---
APC_amount: 3145,39 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '17890'
abstract:
- lang: eng
  text: Our understanding of the molecular pathways that regulate oogenesis and define
    cellular identity in the Arthropod female reproductive system and the extent of
    their conservation is currently very limited. This is due to the focus on model
    systems, including Drosophila and Daphnia, which do not reflect the observed diversity
    of morphologies, reproductive modes, and sex chromosome systems. We use single-nucleus
    RNA and ATAC sequencing to produce a comprehensive single nucleus atlas of the
    adult Artemia franciscana female reproductive system. We map our data to the Fly
    Cell Atlas single-nucleus dataset of the Drosophila melanogaster ovary, shedding
    light on the conserved regulatory programs between the two distantly related Arthropod
    species. We identify the major cell types known to be present in the Artemia ovary,
    including germ cells, follicle cells, and ovarian muscle cells. Additionally,
    we use the germ cells to explore gene regulation and expression of the Z chromosome
    during meiosis, highlighting its unique regulatory dynamics and allowing us to
    explore the presence of meiotic sex chromosome silencing in this group.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank the Vicoso group for their valuable comments on the earlier
  draft of the manuscript. We would also like to thank the Vienna BioCenter Next Generation
  Sequencing (NGS) facility staff, and in particular, Thomas Grentzinger for his support
  with the handling and sequencing of the samples, the scientific computing unit at
  ISTA for the computational resources, Brittney Wick for the help with hosting our
  data on the UCSC Cell Browser, and Lora B. Sweeney for her valuable input at the
  different stages of the project.\r\nThis research was funded by the Austrian science
  fund (FWF), as part of the SFB Meiosis consortium https://sfbmeiosis.org/, grant
  ID FWF SFB F88-10) to BV. "
article_number: e1011376
article_processing_charge: Yes
article_type: original
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Elkrewi MN, Vicoso B. Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome. <i>PLoS Genetics</i>.
    2024;20(8). doi:<a href="https://doi.org/10.1371/journal.pgen.1011376">10.1371/journal.pgen.1011376</a>
  apa: Elkrewi, M. N., &#38; Vicoso, B. (2024). Single-nucleus atlas of the Artemia
    female reproductive system suggests germline repression of the Z chromosome. <i>PLoS
    Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1011376">https://doi.org/10.1371/journal.pgen.1011376</a>
  chicago: Elkrewi, Marwan N, and Beatriz Vicoso. “Single-Nucleus Atlas of the Artemia
    Female Reproductive System Suggests Germline Repression of the Z Chromosome.”
    <i>PLoS Genetics</i>. Public Library of Science, 2024. <a href="https://doi.org/10.1371/journal.pgen.1011376">https://doi.org/10.1371/journal.pgen.1011376</a>.
  ieee: M. N. Elkrewi and B. Vicoso, “Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome,” <i>PLoS Genetics</i>,
    vol. 20, no. 8. Public Library of Science, 2024.
  ista: Elkrewi MN, Vicoso B. 2024. Single-nucleus atlas of the Artemia female reproductive
    system suggests germline repression of the Z chromosome. PLoS Genetics. 20(8),
    e1011376.
  mla: Elkrewi, Marwan N., and Beatriz Vicoso. “Single-Nucleus Atlas of the Artemia
    Female Reproductive System Suggests Germline Repression of the Z Chromosome.”
    <i>PLoS Genetics</i>, vol. 20, no. 8, e1011376, Public Library of Science, 2024,
    doi:<a href="https://doi.org/10.1371/journal.pgen.1011376">10.1371/journal.pgen.1011376</a>.
  short: M.N. Elkrewi, B. Vicoso, PLoS Genetics 20 (2024).
corr_author: '1'
date_created: 2024-09-08T22:01:11Z
date_published: 2024-08-30T00:00:00Z
date_updated: 2026-05-27T22:31:20Z
day: '30'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1371/journal.pgen.1011376
external_id:
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file:
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intvolume: '        20'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/Melkrewi/Artemia-snRNAseq-Project
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status: public
title: Single-nucleus atlas of the Artemia female reproductive system suggests germline
  repression of the Z chromosome
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 20
year: '2024'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '15009'
abstract:
- lang: eng
  text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
    this lineage, and in particular the model species Artemia franciscana, has been
    the subject of extensive research. However, our understanding of the genetic mechanisms
    underlying various aspects of their reproductive biology, including sex determination,
    is still lacking. This is partly due to the scarcity of genomic resources for
    Artemia species and crustaceans in general. Here, we present a chromosome-level
    genome assembly of A. franciscana (Kellogg 1906), from the Great Salt Lake, United
    States. The genome is 1 GB, and the majority of the genome (81%) is scaffolded
    into 21 linkage groups using a previously published high-density linkage map.
    We performed coverage and FST analyses using male and female genomic and transcriptomic
    reads to quantify the extent of differentiation between the Z and W chromosomes.
    Additionally, we quantified the expression levels in male and female heads and
    gonads and found further evidence for dosage compensation in this species.
article_number: evae006
article_processing_charge: Yes
article_type: original
author:
- first_name: Vincent K
  full_name: Bett, Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- first_name: Ariana
  full_name: Macon, Ariana
  id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
  last_name: Macon
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
citation:
  ama: Bett VK, Macon A, Vicoso B, Elkrewi MN. Chromosome-level assembly of Artemia
    franciscana sheds light on sex chromosome differentiation. <i>Genome Biology and
    Evolution</i>. 2024;16(1). doi:<a href="https://doi.org/10.1093/gbe/evae006">10.1093/gbe/evae006</a>
  apa: Bett, V. K., Macon, A., Vicoso, B., &#38; Elkrewi, M. N. (2024). Chromosome-level
    assembly of Artemia franciscana sheds light on sex chromosome differentiation.
    <i>Genome Biology and Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/gbe/evae006">https://doi.org/10.1093/gbe/evae006</a>
  chicago: Bett, Vincent K, Ariana Macon, Beatriz Vicoso, and Marwan N Elkrewi. “Chromosome-Level
    Assembly of Artemia Franciscana Sheds Light on Sex Chromosome Differentiation.”
    <i>Genome Biology and Evolution</i>. Oxford University Press, 2024. <a href="https://doi.org/10.1093/gbe/evae006">https://doi.org/10.1093/gbe/evae006</a>.
  ieee: V. K. Bett, A. Macon, B. Vicoso, and M. N. Elkrewi, “Chromosome-level assembly
    of Artemia franciscana sheds light on sex chromosome differentiation,” <i>Genome
    Biology and Evolution</i>, vol. 16, no. 1. Oxford University Press, 2024.
  ista: Bett VK, Macon A, Vicoso B, Elkrewi MN. 2024. Chromosome-level assembly of
    Artemia franciscana sheds light on sex chromosome differentiation. Genome Biology
    and Evolution. 16(1), evae006.
  mla: Bett, Vincent K., et al. “Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex Chromosome Differentiation.” <i>Genome Biology and Evolution</i>,
    vol. 16, no. 1, evae006, Oxford University Press, 2024, doi:<a href="https://doi.org/10.1093/gbe/evae006">10.1093/gbe/evae006</a>.
  short: V.K. Bett, A. Macon, B. Vicoso, M.N. Elkrewi, Genome Biology and Evolution
    16 (2024).
corr_author: '1'
date_created: 2024-02-18T23:01:02Z
date_published: 2024-01-20T00:00:00Z
date_updated: 2026-05-27T22:31:20Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evae006
external_id:
  isi:
  - '001153952800001'
  pmid:
  - '38245839'
file:
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  checksum: 106a40f10443b2e7ba66749844ebbdf1
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  creator: dernst
  date_created: 2024-02-26T09:54:59Z
  date_updated: 2024-02-26T09:54:59Z
  file_id: '15029'
  file_name: 2024_GBE_Bett.pdf
  file_size: 5213306
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  success: 1
file_date_updated: 2024-02-26T09:54:59Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology and Evolution
publication_identifier:
  eissn:
  - 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  record:
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    status: public
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  - id: '19386'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Chromosome-level assembly of Artemia franciscana sheds light on sex chromosome
  differentiation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 16
year: '2024'
...
---
APC_amount: 3782,54
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '17183'
abstract:
- lang: eng
  text: "The photon blockade breakdown in a continuously driven cavity QED system
    has been proposed as a prime example for a first-order driven-dissipative quantum
    phase transition. However, the predicted scaling from a microscopic behavior—dominated
    by quantum fluctuations—to a macroscopic one—characterized by stable phases—and
    the associated exponents and phase diagram have not been observed so far. In this
    work we couple a single transmon qubit with a fixed coupling strength \U0001D454
    to a superconducting cavity that is in situ bandwidth \U0001D705 tunable to controllably
    approach this thermodynamic limit. Even though the system remains microscopic,
    we observe its behavior becoming increasingly macroscopic as a function of \U0001D454/\U0001D705.
    For the highest realized \U0001D454/\U0001D705 of approximately 287, the system
    switches with a characteristic timescale as long as 6 s between a bright coherent
    state with approximately 8×103 intracavity photons and the vacuum state. This
    exceeds the microscopic timescales by 6 orders of magnitude and approaches the
    perfect hysteresis expected between two macroscopic attractors in the thermodynamic
    limit. These findings and interpretation are qualitatively supported by neoclassical
    theory and large-scale quantum-jump Monte Carlo simulations. Besides shedding
    more light on driven-dissipative physics in the limit of strong light-matter coupling,
    this system might also find applications in quantum sensing and metrology."
acknowledged_ssus:
- _id: M-Shop
acknowledgement: This work has received funding from the Austrian Science Fund (FWF)
  through BeyondC (F7105) and the European Union’s Horizon 2020 research and innovation
  program under Grant Agreement No. 862644 (FETopen QUARTET). A.V. acknowledges support
  from the National Research, Development and Innovation Office of Hungary (NKFIH)
  within the Quantum Information National Laboratory of Hungary. The authors thank
  the MIBA workshop and the Institute of Science and Technology Austria nanofabrication
  facility for technical support. We are grateful to HUN-REN Cloud for providing us
  with suitable computational infrastructure for the simulations.
article_number: '010327'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Riya
  full_name: Sett, Riya
  id: 2E6D040E-F248-11E8-B48F-1D18A9856A87
  last_name: Sett
  orcid: 0000-0001-7641-8348
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Duc T
  full_name: Phan, Duc T
  id: 29C8C0B4-F248-11E8-B48F-1D18A9856A87
  last_name: Phan
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Andras
  full_name: Vukics, Andras
  last_name: Vukics
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. Emergent macroscopic
    bistability induced by a single superconducting qubit. <i>PRX Quantum</i>. 2024;5(1).
    doi:<a href="https://doi.org/10.1103/prxquantum.5.010327">10.1103/prxquantum.5.010327</a>
  apa: Sett, R., Hassani, F., Phan, D. T., Barzanjeh, S., Vukics, A., &#38; Fink,
    J. M. (2024). Emergent macroscopic bistability induced by a single superconducting
    qubit. <i>PRX Quantum</i>. American Physical Society. <a href="https://doi.org/10.1103/prxquantum.5.010327">https://doi.org/10.1103/prxquantum.5.010327</a>
  chicago: Sett, Riya, Farid Hassani, Duc T Phan, Shabir Barzanjeh, Andras Vukics,
    and Johannes M Fink. “Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit.” <i>PRX Quantum</i>. American Physical Society, 2024. <a href="https://doi.org/10.1103/prxquantum.5.010327">https://doi.org/10.1103/prxquantum.5.010327</a>.
  ieee: R. Sett, F. Hassani, D. T. Phan, S. Barzanjeh, A. Vukics, and J. M. Fink,
    “Emergent macroscopic bistability induced by a single superconducting qubit,”
    <i>PRX Quantum</i>, vol. 5, no. 1. American Physical Society, 2024.
  ista: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. 2024. Emergent
    macroscopic bistability induced by a single superconducting qubit. PRX Quantum.
    5(1), 010327.
  mla: Sett, Riya, et al. “Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit.” <i>PRX Quantum</i>, vol. 5, no. 1, 010327, American Physical Society,
    2024, doi:<a href="https://doi.org/10.1103/prxquantum.5.010327">10.1103/prxquantum.5.010327</a>.
  short: R. Sett, F. Hassani, D.T. Phan, S. Barzanjeh, A. Vukics, J.M. Fink, PRX Quantum
    5 (2024).
corr_author: '1'
date_created: 2024-06-27T10:58:06Z
date_published: 2024-02-16T00:00:00Z
date_updated: 2026-05-27T22:31:23Z
day: '16'
ddc:
- '530'
department:
- _id: JoFi
- _id: AnHi
doi: 10.1103/prxquantum.5.010327
ec_funded: 1
external_id:
  arxiv:
  - '2210.14182'
  isi:
  - '001171652500001'
file:
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  creator: cchlebak
  date_created: 2024-06-28T12:04:43Z
  date_updated: 2024-06-28T12:04:43Z
  file_id: '17185'
  file_name: 2024_PRXQuantum_Sett.pdf
  file_size: 1443351
  relation: main_file
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file_date_updated: 2024-06-28T12:04:43Z
has_accepted_license: '1'
intvolume: '         5'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862644'
  name: Quantum readout techniques and technologies
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
  grant_number: F07105
  name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
    of Superconducting Quantum Circuits
publication: PRX Quantum
publication_identifier:
  eissn:
  - 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
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  - id: '19533'
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scopus_import: '1'
status: public
title: Emergent macroscopic bistability induced by a single superconducting qubit
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '14796'
abstract:
- lang: eng
  text: Key innovations are fundamental to biological diversification, but their genetic
    basis is poorly understood. A recent transition from egg-laying to live-bearing
    in marine snails (Littorina spp.) provides the opportunity to study the genetic
    architecture of an innovation that has evolved repeatedly across animals. Individuals
    do not cluster by reproductive mode in a genome-wide phylogeny, but local genealogical
    analysis revealed numerous small genomic regions where all live-bearers carry
    the same core haplotype. Candidate regions show evidence for live-bearer–specific
    positive selection and are enriched for genes that are differentially expressed
    between egg-laying and live-bearing reproductive systems. Ages of selective sweeps
    suggest that live-bearer–specific alleles accumulated over more than 200,000 generations.
    Our results suggest that new functions evolve through the recruitment of many
    alleles rather than in a single evolutionary step.
acknowledgement: "We thank J. Galindo, M. Montaño-Rendón, N. Mikhailova, A. Blakeslee,
  E. Arnason, and P. Kemppainen for providing samples; R. Turney, G. Sotelo, J. Larsson,
  T. Broquet, and S. Loisel for help collecting samples; Science Animated for providing
  the snail cartoons shown in Fig. 1; M. Dunning for help in developing bioinformatic
  pipelines; R. Faria, H. Morales, and V. Sousa for advice; and M. Hahn, J. Slate,
  M. Ravinet, J. Raeymaekers, A. Comeault, and N. Barton for feedback on a draft manuscript.\r\nThis
  work was supported by the Natural Environment Research Council (grant NE/P001610/1
  to R.K.B.), the European Research Council (grant ERC-2015-AdG693030-BARRIERS to
  R.K.B.), the Norwegian Research Council (RCN Project 315287 to A.M.W.), and the
  Swedish Research Council (grant 2020-05385 to E.L.)."
article_processing_charge: No
article_type: original
author:
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Zuzanna B.
  full_name: Zagrodzka, Zuzanna B.
  last_name: Zagrodzka
- first_name: Martin D.
  full_name: Garlovsky, Martin D.
  last_name: Garlovsky
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
  orcid: 0000-0002-4530-8469
- first_name: Daria
  full_name: Shipilina, Daria
  id: 428A94B0-F248-11E8-B48F-1D18A9856A87
  last_name: Shipilina
  orcid: 0000-0002-1145-9226
- first_name: Diego Fernando
  full_name: Garcia Castillo, Diego Fernando
  id: ae681a14-dc74-11ea-a0a7-c6ef18161701
  last_name: Garcia Castillo
- first_name: Hila
  full_name: Lifchitz, Hila
  id: d6ab5470-2fb3-11ed-8633-986a9b84edac
  last_name: Lifchitz
- first_name: Alan
  full_name: Le Moan, Alan
  last_name: Le Moan
- first_name: Erica
  full_name: Leder, Erica
  last_name: Leder
- first_name: James
  full_name: Reeve, James
  last_name: Reeve
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: Stankowski S, Zagrodzka ZB, Garlovsky MD, et al. The genetic basis of a recent
    transition to live-bearing in marine snails. <i>Science</i>. 2024;383(6678):114-119.
    doi:<a href="https://doi.org/10.1126/science.adi2982">10.1126/science.adi2982</a>
  apa: Stankowski, S., Zagrodzka, Z. B., Garlovsky, M. D., Pal, A., Shipilina, D.,
    Garcia Castillo, D. F., … Butlin, R. K. (2024). The genetic basis of a recent
    transition to live-bearing in marine snails. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.adi2982">https://doi.org/10.1126/science.adi2982</a>
  chicago: Stankowski, Sean, Zuzanna B. Zagrodzka, Martin D. Garlovsky, Arka Pal,
    Daria Shipilina, Diego Fernando Garcia Castillo, Hila Lifchitz, et al. “The Genetic
    Basis of a Recent Transition to Live-Bearing in Marine Snails.” <i>Science</i>.
    American Association for the Advancement of Science, 2024. <a href="https://doi.org/10.1126/science.adi2982">https://doi.org/10.1126/science.adi2982</a>.
  ieee: S. Stankowski <i>et al.</i>, “The genetic basis of a recent transition to
    live-bearing in marine snails,” <i>Science</i>, vol. 383, no. 6678. American Association
    for the Advancement of Science, pp. 114–119, 2024.
  ista: Stankowski S, Zagrodzka ZB, Garlovsky MD, Pal A, Shipilina D, Garcia Castillo
    DF, Lifchitz H, Le Moan A, Leder E, Reeve J, Johannesson K, Westram AM, Butlin
    RK. 2024. The genetic basis of a recent transition to live-bearing in marine snails.
    Science. 383(6678), 114–119.
  mla: Stankowski, Sean, et al. “The Genetic Basis of a Recent Transition to Live-Bearing
    in Marine Snails.” <i>Science</i>, vol. 383, no. 6678, American Association for
    the Advancement of Science, 2024, pp. 114–19, doi:<a href="https://doi.org/10.1126/science.adi2982">10.1126/science.adi2982</a>.
  short: S. Stankowski, Z.B. Zagrodzka, M.D. Garlovsky, A. Pal, D. Shipilina, D.F.
    Garcia Castillo, H. Lifchitz, A. Le Moan, E. Leder, J. Reeve, K. Johannesson,
    A.M. Westram, R.K. Butlin, Science 383 (2024) 114–119.
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-05T00:00:00Z
date_updated: 2026-05-27T22:31:22Z
day: '05'
department:
- _id: NiBa
- _id: GradSch
doi: 10.1126/science.adi2982
external_id:
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issue: '6678'
language:
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main_file_link:
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  url: https://figshare.com/articles/journal_contribution/The_genetic_basis_of_a_recent_transition_to_live-bearing_in_marine_snails/26356054?file=47868241
month: '01'
oa: 1
oa_version: Submitted Version
page: 114-119
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
  link:
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    relation: press_release
    url: https://ista.ac.at/en/news/the-snail-or-the-egg/
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scopus_import: '1'
status: public
title: The genetic basis of a recent transition to live-bearing in marine snails
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 383
year: '2024'
...
---
OA_place: repository
OA_type: gold
_id: '18978'
abstract:
- lang: eng
  text: "Data analysis files for the manuscript \"Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit\".\r\n\r\nThis contains the raw data
    and the data analysis files for generating the figures in the manuscript.\r\n\r\n
    Figure1 file - The raw data of cavity transmission spectra for 6 different kappas
    are there. They are fitted with input-output theory in the python file.\r\n Figure2
    file - The raw data at 8 MHz kappa are included. all hte figures in figure 2 are
    generated in the python file\r\n Figure3 file - The raw data of PBB single shot
    measurements at all kappas are included. The detailed analysis and the Figure3
    generated for the paper are all in the python analysis file. Also, thefiles containing
    the time-evolution of the intensity from Master Equation solution are included.\r\nFigure4
    file - The raw data at 2.6 MHz for different drive detunings and the corresponding
    analyses are included. And the python file includes the analysis of the experimental
    data as well as approximate neoclassical equations solutions for 2-level and 3-level
    transmons are included.  "
article_processing_charge: No
author:
- first_name: Riya
  full_name: Sett, Riya
  id: 2E6D040E-F248-11E8-B48F-1D18A9856A87
  last_name: Sett
  orcid: 0000-0001-7641-8348
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Duc T
  full_name: Phan, Duc T
  id: 29C8C0B4-F248-11E8-B48F-1D18A9856A87
  last_name: Phan
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Andras
  full_name: Vukics, Andras
  last_name: Vukics
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. Data Analysis files
    for “Emergent Macroscopic Bistability Induced by a Single Superconducting Qubit.”
    2024. doi:<a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>
  apa: Sett, R., Hassani, F., Phan, D. T., Barzanjeh, S., Vukics, A., &#38; Fink,
    J. M. (2024). Data Analysis files for “Emergent Macroscopic Bistability Induced
    by a Single Superconducting Qubit.” Zenodo. <a href="https://doi.org/10.5281/ZENODO.10518320">https://doi.org/10.5281/ZENODO.10518320</a>
  chicago: Sett, Riya, Farid Hassani, Duc T Phan, Shabir Barzanjeh, Andras Vukics,
    and Johannes M Fink. “Data Analysis Files for ‘Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit.’” Zenodo, 2024. <a href="https://doi.org/10.5281/ZENODO.10518320">https://doi.org/10.5281/ZENODO.10518320</a>.
  ieee: R. Sett, F. Hassani, D. T. Phan, S. Barzanjeh, A. Vukics, and J. M. Fink,
    “Data Analysis files for ‘Emergent Macroscopic Bistability Induced by a Single
    Superconducting Qubit.’” Zenodo, 2024.
  ista: Sett R, Hassani F, Phan DT, Barzanjeh S, Vukics A, Fink JM. 2024. Data Analysis
    files for ‘Emergent Macroscopic Bistability Induced by a Single Superconducting
    Qubit’, Zenodo, <a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>.
  mla: Sett, Riya, et al. <i>Data Analysis Files for “Emergent Macroscopic Bistability
    Induced by a Single Superconducting Qubit.”</i> Zenodo, 2024, doi:<a href="https://doi.org/10.5281/ZENODO.10518320">10.5281/ZENODO.10518320</a>.
  short: R. Sett, F. Hassani, D.T. Phan, S. Barzanjeh, A. Vukics, J.M. Fink, (2024).
corr_author: '1'
date_created: 2025-01-30T08:30:03Z
date_published: 2024-01-16T00:00:00Z
date_updated: 2026-05-27T22:31:23Z
day: '16'
ddc:
- '530'
department:
- _id: JoFi
- _id: AnHi
doi: 10.5281/ZENODO.10518320
has_accepted_license: '1'
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.10518320
month: '01'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '17183'
    relation: used_in_publication
    status: public
  - id: '19533'
    relation: used_in_publication
    status: public
status: public
title: Data Analysis files for "Emergent Macroscopic Bistability Induced by a Single
  Superconducting Qubit"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '11479'
abstract:
- lang: eng
  text: Understanding population divergence that eventually leads to speciation is
    essential for evolutionary biology. High species diversity in the sea was regarded
    as a paradox when strict allopatry was considered necessary for most speciation
    events because geographical barriers seemed largely absent in the sea, and many
    marine species have high dispersal capacities. Combining genome-wide data with
    demographic modelling to infer the demographic history of divergence has introduced
    new ways to address this classical issue. These models assume an ancestral population
    that splits into two subpopulations diverging according to different scenarios
    that allow tests for periods of gene flow. Models can also test for heterogeneities
    in population sizes and migration rates along the genome to account, respectively,
    for background selection and selection against introgressed ancestry. To investigate
    how barriers to gene flow arise in the sea, we compiled studies modelling the
    demographic history of divergence in marine organisms and extracted preferred
    demographic scenarios together with estimates of demographic parameters. These
    studies show that geographical barriers to gene flow do exist in the sea but that
    divergence can also occur without strict isolation. Heterogeneity of gene flow
    was detected in most population pairs suggesting the predominance of semipermeable
    barriers during divergence. We found a weak positive relationship between the
    fraction of the genome experiencing reduced gene flow and levels of genome-wide
    differentiation. Furthermore, we found that the upper bound of the ‘grey zone
    of speciation’ for our dataset extended beyond that found before, implying that
    gene flow between diverging taxa is possible at higher levels of divergence than
    previously thought. Finally, we list recommendations for further strengthening
    the use of demographic modelling in speciation research. These include a more
    balanced representation of taxa, more consistent and comprehensive modelling,
    clear reporting of results and simulation studies to rule out nonbiological explanations
    for general results.
acknowledgement: 'We greatly thank all the corresponding authors of the studies that
  were included in our synthesis for the sharing of additional data: Thomas Broquet,
  Dmitry Filatov, Quentin Rougemont, Paolo Momigliano, Pierre-Alexandre Gagnaire,
  Carlos Prada, Ahmed Souissi, Michael Møller Hansen, Sylvie Lapègue, Joseph Di Battista,
  Michael Hellberg and Carlos Prada. RKB and ADJ were supported by the European Research
  Council. MR was supported by the Swedish Research Council Vetenskapsrådet (grant
  number 2021-05243; to MR) and Formas (grant number 2019-00882; to KJ and MR), and
  by additional grants from the European Research Council (to RKB) and Vetenskapsrådet
  (to KJ) through the Centre for Marine Evolutionary Biology (https://www.gu.se/en/cemeb-marine-evolutionary-biology).'
article_processing_charge: No
article_type: original
author:
- first_name: Aurélien
  full_name: De Jode, Aurélien
  last_name: De Jode
- first_name: Alan
  full_name: Le Moan, Alan
  last_name: Le Moan
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
citation:
  ama: De Jode A, Le Moan A, Johannesson K, et al. Ten years of demographic modelling
    of divergence and speciation in the sea. <i>Evolutionary Applications</i>. 2023;16(2):542-559.
    doi:<a href="https://doi.org/10.1111/eva.13428">10.1111/eva.13428</a>
  apa: De Jode, A., Le Moan, A., Johannesson, K., Faria, R., Stankowski, S., Westram,
    A. M., … Fraisse, C. (2023). Ten years of demographic modelling of divergence
    and speciation in the sea. <i>Evolutionary Applications</i>. Wiley. <a href="https://doi.org/10.1111/eva.13428">https://doi.org/10.1111/eva.13428</a>
  chicago: De Jode, Aurélien, Alan Le Moan, Kerstin Johannesson, Rui Faria, Sean Stankowski,
    Anja M Westram, Roger K. Butlin, Marina Rafajlović, and Christelle Fraisse. “Ten
    Years of Demographic Modelling of Divergence and Speciation in the Sea.” <i>Evolutionary
    Applications</i>. Wiley, 2023. <a href="https://doi.org/10.1111/eva.13428">https://doi.org/10.1111/eva.13428</a>.
  ieee: A. De Jode <i>et al.</i>, “Ten years of demographic modelling of divergence
    and speciation in the sea,” <i>Evolutionary Applications</i>, vol. 16, no. 2.
    Wiley, pp. 542–559, 2023.
  ista: De Jode A, Le Moan A, Johannesson K, Faria R, Stankowski S, Westram AM, Butlin
    RK, Rafajlović M, Fraisse C. 2023. Ten years of demographic modelling of divergence
    and speciation in the sea. Evolutionary Applications. 16(2), 542–559.
  mla: De Jode, Aurélien, et al. “Ten Years of Demographic Modelling of Divergence
    and Speciation in the Sea.” <i>Evolutionary Applications</i>, vol. 16, no. 2,
    Wiley, 2023, pp. 542–59, doi:<a href="https://doi.org/10.1111/eva.13428">10.1111/eva.13428</a>.
  short: A. De Jode, A. Le Moan, K. Johannesson, R. Faria, S. Stankowski, A.M. Westram,
    R.K. Butlin, M. Rafajlović, C. Fraisse, Evolutionary Applications 16 (2023) 542–559.
date_created: 2022-07-03T22:01:33Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2025-04-23T08:49:14Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
- _id: BeVi
doi: 10.1111/eva.13428
external_id:
  isi:
  - '000815663700001'
  pmid:
  - '36793688'
file:
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  creator: dernst
  date_created: 2023-02-27T07:10:17Z
  date_updated: 2023-02-27T07:10:17Z
  file_id: '12685'
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  file_size: 2269822
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intvolume: '        16'
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- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 542-559
pmid: 1
publication: Evolutionary Applications
publication_identifier:
  eissn:
  - 1752-4571
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ten years of demographic modelling of divergence and speciation in the sea
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2023'
...
---
_id: '11706'
abstract:
- lang: eng
  text: 'We say that (Formula presented.) if, in every edge coloring (Formula presented.),
    we can find either a 1-colored copy of (Formula presented.) or a 2-colored copy
    of (Formula presented.). The well-known states that the threshold for the property
    (Formula presented.) is equal to (Formula presented.), where (Formula presented.)
    is given by (Formula presented.) for any pair of graphs (Formula presented.) and
    (Formula presented.) with (Formula presented.). In this article, we show the 0-statement
    of the Kohayakawa–Kreuter conjecture for every pair of cycles and cliques. '
acknowledgement: "This work was started at the thematic program GRAPHS@IMPA (January–March
  2018), in Rio de Janeiro. We thank IMPA and the organisers for the hospitality and
  for providing a pleasant research environment. We thank Rob Morris for helpful discussions,
  and the anonymous referees for their careful reading and many helpful suggestions.
  Open Access funding enabled and organized by Projekt DEAL.\r\nA. Liebenau was supported
  by an ARC DECRA Fellowship Grant DE170100789. L. Mattos was supported by CAPES and
  by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's
  Excellence Strategy – The Berlin Mathematics Research Center MATH+ (EXC-2046/1,
  project ID: 390685689). W. Mendonça was supported by CAPES project 88882.332408/2010-01."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Anita
  full_name: Liebenau, Anita
  last_name: Liebenau
- first_name: Letícia
  full_name: Mattos, Letícia
  last_name: Mattos
- first_name: Walner
  full_name: Mendonca Dos Santos, Walner
  id: 12c6bd4d-2cd0-11ec-a0da-e28f42f65ebd
  last_name: Mendonca Dos Santos
- first_name: Jozef
  full_name: Skokan, Jozef
  last_name: Skokan
citation:
  ama: Liebenau A, Mattos L, Mendonca dos Santos W, Skokan J. Asymmetric Ramsey properties
    of random graphs involving cliques and cycles. <i>Random Structures and Algorithms</i>.
    2023;62(4):1035-1055. doi:<a href="https://doi.org/10.1002/rsa.21106">10.1002/rsa.21106</a>
  apa: Liebenau, A., Mattos, L., Mendonca dos Santos, W., &#38; Skokan, J. (2023).
    Asymmetric Ramsey properties of random graphs involving cliques and cycles. <i>Random
    Structures and Algorithms</i>. Wiley. <a href="https://doi.org/10.1002/rsa.21106">https://doi.org/10.1002/rsa.21106</a>
  chicago: Liebenau, Anita, Letícia Mattos, Walner Mendonca dos Santos, and Jozef
    Skokan. “Asymmetric Ramsey Properties of Random Graphs Involving Cliques and Cycles.”
    <i>Random Structures and Algorithms</i>. Wiley, 2023. <a href="https://doi.org/10.1002/rsa.21106">https://doi.org/10.1002/rsa.21106</a>.
  ieee: A. Liebenau, L. Mattos, W. Mendonca dos Santos, and J. Skokan, “Asymmetric
    Ramsey properties of random graphs involving cliques and cycles,” <i>Random Structures
    and Algorithms</i>, vol. 62, no. 4. Wiley, pp. 1035–1055, 2023.
  ista: Liebenau A, Mattos L, Mendonca dos Santos W, Skokan J. 2023. Asymmetric Ramsey
    properties of random graphs involving cliques and cycles. Random Structures and
    Algorithms. 62(4), 1035–1055.
  mla: Liebenau, Anita, et al. “Asymmetric Ramsey Properties of Random Graphs Involving
    Cliques and Cycles.” <i>Random Structures and Algorithms</i>, vol. 62, no. 4,
    Wiley, 2023, pp. 1035–55, doi:<a href="https://doi.org/10.1002/rsa.21106">10.1002/rsa.21106</a>.
  short: A. Liebenau, L. Mattos, W. Mendonca dos Santos, J. Skokan, Random Structures
    and Algorithms 62 (2023) 1035–1055.
date_created: 2022-07-31T22:01:49Z
date_published: 2023-07-01T00:00:00Z
date_updated: 2023-10-04T09:38:45Z
day: '01'
ddc:
- '510'
department:
- _id: MaKw
doi: 10.1002/rsa.21106
external_id:
  isi:
  - '000828530400001'
file:
- access_level: open_access
  checksum: 3a5969d0c512aef01c30f3dc81c6d59b
  content_type: application/pdf
  creator: dernst
  date_created: 2023-10-04T09:37:26Z
  date_updated: 2023-10-04T09:37:26Z
  file_id: '14389'
  file_name: 2023_RandomStructureAlgorithms_Liebenau.pdf
  file_size: 1362334
  relation: main_file
  success: 1
file_date_updated: 2023-10-04T09:37:26Z
has_accepted_license: '1'
intvolume: '        62'
isi: 1
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1035-1055
publication: Random Structures and Algorithms
publication_identifier:
  eissn:
  - 1098-2418
  issn:
  - 1042-9832
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Asymmetric Ramsey properties of random graphs involving cliques and cycles
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 62
year: '2023'
...
---
_id: '11741'
abstract:
- lang: eng
  text: Following E. Wigner’s original vision, we prove that sampling the eigenvalue
    gaps within the bulk spectrum of a fixed (deformed) Wigner matrix H yields the
    celebrated Wigner-Dyson-Mehta universal statistics with high probability. Similarly,
    we prove universality for a monoparametric family of deformed Wigner matrices
    H+xA with a deterministic Hermitian matrix A and a fixed Wigner matrix H, just
    using the randomness of a single scalar real random variable x. Both results constitute
    quenched versions of bulk universality that has so far only been proven in annealed
    sense with respect to the probability space of the matrix ensemble.
acknowledgement: "The authors are indebted to Sourav Chatterjee for forwarding the
  very inspiring question that Stephen Shenker originally addressed to him which initiated
  the current paper. They are also grateful that the authors of [23] kindly shared
  their preliminary numerical results in June 2021.\r\nOpen access funding provided
  by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. Quenched universality for deformed Wigner
    matrices. <i>Probability Theory and Related Fields</i>. 2023;185:1183–1218. doi:<a
    href="https://doi.org/10.1007/s00440-022-01156-7">10.1007/s00440-022-01156-7</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2023). Quenched universality
    for deformed Wigner matrices. <i>Probability Theory and Related Fields</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00440-022-01156-7">https://doi.org/10.1007/s00440-022-01156-7</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Quenched Universality
    for Deformed Wigner Matrices.” <i>Probability Theory and Related Fields</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1007/s00440-022-01156-7">https://doi.org/10.1007/s00440-022-01156-7</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Quenched universality for deformed
    Wigner matrices,” <i>Probability Theory and Related Fields</i>, vol. 185. Springer
    Nature, pp. 1183–1218, 2023.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2023. Quenched universality for deformed
    Wigner matrices. Probability Theory and Related Fields. 185, 1183–1218.
  mla: Cipolloni, Giorgio, et al. “Quenched Universality for Deformed Wigner Matrices.”
    <i>Probability Theory and Related Fields</i>, vol. 185, Springer Nature, 2023,
    pp. 1183–1218, doi:<a href="https://doi.org/10.1007/s00440-022-01156-7">10.1007/s00440-022-01156-7</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields
    185 (2023) 1183–1218.
corr_author: '1'
date_created: 2022-08-07T22:02:00Z
date_published: 2023-04-01T00:00:00Z
date_updated: 2024-10-09T21:03:02Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00440-022-01156-7
external_id:
  arxiv:
  - '2106.10200'
  isi:
  - '000830344500001'
file:
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page: 1183–1218
publication: Probability Theory and Related Fields
publication_identifier:
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publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quenched universality for deformed Wigner matrices
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year: '2023'
...
---
_id: '11999'
abstract:
- lang: eng
  text: 'A simple drawing D(G) of a graph G is one where each pair of edges share
    at most one point: either a common endpoint or a proper crossing. An edge e in
    the complement of G can be inserted into D(G) if there exists a simple drawing
    of G+e extending D(G). As a result of Levi’s Enlargement Lemma, if a drawing is
    rectilinear (pseudolinear), that is, the edges can be extended into an arrangement
    of lines (pseudolines), then any edge in the complement of G can be inserted.
    In contrast, we show that it is NP-complete to decide whether one edge can be
    inserted into a simple drawing. This remains true even if we assume that the drawing
    is pseudocircular, that is, the edges can be extended to an arrangement of pseudocircles.
    On the positive side, we show that, given an arrangement of pseudocircles A and
    a pseudosegment σ, it can be decided in polynomial time whether there exists a
    pseudocircle Φσ extending σ for which A∪{Φσ} is again an arrangement of pseudocircles.'
acknowledgement: 'This work was started during the 6th Austrian–Japanese–Mexican–Spanish
  Workshop on Discrete Geometry in June 2019 in Austria. We thank all the participants
  for the good atmosphere as well as discussions on the topic. Also, we thank Jan
  Kynčl for sending us remarks on a preliminary version of this work and an anonymous
  referee for further helpful comments.Alan Arroyo was funded by the Marie Skłodowska-Curie
  grant agreement No 754411. Fabian Klute was partially supported by the Netherlands
  Organisation for Scientific Research (NWO) under project no. 612.001.651 and by
  the Austrian Science Fund (FWF): J-4510. Irene Parada and Birgit Vogtenhuber were
  partially supported by the Austrian Science Fund (FWF): W1230 and within the collaborative
  DACH project Arrangements and Drawings as FWF project I 3340-N35. Irene Parada was
  also partially supported by the Independent Research Fund Denmark grant 2020-2023
  (9131-00044B) Dynamic Network Analysis and by the Margarita Salas Fellowship funded
  by the Ministry of Universities of Spain and the European Union (NextGenerationEU).
  Tilo Wiedera was supported by the German Research Foundation (DFG) grant CH 897/2-2.'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Alan M
  full_name: Arroyo Guevara, Alan M
  id: 3207FDC6-F248-11E8-B48F-1D18A9856A87
  last_name: Arroyo Guevara
  orcid: 0000-0003-2401-8670
- first_name: Fabian
  full_name: Klute, Fabian
  last_name: Klute
- first_name: Irene
  full_name: Parada, Irene
  last_name: Parada
- first_name: Birgit
  full_name: Vogtenhuber, Birgit
  last_name: Vogtenhuber
- first_name: Raimund
  full_name: Seidel, Raimund
  last_name: Seidel
- first_name: Tilo
  full_name: Wiedera, Tilo
  last_name: Wiedera
citation:
  ama: Arroyo Guevara AM, Klute F, Parada I, Vogtenhuber B, Seidel R, Wiedera T. Inserting
    one edge into a simple drawing is hard. <i>Discrete and Computational Geometry</i>.
    2023;69:745–770. doi:<a href="https://doi.org/10.1007/s00454-022-00394-9">10.1007/s00454-022-00394-9</a>
  apa: Arroyo Guevara, A. M., Klute, F., Parada, I., Vogtenhuber, B., Seidel, R.,
    &#38; Wiedera, T. (2023). Inserting one edge into a simple drawing is hard. <i>Discrete
    and Computational Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s00454-022-00394-9">https://doi.org/10.1007/s00454-022-00394-9</a>
  chicago: Arroyo Guevara, Alan M, Fabian Klute, Irene Parada, Birgit Vogtenhuber,
    Raimund Seidel, and Tilo Wiedera. “Inserting One Edge into a Simple Drawing Is
    Hard.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00454-022-00394-9">https://doi.org/10.1007/s00454-022-00394-9</a>.
  ieee: A. M. Arroyo Guevara, F. Klute, I. Parada, B. Vogtenhuber, R. Seidel, and
    T. Wiedera, “Inserting one edge into a simple drawing is hard,” <i>Discrete and
    Computational Geometry</i>, vol. 69. Springer Nature, pp. 745–770, 2023.
  ista: Arroyo Guevara AM, Klute F, Parada I, Vogtenhuber B, Seidel R, Wiedera T.
    2023. Inserting one edge into a simple drawing is hard. Discrete and Computational
    Geometry. 69, 745–770.
  mla: Arroyo Guevara, Alan M., et al. “Inserting One Edge into a Simple Drawing Is
    Hard.” <i>Discrete and Computational Geometry</i>, vol. 69, Springer Nature, 2023,
    pp. 745–770, doi:<a href="https://doi.org/10.1007/s00454-022-00394-9">10.1007/s00454-022-00394-9</a>.
  short: A.M. Arroyo Guevara, F. Klute, I. Parada, B. Vogtenhuber, R. Seidel, T. Wiedera,
    Discrete and Computational Geometry 69 (2023) 745–770.
date_created: 2022-08-28T22:02:01Z
date_published: 2023-04-01T00:00:00Z
date_updated: 2025-04-14T07:43:59Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1007/s00454-022-00394-9
ec_funded: 1
external_id:
  arxiv:
  - '1909.07347'
  isi:
  - '000840292800001'
file:
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oa_version: Published Version
page: 745–770
project:
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  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issn:
  - 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inserting one edge into a simple drawing is hard
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2023'
...
---
_id: '12086'
abstract:
- lang: eng
  text: We present a simple algorithm for computing higher-order Delaunay mosaics
    that works in Euclidean spaces of any finite dimensions. The algorithm selects
    the vertices of the order-k mosaic from incrementally constructed lower-order
    mosaics and uses an algorithm for weighted first-order Delaunay mosaics as a black-box
    to construct the order-k mosaic from its vertices. Beyond this black-box, the
    algorithm uses only combinatorial operations, thus facilitating easy implementation.
    We extend this algorithm to compute higher-order α-shapes and provide open-source
    implementations. We present experimental results for properties of higher-order
    Delaunay mosaics of random point sets.
acknowledgement: Open access funding provided by Austrian Science Fund (FWF). This
  project has received funding from the European Research Council (ERC) under the
  European Union’s Horizon 2020 research and innovation programme, Grant No. 788183,
  from the Wittgenstein Prize, Austrian Science Fund (FWF), Grant No. Z 342-N31, and
  from the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry
  and Dynamics’, Austrian Science Fund (FWF), Grant No. I 02979-N35.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Georg F
  full_name: Osang, Georg F
  id: 464B40D6-F248-11E8-B48F-1D18A9856A87
  last_name: Osang
  orcid: 0000-0002-8882-5116
citation:
  ama: Edelsbrunner H, Osang GF. A simple algorithm for higher-order Delaunay mosaics
    and alpha shapes. <i>Algorithmica</i>. 2023;85:277-295. doi:<a href="https://doi.org/10.1007/s00453-022-01027-6">10.1007/s00453-022-01027-6</a>
  apa: Edelsbrunner, H., &#38; Osang, G. F. (2023). A simple algorithm for higher-order
    Delaunay mosaics and alpha shapes. <i>Algorithmica</i>. Springer Nature. <a href="https://doi.org/10.1007/s00453-022-01027-6">https://doi.org/10.1007/s00453-022-01027-6</a>
  chicago: Edelsbrunner, Herbert, and Georg F Osang. “A Simple Algorithm for Higher-Order
    Delaunay Mosaics and Alpha Shapes.” <i>Algorithmica</i>. Springer Nature, 2023.
    <a href="https://doi.org/10.1007/s00453-022-01027-6">https://doi.org/10.1007/s00453-022-01027-6</a>.
  ieee: H. Edelsbrunner and G. F. Osang, “A simple algorithm for higher-order Delaunay
    mosaics and alpha shapes,” <i>Algorithmica</i>, vol. 85. Springer Nature, pp.
    277–295, 2023.
  ista: Edelsbrunner H, Osang GF. 2023. A simple algorithm for higher-order Delaunay
    mosaics and alpha shapes. Algorithmica. 85, 277–295.
  mla: Edelsbrunner, Herbert, and Georg F. Osang. “A Simple Algorithm for Higher-Order
    Delaunay Mosaics and Alpha Shapes.” <i>Algorithmica</i>, vol. 85, Springer Nature,
    2023, pp. 277–95, doi:<a href="https://doi.org/10.1007/s00453-022-01027-6">10.1007/s00453-022-01027-6</a>.
  short: H. Edelsbrunner, G.F. Osang, Algorithmica 85 (2023) 277–295.
corr_author: '1'
date_created: 2022-09-11T22:01:57Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:46:48Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00453-022-01027-6
ec_funded: 1
external_id:
  isi:
  - '000846967100001'
  pmid:
  - '36687803'
file:
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has_accepted_license: '1'
intvolume: '        85'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 277-295
pmid: 1
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: Mathematics, Computer Science
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: Algorithmica
publication_identifier:
  eissn:
  - 1432-0541
  issn:
  - 0178-4617
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A simple algorithm for higher-order Delaunay mosaics and alpha shapes
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 85
year: '2023'
...
---
_id: '12087'
abstract:
- lang: eng
  text: Following up on the recent work on lower Ricci curvature bounds for quantum
    systems, we introduce two noncommutative versions of curvature-dimension bounds
    for symmetric quantum Markov semigroups over matrix algebras. Under suitable such
    curvature-dimension conditions, we prove a family of dimension-dependent functional
    inequalities, a version of the Bonnet–Myers theorem and concavity of entropy power
    in the noncommutative setting. We also provide examples satisfying certain curvature-dimension
    conditions, including Schur multipliers over matrix algebras, Herz–Schur multipliers
    over group algebras and generalized depolarizing semigroups.
acknowledgement: H.Z. is supported by the European Union’s Horizon 2020 research and
  innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 754411
  and the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337. M.W. acknowledges
  support from the European Research Council (ERC) under the European Union’s Horizon
  2020 research and innovation programme (Grant Agreement No. 716117) and from the
  Austrian Science Fund (FWF) through grant number F65. Both authors would like to
  thank Jan Maas for fruitful discussions and helpful comments. Open access funding
  provided by Austrian Science Fund (FWF).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Melchior
  full_name: Wirth, Melchior
  id: 88644358-0A0E-11EA-8FA5-49A33DDC885E
  last_name: Wirth
  orcid: 0000-0002-0519-4241
- first_name: Haonan
  full_name: Zhang, Haonan
  id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
  last_name: Zhang
citation:
  ama: Wirth M, Zhang H. Curvature-dimension conditions for symmetric quantum Markov
    semigroups. <i>Annales Henri Poincare</i>. 2023;24:717-750. doi:<a href="https://doi.org/10.1007/s00023-022-01220-x">10.1007/s00023-022-01220-x</a>
  apa: Wirth, M., &#38; Zhang, H. (2023). Curvature-dimension conditions for symmetric
    quantum Markov semigroups. <i>Annales Henri Poincare</i>. Springer Nature. <a
    href="https://doi.org/10.1007/s00023-022-01220-x">https://doi.org/10.1007/s00023-022-01220-x</a>
  chicago: Wirth, Melchior, and Haonan Zhang. “Curvature-Dimension Conditions for
    Symmetric Quantum Markov Semigroups.” <i>Annales Henri Poincare</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1007/s00023-022-01220-x">https://doi.org/10.1007/s00023-022-01220-x</a>.
  ieee: M. Wirth and H. Zhang, “Curvature-dimension conditions for symmetric quantum
    Markov semigroups,” <i>Annales Henri Poincare</i>, vol. 24. Springer Nature, pp.
    717–750, 2023.
  ista: Wirth M, Zhang H. 2023. Curvature-dimension conditions for symmetric quantum
    Markov semigroups. Annales Henri Poincare. 24, 717–750.
  mla: Wirth, Melchior, and Haonan Zhang. “Curvature-Dimension Conditions for Symmetric
    Quantum Markov Semigroups.” <i>Annales Henri Poincare</i>, vol. 24, Springer Nature,
    2023, pp. 717–50, doi:<a href="https://doi.org/10.1007/s00023-022-01220-x">10.1007/s00023-022-01220-x</a>.
  short: M. Wirth, H. Zhang, Annales Henri Poincare 24 (2023) 717–750.
corr_author: '1'
date_created: 2022-09-11T22:01:57Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2025-04-23T08:53:05Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s00023-022-01220-x
ec_funded: 1
external_id:
  arxiv:
  - '2105.08303'
  isi:
  - '000837499800002'
  pmid:
  - '36950223'
file:
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  checksum: 8c7b185eba5ccd92ef55c120f654222c
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  date_created: 2023-08-14T11:38:28Z
  date_updated: 2023-08-14T11:38:28Z
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has_accepted_license: '1'
intvolume: '        24'
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language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 717-750
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: eb958bca-77a9-11ec-83b8-c565cb50d8d6
  grant_number: M03337
  name: Curvature-dimension in noncommutative analysis
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
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  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Curvature-dimension conditions for symmetric quantum Markov semigroups
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2023'
...
---
_id: '12104'
abstract:
- lang: eng
  text: We study ergodic decompositions of Dirichlet spaces under intertwining via
    unitary order isomorphisms. We show that the ergodic decomposition of a quasi-regular
    Dirichlet space is unique up to a unique isomorphism of the indexing space. Furthermore,
    every unitary order isomorphism intertwining two quasi-regular Dirichlet spaces
    is decomposable over their ergodic decompositions up to conjugation via an isomorphism
    of the corresponding indexing spaces.
acknowledgement: Research supported by the Austrian Science Fund (FWF) grant F65 at
  the Institute of Science and Technology Austria and by the European Research Council
  (ERC) (Grant agreement No. 716117 awarded to Prof. Dr. Jan Maas). L.D.S. gratefully
  acknowledges funding of his current position by the Austrian Science Fund (FWF)
  through the ESPRIT Programme (Grant No. 208). M.W. gratefully acknowledges funding
  of his current position by the Austrian Science Fund (FWF) through the ESPRIT Programme
  (Grant No. 156).
article_number: '9'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lorenzo
  full_name: Dello Schiavo, Lorenzo
  id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
  last_name: Dello Schiavo
  orcid: 0000-0002-9881-6870
- first_name: Melchior
  full_name: Wirth, Melchior
  id: 88644358-0A0E-11EA-8FA5-49A33DDC885E
  last_name: Wirth
  orcid: 0000-0002-0519-4241
citation:
  ama: Dello Schiavo L, Wirth M. Ergodic decompositions of Dirichlet forms under order
    isomorphisms. <i>Journal of Evolution Equations</i>. 2023;23(1). doi:<a href="https://doi.org/10.1007/s00028-022-00859-7">10.1007/s00028-022-00859-7</a>
  apa: Dello Schiavo, L., &#38; Wirth, M. (2023). Ergodic decompositions of Dirichlet
    forms under order isomorphisms. <i>Journal of Evolution Equations</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00028-022-00859-7">https://doi.org/10.1007/s00028-022-00859-7</a>
  chicago: Dello Schiavo, Lorenzo, and Melchior Wirth. “Ergodic Decompositions of
    Dirichlet Forms under Order Isomorphisms.” <i>Journal of Evolution Equations</i>.
    Springer Nature, 2023. <a href="https://doi.org/10.1007/s00028-022-00859-7">https://doi.org/10.1007/s00028-022-00859-7</a>.
  ieee: L. Dello Schiavo and M. Wirth, “Ergodic decompositions of Dirichlet forms
    under order isomorphisms,” <i>Journal of Evolution Equations</i>, vol. 23, no.
    1. Springer Nature, 2023.
  ista: Dello Schiavo L, Wirth M. 2023. Ergodic decompositions of Dirichlet forms
    under order isomorphisms. Journal of Evolution Equations. 23(1), 9.
  mla: Dello Schiavo, Lorenzo, and Melchior Wirth. “Ergodic Decompositions of Dirichlet
    Forms under Order Isomorphisms.” <i>Journal of Evolution Equations</i>, vol. 23,
    no. 1, 9, Springer Nature, 2023, doi:<a href="https://doi.org/10.1007/s00028-022-00859-7">10.1007/s00028-022-00859-7</a>.
  short: L. Dello Schiavo, M. Wirth, Journal of Evolution Equations 23 (2023).
corr_author: '1'
date_created: 2023-01-08T23:00:53Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:45:56Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s00028-022-00859-7
ec_funded: 1
external_id:
  isi:
  - '000906214600004'
  pmid:
  - '36597554'
file:
- access_level: open_access
  checksum: 1f34f3e2cb521033de6154f274ea3a4e
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-20T10:45:06Z
  date_updated: 2023-01-20T10:45:06Z
  file_id: '12325'
  file_name: 2023_JourEvolutionEquations_DelloSchiavo.pdf
  file_size: 422612
  relation: main_file
  success: 1
file_date_updated: 2023-01-20T10:45:06Z
has_accepted_license: '1'
intvolume: '        23'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
- _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c
  grant_number: E208
  name: Configuration Spaces over Non-Smooth Spaces
- _id: 34c6ea2d-11ca-11ed-8bc3-c04f3c502833
  grant_number: ESP156_N
  name: Gradient flow techniques for quantum Markov semigroups
publication: Journal of Evolution Equations
publication_identifier:
  eissn:
  - 1424-3202
  issn:
  - 1424-3199
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ergodic decompositions of Dirichlet forms under order isomorphisms
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2023'
...
---
_id: '12106'
abstract:
- lang: eng
  text: Regulation of chromatin states involves the dynamic interplay between different
    histone modifications to control gene expression. Recent advances have enabled
    mapping of histone marks in single cells, but most methods are constrained to
    profile only one histone mark per cell. Here, we present an integrated experimental
    and computational framework, scChIX-seq (single-cell chromatin immunocleavage
    and unmixing sequencing), to map several histone marks in single cells. scChIX-seq
    multiplexes two histone marks together in single cells, then computationally deconvolves
    the signal using training data from respective histone mark profiles. This framework
    learns the cell-type-specific correlation structure between histone marks, and
    therefore does not require a priori assumptions of their genomic distributions.
    Using scChIX-seq, we demonstrate multimodal analysis of histone marks in single
    cells across a range of mark combinations. Modeling dynamics of in vitro macrophage
    differentiation enables integrated analysis of chromatin velocity. Overall, scChIX-seq
    unlocks systematic interrogation of the interplay between histone modifications
    in single cells.
acknowledgement: We thank M. van Loenhout for experimental advice on purifying cell
  types from the bone marrow, R. van der Linden for expertise with FACS and M. Blotenburg
  for help with cell typing the mouse organogenesis dataset. We thank M. Saraswat
  and O. Stegle for discussions on multinomial distributions. This work was supported
  by a European Research Council Advanced grant (ERC-AdG 742225-IntScOmics); Nederlandse
  Organisatie voor Wetenschappelijk Onderzoek (NWO) TOP grant (NWO CW 714.016.001)
  and NWO grant (OCENW.GROOT.2019.017); the Swiss National Science Foundation Early
  Postdoc Mobility (P2ELP3-184488 to P.Z. and P2BSP3-174991 to J.Y.); Marie Sklodowska-Curie
  Actions Postdoc (798573 to P.Z.) and the Human Frontier for Science Program Long-Term
  Fellowships (LT000209-2018-L to P.Z. and LT000097-2019-L to J.Y.). This work is
  part of the Oncode Institute which is financed partly by the Dutch Cancer Society.
article_processing_charge: No
article_type: original
author:
- first_name: Jake
  full_name: Yeung, Jake
  id: 123012b2-db30-11eb-b4d8-a35840c0551b
  last_name: Yeung
  orcid: 0000-0003-1732-1559
- first_name: Maria
  full_name: Florescu, Maria
  last_name: Florescu
- first_name: Peter
  full_name: Zeller, Peter
  last_name: Zeller
- first_name: Buys Anton
  full_name: De Barbanson, Buys Anton
  last_name: De Barbanson
- first_name: Max D.
  full_name: Wellenstein, Max D.
  last_name: Wellenstein
- first_name: Alexander
  full_name: Van Oudenaarden, Alexander
  last_name: Van Oudenaarden
citation:
  ama: Yeung J, Florescu M, Zeller P, De Barbanson BA, Wellenstein MD, Van Oudenaarden
    A. scChIX-seq infers dynamic relationships between histone modifications in single
    cells. <i>Nature Biotechnology</i>. 2023;41:813–823. doi:<a href="https://doi.org/10.1038/s41587-022-01560-3">10.1038/s41587-022-01560-3</a>
  apa: Yeung, J., Florescu, M., Zeller, P., De Barbanson, B. A., Wellenstein, M. D.,
    &#38; Van Oudenaarden, A. (2023). scChIX-seq infers dynamic relationships between
    histone modifications in single cells. <i>Nature Biotechnology</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41587-022-01560-3">https://doi.org/10.1038/s41587-022-01560-3</a>
  chicago: Yeung, Jake, Maria Florescu, Peter Zeller, Buys Anton De Barbanson, Max
    D. Wellenstein, and Alexander Van Oudenaarden. “ScChIX-Seq Infers Dynamic Relationships
    between Histone Modifications in Single Cells.” <i>Nature Biotechnology</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1038/s41587-022-01560-3">https://doi.org/10.1038/s41587-022-01560-3</a>.
  ieee: J. Yeung, M. Florescu, P. Zeller, B. A. De Barbanson, M. D. Wellenstein, and
    A. Van Oudenaarden, “scChIX-seq infers dynamic relationships between histone modifications
    in single cells,” <i>Nature Biotechnology</i>, vol. 41. Springer Nature, pp. 813–823,
    2023.
  ista: Yeung J, Florescu M, Zeller P, De Barbanson BA, Wellenstein MD, Van Oudenaarden
    A. 2023. scChIX-seq infers dynamic relationships between histone modifications
    in single cells. Nature Biotechnology. 41, 813–823.
  mla: Yeung, Jake, et al. “ScChIX-Seq Infers Dynamic Relationships between Histone
    Modifications in Single Cells.” <i>Nature Biotechnology</i>, vol. 41, Springer
    Nature, 2023, pp. 813–823, doi:<a href="https://doi.org/10.1038/s41587-022-01560-3">10.1038/s41587-022-01560-3</a>.
  short: J. Yeung, M. Florescu, P. Zeller, B.A. De Barbanson, M.D. Wellenstein, A.
    Van Oudenaarden, Nature Biotechnology 41 (2023) 813–823.
corr_author: '1'
date_created: 2023-01-08T23:00:53Z
date_published: 2023-06-01T00:00:00Z
date_updated: 2025-04-23T08:45:24Z
day: '01'
ddc:
- '570'
department:
- _id: ScienComp
doi: 10.1038/s41587-022-01560-3
external_id:
  isi:
  - '000909067600003'
  pmid:
  - '36593403'
file:
- access_level: open_access
  checksum: 668447a1c8d360b68f8aaf9e08ed644f
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T11:30:45Z
  date_updated: 2023-08-16T11:30:45Z
  file_id: '14066'
  file_name: 2023_NatureBioTech_Yeung.pdf
  file_size: 12040976
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T11:30:45Z
has_accepted_license: '1'
intvolume: '        41'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 813–823
pmid: 1
publication: Nature Biotechnology
publication_identifier:
  eissn:
  - 1546-1696
  issn:
  - 1087-0156
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: scChIX-seq infers dynamic relationships between histone modifications in single
  cells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2023'
...
---
_id: '12114'
abstract:
- lang: eng
  text: 'Probing the dynamics of aromatic side chains provides important insights
    into the behavior of a protein because flips of aromatic rings in a protein’s
    hydrophobic core report on breathing motion involving a large part of the protein.
    Inherently invisible to crystallography, aromatic motions have been primarily
    studied by solution NMR. The question how packing of proteins in crystals affects
    ring flips has, thus, remained largely unexplored. Here we apply magic-angle spinning
    NMR, advanced phenylalanine 1H-13C/2H isotope labeling and MD simulation to a
    protein in three different crystal packing environments to shed light onto possible
    impact of packing on ring flips. The flips of the two Phe residues in ubiquitin,
    both surface exposed, appear remarkably conserved in the different crystal forms,
    even though the intermolecular packing is quite different: Phe4 flips on a ca.
    10–20 ns time scale, and Phe45 are broadened in all crystals, presumably due to
    µs motion. Our findings suggest that intramolecular influences are more important
    for ring flips than intermolecular (packing) effects.'
acknowledgement: The NMR platform in Grenoble is part of the Grenoble Instruct-ERIC
  center (ISBG; UAR 3518 CNRS-CEA-UGA-EMBL) within the Grenoble Partnership for Structural
  Biology (PSB), supported by FRISBI (ANR-10-INBS-0005-02) and GRAL, financed within
  the University Grenoble Alpes graduate school (Ecoles Universitaires de Recherche)
  CBH-EUR-GS (ANR-17-EURE-0003). This work was supported by the European Research
  Council (StG-2012-311318-ProtDyn2Function to P.S.) and used the platforms of the
  Grenoble Instruct Center (ISBG; UMS 3518 CNRS-CEA-UJF-EMBL) with support from FRISBI
  (ANR-10-INSB-05–02) and GRAL (ANR-10-LABX-49–01) within the Grenoble Partnership
  for Structural Biology (PSB). We would like to thank Sergei Izmailov for developing
  and maintaining the pyxmolpp2 library. N.R.S. acknowledges support from St. Petersburg
  State University in a form of the grant 92425251 and the access to the MRR, MCT
  and CAMR resource centers. P.S. thanks Malcolm Levitt for pointing out the fact
  that “tensor asymmetry” is better called “tensor biaxiality”.
article_number: '100079'
article_processing_charge: No
article_type: original
author:
- first_name: Diego F.
  full_name: Gauto, Diego F.
  last_name: Gauto
- first_name: Olga O.
  full_name: Lebedenko, Olga O.
  last_name: Lebedenko
- first_name: Lea Marie
  full_name: Becker, Lea Marie
  id: 36336939-eb97-11eb-a6c2-c83f1214ca79
  last_name: Becker
  orcid: 0000-0002-6401-5151
- first_name: Isabel
  full_name: Ayala, Isabel
  last_name: Ayala
- first_name: Roman
  full_name: Lichtenecker, Roman
  last_name: Lichtenecker
- first_name: Nikolai R.
  full_name: Skrynnikov, Nikolai R.
  last_name: Skrynnikov
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: 'Gauto DF, Lebedenko OO, Becker LM, et al. Aromatic ring flips in differently
    packed ubiquitin protein crystals from MAS NMR and MD. <i>Journal of Structural
    Biology: X</i>. 2023;7. doi:<a href="https://doi.org/10.1016/j.yjsbx.2022.100079">10.1016/j.yjsbx.2022.100079</a>'
  apa: 'Gauto, D. F., Lebedenko, O. O., Becker, L. M., Ayala, I., Lichtenecker, R.,
    Skrynnikov, N. R., &#38; Schanda, P. (2023). Aromatic ring flips in differently
    packed ubiquitin protein crystals from MAS NMR and MD. <i>Journal of Structural
    Biology: X</i>. Elsevier. <a href="https://doi.org/10.1016/j.yjsbx.2022.100079">https://doi.org/10.1016/j.yjsbx.2022.100079</a>'
  chicago: 'Gauto, Diego F., Olga O. Lebedenko, Lea Marie Becker, Isabel Ayala, Roman
    Lichtenecker, Nikolai R. Skrynnikov, and Paul Schanda. “Aromatic Ring Flips in
    Differently Packed Ubiquitin Protein Crystals from MAS NMR and MD.” <i>Journal
    of Structural Biology: X</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.yjsbx.2022.100079">https://doi.org/10.1016/j.yjsbx.2022.100079</a>.'
  ieee: 'D. F. Gauto <i>et al.</i>, “Aromatic ring flips in differently packed ubiquitin
    protein crystals from MAS NMR and MD,” <i>Journal of Structural Biology: X</i>,
    vol. 7. Elsevier, 2023.'
  ista: 'Gauto DF, Lebedenko OO, Becker LM, Ayala I, Lichtenecker R, Skrynnikov NR,
    Schanda P. 2023. Aromatic ring flips in differently packed ubiquitin protein crystals
    from MAS NMR and MD. Journal of Structural Biology: X. 7, 100079.'
  mla: 'Gauto, Diego F., et al. “Aromatic Ring Flips in Differently Packed Ubiquitin
    Protein Crystals from MAS NMR and MD.” <i>Journal of Structural Biology: X</i>,
    vol. 7, 100079, Elsevier, 2023, doi:<a href="https://doi.org/10.1016/j.yjsbx.2022.100079">10.1016/j.yjsbx.2022.100079</a>.'
  short: 'D.F. Gauto, O.O. Lebedenko, L.M. Becker, I. Ayala, R. Lichtenecker, N.R.
    Skrynnikov, P. Schanda, Journal of Structural Biology: X 7 (2023).'
corr_author: '1'
date_created: 2023-01-12T11:55:38Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2024-10-09T21:04:02Z
day: '01'
ddc:
- '570'
department:
- _id: PaSc
doi: 10.1016/j.yjsbx.2022.100079
external_id:
  pmid:
  - '36578472'
file:
- access_level: open_access
  checksum: b4b1c10a31018aafe053b7d55a470e54
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T09:36:28Z
  date_updated: 2023-08-16T09:36:28Z
  file_id: '14064'
  file_name: 2023_JourStrucBiologyX_Gauto.pdf
  file_size: 5132322
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T09:36:28Z
has_accepted_license: '1'
intvolume: '         7'
keyword:
- Structural Biology
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: 'Journal of Structural Biology: X'
publication_identifier:
  issn:
  - 2590-1524
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Aromatic ring flips in differently packed ubiquitin protein crystals from MAS
  NMR and MD
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2023'
...
---
_id: '12115'
acknowledgement: This work was supported by European Commission’s Seventh Framework
  Programme under Grant Agreement No. 279113 (OCTIPS; www.octips.eu).
article_processing_charge: No
article_type: original
author:
- first_name: Jacek
  full_name: Glajzer, Jacek
  last_name: Glajzer
- first_name: Dan Cacsire
  full_name: Castillo-Tong, Dan Cacsire
  last_name: Castillo-Tong
- first_name: Rolf
  full_name: Richter, Rolf
  last_name: Richter
- first_name: Ignace
  full_name: Vergote, Ignace
  last_name: Vergote
- first_name: Hagen
  full_name: Kulbe, Hagen
  last_name: Kulbe
- first_name: Adriaan
  full_name: Vanderstichele, Adriaan
  last_name: Vanderstichele
- first_name: Ilary
  full_name: Ruscito, Ilary
  last_name: Ruscito
- first_name: Fabian
  full_name: Trillsch, Fabian
  last_name: Trillsch
- first_name: Alexander
  full_name: Mustea, Alexander
  last_name: Mustea
- first_name: Caroline
  full_name: Kreuzinger, Caroline
  id: 382077BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kreuzinger
- first_name: Charlie
  full_name: Gourley, Charlie
  last_name: Gourley
- first_name: Hani
  full_name: Gabra, Hani
  last_name: Gabra
- first_name: Eliane T.
  full_name: Taube, Eliane T.
  last_name: Taube
- first_name: Oliver
  full_name: Dorigo, Oliver
  last_name: Dorigo
- first_name: David
  full_name: Horst, David
  last_name: Horst
- first_name: Carlotta
  full_name: Keunecke, Carlotta
  last_name: Keunecke
- first_name: Joanna
  full_name: Baum, Joanna
  last_name: Baum
- first_name: Timothy
  full_name: Angelotti, Timothy
  last_name: Angelotti
- first_name: Jalid
  full_name: Sehouli, Jalid
  last_name: Sehouli
- first_name: Elena Ioana
  full_name: Braicu, Elena Ioana
  last_name: Braicu
citation:
  ama: 'Glajzer J, Castillo-Tong DC, Richter R, et al. ASO Visual Abstract: Impact
    of BRCA mutation status on tumor dissemination pattern, surgical outcome, and
    patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC).
    A multicenter, retrospective study of the ovarian cancer therapy—innovative models
    prolong survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. 2023;30:46-47.
    doi:<a href="https://doi.org/10.1245/s10434-022-12681-z">10.1245/s10434-022-12681-z</a>'
  apa: 'Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele,
    A., … Braicu, E. I. (2023). ASO Visual Abstract: Impact of BRCA mutation status
    on tumor dissemination pattern, surgical outcome, and patient survival in primary
    and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective
    study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS)
    consortium. <i>Annals of Surgical Oncology</i>. Springer Nature. <a href="https://doi.org/10.1245/s10434-022-12681-z">https://doi.org/10.1245/s10434-022-12681-z</a>'
  chicago: 'Glajzer, Jacek, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote,
    Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, et al. “ASO Visual Abstract:
    Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome,
    and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer
    (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy—Innovative
    Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>.
    Springer Nature, 2023. <a href="https://doi.org/10.1245/s10434-022-12681-z">https://doi.org/10.1245/s10434-022-12681-z</a>.'
  ieee: 'J. Glajzer <i>et al.</i>, “ASO Visual Abstract: Impact of BRCA mutation status
    on tumor dissemination pattern, surgical outcome, and patient survival in primary
    and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective
    study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS)
    consortium,” <i>Annals of Surgical Oncology</i>, vol. 30. Springer Nature, pp.
    46–47, 2023.'
  ista: 'Glajzer J, Castillo-Tong DC, Richter R, Vergote I, Kulbe H, Vanderstichele
    A, Ruscito I, Trillsch F, Mustea A, Kreuzinger C, Gourley C, Gabra H, Taube ET,
    Dorigo O, Horst D, Keunecke C, Baum J, Angelotti T, Sehouli J, Braicu EI. 2023.
    ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern,
    surgical outcome, and patient survival in primary and recurrent high-grade serous
    ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer
    therapy—innovative models prolong survival (OCTIPS) consortium. Annals of Surgical
    Oncology. 30, 46–47.'
  mla: 'Glajzer, Jacek, et al. “ASO Visual Abstract: Impact of BRCA Mutation Status
    on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary
    and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective
    Study of the Ovarian Cancer Therapy—Innovative Models Prolong Survival (OCTIPS)
    Consortium.” <i>Annals of Surgical Oncology</i>, vol. 30, Springer Nature, 2023,
    pp. 46–47, doi:<a href="https://doi.org/10.1245/s10434-022-12681-z">10.1245/s10434-022-12681-z</a>.'
  short: J. Glajzer, D.C. Castillo-Tong, R. Richter, I. Vergote, H. Kulbe, A. Vanderstichele,
    I. Ruscito, F. Trillsch, A. Mustea, C. Kreuzinger, C. Gourley, H. Gabra, E.T.
    Taube, O. Dorigo, D. Horst, C. Keunecke, J. Baum, T. Angelotti, J. Sehouli, E.I.
    Braicu, Annals of Surgical Oncology 30 (2023) 46–47.
date_created: 2023-01-12T11:56:22Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:43:43Z
day: '01'
department:
- _id: JoDa
doi: 10.1245/s10434-022-12681-z
external_id:
  isi:
  - '000879151800001'
intvolume: '        30'
isi: 1
keyword:
- Oncology
- Surgery
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1245/s10434-022-12681-z
month: '01'
oa: 1
oa_version: Published Version
page: 46-47
publication: Annals of Surgical Oncology
publication_identifier:
  eissn:
  - 1534-4681
  issn:
  - 1068-9265
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '12205'
    relation: other
    status: public
scopus_import: '1'
status: public
title: 'ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination
  pattern, surgical outcome, and patient survival in primary and recurrent high-grade
  serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian
  cancer therapy—innovative models prolong survival (OCTIPS) consortium'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2023'
...
---
_id: '12158'
abstract:
- lang: eng
  text: 'Post-translational histone modifications modulate chromatin activity to affect
    gene expression. How chromatin states underlie lineage choice in single cells
    is relatively unexplored. We develop sort-assisted single-cell chromatin immunocleavage
    (sortChIC) and map active (H3K4me1 and H3K4me3) and repressive (H3K27me3 and H3K9me3)
    histone modifications in the mouse bone marrow. During differentiation, hematopoietic
    stem and progenitor cells (HSPCs) acquire active chromatin states mediated by
    cell-type-specifying transcription factors, which are unique for each lineage.
    By contrast, most alterations in repressive marks during differentiation occur
    independent of the final cell type. Chromatin trajectory analysis shows that lineage
    choice at the chromatin level occurs at the progenitor stage. Joint profiling
    of H3K4me1 and H3K9me3 demonstrates that cell types within the myeloid lineage
    have distinct active chromatin but share similar myeloid-specific heterochromatin
    states. This implies a hierarchical regulation of chromatin during hematopoiesis:
    heterochromatin dynamics distinguish differentiation trajectories and lineages,
    while euchromatin dynamics reflect cell types within lineages.'
acknowledgement: We thank A. Giladi for sharing mRNA abundance tables of cell types
  together with J. van den Berg for critical reading of the manuscript. We thank M.
  Bartosovic for sharing method comparison data. pK19pA-MN was a gift from Ulrich
  Laemmli (Addgene plasmid 86973, http://n2t.net/addgene:86973; RRID:Addgene_86973).
  Figure 8 is adopted from Hematopoiesis (human) diagram by A. Rad and M. Häggström
  under CC-BY-SA 3.0 license. This work was supported by European Research Council
  Advanced under grant ERC-AdG 742225-IntScOmics and Nederlandse Organisatie voor
  Wetenschappelijk Onderzoek (NWO) TOP award NWO-CW 714.016.001. The SNF (P2BSP3-174991),
  HFSP (LT000209/2018-L) and Marie Skłodowska-Curie Actions (798573) supported P.Z.
  The SNF (P2ELP3_184488) and HFSP (LT000097/2019-L) supported J.Y. and the EMBO LTF
  (ALTF 1197–2019) supported V.B. This work is part of the Oncode Institute, which
  is partly financed by the Dutch Cancer Society. The funders had no role in study
  design, data collection and analysis, decision to publish or preparation of the
  manuscript.
article_processing_charge: No
article_type: review
author:
- first_name: Peter
  full_name: Zeller, Peter
  last_name: Zeller
- first_name: Jake
  full_name: Yeung, Jake
  id: 123012b2-db30-11eb-b4d8-a35840c0551b
  last_name: Yeung
  orcid: 0000-0003-1732-1559
- first_name: Helena
  full_name: Viñas Gaza, Helena
  last_name: Viñas Gaza
- first_name: Buys Anton
  full_name: de Barbanson, Buys Anton
  last_name: de Barbanson
- first_name: Vivek
  full_name: Bhardwaj, Vivek
  last_name: Bhardwaj
- first_name: Maria
  full_name: Florescu, Maria
  last_name: Florescu
- first_name: Reinier
  full_name: van der Linden, Reinier
  last_name: van der Linden
- first_name: Alexander
  full_name: van Oudenaarden, Alexander
  last_name: van Oudenaarden
citation:
  ama: Zeller P, Yeung J, Viñas Gaza H, et al. Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. 2023;55:333-345.
    doi:<a href="https://doi.org/10.1038/s41588-022-01260-3">10.1038/s41588-022-01260-3</a>
  apa: Zeller, P., Yeung, J., Viñas Gaza, H., de Barbanson, B. A., Bhardwaj, V., Florescu,
    M., … van Oudenaarden, A. (2023). Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41588-022-01260-3">https://doi.org/10.1038/s41588-022-01260-3</a>
  chicago: Zeller, Peter, Jake Yeung, Helena Viñas Gaza, Buys Anton de Barbanson,
    Vivek Bhardwaj, Maria Florescu, Reinier van der Linden, and Alexander van Oudenaarden.
    “Single-Cell SortChIC Identifies Hierarchical Chromatin Dynamics during Hematopoiesis.”
    <i>Nature Genetics</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41588-022-01260-3">https://doi.org/10.1038/s41588-022-01260-3</a>.
  ieee: P. Zeller <i>et al.</i>, “Single-cell sortChIC identifies hierarchical chromatin
    dynamics during hematopoiesis,” <i>Nature Genetics</i>, vol. 55. Springer Nature,
    pp. 333–345, 2023.
  ista: Zeller P, Yeung J, Viñas Gaza H, de Barbanson BA, Bhardwaj V, Florescu M,
    van der Linden R, van Oudenaarden A. 2023. Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. Nature Genetics. 55, 333–345.
  mla: Zeller, Peter, et al. “Single-Cell SortChIC Identifies Hierarchical Chromatin
    Dynamics during Hematopoiesis.” <i>Nature Genetics</i>, vol. 55, Springer Nature,
    2023, pp. 333–45, doi:<a href="https://doi.org/10.1038/s41588-022-01260-3">10.1038/s41588-022-01260-3</a>.
  short: P. Zeller, J. Yeung, H. Viñas Gaza, B.A. de Barbanson, V. Bhardwaj, M. Florescu,
    R. van der Linden, A. van Oudenaarden, Nature Genetics 55 (2023) 333–345.
date_created: 2023-01-12T12:09:09Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2025-04-23T08:45:00Z
day: '01'
ddc:
- '570'
- '000'
department:
- _id: ScienComp
doi: 10.1038/s41588-022-01260-3
external_id:
  pmid:
  - '36539617'
file:
- access_level: open_access
  checksum: 6fdb8e34fbeea63edd0f2c6c2cc5823e
  content_type: application/pdf
  creator: dernst
  date_created: 2023-02-27T07:46:45Z
  date_updated: 2023-02-27T07:46:45Z
  file_id: '12688'
  file_name: 2023_NatureGenetics_Zeller.pdf
  file_size: 21484855
  relation: main_file
  success: 1
file_date_updated: 2023-02-27T07:46:45Z
has_accepted_license: '1'
intvolume: '        55'
keyword:
- Genetics
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 333-345
pmid: 1
publication: Nature Genetics
publication_identifier:
  eissn:
  - 1546-1718
  issn:
  - 1061-4036
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2023'
...
---
_id: '12162'
abstract:
- lang: eng
  text: Homeostatic balance in the intestinal epithelium relies on a fast cellular
    turnover, which is coordinated by an intricate interplay between biochemical signalling,
    mechanical forces and organ geometry. We review recent modelling approaches that
    have been developed to understand different facets of this remarkable homeostatic
    equilibrium. Existing models offer different, albeit complementary, perspectives
    on the problem. First, biomechanical models aim to explain the local and global
    mechanical stresses driving cell renewal as well as tissue shape maintenance.
    Second, compartmental models provide insights into the conditions necessary to
    keep a constant flow of cells with well-defined ratios of cell types, and how
    perturbations can lead to an unbalance of relative compartment sizes. A third
    family of models address, at the cellular level, the nature and regulation of
    stem fate choices that are necessary to fuel cellular turnover. We also review
    how these different approaches are starting to be integrated together across scales,
    to provide quantitative predictions and new conceptual frameworks to think about
    the dynamics of cell renewal in complex tissues.
acknowledgement: "This work received funding from the ERC under the European Union’s
  Horizon 2020 research and innovation programme (grant agreement No. 851288 to E.H.).\r\nB.
  C-M wants to acknowledge the support of the field of excellence Complexity of Life,
  in Basic Research and Innovation of the University of Graz."
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Bernat
  full_name: Corominas-Murtra, Bernat
  id: 43BE2298-F248-11E8-B48F-1D18A9856A87
  last_name: Corominas-Murtra
  orcid: 0000-0001-9806-5643
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
citation:
  ama: Corominas-Murtra B, Hannezo EB. Modelling the dynamics of mammalian gut homeostasis.
    <i>Seminars in Cell &#38; Developmental Biology</i>. 2023;150-151:58-65. doi:<a
    href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>
  apa: Corominas-Murtra, B., &#38; Hannezo, E. B. (2023). Modelling the dynamics of
    mammalian gut homeostasis. <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>
  chicago: Corominas-Murtra, Bernat, and Edouard B Hannezo. “Modelling the Dynamics
    of Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>.
  ieee: B. Corominas-Murtra and E. B. Hannezo, “Modelling the dynamics of mammalian
    gut homeostasis,” <i>Seminars in Cell &#38; Developmental Biology</i>, vol. 150–151.
    Elsevier, pp. 58–65, 2023.
  ista: Corominas-Murtra B, Hannezo EB. 2023. Modelling the dynamics of mammalian
    gut homeostasis. Seminars in Cell &#38; Developmental Biology. 150–151, 58–65.
  mla: Corominas-Murtra, Bernat, and Edouard B. Hannezo. “Modelling the Dynamics of
    Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>,
    vol. 150–151, Elsevier, 2023, pp. 58–65, doi:<a href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>.
  short: B. Corominas-Murtra, E.B. Hannezo, Seminars in Cell &#38; Developmental Biology
    150–151 (2023) 58–65.
corr_author: '1'
date_created: 2023-01-12T12:09:47Z
date_published: 2023-12-02T00:00:00Z
date_updated: 2025-04-14T07:52:27Z
day: '02'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1016/j.semcdb.2022.11.005
ec_funded: 1
external_id:
  isi:
  - '001053522200001'
  pmid:
  - '36470715'
file:
- access_level: open_access
  checksum: c619887cf130f4649bf3035417186004
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-08T10:16:04Z
  date_updated: 2024-01-08T10:16:04Z
  file_id: '14741'
  file_name: 2023_SeminarsCellDevBiology_CorominasMurtra.pdf
  file_size: 1343750
  relation: main_file
  success: 1
file_date_updated: 2024-01-08T10:16:04Z
has_accepted_license: '1'
isi: 1
keyword:
- Cell Biology
- Developmental Biology
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 58-65
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: Seminars in Cell & Developmental Biology
publication_identifier:
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling the dynamics of mammalian gut homeostasis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 150-151
year: '2023'
...
---
_id: '12163'
abstract:
- lang: eng
  text: Small GTPases play essential roles in the organization of eukaryotic cells.
    In recent years, it has become clear that their intracellular functions result
    from intricate biochemical networks of the GTPase and their regulators that dynamically
    bind to a membrane surface. Due to the inherent complexities of their interactions,
    however, revealing the underlying mechanisms of action is often difficult to achieve
    from in vivo studies. This review summarizes in vitro reconstitution approaches
    developed to obtain a better mechanistic understanding of how small GTPase activities
    are regulated in space and time.
acknowledgement: The authors acknowledge support from IST Austria and helpful comments
  from the anonymous reviewers that helped to improve this manuscript. We apologize
  to the authors of primary literature and outstanding research not cited here due
  to space restraints.
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Albert
  full_name: Auer, Albert
  id: 3018E8C2-F248-11E8-B48F-1D18A9856A87
  last_name: Auer
  orcid: 0000-0002-3580-2906
- first_name: Gabriel
  full_name: Brognara, Gabriel
  id: D96FFDA0-A884-11E9-9968-DC26E6697425
  last_name: Brognara
- first_name: Hanifatul R
  full_name: Budiman, Hanifatul R
  id: 55380f95-15b2-11ec-abd3-aff8e230696b
  last_name: Budiman
- first_name: Lukasz M
  full_name: Kowalski, Lukasz M
  id: e3a512e2-4bbe-11eb-a68a-e3857a7844c2
  last_name: Kowalski
- first_name: Ivana
  full_name: Matijevic, Ivana
  id: 83c17ce3-15b2-11ec-abd3-f486545870bd
  last_name: Matijevic
citation:
  ama: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. In vitro
    reconstitution of small GTPase regulation. <i>FEBS Letters</i>. 2023;597(6):762-777.
    doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>
  apa: Loose, M., Auer, A., Brognara, G., Budiman, H. R., Kowalski, L. M., &#38; Matijevic,
    I. (2023). In vitro reconstitution of small GTPase regulation. <i>FEBS Letters</i>.
    Wiley. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>
  chicago: Loose, Martin, Albert Auer, Gabriel Brognara, Hanifatul R Budiman, Lukasz
    M Kowalski, and Ivana Matijevic. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>. Wiley, 2023. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>.
  ieee: M. Loose, A. Auer, G. Brognara, H. R. Budiman, L. M. Kowalski, and I. Matijevic,
    “In vitro reconstitution of small GTPase regulation,” <i>FEBS Letters</i>, vol.
    597, no. 6. Wiley, pp. 762–777, 2023.
  ista: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. 2023. In
    vitro reconstitution of small GTPase regulation. FEBS Letters. 597(6), 762–777.
  mla: Loose, Martin, et al. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>, vol. 597, no. 6, Wiley, 2023, pp. 762–77, doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>.
  short: M. Loose, A. Auer, G. Brognara, H.R. Budiman, L.M. Kowalski, I. Matijevic,
    FEBS Letters 597 (2023) 762–777.
corr_author: '1'
date_created: 2023-01-12T12:09:58Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2024-10-09T21:03:42Z
day: '01'
ddc:
- '570'
department:
- _id: MaLo
doi: 10.1002/1873-3468.14540
external_id:
  isi:
  - '000891573000001'
  pmid:
  - '36448231'
file:
- access_level: open_access
  checksum: 7492244d3f9c5faa1347ef03f6e5bc84
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T08:31:04Z
  date_updated: 2023-08-16T08:31:04Z
  file_id: '14063'
  file_name: 2023_FEBSLetters_Loose.pdf
  file_size: 3148143
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T08:31:04Z
has_accepted_license: '1'
intvolume: '       597'
isi: 1
issue: '6'
keyword:
- Cell Biology
- Genetics
- Molecular Biology
- Biochemistry
- Structural Biology
- Biophysics
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 762-777
pmid: 1
publication: FEBS Letters
publication_identifier:
  eissn:
  - 1873-3468
  issn:
  - 0014-5793
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: In vitro reconstitution of small GTPase regulation
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 597
year: '2023'
...
---
_id: '12164'
abstract:
- lang: eng
  text: 'A shared-memory counter is a widely-used and well-studied concurrent object.
    It supports two operations: An Inc operation that increases its value by 1 and
    a Read operation that returns its current value. In Jayanti et al (SIAM J Comput,
    30(2), 2000), Jayanti, Tan and Toueg proved a linear lower bound on the worst-case
    step complexity of obstruction-free implementations, from read-write registers,
    of a large class of shared objects that includes counters. The lower bound leaves
    open the question of finding counter implementations with sub-linear amortized
    step complexity. In this work, we address this gap. We show that n-process, wait-free
    and linearizable counters can be implemented from read-write registers with O(log2n)
    amortized step complexity. This is the first counter algorithm from read-write
    registers that provides sub-linear amortized step complexity in executions of
    arbitrary length. Since a logarithmic lower bound on the amortized step complexity
    of obstruction-free counter implementations exists, our upper bound is within
    a logarithmic factor of the optimal. The worst-case step complexity of the construction
    remains linear, which is optimal. This is obtained thanks to a new max register
    construction with O(logn) amortized step complexity in executions of arbitrary
    length in which the value stored in the register does not grow too quickly. We
    then leverage an existing counter algorithm by Aspnes, Attiya and Censor-Hillel
    [1] in which we “plug” our max register implementation to show that it remains
    linearizable while achieving O(log2n) amortized step complexity.'
acknowledgement: A preliminary version of this work appeared in DISC’19. Mirza Ahad
  Baig, Alessia Milani and Corentin Travers are supported by ANR projects Descartes
  and FREDDA. Mirza Ahad Baig is supported by UMI Relax. Danny Hendler is supported
  by the Israel Science Foundation (Grants 380/18 and 1425/22).
article_processing_charge: No
article_type: original
author:
- first_name: Mirza Ahad
  full_name: Baig, Mirza Ahad
  id: 3EDE6DE4-AA5A-11E9-986D-341CE6697425
  last_name: Baig
- first_name: Danny
  full_name: Hendler, Danny
  last_name: Hendler
- first_name: Alessia
  full_name: Milani, Alessia
  last_name: Milani
- first_name: Corentin
  full_name: Travers, Corentin
  last_name: Travers
citation:
  ama: Baig MA, Hendler D, Milani A, Travers C. Long-lived counters with polylogarithmic
    amortized step complexity. <i>Distributed Computing</i>. 2023;36:29-43. doi:<a
    href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>
  apa: Baig, M. A., Hendler, D., Milani, A., &#38; Travers, C. (2023). Long-lived
    counters with polylogarithmic amortized step complexity. <i>Distributed Computing</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>
  chicago: Baig, Mirza Ahad, Danny Hendler, Alessia Milani, and Corentin Travers.
    “Long-Lived Counters with Polylogarithmic Amortized Step Complexity.” <i>Distributed
    Computing</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>.
  ieee: M. A. Baig, D. Hendler, A. Milani, and C. Travers, “Long-lived counters with
    polylogarithmic amortized step complexity,” <i>Distributed Computing</i>, vol.
    36. Springer Nature, pp. 29–43, 2023.
  ista: Baig MA, Hendler D, Milani A, Travers C. 2023. Long-lived counters with polylogarithmic
    amortized step complexity. Distributed Computing. 36, 29–43.
  mla: Baig, Mirza Ahad, et al. “Long-Lived Counters with Polylogarithmic Amortized
    Step Complexity.” <i>Distributed Computing</i>, vol. 36, Springer Nature, 2023,
    pp. 29–43, doi:<a href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>.
  short: M.A. Baig, D. Hendler, A. Milani, C. Travers, Distributed Computing 36 (2023)
    29–43.
date_created: 2023-01-12T12:10:08Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:39:36Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/s00446-022-00439-5
external_id:
  isi:
  - '000890138700001'
intvolume: '        36'
isi: 1
keyword:
- Computational Theory and Mathematics
- Computer Networks and Communications
- Hardware and Architecture
- Theoretical Computer Science
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://drops.dagstuhl.de/opus/volltexte/2019/11310/
month: '03'
oa: 1
oa_version: Preprint
page: 29-43
publication: Distributed Computing
publication_identifier:
  eissn:
  - 1432-0452
  issn:
  - 0178-2770
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Long-lived counters with polylogarithmic amortized step complexity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2023'
...
---
OA_type: free access
_id: '12166'
abstract:
- lang: eng
  text: Kerstin Johannesson is a marine ecologist and evolutionary biologist based
    at the Tjärnö Marine Laboratory of the University of Gothenburg, which is situated
    in the beautiful Kosterhavet National Park on the Swedish west coast. Her work,
    using marine periwinkles (especially Littorina saxatilis and L. fabalis) as main
    model systems, has made a remarkable contribution to marine evolutionary biology
    and our understanding of local adaptation and its genetic underpinnings.
article_processing_charge: No
article_type: editorial
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: Westram AM, Butlin R. Professor Kerstin Johannesson–winner of the 2022 Molecular
    Ecology Prize. <i>Molecular Ecology</i>. 2023;32(1):26-29. doi:<a href="https://doi.org/10.1111/mec.16779">10.1111/mec.16779</a>
  apa: Westram, A. M., &#38; Butlin, R. (2023). Professor Kerstin Johannesson–winner
    of the 2022 Molecular Ecology Prize. <i>Molecular Ecology</i>. Wiley. <a href="https://doi.org/10.1111/mec.16779">https://doi.org/10.1111/mec.16779</a>
  chicago: Westram, Anja M, and Roger Butlin. “Professor Kerstin Johannesson–Winner
    of the 2022 Molecular Ecology Prize.” <i>Molecular Ecology</i>. Wiley, 2023. <a
    href="https://doi.org/10.1111/mec.16779">https://doi.org/10.1111/mec.16779</a>.
  ieee: A. M. Westram and R. Butlin, “Professor Kerstin Johannesson–winner of the
    2022 Molecular Ecology Prize,” <i>Molecular Ecology</i>, vol. 32, no. 1. Wiley,
    pp. 26–29, 2023.
  ista: Westram AM, Butlin R. 2023. Professor Kerstin Johannesson–winner of the 2022
    Molecular Ecology Prize. Molecular Ecology. 32(1), 26–29.
  mla: Westram, Anja M., and Roger Butlin. “Professor Kerstin Johannesson–Winner of
    the 2022 Molecular Ecology Prize.” <i>Molecular Ecology</i>, vol. 32, no. 1, Wiley,
    2023, pp. 26–29, doi:<a href="https://doi.org/10.1111/mec.16779">10.1111/mec.16779</a>.
  short: A.M. Westram, R. Butlin, Molecular Ecology 32 (2023) 26–29.
corr_author: '1'
date_created: 2023-01-12T12:10:28Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:44:33Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/mec.16779
external_id:
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keyword:
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language:
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publication: Molecular Ecology
publication_identifier:
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publication_status: published
publisher: Wiley
quality_controlled: '1'
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status: public
title: Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2023'
...
