---
_id: '17170'
abstract:
- lang: eng
text: "In this article we extend and strengthen the seminal work by Niyogi, Smale,
and Weinberger on the learning of the homotopy type from a sample of an underlying
space. In their work, Niyogi, Smale, and Weinberger studied samples of C² manifolds
with positive reach embedded in ℝ^d. We extend their results in the following
ways: - As the ambient space we consider both ℝ^d and Riemannian manifolds with
lower bounded sectional curvature. - In both types of ambient spaces, we study
sets of positive reach - a significantly more general setting than C² manifolds
- as well as general manifolds of positive reach. - The sample P of a set (or
a manifold) \U0001D4AE of positive reach may be noisy. We work with two one-sided
Hausdorff distances - ε and δ - between P and \U0001D4AE. We provide tight bounds
in terms of ε and δ, that guarantee that there exists a parameter r such that
the union of balls of radius r centred at the sample P deformation-retracts to
\U0001D4AE. We exhibit their tightness by an explicit construction. We carefully
distinguish the roles of δ and ε. This is not only essential to achieve tight
bounds, but also sensible in practical situations, since it allows one to adapt
the bound according to sample density and the amount of noise present in the sample
separately."
acknowledgement: "This research has been supported by the European Research Council
(ERC), grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF),
grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian
Science Fund (FWF), grant No. I 02979-N35.\r\nWintraecken, Mathijs: Supported by
the European Union’s Horizon 2020 research and innovation programme under the Marie
Skłodowska-Curie grant agreement No. 754411, the Austrian science fund (FWF) grant
No. M-3073, and the welcome package from IDEX of the Université Côte d'Azur."
alternative_title:
- LIPIcs
article_processing_charge: No
arxiv: 1
author:
- first_name: Dominique
full_name: Attali, Dominique
last_name: Attali
- first_name: Hana
full_name: Kourimska, Hana
id: D9B8E14C-3C26-11EA-98F5-1F833DDC885E
last_name: Kourimska
orcid: 0000-0001-7841-0091
- first_name: Christopher D
full_name: Fillmore, Christopher D
id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
last_name: Fillmore
- first_name: Ishika
full_name: Ghosh, Ishika
id: ee449b28-344d-11ef-a6d5-9ca430e9e9ff
last_name: Ghosh
- first_name: André
full_name: Lieutier, André
last_name: Lieutier
- first_name: Elizabeth R
full_name: Stephenson, Elizabeth R
id: 2D04F932-F248-11E8-B48F-1D18A9856A87
last_name: Stephenson
orcid: 0000-0002-6862-208X
- first_name: Mathijs
full_name: Wintraecken, Mathijs
id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
last_name: Wintraecken
orcid: 0000-0002-7472-2220
citation:
ama: 'Attali D, Kourimska H, Fillmore CD, et al. Tight bounds for the learning of
homotopy à la Niyogi, Smale, and Weinberger for subsets of euclidean spaces and
of Riemannian manifolds. In: 40th International Symposium on Computational
Geometry. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024:11:1-11:19.
doi:10.4230/LIPIcs.SoCG.2024.11'
apa: 'Attali, D., Kourimska, H., Fillmore, C. D., Ghosh, I., Lieutier, A., Stephenson,
E. R., & Wintraecken, M. (2024). Tight bounds for the learning of homotopy
à la Niyogi, Smale, and Weinberger for subsets of euclidean spaces and of Riemannian
manifolds. In 40th International Symposium on Computational Geometry (Vol.
293, p. 11:1-11:19). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
https://doi.org/10.4230/LIPIcs.SoCG.2024.11'
chicago: Attali, Dominique, Hana Kourimska, Christopher D Fillmore, Ishika Ghosh,
André Lieutier, Elizabeth R Stephenson, and Mathijs Wintraecken. “Tight Bounds
for the Learning of Homotopy à La Niyogi, Smale, and Weinberger for Subsets of
Euclidean Spaces and of Riemannian Manifolds.” In 40th International Symposium
on Computational Geometry, 293:11:1-11:19. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2024. https://doi.org/10.4230/LIPIcs.SoCG.2024.11.
ieee: D. Attali et al., “Tight bounds for the learning of homotopy à la Niyogi,
Smale, and Weinberger for subsets of euclidean spaces and of Riemannian manifolds,”
in 40th International Symposium on Computational Geometry, Athens, Greece,
2024, vol. 293, p. 11:1-11:19.
ista: 'Attali D, Kourimska H, Fillmore CD, Ghosh I, Lieutier A, Stephenson ER, Wintraecken
M. 2024. Tight bounds for the learning of homotopy à la Niyogi, Smale, and Weinberger
for subsets of euclidean spaces and of Riemannian manifolds. 40th International
Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry,
LIPIcs, vol. 293, 11:1-11:19.'
mla: Attali, Dominique, et al. “Tight Bounds for the Learning of Homotopy à La Niyogi,
Smale, and Weinberger for Subsets of Euclidean Spaces and of Riemannian Manifolds.”
40th International Symposium on Computational Geometry, vol. 293, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2024, p. 11:1-11:19, doi:10.4230/LIPIcs.SoCG.2024.11.
short: D. Attali, H. Kourimska, C.D. Fillmore, I. Ghosh, A. Lieutier, E.R. Stephenson,
M. Wintraecken, in:, 40th International Symposium on Computational Geometry, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2024, p. 11:1-11:19.
conference:
end_date: 2024-06-14
location: Athens, Greece
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2024-06-11
date_created: 2024-06-25T11:45:58Z
date_published: 2024-06-06T00:00:00Z
date_updated: 2025-04-15T07:16:57Z
day: '06'
ddc:
- '516'
department:
- _id: GradSch
- _id: HeEd
doi: 10.4230/LIPIcs.SoCG.2024.11
ec_funded: 1
external_id:
arxiv:
- '2206.10485'
file:
- access_level: open_access
checksum: 6a2ddc8b51aa58f197a8b294750f1f8d
content_type: application/pdf
creator: cfillmor
date_created: 2024-06-25T11:47:26Z
date_updated: 2024-06-25T11:47:26Z
file_id: '17171'
file_name: LIPIcs.SoCG.2024.11.pdf
file_size: 20886142
relation: main_file
success: 1
file_date_updated: 2024-06-25T11:47:26Z
fulldoi: https://doi.org/10.4230/LIPIcs.SoCG.2024.11
has_accepted_license: '1'
intvolume: ' 293'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '06'
oa: 1
oa_version: Published Version
page: 11:1-11:19
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
grant_number: M03073
name: Learning and triangulating manifolds via collapses
publication: 40th International Symposium on Computational Geometry
publication_identifier:
eissn:
- 1868-8969
isbn:
- '9783959773164'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tight bounds for the learning of homotopy à la Niyogi, Smale, and Weinberger
for subsets of euclidean spaces and of Riemannian manifolds
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 293
year: '2024'
...
---
APC_amount: 804 EUR
OA_place: publisher
OA_type: gold
_id: '17187'
abstract:
- lang: eng
text: "The generation of diverse cell types during development is fundamental to
brain\r\nfunctions. We outline a protocol to quantitatively assess the clonal
output of individual neural progenitors using mosaic analysis with double markers
(MADM) in\r\nmice. We first describe steps to acquire and reconstruct adult MADM
clones in\r\nthe superior colliculus. Then we detail analysis pipelines to determine
clonal\r\ncomposition and architecture. This protocol enables the buildup of quantitative\r\nframeworks
of lineage progression with precise spatial resolution in the brain.\r\nFor complete
details on the use and execution of this protocol, please refer to\r\nCheung et
al.1"
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: We thank A. Heger for mouse breeding support. This work was supported
by the Scientific Service Units of IST Austria through resources provided by the
Imaging & Optics and Preclinical facilities. G.C. received funding from the European
Commission (IST plus postdoctoral fellowship); S.H. was funded by ISTA institutional
funds and the Austrian Science Fund Special Research Programmes (FWF SFB-F78 Neuro
Stem Modulation).
article_number: '103157'
article_processing_charge: Yes
article_type: original
author:
- first_name: Giselle T
full_name: Cheung, Giselle T
id: 471195F6-F248-11E8-B48F-1D18A9856A87
last_name: Cheung
orcid: 0000-0001-8457-2572
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Cheung GT, Streicher C, Hippenmeyer S. Protocol for quantitative reconstruction
of cell lineage using mosaic analysis with double markers in mice. STAR Protocols.
2024;5(3). doi:10.1016/j.xpro.2024.103157
apa: Cheung, G. T., Streicher, C., & Hippenmeyer, S. (2024). Protocol for quantitative
reconstruction of cell lineage using mosaic analysis with double markers in mice.
STAR Protocols. Elsevier. https://doi.org/10.1016/j.xpro.2024.103157
chicago: Cheung, Giselle T, Carmen Streicher, and Simon Hippenmeyer. “Protocol for
Quantitative Reconstruction of Cell Lineage Using Mosaic Analysis with Double
Markers in Mice.” STAR Protocols. Elsevier, 2024. https://doi.org/10.1016/j.xpro.2024.103157.
ieee: G. T. Cheung, C. Streicher, and S. Hippenmeyer, “Protocol for quantitative
reconstruction of cell lineage using mosaic analysis with double markers in mice,”
STAR Protocols, vol. 5, no. 3. Elsevier, 2024.
ista: Cheung GT, Streicher C, Hippenmeyer S. 2024. Protocol for quantitative reconstruction
of cell lineage using mosaic analysis with double markers in mice. STAR Protocols.
5(3), 103157.
mla: Cheung, Giselle T., et al. “Protocol for Quantitative Reconstruction of Cell
Lineage Using Mosaic Analysis with Double Markers in Mice.” STAR Protocols,
vol. 5, no. 3, 103157, Elsevier, 2024, doi:10.1016/j.xpro.2024.103157.
short: G.T. Cheung, C. Streicher, S. Hippenmeyer, STAR Protocols 5 (2024).
corr_author: '1'
date_created: 2024-06-30T22:01:04Z
date_published: 2024-09-20T00:00:00Z
date_updated: 2025-12-30T10:54:11Z
day: '20'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.xpro.2024.103157
ec_funded: 1
external_id:
pmid:
- '38935508'
file:
- access_level: open_access
checksum: d8a8cdba82a394e731aa699ace1ae433
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T12:12:40Z
date_updated: 2025-01-09T12:12:40Z
file_id: '18809'
file_name: 2024_STARProtoc_Cheung.pdf
file_size: 5186071
relation: main_file
success: 1
file_date_updated: 2025-01-09T12:12:40Z
fulldoi: https://doi.org/10.1016/j.xpro.2024.103157
has_accepted_license: '1'
intvolume: ' 5'
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
grant_number: F7805
name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
Mechanisms of Neural Stem Cell Lineage Progression
publication: STAR Protocols
publication_identifier:
eissn:
- 2666-1667
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Protocol for quantitative reconstruction of cell lineage using mosaic analysis
with double markers in mice
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '17188'
abstract:
- lang: eng
text: "In a delegation problem, a principal P with commitment power tries to pick
one out of \U0001D45B options.\r\nEach option is drawn independently from a known
distribution. Instead of inspecting the options\r\nherself, P delegates the information
acquisition to a rational and self-interested agent A. After\r\ninspection, A
proposes one of the options, and P can accept or reject.\r\nDelegation is a classic
setting in economic information design with many prominent applications,\r\nbut
the computational problems are only poorly understood. In this paper, we study
a natural\r\nonline variant of delegation, in which the agent searches through
the options in an online fashion.\r\nFor each option, he has to irrevocably decide
if he wants to propose the current option or discard\r\nit, before seeing information
on the next option(s). How can we design algorithms for P that\r\napproximate
the utility of her best option in hindsight?\r\nWe show that in general P can
obtain a Θ(1∕\U0001D45B)-approximation and extend this result to ratios\r\nof
Θ(\U0001D458∕\U0001D45B) in case (1) A has a lookahead of \U0001D458 rounds, or
(2) A can propose up to \U0001D458 different\r\noptions. We provide fine-grained
bounds independent of \U0001D45B based on three parameters. If the ratio\r\nof
maximum and minimum utility for A is bounded by a factor \U0001D6FC, we obtain
an Ω(loglog \U0001D6FC∕ log \U0001D6FC)-\r\napproximation algorithm, and we show
that this is best possible. Additionally, if P cannot\r\ndistinguish options with
the same value for herself, we show that ratios polynomial in 1∕\U0001D6FC cannot\r\nbe
avoided. If there are at most \U0001D6FD different utility values for A, we show
a Θ(1∕\U0001D6FD)-approximation.\r\nIf the utilities of P and A for each option
are related by a factor \U0001D6FE, we obtain an Ω(1∕ log \U0001D6FE)-\r\napproximation,
where \U0001D442(log log \U0001D6FE∕ log \U0001D6FE) is best possible."
acknowledgement: Hahn gratefully acknowledges the support of GIF grant I-1419-118.4/2017.
Hoefer gratefully acknowledges the support of GIF grant I-1419-118.4/2017, DFG Research
Unit ADYN (project number 411362735), and DFG grant Ho 3831/9-1 (project number
514505843).
article_number: '104171'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Pirmin
full_name: Braun, Pirmin
last_name: Braun
- first_name: Niklas
full_name: Hahn, Niklas
id: 0a01c7b2-b823-11ed-9928-cc3f874f9ffd
last_name: Hahn
- first_name: Martin
full_name: Hoefer, Martin
last_name: Hoefer
- first_name: Conrad
full_name: Schecker, Conrad
last_name: Schecker
citation:
ama: Braun P, Hahn N, Hoefer M, Schecker C. Delegated online search. Artificial
Intelligence. 2024;334. doi:10.1016/j.artint.2024.104171
apa: Braun, P., Hahn, N., Hoefer, M., & Schecker, C. (2024). Delegated online
search. Artificial Intelligence. Elsevier. https://doi.org/10.1016/j.artint.2024.104171
chicago: Braun, Pirmin, Niklas Hahn, Martin Hoefer, and Conrad Schecker. “Delegated
Online Search.” Artificial Intelligence. Elsevier, 2024. https://doi.org/10.1016/j.artint.2024.104171.
ieee: P. Braun, N. Hahn, M. Hoefer, and C. Schecker, “Delegated online search,”
Artificial Intelligence, vol. 334. Elsevier, 2024.
ista: Braun P, Hahn N, Hoefer M, Schecker C. 2024. Delegated online search. Artificial
Intelligence. 334, 104171.
mla: Braun, Pirmin, et al. “Delegated Online Search.” Artificial Intelligence,
vol. 334, 104171, Elsevier, 2024, doi:10.1016/j.artint.2024.104171.
short: P. Braun, N. Hahn, M. Hoefer, C. Schecker, Artificial Intelligence 334 (2024).
corr_author: '1'
date_created: 2024-06-30T22:01:05Z
date_published: 2024-09-01T00:00:00Z
date_updated: 2025-09-08T08:00:42Z
day: '01'
ddc:
- '000'
department:
- _id: MoHe
doi: 10.1016/j.artint.2024.104171
external_id:
arxiv:
- '2203.01084'
isi:
- '001260448100001'
file:
- access_level: open_access
checksum: f02a56bc7ea88f41fcc68968e4ceddf3
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T10:45:24Z
date_updated: 2025-01-09T10:45:24Z
file_id: '18806'
file_name: 2024_ArtificialIntelligence_Braun.pdf
file_size: 772226
relation: main_file
success: 1
file_date_updated: 2025-01-09T10:45:24Z
fulldoi: https://doi.org/10.1016/j.artint.2024.104171
has_accepted_license: '1'
intvolume: ' 334'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Artificial Intelligence
publication_identifier:
issn:
- 0004-3702
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Delegated online search
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 334
year: '2024'
...
---
_id: '17190'
abstract:
- lang: eng
text: "For a locally finite set, \U0001D434⊆ℝ\U0001D451\r\n, the \U0001D458\r\nth
Brillouin zone of \U0001D44E∈\U0001D434\r\n is the region of points \U0001D465∈ℝ\U0001D451\r\n
for which ‖\U0001D465−\U0001D44E‖\r\n is the \U0001D458\r\nth smallest among the
Euclidean distances between \U0001D465\r\n and the points in \U0001D434\r\n. If
\U0001D434\r\n is a lattice, the \U0001D458\r\nth Brillouin zones of the points
in \U0001D434\r\n are translates of each other, and together they tile space.
Depending on the value of \U0001D458\r\n, they express medium- or long-range order
in the set. We study fundamental geometric and combinatorial properties of Brillouin
zones, focusing on the integer lattice and its perturbations. Our results include
the stability of a Brillouin zone under perturbations, a linear upper bound on
the number of chambers in a zone for lattices in ℝ2\r\n, and the convergence of
the maximum volume of a chamber to zero for the integer lattice."
acknowledgement: The second author is partially supported by the Alexander von Humboldt
Foundation. The sixth author is supported by the European Union's Horizon 2020 research
and innovation programme under Marie Sklodowska-Curie grant agreement 754411, and
by Austrian Science Fund(FWF) grant M-3073. All other authors are supported by European
Research Council (ERC) grant 788183, by the Wittgenstein Prize, by Austrian Science
Fund (FWF) grant Z 342-N31, and by the DFG Collaborative Research Center TRR 109,
Austrian Science Fund (FWF) grant I 02979-N35.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Alexey
full_name: Garber, Alexey
last_name: Garber
- first_name: Mohadese
full_name: Ghafaris, Mohadese
last_name: Ghafaris
- first_name: Teresa
full_name: Heiss, Teresa
id: 4879BB4E-F248-11E8-B48F-1D18A9856A87
last_name: Heiss
orcid: 0000-0002-1780-2689
- first_name: Morteza
full_name: Saghafiant, Morteza
last_name: Saghafiant
- first_name: Mathijs
full_name: Wintraecken, Mathijs
id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
last_name: Wintraecken
orcid: 0000-0002-7472-2220
citation:
ama: Edelsbrunner H, Garber A, Ghafaris M, Heiss T, Saghafiant M, Wintraecken M.
Brillouin zones of integer lattices and their perturbations. SIAM Journal on
Discrete Mathematics. 2024;38(2):1784-1807. doi:10.1137/22M1489071
apa: Edelsbrunner, H., Garber, A., Ghafaris, M., Heiss, T., Saghafiant, M., &
Wintraecken, M. (2024). Brillouin zones of integer lattices and their perturbations.
SIAM Journal on Discrete Mathematics. Society for Industrial and Applied
Mathematics. https://doi.org/10.1137/22M1489071
chicago: Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafaris, Teresa Heiss,
Morteza Saghafiant, and Mathijs Wintraecken. “Brillouin Zones of Integer Lattices
and Their Perturbations.” SIAM Journal on Discrete Mathematics. Society
for Industrial and Applied Mathematics, 2024. https://doi.org/10.1137/22M1489071.
ieee: H. Edelsbrunner, A. Garber, M. Ghafaris, T. Heiss, M. Saghafiant, and M. Wintraecken,
“Brillouin zones of integer lattices and their perturbations,” SIAM Journal
on Discrete Mathematics, vol. 38, no. 2. Society for Industrial and Applied
Mathematics, pp. 1784–1807, 2024.
ista: Edelsbrunner H, Garber A, Ghafaris M, Heiss T, Saghafiant M, Wintraecken M.
2024. Brillouin zones of integer lattices and their perturbations. SIAM Journal
on Discrete Mathematics. 38(2), 1784–1807.
mla: Edelsbrunner, Herbert, et al. “Brillouin Zones of Integer Lattices and Their
Perturbations.” SIAM Journal on Discrete Mathematics, vol. 38, no. 2, Society
for Industrial and Applied Mathematics, 2024, pp. 1784–807, doi:10.1137/22M1489071.
short: H. Edelsbrunner, A. Garber, M. Ghafaris, T. Heiss, M. Saghafiant, M. Wintraecken,
SIAM Journal on Discrete Mathematics 38 (2024) 1784–1807.
corr_author: '1'
date_created: 2024-06-30T22:01:05Z
date_published: 2024-06-07T00:00:00Z
date_updated: 2025-09-08T08:06:04Z
day: '07'
department:
- _id: HeEd
doi: 10.1137/22M1489071
ec_funded: 1
external_id:
arxiv:
- '2204.01077'
isi:
- '001292728600001'
fulldoi: https://doi.org/10.1137/22M1489071
intvolume: ' 38'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2204.01077
month: '06'
oa: 1
oa_version: Preprint
page: 1784-1807
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
grant_number: M03073
name: Learning and triangulating manifolds via collapses
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: Mathematics, Computer Science
publication: SIAM Journal on Discrete Mathematics
publication_identifier:
issn:
- 0895-4801
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Brillouin zones of integer lattices and their perturbations
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 38
year: '2024'
...
---
_id: '17196'
abstract:
- lang: eng
text: This .zip File contains the data for the figures presented in the main text
and supplementary material of "A gate tunable transmon qubit in planar Ge" by
O.Sagi et al. The measurements were done using Qcodes. The description of the
files and the instructions on opening the data can be found in the Readme. An
additional Jupyter Notebook is attached that walks through the data analysis.
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: 'This research was supported by the Scientific Service Units of ISTA
through resources provided by the MIBA Machine Shop and the Nanofabrication facility. '
article_processing_charge: No
author:
- first_name: Oliver
full_name: Sagi, Oliver
id: 71616374-A8E9-11E9-A7CA-09ECE5697425
last_name: Sagi
citation:
ama: Sagi O. A gate-tunable transmon in planar Ge. 2024. doi:10.15479/AT:ISTA:17196
apa: Sagi, O. (2024). A gate-tunable transmon in planar Ge. Institute of Science
and Technology Austria. https://doi.org/10.15479/AT:ISTA:17196
chicago: Sagi, Oliver. “A Gate-Tunable Transmon in Planar Ge.” Institute of Science
and Technology Austria, 2024. https://doi.org/10.15479/AT:ISTA:17196.
ieee: O. Sagi, “A gate-tunable transmon in planar Ge.” Institute of Science and
Technology Austria, 2024.
ista: Sagi O. 2024. A gate-tunable transmon in planar Ge, Institute of Science and
Technology Austria, 10.15479/AT:ISTA:17196.
mla: Sagi, Oliver. A Gate-Tunable Transmon in Planar Ge. Institute of Science
and Technology Austria, 2024, doi:10.15479/AT:ISTA:17196.
short: O. Sagi, (2024).
contributor:
- contributor_type: project_member
first_name: Alessandro
id: 1F2B21A2-F6E7-11E9-9B82-F7DBE5697425
last_name: Crippa
orcid: 0000-0002-2968-611X
- contributor_type: project_member
first_name: Marco
id: C0BB2FAC-D767-11E9-B658-BC13E6697425
last_name: Valentini
- contributor_type: project_member
first_name: Marian
id: 396A1950-F248-11E8-B48F-1D18A9856A87
last_name: Janik
- contributor_type: project_member
first_name: Levon
id: 7aa1f788-b527-11ee-aa9e-e6111a79e0c7
last_name: Baghumyan
- contributor_type: project_member
first_name: Giorgio
id: 298cf6f3-1ff6-11ee-9fa6-d94cfa0b3352
last_name: Fabris
- contributor_type: project_member
first_name: Lucky
id: 84b9700b-15b2-11ec-abd3-831089e67615
last_name: Kapoor
- contributor_type: project_member
first_name: Farid
id: 2AED110C-F248-11E8-B48F-1D18A9856A87
last_name: Hassani
orcid: 0000-0001-6937-5773
- contributor_type: project_member
first_name: Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- contributor_type: project_member
first_name: Stefano
last_name: Calcaterra
- contributor_type: project_member
first_name: Daniel
last_name: Chrastina
- contributor_type: project_member
first_name: Giovanni
last_name: Isella
- contributor_type: supervisor
first_name: Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
corr_author: '1'
date_created: 2024-07-04T10:14:34Z
date_published: 2024-07-04T00:00:00Z
date_updated: 2026-04-16T12:20:39Z
day: '04'
ddc:
- '530'
department:
- _id: GradSch
- _id: GeKa
- _id: JoFi
doi: 10.15479/AT:ISTA:17196
file:
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checksum: a9f640a0b72a92171353f3ea14406f0b
content_type: application/octet-stream
creator: osagi
date_created: 2024-07-04T10:01:51Z
date_updated: 2024-07-04T10:01:51Z
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content_type: application/vnd.openxmlformats-officedocument.presentationml.presentation
creator: osagi
date_created: 2024-07-04T10:01:50Z
date_updated: 2024-07-04T10:01:50Z
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file_name: OlSa_Readme.pptx
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creator: osagi
date_created: 2024-07-04T10:11:16Z
date_updated: 2024-07-04T10:11:16Z
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creator: osagi
date_created: 2024-07-04T10:11:40Z
date_updated: 2024-07-04T10:11:40Z
file_id: '17200'
file_name: Gatemon_RT_5nm_1.zip
file_size: 465618029
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content_type: application/x-zip-compressed
creator: osagi
date_created: 2024-07-04T10:11:35Z
date_updated: 2024-07-04T10:11:35Z
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file_date_updated: 2024-07-04T10:11:40Z
fulldoi: https://doi.org/10.15479/AT:ISTA:17196
has_accepted_license: '1'
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: c0977eea-5a5b-11eb-8a69-a862db0cf4d1
grant_number: I05060
name: High impedance circuit quantum electrodynamics with hole spins
- _id: 262116AA-B435-11E9-9278-68D0E5697425
name: Hybrid Semiconductor - Superconductor Quantum Devices
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
grant_number: P36507
name: Merging spin and superconducting qubits in planar Ge
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '17202'
relation: used_in_publication
status: public
status: public
title: A gate-tunable transmon in planar Ge
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2024'
...
---
APC_amount: 6828 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18444'
abstract:
- lang: eng
text: Animals rely on compensatory actions to maintain stability and navigate their
environment efficiently. These actions depend on global visual motion cues known
as optic-flow. While the optomotor response has been the traditional focus for
studying optic-flow compensation in insects, its simplicity has been insufficient
to determine the role of the intricate optic-flow processing network involved
in visual course control. Here, we reveal a series of course control behaviours
in Drosophila and link them to specific neural circuits. We show that bilateral
electrical coupling of optic-flow-sensitive neurons in the fly’s lobula plate
are required for a proper course control. This electrical interaction works alongside
chemical synapses within the HS-H2 network to control the dynamics and direction
of turning behaviours. Our findings reveal how insects use bilateral motion cues
for navigation, assigning a new functional significance to the HS-H2 network and
suggesting a previously unknown role for gap junctions in non-linear operations.
acknowledged_ssus:
- _id: Bio
- _id: M-Shop
- _id: LifeSc
acknowledgement: We thank Georg Ammer and Alexander Borst for sharing anti-ShakB serum
antibodies. We thank Nélia Varela and Eugenia Chiappe for the w1118;+;10XUAS-IVS-eGFPKir2.1/TM6B
fly line, Augustin Hrvoje for the shakB[2] line, as well as Jesse Isaacman-Beck
and Thomas R Clandinin for the gift of y1,w*;20XUAS-IVS-PhiC31;+ fly line. We also
thank Armel Nicolas and Tomas Masson for the proteomic analysis, Ece Sönmez for
help with fly crosses and dissections for protein analysis, and Lisa Hofer for assistance
with the reconstruction experiments. We would also like to thank Laura Burnett for
drawing scientific illustrations used in the figures. We are particularly grateful
to members of the Siekhaus, the Kondrashov, and the Chiappe group for providing
material support and technical advice. We are grateful to Daria Siekhaus, Eugenia
Chiappe, Alexander Borst, Ben deBivort, and all the members of the Joesch laboratory
for valuable discussions and comments on the manuscript. Stocks from the Bloomington
Drosophila Stock Center (NIH P40OD018537) and the Vienna Drosophila Resource Center
were used in this study. The Scientific Service Units of ISTA supported the project
through resources provided by the Imaging and Optics Facility, MIBA Machine Shop,
and the Lab Support Facility, as well as Vienna Drosophila Research Centre. This
work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)
as part of the SPP 2205 – 429960716 (M.J.).
article_number: '8830'
article_processing_charge: Yes
article_type: original
author:
- first_name: Victoria
full_name: Pokusaeva, Victoria
id: 3184041C-F248-11E8-B48F-1D18A9856A87
last_name: Pokusaeva
orcid: 0000-0001-7660-444X
- first_name: Roshan K
full_name: Satapathy, Roshan K
id: 46046B7A-F248-11E8-B48F-1D18A9856A87
last_name: Satapathy
orcid: 0009-0006-2974-5075
- first_name: Olga
full_name: Symonova, Olga
id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
last_name: Symonova
orcid: 0000-0003-2012-9947
- first_name: Maximilian A
full_name: Jösch, Maximilian A
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
citation:
ama: Pokusaeva V, Satapathy RK, Symonova O, Jösch MA. Bilateral interactions of
optic-flow sensitive neurons coordinate course control in flies. Nature Communications.
2024;15. doi:10.1038/s41467-024-53173-w
apa: Pokusaeva, V., Satapathy, R. K., Symonova, O., & Jösch, M. A. (2024). Bilateral
interactions of optic-flow sensitive neurons coordinate course control in flies.
Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-024-53173-w
chicago: Pokusaeva, Victoria, Roshan K Satapathy, Olga Symonova, and Maximilian
A Jösch. “Bilateral Interactions of Optic-Flow Sensitive Neurons Coordinate Course
Control in Flies.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53173-w.
ieee: V. Pokusaeva, R. K. Satapathy, O. Symonova, and M. A. Jösch, “Bilateral interactions
of optic-flow sensitive neurons coordinate course control in flies,” Nature
Communications, vol. 15. Springer Nature, 2024.
ista: Pokusaeva V, Satapathy RK, Symonova O, Jösch MA. 2024. Bilateral interactions
of optic-flow sensitive neurons coordinate course control in flies. Nature Communications.
15, 8830.
mla: Pokusaeva, Victoria, et al. “Bilateral Interactions of Optic-Flow Sensitive
Neurons Coordinate Course Control in Flies.” Nature Communications, vol.
15, 8830, Springer Nature, 2024, doi:10.1038/s41467-024-53173-w.
short: V. Pokusaeva, R.K. Satapathy, O. Symonova, M.A. Jösch, Nature Communications
15 (2024).
corr_author: '1'
date_created: 2024-10-20T22:02:05Z
date_published: 2024-10-12T00:00:00Z
date_updated: 2026-06-10T07:58:34Z
day: '12'
ddc:
- '570'
department:
- _id: MaJö
doi: 10.1038/s41467-024-53173-w
external_id:
isi:
- '001336422500001'
pmid:
- '39396050'
file:
- access_level: open_access
checksum: 2af4d6e7364329107aa94d072d594ce0
content_type: application/pdf
creator: dernst
date_created: 2024-10-21T12:11:10Z
date_updated: 2024-10-21T12:11:10Z
file_id: '18459'
file_name: 2024_NatureComm_Pokusaeva.pdf
file_size: 8276667
relation: main_file
success: 1
file_date_updated: 2024-10-21T12:11:10Z
fulldoi: https://doi.org/10.1038/s41467-024-53173-w
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 9B767A34-BA93-11EA-9121-9846C619BF3A
grant_number: '429960716'
name: Evolution of Sensorimotor Transformation Across Diptera
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '18568'
relation: dissertation_contains
status: public
- id: '17488'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Bilateral interactions of optic-flow sensitive neurons coordinate course control
in flies
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18451'
abstract:
- lang: eng
text: Inorganic nanoparticles can be assembled into superlattices with unique optical
and magnetic properties arising from collective behavior. Protein cages can be
utilized to guide this assembly by encapsulating nanoparticles and promoting their
assembly into ordered structures. However, creating ordered multi-component structures
with different protein cage types and sizes remains a challenge. Here, the co-crystallization
of two different protein cages (cowpea chlorotic mottle virus and ferritin) characterized
by opposing surface charges and unequal diameter is shown. Precise tuning of the
electrostatic attraction between the cages enabled the preparation of binary crystals
with dimensions up to several tens of micrometers. Additionally, binary metal
nanoparticle superlattices are achieved by loading gold and iron oxide nanoparticles
inside the cavities of the protein cages. The resulting structure adopts an AB2FCC
configuration that also impacts the dipolar coupling between the particles and
hence the optical properties of the crystals, providing key insight for the future
preparation of plasmonic and magnetic nanoparticle metamaterials.
acknowledgement: This work has received funding from the European Research Council
(ERC) under the European Union's Horizon 2020 research and innovation programme
(Grant Agreement No. 101002258). The authors acknowledge the provision of facilities
and technical support by Aalto University Bioeconomy Facilities and OtaNanoNanomicroscopy
Center (Aalto-NMC). This work was carried out under the Academy of Finland's Centers
of Excellence Programme, Life Inspired Hybrid Materials (LIBER) Center of Excellence
(2022–2029), project number 346110 and 346112.
article_number: '2408416'
article_processing_charge: Yes
article_type: original
author:
- first_name: Yu
full_name: Zhou, Yu
last_name: Zhou
- first_name: Ahmed
full_name: Shaukat, Ahmed
last_name: Shaukat
- first_name: Jani
full_name: Seitsonen, Jani
last_name: Seitsonen
- first_name: Carlo
full_name: Rigoni, Carlo
id: c5df3b62-5f9e-11ef-ba3c-b97f5b5b5ef0
last_name: Rigoni
- first_name: Jaakko V.I.
full_name: Timonen, Jaakko V.I.
last_name: Timonen
- first_name: Mauri A.
full_name: Kostiainen, Mauri A.
last_name: Kostiainen
citation:
ama: Zhou Y, Shaukat A, Seitsonen J, Rigoni C, Timonen JVI, Kostiainen MA. Protein
cage directed assembly of binary nanoparticle superlattices. Advanced Science.
2024;11(45). doi:10.1002/advs.202408416
apa: Zhou, Y., Shaukat, A., Seitsonen, J., Rigoni, C., Timonen, J. V. I., &
Kostiainen, M. A. (2024). Protein cage directed assembly of binary nanoparticle
superlattices. Advanced Science. Wiley. https://doi.org/10.1002/advs.202408416
chicago: Zhou, Yu, Ahmed Shaukat, Jani Seitsonen, Carlo Rigoni, Jaakko V.I. Timonen,
and Mauri A. Kostiainen. “Protein Cage Directed Assembly of Binary Nanoparticle
Superlattices.” Advanced Science. Wiley, 2024. https://doi.org/10.1002/advs.202408416.
ieee: Y. Zhou, A. Shaukat, J. Seitsonen, C. Rigoni, J. V. I. Timonen, and M. A.
Kostiainen, “Protein cage directed assembly of binary nanoparticle superlattices,”
Advanced Science, vol. 11, no. 45. Wiley, 2024.
ista: Zhou Y, Shaukat A, Seitsonen J, Rigoni C, Timonen JVI, Kostiainen MA. 2024.
Protein cage directed assembly of binary nanoparticle superlattices. Advanced
Science. 11(45), 2408416.
mla: Zhou, Yu, et al. “Protein Cage Directed Assembly of Binary Nanoparticle Superlattices.”
Advanced Science, vol. 11, no. 45, 2408416, Wiley, 2024, doi:10.1002/advs.202408416.
short: Y. Zhou, A. Shaukat, J. Seitsonen, C. Rigoni, J.V.I. Timonen, M.A. Kostiainen,
Advanced Science 11 (2024).
date_created: 2024-10-20T22:02:07Z
date_published: 2024-12-04T00:00:00Z
date_updated: 2025-09-08T14:20:31Z
day: '04'
ddc:
- '540'
department:
- _id: RaKl
doi: 10.1002/advs.202408416
external_id:
isi:
- '001330745600001'
pmid:
- '39401426'
file:
- access_level: open_access
checksum: 00451eeb2c9eecf1ff41ad243c793a51
content_type: application/pdf
creator: dernst
date_created: 2025-01-13T09:16:25Z
date_updated: 2025-01-13T09:16:25Z
file_id: '18834'
file_name: 2024_AdvancedScience_Zhou.pdf
file_size: 7040083
relation: main_file
success: 1
file_date_updated: 2025-01-13T09:16:25Z
fulldoi: https://doi.org/10.1002/advs.202408416
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '45'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Advanced Science
publication_identifier:
eissn:
- 2198-3844
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Protein cage directed assembly of binary nanoparticle superlattices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 11
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18465'
abstract:
- lang: eng
text: The phytohormone auxin is polarly transported in plants by PIN-FORMED (PIN)
transporters and controls virtually all growth and developmental processes. Canonical
PINs possess a long, largely disordered cytosolic loop. Auxin transport by canonical
PINs is activated by loop phosphorylation by certain kinases. The structure of
the PIN transmembrane domains was recently determined, their transport properties
remained poorly characterized, and the role of the loop in the transport process
was unclear. Here, we determined the quantitative kinetic parameters of auxin
transport mediated by Arabidopsis PINs to mathematically model auxin distribution
in roots and to test these predictions in vivo. Using chimeras between transmembrane
and loop domains of different PINs, we demonstrate a strong correlation between
transport parameters and physiological output, indicating that the loop domain
is not only required to activate PIN-mediated auxin transport, but it has an additional
role in the transport process by a currently unknown mechanism.
acknowledgement: This work was funded by DFG3468/6-1, DFG3468/6-3, and SFB924 to U.Z.H.
We thank Angela Alkofer and Helene Prunkl for excellent technical assistance and
Xenopus maintenance. Christian Luschnig is acknowledged for sharing unpublished
results and valuable discussions.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: DP
full_name: Janacek, DP
last_name: Janacek
- first_name: M
full_name: Kolb, M
last_name: Kolb
- first_name: L
full_name: Schulz, L
last_name: Schulz
- first_name: J
full_name: Mergner, J
last_name: Mergner
- first_name: B
full_name: Kuster, B
last_name: Kuster
- first_name: Matous
full_name: Glanc, Matous
id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
last_name: Glanc
orcid: 0000-0003-0619-7783
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: K
full_name: Ten Tusscher, K
last_name: Ten Tusscher
- first_name: C
full_name: Schwechheimer, C
last_name: Schwechheimer
- first_name: UZ
full_name: Hammes, UZ
last_name: Hammes
citation:
ama: Janacek D, Kolb M, Schulz L, et al. Transport properties of canonical PIN-FORMED
proteins from Arabidopsis and the role of the loop domain in auxin transport.
Developmental Cell. 2024;59(14):S1534-5807(24)00569-0. doi:10.1016/j.devcel.2024.09.020
apa: Janacek, D., Kolb, M., Schulz, L., Mergner, J., Kuster, B., Glanc, M., … Hammes,
U. (2024). Transport properties of canonical PIN-FORMED proteins from Arabidopsis
and the role of the loop domain in auxin transport. Developmental Cell.
Elsevier. https://doi.org/10.1016/j.devcel.2024.09.020
chicago: Janacek, DP, M Kolb, L Schulz, J Mergner, B Kuster, Matous Glanc, Jiří
Friml, K Ten Tusscher, C Schwechheimer, and UZ Hammes. “Transport Properties of
Canonical PIN-FORMED Proteins from Arabidopsis and the Role of the Loop Domain
in Auxin Transport.” Developmental Cell. Elsevier, 2024. https://doi.org/10.1016/j.devcel.2024.09.020.
ieee: D. Janacek et al., “Transport properties of canonical PIN-FORMED proteins
from Arabidopsis and the role of the loop domain in auxin transport,” Developmental
Cell, vol. 59, no. 14. Elsevier, pp. S1534-5807(24)00569–0, 2024.
ista: Janacek D, Kolb M, Schulz L, Mergner J, Kuster B, Glanc M, Friml J, Ten Tusscher
K, Schwechheimer C, Hammes U. 2024. Transport properties of canonical PIN-FORMED
proteins from Arabidopsis and the role of the loop domain in auxin transport.
Developmental Cell. 59(14), S1534-5807(24)00569–0.
mla: Janacek, DP, et al. “Transport Properties of Canonical PIN-FORMED Proteins
from Arabidopsis and the Role of the Loop Domain in Auxin Transport.” Developmental
Cell, vol. 59, no. 14, Elsevier, 2024, pp. S1534-5807(24)00569-0, doi:10.1016/j.devcel.2024.09.020.
short: D. Janacek, M. Kolb, L. Schulz, J. Mergner, B. Kuster, M. Glanc, J. Friml,
K. Ten Tusscher, C. Schwechheimer, U. Hammes, Developmental Cell 59 (2024) S1534-5807(24)00569–0.
date_created: 2024-10-23T08:41:27Z
date_published: 2024-12-16T00:00:00Z
date_updated: 2025-09-08T14:33:17Z
day: '16'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1016/j.devcel.2024.09.020
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isi: 1
issue: '14'
language:
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publication: Developmental Cell
publication_identifier:
eissn:
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issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transport properties of canonical PIN-FORMED proteins from Arabidopsis and
the role of the loop domain in auxin transport
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year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18483'
abstract:
- lang: eng
text: In this paper we prove a perturbative version of a remarkable Bialy–Mironov
(Ann. Math. 196(1):389–413, 2022) result. They prove non perturbative Birkhoff
conjecture for centrally-symmetric convex domains, namely, a centrally-symmetric
convex domain with integrable billiard is ellipse. We combine techniques from
Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) with a local result by Kaloshin–Sorrentino
(Ann. Math. 188(1):315–380, 2018) and show that a domain close enough to a centrally
symmetric one with integrable billiard is ellipse. To combine these results we
derive a slight extension of Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) by
proving that a notion of rational integrability is equivalent to the C0-integrability
condition used in their paper.
acknowledgement: We are grateful to the anonymous referee for their careful reading
and valuable remarks and comments which helped to improve significantly the paper.
Open access funding provided by Institute of Science and Technology (IST Austria).
V.K. and C.E.K. gratefully acknowledge support from the European Research Council
(ERC) through the Advanced Grant “SPERIG” (#885 707).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: Edmond
full_name: Koudjinan, Edmond
id: 52DF3E68-AEFA-11EA-95A4-124A3DDC885E
last_name: Koudjinan
orcid: 0000-0003-2640-4049
- first_name: Ke
full_name: Zhang, Ke
last_name: Zhang
citation:
ama: Kaloshin V, Koudjinan E, Zhang K. Birkhoff conjecture for nearly centrally
symmetric domains. Geometric and Functional Analysis. 2024;34:1973-2007.
doi:10.1007/s00039-024-00695-6
apa: Kaloshin, V., Koudjinan, E., & Zhang, K. (2024). Birkhoff conjecture for
nearly centrally symmetric domains. Geometric and Functional Analysis.
Springer Nature. https://doi.org/10.1007/s00039-024-00695-6
chicago: Kaloshin, Vadim, Edmond Koudjinan, and Ke Zhang. “Birkhoff Conjecture for
Nearly Centrally Symmetric Domains.” Geometric and Functional Analysis.
Springer Nature, 2024. https://doi.org/10.1007/s00039-024-00695-6.
ieee: V. Kaloshin, E. Koudjinan, and K. Zhang, “Birkhoff conjecture for nearly centrally
symmetric domains,” Geometric and Functional Analysis, vol. 34. Springer
Nature, pp. 1973–2007, 2024.
ista: Kaloshin V, Koudjinan E, Zhang K. 2024. Birkhoff conjecture for nearly centrally
symmetric domains. Geometric and Functional Analysis. 34, 1973–2007.
mla: Kaloshin, Vadim, et al. “Birkhoff Conjecture for Nearly Centrally Symmetric
Domains.” Geometric and Functional Analysis, vol. 34, Springer Nature,
2024, pp. 1973–2007, doi:10.1007/s00039-024-00695-6.
short: V. Kaloshin, E. Koudjinan, K. Zhang, Geometric and Functional Analysis 34
(2024) 1973–2007.
corr_author: '1'
date_created: 2024-10-27T23:01:45Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2025-09-08T14:27:45Z
day: '01'
ddc:
- '510'
department:
- _id: VaKa
doi: 10.1007/s00039-024-00695-6
ec_funded: 1
external_id:
arxiv:
- '2306.12301'
isi:
- '001329804200001'
file:
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checksum: e7fcd9f78beb40408c7d858ac0625e27
content_type: application/pdf
creator: dernst
date_created: 2025-01-13T09:14:24Z
date_updated: 2025-01-13T09:14:24Z
file_id: '18833'
file_name: 2024_GeometricFunctionalAnalysis_Kaloshin.pdf
file_size: 2260980
relation: main_file
success: 1
file_date_updated: 2025-01-13T09:14:24Z
fulldoi: https://doi.org/10.1007/s00039-024-00695-6
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isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 1973-2007
project:
- _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A
call_identifier: H2020
grant_number: '885707'
name: Spectral rigidity and integrability for billiards and geodesic flows
publication: Geometric and Functional Analysis
publication_identifier:
eissn:
- 1420-8970
issn:
- 1016-443X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Birkhoff conjecture for nearly centrally symmetric domains
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 34
year: '2024'
...
---
APC_amount: 3711,01 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18488'
abstract:
- lang: eng
text: The advancement of quantum simulators motivates the development of a theoretical
framework to assist with efficient state preparation in quantum many-body systems.
Generally, preparing a target entangled state via unitary evolution with time-dependent
couplings is a challenging task and very little is known about the existence of
solutions and their properties. In this work we develop a constructive approach
for preparing matrix product states (MPS) via continuous unitary evolution. We
provide an explicit construction of the operator that exactly implements the evolution
of a given MPS along a specified direction in its tangent space. This operator
can be written as a sum of local terms of finite range, yet it is in general non-Hermitian.
Relying on the explicit construction of the non-Hermitian generator of the dynamics,
we demonstrate the existence of a Hermitian sequence of operators that implements
the desired MPS evolution with an error that decreases exponentially with the
operator range. The construction is benchmarked on an explicit periodic trajectory
in a translationally invariant MPS manifold. We demonstrate that the Floquet unitary
generating the dynamics over one period of the trajectory features an approximate
MPS-like eigenstate embedded among a sea of thermalizing eigenstates. These results
show that our construction is not only useful for state preparation and control
of many-body systems, but also provides a generic route towards Floquet scars—periodically
driven models with quasilocal generators of dynamics that have exact MPS eigenstates
in their spectrum.
acknowledgement: We thank L. Piroli, S. Garratt, and A. Molnár for insightful discussions.
This research was funded in part by the European Research Council (ERC) under the
European Union’s Horizon 2020 research and innovation programme (Grant Agreements
No. 850899 and No. 863476), the Austrian Science Fund (FWF) (Grant DOIs 10.55776/COE1,
10.55776/P36305, and 10.55776/F71), and the European Union (NextGenerationEU). This
work was performed in part at the Aspen Center for Physics, which is supported by
National Science Foundation Grant PHY-2210452. This research was supported in part
by NSF Grant PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP).
article_number: '040311'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Marko
full_name: Ljubotina, Marko
id: F75EE9BE-5C90-11EA-905D-16643DDC885E
last_name: Ljubotina
orcid: 0000-0003-0038-7068
- first_name: Elena
full_name: Petrova, Elena
id: 0ac84990-897b-11ed-a09c-f5abb56a4ede
last_name: Petrova
- first_name: Norbert
full_name: Schuch, Norbert
last_name: Schuch
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
citation:
ama: Ljubotina M, Petrova E, Schuch N, Serbyn M. Tangent space generators of matrix
product states and exact floquet quantum scars. PRX Quantum. 2024;5(4).
doi:10.1103/prxquantum.5.040311
apa: Ljubotina, M., Petrova, E., Schuch, N., & Serbyn, M. (2024). Tangent space
generators of matrix product states and exact floquet quantum scars. PRX Quantum.
American Physical Society. https://doi.org/10.1103/prxquantum.5.040311
chicago: Ljubotina, Marko, Elena Petrova, Norbert Schuch, and Maksym Serbyn. “Tangent
Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX
Quantum. American Physical Society, 2024. https://doi.org/10.1103/prxquantum.5.040311.
ieee: M. Ljubotina, E. Petrova, N. Schuch, and M. Serbyn, “Tangent space generators
of matrix product states and exact floquet quantum scars,” PRX Quantum,
vol. 5, no. 4. American Physical Society, 2024.
ista: Ljubotina M, Petrova E, Schuch N, Serbyn M. 2024. Tangent space generators
of matrix product states and exact floquet quantum scars. PRX Quantum. 5(4), 040311.
mla: Ljubotina, Marko, et al. “Tangent Space Generators of Matrix Product States
and Exact Floquet Quantum Scars.” PRX Quantum, vol. 5, no. 4, 040311, American
Physical Society, 2024, doi:10.1103/prxquantum.5.040311.
short: M. Ljubotina, E. Petrova, N. Schuch, M. Serbyn, PRX Quantum 5 (2024).
corr_author: '1'
date_created: 2024-10-29T16:04:05Z
date_published: 2024-10-23T00:00:00Z
date_updated: 2025-09-08T14:26:29Z
day: '23'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/prxquantum.5.040311
ec_funded: 1
external_id:
arxiv:
- '2403.12325'
isi:
- '001346198800001'
file:
- access_level: open_access
checksum: 2e057ba021744d0a74602517935326b3
content_type: application/pdf
creator: dernst
date_created: 2024-10-30T08:59:09Z
date_updated: 2024-10-30T08:59:09Z
file_id: '18489'
file_name: 2024_PRXQuantum_Ljubotina.pdf
file_size: 1151431
relation: main_file
success: 1
file_date_updated: 2024-10-30T08:59:09Z
fulldoi: https://doi.org/10.1103/prxquantum.5.040311
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '4'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '850899'
name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: PRX Quantum
publication_identifier:
eissn:
- 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tangent space generators of matrix product states and exact floquet quantum
scars
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18490'
abstract:
- lang: eng
text: 'For large classes of even-dimensional Riemannian manifolds (Formula presented.),
we construct and analyze conformally invariant random fields. These centered Gaussian
fields (Formula presented.), called co-polyharmonic Gaussian fields, are characterized
by their covariance kernels k which exhibit a precise logarithmic divergence:
(Formula presented.). They share a fundamental quasi-invariance property under
conformal transformations. In terms of the co-polyharmonic Gaussian field (Formula
presented.), we define the Liouville Quantum Gravity measure, a random measure
on (Formula presented.), heuristically given as (Formula presented.) and rigorously
obtained as almost sure weak limit of the right-hand side with (Formula presented.)
replaced by suitable regular approximations (Formula presented.). In terms on
the Liouville Quantum Gravity measure, we define the Liouville Brownian motion
on (Formula presented.) and the random GJMS operators. Finally, we present an
approach to a conformal field theory in arbitrary even dimension with an ansatz
based on Branson''s (Formula presented.) -curvature: we give a rigorous meaning
to the Polyakov–Liouville measure (Formula presented.) and we derive the corresponding
conformal anomaly. The set of admissible manifolds is conformally invariant. It
includes all compact 2-dimensional Riemannian manifolds, all compact non-negatively
curved Einstein manifolds of even dimension, and large classes of compact hyperbolic
manifolds of even dimension. However, not every compact even-dimensional Riemannian
manifold is admissible. Our results concerning the logarithmic divergence of the
kernel (Formula presented.) rely on new sharp estimates for heat kernels and higher
order Green kernels on arbitrary closed manifolds. '
acknowledgement: The authors are grateful to Masha Gordina for helpful references,
and to Nathanaël Berestycki, Baptiste Cerclé, and Ewain Gwynne for valuable comments
on the first circulated version of this paper. They also would like to thank Sebastian
Andres, Peter Friz, and Yizheng Yuan for pointing out an erroneous formulation in
the previous version of Theorem 5.7. Moreover, KTS would liketo express his thanks
to Sebastian Andres, Matthias Erbar, Martin Huesmann, and Jan Mass for stimulating
discussions on previous attempts to this project. LDS gratefully acknowledges financial
support from the European Research Council (grant agreement No 716117, awarded to
J. Maas), from the Austrian Science Fund (FWF) project 10.55776/ESP208, and from
the Austrian Science Fund (FWF) project 10.55776/F65.RH, EK, and KTS gratefully
acknowledge funding by the Deutsche Forschungsgemeinschaft through the project “Random
Riemannian Geometry” within the SPP 2265 “Random Geomet-ric Systems,” through the
Hausdorff Center for Mathematics (project ID 390685813), and through project B03
within the CRC 1060 (project ID 211504053). RH and KTS also gratefully acknowledge
financial support from the European Research Council through the ERC AdG “RicciBounds”(grant
agreement 694405).Data sharing not applicable to this article as no datasets were
generated or analyzed during the current study. Open access funding enabled and
organized by Projekt DEAL.
article_number: e70003
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lorenzo
full_name: Dello Schiavo, Lorenzo
id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
last_name: Dello Schiavo
orcid: 0000-0002-9881-6870
- first_name: Ronan
full_name: Herry, Ronan
last_name: Herry
- first_name: Eva
full_name: Kopfer, Eva
last_name: Kopfer
- first_name: Karl Theodor
full_name: Sturm, Karl Theodor
last_name: Sturm
citation:
ama: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. Conformally invariant random
fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian
manifolds of even dimension. Journal of the London Mathematical Society.
2024;110(5). doi:10.1112/jlms.70003
apa: Dello Schiavo, L., Herry, R., Kopfer, E., & Sturm, K. T. (2024). Conformally
invariant random fields, Liouville quantum gravity measures, and random Paneitz
operators on Riemannian manifolds of even dimension. Journal of the London
Mathematical Society. London Mathematical Society. https://doi.org/10.1112/jlms.70003
chicago: Dello Schiavo, Lorenzo, Ronan Herry, Eva Kopfer, and Karl Theodor Sturm.
“Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and
Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal
of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/jlms.70003.
ieee: L. Dello Schiavo, R. Herry, E. Kopfer, and K. T. Sturm, “Conformally invariant
random fields, Liouville quantum gravity measures, and random Paneitz operators
on Riemannian manifolds of even dimension,” Journal of the London Mathematical
Society, vol. 110, no. 5. London Mathematical Society, 2024.
ista: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. 2024. Conformally invariant
random fields, Liouville quantum gravity measures, and random Paneitz operators
on Riemannian manifolds of even dimension. Journal of the London Mathematical
Society. 110(5), e70003.
mla: Dello Schiavo, Lorenzo, et al. “Conformally Invariant Random Fields, Liouville
Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds
of Even Dimension.” Journal of the London Mathematical Society, vol. 110,
no. 5, e70003, London Mathematical Society, 2024, doi:10.1112/jlms.70003.
short: L. Dello Schiavo, R. Herry, E. Kopfer, K.T. Sturm, Journal of the London
Mathematical Society 110 (2024).
date_created: 2024-11-03T23:01:44Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2025-09-08T14:29:45Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1112/jlms.70003
ec_funded: 1
external_id:
isi:
- '001351918100029'
file:
- access_level: open_access
checksum: 143816823b5f43bd3748da8e3e91cef5
content_type: application/pdf
creator: dernst
date_created: 2024-11-04T08:54:26Z
date_updated: 2024-11-04T08:54:26Z
file_id: '18497'
file_name: 2024_JourLondonMathSoc_Schiavo.pdf
file_size: 911476
relation: main_file
success: 1
file_date_updated: 2024-11-04T08:54:26Z
fulldoi: https://doi.org/10.1112/jlms.70003
has_accepted_license: '1'
intvolume: ' 110'
isi: 1
issue: '5'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c
grant_number: E208
name: Configuration Spaces over Non-Smooth Spaces
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
publication: Journal of the London Mathematical Society
publication_identifier:
eissn:
- 1469-7750
issn:
- 0024-6107
publication_status: published
publisher: London Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Conformally invariant random fields, Liouville quantum gravity measures, and
random Paneitz operators on Riemannian manifolds of even dimension
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 110
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18494'
abstract:
- lang: eng
text: We expect luminous (M 1450 ≲ −26.5) high-redshift quasars to trace the highest-density
peaks in the early Universe. Here, we present observations of four z ≳ 6 quasar
fields using JWST/NIRCam in the imaging and wide-field slitless spectroscopy mode
and report a wide range in the number of detected [O iii]-emitting galaxies in
the quasars’ environments, ranging between a density enhancement of δ ≈ 65 within
a 2 cMpc radius—one of the largest protoclusters during the Epoch of Reionization
discovered to date—to a density contrast consistent with zero, indicating the
presence of a UV-luminous quasar in a region comparable to the average density
of the Universe. By measuring the two-point cross-correlation function of quasars
and their surrounding galaxies, as well as the galaxy autocorrelation function,
we infer a correlation length of quasars at 〈z〉 = 6.25 of r 0 QQ = 22.0 − 2.9
+ 3.0 cMpc h − 1 , while we obtain a correlation length of the [O iii]-emitting
galaxies of r 0 GG = 4.1 ± 0.3 cMpc h − 1 . By comparing the correlation functions
to dark-matter-only simulations we estimate the minimum mass of the quasars’ host
dark matter halos to be log 10 ( M halo , min / M ⊙ ) = 12.43 − 0.15 + 0.13 (and
log 10 ( M halo , min [ OIII ] / M ⊙ ) = 10.56 − 0.03 + 0.05 for the [O iii] emitters),
indicating that (a) luminous quasars do not necessarily reside within the most
overdense regions in the early Universe, and that (b) the UV-luminous duty cycle
of quasar activity at these redshifts is f duty ≪ 1. Such short quasar activity
timescales challenge our understanding of early supermassive black hole growth
and provide evidence for highly dust-obscured growth phases or episodic, radiatively
inefficient accretion rates.
acknowledgement: "The authors would like to thank the anonymous referee for the thoughtful
comments, which significantly improved our manuscript, and Jan-Torge Schindler,
Jiamu Huang, and Feige Wang for helpful discussions.\r\n\r\nJ.F.H. and E.P. acknowledge
support from the European Research Council (ERC) under the European Unions Horizon
2020 research and innovation program (grant agreement No. 885301). J.M. acknowledges
support from the European Union (ERC, AGENTS, 101076224).\r\n\r\nThis work is based
on observations made with the NASA/ESA/CSA James Webb Space Telescope. The JWST
data presented in this article were obtained from the Mikulski Archive for Space
Telescopes at the Space Telescope Science Institute, which is operated by the Association
of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127
for JWST. The specific observations analyzed are associated with program #1243 and
can be accessed via doi:10.17909/m5mp-5v90.\r\n\r\nThis work used the DiRAC Memory
Intensive service (Cosma8) at the University of Durham, which is part of the STFC
DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through
a Directors Discretionary Time allocation in 2023/24, under the auspices of the
UKRI-funded DiRAC Federation Project. The equipment was funded by BEIS capital funding
via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1,
Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National
e-Infrastructure.\r\n\r\nWe thank the Instituto de Astrofisica de Andalucia (IAA-CSIC),
Centro de Supercomputacion de Galicia (CESGA), and Spanish Academic and Research
Network (RedIRIS) in Spain for hosting Uchuu DR1, DR2, and DR3 in the Skies & Universes
site for cosmological simulations. The Uchuu simulations were carried out on the
Aterui II supercomputer at the Center for Computational Astrophysics, CfCA, of the
National Astronomical Observatory of Japan, and the K computer at the RIKEN Advanced
Institute for Computational Science. The Uchuu Data Releases efforts have made use
of the skunIAA_RedIRIS and skun6IAA computer facilities managed by the IAA-CSIC
in Spain (MICINN EU-Feder grant EQC2018-004366-P)."
article_number: '275'
article_processing_charge: Yes
article_type: original
author:
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Ruari
full_name: Mackenzie, Ruari
last_name: Mackenzie
- first_name: Elia
full_name: Pizzati, Elia
last_name: Pizzati
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Joseph F.
full_name: Hennawi, Joseph F.
last_name: Hennawi
- first_name: Haowen
full_name: Zhang, Haowen
last_name: Zhang
- first_name: Rongmon
full_name: Bordoloi, Rongmon
last_name: Bordoloi
- first_name: Daichi
full_name: Kashino, Daichi
last_name: Kashino
- first_name: Simon J.
full_name: Lilly, Simon J.
last_name: Lilly
- first_name: Rohan P.
full_name: Naidu, Rohan P.
last_name: Naidu
- first_name: Robert A.
full_name: Simcoe, Robert A.
last_name: Simcoe
- first_name: Minghao
full_name: Yue, Minghao
last_name: Yue
- first_name: Carlos S.
full_name: Frenk, Carlos S.
last_name: Frenk
- first_name: John C.
full_name: Helly, John C.
last_name: Helly
- first_name: Matthieu
full_name: Schaller, Matthieu
last_name: Schaller
- first_name: Joop
full_name: Schaye, Joop
last_name: Schaye
citation:
ama: Eilers AC, Mackenzie R, Pizzati E, et al. EIGER. VI. The correlation function,
host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical
Journal. 2024;974(2). doi:10.3847/1538-4357/ad778b
apa: Eilers, A. C., Mackenzie, R., Pizzati, E., Matthee, J. J., Hennawi, J. F.,
Zhang, H., … Schaye, J. (2024). EIGER. VI. The correlation function, host halo
mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal.
IOP Publishing. https://doi.org/10.3847/1538-4357/ad778b
chicago: Eilers, Anna Christina, Ruari Mackenzie, Elia Pizzati, Jorryt J Matthee,
Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, et al. “EIGER. VI. The Correlation
Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical
Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778b.
ieee: A. C. Eilers et al., “EIGER. VI. The correlation function, host halo
mass, and duty cycle of luminous quasars at z ≳ 6,” Astrophysical Journal,
vol. 974, no. 2. IOP Publishing, 2024.
ista: Eilers AC, Mackenzie R, Pizzati E, Matthee JJ, Hennawi JF, Zhang H, Bordoloi
R, Kashino D, Lilly SJ, Naidu RP, Simcoe RA, Yue M, Frenk CS, Helly JC, Schaller
M, Schaye J. 2024. EIGER. VI. The correlation function, host halo mass, and duty
cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 974(2), 275.
mla: Eilers, Anna Christina, et al. “EIGER. VI. The Correlation Function, Host Halo
Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal,
vol. 974, no. 2, 275, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778b.
short: A.C. Eilers, R. Mackenzie, E. Pizzati, J.J. Matthee, J.F. Hennawi, H. Zhang,
R. Bordoloi, D. Kashino, S.J. Lilly, R.P. Naidu, R.A. Simcoe, M. Yue, C.S. Frenk,
J.C. Helly, M. Schaller, J. Schaye, Astrophysical Journal 974 (2024).
date_created: 2024-11-03T23:01:45Z
date_published: 2024-10-01T00:00:00Z
date_updated: 2025-09-08T14:29:05Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/ad778b
external_id:
isi:
- '001338877100001'
file:
- access_level: open_access
checksum: 1fcac3d11d01d91cf2bb4963b6e10b22
content_type: application/pdf
creator: dernst
date_created: 2024-11-04T08:42:23Z
date_updated: 2024-11-04T08:42:23Z
file_id: '18496'
file_name: 2024_AstrophysicalJour_Eilers.pdf
file_size: 1042470
relation: main_file
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file_date_updated: 2024-11-04T08:42:23Z
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has_accepted_license: '1'
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isi: 1
issue: '2'
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- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
grant_number: '101076224'
name: Young galaxies as tracers and agents of cosmic reionization
publication: Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous
quasars at z ≳ 6
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 974
year: '2024'
...
---
OA_place: repository
_id: '18498'
abstract:
- lang: eng
text: 'Scripts and data used in the research study Predicting rapid adaptation in
time from adaptation in space: a 30-year field experiment in marine snails. https://doi.org/10.1101/2023.09.27.559715'
article_processing_charge: No
author:
- first_name: Diego Fernando
full_name: Garcia Castillo, Diego Fernando
id: ae681a14-dc74-11ea-a0a7-c6ef18161701
last_name: Garcia Castillo
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Jenny
full_name: Larsson, Jenny
last_name: Larsson
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Data and code for: Predicting
rapid adaptation in time from adaptation in space: a 30-year field experiment
in marine snails. 2024. doi:10.5281/ZENODO.12159343'
apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski,
S., Butlin, R., … Westram, A. M. (2024). Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails.
Zenodo. https://doi.org/10.5281/ZENODO.12159343'
chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson,
Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Data
and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A
30-Year Field Experiment in Marine Snails.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.12159343.'
ieee: 'D. F. Garcia Castillo et al., “Data and code for: Predicting rapid
adaptation in time from adaptation in space: a 30-year field experiment in marine
snails.” Zenodo, 2024.'
ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R,
Johannesson K, Westram AM. 2024. Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails,
Zenodo, 10.5281/ZENODO.12159343.'
mla: 'Garcia Castillo, Diego Fernando, et al. Data and Code for: Predicting Rapid
Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine
Snails. Zenodo, 2024, doi:10.5281/ZENODO.12159343.'
short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R.
Butlin, K. Johannesson, A.M. Westram, (2024).
corr_author: '1'
date_created: 2024-11-04T09:33:17Z
date_published: 2024-06-19T00:00:00Z
date_updated: 2026-04-16T12:20:37Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5281/ZENODO.12159343
fulldoi: https://doi.org/10.5281/ZENODO.12159343
has_accepted_license: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.12159344
month: '06'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '20991'
relation: used_in_publication
status: public
- id: '18491'
relation: used_in_publication
status: public
status: public
title: 'Data and code for: Predicting rapid adaptation in time from adaptation in
space: a 30-year field experiment in marine snails'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: repository
OA_type: free access
_id: '18503'
abstract:
- lang: eng
text: "In 1996, Karger [Kar96] gave a startling randomized algorithm that finds
a minimum-cut in a (weighted) graph in time O(m log3 n) which he termed near-linear
time meaning linear (in the size of the input) times a polylogarthmic factor.
In this paper, we give the first deterministic algorithm which runs in near-linear
time for weighted graphs.\r\nPreviously, the breakthrough results of Kawarabayashi
and Thorup [KT19] gave a near-linear time algorithm for simple graphs (which was
improved to have running time O(m log2 n log log n) in [HRW20].) The main technique
here is a clustering procedure that perfectly preserves minimum cuts. Recently,
Li [Li21] gave an m1+o(1) deterministic minimum-cut algorithm for weighted graphs;
this form of running time has been termed “almost-linear”. Li uses almost-linear
time deterministic expander decompositions which do not perfectly preserve minimum
cuts, but he can use these clusterings to, in a sense, “derandomize” the methods
of Karger.\r\nIn terms of techniques, we provide a structural theorem that says
there exists a sparse clustering that preserves minimum cuts in a weighted graph
with o(1) error. In addition, we construct it deterministically in near linear
time. This was done exactly for simple graphs in [KT19, HRW20] and with polylogarithmic
error for weighted graphs in [Li21]. Extending the techniques in [KT19, HRW20]
to weighted graphs presents significant challenges, and moreover, the algorithm
can only polylogarithmically approximately preserve minimum cuts. A remaining
challenge is to reduce the polylogarithmic-approximate clusterings to 1 + o(1/
log n)-approximate so that they can be applied recursively as in [Li21] over O(log
n) many levels. This is an additional challenge that requires building on properties
of tree-packings in the presence of a wide range of edge weights to, for example,
find sources for local flow computations which identify minimum cuts that cross
clusters."
acknowledgement: This project has received funding from the European Research Council(ERC)
under the European Union’s Horizon 2020 research and innovation programme (Grant
agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDyn-Struct)”
and the Austrian Science Fund (FWF) project Z 422-N, project “Static and Dynamic
Hierarchical Graph Decompositions”, I 5982-N, and project “Fast Algorithms for a
Reactive Network Layer (ReactNet)”, P33775-N, with additional funding from the netidee
SCIENCE Stiftung, 2020–2024.
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Jason
full_name: Li, Jason
last_name: Li
- first_name: Satish
full_name: Rao, Satish
last_name: Rao
- first_name: Di
full_name: Wang, Di
last_name: Wang
citation:
ama: 'Henzinger M, Li J, Rao S, Wang D. Deterministic near-linear time minimum cut
in weighted graphs. In: 35th Annual ACM-SIAM Symposium on Discrete Algorithms.
Society for Industrial and Applied Mathematics; 2024:3089-3139. doi:10.1137/1.9781611977912.111'
apa: 'Henzinger, M., Li, J., Rao, S., & Wang, D. (2024). Deterministic near-linear
time minimum cut in weighted graphs. In 35th Annual ACM-SIAM Symposium on Discrete
Algorithms (pp. 3089–3139). Alexandria, VA, United States: Society for Industrial
and Applied Mathematics. https://doi.org/10.1137/1.9781611977912.111'
chicago: Henzinger, Monika, Jason Li, Satish Rao, and Di Wang. “Deterministic Near-Linear
Time Minimum Cut in Weighted Graphs.” In 35th Annual ACM-SIAM Symposium on
Discrete Algorithms, 3089–3139. Society for Industrial and Applied Mathematics,
2024. https://doi.org/10.1137/1.9781611977912.111.
ieee: M. Henzinger, J. Li, S. Rao, and D. Wang, “Deterministic near-linear time
minimum cut in weighted graphs,” in 35th Annual ACM-SIAM Symposium on Discrete
Algorithms, Alexandria, VA, United States, 2024, pp. 3089–3139.
ista: 'Henzinger M, Li J, Rao S, Wang D. 2024. Deterministic near-linear time minimum
cut in weighted graphs. 35th Annual ACM-SIAM Symposium on Discrete Algorithms.
SODA: Symposium on Discrete Algorithms, 3089–3139.'
mla: Henzinger, Monika, et al. “Deterministic Near-Linear Time Minimum Cut in Weighted
Graphs.” 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society
for Industrial and Applied Mathematics, 2024, pp. 3089–139, doi:10.1137/1.9781611977912.111.
short: M. Henzinger, J. Li, S. Rao, D. Wang, in:, 35th Annual ACM-SIAM Symposium
on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024,
pp. 3089–3139.
conference:
end_date: 2024-01-10
location: Alexandria, VA, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2024-01-07
corr_author: '1'
date_created: 2024-11-04T10:54:21Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-06-24T12:09:26Z
day: '04'
department:
- _id: MoHe
doi: 10.1137/1.9781611977912.111
ec_funded: 1
external_id:
arxiv:
- '2401.05627'
fulldoi: https://doi.org/10.1137/1.9781611977912.111
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2401.05627
month: '01'
oa: 1
oa_version: Preprint
page: 3089-3139
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
call_identifier: H2020
grant_number: '101019564'
name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
grant_number: Z00422
name: Efficient algorithms
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
grant_number: I05982
name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
grant_number: P33775
name: Fast Algorithms for a Reactive Network Layer
publication: 35th Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
eisbn:
- '9781611977912'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deterministic near-linear time minimum cut in weighted graphs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: publisher
OA_type: gold
_id: '18515'
abstract:
- lang: eng
text: "Understanding the role of evolutionary processes in shaping genetic variation
has been a\r\nprimary goal in evolutionary genetics. In this regard, a key question
is how genetically\r\ndistinct populations evolve in the face of gene flow, thereby
generating genetic and\r\nphenotypic divergence and reproductive isolation (RI).
This requires quantifying the role\r\nand relative contributions of prezygotic
and postzygotic isolating mechanisms on the\r\nreduction of gene exchange between
populations, and identifying regions in the genome\r\nthat mediate RI, which is
often polygenic. Further, this needs distinguishing neutral and\r\nselected regions
in the genome, and discerning how selection influences patterns of neutral\r\ndivergence.\r\nPopulation
structure, defined as any deviation from panmixia, such as geographic distribution,
movement and mating patterns of individuals, influences how genetic variation
is\r\nstructured in space and shapes the neutral null model. Availability of large
scale spatial\r\ngenomic datasets now enables us to detect signatures of population
structure in genetic\r\ndata and infer population genetic parameters. Such inferences
are crucial and have wide\r\napplications in biodiversity, conservation genetics,
population management and medical\r\ngenetics. However, inferences are based on
assumptions that do not always match the\r\ncomplex reality, thus leading to erroneous
conclusions. Moreover, the role and interaction\r\nof heterogeneous population
density and dispersal, which are ubiquitous in nature, has\r\nbeen challenging
to study owing to their mathematical complexity. In such scenarios,\r\nfeedback
between theory, data and simulations can prove to be useful.\r\nIn this thesis,
I examine the effect of population structure on neutral genetic variation\r\nand
barriers to gene exchange in hybridising populations, thereby bridging together
the\r\nfields of spatial population genetics and speciation.\r\nDespite being
a key concept in speciation, reproductive isolation (RI) lacks a quantitative\r\ndefinition
and has been used and measured differently across different fields. Chapter 2\r\ngives
a quantitative definition of RI, in terms of the effect of genetic differences
on gene\r\nflow. We give analytical predictions for RI in a range of scenarios,
in terms of effective migration rates for discrete populations and barrier strength
for continuous populations.\r\nIn addition to this, we discuss current measures
of RI and their limitations, and propose\r\nthe need for new measures that combine
organismal and genetic perspectives of RI.\r\nIn chapter 3, I examine the combined
effect of assortative mating, sexual selection\r\nand viability selection on RI.
For this, we consider a polygenic ‘magic’ trait under a\r\nmainland-island model.
We obtain novel theoretical predictions for molecular divergence\r\nin terms of
effective migration rates, which bears a simple relationship to measurable\r\nfitness
components of migrants and various early generation hybrids. We explore the\r\nconditions
under which local adaptation can be maintained despite maladaptive gene flow\r\nand
quantify the relative contributions of viability and sexual selection to genome-wide\r\nbarriers
to gene flow.\r\nThe next two chapters of the thesis focus on a hybrid zone of
Antirrhinum majus that\r\nconsist of two subspecies- the magenta flowered A. m.
pseudomajus and the yellow\r\nflowered A.m. striatum. Previous studies have suggested
that flower colour is target of\r\npollinator mediated selection and is influenced
only by few genes. While these regions\r\nshow high genetic differentiation between
the subspecies, the rest of the genome is seen\r\nto be well mixed. Chapter 4
examines the effects of heterogeneous population density\r\nand leptokurtic dispersal
on isolation by distance and the distribution of heterozygosity\r\nby focusing
on non-flower colour markers.\r\nChapter 5 analyses cline shapes and associations
among 6 focal flower colour markers to\r\nunderstand how selection and dispersal
maintain this hybrid zone. We see sharp coincident\r\nstepped clines at all loci
and positive associations throughout the hybrid zone, contrary to\r\nthe expected
patterns from diffusive gene flow. With a novel scheme of inferring dispersal\r\ncombined
with multilocus simulations, we show that stepped clines do not reflect genetic\r\nbarriers
to gene flow, but are rather a result of long-distance migration. This framework\r\nallows
us to get realistic estimates gene flow and selection and shows how traditional
cline\r\nanalysis may lead to inaccurate conclusions when assumptions of the theory
are not met.\r\nOverall, this thesis investigates how different features of population
structure leave\r\ndetectable signatures in genetic variation, namely in patterns
of isolation by distance,\r\nlinkage disequilibrium and genetic divergence. It
also highlights how effective migration\r\nrates provide useful way of analysing
polygenic architectures and shed new light into\r\nhybrid zones. In doing so,
I identify scenarios when simple models become insufficient\r\nand suggest possibe
directions by combining genetic data with simulations."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "I also acknowledge the funding agencies Marie Curie COFUND Doctoral
Fellowship,\r\nAustrian Science Fund FWF (grant P32166) and ERC (grant PR1000ERC02)
for financially\r\nsupporting my research over the years."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Parvathy
full_name: Surendranadh, Parvathy
id: 455235B8-F248-11E8-B48F-1D18A9856A87
last_name: Surendranadh
orcid: 0000-0001-6395-386X
citation:
ama: Surendranadh P. Effect of population structure on neutral genetic variation
and barriers to gene exchange. 2024. doi:10.15479/at:ista:18515
apa: Surendranadh, P. (2024). Effect of population structure on neutral genetic
variation and barriers to gene exchange. Institute of Science and Technology
Austria. https://doi.org/10.15479/at:ista:18515
chicago: Surendranadh, Parvathy. “Effect of Population Structure on Neutral Genetic
Variation and Barriers to Gene Exchange.” Institute of Science and Technology
Austria, 2024. https://doi.org/10.15479/at:ista:18515.
ieee: P. Surendranadh, “Effect of population structure on neutral genetic variation
and barriers to gene exchange,” Institute of Science and Technology Austria, 2024.
ista: Surendranadh P. 2024. Effect of population structure on neutral genetic variation
and barriers to gene exchange. Institute of Science and Technology Austria.
mla: Surendranadh, Parvathy. Effect of Population Structure on Neutral Genetic
Variation and Barriers to Gene Exchange. Institute of Science and Technology
Austria, 2024, doi:10.15479/at:ista:18515.
short: P. Surendranadh, Effect of Population Structure on Neutral Genetic Variation
and Barriers to Gene Exchange, Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2024-11-06T21:25:37Z
date_published: 2024-11-07T00:00:00Z
date_updated: 2026-04-07T12:56:52Z
day: '07'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: NiBa
doi: 10.15479/at:ista:18515
file:
- access_level: open_access
checksum: c32cf7bc75748d9c551d8eb70178bbec
content_type: application/pdf
creator: psurendr
date_created: 2024-11-07T10:59:29Z
date_updated: 2024-11-07T10:59:29Z
file_id: '18519'
file_name: PhD_Thesis__Parvathy_071124_PDFA.pdf
file_size: 37019760
relation: main_file
success: 1
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checksum: 4417e02d54084d89e75734e18caaa96d
content_type: application/zip
creator: psurendr
date_created: 2024-11-07T10:59:42Z
date_updated: 2024-11-07T10:59:42Z
file_id: '18520'
file_name: PhD Thesis- Parvathy_071124.zip
file_size: 41198857
relation: source_file
file_date_updated: 2024-11-07T10:59:42Z
fulldoi: https://doi.org/10.15479/at:ista:18515
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: '219'
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
grant_number: P32166
name: Snapdragon Speciation
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
grant_number: '101055327'
name: Understanding the evolution of continuous genomes
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
title: Effect of population structure on neutral genetic variation and barriers to
gene exchange
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
APC_amount: 2748 EUR
OA_place: publisher
OA_type: hybrid
_id: '18521'
abstract:
- lang: eng
text: In distributed systems with processes that do not share a global clock, partial
synchrony is achieved by clock synchronization that guarantees bounded clock skew
among all applications. Existing solutions for distributed runtime verification
under partial synchrony against temporal logic specifications are exact but suffer
from significant computational overhead. In this paper, we propose an approximate
distributed monitoring algorithm for Signal Temporal Logic (STL) that mitigates
this issue by abstracting away potential interleaving behaviors. This conservative
abstraction enables a significant speedup of the distributed monitors, albeit
with a tradeoff in accuracy. We address this tradeoff with a methodology that
combines our approximate monitor with its exact counterpart, resulting in enhanced
efficiency without sacrificing precision. We evaluate our approach with multiple
experiments, showcasing its efficacy in both real-world applications and synthetic
examples.
acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. This
work is sponsored in part by the United States NSF CCF-2118356 award. This research
was partially funded by A-IQ Ready (Chips JU, grant agreement No. 101096658).
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
arxiv: 1
author:
- first_name: Borzoo
full_name: Bonakdarpour, Borzoo
last_name: Bonakdarpour
- first_name: Anik
full_name: Momtaz, Anik
last_name: Momtaz
- first_name: Dejan
full_name: Nickovic, Dejan
id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
last_name: Nickovic
- first_name: Naci E
full_name: Sarac, Naci E
id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425
last_name: Sarac
citation:
ama: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. Approximate distributed monitoring
under partial synchrony: Balancing speed & accuracy. In: 24th International
Conference on Runtime Verification. Vol 15191. Springer Nature; 2024:282-301.
doi:10.1007/978-3-031-74234-7_18'
apa: 'Bonakdarpour, B., Momtaz, A., Nickovic, D., & Sarac, N. E. (2024). Approximate
distributed monitoring under partial synchrony: Balancing speed & accuracy.
In 24th International Conference on Runtime Verification (Vol. 15191, pp.
282–301). Istanbul, Turkey: Springer Nature. https://doi.org/10.1007/978-3-031-74234-7_18'
chicago: 'Bonakdarpour, Borzoo, Anik Momtaz, Dejan Nickovic, and Naci E Sarac. “Approximate
Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.”
In 24th International Conference on Runtime Verification, 15191:282–301.
Springer Nature, 2024. https://doi.org/10.1007/978-3-031-74234-7_18.'
ieee: 'B. Bonakdarpour, A. Momtaz, D. Nickovic, and N. E. Sarac, “Approximate distributed
monitoring under partial synchrony: Balancing speed & accuracy,” in 24th
International Conference on Runtime Verification, Istanbul, Turkey, 2024,
vol. 15191, pp. 282–301.'
ista: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. 2024. Approximate distributed
monitoring under partial synchrony: Balancing speed & accuracy. 24th International
Conference on Runtime Verification. RV: Conference on Runtime Verification, LNCS,
vol. 15191, 282–301.'
mla: 'Bonakdarpour, Borzoo, et al. “Approximate Distributed Monitoring under Partial
Synchrony: Balancing Speed & Accuracy.” 24th International Conference on
Runtime Verification, vol. 15191, Springer Nature, 2024, pp. 282–301, doi:10.1007/978-3-031-74234-7_18.'
short: B. Bonakdarpour, A. Momtaz, D. Nickovic, N.E. Sarac, in:, 24th International
Conference on Runtime Verification, Springer Nature, 2024, pp. 282–301.
conference:
end_date: 2024-10-17
location: Istanbul, Turkey
name: 'RV: Conference on Runtime Verification'
start_date: 2024-10-15
corr_author: '1'
date_created: 2024-11-10T23:01:58Z
date_published: 2024-10-12T00:00:00Z
date_updated: 2026-05-20T08:43:20Z
day: '12'
ddc:
- '000'
department:
- _id: ToHe
- _id: GradSch
doi: 10.1007/978-3-031-74234-7_18
ec_funded: 1
external_id:
arxiv:
- '2408.05033'
isi:
- '001420093700018'
file:
- access_level: open_access
checksum: 7b8ca21b8c19ab796fa445b0e54003ca
content_type: application/pdf
creator: dernst
date_created: 2024-11-11T09:42:28Z
date_updated: 2024-11-11T09:42:28Z
file_id: '18539'
file_name: 2024_LNCS_Bonakdarpour.pdf
file_size: 1897101
relation: main_file
success: 1
file_date_updated: 2024-11-11T09:42:28Z
fulldoi: https://doi.org/10.1007/978-3-031-74234-7_18
has_accepted_license: '1'
intvolume: ' 15191'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 282-301
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
call_identifier: H2020
grant_number: '101020093'
name: Vigilant Algorithmic Monitoring of Software
publication: 24th International Conference on Runtime Verification
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783031742330'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Approximate distributed monitoring under partial synchrony: Balancing speed
& accuracy'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15191
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18522'
abstract:
- lang: eng
text: The Golgi apparatus is essential for protein sorting, yet its quality control
mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex
uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic length
of α-helical transmembrane domains (TMDs) at the Golgi. Thereby the Dsc complex
likely interacts with orphaned ER and Golgi proteins that have shorter TMDs and
ubiquitinates them for targeted degradation. Some Dsc substrates will be extracted
by Cdc48 for endosome and Golgi associated proteasomal degradation (EGAD), while
others will undergo ESCRT dependent vacuolar degradation. Some substrates are
degraded by both, EGAD- or ESCRT pathways. The accumulation of Dsc substrates
entails a specific increase in glycerophospholipids with shorter and asymmetric
fatty acyl chains. Hence, the Dsc complex mediates the selective degradation of
orphaned proteins at the sorting center of cells, which prevents their spreading
across other organelles and thereby preserves cellular membrane protein and lipid
composition.
acknowledgement: 'We thank Snezhana Oliferenko, Hesso Farhan, Chris Dunworth, and
Lukas A Huber for critically reading the manuscript, Ming Li, Peter Espenshade,
Sebastien Leon, and Scott Emr for reagents, Bob Kaufmann for help in characterizing
the Dsc2 L1 loop mutant. This research was funded in part by the Austrian Science
Fund (FWF) (10.55776/P32161, 10.55776/P34907, 10.55776/DOC82 to DT, and 10.55776/P36187
to OS), by a Lipotype lipidomics excellence award (LEA 2019) to OS, by a Luxembourg
National Research Fund (FNR): Grant #13571826 to YW, and by European Union’s Horizon
2020 research and innovation program under the Marie Skłodowska-Curie grant agreement
No. 847681 (to KRL). For open access purposes, the author has applied a CC BY public
copyright license to any author accepted manuscript version arising from this submission.'
article_number: '9257'
article_processing_charge: Yes
article_type: original
author:
- first_name: Yannick
full_name: Weyer, Yannick
last_name: Weyer
- first_name: Sinead I.
full_name: Schwabl, Sinead I.
last_name: Schwabl
- first_name: Xuechen
full_name: Tang, Xuechen
last_name: Tang
- first_name: Astha
full_name: Purwar, Astha
last_name: Purwar
- first_name: Konstantin
full_name: Siegmann, Konstantin
last_name: Siegmann
- first_name: Angela
full_name: Ruepp, Angela
last_name: Ruepp
- first_name: Theresia
full_name: Dunzendorfer-Matt, Theresia
last_name: Dunzendorfer-Matt
- first_name: Michael A.
full_name: Widerin, Michael A.
last_name: Widerin
- first_name: Veronika
full_name: Niedrist, Veronika
last_name: Niedrist
- first_name: Noa J.M.
full_name: Mutsters, Noa J.M.
last_name: Mutsters
- first_name: Maria G.
full_name: Tettamanti, Maria G.
last_name: Tettamanti
- first_name: Sabine
full_name: Weys, Sabine
id: caffa136-9669-11ed-9092-ceac12ac9c05
last_name: Weys
- first_name: Bettina
full_name: Sarg, Bettina
last_name: Sarg
- first_name: Leopold
full_name: Kremser, Leopold
last_name: Kremser
- first_name: Klaus R.
full_name: Liedl, Klaus R.
last_name: Liedl
- first_name: Oliver
full_name: Schmidt, Oliver
last_name: Schmidt
- first_name: David
full_name: Teis, David
last_name: Teis
citation:
ama: Weyer Y, Schwabl SI, Tang X, et al. The Dsc ubiquitin ligase complex identifies
transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications.
2024;15. doi:10.1038/s41467-024-53676-6
apa: Weyer, Y., Schwabl, S. I., Tang, X., Purwar, A., Siegmann, K., Ruepp, A., …
Teis, D. (2024). The Dsc ubiquitin ligase complex identifies transmembrane degrons
to degrade orphaned proteins at the Golgi. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-024-53676-6
chicago: Weyer, Yannick, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin
Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, et al. “The Dsc Ubiquitin
Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at
the Golgi.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53676-6.
ieee: Y. Weyer et al., “The Dsc ubiquitin ligase complex identifies transmembrane
degrons to degrade orphaned proteins at the Golgi,” Nature Communications,
vol. 15. Springer Nature, 2024.
ista: Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt
T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser
L, Liedl KR, Schmidt O, Teis D. 2024. The Dsc ubiquitin ligase complex identifies
transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications.
15, 9257.
mla: Weyer, Yannick, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane
Degrons to Degrade Orphaned Proteins at the Golgi.” Nature Communications,
vol. 15, 9257, Springer Nature, 2024, doi:10.1038/s41467-024-53676-6.
short: Y. Weyer, S.I. Schwabl, X. Tang, A. Purwar, K. Siegmann, A. Ruepp, T. Dunzendorfer-Matt,
M.A. Widerin, V. Niedrist, N.J.M. Mutsters, M.G. Tettamanti, S. Weys, B. Sarg,
L. Kremser, K.R. Liedl, O. Schmidt, D. Teis, Nature Communications 15 (2024).
date_created: 2024-11-10T23:01:58Z
date_published: 2024-12-01T00:00:00Z
date_updated: 2026-03-05T11:20:12Z
day: '01'
ddc:
- '570'
doi: 10.1038/s41467-024-53676-6
external_id:
isi:
- '001345548100007'
pmid:
- '39461958'
file:
- access_level: open_access
checksum: 32c986fc3babec999c03a5c043310f40
content_type: application/pdf
creator: dernst
date_created: 2025-01-22T14:36:33Z
date_updated: 2025-01-22T14:36:33Z
file_id: '18870'
file_name: 2024_NatureComm_Weyer.pdf
file_size: 5634494
relation: main_file
success: 1
file_date_updated: 2025-01-22T14:36:33Z
fulldoi: https://doi.org/10.1038/s41467-024-53676-6
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade
orphaned proteins at the Golgi
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18523'
abstract:
- lang: eng
text: "Recent observations from the EIGER JWST program have measured for the first
time the quasar–galaxy cross-correlation function at z ≈ 6. The autocorrelation
function of faint z ≈ 6 quasars was also recently estimated. These measurements
provide key insights into the properties of quasars and galaxies at high redshift
and their relation with the host dark matter haloes. In this work, we interpret
these data building upon an empirical quasar population model that has been applied
successfully to quasar clustering and demographic measurements at z ≈ 2–4. We
use a new, large-volume N-body simulation with more than a trillion particles,
FLAMINGO-10k, to model quasars and galaxies simultaneously. We successfully reproduce
observations of z ≈ 6 quasars and galaxies (i.e. their clustering properties and
luminosity functions), and infer key quantities such as their luminosity–halo
mass relation, the mass function of their host haloes, and their duty cycle/occupation
fraction. Our key findings\r\nare (i) quasars reside on average in ≈ 1012.5 M
haloes (corresponding to ≈ 5σ fluctuations in the initial conditions of the linear
density field), but the distribution of host halo masses is quite broad; (ii)
the duty cycle of (UV-bright) quasar activity is relatively low (≈ 1 per cent);
(iii) galaxies (that are bright in [O III]) live in much smaller haloes (≈ 1010.9
M) and have a larger duty cycle (occupation fraction) of ≈ 13 per cent. Finally,
we focus on the inferred properties of quasars and present a homogeneous analysis
of their evolution with redshift. The picture that emerges reveals a strong evolution
of the host halo mass and duty cycle of quasars at z ≈ 2–6, and calls for new
investigations of the role of quasar activity across cosmic time."
acknowledgement: "We are grateful to Junya Arita and the SHELLQs team for sharing
their data on the quasar autocorrelation function and to Jan-Torge Schindler for
discussion on the QLF. We acknowledge helpful conversations with the ENIGMA group
at UC Santa Barbara and Leiden University. EP is grateful to Rob McGibbon and Victor
Forouhar Moreno for help with the simulation outputs, and to Timo Kist, Jiamu Huang,
and Vikram Khaire for comments on an early version of the manuscript. JFH and EP
acknowledge support from the European Research Council (ERC) under the European
Union’s Horizon 2020 research and innovation program (grant agreement No 885301).
This work is partly supported by funding from the European Union’s Horizon 2020
research and innovation programme under the Marie Skłodowska-Curie grant agreement
No 860744 (BiD4BESt). FW acknowledges support from NSF grant AST-2308258. This work
used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which
is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources
was granted through a Director’s Discretionary Time allocation in 2023/24, under
the auspices of the UKRI-funded\r\nDiRAC Federation Project. The equipment was funded
by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1,
and ST/S002502/1, Durham University, and STFC operations grant ST/R000832/1. DiRAC
is part of the National e-Infrastructure."
article_processing_charge: Yes
article_type: original
author:
- first_name: Elia
full_name: Pizzati, Elia
last_name: Pizzati
- first_name: Joseph F.
full_name: Hennawi, Joseph F.
last_name: Hennawi
- first_name: Joop
full_name: Schaye, Joop
last_name: Schaye
- first_name: Matthieu
full_name: Schaller, Matthieu
last_name: Schaller
- first_name: Anna Christina
full_name: Eilers, Anna Christina
last_name: Eilers
- first_name: Feige
full_name: Wang, Feige
last_name: Wang
- first_name: Carlos S.
full_name: Frenk, Carlos S.
last_name: Frenk
- first_name: Willem
full_name: Elbers, Willem
last_name: Elbers
- first_name: John C.
full_name: Helly, John C.
last_name: Helly
- first_name: Ruari
full_name: Mackenzie, Ruari
last_name: Mackenzie
- first_name: Jorryt J
full_name: Matthee, Jorryt J
id: 7439a258-f3c0-11ec-9501-9df22fe06720
last_name: Matthee
orcid: 0000-0003-2871-127X
- first_name: Rongmon
full_name: Bordoloi, Rongmon
last_name: Bordoloi
- first_name: Daichi
full_name: Kashino, Daichi
last_name: Kashino
- first_name: Rohan P.
full_name: Naidu, Rohan P.
last_name: Naidu
- first_name: Minghao
full_name: Yue, Minghao
last_name: Yue
citation:
ama: Pizzati E, Hennawi JF, Schaye J, et al. A unified model for the clustering
of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical
Society. 2024;534(4):3155-3175. doi:10.1093/mnras/stae2307
apa: Pizzati, E., Hennawi, J. F., Schaye, J., Schaller, M., Eilers, A. C., Wang,
F., … Yue, M. (2024). A unified model for the clustering of quasars and galaxies
at z ≈ 6. Monthly Notices of the Royal Astronomical Society. Oxford University
Press. https://doi.org/10.1093/mnras/stae2307
chicago: Pizzati, Elia, Joseph F. Hennawi, Joop Schaye, Matthieu Schaller, Anna
Christina Eilers, Feige Wang, Carlos S. Frenk, et al. “A Unified Model for the
Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal
Astronomical Society. Oxford University Press, 2024. https://doi.org/10.1093/mnras/stae2307.
ieee: E. Pizzati et al., “A unified model for the clustering of quasars and
galaxies at z ≈ 6,” Monthly Notices of the Royal Astronomical Society,
vol. 534, no. 4. Oxford University Press, pp. 3155–3175, 2024.
ista: Pizzati E, Hennawi JF, Schaye J, Schaller M, Eilers AC, Wang F, Frenk CS,
Elbers W, Helly JC, Mackenzie R, Matthee JJ, Bordoloi R, Kashino D, Naidu RP,
Yue M. 2024. A unified model for the clustering of quasars and galaxies at z ≈
6. Monthly Notices of the Royal Astronomical Society. 534(4), 3155–3175.
mla: Pizzati, Elia, et al. “A Unified Model for the Clustering of Quasars and Galaxies
at z ≈ 6.” Monthly Notices of the Royal Astronomical Society, vol. 534,
no. 4, Oxford University Press, 2024, pp. 3155–75, doi:10.1093/mnras/stae2307.
short: E. Pizzati, J.F. Hennawi, J. Schaye, M. Schaller, A.C. Eilers, F. Wang, C.S.
Frenk, W. Elbers, J.C. Helly, R. Mackenzie, J.J. Matthee, R. Bordoloi, D. Kashino,
R.P. Naidu, M. Yue, Monthly Notices of the Royal Astronomical Society 534 (2024)
3155–3175.
date_created: 2024-11-10T23:01:58Z
date_published: 2024-11-01T00:00:00Z
date_updated: 2025-09-08T14:40:22Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1093/mnras/stae2307
external_id:
isi:
- '001335663900008'
file:
- access_level: open_access
checksum: 9ea6285dd1d04d7a9e7b40a4c9e11edb
content_type: application/pdf
creator: dernst
date_created: 2024-11-12T07:17:26Z
date_updated: 2024-11-12T07:17:26Z
file_id: '18542'
file_name: 2024_MonthlyNRoyalAstronSoc_Pizzati.pdf
file_size: 2954312
relation: main_file
success: 1
file_date_updated: 2024-11-12T07:17:26Z
fulldoi: https://doi.org/10.1093/mnras/stae2307
has_accepted_license: '1'
intvolume: ' 534'
isi: 1
issue: '4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 3155-3175
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
eissn:
- 1365-2966
issn:
- 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A unified model for the clustering of quasars and galaxies at z ≈ 6
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 534
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18545'
abstract:
- lang: eng
text: Clinical implementation of therapeutic genome editing relies on efficient
in vivo delivery and the safety of CRISPR-Cas tools. Previously, we identified
PsCas9 as a Type II-B family enzyme capable of editing mouse liver genome upon
adenoviral delivery without detectable off-targets and reduced chromosomal translocations.
Yet, its efficacy remains insufficient with non-viral delivery, a common challenge
for many Cas9 orthologues. Here, we sought to redesign PsCas9 for in vivo editing
using lipid nanoparticles. We solve the PsCas9 ribonucleoprotein structure with
cryo-EM and characterize it biochemically, providing a basis for its rational
engineering. Screening over numerous guide RNA and protein variants lead us to
develop engineered PsCas9 (ePsCas9) with up to 20-fold increased activity across
various targets and preserved safety advantages. We apply the same design principles
to boost the activity of FnCas9, an enzyme phylogenetically relevant to PsCas9.
Remarkably, a single administration of mRNA encoding ePsCas9 and its guide formulated
with lipid nanoparticles results in high levels of editing in the Pcsk9 gene in
mouse liver, a clinically relevant target for hypercholesterolemia treatment.
Collectively, our findings introduce ePsCas9 as a highly efficient, and precise
tool for therapeutic genome editing, in addition to the engineering strategy applicable
to other Cas9 orthologues.
article_number: '9173'
article_processing_charge: Yes
article_type: original
author:
- first_name: Dmitrii
full_name: Degtev, Dmitrii
last_name: Degtev
- first_name: Jack Peter Kelly
full_name: Bravo, Jack Peter Kelly
id: 96aecfa5-8931-11ee-af30-aa6a5d6eee0e
last_name: Bravo
orcid: 0000-0003-0456-0753
- first_name: Aikaterini
full_name: Emmanouilidi, Aikaterini
last_name: Emmanouilidi
- first_name: Aleksandar
full_name: Zdravković, Aleksandar
last_name: Zdravković
- first_name: Oi Kuan
full_name: Choong, Oi Kuan
last_name: Choong
- first_name: Julia
full_name: Liz Touza, Julia
last_name: Liz Touza
- first_name: Niklas
full_name: Selfjord, Niklas
last_name: Selfjord
- first_name: Isabel
full_name: Weisheit, Isabel
last_name: Weisheit
- first_name: Margherita
full_name: Francescatto, Margherita
last_name: Francescatto
- first_name: Pinar
full_name: Akcakaya, Pinar
last_name: Akcakaya
- first_name: Michelle
full_name: Porritt, Michelle
last_name: Porritt
- first_name: Marcello
full_name: Maresca, Marcello
last_name: Maresca
- first_name: David
full_name: Taylor, David
last_name: Taylor
- first_name: Grzegorz
full_name: Sienski, Grzegorz
last_name: Sienski
citation:
ama: Degtev D, Bravo JPK, Emmanouilidi A, et al. Engineered PsCas9 enables therapeutic
genome editing in mouse liver with lipid nanoparticles. Nature Communications.
2024;15. doi:10.1038/s41467-024-53418-8
apa: Degtev, D., Bravo, J. P. K., Emmanouilidi, A., Zdravković, A., Choong, O. K.,
Liz Touza, J., … Sienski, G. (2024). Engineered PsCas9 enables therapeutic genome
editing in mouse liver with lipid nanoparticles. Nature Communications.
Springer Nature. https://doi.org/10.1038/s41467-024-53418-8
chicago: Degtev, Dmitrii, Jack Peter Kelly Bravo, Aikaterini Emmanouilidi, Aleksandar
Zdravković, Oi Kuan Choong, Julia Liz Touza, Niklas Selfjord, et al. “Engineered
PsCas9 Enables Therapeutic Genome Editing in Mouse Liver with Lipid Nanoparticles.”
Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53418-8.
ieee: D. Degtev et al., “Engineered PsCas9 enables therapeutic genome editing
in mouse liver with lipid nanoparticles,” Nature Communications, vol. 15.
Springer Nature, 2024.
ista: Degtev D, Bravo JPK, Emmanouilidi A, Zdravković A, Choong OK, Liz Touza J,
Selfjord N, Weisheit I, Francescatto M, Akcakaya P, Porritt M, Maresca M, Taylor
D, Sienski G. 2024. Engineered PsCas9 enables therapeutic genome editing in mouse
liver with lipid nanoparticles. Nature Communications. 15, 9173.
mla: Degtev, Dmitrii, et al. “Engineered PsCas9 Enables Therapeutic Genome Editing
in Mouse Liver with Lipid Nanoparticles.” Nature Communications, vol. 15,
9173, Springer Nature, 2024, doi:10.1038/s41467-024-53418-8.
short: D. Degtev, J.P.K. Bravo, A. Emmanouilidi, A. Zdravković, O.K. Choong, J.
Liz Touza, N. Selfjord, I. Weisheit, M. Francescatto, P. Akcakaya, M. Porritt,
M. Maresca, D. Taylor, G. Sienski, Nature Communications 15 (2024).
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abstract:
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text: We prove the Eigenstate Thermalization Hypothesis for general Wigner-type
matrices in the bulk of the self-consistent spectrum, with optimal control on
the fluctuations for obs ervables of arbitrary rank. As the main technical ingredient,
we prove rank-uniform optimal local laws for one and two resolvents of a Wigner-type
matrix with regular observables. Our results hold under very general conditions
on the variance profile, even allowing many vanishing entries, demonstrating that
Eigenstate Thermalization occurs robustly across a diverse class of random matrix
ensembles, for which the underlying quantum system has a non-trivial spatial structure.
acknowledgement: Open access funding provided by Institute of Science and Technology
(IST Austria).
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author:
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full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
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full_name: Riabov, Volodymyr
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ama: Erdös L, Riabov V. Eigenstate Thermalization Hypothesis for Wigner-type matrices.
Communications in Mathematical Physics. 2024;405(12). doi:10.1007/s00220-024-05143-y
apa: Erdös, L., & Riabov, V. (2024). Eigenstate Thermalization Hypothesis for
Wigner-type matrices. Communications in Mathematical Physics. Springer
Nature. https://doi.org/10.1007/s00220-024-05143-y
chicago: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis
for Wigner-Type Matrices.” Communications in Mathematical Physics. Springer
Nature, 2024. https://doi.org/10.1007/s00220-024-05143-y.
ieee: L. Erdös and V. Riabov, “Eigenstate Thermalization Hypothesis for Wigner-type
matrices,” Communications in Mathematical Physics, vol. 405, no. 12. Springer
Nature, 2024.
ista: Erdös L, Riabov V. 2024. Eigenstate Thermalization Hypothesis for Wigner-type
matrices. Communications in Mathematical Physics. 405(12), 282.
mla: Erdös, László, and Volodymyr Riabov. “Eigenstate Thermalization Hypothesis
for Wigner-Type Matrices.” Communications in Mathematical Physics, vol.
405, no. 12, 282, Springer Nature, 2024, doi:10.1007/s00220-024-05143-y.
short: L. Erdös, V. Riabov, Communications in Mathematical Physics 405 (2024).
corr_author: '1'
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title: Eigenstate Thermalization Hypothesis for Wigner-type matrices
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