Graph Drawing and Network Visualization, vol. 9411, Springer Nature,
2015, pp. 335–347.
ista: 'Aichholzer O, Biedl T, Hackl T, Held M, Huber S, Palfrader P, Vogtenhuber
B. 2015.Representing directed trees as straight skeletons. In: Graph Drawing and
Network Visualization. LNCS, vol. 9411, 335–347.'
mla: Aichholzer, Oswin, et al. “Representing Directed Trees as Straight Skeletons.”
Graph Drawing and Network Visualization, vol. 9411, Springer Nature, 2015,
pp. 335–47, doi:10.1007/978-3-319-27261-0_28.
short: O. Aichholzer, T. Biedl, T. Hackl, M. Held, S. Huber, P. Palfrader, B. Vogtenhuber,
in:, Graph Drawing and Network Visualization, Springer Nature, 2015, pp. 335–347.
conference:
end_date: 2015-09-26
location: Los Angeles, CA, United States
name: 'GD: International Symposium on Graph Drawing'
start_date: 2015-09-24
date_created: 2018-12-11T11:52:54Z
date_published: 2015-11-27T00:00:00Z
date_updated: 2022-01-28T09:10:37Z
day: '27'
department:
- _id: HeEd
doi: 10.1007/978-3-319-27261-0_28
intvolume: ' 9411'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1508.01076
month: '11'
oa: 1
oa_version: Preprint
page: 335 - 347
publication: Graph Drawing and Network Visualization
publication_identifier:
eisbn:
- 978-3-319-27261-0
isbn:
- 978-3-319-27260-3
publication_status: published
publisher: Springer Nature
publist_id: '5581'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Representing directed trees as straight skeletons
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9411
year: '2015'
...
---
_id: '1596'
abstract:
- lang: eng
text: Let C={C1,...,Cn} denote a collection of translates of a regular convex k-gon
in the plane with the stacking order. The collection C forms a visibility clique
if for everyi < j the intersection Ci and (Ci ∩ Cj)\⋃i<l<jCl =∅.elements
that are stacked between them, i.e., We show that if C forms a visibility clique
its size is bounded from above by O(k4) thereby improving the upper bound of 22k
from the aforementioned paper. We also obtain an upper bound of 22(k/2)+2 on the
size of a visibility clique for homothetes of a convex (not necessarily regular)
k-gon.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Radoslav
full_name: Fulek, Radoslav
id: 39F3FFE4-F248-11E8-B48F-1D18A9856A87
last_name: Fulek
orcid: 0000-0001-8485-1774
- first_name: Radoš
full_name: Radoičić, Radoš
last_name: Radoičić
citation:
ama: 'Fulek R, Radoičić R. Vertical visibility among parallel polygons in three
dimensions. In: Graph Drawing and Network Visualization. Vol 9411. Springer
Nature; 2015:373-379. doi:10.1007/978-3-319-27261-0_31'
apa: 'Fulek, R., & Radoičić, R. (2015). Vertical visibility among parallel polygons
in three dimensions. In Graph Drawing and Network Visualization (Vol. 9411,
pp. 373–379). Los Angeles, CA, United States: Springer Nature. https://doi.org/10.1007/978-3-319-27261-0_31'
chicago: Fulek, Radoslav, and Radoš Radoičić. “Vertical Visibility among Parallel
Polygons in Three Dimensions.” In Graph Drawing and Network Visualization,
9411:373–79. Springer Nature, 2015. https://doi.org/10.1007/978-3-319-27261-0_31.
ieee: R. Fulek and R. Radoičić, “Vertical visibility among parallel polygons in
three dimensions,” in Graph Drawing and Network Visualization, vol. 9411,
Springer Nature, 2015, pp. 373–379.
ista: 'Fulek R, Radoičić R. 2015.Vertical visibility among parallel polygons in
three dimensions. In: Graph Drawing and Network Visualization. LNCS, vol. 9411,
373–379.'
mla: Fulek, Radoslav, and Radoš Radoičić. “Vertical Visibility among Parallel Polygons
in Three Dimensions.” Graph Drawing and Network Visualization, vol. 9411,
Springer Nature, 2015, pp. 373–79, doi:10.1007/978-3-319-27261-0_31.
short: R. Fulek, R. Radoičić, in:, Graph Drawing and Network Visualization, Springer
Nature, 2015, pp. 373–379.
conference:
end_date: 2015-09-26
location: Los Angeles, CA, United States
name: 'GD: Graph Drawing and Network Visualization'
start_date: 2015-09-24
date_created: 2018-12-11T11:52:56Z
date_published: 2015-11-27T00:00:00Z
date_updated: 2022-01-28T09:20:50Z
day: '27'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1007/978-3-319-27261-0_31
ec_funded: 1
file:
- access_level: open_access
checksum: eec04f86c5921d04f025d5791db9b965
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:06Z
date_updated: 2020-07-14T12:45:04Z
file_id: '5258'
file_name: IST-2016-595-v1+1_VerticalVisibilityGDRevision.pdf
file_size: 312992
relation: main_file
file_date_updated: 2020-07-14T12:45:04Z
has_accepted_license: '1'
intvolume: ' 9411'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 373 - 379
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Graph Drawing and Network Visualization
publication_identifier:
isbn:
- 978-3-319-27260-3
publication_status: published
publisher: Springer Nature
publist_id: '5575'
pubrep_id: '595'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Vertical visibility among parallel polygons in three dimensions
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9411
year: '2015'
...
---
_id: '1601'
abstract:
- lang: eng
text: We propose a flexible exchange format for ω-automata, as typically used in
formal verification, and implement support for it in a range of established tools.
Our aim is to simplify the interaction of tools, helping the research community
to build upon other people’s work. A key feature of the format is the use of very
generic acceptance conditions, specified by Boolean combinations of acceptance
primitives, rather than being limited to common cases such as Büchi, Streett,
or Rabin. Such flexibility in the choice of acceptance conditions can be exploited
in applications, for example in probabilistic model checking, and furthermore
encourages the development of acceptance-agnostic tools for automata manipulations.
The format allows acceptance conditions that are either state-based or transition-based,
and also supports alternating automata.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Tomáš
full_name: Babiak, Tomáš
last_name: Babiak
- first_name: František
full_name: Blahoudek, František
last_name: Blahoudek
- first_name: Alexandre
full_name: Duret Lutz, Alexandre
last_name: Duret Lutz
- first_name: Joachim
full_name: Klein, Joachim
last_name: Klein
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Daniel
full_name: Mueller, Daniel
last_name: Mueller
- first_name: David
full_name: Parker, David
last_name: Parker
- first_name: Jan
full_name: Strejček, Jan
last_name: Strejček
citation:
ama: 'Babiak T, Blahoudek F, Duret Lutz A, et al. The Hanoi omega-automata format.
In: Vol 9206. Springer; 2015:479-486. doi:10.1007/978-3-319-21690-4_31'
apa: 'Babiak, T., Blahoudek, F., Duret Lutz, A., Klein, J., Kretinsky, J., Mueller,
D., … Strejček, J. (2015). The Hanoi omega-automata format (Vol. 9206, pp. 479–486).
Presented at the CAV: Computer Aided Verification, San Francisco, CA, United States:
Springer. https://doi.org/10.1007/978-3-319-21690-4_31'
chicago: Babiak, Tomáš, František Blahoudek, Alexandre Duret Lutz, Joachim Klein,
Jan Kretinsky, Daniel Mueller, David Parker, and Jan Strejček. “The Hanoi Omega-Automata
Format,” 9206:479–86. Springer, 2015. https://doi.org/10.1007/978-3-319-21690-4_31.
ieee: 'T. Babiak et al., “The Hanoi omega-automata format,” presented at
the CAV: Computer Aided Verification, San Francisco, CA, United States, 2015,
vol. 9206, pp. 479–486.'
ista: 'Babiak T, Blahoudek F, Duret Lutz A, Klein J, Kretinsky J, Mueller D, Parker
D, Strejček J. 2015. The Hanoi omega-automata format. CAV: Computer Aided Verification,
LNCS, vol. 9206, 479–486.'
mla: Babiak, Tomáš, et al. The Hanoi Omega-Automata Format. Vol. 9206, Springer,
2015, pp. 479–86, doi:10.1007/978-3-319-21690-4_31.
short: T. Babiak, F. Blahoudek, A. Duret Lutz, J. Klein, J. Kretinsky, D. Mueller,
D. Parker, J. Strejček, in:, Springer, 2015, pp. 479–486.
conference:
end_date: 2015-07-24
location: San Francisco, CA, United States
name: 'CAV: Computer Aided Verification'
start_date: 2015-07-18
date_created: 2018-12-11T11:52:57Z
date_published: 2015-07-16T00:00:00Z
date_updated: 2021-01-12T06:51:54Z
day: '16'
ddc:
- '000'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/978-3-319-21690-4_31
ec_funded: 1
file:
- access_level: open_access
checksum: 5885236fa88a439baba9ac6f3e801e93
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T08:38:12Z
date_updated: 2020-07-14T12:45:04Z
file_id: '7850'
file_name: 2015_CAV_Babiak.pdf
file_size: 1651779
relation: main_file
file_date_updated: 2020-07-14T12:45:04Z
has_accepted_license: '1'
intvolume: ' 9206'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 479 - 486
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '5566'
quality_controlled: '1'
scopus_import: 1
status: public
title: The Hanoi omega-automata format
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9206
year: '2015'
...
---
_id: '1605'
abstract:
- lang: eng
text: Multiaffine hybrid automata (MHA) represent a powerful formalism to model
complex dynamical systems. This formalism is particularly suited for the representation
of biological systems which often exhibit highly non-linear behavior. In this
paper, we consider the problem of parameter identification for MHA. We present
an abstraction of MHA based on linear hybrid automata, which can be analyzed by
the SpaceEx model checker. This abstraction enables a precise handling of time-dependent
properties. We demonstrate the potential of our approach on a model of a genetic
regulatory network and a myocyte model.
acknowledgement: This work was partly supported by the European Research Council (ERC)
under grant 267989 (QUAREM), by the Austrian Science Fund (FWF) under grants S11402-N23,
S11405-N23 and S11412-N23 (RiSE/SHiNE) and Z211-N23 (Wittgenstein Award), and by
the German Research Foundation (DFG) as part of the Transregional Collaborative
Research Center “Automatic Verification and Analysis of Complex Systems” (SFB/TR
14 AVACS, http://www.avacs.org/).
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sergiy
full_name: Bogomolov, Sergiy
id: 369D9A44-F248-11E8-B48F-1D18A9856A87
last_name: Bogomolov
orcid: 0000-0002-0686-0365
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
- first_name: Ezio
full_name: Bartocci, Ezio
last_name: Bartocci
- first_name: Grégory
full_name: Batt, Grégory
last_name: Batt
- first_name: Hui
full_name: Kong, Hui
id: 3BDE25AA-F248-11E8-B48F-1D18A9856A87
last_name: Kong
orcid: 0000-0002-3066-6941
- first_name: Radu
full_name: Grosu, Radu
last_name: Grosu
citation:
ama: 'Bogomolov S, Schilling C, Bartocci E, Batt G, Kong H, Grosu R. Abstraction-based
parameter synthesis for multiaffine systems. In: Vol 9434. Springer; 2015:19-35.
doi:10.1007/978-3-319-26287-1_2'
apa: 'Bogomolov, S., Schilling, C., Bartocci, E., Batt, G., Kong, H., & Grosu,
R. (2015). Abstraction-based parameter synthesis for multiaffine systems (Vol.
9434, pp. 19–35). Presented at the HVC: Haifa Verification Conference, Haifa,
Israel: Springer. https://doi.org/10.1007/978-3-319-26287-1_2'
chicago: Bogomolov, Sergiy, Christian Schilling, Ezio Bartocci, Grégory Batt, Hui
Kong, and Radu Grosu. “Abstraction-Based Parameter Synthesis for Multiaffine Systems,”
9434:19–35. Springer, 2015. https://doi.org/10.1007/978-3-319-26287-1_2.
ieee: 'S. Bogomolov, C. Schilling, E. Bartocci, G. Batt, H. Kong, and R. Grosu,
“Abstraction-based parameter synthesis for multiaffine systems,” presented at
the HVC: Haifa Verification Conference, Haifa, Israel, 2015, vol. 9434, pp. 19–35.'
ista: 'Bogomolov S, Schilling C, Bartocci E, Batt G, Kong H, Grosu R. 2015. Abstraction-based
parameter synthesis for multiaffine systems. HVC: Haifa Verification Conference,
LNCS, vol. 9434, 19–35.'
mla: Bogomolov, Sergiy, et al. Abstraction-Based Parameter Synthesis for Multiaffine
Systems. Vol. 9434, Springer, 2015, pp. 19–35, doi:10.1007/978-3-319-26287-1_2.
short: S. Bogomolov, C. Schilling, E. Bartocci, G. Batt, H. Kong, R. Grosu, in:,
Springer, 2015, pp. 19–35.
conference:
end_date: 2015-11-19
location: Haifa, Israel
name: 'HVC: Haifa Verification Conference'
start_date: 2015-11-17
date_created: 2018-12-11T11:52:59Z
date_published: 2015-11-28T00:00:00Z
date_updated: 2021-01-12T06:51:56Z
day: '28'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-319-26287-1_2
ec_funded: 1
file:
- access_level: open_access
checksum: 3aab260f3f34641d622030ba22645b3e
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T08:43:19Z
date_updated: 2020-07-14T12:45:05Z
file_id: '7851'
file_name: 2015_LNCS_Bogomolov.pdf
file_size: 1053207
relation: main_file
file_date_updated: 2020-07-14T12:45:05Z
has_accepted_license: '1'
intvolume: ' 9434'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 19 - 35
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '5561'
quality_controlled: '1'
scopus_import: 1
status: public
title: Abstraction-based parameter synthesis for multiaffine systems
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9434
year: '2015'
...
---
_id: '1609'
abstract:
- lang: eng
text: The synthesis problem asks for the automatic construction of a system from
its specification. In the traditional setting, the system is “constructed from
scratch” rather than composed from reusable components. However, this is rare
in practice, and almost every non-trivial software system relies heavily on the
use of libraries of reusable components. Recently, Lustig and Vardi introduced
dataflow and controlflow synthesis from libraries of reusable components. They
proved that dataflow synthesis is undecidable, while controlflow synthesis is
decidable. The problem of controlflow synthesis from libraries of probabilistic
components was considered by Nain, Lustig and Vardi, and was shown to be decidable
for qualitative analysis (that asks that the specification be satisfied with probability
1). Our main contribution for controlflow synthesis from probabilistic components
is to establish better complexity bounds for the qualitative analysis problem,
and to show that the more general quantitative problem is undecidable. For the
qualitative analysis, we show that the problem (i) is EXPTIME-complete when the
specification is given as a deterministic parity word automaton, improving the
previously known 2EXPTIME upper bound; and (ii) belongs to UP ∩ coUP and is parity-games
hard, when the specification is given directly as a parity condition on the components,
improving the previously known EXPTIME upper bound.
acknowledgement: 'This research was supported by Austrian Science Fund (FWF) Grant
No P23499- N23, FWF NFN Grant No S11407-N23 (SHiNE), ERC Start grant (279307: Graph
Games), EU FP7 Project Cassting, NSF grants CNS 1049862 and CCF-1139011, by NSF
Expeditions in Computing project “ExCAPE: Expeditions in Computer Augmented Program
Engineering”, by BSF grant 9800096, and by gift from Intel.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Moshe
full_name: Vardi, Moshe
last_name: Vardi
citation:
ama: 'Chatterjee K, Doyen L, Vardi M. The complexity of synthesis from probabilistic
components. In: 42nd International Colloquium. Vol 9135. Springer Nature;
2015:108-120. doi:10.1007/978-3-662-47666-6_9'
apa: 'Chatterjee, K., Doyen, L., & Vardi, M. (2015). The complexity of synthesis
from probabilistic components. In 42nd International Colloquium (Vol. 9135,
pp. 108–120). Kyoto, Japan: Springer Nature. https://doi.org/10.1007/978-3-662-47666-6_9'
chicago: Chatterjee, Krishnendu, Laurent Doyen, and Moshe Vardi. “The Complexity
of Synthesis from Probabilistic Components.” In 42nd International Colloquium,
9135:108–20. Springer Nature, 2015. https://doi.org/10.1007/978-3-662-47666-6_9.
ieee: K. Chatterjee, L. Doyen, and M. Vardi, “The complexity of synthesis from probabilistic
components,” in 42nd International Colloquium, Kyoto, Japan, 2015, vol.
9135, pp. 108–120.
ista: 'Chatterjee K, Doyen L, Vardi M. 2015. The complexity of synthesis from probabilistic
components. 42nd International Colloquium. ICALP: Automata, Languages and Programming,
LNCS, vol. 9135, 108–120.'
mla: Chatterjee, Krishnendu, et al. “The Complexity of Synthesis from Probabilistic
Components.” 42nd International Colloquium, vol. 9135, Springer Nature,
2015, pp. 108–20, doi:10.1007/978-3-662-47666-6_9.
short: K. Chatterjee, L. Doyen, M. Vardi, in:, 42nd International Colloquium, Springer
Nature, 2015, pp. 108–120.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'ICALP: Automata, Languages and Programming'
start_date: 2015-07-06
date_created: 2018-12-11T11:53:00Z
date_published: 2015-06-20T00:00:00Z
date_updated: 2022-02-01T15:04:44Z
day: '20'
department:
- _id: KrCh
doi: 10.1007/978-3-662-47666-6_9
ec_funded: 1
intvolume: ' 9135'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1502.04844
month: '06'
oa: 1
oa_version: Preprint
page: 108 - 120
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: 42nd International Colloquium
publication_identifier:
isbn:
- 978-3-662-47665-9
publication_status: published
publisher: Springer Nature
publist_id: '5557'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The complexity of synthesis from probabilistic components
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9135
year: '2015'
...
---
_id: '1615'
abstract:
- lang: eng
text: Loss-of-function mutations in the synaptic adhesion protein Neuroligin-4 are
among the most common genetic abnormalities associated with autism spectrum disorders,
but little is known about the function of Neuroligin-4 and the consequences of
its loss. We assessed synaptic and network characteristics in Neuroligin-4 knockout
mice, focusing on the hippocampus as a model brain region with a critical role
in cognition and memory, and found that Neuroligin-4 deletion causes subtle defects
of the protein composition and function of GABAergic synapses in the hippocampal
CA3 region. Interestingly, these subtle synaptic changes are accompanied by pronounced
perturbations of γ-oscillatory network activity, which has been implicated in
cognitive function and is altered in multiple psychiatric and neurodevelopmental
disorders. Our data provide important insights into the mechanisms by which Neuroligin-4-dependent
GABAergic synapses may contribute to autism phenotypes and indicate new strategies
for therapeutic approaches.
acknowledgement: This work was supported by the Max Planck Society (N.B. and H.E.),
the European Commission (EU-AIMS FP7-115300, N.B. and H.E.; Marie Curie IRG, D.K.-B.),
the German Research Foundation (CNMPB, N.B., H.E., and F.V.), the Alexander von
Humboldt-Foundation (D.K.-B.), and the Austrian Fond zur Förderung der Wissenschaftlichen
Forschung (P 24909-B24, P.J.). M.H. was a student of the doctoral program Molecular
Physiology of the Brain. Dr. J.-M. Fritschy generously provided the GABAARγ2 antibody.
We thank F. Benseler, I. Thanhäuser, D. Schwerdtfeger, A. Ronnenberg, and D. Winkler
for valuable advice and excellent technical support. We are grateful to the staff
at the animal facility of the Max Planck Institute of Experimental Medicine for
mouse husbandry.
author:
- first_name: Matthieu
full_name: Hammer, Matthieu
last_name: Hammer
- first_name: Dilja
full_name: Krueger Burg, Dilja
last_name: Krueger Burg
- first_name: Liam
full_name: Tuffy, Liam
last_name: Tuffy
- first_name: Benjamin
full_name: Cooper, Benjamin
last_name: Cooper
- first_name: Holger
full_name: Taschenberger, Holger
last_name: Taschenberger
- first_name: Sarit
full_name: Goswami, Sarit
id: 3A578F32-F248-11E8-B48F-1D18A9856A87
last_name: Goswami
- first_name: Hannelore
full_name: Ehrenreich, Hannelore
last_name: Ehrenreich
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Frederique
full_name: Varoqueaux, Frederique
last_name: Varoqueaux
- first_name: Jeong
full_name: Rhee, Jeong
last_name: Rhee
- first_name: Nils
full_name: Brose, Nils
last_name: Brose
citation:
ama: Hammer M, Krueger Burg D, Tuffy L, et al. Perturbed hippocampal synaptic inhibition
and γ-oscillations in a neuroligin-4 knockout mouse model of autism. Cell Reports.
2015;13(3):516-523. doi:10.1016/j.celrep.2015.09.011
apa: Hammer, M., Krueger Burg, D., Tuffy, L., Cooper, B., Taschenberger, H., Goswami,
S., … Brose, N. (2015). Perturbed hippocampal synaptic inhibition and γ-oscillations
in a neuroligin-4 knockout mouse model of autism. Cell Reports. Cell Press.
https://doi.org/10.1016/j.celrep.2015.09.011
chicago: Hammer, Matthieu, Dilja Krueger Burg, Liam Tuffy, Benjamin Cooper, Holger
Taschenberger, Sarit Goswami, Hannelore Ehrenreich, et al. “Perturbed Hippocampal
Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model
of Autism.” Cell Reports. Cell Press, 2015. https://doi.org/10.1016/j.celrep.2015.09.011.
ieee: M. Hammer et al., “Perturbed hippocampal synaptic inhibition and γ-oscillations
in a neuroligin-4 knockout mouse model of autism,” Cell Reports, vol. 13,
no. 3. Cell Press, pp. 516–523, 2015.
ista: Hammer M, Krueger Burg D, Tuffy L, Cooper B, Taschenberger H, Goswami S, Ehrenreich
H, Jonas PM, Varoqueaux F, Rhee J, Brose N. 2015. Perturbed hippocampal synaptic
inhibition and γ-oscillations in a neuroligin-4 knockout mouse model of autism.
Cell Reports. 13(3), 516–523.
mla: Hammer, Matthieu, et al. “Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations
in a Neuroligin-4 Knockout Mouse Model of Autism.” Cell Reports, vol. 13,
no. 3, Cell Press, 2015, pp. 516–23, doi:10.1016/j.celrep.2015.09.011.
short: M. Hammer, D. Krueger Burg, L. Tuffy, B. Cooper, H. Taschenberger, S. Goswami,
H. Ehrenreich, P.M. Jonas, F. Varoqueaux, J. Rhee, N. Brose, Cell Reports 13 (2015)
516–523.
date_created: 2018-12-11T11:53:02Z
date_published: 2015-10-20T00:00:00Z
date_updated: 2021-01-12T06:52:01Z
day: '20'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.celrep.2015.09.011
file:
- access_level: open_access
checksum: 44d30fbb543774b076b4938bd36af9d7
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:23Z
date_updated: 2020-07-14T12:45:07Z
file_id: '5005'
file_name: IST-2016-470-v1+1_1-s2.0-S2211124715010220-main.pdf
file_size: 2314406
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 13'
issue: '3'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 516 - 523
publication: Cell Reports
publication_status: published
publisher: Cell Press
publist_id: '5551'
pubrep_id: '470'
quality_controlled: '1'
scopus_import: 1
status: public
title: Perturbed hippocampal synaptic inhibition and γ-oscillations in a neuroligin-4
knockout mouse model of autism
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2015'
...
---
_id: '1614'
abstract:
- lang: eng
text: 'GABAergic perisoma-inhibiting fast-spiking interneurons (PIIs) effectively
control the activity of large neuron populations by their wide axonal arborizations.
It is generally assumed that the output of one PII to its target cells is strong
and rapid. Here, we show that, unexpectedly, both strength and time course of
PII-mediated perisomatic inhibition change with distance between synaptically
connected partners in the rodent hippocampus. Synaptic signals become weaker due
to lower contact numbers and decay more slowly with distance, very likely resulting
from changes in GABAA receptor subunit composition. When distance-dependent synaptic
inhibition is introduced to a rhythmically active neuronal network model, randomly
driven principal cell assemblies are strongly synchronized by the PIIs, leading
to higher precision in principal cell spike times than in a network with uniform
synaptic inhibition. '
author:
- first_name: Michael
full_name: Strüber, Michael
last_name: Strüber
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Marlene
full_name: Bartos, Marlene
last_name: Bartos
citation:
ama: Strüber M, Jonas PM, Bartos M. Strength and duration of perisomatic GABAergic
inhibition depend on distance between synaptically connected cells. PNAS.
2015;112(4):1220-1225. doi:10.1073/pnas.1412996112
apa: Strüber, M., Jonas, P. M., & Bartos, M. (2015). Strength and duration of
perisomatic GABAergic inhibition depend on distance between synaptically connected
cells. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1412996112
chicago: Strüber, Michael, Peter M Jonas, and Marlene Bartos. “Strength and Duration
of Perisomatic GABAergic Inhibition Depend on Distance between Synaptically Connected
Cells.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1412996112.
ieee: M. Strüber, P. M. Jonas, and M. Bartos, “Strength and duration of perisomatic
GABAergic inhibition depend on distance between synaptically connected cells,”
PNAS, vol. 112, no. 4. National Academy of Sciences, pp. 1220–1225, 2015.
ista: Strüber M, Jonas PM, Bartos M. 2015. Strength and duration of perisomatic
GABAergic inhibition depend on distance between synaptically connected cells.
PNAS. 112(4), 1220–1225.
mla: Strüber, Michael, et al. “Strength and Duration of Perisomatic GABAergic Inhibition
Depend on Distance between Synaptically Connected Cells.” PNAS, vol. 112,
no. 4, National Academy of Sciences, 2015, pp. 1220–25, doi:10.1073/pnas.1412996112.
short: M. Strüber, P.M. Jonas, M. Bartos, PNAS 112 (2015) 1220–1225.
date_created: 2018-12-11T11:53:02Z
date_published: 2015-01-27T00:00:00Z
date_updated: 2021-01-12T06:52:01Z
day: '27'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1073/pnas.1412996112
ec_funded: 1
external_id:
pmid:
- '25583495'
file:
- access_level: open_access
checksum: 6703309a1f58493cf5a704211fb6ebed
content_type: application/pdf
creator: dernst
date_created: 2019-01-17T07:52:40Z
date_updated: 2020-07-14T12:45:07Z
file_id: '5838'
file_name: 2015_PNAS_Strueber.pdf
file_size: 1280860
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 112'
issue: '4'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 1220 - 1225
pmid: 1
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5552'
quality_controlled: '1'
scopus_import: 1
status: public
title: Strength and duration of perisomatic GABAergic inhibition depend on distance
between synaptically connected cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1611'
abstract:
- lang: eng
text: Biosensors for signaling molecules allow the study of physiological processes
by bringing together the fields of protein engineering, fluorescence imaging,
and cell biology. Construction of genetically encoded biosensors generally relies
on the availability of a binding "core" that is both specific and stable,
which can then be combined with fluorescent molecules to create a sensor. However,
binding proteins with the desired properties are often not available in nature
and substantial improvement to sensors can be required, particularly with regard
to their durability. Ancestral protein reconstruction is a powerful protein-engineering
tool able to generate highly stable and functional proteins. In this work, we
sought to establish the utility of ancestral protein reconstruction to biosensor
development, beginning with the construction of an l-arginine biosensor. l-arginine,
as the immediate precursor to nitric oxide, is an important molecule in many physiological
contexts including brain function. Using a combination of ancestral reconstruction
and circular permutation, we constructed a Förster resonance energy transfer (FRET)
biosensor for l-arginine (cpFLIPR). cpFLIPR displays high sensitivity and specificity,
with a Kd of ∼14 μM and a maximal dynamic range of 35%. Importantly, cpFLIPR was
highly robust, enabling accurate l-arginine measurement at physiological temperatures.
We established that cpFLIPR is compatible with two-photon excitation fluorescence
microscopy and report l-arginine concentrations in brain tissue.
author:
- first_name: Jason
full_name: Whitfield, Jason
last_name: Whitfield
- first_name: William
full_name: Zhang, William
last_name: Zhang
- first_name: Michel
full_name: Herde, Michel
last_name: Herde
- first_name: Ben
full_name: Clifton, Ben
last_name: Clifton
- first_name: Johanna
full_name: Radziejewski, Johanna
last_name: Radziejewski
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Christian
full_name: Henneberger, Christian
last_name: Henneberger
- first_name: Colin
full_name: Jackson, Colin
last_name: Jackson
citation:
ama: Whitfield J, Zhang W, Herde M, et al. Construction of a robust and sensitive
arginine biosensor through ancestral protein reconstruction. Protein Science.
2015;24(9):1412-1422. doi:10.1002/pro.2721
apa: Whitfield, J., Zhang, W., Herde, M., Clifton, B., Radziejewski, J., Janovjak,
H. L., … Jackson, C. (2015). Construction of a robust and sensitive arginine biosensor
through ancestral protein reconstruction. Protein Science. Wiley. https://doi.org/10.1002/pro.2721
chicago: Whitfield, Jason, William Zhang, Michel Herde, Ben Clifton, Johanna Radziejewski,
Harald L Janovjak, Christian Henneberger, and Colin Jackson. “Construction of
a Robust and Sensitive Arginine Biosensor through Ancestral Protein Reconstruction.”
Protein Science. Wiley, 2015. https://doi.org/10.1002/pro.2721.
ieee: J. Whitfield et al., “Construction of a robust and sensitive arginine
biosensor through ancestral protein reconstruction,” Protein Science, vol.
24, no. 9. Wiley, pp. 1412–1422, 2015.
ista: Whitfield J, Zhang W, Herde M, Clifton B, Radziejewski J, Janovjak HL, Henneberger
C, Jackson C. 2015. Construction of a robust and sensitive arginine biosensor
through ancestral protein reconstruction. Protein Science. 24(9), 1412–1422.
mla: Whitfield, Jason, et al. “Construction of a Robust and Sensitive Arginine Biosensor
through Ancestral Protein Reconstruction.” Protein Science, vol. 24, no.
9, Wiley, 2015, pp. 1412–22, doi:10.1002/pro.2721.
short: J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak,
C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
date_created: 2018-12-11T11:53:01Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:52:00Z
day: '01'
department:
- _id: HaJa
doi: 10.1002/pro.2721
external_id:
pmid:
- '26061224'
intvolume: ' 24'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570536/
month: '09'
oa: 1
oa_version: Submitted Version
page: 1412 - 1422
pmid: 1
project:
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
grant_number: RGY0084/2012
name: In situ real-time imaging of neurotransmitter signaling using designer optical
sensors (HFSP Young Investigator)
publication: Protein Science
publication_status: published
publisher: Wiley
publist_id: '5555'
quality_controlled: '1'
scopus_import: 1
status: public
title: Construction of a robust and sensitive arginine biosensor through ancestral
protein reconstruction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2015'
...
---
_id: '1624'
abstract:
- lang: eng
text: Population structure can facilitate evolution of cooperation. In a structured
population, cooperators can form clusters which resist exploitation by defectors.
Recently, it was observed that a shift update rule is an extremely strong amplifier
of cooperation in a one dimensional spatial model. For the shift update rule,
an individual is chosen for reproduction proportional to fecundity; the offspring
is placed next to the parent; a random individual dies. Subsequently, the population
is rearranged (shifted) until all individual cells are again evenly spaced out.
For large population size and a one dimensional population structure, the shift
update rule favors cooperation for any benefit-to-cost ratio greater than one.
But every attempt to generalize shift updating to higher dimensions while maintaining
its strong effect has failed. The reason is that in two dimensions the clusters
are fragmented by the movements caused by rearranging the cells. Here we introduce
the natural phenomenon of a repulsive force between cells of different types.
After a birth and death event, the cells are being rearranged minimizing the overall
energy expenditure. If the repulsive force is sufficiently high, shift becomes
a strong promoter of cooperation in two dimensions.
acknowledgement: 'The research was supported by the Austrian Science Fund (FWF) Grant
No P23499-N23, FWF NFN Grant No S11407-N23 (RiSE/SHiNE), ERC Start grant (279307:
Graph Games), and Microsoft Faculty Fellows award. Support from the John Templeton
foundation is gratefully acknowledged.'
article_number: '17147'
author:
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Ben
full_name: Adlam, Ben
last_name: Adlam
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Pavlogiannis A, Chatterjee K, Adlam B, Nowak M. Cellular cooperation with shift
updating and repulsion. Scientific Reports. 2015;5. doi:10.1038/srep17147
apa: Pavlogiannis, A., Chatterjee, K., Adlam, B., & Nowak, M. (2015). Cellular
cooperation with shift updating and repulsion. Scientific Reports. Nature
Publishing Group. https://doi.org/10.1038/srep17147
chicago: Pavlogiannis, Andreas, Krishnendu Chatterjee, Ben Adlam, and Martin Nowak.
“Cellular Cooperation with Shift Updating and Repulsion.” Scientific Reports.
Nature Publishing Group, 2015. https://doi.org/10.1038/srep17147.
ieee: A. Pavlogiannis, K. Chatterjee, B. Adlam, and M. Nowak, “Cellular cooperation
with shift updating and repulsion,” Scientific Reports, vol. 5. Nature
Publishing Group, 2015.
ista: Pavlogiannis A, Chatterjee K, Adlam B, Nowak M. 2015. Cellular cooperation
with shift updating and repulsion. Scientific Reports. 5, 17147.
mla: Pavlogiannis, Andreas, et al. “Cellular Cooperation with Shift Updating and
Repulsion.” Scientific Reports, vol. 5, 17147, Nature Publishing Group,
2015, doi:10.1038/srep17147.
short: A. Pavlogiannis, K. Chatterjee, B. Adlam, M. Nowak, Scientific Reports 5
(2015).
date_created: 2018-12-11T11:53:06Z
date_published: 2015-11-25T00:00:00Z
date_updated: 2021-01-12T06:52:05Z
day: '25'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1038/srep17147
ec_funded: 1
file:
- access_level: open_access
checksum: 38e06d8310d2087cae5f6d4d4bfe082b
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:29Z
date_updated: 2020-07-14T12:45:07Z
file_id: '4947'
file_name: IST-2016-466-v1+1_srep17147.pdf
file_size: 1021931
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '5536'
pubrep_id: '466'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cellular cooperation with shift updating and repulsion
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2015'
...
---
_id: '1623'
abstract:
- lang: eng
text: "Background\r\nPhotosynthetic cyanobacteria are attractive for a range of
biotechnological applications including biofuel production. However, due to slow
growth, screening of mutant libraries using microtiter plates is not feasible.\r\nResults\r\nWe
present a method for high-throughput, single-cell analysis and sorting of genetically
engineered l-lactate-producing strains of Synechocystis sp. PCC6803. A microfluidic
device is used to encapsulate single cells in picoliter droplets, assay the droplets
for l-lactate production, and sort strains with high productivity. We demonstrate
the separation of low- and high-producing reference strains, as well as enrichment
of a more productive l-lactate-synthesizing population after UV-induced mutagenesis.
The droplet platform also revealed population heterogeneity in photosynthetic
growth and lactate production, as well as the presence of metabolically stalled
cells.\r\nConclusions\r\nThe workflow will facilitate metabolic engineering and
directed evolution studies and will be useful in studies of cyanobacteria biochemistry
and physiology.\r\n"
article_number: '193'
author:
- first_name: Petter
full_name: Hammar, Petter
last_name: Hammar
- first_name: Andreas
full_name: Angermayr, Andreas
id: 4677C796-F248-11E8-B48F-1D18A9856A87
last_name: Angermayr
orcid: 0000-0001-8619-2223
- first_name: Staffan
full_name: Sjostrom, Staffan
last_name: Sjostrom
- first_name: Josefin
full_name: Van Der Meer, Josefin
last_name: Van Der Meer
- first_name: Klaas
full_name: Hellingwerf, Klaas
last_name: Hellingwerf
- first_name: Elton
full_name: Hudson, Elton
last_name: Hudson
- first_name: Hakaan
full_name: Joensson, Hakaan
last_name: Joensson
citation:
ama: Hammar P, Angermayr A, Sjostrom S, et al. Single-cell screening of photosynthetic
growth and lactate production by cyanobacteria. Biotechnology for Biofuels.
2015;8(1). doi:10.1186/s13068-015-0380-2
apa: Hammar, P., Angermayr, A., Sjostrom, S., Van Der Meer, J., Hellingwerf, K.,
Hudson, E., & Joensson, H. (2015). Single-cell screening of photosynthetic
growth and lactate production by cyanobacteria. Biotechnology for Biofuels.
BioMed Central. https://doi.org/10.1186/s13068-015-0380-2
chicago: Hammar, Petter, Andreas Angermayr, Staffan Sjostrom, Josefin Van Der Meer,
Klaas Hellingwerf, Elton Hudson, and Hakaan Joensson. “Single-Cell Screening of
Photosynthetic Growth and Lactate Production by Cyanobacteria.” Biotechnology
for Biofuels. BioMed Central, 2015. https://doi.org/10.1186/s13068-015-0380-2.
ieee: P. Hammar et al., “Single-cell screening of photosynthetic growth and
lactate production by cyanobacteria,” Biotechnology for Biofuels, vol.
8, no. 1. BioMed Central, 2015.
ista: Hammar P, Angermayr A, Sjostrom S, Van Der Meer J, Hellingwerf K, Hudson E,
Joensson H. 2015. Single-cell screening of photosynthetic growth and lactate production
by cyanobacteria. Biotechnology for Biofuels. 8(1), 193.
mla: Hammar, Petter, et al. “Single-Cell Screening of Photosynthetic Growth and
Lactate Production by Cyanobacteria.” Biotechnology for Biofuels, vol.
8, no. 1, 193, BioMed Central, 2015, doi:10.1186/s13068-015-0380-2.
short: P. Hammar, A. Angermayr, S. Sjostrom, J. Van Der Meer, K. Hellingwerf, E.
Hudson, H. Joensson, Biotechnology for Biofuels 8 (2015).
date_created: 2018-12-11T11:53:05Z
date_published: 2015-11-25T00:00:00Z
date_updated: 2021-01-12T06:52:04Z
day: '25'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.1186/s13068-015-0380-2
file:
- access_level: open_access
checksum: 172b0b6f4eb2e5c22b7cec1d57dc0107
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:11Z
date_updated: 2020-07-14T12:45:07Z
file_id: '4796'
file_name: IST-2016-467-v1+1_s13068-015-0380-2.pdf
file_size: 2914089
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Biotechnology for Biofuels
publication_status: published
publisher: BioMed Central
publist_id: '5537'
pubrep_id: '467'
quality_controlled: '1'
scopus_import: 1
status: public
title: Single-cell screening of photosynthetic growth and lactate production by cyanobacteria
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1628'
abstract:
- lang: eng
text: We propose a method for fabricating deformable objects with spatially varying
elasticity using 3D printing. Using a single, relatively stiff printer material,
our method designs an assembly of smallscale microstructures that have the effect
of a softer material at the object scale, with properties depending on the microstructure
used in each part of the object. We build on work in the area of metamaterials,
using numerical optimization to design tiled microstructures with desired properties,
but with the key difference that our method designs families of related structures
that can be interpolated to smoothly vary the material properties over a wide
range. To create an object with spatially varying elastic properties, we tile
the object's interior with microstructures drawn from these families, generating
a different microstructure for each cell using an efficient algorithm to select
compatible structures for neighboring cells. We show results computed for both
2D and 3D objects, validating several 2D and 3D printed structures using standard
material tests as well as demonstrating various example applications.
article_number: '136'
article_processing_charge: No
author:
- first_name: Christian
full_name: Schumacher, Christian
last_name: Schumacher
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Jan
full_name: Rys, Jan
last_name: Rys
- first_name: Steve
full_name: Marschner, Steve
last_name: Marschner
- first_name: Chiara
full_name: Daraio, Chiara
last_name: Daraio
- first_name: Markus
full_name: Gross, Markus
last_name: Gross
citation:
ama: 'Schumacher C, Bickel B, Rys J, Marschner S, Daraio C, Gross M. Microstructures
to control elasticity in 3D printing. In: Vol 34. ACM; 2015. doi:10.1145/2766926'
apa: 'Schumacher, C., Bickel, B., Rys, J., Marschner, S., Daraio, C., & Gross,
M. (2015). Microstructures to control elasticity in 3D printing (Vol. 34). Presented
at the SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques,
Los Angeles, CA, USA: ACM. https://doi.org/10.1145/2766926'
chicago: Schumacher, Christian, Bernd Bickel, Jan Rys, Steve Marschner, Chiara Daraio,
and Markus Gross. “Microstructures to Control Elasticity in 3D Printing,” Vol.
34. ACM, 2015. https://doi.org/10.1145/2766926.
ieee: 'C. Schumacher, B. Bickel, J. Rys, S. Marschner, C. Daraio, and M. Gross,
“Microstructures to control elasticity in 3D printing,” presented at the SIGGRAPH:
Special Interest Group on Computer Graphics and Interactive Techniques, Los Angeles,
CA, USA, 2015, vol. 34, no. 4.'
ista: 'Schumacher C, Bickel B, Rys J, Marschner S, Daraio C, Gross M. 2015. Microstructures
to control elasticity in 3D printing. SIGGRAPH: Special Interest Group on Computer
Graphics and Interactive Techniques vol. 34, 136.'
mla: Schumacher, Christian, et al. Microstructures to Control Elasticity in 3D
Printing. Vol. 34, no. 4, 136, ACM, 2015, doi:10.1145/2766926.
short: C. Schumacher, B. Bickel, J. Rys, S. Marschner, C. Daraio, M. Gross, in:,
ACM, 2015.
conference:
end_date: 2015-08-13
location: Los Angeles, CA, USA
name: 'SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques'
start_date: 2015-08-09
date_created: 2018-12-11T11:53:07Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:52:06Z
day: '01'
department:
- _id: BeBi
doi: 10.1145/2766926
intvolume: ' 34'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1145/2766926
month: '08'
oa: 1
oa_version: Published Version
publication_status: published
publisher: ACM
publist_id: '5529'
quality_controlled: '1'
scopus_import: 1
status: public
title: Microstructures to control elasticity in 3D printing
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1634'
abstract:
- lang: eng
text: Simulating the delightful dynamics of soap films, bubbles, and foams has traditionally
required the use of a fully three-dimensional many-phase Navier-Stokes solver,
even though their visual appearance is completely dominated by the thin liquid
surface. We depart from earlier work on soap bubbles and foams by noting that
their dynamics are naturally described by a Lagrangian vortex sheet model in which
circulation is the primary variable. This leads us to derive a novel circulation-preserving
surface-only discretization of foam dynamics driven by surface tension on a non-manifold
triangle mesh. We represent the surface using a mesh-based multimaterial surface
tracker which supports complex bubble topology changes, and evolve the surface
according to the ambient air flow induced by a scalar circulation field stored
on the mesh. Surface tension forces give rise to a simple update rule for circulation,
even at non-manifold Plateau borders, based on a discrete measure of signed scalar
mean curvature. We further incorporate vertex constraints to enable the interaction
of soap films with wires. The result is a method that is at once simple, robust,
and efficient, yet able to capture an array of soap films behaviors including
foam rearrangement, catenoid collapse, blowing bubbles, and double bubbles being
pulled apart.
article_number: '149'
author:
- first_name: Fang
full_name: Da, Fang
last_name: Da
- first_name: Christopher
full_name: Batty, Christopher
last_name: Batty
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
- first_name: Eitan
full_name: Grinspun, Eitan
last_name: Grinspun
citation:
ama: 'Da F, Batty C, Wojtan C, Grinspun E. Double bubbles sans toil and trouble:
discrete circulation-preserving vortex sheets for soap films and foams. In: Vol
34. ACM; 2015. doi:10.1145/2767003'
apa: 'Da, F., Batty, C., Wojtan, C., & Grinspun, E. (2015). Double bubbles sans
toil and trouble: discrete circulation-preserving vortex sheets for soap films
and foams (Vol. 34). Presented at the SIGGRAPH: Special Interest Group on Computer
Graphics and Interactive Techniques, Los Angeles, CA, United States: ACM. https://doi.org/10.1145/2767003'
chicago: 'Da, Fang, Christopher Batty, Chris Wojtan, and Eitan Grinspun. “Double
Bubbles sans Toil and Trouble: Discrete Circulation-Preserving Vortex Sheets for
Soap Films and Foams,” Vol. 34. ACM, 2015. https://doi.org/10.1145/2767003.'
ieee: 'F. Da, C. Batty, C. Wojtan, and E. Grinspun, “Double bubbles sans toil and
trouble: discrete circulation-preserving vortex sheets for soap films and foams,”
presented at the SIGGRAPH: Special Interest Group on Computer Graphics and Interactive
Techniques, Los Angeles, CA, United States, 2015, vol. 34, no. 4.'
ista: 'Da F, Batty C, Wojtan C, Grinspun E. 2015. Double bubbles sans toil and trouble:
discrete circulation-preserving vortex sheets for soap films and foams. SIGGRAPH:
Special Interest Group on Computer Graphics and Interactive Techniques vol. 34,
149.'
mla: 'Da, Fang, et al. Double Bubbles sans Toil and Trouble: Discrete Circulation-Preserving
Vortex Sheets for Soap Films and Foams. Vol. 34, no. 4, 149, ACM, 2015, doi:10.1145/2767003.'
short: F. Da, C. Batty, C. Wojtan, E. Grinspun, in:, ACM, 2015.
conference:
end_date: 2015-08-13
location: Los Angeles, CA, United States
name: 'SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques'
start_date: 2015-08-09
date_created: 2018-12-11T11:53:09Z
date_published: 2015-07-27T00:00:00Z
date_updated: 2023-02-23T10:07:42Z
day: '27'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2767003
ec_funded: 1
file:
- access_level: open_access
checksum: 57b07d78d2d612a8052744b37d4a71fa
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:14Z
date_updated: 2020-07-14T12:45:07Z
file_id: '4867'
file_name: IST-2016-608-v1+1_doublebubbles.pdf
file_size: 8973215
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '638176'
name: Efficient Simulation of Natural Phenomena at Extremely Large Scales
publication_status: published
publisher: ACM
publist_id: '5521'
pubrep_id: '608'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Double bubbles sans toil and trouble: discrete circulation-preserving vortex
sheets for soap films and foams'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...