---
OA_place: publisher
_id: '18225'
abstract:
- lang: eng
  text: "Isometric feature mapping is an established time-honored algorithm in manifold
    learning and non-linear dimensionality reduction. Its prominence can be attributed
    to the output of a coherent global low-dimensional representation of data by preserving
    intrinsic distances. In order to enable an efficient and more applicable isometric
    feature mapping, a diverse set of sophisticated advancements have been proposed
    to the original algorithm to incorporate important factors like sparsity of computation,
    conformality, topological constraints and spectral geometry. However, a significant
    shortcoming of most approaches is the dependence on large-scale dense-spectral
    decompositions and the inability to generalize to points far away from the sampling
    of the manifold.\r\nIn this paper, we explore an unsupervised deep learning approach
    for computing distance-preserving maps for non-linear dimensionality reduction.
    We demonstrate that our framework is general enough to incorporate all previous
    advancements and show a significantly improved local and non-local generalization
    of the isometric mapping. Our approach involves training with only a few landmark
    points and avoids the need for population of dense matrices as well as computing
    their spectral decomposition."
article_number: '104461'
article_processing_charge: No
article_type: original
author:
- first_name: Gautam
  full_name: Pai, Gautam
  last_name: Pai
- first_name: Alexander
  full_name: Bronstein, Alexander
  id: 58f3726e-7cba-11ef-ad8b-e6e8cb3904e6
  last_name: Bronstein
  orcid: 0000-0001-9699-8730
- first_name: Ronen
  full_name: Talmon, Ronen
  last_name: Talmon
- first_name: Ron
  full_name: Kimmel, Ron
  last_name: Kimmel
citation:
  ama: Pai G, Bronstein AM, Talmon R, Kimmel R. Deep isometric maps. <i>Image and
    Vision Computing</i>. 2022;123. doi:<a href="https://doi.org/10.1016/j.imavis.2022.104461">10.1016/j.imavis.2022.104461</a>
  apa: Pai, G., Bronstein, A. M., Talmon, R., &#38; Kimmel, R. (2022). Deep isometric
    maps. <i>Image and Vision Computing</i>. Elsevier. <a href="https://doi.org/10.1016/j.imavis.2022.104461">https://doi.org/10.1016/j.imavis.2022.104461</a>
  chicago: Pai, Gautam, Alex M. Bronstein, Ronen Talmon, and Ron Kimmel. “Deep Isometric
    Maps.” <i>Image and Vision Computing</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.imavis.2022.104461">https://doi.org/10.1016/j.imavis.2022.104461</a>.
  ieee: G. Pai, A. M. Bronstein, R. Talmon, and R. Kimmel, “Deep isometric maps,”
    <i>Image and Vision Computing</i>, vol. 123. Elsevier, 2022.
  ista: Pai G, Bronstein AM, Talmon R, Kimmel R. 2022. Deep isometric maps. Image
    and Vision Computing. 123, 104461.
  mla: Pai, Gautam, et al. “Deep Isometric Maps.” <i>Image and Vision Computing</i>,
    vol. 123, 104461, Elsevier, 2022, doi:<a href="https://doi.org/10.1016/j.imavis.2022.104461">10.1016/j.imavis.2022.104461</a>.
  short: G. Pai, A.M. Bronstein, R. Talmon, R. Kimmel, Image and Vision Computing
    123 (2022).
date_created: 2024-10-08T12:54:22Z
date_published: 2022-07-01T00:00:00Z
date_updated: 2024-10-14T11:03:26Z
day: '01'
doi: 10.1016/j.imavis.2022.104461
extern: '1'
intvolume: '       123'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.imavis.2022.104461
month: '07'
oa: 1
oa_version: Published Version
publication: Image and Vision Computing
publication_identifier:
  issn:
  - 0262-8856
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deep isometric maps
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 123
year: '2022'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18226'
abstract:
- lang: eng
  text: Spontaneous parametric downconversion (SPDC) in quantum optics is an invaluable
    resource for the realization of high-dimensional qudits with spatial modes of
    light. One of the main open challenges is how to directly generate a desirable
    qudit state in the SPDC process. This problem can be addressed through advanced
    computational learning methods; however, due to difficulties in modeling the SPDC
    process by a fully differentiable algorithm, progress has been limited. Here,
    we overcome these limitations and introduce a physically constrained and differentiable
    model, validated against experimental results for shaped pump beams and structured
    crystals, capable of learning the relevant interaction parameters in the process.
    We avoid any restrictions induced by the stochastic nature of our physical model
    and integrate the dynamic equations governing the evolution under the SPDC Hamiltonian.
    We solve the inverse problem of designing a nonlinear quantum optical system that
    achieves the desired quantum state of downconverted photon pairs. The desired
    states are defined using either the second-order correlations between different
    spatial modes or by specifying the required density matrix. By learning nonlinear
    photonic crystal structures as well as different pump shapes, we successfully
    show how to generate maximally entangled states. Furthermore, we simulate all-optical
    coherent control over the generated quantum state by actively changing the profile
    of the pump beam. Our work can be useful for applications such as novel designs
    of high-dimensional quantum key distribution and quantum information processing
    protocols. In addition, our method can be readily applied for controlling other
    degrees of freedom of light in the SPDC process, such as spectral and temporal
    properties, and may even be used in condensed-matter systems having a similar
    interaction Hamiltonian.
article_processing_charge: No
article_type: original
author:
- first_name: Eyal
  full_name: Rozenberg, Eyal
  last_name: Rozenberg
- first_name: Aviv
  full_name: Karnieli, Aviv
  last_name: Karnieli
- first_name: Ofir
  full_name: Yesharim, Ofir
  last_name: Yesharim
- first_name: Joshua
  full_name: Foley-Comer, Joshua
  last_name: Foley-Comer
- first_name: Sivan
  full_name: Trajtenberg-Mills, Sivan
  last_name: Trajtenberg-Mills
- first_name: Daniel
  full_name: Freedman, Daniel
  last_name: Freedman
- first_name: Alexander
  full_name: Bronstein, Alexander
  id: 58f3726e-7cba-11ef-ad8b-e6e8cb3904e6
  last_name: Bronstein
  orcid: 0000-0001-9699-8730
- first_name: Ady
  full_name: Arie, Ady
  last_name: Arie
citation:
  ama: Rozenberg E, Karnieli A, Yesharim O, et al. Inverse design of spontaneous parametric
    downconversion for generation of high-dimensional qudits. <i>Optica</i>. 2022;9(6):602-615.
    doi:<a href="https://doi.org/10.1364/optica.451115">10.1364/optica.451115</a>
  apa: Rozenberg, E., Karnieli, A., Yesharim, O., Foley-Comer, J., Trajtenberg-Mills,
    S., Freedman, D., … Arie, A. (2022). Inverse design of spontaneous parametric
    downconversion for generation of high-dimensional qudits. <i>Optica</i>. Optica
    Publishing Group. <a href="https://doi.org/10.1364/optica.451115">https://doi.org/10.1364/optica.451115</a>
  chicago: Rozenberg, Eyal, Aviv Karnieli, Ofir Yesharim, Joshua Foley-Comer, Sivan
    Trajtenberg-Mills, Daniel Freedman, Alex M. Bronstein, and Ady Arie. “Inverse
    Design of Spontaneous Parametric Downconversion for Generation of High-Dimensional
    Qudits.” <i>Optica</i>. Optica Publishing Group, 2022. <a href="https://doi.org/10.1364/optica.451115">https://doi.org/10.1364/optica.451115</a>.
  ieee: E. Rozenberg <i>et al.</i>, “Inverse design of spontaneous parametric downconversion
    for generation of high-dimensional qudits,” <i>Optica</i>, vol. 9, no. 6. Optica
    Publishing Group, pp. 602–615, 2022.
  ista: Rozenberg E, Karnieli A, Yesharim O, Foley-Comer J, Trajtenberg-Mills S, Freedman
    D, Bronstein AM, Arie A. 2022. Inverse design of spontaneous parametric downconversion
    for generation of high-dimensional qudits. Optica. 9(6), 602–615.
  mla: Rozenberg, Eyal, et al. “Inverse Design of Spontaneous Parametric Downconversion
    for Generation of High-Dimensional Qudits.” <i>Optica</i>, vol. 9, no. 6, Optica
    Publishing Group, 2022, pp. 602–15, doi:<a href="https://doi.org/10.1364/optica.451115">10.1364/optica.451115</a>.
  short: E. Rozenberg, A. Karnieli, O. Yesharim, J. Foley-Comer, S. Trajtenberg-Mills,
    D. Freedman, A.M. Bronstein, A. Arie, Optica 9 (2022) 602–615.
date_created: 2024-10-08T12:54:43Z
date_published: 2022-06-06T00:00:00Z
date_updated: 2024-10-14T11:07:29Z
day: '06'
doi: 10.1364/optica.451115
extern: '1'
intvolume: '         9'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1364/OPTICA.451115
month: '06'
oa: 1
oa_version: Published Version
page: 602-615
publication: Optica
publication_identifier:
  issn:
  - 2334-2536
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inverse design of spontaneous parametric downconversion for generation of high-dimensional
  qudits
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2022'
...
---
_id: '18229'
abstract:
- lang: eng
  text: We present Self-Classifier – a novel self-supervised end-to-end classification
    learning approach. Self-Classifier learns labels and representations simultaneously
    in a single-stage end-to-end manner by optimizing for same-class prediction of
    two augmented views of the same sample. To guarantee non-degenerate solutions
    (i.e., solutions where all labels are assigned to the same class) we propose a
    mathematically motivated variant of the cross-entropy loss that has a uniform
    prior asserted on the predicted labels. In our theoretical analysis, we prove
    that degenerate solutions are not in the set of optimal solutions of our approach.
    Self-Classifier is simple to implement and scalable. Unlike other popular unsupervised
    classification and contrastive representation learning approaches, it does not
    require any form of pre-training, expectation-maximization, pseudo-labeling, external
    clustering, a second network, stop-gradient operation, or negative pairs. Despite
    its simplicity, our approach sets a new state of the art for unsupervised classification
    of ImageNet; and even achieves comparable to state-of-the-art results for unsupervised
    representation learning. Code is available at https://github.com/elad-amrani/self-classifier.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Elad
  full_name: Amrani, Elad
  last_name: Amrani
- first_name: Leonid
  full_name: Karlinsky, Leonid
  last_name: Karlinsky
- first_name: Alexander
  full_name: Bronstein, Alexander
  id: 58f3726e-7cba-11ef-ad8b-e6e8cb3904e6
  last_name: Bronstein
  orcid: 0000-0001-9699-8730
citation:
  ama: 'Amrani E, Karlinsky L, Bronstein AM. Self-supervised classification network.
    In: <i>17th European Conference on Computer Vision</i>. Vol 13691. Springer Nature;
    2022:116-132. doi:<a href="https://doi.org/10.1007/978-3-031-19821-2_7">10.1007/978-3-031-19821-2_7</a>'
  apa: 'Amrani, E., Karlinsky, L., &#38; Bronstein, A. M. (2022). Self-supervised
    classification network. In <i>17th European Conference on Computer Vision</i>
    (Vol. 13691, pp. 116–132). Tel Aviv, Israel: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-19821-2_7">https://doi.org/10.1007/978-3-031-19821-2_7</a>'
  chicago: Amrani, Elad, Leonid Karlinsky, and Alex M. Bronstein. “Self-Supervised
    Classification Network.” In <i>17th European Conference on Computer Vision</i>,
    13691:116–32. Springer Nature, 2022. <a href="https://doi.org/10.1007/978-3-031-19821-2_7">https://doi.org/10.1007/978-3-031-19821-2_7</a>.
  ieee: E. Amrani, L. Karlinsky, and A. M. Bronstein, “Self-supervised classification
    network,” in <i>17th European Conference on Computer Vision</i>, Tel Aviv, Israel,
    2022, vol. 13691, pp. 116–132.
  ista: 'Amrani E, Karlinsky L, Bronstein AM. 2022. Self-supervised classification
    network. 17th European Conference on Computer Vision. ECCV: European Conference
    on Computer Vision, LNCS, vol. 13691, 116–132.'
  mla: Amrani, Elad, et al. “Self-Supervised Classification Network.” <i>17th European
    Conference on Computer Vision</i>, vol. 13691, Springer Nature, 2022, pp. 116–32,
    doi:<a href="https://doi.org/10.1007/978-3-031-19821-2_7">10.1007/978-3-031-19821-2_7</a>.
  short: E. Amrani, L. Karlinsky, A.M. Bronstein, in:, 17th European Conference on
    Computer Vision, Springer Nature, 2022, pp. 116–132.
conference:
  end_date: 2022-10-27
  location: Tel Aviv, Israel
  name: 'ECCV: European Conference on Computer Vision'
  start_date: 2022-10-23
date_created: 2024-10-08T12:55:44Z
date_published: 2022-10-23T00:00:00Z
date_updated: 2024-10-15T07:04:39Z
day: '23'
doi: 10.1007/978-3-031-19821-2_7
extern: '1'
external_id:
  arxiv:
  - '2103.10994'
intvolume: '     13691'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2103.10994
month: '10'
oa: 1
oa_version: None
page: 116-132
publication: 17th European Conference on Computer Vision
publication_identifier:
  eisbn:
  - '9783031198212'
  eissn:
  - 1611-3349
  isbn:
  - '9783031198205'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/elad-amrani/self-classifier
scopus_import: '1'
status: public
title: Self-supervised classification network
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13691
year: '2022'
...
---
_id: '18291'
article_processing_charge: No
author:
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
- first_name: Daniel
  full_name: Jirovec, Daniel
  id: 4C473F58-F248-11E8-B48F-1D18A9856A87
  last_name: Jirovec
  orcid: 0000-0002-7197-4801
citation:
  ama: "Katsaros G, Jirovec D. Dynamics of Hole Singlet-Triplet Qubits with Large
    \U0001D454-Factor Differences. 2022. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18291\">10.15479/AT:ISTA:18291</a>"
  apa: "Katsaros, G., &#38; Jirovec, D. (2022). Dynamics of Hole Singlet-Triplet Qubits
    with Large \U0001D454-Factor Differences. Institute of Science and Technology
    Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:18291\">https://doi.org/10.15479/AT:ISTA:18291</a>"
  chicago: "Katsaros, Georgios, and Daniel Jirovec. “Dynamics of Hole Singlet-Triplet
    Qubits with Large \U0001D454-Factor Differences.” Institute of Science and Technology
    Austria, 2022. <a href=\"https://doi.org/10.15479/AT:ISTA:18291\">https://doi.org/10.15479/AT:ISTA:18291</a>."
  ieee: "G. Katsaros and D. Jirovec, “Dynamics of Hole Singlet-Triplet Qubits with
    Large \U0001D454-Factor Differences.” Institute of Science and Technology Austria,
    2022."
  ista: "Katsaros G, Jirovec D. 2022. Dynamics of Hole Singlet-Triplet Qubits with
    Large \U0001D454-Factor Differences, Institute of Science and Technology Austria,
    <a href=\"https://doi.org/10.15479/AT:ISTA:18291\">10.15479/AT:ISTA:18291</a>."
  mla: "Katsaros, Georgios, and Daniel Jirovec. <i>Dynamics of Hole Singlet-Triplet
    Qubits with Large \U0001D454-Factor Differences</i>. Institute of Science and
    Technology Austria, 2022, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18291\">10.15479/AT:ISTA:18291</a>."
  short: G. Katsaros, D. Jirovec, (2022).
corr_author: '1'
date_created: 2024-10-09T19:35:03Z
date_published: 2022-03-01T00:00:00Z
date_updated: 2025-04-15T07:15:24Z
day: '01'
department:
- _id: GeKa
doi: 10.15479/AT:ISTA:18291
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  date_created: 2024-10-14T18:11:45Z
  date_updated: 2024-10-14T18:11:45Z
  file_id: '18442'
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  file_size: 6776
  relation: main_file
  success: 1
file_date_updated: 2024-10-14T18:11:45Z
has_accepted_license: '1'
license: https://creativecommons.org/licenses/by/4.0/
month: '03'
oa: 1
oa_version: None
publisher: Institute of Science and Technology Austria
related_material:
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  - id: '10920'
    relation: research_paper
    status: public
status: public
title: "Dynamics of Hole Singlet-Triplet Qubits with Large \U0001D454-Factor Differences"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2022'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '18606'
abstract:
- lang: eng
  text: "Shear thickening is an intriguing rheological behaviour which consists in
    a brutal increase in the viscosity above a critical shear rate. It is famously
    encountered in suspensions of corn starch in water. Despite having been discovered
    in the early 1930's, its underlying mechanisms remained a mystery for a long time.
    In 2013–14, numerical and theoretical works [[1], [2], [3]] put forward a frictional
    transition scenario to explain this phenomenon.\r\nIn this talk, I will present
    experimental work investigating this frictional transition scenario. In order
    to test the ideas of this model, one has to go further than standard rheological
    techniques, since they do not provide access to the frictional state of the measured
    suspension. I will thus focus on the techniques that we developed in order to
    evidence the frictional transition and link it to the presence of a shear-thickening
    behaviour."
acknowledgement: "This talk presents parts of my PhD work, conducted at IUSTI in Marseille
  under the supervision of Yoël Forterre and Bloen Metzger. It aslo benefited from
  contributions from Antoine Bérut, and some of the data was acquired by Pauline Dame
  as part of a summer internship.\r\nThis work was supported by the European Research
  Council (ERC) under the European Union Horizon 2020 Research and Innovation program
  (ERC Grant 647384) and by the Labex MEC (ANR-10-LABX-0092) under the 647384) and
  by the A*MIDEX project (ANR-11-IDEX-0001-02) funded by the French government program
  Investissements d'Avenir, and by ANR ScienceFriction (No. ANR-18-CE30-0024)."
article_number: '100038'
article_processing_charge: No
article_type: original
author:
- first_name: Cécile
  full_name: Clavaud, Cécile
  id: 5f654c5d-04a1-11eb-ab36-ba9ffec58bd8
  last_name: Clavaud
  orcid: 0000-0002-1843-3803
citation:
  ama: 'Clavaud C. Shear thickening in dense suspensions: an experimental study. <i>Science
    Talks</i>. 2022;3. doi:<a href="https://doi.org/10.1016/j.sctalk.2022.100038">10.1016/j.sctalk.2022.100038</a>'
  apa: 'Clavaud, C. (2022). Shear thickening in dense suspensions: an experimental
    study. <i>Science Talks</i>. Elsevier. <a href="https://doi.org/10.1016/j.sctalk.2022.100038">https://doi.org/10.1016/j.sctalk.2022.100038</a>'
  chicago: 'Clavaud, Cécile. “Shear Thickening in Dense Suspensions: An Experimental
    Study.” <i>Science Talks</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.sctalk.2022.100038">https://doi.org/10.1016/j.sctalk.2022.100038</a>.'
  ieee: 'C. Clavaud, “Shear thickening in dense suspensions: an experimental study,”
    <i>Science Talks</i>, vol. 3. Elsevier, 2022.'
  ista: 'Clavaud C. 2022. Shear thickening in dense suspensions: an experimental study.
    Science Talks. 3, 100038.'
  mla: 'Clavaud, Cécile. “Shear Thickening in Dense Suspensions: An Experimental Study.”
    <i>Science Talks</i>, vol. 3, 100038, Elsevier, 2022, doi:<a href="https://doi.org/10.1016/j.sctalk.2022.100038">10.1016/j.sctalk.2022.100038</a>.'
  short: C. Clavaud, Science Talks 3 (2022).
corr_author: '1'
date_created: 2024-12-01T23:01:55Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2024-12-11T09:24:57Z
day: '01'
ddc:
- '530'
department:
- _id: ScWa
doi: 10.1016/j.sctalk.2022.100038
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file_date_updated: 2024-12-11T09:22:19Z
has_accepted_license: '1'
intvolume: '         3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '08'
oa: 1
oa_version: Published Version
publication: Science Talks
publication_identifier:
  eissn:
  - 2772-5693
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Shear thickening in dense suspensions: an experimental study'
tmp:
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  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2022'
...
---
_id: '12261'
abstract:
- lang: eng
  text: 'Dose–response relationships are a general concept for quantitatively describing
    biological systems across multiple scales, from the molecular to the whole-cell
    level. A clinically relevant example is the bacterial growth response to antibiotics,
    which is routinely characterized by dose–response curves. The shape of the dose–response
    curve varies drastically between antibiotics and plays a key role in treatment,
    drug interactions, and resistance evolution. However, the mechanisms shaping the
    dose–response curve remain largely unclear. Here, we show in Escherichia coli
    that the distinctively shallow dose–response curve of the antibiotic trimethoprim
    is caused by a negative growth-mediated feedback loop: Trimethoprim slows growth,
    which in turn weakens the effect of this antibiotic. At the molecular level, this
    feedback is caused by the upregulation of the drug target dihydrofolate reductase
    (FolA/DHFR). We show that this upregulation is not a specific response to trimethoprim
    but follows a universal trend line that depends primarily on the growth rate,
    irrespective of its cause. Rewiring the feedback loop alters the dose–response
    curve in a predictable manner, which we corroborate using a mathematical model
    of cellular resource allocation and growth. Our results indicate that growth-mediated
    feedback loops may shape drug responses more generally and could be exploited
    to design evolutionary traps that enable selection against drug resistance.'
acknowledged_ssus:
- _id: M-Shop
acknowledgement: This work was in part supported by Human Frontier Science Program
  GrantRGP0042/2013, Marie Curie Career Integration Grant303507, AustrianScience Fund
  (FWF) Grant P27201-B22, and German Research Foundation(DFG) Collaborative Research
  Center (SFB)1310to TB. SAA was supportedby the European Union’s Horizon2020Research
  and Innovation Programunder the Marie Skłodowska-Curie Grant agreement No707352.
  We wouldlike to thank the Bollenbach group for regular fruitful discussions. We
  areparticularly thankful for the technical assistance of Booshini Fernando andfor
  discussions of the theoretical aspects with Gerrit Ansmann. We areindebted to Bor
  Kavˇciˇc for invaluable advice, help with setting up theluciferase-based growth
  monitoring system, and for sharing plasmids. Weacknowledge the IST Austria Miba
  Machine Shop for their support inbuilding a housing for the stacker of the plate
  reader, which enabled thehigh-throughput luciferase-based experiments. We are grateful
  to RosalindAllen, Bor Kavˇciˇc and Dor Russ for feedback on the manuscript. Open
  Accessfunding enabled and organized by Projekt DEAL.
article_number: e10490
article_processing_charge: No
article_type: original
author:
- first_name: Andreas
  full_name: Angermayr, Andreas
  id: 4677C796-F248-11E8-B48F-1D18A9856A87
  last_name: Angermayr
  orcid: 0000-0001-8619-2223
- first_name: Tin Yau
  full_name: Pang, Tin Yau
  last_name: Pang
- first_name: Guillaume
  full_name: Chevereau, Guillaume
  last_name: Chevereau
- first_name: Karin
  full_name: Mitosch, Karin
  id: 39B66846-F248-11E8-B48F-1D18A9856A87
  last_name: Mitosch
- first_name: Martin J
  full_name: Lercher, Martin J
  last_name: Lercher
- first_name: Mark Tobias
  full_name: Bollenbach, Mark Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Angermayr A, Pang TY, Chevereau G, Mitosch K, Lercher MJ, Bollenbach MT. Growth‐mediated
    negative feedback shapes quantitative antibiotic response. <i>Molecular Systems
    Biology</i>. 2022;18(9). doi:<a href="https://doi.org/10.15252/msb.202110490">10.15252/msb.202110490</a>
  apa: Angermayr, A., Pang, T. Y., Chevereau, G., Mitosch, K., Lercher, M. J., &#38;
    Bollenbach, M. T. (2022). Growth‐mediated negative feedback shapes quantitative
    antibiotic response. <i>Molecular Systems Biology</i>. Embo Press. <a href="https://doi.org/10.15252/msb.202110490">https://doi.org/10.15252/msb.202110490</a>
  chicago: Angermayr, Andreas, Tin Yau Pang, Guillaume Chevereau, Karin Mitosch, Martin
    J Lercher, and Mark Tobias Bollenbach. “Growth‐mediated Negative Feedback Shapes
    Quantitative Antibiotic Response.” <i>Molecular Systems Biology</i>. Embo Press,
    2022. <a href="https://doi.org/10.15252/msb.202110490">https://doi.org/10.15252/msb.202110490</a>.
  ieee: A. Angermayr, T. Y. Pang, G. Chevereau, K. Mitosch, M. J. Lercher, and M.
    T. Bollenbach, “Growth‐mediated negative feedback shapes quantitative antibiotic
    response,” <i>Molecular Systems Biology</i>, vol. 18, no. 9. Embo Press, 2022.
  ista: Angermayr A, Pang TY, Chevereau G, Mitosch K, Lercher MJ, Bollenbach MT. 2022.
    Growth‐mediated negative feedback shapes quantitative antibiotic response. Molecular
    Systems Biology. 18(9), e10490.
  mla: Angermayr, Andreas, et al. “Growth‐mediated Negative Feedback Shapes Quantitative
    Antibiotic Response.” <i>Molecular Systems Biology</i>, vol. 18, no. 9, e10490,
    Embo Press, 2022, doi:<a href="https://doi.org/10.15252/msb.202110490">10.15252/msb.202110490</a>.
  short: A. Angermayr, T.Y. Pang, G. Chevereau, K. Mitosch, M.J. Lercher, M.T. Bollenbach,
    Molecular Systems Biology 18 (2022).
date_created: 2023-01-16T09:58:34Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-06-11T14:10:18Z
day: '01'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.15252/msb.202110490
external_id:
  isi:
  - '000856482800001'
  pmid:
  - '36124745'
file:
- access_level: open_access
  checksum: 8b1d8f5ea20c8408acf466435fb6ae01
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T09:49:55Z
  date_updated: 2023-01-30T09:49:55Z
  file_id: '12446'
  file_name: 2022_MolecularSystemsBio_Angermayr.pdf
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  relation: main_file
  success: 1
file_date_updated: 2023-01-30T09:49:55Z
has_accepted_license: '1'
intvolume: '        18'
isi: 1
issue: '9'
keyword:
- Applied Mathematics
- Computational Theory and Mathematics
- General Agricultural and Biological Sciences
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- Information Systems
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Molecular Systems Biology
publication_identifier:
  eissn:
  - 1744-4292
publication_status: published
publisher: Embo Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Growth‐mediated negative feedback shapes quantitative antibiotic response
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2022'
...
---
_id: '12262'
abstract:
- lang: eng
  text: The AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis that
    initiates cytoplasmic maturation of the large ribosomal subunit. Drg1 releases
    the shuttling maturation factor Rlp24 from pre-60S particles shortly after nuclear
    export, a strict requirement for downstream maturation. The molecular mechanism
    of release remained elusive. Here, we report a series of cryo-EM structures that
    captured the extraction of Rlp24 from pre-60S particles by Saccharomyces cerevisiae
    Drg1. These structures reveal that Arx1 and the eukaryote-specific rRNA expansion
    segment ES27 form a joint docking platform that positions Drg1 for efficient extraction
    of Rlp24 from the pre-ribosome. The tips of the Drg1 N domains thereby guide the
    Rlp24 C terminus into the central pore of the Drg1 hexamer, enabling extraction
    by a hand-over-hand translocation mechanism. Our results uncover substrate recognition
    and processing by Drg1 step by step and provide a comprehensive mechanistic picture
    of the conserved modus operandi of AAA-ATPases.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: "We thank M. Fromont-Racine, A. Johnson, J. Woolford, S. Rospert,
  J. P. G. Ballesta and\r\nE. Hurt for supplying antibodies. The work was supported
  by Boehringer Ingelheim (to\r\nD. H.), the Austrian Science Foundation FWF (grants
  32536 and 32977 to H. B.), the\r\nUK Medical Research Council (MR/T012412/1 to A.
  J. W.) and the German Research\r\nFoundation (Emmy Noether Programme STE 2517/1-1
  and STE 2517/5-1 to F.S.). We\r\nthank Norberto Escudero-Urquijo, Pablo Castro-Hartmann
  and K. Dent, Cambridge\r\nInstitute for Medical Research, for their help in cryo-EM
  during early phases of this\r\nproject. This research was supported by the Scientific
  Service Units of IST Austria through\r\nresources provided by the Electron Microscopy
  Facility. We thank S. Keller, Institute of\r\nMolecular Biosciences (Biophysics),
  University Graz for support with the quantification of\r\nthe SPR particle release
  assay. We thank I. Schaffner, University of Natural Resources and\r\nLife Sciences,
  Vienna for her help in early stages of the SPR experiments."
article_processing_charge: No
article_type: original
author:
- first_name: Michael
  full_name: Prattes, Michael
  last_name: Prattes
- first_name: Irina
  full_name: Grishkovskaya, Irina
  last_name: Grishkovskaya
- first_name: Victor-Valentin
  full_name: Hodirnau, Victor-Valentin
  id: 3661B498-F248-11E8-B48F-1D18A9856A87
  last_name: Hodirnau
- first_name: Christina
  full_name: Hetzmannseder, Christina
  last_name: Hetzmannseder
- first_name: Gertrude
  full_name: Zisser, Gertrude
  last_name: Zisser
- first_name: Carolin
  full_name: Sailer, Carolin
  last_name: Sailer
- first_name: Vasileios
  full_name: Kargas, Vasileios
  last_name: Kargas
- first_name: Mathias
  full_name: Loibl, Mathias
  last_name: Loibl
- first_name: Magdalena
  full_name: Gerhalter, Magdalena
  last_name: Gerhalter
- first_name: Lisa
  full_name: Kofler, Lisa
  last_name: Kofler
- first_name: Alan J.
  full_name: Warren, Alan J.
  last_name: Warren
- first_name: Florian
  full_name: Stengel, Florian
  last_name: Stengel
- first_name: David
  full_name: Haselbach, David
  last_name: Haselbach
- first_name: Helmut
  full_name: Bergler, Helmut
  last_name: Bergler
citation:
  ama: Prattes M, Grishkovskaya I, Hodirnau V-V, et al. Visualizing maturation factor
    extraction from the nascent ribosome by the AAA-ATPase Drg1. <i>Nature Structural
    &#38; Molecular Biology</i>. 2022;29(9):942-953. doi:<a href="https://doi.org/10.1038/s41594-022-00832-5">10.1038/s41594-022-00832-5</a>
  apa: Prattes, M., Grishkovskaya, I., Hodirnau, V.-V., Hetzmannseder, C., Zisser,
    G., Sailer, C., … Bergler, H. (2022). Visualizing maturation factor extraction
    from the nascent ribosome by the AAA-ATPase Drg1. <i>Nature Structural &#38; Molecular
    Biology</i>. Springer Nature. <a href="https://doi.org/10.1038/s41594-022-00832-5">https://doi.org/10.1038/s41594-022-00832-5</a>
  chicago: Prattes, Michael, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina
    Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, et al. “Visualizing
    Maturation Factor Extraction from the Nascent Ribosome by the AAA-ATPase Drg1.”
    <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/s41594-022-00832-5">https://doi.org/10.1038/s41594-022-00832-5</a>.
  ieee: M. Prattes <i>et al.</i>, “Visualizing maturation factor extraction from the
    nascent ribosome by the AAA-ATPase Drg1,” <i>Nature Structural &#38; Molecular
    Biology</i>, vol. 29, no. 9. Springer Nature, pp. 942–953, 2022.
  ista: Prattes M, Grishkovskaya I, Hodirnau V-V, Hetzmannseder C, Zisser G, Sailer
    C, Kargas V, Loibl M, Gerhalter M, Kofler L, Warren AJ, Stengel F, Haselbach D,
    Bergler H. 2022. Visualizing maturation factor extraction from the nascent ribosome
    by the AAA-ATPase Drg1. Nature Structural &#38; Molecular Biology. 29(9), 942–953.
  mla: Prattes, Michael, et al. “Visualizing Maturation Factor Extraction from the
    Nascent Ribosome by the AAA-ATPase Drg1.” <i>Nature Structural &#38; Molecular
    Biology</i>, vol. 29, no. 9, Springer Nature, 2022, pp. 942–53, doi:<a href="https://doi.org/10.1038/s41594-022-00832-5">10.1038/s41594-022-00832-5</a>.
  short: M. Prattes, I. Grishkovskaya, V.-V. Hodirnau, C. Hetzmannseder, G. Zisser,
    C. Sailer, V. Kargas, M. Loibl, M. Gerhalter, L. Kofler, A.J. Warren, F. Stengel,
    D. Haselbach, H. Bergler, Nature Structural &#38; Molecular Biology 29 (2022)
    942–953.
date_created: 2023-01-16T09:59:06Z
date_published: 2022-09-12T00:00:00Z
date_updated: 2023-08-04T09:52:20Z
day: '12'
ddc:
- '570'
department:
- _id: EM-Fac
doi: 10.1038/s41594-022-00832-5
external_id:
  isi:
  - '000852942100004'
  pmid:
  - '36097293'
file:
- access_level: open_access
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  date_created: 2023-01-30T10:00:04Z
  date_updated: 2023-01-30T10:00:04Z
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  file_name: 2022_NatureStrucMolecBio_Prattes.pdf
  file_size: 9935057
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T10:00:04Z
has_accepted_license: '1'
intvolume: '        29'
isi: 1
issue: '9'
keyword:
- Molecular Biology
- Structural Biology
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 942-953
pmid: 1
publication: Nature Structural & Molecular Biology
publication_identifier:
  eissn:
  - 1545-9985
  issn:
  - 1545-9993
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase
  Drg1
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 29
year: '2022'
...
---
_id: '12264'
abstract:
- lang: eng
  text: Reproductive isolation (RI) is a core concept in evolutionary biology. It
    has been the central focus of speciation research since the modern synthesis and
    is the basis by which biological species are defined. Despite this, the term is
    used in seemingly different ways, and attempts to quantify RI have used very different
    approaches. After showing that the field lacks a clear definition of the term,
    we attempt to clarify key issues, including what RI is, how it can be quantified
    in principle, and how it can be measured in practice. Following other definitions
    with a genetic focus, we propose that RI is a quantitative measure of the effect
    that genetic differences between populations have on gene flow. Specifically,
    RI compares the flow of neutral alleles in the presence of these genetic differences
    to the flow without any such differences. RI is thus greater than zero when genetic
    differences between populations reduce the flow of neutral alleles between populations.
    We show how RI can be quantified in a range of scenarios. A key conclusion is
    that RI depends strongly on circumstances—including the spatial, temporal and
    genomic context—making it difficult to compare across systems. After reviewing
    methods for estimating RI from data, we conclude that it is difficult to measure
    in practice. We discuss our findings in light of the goals of speciation research
    and encourage the use of methods for estimating RI that integrate organismal and
    genetic approaches.
acknowledgement: 'We are grateful to the participants of the ESEB satellite symposium
  ‘Understanding reproductive isolation: bridging conceptual barriers in  speciation  research’  in  2021  for  the  interesting  discussions  that  helped  us  clarify  the  thoughts  presented  in  this  article.  We  thank  Roger
  Butlin, Michael Turelli and two anonymous reviewers for their thoughtful comments
  on this manuscript. We are also very grateful to Roger Butlin and the Barton Group
  for the continued conversa-tions about RI. In addition, we thank all participants
  of the speciation survey. Part of this work was funded by the Austrian Science Fund
  FWF (grant P 32166)'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Parvathy
  full_name: Surendranadh, Parvathy
  id: 455235B8-F248-11E8-B48F-1D18A9856A87
  last_name: Surendranadh
  orcid: 0000-0001-6395-386X
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Westram AM, Stankowski S, Surendranadh P, Barton NH. What is reproductive isolation?
    <i>Journal of Evolutionary Biology</i>. 2022;35(9):1143-1164. doi:<a href="https://doi.org/10.1111/jeb.14005">10.1111/jeb.14005</a>
  apa: Westram, A. M., Stankowski, S., Surendranadh, P., &#38; Barton, N. H. (2022).
    What is reproductive isolation? <i>Journal of Evolutionary Biology</i>. Wiley.
    <a href="https://doi.org/10.1111/jeb.14005">https://doi.org/10.1111/jeb.14005</a>
  chicago: Westram, Anja M, Sean Stankowski, Parvathy Surendranadh, and Nicholas H
    Barton. “What Is Reproductive Isolation?” <i>Journal of Evolutionary Biology</i>.
    Wiley, 2022. <a href="https://doi.org/10.1111/jeb.14005">https://doi.org/10.1111/jeb.14005</a>.
  ieee: A. M. Westram, S. Stankowski, P. Surendranadh, and N. H. Barton, “What is
    reproductive isolation?,” <i>Journal of Evolutionary Biology</i>, vol. 35, no.
    9. Wiley, pp. 1143–1164, 2022.
  ista: Westram AM, Stankowski S, Surendranadh P, Barton NH. 2022. What is reproductive
    isolation? Journal of Evolutionary Biology. 35(9), 1143–1164.
  mla: Westram, Anja M., et al. “What Is Reproductive Isolation?” <i>Journal of Evolutionary
    Biology</i>, vol. 35, no. 9, Wiley, 2022, pp. 1143–64, doi:<a href="https://doi.org/10.1111/jeb.14005">10.1111/jeb.14005</a>.
  short: A.M. Westram, S. Stankowski, P. Surendranadh, N.H. Barton, Journal of Evolutionary
    Biology 35 (2022) 1143–1164.
corr_author: '1'
date_created: 2023-01-16T09:59:24Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-04-15T08:20:40Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/jeb.14005
external_id:
  isi:
  - '000849851100002'
  pmid:
  - '36063156'
file:
- access_level: open_access
  checksum: f08de57112330a7ee88d2e1b20576a1e
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  creator: dernst
  date_created: 2023-01-30T10:05:31Z
  date_updated: 2023-01-30T10:05:31Z
  file_id: '12448'
  file_name: 2022_JourEvoBiology_Westram.pdf
  file_size: 3146793
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T10:05:31Z
has_accepted_license: '1'
intvolume: '        35'
isi: 1
issue: '9'
keyword:
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1143-1164
pmid: 1
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
  grant_number: P32166
  name: Snapdragon Speciation
publication: Journal of Evolutionary Biology
publication_identifier:
  eissn:
  - 1420-9101
  issn:
  - 1010-061X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '12265'
    relation: other
    status: public
scopus_import: '1'
status: public
title: What is reproductive isolation?
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 35
year: '2022'
...
---
_id: '12265'
acknowledgement: We  are  very  grateful  to  the  authors  of  the  commentaries  for  the  interesting
  discussion and to Luke Holman for handling this set of manuscripts. Part of this
  work was funded by the Austrian Science Fund FWF (grant P 32166).
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Parvathy
  full_name: Surendranadh, Parvathy
  id: 455235B8-F248-11E8-B48F-1D18A9856A87
  last_name: Surendranadh
  orcid: 0000-0001-6395-386X
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Westram AM, Stankowski S, Surendranadh P, Barton NH. Reproductive isolation,
    speciation, and the value of disagreement: A reply to the commentaries on ‘What
    is reproductive isolation?’ <i>Journal of Evolutionary Biology</i>. 2022;35(9):1200-1205.
    doi:<a href="https://doi.org/10.1111/jeb.14082">10.1111/jeb.14082</a>'
  apa: 'Westram, A. M., Stankowski, S., Surendranadh, P., &#38; Barton, N. H. (2022).
    Reproductive isolation, speciation, and the value of disagreement: A reply to
    the commentaries on ‘What is reproductive isolation?’ <i>Journal of Evolutionary
    Biology</i>. Wiley. <a href="https://doi.org/10.1111/jeb.14082">https://doi.org/10.1111/jeb.14082</a>'
  chicago: 'Westram, Anja M, Sean Stankowski, Parvathy Surendranadh, and Nicholas
    H Barton. “Reproductive Isolation, Speciation, and the Value of Disagreement:
    A Reply to the Commentaries on ‘What Is Reproductive Isolation?’” <i>Journal of
    Evolutionary Biology</i>. Wiley, 2022. <a href="https://doi.org/10.1111/jeb.14082">https://doi.org/10.1111/jeb.14082</a>.'
  ieee: 'A. M. Westram, S. Stankowski, P. Surendranadh, and N. H. Barton, “Reproductive
    isolation, speciation, and the value of disagreement: A reply to the commentaries
    on ‘What is reproductive isolation?,’” <i>Journal of Evolutionary Biology</i>,
    vol. 35, no. 9. Wiley, pp. 1200–1205, 2022.'
  ista: 'Westram AM, Stankowski S, Surendranadh P, Barton NH. 2022. Reproductive isolation,
    speciation, and the value of disagreement: A reply to the commentaries on ‘What
    is reproductive isolation?’ Journal of Evolutionary Biology. 35(9), 1200–1205.'
  mla: 'Westram, Anja M., et al. “Reproductive Isolation, Speciation, and the Value
    of Disagreement: A Reply to the Commentaries on ‘What Is Reproductive Isolation?’”
    <i>Journal of Evolutionary Biology</i>, vol. 35, no. 9, Wiley, 2022, pp. 1200–05,
    doi:<a href="https://doi.org/10.1111/jeb.14082">10.1111/jeb.14082</a>.'
  short: A.M. Westram, S. Stankowski, P. Surendranadh, N.H. Barton, Journal of Evolutionary
    Biology 35 (2022) 1200–1205.
corr_author: '1'
date_created: 2023-01-16T09:59:37Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-04-15T08:20:40Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/jeb.14082
external_id:
  isi:
  - '000849851100009'
file:
- access_level: open_access
  checksum: 27268009e5eec030bc10667a4ac5ed4c
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T10:14:09Z
  date_updated: 2023-01-30T10:14:09Z
  file_id: '12449'
  file_name: 2022_JourEvoBiology_Westram_Response.pdf
  file_size: 349603
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T10:14:09Z
has_accepted_license: '1'
intvolume: '        35'
isi: 1
issue: '9'
keyword:
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1200-1205
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
  grant_number: P32166
  name: Snapdragon Speciation
publication: Journal of Evolutionary Biology
publication_identifier:
  eissn:
  - 1420-9101
  issn:
  - 1010-061X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '12264'
    relation: other
    status: public
scopus_import: '1'
status: public
title: 'Reproductive isolation, speciation, and the value of disagreement: A reply
  to the commentaries on ‘What is reproductive isolation?’'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 35
year: '2022'
...
---
_id: '12268'
abstract:
- lang: eng
  text: The complexity of the microenvironment effects on cell response, show accumulating
    evidence that glioblastoma (GBM) migration and invasiveness are influenced by
    the mechanical rigidity of their surroundings. The epithelial–mesenchymal transition
    (EMT) is a well-recognized driving force of the invasive behavior of cancer. However,
    the primary mechanisms of EMT initiation and progression remain unclear. We have
    previously showed that certain substrate stiffness can selectively stimulate human
    GBM U251-MG and GL15 glioblastoma cell lines motility. The present study unifies
    several known EMT mediators to uncover the reason of the regulation and response
    to these stiffnesses. Our results revealed that changing the rigidity of the mechanical
    environment tuned the response of both cell lines through change in morphological
    features, epithelial-mesenchymal markers (E-, N-Cadherin), EGFR and ROS expressions
    in an interrelated manner. Specifically, a stiffer microenvironment induced a
    mesenchymal cell shape, a more fragmented morphology, higher intracellular cytosolic
    ROS expression and lower mitochondrial ROS. Finally, we observed that cells more
    motile showed a more depolarized mitochondrial membrane potential. Unravelling
    the process that regulates GBM cells’ infiltrative behavior could provide new
    opportunities for identification of new targets and less invasive approaches for
    treatment.
acknowledgement: "The research leading to these results has received funding from
  AIRC under IG 2021 - ID. 26328 project – P.I. Cortese Barbara and AIRC under MFAG
  2015 - ID. 16803 project – “P.I. Cortese Barbara”. The authors are also grateful
  to the ”Tecnopolo per la medicina di precisione” (TecnoMed Puglia) - Regione Puglia:
  DGR n.2117 del 21/11/2018, CUP: B84I18000540002 and “Tecnopolo di Nanotecnologia
  e Fotonica per la medicina di precisione” (TECNOMED) - FISR/MIUR-CNR: delibera CIPE
  n.3449 del 7-08-2017, CUP: B83B17000010001.\r\nWe thank Dr. Francesca Pagani for
  useful technical support. We thank also Irene Iacuitto, Giovanna Loffredo and Manuela
  Marchetti for practical administrative support."
article_number: '983507'
article_processing_charge: No
article_type: original
author:
- first_name: Bernadette
  full_name: Basilico, Bernadette
  id: 36035796-5ACA-11E9-A75E-7AF2E5697425
  last_name: Basilico
  orcid: 0000-0003-1843-3173
- first_name: Ilaria Elena
  full_name: Palamà, Ilaria Elena
  last_name: Palamà
- first_name: Stefania
  full_name: D’Amone, Stefania
  last_name: D’Amone
- first_name: Clotilde
  full_name: Lauro, Clotilde
  last_name: Lauro
- first_name: Maria
  full_name: Rosito, Maria
  last_name: Rosito
- first_name: Maddalena
  full_name: Grieco, Maddalena
  last_name: Grieco
- first_name: Patrizia
  full_name: Ratano, Patrizia
  last_name: Ratano
- first_name: Federica
  full_name: Cordella, Federica
  last_name: Cordella
- first_name: Caterina
  full_name: Sanchini, Caterina
  last_name: Sanchini
- first_name: Silvia
  full_name: Di Angelantonio, Silvia
  last_name: Di Angelantonio
- first_name: Davide
  full_name: Ragozzino, Davide
  last_name: Ragozzino
- first_name: Mariafrancesca
  full_name: Cascione, Mariafrancesca
  last_name: Cascione
- first_name: Giuseppe
  full_name: Gigli, Giuseppe
  last_name: Gigli
- first_name: Barbara
  full_name: Cortese, Barbara
  last_name: Cortese
citation:
  ama: Basilico B, Palamà IE, D’Amone S, et al. Substrate stiffness effect on molecular
    crosstalk of epithelial-mesenchymal transition mediators of human glioblastoma
    cells. <i>Frontiers in Oncology</i>. 2022;12. doi:<a href="https://doi.org/10.3389/fonc.2022.983507">10.3389/fonc.2022.983507</a>
  apa: Basilico, B., Palamà, I. E., D’Amone, S., Lauro, C., Rosito, M., Grieco, M.,
    … Cortese, B. (2022). Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal
    transition mediators of human glioblastoma cells. <i>Frontiers in Oncology</i>.
    Frontiers Media. <a href="https://doi.org/10.3389/fonc.2022.983507">https://doi.org/10.3389/fonc.2022.983507</a>
  chicago: Basilico, Bernadette, Ilaria Elena Palamà, Stefania D’Amone, Clotilde Lauro,
    Maria Rosito, Maddalena Grieco, Patrizia Ratano, et al. “Substrate Stiffness Effect
    on Molecular Crosstalk of Epithelial-Mesenchymal Transition Mediators of Human
    Glioblastoma Cells.” <i>Frontiers in Oncology</i>. Frontiers Media, 2022. <a href="https://doi.org/10.3389/fonc.2022.983507">https://doi.org/10.3389/fonc.2022.983507</a>.
  ieee: B. Basilico <i>et al.</i>, “Substrate stiffness effect on molecular crosstalk
    of epithelial-mesenchymal transition mediators of human glioblastoma cells,” <i>Frontiers
    in Oncology</i>, vol. 12. Frontiers Media, 2022.
  ista: Basilico B, Palamà IE, D’Amone S, Lauro C, Rosito M, Grieco M, Ratano P, Cordella
    F, Sanchini C, Di Angelantonio S, Ragozzino D, Cascione M, Gigli G, Cortese B.
    2022. Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal
    transition mediators of human glioblastoma cells. Frontiers in Oncology. 12, 983507.
  mla: Basilico, Bernadette, et al. “Substrate Stiffness Effect on Molecular Crosstalk
    of Epithelial-Mesenchymal Transition Mediators of Human Glioblastoma Cells.” <i>Frontiers
    in Oncology</i>, vol. 12, 983507, Frontiers Media, 2022, doi:<a href="https://doi.org/10.3389/fonc.2022.983507">10.3389/fonc.2022.983507</a>.
  short: B. Basilico, I.E. Palamà, S. D’Amone, C. Lauro, M. Rosito, M. Grieco, P.
    Ratano, F. Cordella, C. Sanchini, S. Di Angelantonio, D. Ragozzino, M. Cascione,
    G. Gigli, B. Cortese, Frontiers in Oncology 12 (2022).
date_created: 2023-01-16T10:00:28Z
date_published: 2022-08-25T00:00:00Z
date_updated: 2023-08-04T09:54:16Z
day: '25'
ddc:
- '570'
department:
- _id: GaNo
doi: 10.3389/fonc.2022.983507
external_id:
  isi:
  - '000856524900001'
  pmid:
  - '36091138'
file:
- access_level: open_access
  checksum: efc7edf9f626af31853790c5b598a68c
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T10:25:21Z
  date_updated: 2023-01-30T10:25:21Z
  file_id: '12450'
  file_name: 2022_FrontiersOntology_Basilico.pdf
  file_size: 13588502
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T10:25:21Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
keyword:
- Cancer Research
- Oncology
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Frontiers in Oncology
publication_identifier:
  issn:
  - 2234-943X
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal
  transition mediators of human glioblastoma cells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2022'
...
---
_id: '12269'
abstract:
- lang: eng
  text: We study the thermalization of a small XX chain coupled to long, gapped XXZ
    leads at either side by observing the relaxation dynamics of the whole system.
    Using extensive tensor network simulations, we show that such systems, although
    not integrable, appear to show either extremely slow thermalization or even lack
    thereof since the two cannot be distinguished within the accuracy of our numerics.
    We show that the persistent oscillations observed in the spin current in the middle
    of the XX chain are related to eigenstates of the entire system located within
    the gap of the boundary chains. We find from exact diagonalization that some of
    these states remain strictly localized within the XX chain and do not hybridize
    with the rest of the system. The frequencies of the persistent oscillations determined
    by numerical simulations of dynamics match the energy differences between these
    states exactly. This has important implications for open systems, where the strongly
    interacting leads are often assumed to thermalize the central system. Our results
    suggest that, if we employ gapped systems for the leads, this assumption does
    not hold.
acknowledgement: "M.L. and T.P. acknowledge support from the European Research Council
  (ERC) through the advanced grant 694544 – OMNES and the grant P1-0402 of Slovenian
  Research Agency (ARRS). M.L. acknowledges support from the European Research Council
  (ERC) through the starting grant 850899 – NEQuM. D.R. acknowledges support from
  the Ministry of Electronics & Information Technology (MeitY), India under the grant
  for “Centre for Excellence in Quantum\r\nTechnologies” with Ref. No. 4(7)/2020-ITEA. "
article_number: '054314'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Marko
  full_name: Ljubotina, Marko
  id: F75EE9BE-5C90-11EA-905D-16643DDC885E
  last_name: Ljubotina
  orcid: 0000-0003-0038-7068
- first_name: Dibyendu
  full_name: Roy, Dibyendu
  last_name: Roy
- first_name: Tomaž
  full_name: Prosen, Tomaž
  last_name: Prosen
citation:
  ama: Ljubotina M, Roy D, Prosen T. Absence of thermalization of free systems coupled
    to gapped interacting reservoirs. <i>Physical Review B</i>. 2022;106(5). doi:<a
    href="https://doi.org/10.1103/physrevb.106.054314">10.1103/physrevb.106.054314</a>
  apa: Ljubotina, M., Roy, D., &#38; Prosen, T. (2022). Absence of thermalization
    of free systems coupled to gapped interacting reservoirs. <i>Physical Review B</i>.
    American Physical Society. <a href="https://doi.org/10.1103/physrevb.106.054314">https://doi.org/10.1103/physrevb.106.054314</a>
  chicago: Ljubotina, Marko, Dibyendu Roy, and Tomaž Prosen. “Absence of Thermalization
    of Free Systems Coupled to Gapped Interacting Reservoirs.” <i>Physical Review
    B</i>. American Physical Society, 2022. <a href="https://doi.org/10.1103/physrevb.106.054314">https://doi.org/10.1103/physrevb.106.054314</a>.
  ieee: M. Ljubotina, D. Roy, and T. Prosen, “Absence of thermalization of free systems
    coupled to gapped interacting reservoirs,” <i>Physical Review B</i>, vol. 106,
    no. 5. American Physical Society, 2022.
  ista: Ljubotina M, Roy D, Prosen T. 2022. Absence of thermalization of free systems
    coupled to gapped interacting reservoirs. Physical Review B. 106(5), 054314.
  mla: Ljubotina, Marko, et al. “Absence of Thermalization of Free Systems Coupled
    to Gapped Interacting Reservoirs.” <i>Physical Review B</i>, vol. 106, no. 5,
    054314, American Physical Society, 2022, doi:<a href="https://doi.org/10.1103/physrevb.106.054314">10.1103/physrevb.106.054314</a>.
  short: M. Ljubotina, D. Roy, T. Prosen, Physical Review B 106 (2022).
date_created: 2023-01-16T10:00:39Z
date_published: 2022-08-31T00:00:00Z
date_updated: 2025-04-14T07:52:06Z
day: '31'
department:
- _id: MaSe
doi: 10.1103/physrevb.106.054314
ec_funded: 1
external_id:
  arxiv:
  - '2106.08373'
  isi:
  - '000861332900005'
intvolume: '       106'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2106.08373
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Absence of thermalization of free systems coupled to gapped interacting reservoirs
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 106
year: '2022'
...
---
_id: '12273'
abstract:
- lang: eng
  text: We study communication in the presence of a jamming adversary where quadratic
    power constraints are imposed on the transmitter and the jammer. The jamming signal
    is allowed to be a function of the codebook, and a noncausal but noisy observation
    of the transmitted codeword. For a certain range of the noise-to-signal ratios
    (NSRs) of the transmitter and the jammer, we are able to characterize the capacity
    of this channel under deterministic encoding or stochastic encoding, i.e., with
    no common randomness between the encoder/decoder pair. For the remaining NSR regimes,
    we determine the capacity under the assumption of a small amount of common randomness
    (at most 2log(n) bits in one sub-regime, and at most Ω(n) bits in the other sub-regime)
    available to the encoder-decoder pair. Our proof techniques involve a novel myopic
    list-decoding result for achievability, and a Plotkin-type push attack for the
    converse in a subregion of the NSRs, both of which may be of independent interest.
    We also give bounds on the strong secrecy capacity of this channel assuming that
    the jammer is simultaneously eavesdropping.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yihan
  full_name: Zhang, Yihan
  id: 2ce5da42-b2ea-11eb-bba5-9f264e9d002c
  last_name: Zhang
  orcid: 0000-0002-6465-6258
- first_name: Shashank
  full_name: Vatedka, Shashank
  last_name: Vatedka
- first_name: Sidharth
  full_name: Jaggi, Sidharth
  last_name: Jaggi
- first_name: Anand D.
  full_name: Sarwate, Anand D.
  last_name: Sarwate
citation:
  ama: Zhang Y, Vatedka S, Jaggi S, Sarwate AD. Quadratically constrained myopic adversarial
    channels. <i>IEEE Transactions on Information Theory</i>. 2022;68(8):4901-4948.
    doi:<a href="https://doi.org/10.1109/tit.2022.3167554">10.1109/tit.2022.3167554</a>
  apa: Zhang, Y., Vatedka, S., Jaggi, S., &#38; Sarwate, A. D. (2022). Quadratically
    constrained myopic adversarial channels. <i>IEEE Transactions on Information Theory</i>.
    Institute of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/tit.2022.3167554">https://doi.org/10.1109/tit.2022.3167554</a>
  chicago: Zhang, Yihan, Shashank Vatedka, Sidharth Jaggi, and Anand D. Sarwate. “Quadratically
    Constrained Myopic Adversarial Channels.” <i>IEEE Transactions on Information
    Theory</i>. Institute of Electrical and Electronics Engineers, 2022. <a href="https://doi.org/10.1109/tit.2022.3167554">https://doi.org/10.1109/tit.2022.3167554</a>.
  ieee: Y. Zhang, S. Vatedka, S. Jaggi, and A. D. Sarwate, “Quadratically constrained
    myopic adversarial channels,” <i>IEEE Transactions on Information Theory</i>,
    vol. 68, no. 8. Institute of Electrical and Electronics Engineers, pp. 4901–4948,
    2022.
  ista: Zhang Y, Vatedka S, Jaggi S, Sarwate AD. 2022. Quadratically constrained myopic
    adversarial channels. IEEE Transactions on Information Theory. 68(8), 4901–4948.
  mla: Zhang, Yihan, et al. “Quadratically Constrained Myopic Adversarial Channels.”
    <i>IEEE Transactions on Information Theory</i>, vol. 68, no. 8, Institute of Electrical
    and Electronics Engineers, 2022, pp. 4901–48, doi:<a href="https://doi.org/10.1109/tit.2022.3167554">10.1109/tit.2022.3167554</a>.
  short: Y. Zhang, S. Vatedka, S. Jaggi, A.D. Sarwate, IEEE Transactions on Information
    Theory 68 (2022) 4901–4948.
corr_author: '1'
date_created: 2023-01-16T10:01:19Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2024-10-09T21:03:54Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/tit.2022.3167554
external_id:
  arxiv:
  - '1801.05951'
  isi:
  - '000838527100004'
intvolume: '        68'
isi: 1
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1801.05951
month: '08'
oa: 1
oa_version: Preprint
page: 4901-4948
publication: IEEE Transactions on Information Theory
publication_identifier:
  eissn:
  - 1557-9654
  issn:
  - 0018-9448
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quadratically constrained myopic adversarial channels
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 68
year: '2022'
...
---
_id: '12274'
abstract:
- lang: eng
  text: The morphology and functionality of the epithelial lining differ along the
    intestinal tract, but tissue renewal at all sites is driven by stem cells at the
    base of crypts1,2,3. Whether stem cell numbers and behaviour vary at different
    sites is unknown. Here we show using intravital microscopy that, despite similarities
    in the number and distribution of proliferative cells with an Lgr5 signature in
    mice, small intestinal crypts contain twice as many effective stem cells as large
    intestinal crypts. We find that, although passively displaced by a conveyor-belt-like
    upward movement, small intestinal cells positioned away from the crypt base can
    function as long-term effective stem cells owing to Wnt-dependent retrograde cellular
    movement. By contrast, the near absence of retrograde movement in the large intestine
    restricts cell repositioning, leading to a reduction in effective stem cell number.
    Moreover, after suppression of the retrograde movement in the small intestine,
    the number of effective stem cells is reduced, and the rate of monoclonal conversion
    of crypts is accelerated. Together, these results show that the number of effective
    stem cells is determined by active retrograde movement, revealing a new channel
    of stem cell regulation that can be experimentally and pharmacologically manipulated.
acknowledgement: We thank the members of the van Rheenen laboratory for reading the
  manuscript, and the members of the bioimaging, FACS and animal facility of the NKI
  for experimental support. We acknowledge the staff at the MedH Flow Cytometry core
  facility, Karolinska Institutet, and LCI facility/Nikon Center of Excellence, Karolinska
  Institutet. This work was financially supported by the Netherlands Organization
  of Scientific Research NWO (Veni grant 863.15.011 to S.I.J.E. and Vici grant 09150182110004
  to J.v.R.) and the CancerGenomics.nl (Netherlands Organisation for Scientific Research)
  program (to J.v.R.) the Doctor Josef Steiner Foundation (to J.v.R). B.D.S. acknowledges
  funding from the Royal Society E.P. Abraham Research Professorship (RP\R1\180165)
  and the Wellcome Trust (098357/Z/12/Z and 219478/Z/19/Z). B.C.-M. acknowledges the
  support of the field of excellence ‘Complexity of life in basic research and innovation’
  of the University of Graz. O.J.S. and their laboratory acknowledge CRUK core funding
  to the CRUK Beatson Institute (A17196 and A31287) and CRUK core funding to the Sansom
  laboratory (A21139). P.K. and their laboratory are supported by grants from the
  Swedish Research Council (2018-03078), Cancerfonden (190634), Academy of Finland
  Centre of Excellence (266869, 304591 and 320185) and the Jane and Aatos Erkko Foundation.
  P.L. has received funding from the European Research Council (ERC) under the European
  Union’s Horizon 2020 research and innovation programme (grant agreement no. 758617).
  E.H. acknowledges funding from the European Research Council (ERC) under the European
  Union’s Horizon 2020 research and innovation programme (grant agreement no. 851288).
article_processing_charge: No
article_type: original
author:
- first_name: Maria
  full_name: Azkanaz, Maria
  last_name: Azkanaz
- first_name: Bernat
  full_name: Corominas-Murtra, Bernat
  id: 43BE2298-F248-11E8-B48F-1D18A9856A87
  last_name: Corominas-Murtra
  orcid: 0000-0001-9806-5643
- first_name: Saskia I. J.
  full_name: Ellenbroek, Saskia I. J.
  last_name: Ellenbroek
- first_name: Lotte
  full_name: Bruens, Lotte
  last_name: Bruens
- first_name: Anna T.
  full_name: Webb, Anna T.
  last_name: Webb
- first_name: Dimitrios
  full_name: Laskaris, Dimitrios
  last_name: Laskaris
- first_name: Koen C.
  full_name: Oost, Koen C.
  last_name: Oost
- first_name: Simona J. A.
  full_name: Lafirenze, Simona J. A.
  last_name: Lafirenze
- first_name: Karl
  full_name: Annusver, Karl
  last_name: Annusver
- first_name: Hendrik A.
  full_name: Messal, Hendrik A.
  last_name: Messal
- first_name: Sharif
  full_name: Iqbal, Sharif
  last_name: Iqbal
- first_name: Dustin J.
  full_name: Flanagan, Dustin J.
  last_name: Flanagan
- first_name: David J.
  full_name: Huels, David J.
  last_name: Huels
- first_name: Felipe
  full_name: Rojas-Rodríguez, Felipe
  last_name: Rojas-Rodríguez
- first_name: Miguel
  full_name: Vizoso, Miguel
  last_name: Vizoso
- first_name: Maria
  full_name: Kasper, Maria
  last_name: Kasper
- first_name: Owen J.
  full_name: Sansom, Owen J.
  last_name: Sansom
- first_name: Hugo J.
  full_name: Snippert, Hugo J.
  last_name: Snippert
- first_name: Prisca
  full_name: Liberali, Prisca
  last_name: Liberali
- first_name: Benjamin D.
  full_name: Simons, Benjamin D.
  last_name: Simons
- first_name: Pekka
  full_name: Katajisto, Pekka
  last_name: Katajisto
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Jacco
  full_name: van Rheenen, Jacco
  last_name: van Rheenen
citation:
  ama: Azkanaz M, Corominas-Murtra B, Ellenbroek SIJ, et al. Retrograde movements
    determine effective stem cell numbers in the intestine. <i>Nature</i>. 2022;607(7919):548-554.
    doi:<a href="https://doi.org/10.1038/s41586-022-04962-0">10.1038/s41586-022-04962-0</a>
  apa: Azkanaz, M., Corominas-Murtra, B., Ellenbroek, S. I. J., Bruens, L., Webb,
    A. T., Laskaris, D., … van Rheenen, J. (2022). Retrograde movements determine
    effective stem cell numbers in the intestine. <i>Nature</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41586-022-04962-0">https://doi.org/10.1038/s41586-022-04962-0</a>
  chicago: Azkanaz, Maria, Bernat Corominas-Murtra, Saskia I. J. Ellenbroek, Lotte
    Bruens, Anna T. Webb, Dimitrios Laskaris, Koen C. Oost, et al. “Retrograde Movements
    Determine Effective Stem Cell Numbers in the Intestine.” <i>Nature</i>. Springer
    Nature, 2022. <a href="https://doi.org/10.1038/s41586-022-04962-0">https://doi.org/10.1038/s41586-022-04962-0</a>.
  ieee: M. Azkanaz <i>et al.</i>, “Retrograde movements determine effective stem cell
    numbers in the intestine,” <i>Nature</i>, vol. 607, no. 7919. Springer Nature,
    pp. 548–554, 2022.
  ista: Azkanaz M, Corominas-Murtra B, Ellenbroek SIJ, Bruens L, Webb AT, Laskaris
    D, Oost KC, Lafirenze SJA, Annusver K, Messal HA, Iqbal S, Flanagan DJ, Huels
    DJ, Rojas-Rodríguez F, Vizoso M, Kasper M, Sansom OJ, Snippert HJ, Liberali P,
    Simons BD, Katajisto P, Hannezo EB, van Rheenen J. 2022. Retrograde movements
    determine effective stem cell numbers in the intestine. Nature. 607(7919), 548–554.
  mla: Azkanaz, Maria, et al. “Retrograde Movements Determine Effective Stem Cell
    Numbers in the Intestine.” <i>Nature</i>, vol. 607, no. 7919, Springer Nature,
    2022, pp. 548–54, doi:<a href="https://doi.org/10.1038/s41586-022-04962-0">10.1038/s41586-022-04962-0</a>.
  short: M. Azkanaz, B. Corominas-Murtra, S.I.J. Ellenbroek, L. Bruens, A.T. Webb,
    D. Laskaris, K.C. Oost, S.J.A. Lafirenze, K. Annusver, H.A. Messal, S. Iqbal,
    D.J. Flanagan, D.J. Huels, F. Rojas-Rodríguez, M. Vizoso, M. Kasper, O.J. Sansom,
    H.J. Snippert, P. Liberali, B.D. Simons, P. Katajisto, E.B. Hannezo, J. van Rheenen,
    Nature 607 (2022) 548–554.
corr_author: '1'
date_created: 2023-01-16T10:01:29Z
date_published: 2022-07-13T00:00:00Z
date_updated: 2025-04-14T07:52:27Z
day: '13'
department:
- _id: EdHa
doi: 10.1038/s41586-022-04962-0
ec_funded: 1
external_id:
  isi:
  - '000824430000004'
  pmid:
  - '35831497'
intvolume: '       607'
isi: 1
issue: '7919'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://helda.helsinki.fi/items/94433455-4854-45c0-9de8-7326caea8780
month: '07'
oa: 1
oa_version: Submitted Version
page: 548-554
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/JaccovanRheenenLab/Retrograde_movement_Azkanaz_Nature_2022
scopus_import: '1'
status: public
title: Retrograde movements determine effective stem cell numbers in the intestine
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 607
year: '2022'
...
---
_id: '12275'
abstract:
- lang: eng
  text: N-glycans are molecularly diverse sugars borne by over 70% of proteins transiting
    the secretory pathway and have been implicated in protein folding, stability,
    and localization. Mutations in genes important for N-glycosylation result in congenital
    disorders of glycosylation that are often associated with intellectual disability.
    Here, we show that structurally distinct N-glycans regulate an extracellular protein
    complex involved in the patterning of somatosensory dendrites in Caenorhabditis
    elegans. Specifically, aman-2/Golgi alpha-mannosidase II, a conserved key enzyme
    in the biosynthesis of specific N-glycans, regulates the activity of the Menorin
    adhesion complex without obviously affecting the protein stability and localization
    of its components. AMAN-2 functions cell-autonomously to allow for decoration
    of the neuronal transmembrane receptor DMA-1/LRR-TM with the correct set of high-mannose/hybrid/paucimannose
    N-glycans. Moreover, distinct types of N-glycans on specific N-glycosylation sites
    regulate DMA-1/LRR-TM receptor function, which, together with three other extracellular
    proteins, forms the Menorin adhesion complex. In summary, specific N-glycan structures
    regulate dendrite patterning by coordinating the activity of an extracellular
    adhesion complex, suggesting that the molecular diversity of N-glycans can contribute
    to developmental specificity in the nervous system.
acknowledgement: 'We thank Scott Garforth, Sarah Garrett, Peri Kurshan, Yehuda Salzberg,
  PamelaStanley, Robert Townley, and members of the B€ulow laboratory for commentson
  the manuscript or helpful discussions during the course of this work. Wethank David
  Miller, Shohei Mitani, Kang Shen, and Iain Wilson for reagents,and Yuji Kohara for
  theyk11g705cDNA clone. We are grateful to MeeraTrivedi for sharing thedzIs117strain
  prior to publication. Some strains wereprovided by the Caenorhabditis Genome Center
  (funded by the NIH Office ofResearch Infrastructure Programs P40OD010440). This
  work was supportedby grants from the National Institute of Health (NIH): R01NS096672andR21NS111145to
  HEB; F31NS100370to MR; T32GM007288and F31HD066967to CADB; P30HD071593to Albert Einstein
  College of Medicine. We acknowl-edge support to MR by the Department of Neuroscience.
  NJRS was the recipi-ent of a Colciencias-Fulbright Fellowship and HEB of an Irma
  T. Hirschl/Monique Weill-Caulier research fellowship'
article_number: e54163
article_processing_charge: No
article_type: original
author:
- first_name: Maisha
  full_name: Rahman, Maisha
  last_name: Rahman
- first_name: Nelson
  full_name: Ramirez, Nelson
  id: 39831956-E4FE-11E9-85DE-0DC7E5697425
  last_name: Ramirez
- first_name: Carlos A
  full_name: Diaz‐Balzac, Carlos A
  last_name: Diaz‐Balzac
- first_name: Hannes E
  full_name: Bülow, Hannes E
  last_name: Bülow
citation:
  ama: Rahman M, Ramirez N, Diaz‐Balzac CA, Bülow HE. Specific N-glycans regulate
    an extracellular adhesion complex during somatosensory dendrite patterning. <i>EMBO
    Reports</i>. 2022;23(7). doi:<a href="https://doi.org/10.15252/embr.202154163">10.15252/embr.202154163</a>
  apa: Rahman, M., Ramirez, N., Diaz‐Balzac, C. A., &#38; Bülow, H. E. (2022). Specific
    N-glycans regulate an extracellular adhesion complex during somatosensory dendrite
    patterning. <i>EMBO Reports</i>. Embo Press. <a href="https://doi.org/10.15252/embr.202154163">https://doi.org/10.15252/embr.202154163</a>
  chicago: Rahman, Maisha, Nelson Ramirez, Carlos A Diaz‐Balzac, and Hannes E Bülow.
    “Specific N-Glycans Regulate an Extracellular Adhesion Complex during Somatosensory
    Dendrite Patterning.” <i>EMBO Reports</i>. Embo Press, 2022. <a href="https://doi.org/10.15252/embr.202154163">https://doi.org/10.15252/embr.202154163</a>.
  ieee: M. Rahman, N. Ramirez, C. A. Diaz‐Balzac, and H. E. Bülow, “Specific N-glycans
    regulate an extracellular adhesion complex during somatosensory dendrite patterning,”
    <i>EMBO Reports</i>, vol. 23, no. 7. Embo Press, 2022.
  ista: Rahman M, Ramirez N, Diaz‐Balzac CA, Bülow HE. 2022. Specific N-glycans regulate
    an extracellular adhesion complex during somatosensory dendrite patterning. EMBO
    Reports. 23(7), e54163.
  mla: Rahman, Maisha, et al. “Specific N-Glycans Regulate an Extracellular Adhesion
    Complex during Somatosensory Dendrite Patterning.” <i>EMBO Reports</i>, vol. 23,
    no. 7, e54163, Embo Press, 2022, doi:<a href="https://doi.org/10.15252/embr.202154163">10.15252/embr.202154163</a>.
  short: M. Rahman, N. Ramirez, C.A. Diaz‐Balzac, H.E. Bülow, EMBO Reports 23 (2022).
date_created: 2023-01-16T10:01:44Z
date_published: 2022-07-05T00:00:00Z
date_updated: 2023-10-03T11:25:54Z
day: '05'
department:
- _id: MaDe
doi: 10.15252/embr.202154163
external_id:
  isi:
  - '000797302700001'
  pmid:
  - '35586945'
has_accepted_license: '1'
intvolume: '        23'
isi: 1
issue: '7'
keyword:
- Genetics
- Molecular Biology
- Biochemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.15252/embr.202154163
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: EMBO Reports
publication_identifier:
  eissn:
  - 1469-3178
  issn:
  - 1469-221X
publication_status: published
publisher: Embo Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Specific N-glycans regulate an extracellular adhesion complex during somatosensory
  dendrite patterning
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2022'
...
---
_id: '12276'
abstract:
- lang: eng
  text: Ongoing development of quantum simulators allows for a progressively finer
    degree of control of quantum many-body systems. This motivates the development
    of efficient approaches to facilitate the control of such systems and enable the
    preparation of nontrivial quantum states. Here we formulate an approach to control
    quantum systems based on matrix product states (MPSs). We compare counterdiabatic
    and leakage minimization approaches to the so-called local steering problem that
    consists in finding the best value of the control parameters for generating a
    unitary evolution of the specific MPS in a given direction. In order to benchmark
    the different approaches, we apply them to the generalization of the PXP model
    known to exhibit coherent quantum dynamics due to quantum many-body scars. We
    find that the leakage-based approach generally outperforms the counterdiabatic
    framework and use it to construct a Floquet model with quantum scars. We perform
    the first steps towards global trajectory optimization and demonstrate entanglement
    steering capabilities in the generalized PXP model. Finally, we apply our leakage
    minimization approach to construct quantum scars in the periodically driven nonintegrable
    Ising model.
acknowledgement: We thank A. A. Michailidis for insightful discussions. M.L. and M.S.
  acknowledge support from the European Research Council (ERC) under the European
  Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 850899).
  D.A. is supported by the European Research Council (ERC) under the European Union’s
  Horizon 2020 research and innovation programme (Grant Agreement No. 864597) and
  by the Swiss National Science Foundation. The infinite TEBD simulations were performed
  using the ITensor library [67].
article_number: '030343'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Marko
  full_name: Ljubotina, Marko
  id: F75EE9BE-5C90-11EA-905D-16643DDC885E
  last_name: Ljubotina
  orcid: 0000-0003-0038-7068
- first_name: Barbara
  full_name: Roos, Barbara
  id: 5DA90512-D80F-11E9-8994-2E2EE6697425
  last_name: Roos
  orcid: 0000-0002-9071-5880
- first_name: Dmitry A.
  full_name: Abanin, Dmitry A.
  last_name: Abanin
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: Ljubotina M, Roos B, Abanin DA, Serbyn M. Optimal steering of matrix product
    states and quantum many-body scars. <i>PRX Quantum</i>. 2022;3(3). doi:<a href="https://doi.org/10.1103/prxquantum.3.030343">10.1103/prxquantum.3.030343</a>
  apa: Ljubotina, M., Roos, B., Abanin, D. A., &#38; Serbyn, M. (2022). Optimal steering
    of matrix product states and quantum many-body scars. <i>PRX Quantum</i>. American
    Physical Society. <a href="https://doi.org/10.1103/prxquantum.3.030343">https://doi.org/10.1103/prxquantum.3.030343</a>
  chicago: Ljubotina, Marko, Barbara Roos, Dmitry A. Abanin, and Maksym Serbyn. “Optimal
    Steering of Matrix Product States and Quantum Many-Body Scars.” <i>PRX Quantum</i>.
    American Physical Society, 2022. <a href="https://doi.org/10.1103/prxquantum.3.030343">https://doi.org/10.1103/prxquantum.3.030343</a>.
  ieee: M. Ljubotina, B. Roos, D. A. Abanin, and M. Serbyn, “Optimal steering of matrix
    product states and quantum many-body scars,” <i>PRX Quantum</i>, vol. 3, no. 3.
    American Physical Society, 2022.
  ista: Ljubotina M, Roos B, Abanin DA, Serbyn M. 2022. Optimal steering of matrix
    product states and quantum many-body scars. PRX Quantum. 3(3), 030343.
  mla: Ljubotina, Marko, et al. “Optimal Steering of Matrix Product States and Quantum
    Many-Body Scars.” <i>PRX Quantum</i>, vol. 3, no. 3, 030343, American Physical
    Society, 2022, doi:<a href="https://doi.org/10.1103/prxquantum.3.030343">10.1103/prxquantum.3.030343</a>.
  short: M. Ljubotina, B. Roos, D.A. Abanin, M. Serbyn, PRX Quantum 3 (2022).
corr_author: '1'
date_created: 2023-01-16T10:01:56Z
date_published: 2022-09-23T00:00:00Z
date_updated: 2025-04-14T07:52:07Z
day: '23'
ddc:
- '530'
department:
- _id: MaSe
- _id: RoSe
doi: 10.1103/prxquantum.3.030343
ec_funded: 1
external_id:
  arxiv:
  - '2204.02899'
file:
- access_level: open_access
  checksum: ef8f0a1b5a019b3958009162de0fa4c3
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T11:02:50Z
  date_updated: 2023-01-30T11:02:50Z
  file_id: '12457'
  file_name: 2022_PRXQuantum_Ljubotina.pdf
  file_size: 7661905
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T11:02:50Z
has_accepted_license: '1'
intvolume: '         3'
issue: '3'
keyword:
- General Medicine
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: PRX Quantum
publication_identifier:
  eissn:
  - 2691-3399
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal steering of matrix product states and quantum many-body scars
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2022'
...
---
_id: '12277'
abstract:
- lang: eng
  text: Cell migration in confining physiological environments relies on the concerted
    dynamics of several cellular components, including protrusions, adhesions with
    the environment, and the cell nucleus. However, it remains poorly understood how
    the dynamic interplay of these components and the cell polarity determine the
    emergent migration behavior at the cellular scale. Here, we combine data-driven
    inference with a mechanistic bottom-up approach to develop a model for protrusion
    and polarity dynamics in confined cell migration, revealing how the cellular dynamics
    adapt to confining geometries. Specifically, we use experimental data of joint
    protrusion-nucleus migration trajectories of cells on confining micropatterns
    to systematically determine a mechanistic model linking the stochastic dynamics
    of cell polarity, protrusions, and nucleus. This model indicates that the cellular
    dynamics adapt to confining constrictions through a switch in the polarity dynamics
    from a negative to a positive self-reinforcing feedback loop. Our model further
    reveals how this feedback loop leads to stereotypical cycles of protrusion-nucleus
    dynamics that drive the migration of the cell through constrictions. These cycles
    are disrupted upon perturbation of cytoskeletal components, indicating that the
    positive feedback is controlled by cellular migration mechanisms. Our data-driven
    theoretical approach therefore identifies polarity feedback adaptation as a key
    mechanism in confined cell migration.
acknowledgement: "We thank Grzegorz Gradziuk, StevenRiedijk, Janni Harju, and M. R.
  Schnucki for helpful discussions, and Andriy Goychuk for advice on the image segmentation.
  This project\r\nwas funded by the Deutsche Forschungsgemeinschaft (DFG, German Research
  Foundation), Project No. 201269156—SFB 1032 (Projects B01 and B12). D. B. B. is
  supported by the NOMIS Foundation and in part by a DFG fellowship within the Graduate
  School of Quantitative Biosciences Munich (QBM), as well as by the Joachim Herz
  Stiftung."
article_number: '031041'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: David
  full_name: Brückner, David
  id: e1e86031-6537-11eb-953a-f7ab92be508d
  last_name: Brückner
  orcid: 0000-0001-7205-2975
- first_name: Matthew
  full_name: Schmitt, Matthew
  last_name: Schmitt
- first_name: Alexandra
  full_name: Fink, Alexandra
  last_name: Fink
- first_name: Georg
  full_name: Ladurner, Georg
  last_name: Ladurner
- first_name: Johannes
  full_name: Flommersfeld, Johannes
  last_name: Flommersfeld
- first_name: Nicolas
  full_name: Arlt, Nicolas
  last_name: Arlt
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Joachim O.
  full_name: Rädler, Joachim O.
  last_name: Rädler
- first_name: Chase P.
  full_name: Broedersz, Chase P.
  last_name: Broedersz
citation:
  ama: Brückner D, Schmitt M, Fink A, et al. Geometry adaptation of protrusion and
    polarity dynamics in confined cell migration. <i>Physical Review X</i>. 2022;12(3).
    doi:<a href="https://doi.org/10.1103/physrevx.12.031041">10.1103/physrevx.12.031041</a>
  apa: Brückner, D., Schmitt, M., Fink, A., Ladurner, G., Flommersfeld, J., Arlt,
    N., … Broedersz, C. P. (2022). Geometry adaptation of protrusion and polarity
    dynamics in confined cell migration. <i>Physical Review X</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevx.12.031041">https://doi.org/10.1103/physrevx.12.031041</a>
  chicago: Brückner, David, Matthew Schmitt, Alexandra Fink, Georg Ladurner, Johannes
    Flommersfeld, Nicolas Arlt, Edouard B Hannezo, Joachim O. Rädler, and Chase P.
    Broedersz. “Geometry Adaptation of Protrusion and Polarity Dynamics in Confined
    Cell Migration.” <i>Physical Review X</i>. American Physical Society, 2022. <a
    href="https://doi.org/10.1103/physrevx.12.031041">https://doi.org/10.1103/physrevx.12.031041</a>.
  ieee: D. Brückner <i>et al.</i>, “Geometry adaptation of protrusion and polarity
    dynamics in confined cell migration,” <i>Physical Review X</i>, vol. 12, no. 3.
    American Physical Society, 2022.
  ista: Brückner D, Schmitt M, Fink A, Ladurner G, Flommersfeld J, Arlt N, Hannezo
    EB, Rädler JO, Broedersz CP. 2022. Geometry adaptation of protrusion and polarity
    dynamics in confined cell migration. Physical Review X. 12(3), 031041.
  mla: Brückner, David, et al. “Geometry Adaptation of Protrusion and Polarity Dynamics
    in Confined Cell Migration.” <i>Physical Review X</i>, vol. 12, no. 3, 031041,
    American Physical Society, 2022, doi:<a href="https://doi.org/10.1103/physrevx.12.031041">10.1103/physrevx.12.031041</a>.
  short: D. Brückner, M. Schmitt, A. Fink, G. Ladurner, J. Flommersfeld, N. Arlt,
    E.B. Hannezo, J.O. Rädler, C.P. Broedersz, Physical Review X 12 (2022).
date_created: 2023-01-16T10:02:06Z
date_published: 2022-09-20T00:00:00Z
date_updated: 2023-08-04T10:25:49Z
day: '20'
ddc:
- '530'
- '570'
department:
- _id: EdHa
doi: 10.1103/physrevx.12.031041
external_id:
  arxiv:
  - '2106.01014'
  isi:
  - '000861534700001'
file:
- access_level: open_access
  checksum: 40a8fbc3663bf07b37cb80020974d40d
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T11:07:27Z
  date_updated: 2023-01-30T11:07:27Z
  file_id: '12458'
  file_name: 2022_PhysicalReviewX_Brueckner.pdf
  file_size: 4686804
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T11:07:27Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '3'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Physical Review X
publication_identifier:
  issn:
  - 2160-3308
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Geometry adaptation of protrusion and polarity dynamics in confined cell migration
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2022'
...
---
_id: '12278'
abstract:
- lang: eng
  text: Mercury telluride (HgTe) thin films with a critical thickness of 6.5 nm are
    predicted to possess a gapless Dirac-like band structure. We report a comprehensive
    study on gated and optically doped samples by magnetooptical spectroscopy in the
    THz range. The quasi-classical analysis of the cyclotron resonance allowed the
    mapping of the band dispersion of Dirac charge carriers in a broad range of electron
    and hole doping. A smooth transition through the charge neutrality point between
    Dirac holes and electrons was observed. An additional peak coming from a second
    type of holes with an almost density-independent mass of around 0.04m0 was detected
    in the hole-doping range and attributed to an asymmetric spin splitting of the
    Dirac cone. Spectroscopic evidence for disorder-induced band energy fluctuations
    could not be detected in present cyclotron resonance experiments.
acknowledgement: "This work was supported by the Austrian Science Funds (W1243, I
  3456-N27, I 5539-N).\r\nOpen Access Funding by the Austrian Science Fund (FWF)."
article_number: '2492'
article_processing_charge: Yes
article_type: original
author:
- first_name: Alexey
  full_name: Shuvaev, Alexey
  last_name: Shuvaev
- first_name: Uladzislau
  full_name: Dziom, Uladzislau
  id: 6A9A37C2-8C5C-11E9-AE53-F2FDE5697425
  last_name: Dziom
  orcid: 0000-0002-1648-0999
- first_name: Jan
  full_name: Gospodarič, Jan
  last_name: Gospodarič
- first_name: Elena G.
  full_name: Novik, Elena G.
  last_name: Novik
- first_name: Alena A.
  full_name: Dobretsova, Alena A.
  last_name: Dobretsova
- first_name: Nikolay N.
  full_name: Mikhailov, Nikolay N.
  last_name: Mikhailov
- first_name: Ze Don
  full_name: Kvon, Ze Don
  last_name: Kvon
- first_name: Andrei
  full_name: Pimenov, Andrei
  last_name: Pimenov
citation:
  ama: Shuvaev A, Dziom V, Gospodarič J, et al. Band structure near the Dirac Point
    in HgTe quantum wells with critical thickness. <i>Nanomaterials</i>. 2022;12(14).
    doi:<a href="https://doi.org/10.3390/nano12142492">10.3390/nano12142492</a>
  apa: Shuvaev, A., Dziom, V., Gospodarič, J., Novik, E. G., Dobretsova, A. A., Mikhailov,
    N. N., … Pimenov, A. (2022). Band structure near the Dirac Point in HgTe quantum
    wells with critical thickness. <i>Nanomaterials</i>. MDPI. <a href="https://doi.org/10.3390/nano12142492">https://doi.org/10.3390/nano12142492</a>
  chicago: Shuvaev, Alexey, Vlad Dziom, Jan Gospodarič, Elena G. Novik, Alena A. Dobretsova,
    Nikolay N. Mikhailov, Ze Don Kvon, and Andrei Pimenov. “Band Structure near the
    Dirac Point in HgTe Quantum Wells with Critical Thickness.” <i>Nanomaterials</i>.
    MDPI, 2022. <a href="https://doi.org/10.3390/nano12142492">https://doi.org/10.3390/nano12142492</a>.
  ieee: A. Shuvaev <i>et al.</i>, “Band structure near the Dirac Point in HgTe quantum
    wells with critical thickness,” <i>Nanomaterials</i>, vol. 12, no. 14. MDPI, 2022.
  ista: Shuvaev A, Dziom V, Gospodarič J, Novik EG, Dobretsova AA, Mikhailov NN, Kvon
    ZD, Pimenov A. 2022. Band structure near the Dirac Point in HgTe quantum wells
    with critical thickness. Nanomaterials. 12(14), 2492.
  mla: Shuvaev, Alexey, et al. “Band Structure near the Dirac Point in HgTe Quantum
    Wells with Critical Thickness.” <i>Nanomaterials</i>, vol. 12, no. 14, 2492, MDPI,
    2022, doi:<a href="https://doi.org/10.3390/nano12142492">10.3390/nano12142492</a>.
  short: A. Shuvaev, V. Dziom, J. Gospodarič, E.G. Novik, A.A. Dobretsova, N.N. Mikhailov,
    Z.D. Kvon, A. Pimenov, Nanomaterials 12 (2022).
date_created: 2023-01-16T10:02:31Z
date_published: 2022-07-20T00:00:00Z
date_updated: 2025-06-11T13:45:36Z
day: '20'
ddc:
- '530'
department:
- _id: ZhAl
doi: 10.3390/nano12142492
external_id:
  isi:
  - '000834401600001'
  pmid:
  - '35889716'
file:
- access_level: open_access
  checksum: efad6742f89f39a18bec63116dd689a0
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T11:16:54Z
  date_updated: 2023-01-30T11:16:54Z
  file_id: '12459'
  file_name: 2022_Nanomaterials_Shuvaev.pdf
  file_size: 464840
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T11:16:54Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '14'
keyword:
- General Materials Science
- General Chemical Engineering
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nanomaterials
publication_identifier:
  issn:
  - 2079-4991
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Band structure near the Dirac Point in HgTe quantum wells with critical thickness
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2022'
...
---
_id: '12279'
abstract:
- lang: eng
  text: We report frictional drag reduction and a complete flow relaminarization of
    elastic turbulence (ET) at vanishing inertia in a viscoelastic channel flow past
    an obstacle. We show that the intensity of the observed elastic waves and wall-normal
    vorticity correlate well with the measured drag above the onset of ET. Moreover,
    we find that the elastic wave frequency grows with the Weissenberg number, and
    at sufficiently high frequency it causes a decay of the elastic waves, resulting
    in ET attenuation and drag reduction. Thus, this allows us to substantiate a physical
    mechanism, involving the interaction of elastic waves with wall-normal vorticity
    fluctuations, leading to the drag reduction and relaminarization phenomena at
    low Reynolds number.
acknowledgement: "We thank G. Falkovich for discussion and Guy Han for technical support.
  We are grateful to N. Jha for his help in µPIV measurements. This work is partially
  supported by the grants from\r\nIsrael Science Foundation (ISF; grant #882/15 and
  grant #784/19) and Binational USA-Israel Foundation (BSF;grant #2016145). "
article_number: L081301
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: M. Vijay
  full_name: Kumar, M. Vijay
  last_name: Kumar
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Dongyang
  full_name: Li, Dongyang
  last_name: Li
- first_name: Victor
  full_name: Steinberg, Victor
  last_name: Steinberg
citation:
  ama: Kumar MV, Varshney A, Li D, Steinberg V. Relaminarization of elastic turbulence.
    <i>Physical Review Fluids</i>. 2022;7(8). doi:<a href="https://doi.org/10.1103/physrevfluids.7.l081301">10.1103/physrevfluids.7.l081301</a>
  apa: Kumar, M. V., Varshney, A., Li, D., &#38; Steinberg, V. (2022). Relaminarization
    of elastic turbulence. <i>Physical Review Fluids</i>. American Physical Society.
    <a href="https://doi.org/10.1103/physrevfluids.7.l081301">https://doi.org/10.1103/physrevfluids.7.l081301</a>
  chicago: Kumar, M. Vijay, Atul Varshney, Dongyang Li, and Victor Steinberg. “Relaminarization
    of Elastic Turbulence.” <i>Physical Review Fluids</i>. American Physical Society,
    2022. <a href="https://doi.org/10.1103/physrevfluids.7.l081301">https://doi.org/10.1103/physrevfluids.7.l081301</a>.
  ieee: M. V. Kumar, A. Varshney, D. Li, and V. Steinberg, “Relaminarization of elastic
    turbulence,” <i>Physical Review Fluids</i>, vol. 7, no. 8. American Physical Society,
    2022.
  ista: Kumar MV, Varshney A, Li D, Steinberg V. 2022. Relaminarization of elastic
    turbulence. Physical Review Fluids. 7(8), L081301.
  mla: Kumar, M. Vijay, et al. “Relaminarization of Elastic Turbulence.” <i>Physical
    Review Fluids</i>, vol. 7, no. 8, L081301, American Physical Society, 2022, doi:<a
    href="https://doi.org/10.1103/physrevfluids.7.l081301">10.1103/physrevfluids.7.l081301</a>.
  short: M.V. Kumar, A. Varshney, D. Li, V. Steinberg, Physical Review Fluids 7 (2022).
corr_author: '1'
date_created: 2023-01-16T10:02:40Z
date_published: 2022-08-03T00:00:00Z
date_updated: 2024-10-09T21:03:55Z
day: '03'
department:
- _id: BjHo
doi: 10.1103/physrevfluids.7.l081301
external_id:
  arxiv:
  - '2205.12871'
  isi:
  - '000836397000001'
intvolume: '         7'
isi: 1
issue: '8'
keyword:
- Fluid Flow and Transfer Processes
- Modeling and Simulation
- Computational Mechanics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2205.12871'
month: '08'
oa: 1
oa_version: Preprint
publication: Physical Review Fluids
publication_identifier:
  issn:
  - 2469-990X
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Relaminarization of elastic turbulence
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2022'
...
---
_id: '12280'
abstract:
- lang: eng
  text: 'In repeated interactions, players can use strategies that respond to the
    outcome of previous rounds. Much of the existing literature on direct reciprocity
    assumes that all competing individuals use the same strategy space. Here, we study
    both learning and evolutionary dynamics of players that differ in the strategy
    space they explore. We focus on the infinitely repeated donation game and compare
    three natural strategy spaces: memory-1 strategies, which consider the last moves
    of both players, reactive strategies, which respond to the last move of the co-player,
    and unconditional strategies. These three strategy spaces differ in the memory
    capacity that is needed. We compute the long term average payoff that is achieved
    in a pairwise learning process. We find that smaller strategy spaces can dominate
    larger ones. For weak selection, unconditional players dominate both reactive
    and memory-1 players. For intermediate selection, reactive players dominate memory-1
    players. Only for strong selection and low cost-to-benefit ratio, memory-1 players
    dominate the others. We observe that the supergame between strategy spaces can
    be a social dilemma: maximum payoff is achieved if both players explore a larger
    strategy space, but smaller strategy spaces dominate.'
acknowledgement: "This work was supported by the European Research Council (https://erc.europa.eu/)\r\nCoG
  863818 (ForM-SMArt) (to K.C.), and the European Research Council Starting Grant
  850529: E-DIRECT (to C.H.). The funders had no role in study design, data collection
  and analysis, decision to publish, or preparation of the manuscript."
article_number: e1010149
article_processing_charge: No
article_type: original
author:
- first_name: Laura
  full_name: Schmid, Laura
  id: 38B437DE-F248-11E8-B48F-1D18A9856A87
  last_name: Schmid
  orcid: 0000-0002-6978-7329
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Schmid L, Hilbe C, Chatterjee K, Nowak M. Direct reciprocity between individuals
    that use different strategy spaces. <i>PLOS Computational Biology</i>. 2022;18(6).
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1010149">10.1371/journal.pcbi.1010149</a>
  apa: Schmid, L., Hilbe, C., Chatterjee, K., &#38; Nowak, M. (2022). Direct reciprocity
    between individuals that use different strategy spaces. <i>PLOS Computational
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1010149">https://doi.org/10.1371/journal.pcbi.1010149</a>
  chicago: Schmid, Laura, Christian Hilbe, Krishnendu Chatterjee, and Martin Nowak.
    “Direct Reciprocity between Individuals That Use Different Strategy Spaces.” <i>PLOS
    Computational Biology</i>. Public Library of Science, 2022. <a href="https://doi.org/10.1371/journal.pcbi.1010149">https://doi.org/10.1371/journal.pcbi.1010149</a>.
  ieee: L. Schmid, C. Hilbe, K. Chatterjee, and M. Nowak, “Direct reciprocity between
    individuals that use different strategy spaces,” <i>PLOS Computational Biology</i>,
    vol. 18, no. 6. Public Library of Science, 2022.
  ista: Schmid L, Hilbe C, Chatterjee K, Nowak M. 2022. Direct reciprocity between
    individuals that use different strategy spaces. PLOS Computational Biology. 18(6),
    e1010149.
  mla: Schmid, Laura, et al. “Direct Reciprocity between Individuals That Use Different
    Strategy Spaces.” <i>PLOS Computational Biology</i>, vol. 18, no. 6, e1010149,
    Public Library of Science, 2022, doi:<a href="https://doi.org/10.1371/journal.pcbi.1010149">10.1371/journal.pcbi.1010149</a>.
  short: L. Schmid, C. Hilbe, K. Chatterjee, M. Nowak, PLOS Computational Biology
    18 (2022).
corr_author: '1'
date_created: 2023-01-16T10:02:51Z
date_published: 2022-06-14T00:00:00Z
date_updated: 2025-04-14T07:52:47Z
day: '14'
ddc:
- '000'
- '570'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1010149
ec_funded: 1
external_id:
  isi:
  - '000843626800031'
  pmid:
  - '35700167'
file:
- access_level: open_access
  checksum: 31b6b311b6731f1658277a9dfff6632c
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-30T11:28:13Z
  date_updated: 2023-01-30T11:28:13Z
  file_id: '12460'
  file_name: 2022_PlosCompBio_Schmid.pdf
  file_size: 3143222
  relation: main_file
  success: 1
file_date_updated: 2023-01-30T11:28:13Z
has_accepted_license: '1'
intvolume: '        18'
isi: 1
issue: '6'
keyword:
- Computational Theory and Mathematics
- Cellular and Molecular Neuroscience
- Genetics
- Molecular Biology
- Ecology
- Modeling and Simulation
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: PLOS Computational Biology
publication_identifier:
  eissn:
  - 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Direct reciprocity between individuals that use different strategy spaces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 18
year: '2022'
...
---
_id: '12281'
abstract:
- lang: eng
  text: We study the hydrodynamic and hydrostatic limits of the one-dimensional open
    symmetric inclusion process with slow boundary. Depending on the value of the
    parameter tuning the interaction rate of the bulk of the system with the boundary,
    we obtain a linear heat equation with either Dirichlet, Robin or Neumann boundary
    conditions as hydrodynamic equation. In our approach, we combine duality and first-second
    class particle techniques to reduce the scaling limit of the inclusion process
    to the limiting behavior of a single, non-interacting, particle.
acknowledgement: "C.F. and P.G. thank FCT/Portugal for support through the project
  UID/MAT/04459/2013.\r\nThis project has received funding from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovative programme
  (grant agreement No. 715734). F.S. was founded by the European Union’s Horizon 2020
  research and innovation programme under the Marie-Skłodowska-Curie grant agreement
  No. 754411.\r\nF.S. wishes to thank Joe P. Chen for some fruitful discussions at
  an early stage of this work. F.S. thanks CAMGSD, IST, Lisbon, where part of this
  work has been done, and the European research and innovative programme No. 715734
  for the kind hospitality."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Chiara
  full_name: Franceschini, Chiara
  last_name: Franceschini
- first_name: Patrícia
  full_name: Gonçalves, Patrícia
  last_name: Gonçalves
- first_name: Federico
  full_name: Sau, Federico
  id: E1836206-9F16-11E9-8814-AEFDE5697425
  last_name: Sau
citation:
  ama: 'Franceschini C, Gonçalves P, Sau F. Symmetric inclusion process with slow
    boundary: Hydrodynamics and hydrostatics. <i>Bernoulli</i>. 2022;28(2):1340-1381.
    doi:<a href="https://doi.org/10.3150/21-bej1390">10.3150/21-bej1390</a>'
  apa: 'Franceschini, C., Gonçalves, P., &#38; Sau, F. (2022). Symmetric inclusion
    process with slow boundary: Hydrodynamics and hydrostatics. <i>Bernoulli</i>.
    Bernoulli Society for Mathematical Statistics and Probability. <a href="https://doi.org/10.3150/21-bej1390">https://doi.org/10.3150/21-bej1390</a>'
  chicago: 'Franceschini, Chiara, Patrícia Gonçalves, and Federico Sau. “Symmetric
    Inclusion Process with Slow Boundary: Hydrodynamics and Hydrostatics.” <i>Bernoulli</i>.
    Bernoulli Society for Mathematical Statistics and Probability, 2022. <a href="https://doi.org/10.3150/21-bej1390">https://doi.org/10.3150/21-bej1390</a>.'
  ieee: 'C. Franceschini, P. Gonçalves, and F. Sau, “Symmetric inclusion process with
    slow boundary: Hydrodynamics and hydrostatics,” <i>Bernoulli</i>, vol. 28, no.
    2. Bernoulli Society for Mathematical Statistics and Probability, pp. 1340–1381,
    2022.'
  ista: 'Franceschini C, Gonçalves P, Sau F. 2022. Symmetric inclusion process with
    slow boundary: Hydrodynamics and hydrostatics. Bernoulli. 28(2), 1340–1381.'
  mla: 'Franceschini, Chiara, et al. “Symmetric Inclusion Process with Slow Boundary:
    Hydrodynamics and Hydrostatics.” <i>Bernoulli</i>, vol. 28, no. 2, Bernoulli Society
    for Mathematical Statistics and Probability, 2022, pp. 1340–81, doi:<a href="https://doi.org/10.3150/21-bej1390">10.3150/21-bej1390</a>.'
  short: C. Franceschini, P. Gonçalves, F. Sau, Bernoulli 28 (2022) 1340–1381.
date_created: 2023-01-16T10:03:04Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2025-04-14T07:44:00Z
day: '01'
department:
- _id: JaMa
doi: 10.3150/21-bej1390
ec_funded: 1
external_id:
  arxiv:
  - '2007.11998'
  isi:
  - '000766619100025'
intvolume: '        28'
isi: 1
issue: '2'
keyword:
- Statistics and Probability
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2007.11998
month: '05'
oa: 1
oa_version: Preprint
page: 1340-1381
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Bernoulli
publication_identifier:
  issn:
  - 1350-7265
publication_status: published
publisher: Bernoulli Society for Mathematical Statistics and Probability
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Symmetric inclusion process with slow boundary: Hydrodynamics and hydrostatics'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 28
year: '2022'
...
