---
_id: '8167'
abstract:
- lang: eng
text: The evolution of strong reproductive isolation (RI) is fundamental to the
origins and maintenance of biological diversity, especially in situations where
geographical distributions of taxa broadly overlap. But what is the history behind
strong barriers currently acting in sympatry? Using whole-genome sequencing and
single nucleotide polymorphism genotyping, we inferred (i) the evolutionary relationships,
(ii) the strength of RI, and (iii) the demographic history of divergence between
two broadly sympatric taxa of intertidal snail. Despite being cryptic, based on
external morphology, Littorina arcana and Littorina saxatilis differ in their
mode of female reproduction (egg-laying versus brooding), which may generate a
strong post-zygotic barrier. We show that egg-laying and brooding snails are closely
related, but genetically distinct. Genotyping of 3092 snails from three locations
failed to recover any recent hybrid or backcrossed individuals, confirming that
RI is strong. There was, however, evidence for a very low level of asymmetrical
introgression, suggesting that isolation remains incomplete. The presence of strong,
asymmetrical RI was further supported by demographic analysis of these populations.
Although the taxa are currently broadly sympatric, demographic modelling suggests
that they initially diverged during a short period of geographical separation
involving very low gene flow. Our study suggests that some geographical separation
may kick-start the evolution of strong RI, facilitating subsequent coexistence
of taxa in sympatry. The strength of RI needed to achieve sympatry and the subsequent
effect of sympatry on RI remain open questions.
acknowledgement: Funding was provided by the Natural Environment Research Council
(NERC) and the European Research Council. We thank Rui Faria, Nicola Nadeau, Martin
Garlovsky and Hernan Morales for advice and/or useful discussion during the project.
Richard Turney, Graciela Sotelo, Jenny Larson, Stéphane Loisel and Meghan Wharton
participated in the collection and processing of samples. Mark Dunning helped with
the development of bioinformatic pipelines. The analysis of genomic data was conducted
on the University of Sheffield High-performance computer, ShARC. Jeffrey Feder and
an anonymous reviewer provided comments that improved the manuscript.
article_number: '20190545'
article_processing_charge: No
article_type: original
author:
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Zuzanna B.
full_name: Zagrodzka, Zuzanna B.
last_name: Zagrodzka
- first_name: Isobel
full_name: Eyres, Isobel
last_name: Eyres
- first_name: Thomas
full_name: Broquet, Thomas
last_name: Broquet
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: 'Stankowski S, Westram AM, Zagrodzka ZB, et al. The evolution of strong reproductive
isolation between sympatric intertidal snails. Philosophical Transactions of
the Royal Society Series B: Biological Sciences. 2020;375(1806). doi:10.1098/rstb.2019.0545'
apa: 'Stankowski, S., Westram, A. M., Zagrodzka, Z. B., Eyres, I., Broquet, T.,
Johannesson, K., & Butlin, R. K. (2020). The evolution of strong reproductive
isolation between sympatric intertidal snails. Philosophical Transactions of
the Royal Society. Series B: Biological Sciences. The Royal Society. https://doi.org/10.1098/rstb.2019.0545'
chicago: 'Stankowski, Sean, Anja M Westram, Zuzanna B. Zagrodzka, Isobel Eyres,
Thomas Broquet, Kerstin Johannesson, and Roger K. Butlin. “The Evolution of Strong
Reproductive Isolation between Sympatric Intertidal Snails.” Philosophical
Transactions of the Royal Society. Series B: Biological Sciences. The Royal
Society, 2020. https://doi.org/10.1098/rstb.2019.0545.'
ieee: 'S. Stankowski et al., “The evolution of strong reproductive isolation
between sympatric intertidal snails,” Philosophical Transactions of the Royal
Society. Series B: Biological Sciences, vol. 375, no. 1806. The Royal Society,
2020.'
ista: 'Stankowski S, Westram AM, Zagrodzka ZB, Eyres I, Broquet T, Johannesson K,
Butlin RK. 2020. The evolution of strong reproductive isolation between sympatric
intertidal snails. Philosophical Transactions of the Royal Society. Series B:
Biological Sciences. 375(1806), 20190545.'
mla: 'Stankowski, Sean, et al. “The Evolution of Strong Reproductive Isolation between
Sympatric Intertidal Snails.” Philosophical Transactions of the Royal Society.
Series B: Biological Sciences, vol. 375, no. 1806, 20190545, The Royal Society,
2020, doi:10.1098/rstb.2019.0545.'
short: 'S. Stankowski, A.M. Westram, Z.B. Zagrodzka, I. Eyres, T. Broquet, K. Johannesson,
R.K. Butlin, Philosophical Transactions of the Royal Society. Series B: Biological
Sciences 375 (2020).'
date_created: 2020-07-26T22:01:01Z
date_published: 2020-07-12T00:00:00Z
date_updated: 2026-06-18T19:30:29Z
day: '12'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1098/rstb.2019.0545
external_id:
isi:
- '000552662100014'
pmid:
- '32654639'
intvolume: ' 375'
isi: 1
issue: '1806'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1098/rstb.2019.0545
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: 'Philosophical Transactions of the Royal Society. Series B: Biological
Sciences'
publication_identifier:
eissn:
- 1471-2970
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: The evolution of strong reproductive isolation between sympatric intertidal
snails
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 375
year: '2020'
...
---
_id: '8168'
abstract:
- lang: eng
text: Speciation, that is, the evolution of reproductive barriers eventually leading
to complete isolation, is a crucial process generating biodiversity. Recent work
has contributed much to our understanding of how reproductive barriers begin to
evolve, and how they are maintained in the face of gene flow. However, little
is known about the transition from partial to strong reproductive isolation (RI)
and the completion of speciation. We argue that the evolution of strong RI is
likely to involve different processes, or new interactions among processes, compared
with the evolution of the first reproductive barriers. Transition to strong RI
may be brought about by changing external conditions, for example, following secondary
contact. However, the increasing levels of RI themselves create opportunities
for new barriers to evolve and, and interaction or coupling among barriers. These
changing processes may depend on genomic architecture and leave detectable signals
in the genome. We outline outstanding questions and suggest more theoretical and
empirical work, considering both patterns and processes associated with strong
RI, is needed to understand how speciation is completed.
article_number: '20190528'
article_processing_charge: No
article_type: original
author:
- first_name: Jonna
full_name: Kulmuni, Jonna
last_name: Kulmuni
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Kay
full_name: Lucek, Kay
last_name: Lucek
- first_name: Vincent
full_name: Savolainen, Vincent
last_name: Savolainen
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Kulmuni J, Butlin RK, Lucek K, Savolainen V, Westram AM. Towards the completion
of speciation: The evolution of reproductive isolation beyond the first barriers.
Philosophical Transactions of the Royal Society Series B: Biological sciences.
2020;375(1806). doi:10.1098/rstb.2019.0528'
apa: 'Kulmuni, J., Butlin, R. K., Lucek, K., Savolainen, V., & Westram, A. M.
(2020). Towards the completion of speciation: The evolution of reproductive isolation
beyond the first barriers. Philosophical Transactions of the Royal Society.
Series B: Biological Sciences. The Royal Society. https://doi.org/10.1098/rstb.2019.0528'
chicago: 'Kulmuni, Jonna, Roger K. Butlin, Kay Lucek, Vincent Savolainen, and Anja
M Westram. “Towards the Completion of Speciation: The Evolution of Reproductive
Isolation beyond the First Barriers.” Philosophical Transactions of the Royal
Society. Series B: Biological Sciences. The Royal Society, 2020. https://doi.org/10.1098/rstb.2019.0528.'
ieee: 'J. Kulmuni, R. K. Butlin, K. Lucek, V. Savolainen, and A. M. Westram, “Towards
the completion of speciation: The evolution of reproductive isolation beyond the
first barriers,” Philosophical Transactions of the Royal Society. Series B:
Biological sciences, vol. 375, no. 1806. The Royal Society, 2020.'
ista: 'Kulmuni J, Butlin RK, Lucek K, Savolainen V, Westram AM. 2020. Towards the
completion of speciation: The evolution of reproductive isolation beyond the first
barriers. Philosophical Transactions of the Royal Society. Series B: Biological
sciences. 375(1806), 20190528.'
mla: 'Kulmuni, Jonna, et al. “Towards the Completion of Speciation: The Evolution
of Reproductive Isolation beyond the First Barriers.” Philosophical Transactions
of the Royal Society. Series B: Biological Sciences, vol. 375, no. 1806, 20190528,
The Royal Society, 2020, doi:10.1098/rstb.2019.0528.'
short: 'J. Kulmuni, R.K. Butlin, K. Lucek, V. Savolainen, A.M. Westram, Philosophical
Transactions of the Royal Society. Series B: Biological Sciences 375 (2020).'
date_created: 2020-07-26T22:01:01Z
date_published: 2020-07-12T00:00:00Z
date_updated: 2026-06-18T19:30:51Z
day: '12'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1098/rstb.2019.0528
ec_funded: 1
external_id:
isi:
- '000552662100001'
pmid:
- '32654637'
intvolume: ' 375'
isi: 1
issue: '1806'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1098/rstb.2019.0528
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 265B41B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '797747'
name: Theoretical and empirical approaches to understanding Parallel Adaptation
publication: 'Philosophical Transactions of the Royal Society. Series B: Biological
sciences'
publication_identifier:
eissn:
- 1471-2970
issn:
- 0962-8436
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Towards the completion of speciation: The evolution of reproductive isolation
beyond the first barriers'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 375
year: '2020'
...
---
_id: '8170'
abstract:
- lang: eng
text: "Alignment of OCS, CS2, and I2 molecules embedded in helium nanodroplets is
measured as a function\r\nof time following rotational excitation by a nonresonant,
comparatively weak ps laser pulse. The distinct\r\npeaks in the power spectra,
obtained by Fourier analysis, are used to determine the rotational, B, and\r\ncentrifugal
distortion, D, constants. For OCS, B and D match the values known from IR spectroscopy.
For\r\nCS2 and I2, they are the first experimental results reported. The alignment
dynamics calculated from the\r\ngas-phase rotational Schrödinger equation, using
the experimental in-droplet B and D values, agree in\r\ndetail with the measurement
for all three molecules. The rotational spectroscopy technique for molecules in\r\nhelium
droplets introduced here should apply to a range of molecules and complexes."
acknowledgement: "H. S. acknowledges support from the European Research Council-AdG
(Project No. 320459, DropletControl)\r\nand from The Villum Foundation through a
Villum Investigator Grant No. 25886. M. L. acknowledges support\r\nby the Austrian
Science Fund (FWF), under Project No. P29902-N27, and by the European Research Council\r\n(ERC)
Starting Grant No. 801770 (ANGULON). G. B. acknowledges support from the Austrian
Science Fund\r\n(FWF), under Project No. M2641-N27. I. C. acknowledges support by
the European Union’s Horizon 2020 research and\r\ninnovation programme under the
Marie Skłodowska-Curie Grant Agreement No. 665385. Computational resources for\r\nthe
PIMC simulations were provided by the division for scientific computing at the Johannes
Kepler University."
article_number: '013001'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Adam S.
full_name: Chatterley, Adam S.
last_name: Chatterley
- first_name: Lars
full_name: Christiansen, Lars
last_name: Christiansen
- first_name: Constant A.
full_name: Schouder, Constant A.
last_name: Schouder
- first_name: Anders V.
full_name: Jørgensen, Anders V.
last_name: Jørgensen
- first_name: Benjamin
full_name: Shepperson, Benjamin
last_name: Shepperson
- first_name: Igor
full_name: Cherepanov, Igor
id: 339C7E5A-F248-11E8-B48F-1D18A9856A87
last_name: Cherepanov
- first_name: Giacomo
full_name: Bighin, Giacomo
id: 4CA96FD4-F248-11E8-B48F-1D18A9856A87
last_name: Bighin
orcid: 0000-0001-8823-9777
- first_name: Robert E.
full_name: Zillich, Robert E.
last_name: Zillich
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
- first_name: Henrik
full_name: Stapelfeldt, Henrik
last_name: Stapelfeldt
citation:
ama: 'Chatterley AS, Christiansen L, Schouder CA, et al. Rotational coherence spectroscopy
of molecules in Helium nanodroplets: Reconciling the time and the frequency domains.
Physical Review Letters. 2020;125(1). doi:10.1103/PhysRevLett.125.013001'
apa: 'Chatterley, A. S., Christiansen, L., Schouder, C. A., Jørgensen, A. V., Shepperson,
B., Cherepanov, I., … Stapelfeldt, H. (2020). Rotational coherence spectroscopy
of molecules in Helium nanodroplets: Reconciling the time and the frequency domains.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.125.013001'
chicago: 'Chatterley, Adam S., Lars Christiansen, Constant A. Schouder, Anders V.
Jørgensen, Benjamin Shepperson, Igor Cherepanov, Giacomo Bighin, Robert E. Zillich,
Mikhail Lemeshko, and Henrik Stapelfeldt. “Rotational Coherence Spectroscopy of
Molecules in Helium Nanodroplets: Reconciling the Time and the Frequency Domains.”
Physical Review Letters. American Physical Society, 2020. https://doi.org/10.1103/PhysRevLett.125.013001.'
ieee: 'A. S. Chatterley et al., “Rotational coherence spectroscopy of molecules
in Helium nanodroplets: Reconciling the time and the frequency domains,” Physical
Review Letters, vol. 125, no. 1. American Physical Society, 2020.'
ista: 'Chatterley AS, Christiansen L, Schouder CA, Jørgensen AV, Shepperson B, Cherepanov
I, Bighin G, Zillich RE, Lemeshko M, Stapelfeldt H. 2020. Rotational coherence
spectroscopy of molecules in Helium nanodroplets: Reconciling the time and the
frequency domains. Physical Review Letters. 125(1), 013001.'
mla: 'Chatterley, Adam S., et al. “Rotational Coherence Spectroscopy of Molecules
in Helium Nanodroplets: Reconciling the Time and the Frequency Domains.” Physical
Review Letters, vol. 125, no. 1, 013001, American Physical Society, 2020,
doi:10.1103/PhysRevLett.125.013001.'
short: A.S. Chatterley, L. Christiansen, C.A. Schouder, A.V. Jørgensen, B. Shepperson,
I. Cherepanov, G. Bighin, R.E. Zillich, M. Lemeshko, H. Stapelfeldt, Physical
Review Letters 125 (2020).
date_created: 2020-07-26T22:01:02Z
date_published: 2020-07-03T00:00:00Z
date_updated: 2026-04-16T08:21:58Z
day: '03'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.125.013001
ec_funded: 1
external_id:
arxiv:
- '2006.02694'
isi:
- '000544526900006'
pmid:
- '32678640'
intvolume: ' 125'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2006.02694
month: '07'
oa: 1
oa_version: Preprint
pmid: 1
project:
- _id: 26031614-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P29902
name: Quantum rotations in the presence of a many-body environment
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '801770'
name: 'Angulon: physics and applications of a new quasiparticle'
- _id: 26986C82-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02641
name: A path-integral approach to composite impurities
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Rotational coherence spectroscopy of molecules in Helium nanodroplets: Reconciling
the time and the frequency domains'
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 125
year: '2020'
...
---
_id: '8181'
author:
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
citation:
ama: Hauschild R. Amplified centrosomes in dendritic cells promote immune cell effector
functions. 2020. doi:10.15479/AT:ISTA:8181
apa: Hauschild, R. (2020). Amplified centrosomes in dendritic cells promote immune
cell effector functions. IST Austria. https://doi.org/10.15479/AT:ISTA:8181
chicago: Hauschild, Robert. “Amplified Centrosomes in Dendritic Cells Promote Immune
Cell Effector Functions.” IST Austria, 2020. https://doi.org/10.15479/AT:ISTA:8181.
ieee: R. Hauschild, “Amplified centrosomes in dendritic cells promote immune cell
effector functions.” IST Austria, 2020.
ista: Hauschild R. 2020. Amplified centrosomes in dendritic cells promote immune
cell effector functions, IST Austria, 10.15479/AT:ISTA:8181.
mla: Hauschild, Robert. Amplified Centrosomes in Dendritic Cells Promote Immune
Cell Effector Functions. IST Austria, 2020, doi:10.15479/AT:ISTA:8181.
short: R. Hauschild, (2020).
corr_author: '1'
date_created: 2020-07-28T16:24:37Z
date_published: 2020-08-24T00:00:00Z
date_updated: 2024-10-09T21:05:14Z
day: '24'
department:
- _id: Bio
doi: 10.15479/AT:ISTA:8181
file:
- access_level: open_access
checksum: 878c60885ce30afb59a884dd5eef451c
content_type: text/plain
creator: rhauschild
date_created: 2020-08-24T15:43:49Z
date_updated: 2020-08-24T15:43:49Z
file_id: '8290'
file_name: centriolesDistance.m
file_size: 6577
relation: main_file
success: 1
- access_level: open_access
checksum: 5a93ac7be2b66b28e4bd8b113ee6aade
content_type: text/plain
creator: rhauschild
date_created: 2020-08-24T15:43:52Z
date_updated: 2020-08-24T15:43:52Z
file_id: '8291'
file_name: goTracking.m
file_size: 2680
relation: main_file
success: 1
file_date_updated: 2020-08-24T15:43:52Z
has_accepted_license: '1'
license: https://opensource.org/licenses/BSD-3-Clause
month: '08'
oa: 1
publisher: IST Austria
status: public
title: Amplified centrosomes in dendritic cells promote immune cell effector functions
tmp:
legal_code_url: https://opensource.org/licenses/BSD-3-Clause
name: The 3-Clause BSD License
short: 3-Clause BSD
type: software
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8186'
abstract:
- lang: eng
text: "Numerous methods have been proposed for probabilistic generative modelling
of\r\n3D objects. However, none of these is able to produce textured objects,
which\r\nrenders them of limited use for practical tasks. In this work, we present
the\r\nfirst generative model of textured 3D meshes. Training such a model would\r\ntraditionally
require a large dataset of textured meshes, but unfortunately,\r\nexisting datasets
of meshes lack detailed textures. We instead propose a new\r\ntraining methodology
that allows learning from collections of 2D images without\r\nany 3D information.
To do so, we train our model to explain a distribution of\r\nimages by modelling
each image as a 3D foreground object placed in front of a\r\n2D background. Thus,
it learns to generate meshes that when rendered, produce\r\nimages similar to
those in its training set.\r\n A well-known problem when generating meshes with
deep networks is the\r\nemergence of self-intersections, which are problematic
for many use-cases. As a\r\nsecond contribution we therefore introduce a new generation
process for 3D\r\nmeshes that guarantees no self-intersections arise, based on
the physical\r\nintuition that faces should push one another out of the way as
they move.\r\n We conduct extensive experiments on our approach, reporting quantitative
and\r\nqualitative results on both synthetic data and natural images. These show
our\r\nmethod successfully learns to generate plausible and diverse textured 3D\r\nsamples
for five challenging object classes."
article_processing_charge: No
arxiv: 1
author:
- first_name: Paul M
full_name: Henderson, Paul M
id: 13C09E74-18D9-11E9-8878-32CFE5697425
last_name: Henderson
orcid: 0000-0002-5198-7445
- first_name: Vagia
full_name: Tsiminaki, Vagia
last_name: Tsiminaki
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Henderson PM, Tsiminaki V, Lampert C. Leveraging 2D data to learn textured
3D mesh generation. In: Proceedings of the IEEE/CVF Conference on Computer
Vision and Pattern Recognition. IEEE; 2020:7498-7507. doi:10.1109/CVPR42600.2020.00752'
apa: 'Henderson, P. M., Tsiminaki, V., & Lampert, C. (2020). Leveraging 2D data
to learn textured 3D mesh generation. In Proceedings of the IEEE/CVF Conference
on Computer Vision and Pattern Recognition (pp. 7498–7507). Virtual: IEEE.
https://doi.org/10.1109/CVPR42600.2020.00752'
chicago: Henderson, Paul M, Vagia Tsiminaki, and Christoph Lampert. “Leveraging
2D Data to Learn Textured 3D Mesh Generation.” In Proceedings of the IEEE/CVF
Conference on Computer Vision and Pattern Recognition, 7498–7507. IEEE, 2020.
https://doi.org/10.1109/CVPR42600.2020.00752.
ieee: P. M. Henderson, V. Tsiminaki, and C. Lampert, “Leveraging 2D data to learn
textured 3D mesh generation,” in Proceedings of the IEEE/CVF Conference on
Computer Vision and Pattern Recognition, Virtual, 2020, pp. 7498–7507.
ista: 'Henderson PM, Tsiminaki V, Lampert C. 2020. Leveraging 2D data to learn textured
3D mesh generation. Proceedings of the IEEE/CVF Conference on Computer Vision
and Pattern Recognition. CVPR: Conference on Computer Vision and Pattern Recognition,
7498–7507.'
mla: Henderson, Paul M., et al. “Leveraging 2D Data to Learn Textured 3D Mesh Generation.”
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition,
IEEE, 2020, pp. 7498–507, doi:10.1109/CVPR42600.2020.00752.
short: P.M. Henderson, V. Tsiminaki, C. Lampert, in:, Proceedings of the IEEE/CVF
Conference on Computer Vision and Pattern Recognition, IEEE, 2020, pp. 7498–7507.
conference:
end_date: 2020-06-19
location: Virtual
name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
start_date: 2020-06-14
date_created: 2020-07-31T16:53:49Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-10-17T07:37:11Z
day: '01'
ddc:
- '004'
department:
- _id: ChLa
doi: 10.1109/CVPR42600.2020.00752
external_id:
arxiv:
- '2004.04180'
file:
- access_level: open_access
content_type: application/pdf
creator: phenders
date_created: 2020-07-31T16:57:12Z
date_updated: 2020-07-31T16:57:12Z
file_id: '8187'
file_name: paper.pdf
file_size: 10262773
relation: main_file
success: 1
file_date_updated: 2020-07-31T16:57:12Z
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://openaccess.thecvf.com/content_CVPR_2020/papers/Henderson_Leveraging_2D_Data_to_Learn_Textured_3D_Mesh_Generation_CVPR_2020_paper.pdf
month: '07'
oa: 1
oa_version: Submitted Version
page: 7498-7507
publication: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern
Recognition
publication_identifier:
eisbn:
- '9781728171685'
eissn:
- 2575-7075
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Leveraging 2D data to learn textured 3D mesh generation
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8188'
abstract:
- lang: eng
text: "A natural approach to generative modeling of videos is to represent them
as a composition of moving objects. Recent works model a set of 2D sprites over
a slowly-varying background, but without considering the underlying 3D scene that\r\ngives
rise to them. We instead propose to model a video as the view seen while moving
through a scene with multiple 3D objects and a 3D background. Our model is trained
from monocular videos without any supervision, yet learns to\r\ngenerate coherent
3D scenes containing several moving objects. We conduct detailed experiments on
two datasets, going beyond the visual complexity supported by state-of-the-art
generative approaches. We evaluate our method on\r\ndepth-prediction and 3D object
detection---tasks which cannot be addressed by those earlier works---and show
it out-performs them even on 2D instance segmentation and tracking."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "This research was supported by the Scientific Service Units (SSU)
of IST Austria through resources\r\nprovided by Scientific Computing (SciComp).
PH is employed part-time by Blackford Analysis, but\r\nthey did not support this
project in any way."
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Paul M
full_name: Henderson, Paul M
id: 13C09E74-18D9-11E9-8878-32CFE5697425
last_name: Henderson
orcid: 0000-0002-5198-7445
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Henderson PM, Lampert C. Unsupervised object-centric video generation and
decomposition in 3D. In: 34th Conference on Neural Information Processing Systems.
Vol 33. Neural Information Processing Systems Foundation; 2020:3106–3117.'
apa: 'Henderson, P. M., & Lampert, C. (2020). Unsupervised object-centric video
generation and decomposition in 3D. In 34th Conference on Neural Information
Processing Systems (Vol. 33, pp. 3106–3117). Vancouver, Canada: Neural Information
Processing Systems Foundation.'
chicago: Henderson, Paul M, and Christoph Lampert. “Unsupervised Object-Centric
Video Generation and Decomposition in 3D.” In 34th Conference on Neural Information
Processing Systems, 33:3106–3117. Neural Information Processing Systems Foundation,
2020.
ieee: P. M. Henderson and C. Lampert, “Unsupervised object-centric video generation
and decomposition in 3D,” in 34th Conference on Neural Information Processing
Systems, Vancouver, Canada, 2020, vol. 33, pp. 3106–3117.
ista: 'Henderson PM, Lampert C. 2020. Unsupervised object-centric video generation
and decomposition in 3D. 34th Conference on Neural Information Processing Systems.
NeurIPS: Neural Information Processing Systems, Advances in Neural Information
Processing Systems, vol. 33, 3106–3117.'
mla: Henderson, Paul M., and Christoph Lampert. “Unsupervised Object-Centric Video
Generation and Decomposition in 3D.” 34th Conference on Neural Information
Processing Systems, vol. 33, Neural Information Processing Systems Foundation,
2020, pp. 3106–3117.
short: P.M. Henderson, C. Lampert, in:, 34th Conference on Neural Information Processing
Systems, Neural Information Processing Systems Foundation, 2020, pp. 3106–3117.
conference:
end_date: 2020-12-12
location: Vancouver, Canada
name: 'NeurIPS: Neural Information Processing Systems'
start_date: 2020-12-06
corr_author: '1'
date_created: 2020-07-31T16:59:19Z
date_published: 2020-07-07T00:00:00Z
date_updated: 2025-05-14T11:26:57Z
day: '07'
department:
- _id: ChLa
external_id:
arxiv:
- '2007.06705'
intvolume: ' 33'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2007.06705
month: '07'
oa: 1
oa_version: Preprint
page: 3106–3117
publication: 34th Conference on Neural Information Processing Systems
publication_identifier:
isbn:
- '9781713829546'
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
status: public
title: Unsupervised object-centric video generation and decomposition in 3D
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2020'
...
---
OA_place: repository
OA_type: green
_id: '8189'
abstract:
- lang: eng
text: Direct ethanol fuel cells (DEFCs) show a huge potential to power future electric
vehicles and portable electronics, but their deployment is currently limited by
the unavailability of proper electrocatalysis for the ethanol oxidation reaction
(EOR). In this work, we engineer a new electrocatalyst by incorporating phosphorous
into a palladium-tin alloy and demonstrate a significant performance improvement
toward EOR. We first detail a synthetic method to produce Pd2Sn:P nanocrystals
that incorporate 35% of phosphorus. These nanoparticles are supported on carbon
black and tested for EOR. Pd2Sn:P/C catalysts exhibit mass current densities up
to 5.03 A mgPd−1, well above those of Pd2Sn/C, PdP2/C and Pd/C reference catalysts.
Furthermore, a twofold lower Tafel slope and a much longer durability are revealed
for the Pd2Sn:P/C catalyst compared with Pd/C. The performance improvement is
rationalized with the aid of density functional theory (DFT) calculations considering
different phosphorous chemical environments. Depending on its oxidation state,
surface phosphorus introduces sites with low energy OH− adsorption and/or strongly
influences the electronic structure of palladium and tin to facilitate the oxidation
of the acetyl to acetic acid, which is considered the EOR rate limiting step.
DFT calculations also points out that the durability improvement of Pd2Sn:P/C
catalyst is associated to the promotion of OH adsorption that accelerates the
oxidation of intermediate poisoning COads, reactivating the catalyst surface.
acknowledgement: This work was supported by the European Regional Development Funds
and by the Spanish Ministerio de Economía y Competitividad through the project SEHTOP,
ENE2016- 77798-C4-3-R, and ENE2017-85087-C3. X. Y. thanks the China Scholarship
Council for the scholarship support. J. Liu acknowledges support from the Jiangsu
University Foundation (4111510011). J. Li obtained International Postdoctoral Exchange
Fellowship Program (Talent-Introduction program) in 2019 and is grateful for the
project (2019M663468) funded by the China Postdoctoral Science Foundation. Authors
acknowledge funding from Generalitat de Catalunya 2017 SGR 327 and 2017 SGR 1246,
and from IST Austria. ICN2 acknowledges the support from the Severo Ochoa Programme
(MINECO, grant no. SEV-2017-0706) and is funded by the CERCA Programme/Generalitat
de Catalunya. J. Llorca is a Serra Húnter Fellow and is grateful to MICINN/FEDER
RTI2018-093996-B-C31, GC 2017 SGR 128 and to ICREA Academia program.
article_number: '105116'
article_processing_charge: No
article_type: original
author:
- first_name: Xiaoting
full_name: Yu, Xiaoting
last_name: Yu
- first_name: Junfeng
full_name: Liu, Junfeng
last_name: Liu
- first_name: Junshan
full_name: Li, Junshan
last_name: Li
- first_name: Zhishan
full_name: Luo, Zhishan
last_name: Luo
- first_name: Yong
full_name: Zuo, Yong
last_name: Zuo
- first_name: Congcong
full_name: Xing, Congcong
last_name: Xing
- first_name: Jordi
full_name: Llorca, Jordi
last_name: Llorca
- first_name: Déspina
full_name: Nasiou, Déspina
last_name: Nasiou
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Kai
full_name: Pan, Kai
last_name: Pan
- first_name: Tobias
full_name: Kleinhanns, Tobias
id: 8BD9DE16-AB3C-11E9-9C8C-2A03E6697425
last_name: Kleinhanns
- first_name: Ying
full_name: Xie, Ying
last_name: Xie
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: Yu X, Liu J, Li J, et al. Phosphorous incorporation in Pd2Sn alloys for electrocatalytic
ethanol oxidation. Nano Energy. 2020;77(11). doi:10.1016/j.nanoen.2020.105116
apa: Yu, X., Liu, J., Li, J., Luo, Z., Zuo, Y., Xing, C., … Cabot, A. (2020). Phosphorous
incorporation in Pd2Sn alloys for electrocatalytic ethanol oxidation. Nano
Energy. Elsevier. https://doi.org/10.1016/j.nanoen.2020.105116
chicago: Yu, Xiaoting, Junfeng Liu, Junshan Li, Zhishan Luo, Yong Zuo, Congcong
Xing, Jordi Llorca, et al. “Phosphorous Incorporation in Pd2Sn Alloys for Electrocatalytic
Ethanol Oxidation.” Nano Energy. Elsevier, 2020. https://doi.org/10.1016/j.nanoen.2020.105116.
ieee: X. Yu et al., “Phosphorous incorporation in Pd2Sn alloys for electrocatalytic
ethanol oxidation,” Nano Energy, vol. 77, no. 11. Elsevier, 2020.
ista: Yu X, Liu J, Li J, Luo Z, Zuo Y, Xing C, Llorca J, Nasiou D, Arbiol J, Pan
K, Kleinhanns T, Xie Y, Cabot A. 2020. Phosphorous incorporation in Pd2Sn alloys
for electrocatalytic ethanol oxidation. Nano Energy. 77(11), 105116.
mla: Yu, Xiaoting, et al. “Phosphorous Incorporation in Pd2Sn Alloys for Electrocatalytic
Ethanol Oxidation.” Nano Energy, vol. 77, no. 11, 105116, Elsevier, 2020,
doi:10.1016/j.nanoen.2020.105116.
short: X. Yu, J. Liu, J. Li, Z. Luo, Y. Zuo, C. Xing, J. Llorca, D. Nasiou, J. Arbiol,
K. Pan, T. Kleinhanns, Y. Xie, A. Cabot, Nano Energy 77 (2020).
date_created: 2020-08-02T22:00:57Z
date_published: 2020-11-01T00:00:00Z
date_updated: 2025-04-24T11:53:45Z
day: '01'
department:
- _id: MaIb
doi: 10.1016/j.nanoen.2020.105116
external_id:
isi:
- '000581738300030'
intvolume: ' 77'
isi: 1
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://hdl.handle.net/2117/335346
month: '11'
oa: 1
oa_version: Submitted Version
publication: Nano Energy
publication_identifier:
issn:
- 2211-2855
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phosphorous incorporation in Pd2Sn alloys for electrocatalytic ethanol oxidation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 77
year: '2020'
...
---
_id: '8194'
abstract:
- lang: eng
text: 'Fixed-point arithmetic is a popular alternative to floating-point arithmetic
on embedded systems. Existing work on the verification of fixed-point programs
relies on custom formalizations of fixed-point arithmetic, which makes it hard
to compare the described techniques or reuse the implementations. In this paper,
we address this issue by proposing and formalizing an SMT theory of fixed-point
arithmetic. We present an intuitive yet comprehensive syntax of the fixed-point
theory, and provide formal semantics for it based on rational arithmetic. We also
describe two decision procedures for this theory: one based on the theory of bit-vectors
and the other on the theory of reals. We implement the two decision procedures,
and evaluate our implementations using existing mature SMT solvers on a benchmark
suite we created. Finally, we perform a case study of using the theory we propose
to verify properties of quantized neural networks.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Marek
full_name: Baranowski, Marek
last_name: Baranowski
- first_name: Shaobo
full_name: He, Shaobo
last_name: He
- first_name: Mathias
full_name: Lechner, Mathias
id: 3DC22916-F248-11E8-B48F-1D18A9856A87
last_name: Lechner
- first_name: Thanh Son
full_name: Nguyen, Thanh Son
last_name: Nguyen
- first_name: Zvonimir
full_name: Rakamarić, Zvonimir
last_name: Rakamarić
citation:
ama: 'Baranowski M, He S, Lechner M, Nguyen TS, Rakamarić Z. An SMT theory of fixed-point
arithmetic. In: Automated Reasoning. Vol 12166. Springer Nature; 2020:13-31.
doi:10.1007/978-3-030-51074-9_2'
apa: 'Baranowski, M., He, S., Lechner, M., Nguyen, T. S., & Rakamarić, Z. (2020).
An SMT theory of fixed-point arithmetic. In Automated Reasoning (Vol. 12166,
pp. 13–31). Paris, France: Springer Nature. https://doi.org/10.1007/978-3-030-51074-9_2'
chicago: Baranowski, Marek, Shaobo He, Mathias Lechner, Thanh Son Nguyen, and Zvonimir
Rakamarić. “An SMT Theory of Fixed-Point Arithmetic.” In Automated Reasoning,
12166:13–31. Springer Nature, 2020. https://doi.org/10.1007/978-3-030-51074-9_2.
ieee: M. Baranowski, S. He, M. Lechner, T. S. Nguyen, and Z. Rakamarić, “An SMT
theory of fixed-point arithmetic,” in Automated Reasoning, Paris, France,
2020, vol. 12166, pp. 13–31.
ista: 'Baranowski M, He S, Lechner M, Nguyen TS, Rakamarić Z. 2020. An SMT theory
of fixed-point arithmetic. Automated Reasoning. IJCAR: International Joint Conference
on Automated Reasoning, LNCS, vol. 12166, 13–31.'
mla: Baranowski, Marek, et al. “An SMT Theory of Fixed-Point Arithmetic.” Automated
Reasoning, vol. 12166, Springer Nature, 2020, pp. 13–31, doi:10.1007/978-3-030-51074-9_2.
short: M. Baranowski, S. He, M. Lechner, T.S. Nguyen, Z. Rakamarić, in:, Automated
Reasoning, Springer Nature, 2020, pp. 13–31.
conference:
end_date: 2020-07-04
location: Paris, France
name: 'IJCAR: International Joint Conference on Automated Reasoning'
start_date: 2020-07-01
date_created: 2020-08-02T22:00:59Z
date_published: 2020-06-24T00:00:00Z
date_updated: 2026-06-18T19:31:14Z
day: '24'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-030-51074-9_2
external_id:
isi:
- '000884318000002'
intvolume: ' 12166'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/978-3-030-51074-9_2
month: '06'
oa: 1
oa_version: Published Version
page: 13-31
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: Formal methods for the design and analysis of complex systems
publication: Automated Reasoning
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783030510732'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: An SMT theory of fixed-point arithmetic
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12166
year: '2020'
...
---
_id: '8195'
abstract:
- lang: eng
text: This paper presents a foundation for refining concurrent programs with structured
control flow. The verification problem is decomposed into subproblems that aid
interactive program development, proof reuse, and automation. The formalization
in this paper is the basis of a new design and implementation of the Civl verifier.
acknowledgement: "Bernhard Kragl and Thomas A. Henzinger were supported by\r\nthe
Austrian Science Fund (FWF) under grant Z211-N23 (Wittgenstein Award)."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Bernhard
full_name: Kragl, Bernhard
id: 320FC952-F248-11E8-B48F-1D18A9856A87
last_name: Kragl
orcid: 0000-0001-7745-9117
- first_name: Shaz
full_name: Qadeer, Shaz
last_name: Qadeer
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000-0002-2985-7724
citation:
ama: 'Kragl B, Qadeer S, Henzinger TA. Refinement for structured concurrent programs.
In: Computer Aided Verification. Vol 12224. Springer Nature; 2020:275-298.
doi:10.1007/978-3-030-53288-8_14'
apa: Kragl, B., Qadeer, S., & Henzinger, T. A. (2020). Refinement for structured
concurrent programs. In Computer Aided Verification (Vol. 12224, pp. 275–298).
Springer Nature. https://doi.org/10.1007/978-3-030-53288-8_14
chicago: Kragl, Bernhard, Shaz Qadeer, and Thomas A Henzinger. “Refinement for Structured
Concurrent Programs.” In Computer Aided Verification, 12224:275–98. Springer
Nature, 2020. https://doi.org/10.1007/978-3-030-53288-8_14.
ieee: B. Kragl, S. Qadeer, and T. A. Henzinger, “Refinement for structured concurrent
programs,” in Computer Aided Verification, 2020, vol. 12224, pp. 275–298.
ista: Kragl B, Qadeer S, Henzinger TA. 2020. Refinement for structured concurrent
programs. Computer Aided Verification. , LNCS, vol. 12224, 275–298.
mla: Kragl, Bernhard, et al. “Refinement for Structured Concurrent Programs.” Computer
Aided Verification, vol. 12224, Springer Nature, 2020, pp. 275–98, doi:10.1007/978-3-030-53288-8_14.
short: B. Kragl, S. Qadeer, T.A. Henzinger, in:, Computer Aided Verification, Springer
Nature, 2020, pp. 275–298.
corr_author: '1'
date_created: 2020-08-03T11:45:35Z
date_published: 2020-07-14T00:00:00Z
date_updated: 2026-04-08T07:23:52Z
day: '14'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-030-53288-8_14
external_id:
isi:
- '000695276000014'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2020-08-06T08:14:54Z
date_updated: 2020-08-06T08:14:54Z
file_id: '8201'
file_name: 2020_LNCS_Kragl.pdf
file_size: 804237
relation: main_file
success: 1
file_date_updated: 2020-08-06T08:14:54Z
has_accepted_license: '1'
intvolume: ' 12224'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 275-298
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: Formal methods for the design and analysis of complex systems
publication: Computer Aided Verification
publication_identifier:
eisbn:
- '9783030532888'
eissn:
- 1611-3349
isbn:
- '9783030532871'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '8332'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Refinement for structured concurrent programs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 12224
year: '2020'
...
---
_id: '8199'
abstract:
- lang: eng
text: We investigate a mechanism to transiently stabilize topological phenomena
in long-lived quasi-steady states of isolated quantum many-body systems driven
at low frequencies. We obtain an analytical bound for the lifetime of the quasi-steady
states which is exponentially large in the inverse driving frequency. Within this
lifetime, the quasi-steady state is characterized by maximum entropy subject to
the constraint of fixed number of particles in the system's Floquet-Bloch bands.
In such a state, all the non-universal properties of these bands are washed out,
hence only the topological properties persist.
acknowledgement: "N.L., T.G. and E.B. acknowledge support from the European Research
Council (ERC) under\r\nthe European Union Horizon 2020 Research and Innovation Programme
(Grant Agreement\r\nNo. 639172). T.G. was in part supported by an Aly Kaufman Fellowship
at the Technion. T.G.\r\nacknowledges funding from the Institute of Science and
Technology (IST) Austria, and from\r\nthe European Union’s Horizon 2020 research
and innovation programme under the Marie\r\nSkłodowska-Curie Grant Agreement No.
754411. N.L. acknowledges support from the People Programme (Marie Curie Actions)
of the European Unions Seventh Framework 546 Programme (FP7/20072013), under REA
Grant Agreement No. 631696, and by the Israeli Center\r\nof Research Excellence
(I-CORE) Circle of Light funded by the Israel Science Foundation (Grant\r\nNo. 1802/12).
M.R. gratefully acknowledges the support of the European Research Council\r\n(ERC)
under the European Union Horizon 2020 Research and Innovation Programme (Grant\r\nAgreement
No. 678862). M.R. acknowledges the support of the Villum Foundation. M.R. and\r\nE.B.
acknowledge support from CRC 183 of the Deutsche Forschungsgemeinschaft"
article_number: '015'
article_processing_charge: No
article_type: original
author:
- first_name: Tobias
full_name: Gulden, Tobias
id: 1083E038-9F73-11E9-A4B5-532AE6697425
last_name: Gulden
orcid: 0000-0001-6814-7541
- first_name: Erez
full_name: Berg, Erez
last_name: Berg
- first_name: Mark Spencer
full_name: Rudner, Mark Spencer
last_name: Rudner
- first_name: Netanel
full_name: Lindner, Netanel
last_name: Lindner
citation:
ama: Gulden T, Berg E, Rudner MS, Lindner N. Exponentially long lifetime of universal
quasi-steady states in topological Floquet pumps. SciPost Physics. 2020;9.
doi:10.21468/scipostphys.9.1.015
apa: Gulden, T., Berg, E., Rudner, M. S., & Lindner, N. (2020). Exponentially
long lifetime of universal quasi-steady states in topological Floquet pumps. SciPost
Physics. SciPost Foundation. https://doi.org/10.21468/scipostphys.9.1.015
chicago: Gulden, Tobias, Erez Berg, Mark Spencer Rudner, and Netanel Lindner. “Exponentially
Long Lifetime of Universal Quasi-Steady States in Topological Floquet Pumps.”
SciPost Physics. SciPost Foundation, 2020. https://doi.org/10.21468/scipostphys.9.1.015.
ieee: T. Gulden, E. Berg, M. S. Rudner, and N. Lindner, “Exponentially long lifetime
of universal quasi-steady states in topological Floquet pumps,” SciPost Physics,
vol. 9. SciPost Foundation, 2020.
ista: Gulden T, Berg E, Rudner MS, Lindner N. 2020. Exponentially long lifetime
of universal quasi-steady states in topological Floquet pumps. SciPost Physics.
9, 015.
mla: Gulden, Tobias, et al. “Exponentially Long Lifetime of Universal Quasi-Steady
States in Topological Floquet Pumps.” SciPost Physics, vol. 9, 015, SciPost
Foundation, 2020, doi:10.21468/scipostphys.9.1.015.
short: T. Gulden, E. Berg, M.S. Rudner, N. Lindner, SciPost Physics 9 (2020).
corr_author: '1'
date_created: 2020-08-04T13:04:15Z
date_published: 2020-07-29T00:00:00Z
date_updated: 2025-04-14T07:44:05Z
day: '29'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.21468/scipostphys.9.1.015
ec_funded: 1
external_id:
isi:
- '000557362300008'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2020-08-06T08:56:06Z
date_updated: 2020-08-06T08:56:06Z
file_id: '8202'
file_name: 2020_SciPostPhys_Gulden.pdf
file_size: 531137
relation: main_file
success: 1
file_date_updated: 2020-08-06T08:56:06Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: SciPost Physics
publication_identifier:
issn:
- 2542-4653
publication_status: published
publisher: SciPost Foundation
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exponentially long lifetime of universal quasi-steady states in topological
Floquet pumps
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...
---
_id: '8203'
abstract:
- lang: eng
text: Using inelastic cotunneling spectroscopy we observe a zero field splitting
within the spin triplet manifold of Ge hut wire quantum dots. The states with
spin ±1 in the confinement direction are energetically favored by up to 55 μeV
compared to the spin 0 triplet state because of the strong spin–orbit coupling.
The reported effect should be observable in a broad class of strongly confined
hole quantum-dot systems and might need to be considered when operating hole spin
qubits.
acknowledged_ssus:
- _id: NanoFab
- _id: M-Shop
acknowledgement: "We acknowledge G. Burkard, V. N. Golovach, C. Kloeffel, D.Loss,
P. Rabl, and M. Rancič ́ for helpful discussions. We\r\nfurther acknowledge T.
Adletzberger, J. Aguilera, T. Asenov, S. Bagiante, T. Menner, L. Shafeek, P. Taus,
P. Traunmüller, and D. Waldhausl for their invaluable assistance. This research
was supported by the Scientific Service Units of IST Austria through resources provided
by the MIBA Machine Shop and the nanofabrication facility, by the FWF-P 32235 project,
by the National Key R&D Program of China (2016YFA0301701, 2016YFA0300600), and by
the European Union’s Horizon 2020 research and innovation program under grant agreement
no. 862046. All data of this publication are available at 10.15479/AT:ISTA:7689."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
- first_name: Josip
full_name: Kukucka, Josip
id: 3F5D8856-F248-11E8-B48F-1D18A9856A87
last_name: Kukucka
- first_name: Lada
full_name: Vukušić, Lada
id: 31E9F056-F248-11E8-B48F-1D18A9856A87
last_name: Vukušić
orcid: 0000-0003-2424-8636
- first_name: Hannes
full_name: Watzinger, Hannes
id: 35DF8E50-F248-11E8-B48F-1D18A9856A87
last_name: Watzinger
- first_name: Fei
full_name: Gao, Fei
last_name: Gao
- first_name: Ting
full_name: Wang, Ting
last_name: Wang
orcid: 0000-0002-4619-9575
- first_name: Jian-Jun
full_name: Zhang, Jian-Jun
last_name: Zhang
- first_name: Karsten
full_name: Held, Karsten
last_name: Held
citation:
ama: Katsaros G, Kukucka J, Vukušić L, et al. Zero field splitting of heavy-hole
states in quantum dots. Nano Letters. 2020;20(7):5201-5206. doi:10.1021/acs.nanolett.0c01466
apa: Katsaros, G., Kukucka, J., Vukušić, L., Watzinger, H., Gao, F., Wang, T., …
Held, K. (2020). Zero field splitting of heavy-hole states in quantum dots. Nano
Letters. American Chemical Society. https://doi.org/10.1021/acs.nanolett.0c01466
chicago: Katsaros, Georgios, Josip Kukucka, Lada Vukušić, Hannes Watzinger, Fei
Gao, Ting Wang, Jian-Jun Zhang, and Karsten Held. “Zero Field Splitting of Heavy-Hole
States in Quantum Dots.” Nano Letters. American Chemical Society, 2020.
https://doi.org/10.1021/acs.nanolett.0c01466.
ieee: G. Katsaros et al., “Zero field splitting of heavy-hole states in quantum
dots,” Nano Letters, vol. 20, no. 7. American Chemical Society, pp. 5201–5206,
2020.
ista: Katsaros G, Kukucka J, Vukušić L, Watzinger H, Gao F, Wang T, Zhang J-J, Held
K. 2020. Zero field splitting of heavy-hole states in quantum dots. Nano Letters.
20(7), 5201–5206.
mla: Katsaros, Georgios, et al. “Zero Field Splitting of Heavy-Hole States in Quantum
Dots.” Nano Letters, vol. 20, no. 7, American Chemical Society, 2020, pp.
5201–06, doi:10.1021/acs.nanolett.0c01466.
short: G. Katsaros, J. Kukucka, L. Vukušić, H. Watzinger, F. Gao, T. Wang, J.-J.
Zhang, K. Held, Nano Letters 20 (2020) 5201–5206.
corr_author: '1'
date_created: 2020-08-06T09:25:04Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2025-04-15T08:39:16Z
day: '01'
ddc:
- '530'
department:
- _id: GeKa
doi: 10.1021/acs.nanolett.0c01466
ec_funded: 1
external_id:
isi:
- '000548893200066'
pmid:
- '32479090'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2020-08-06T09:35:37Z
date_updated: 2020-08-06T09:35:37Z
file_id: '8204'
file_name: 2020_NanoLetters_Katsaros.pdf
file_size: 3308906
relation: main_file
success: 1
file_date_updated: 2020-08-06T09:35:37Z
has_accepted_license: '1'
intvolume: ' 20'
isi: 1
issue: '7'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 5201-5206
pmid: 1
project:
- _id: 237B3DA4-32DE-11EA-91FC-C7463DDC885E
call_identifier: FWF
grant_number: P32235
name: Towards scalable hut wire quantum devices
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '862046'
name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
issn:
- 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
related_material:
record:
- id: '7689'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Zero field splitting of heavy-hole states in quantum dots
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 20
year: '2020'
...
---
_id: '8220'
abstract:
- lang: eng
text: Understanding to what extent stem cell potential is a cell-intrinsic property
or an emergent behavior coming from global tissue dynamics and geometry is a key
outstanding question of systems and stem cell biology. Here, we propose a theory
of stem cell dynamics as a stochastic competition for access to a spatially localized
niche, giving rise to a stochastic conveyor-belt model. Cell divisions produce
a steady cellular stream which advects cells away from the niche, while random
rearrangements enable cells away from the niche to be favorably repositioned.
Importantly, even when assuming that all cells in a tissue are molecularly equivalent,
we predict a common (“universal”) functional dependence of the long-term clonal
survival probability on distance from the niche, as well as the emergence of a
well-defined number of functional stem cells, dependent only on the rate of random
movements vs. mitosis-driven advection. We test the predictions of this theory
on datasets of pubertal mammary gland tips and embryonic kidney tips, as well
as homeostatic intestinal crypts. Importantly, we find good agreement for the
predicted functional dependency of the competition as a function of position,
and thus functional stem cell number in each organ. This argues for a key role
of positional fluctuations in dictating stem cell number and dynamics, and we
discuss the applicability of this theory to other settings.
acknowledgement: "We thank all members of the E.H., B.D.S., and J.v.R. groups for
stimulating discussions. This project was supported by\r\nthe European Research
Council (648804 to J.v.R. and 851288 to E.H.). It has also received support from
the CancerGenomics.nl (Netherlands Organization for Scientific Research) program
(J.v.R.) and the Doctor Josef Steiner Foundation (J.v.R). B.D.S. was supported by
Royal Society E. P. Abraham Research Professorship RP/R1/180165 and Wellcome Trust
Grant 098357/Z/12/Z."
article_processing_charge: No
article_type: original
author:
- first_name: Bernat
full_name: Corominas-Murtra, Bernat
id: 43BE2298-F248-11E8-B48F-1D18A9856A87
last_name: Corominas-Murtra
orcid: 0000-0001-9806-5643
- first_name: Colinda L.G.J.
full_name: Scheele, Colinda L.G.J.
last_name: Scheele
- first_name: Kasumi
full_name: Kishi, Kasumi
id: 3065DFC4-F248-11E8-B48F-1D18A9856A87
last_name: Kishi
orcid: 0000-0001-6060-4795
- first_name: Saskia I.J.
full_name: Ellenbroek, Saskia I.J.
last_name: Ellenbroek
- first_name: Benjamin D.
full_name: Simons, Benjamin D.
last_name: Simons
- first_name: Jacco
full_name: Van Rheenen, Jacco
last_name: Van Rheenen
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
citation:
ama: Corominas-Murtra B, Scheele CLGJ, Kishi K, et al. Stem cell lineage survival
as a noisy competition for niche access. Proceedings of the National Academy
of Sciences of the United States of America. 2020;117(29):16969-16975. doi:10.1073/pnas.1921205117
apa: Corominas-Murtra, B., Scheele, C. L. G. J., Kishi, K., Ellenbroek, S. I. J.,
Simons, B. D., Van Rheenen, J., & Hannezo, E. B. (2020). Stem cell lineage
survival as a noisy competition for niche access. Proceedings of the National
Academy of Sciences of the United States of America. National Academy of Sciences.
https://doi.org/10.1073/pnas.1921205117
chicago: Corominas-Murtra, Bernat, Colinda L.G.J. Scheele, Kasumi Kishi, Saskia
I.J. Ellenbroek, Benjamin D. Simons, Jacco Van Rheenen, and Edouard B Hannezo.
“Stem Cell Lineage Survival as a Noisy Competition for Niche Access.” Proceedings
of the National Academy of Sciences of the United States of America. National
Academy of Sciences, 2020. https://doi.org/10.1073/pnas.1921205117.
ieee: B. Corominas-Murtra et al., “Stem cell lineage survival as a noisy
competition for niche access,” Proceedings of the National Academy of Sciences
of the United States of America, vol. 117, no. 29. National Academy of Sciences,
pp. 16969–16975, 2020.
ista: Corominas-Murtra B, Scheele CLGJ, Kishi K, Ellenbroek SIJ, Simons BD, Van
Rheenen J, Hannezo EB. 2020. Stem cell lineage survival as a noisy competition
for niche access. Proceedings of the National Academy of Sciences of the United
States of America. 117(29), 16969–16975.
mla: Corominas-Murtra, Bernat, et al. “Stem Cell Lineage Survival as a Noisy Competition
for Niche Access.” Proceedings of the National Academy of Sciences of the United
States of America, vol. 117, no. 29, National Academy of Sciences, 2020, pp.
16969–75, doi:10.1073/pnas.1921205117.
short: B. Corominas-Murtra, C.L.G.J. Scheele, K. Kishi, S.I.J. Ellenbroek, B.D.
Simons, J. Van Rheenen, E.B. Hannezo, Proceedings of the National Academy of Sciences
of the United States of America 117 (2020) 16969–16975.
corr_author: '1'
date_created: 2020-08-09T22:00:52Z
date_published: 2020-07-21T00:00:00Z
date_updated: 2026-04-03T09:29:04Z
day: '21'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1073/pnas.1921205117
ec_funded: 1
external_id:
isi:
- '000553292900014'
pmid:
- '32611816'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2020-08-10T06:50:28Z
date_updated: 2020-08-10T06:50:28Z
file_id: '8223'
file_name: 2020_PNAS_Corominas.pdf
file_size: 1111604
relation: main_file
success: 1
file_date_updated: 2020-08-10T06:50:28Z
has_accepted_license: '1'
intvolume: ' 117'
isi: 1
issue: '29'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 16969-16975
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '851288'
name: Design Principles of Branching Morphogenesis
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
link:
- relation: press_release
url: https://ist.ac.at/en/news/order-from-noise/
scopus_import: '1'
status: public
title: Stem cell lineage survival as a noisy competition for niche access
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 117
year: '2020'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '8225'
abstract:
- lang: eng
text: Birch pollen allergy is among the most prevalent pollen allergies in Northern
and Central Europe. This IgE-mediated disease can be treated with allergen immunotherapy
(AIT), which typically gives rise to IgG antibodies inducing tolerance. Although
the main mechanisms of allergen immunotherapy (AIT) are known, questions regarding
possible Fc-mediated effects of IgG antibodies remain unanswered. This can mainly
be attributed to the unavailability of appropriate tools, i.e., well-characterised
recombinant antibodies (rAbs). We hereby aimed at providing human rAbs of several
classes for mechanistic studies and as possible candidates for passive immunotherapy.
We engineered IgE, IgG1, and IgG4 sharing the same variable region against the
major birch pollen allergen Bet v 1 using Polymerase Incomplete Primer Extension
(PIPE) cloning. We tested IgE functionality and IgG blocking capabilities using
appropriate model cell lines. In vitro studies showed IgE engagement with FcεRI
and CD23 and Bet v 1-dependent degranulation. Overall, we hereby present fully
functional, human IgE, IgG1, and IgG4 sharing the same variable region against
Bet v 1 and showcase possible applications in first mechanistic studies. Furthermore,
our IgG antibodies might be useful candidates for passive immunotherapy of birch
pollen allergy.
article_number: '5693'
article_processing_charge: No
article_type: original
author:
- first_name: Verena K.
full_name: Köhler, Verena K.
last_name: Köhler
orcid: 0000-0001-5581-398X
- first_name: Silvia
full_name: Crescioli, Silvia
last_name: Crescioli
orcid: 0000-0002-1909-5957
- first_name: Judit
full_name: Fazekas-Singer, Judit
id: 36432834-F248-11E8-B48F-1D18A9856A87
last_name: Fazekas-Singer
orcid: 0000-0002-8777-3502
- first_name: Heather J.
full_name: Bax, Heather J.
last_name: Bax
orcid: 0000-0003-0432-4160
- first_name: Gerhard
full_name: Hofer, Gerhard
last_name: Hofer
- first_name: Christina L.
full_name: Pranger, Christina L.
last_name: Pranger
- first_name: Karin
full_name: Hufnagl, Karin
last_name: Hufnagl
- first_name: Rodolfo
full_name: Bianchini, Rodolfo
last_name: Bianchini
orcid: 0000-0003-0351-6937
- first_name: Sabine
full_name: Flicker, Sabine
last_name: Flicker
orcid: 0000-0003-4768-8693
- first_name: Walter
full_name: Keller, Walter
last_name: Keller
orcid: 0000-0002-2261-958X
- first_name: Sophia N.
full_name: Karagiannis, Sophia N.
last_name: Karagiannis
orcid: 0000-0002-4100-7810
- first_name: Erika
full_name: Jensen-Jarolim, Erika
last_name: Jensen-Jarolim
orcid: 0000-0003-4019-5765
citation:
ama: 'Köhler VK, Crescioli S, Singer J, et al. Filling the antibody pipeline in
allergy: PIPE cloning of IgE, IgG1 and IgG4 against the major birch pollen allergen
Bet v 1. International Journal of Molecular Sciences. 2020;21(16). doi:10.3390/ijms21165693'
apa: 'Köhler, V. K., Crescioli, S., Singer, J., Bax, H. J., Hofer, G., Pranger,
C. L., … Jensen-Jarolim, E. (2020). Filling the antibody pipeline in allergy:
PIPE cloning of IgE, IgG1 and IgG4 against the major birch pollen allergen Bet
v 1. International Journal of Molecular Sciences. MDPI. https://doi.org/10.3390/ijms21165693'
chicago: 'Köhler, Verena K., Silvia Crescioli, Judit Singer, Heather J. Bax, Gerhard
Hofer, Christina L. Pranger, Karin Hufnagl, et al. “Filling the Antibody Pipeline
in Allergy: PIPE Cloning of IgE, IgG1 and IgG4 against the Major Birch Pollen
Allergen Bet v 1.” International Journal of Molecular Sciences. MDPI, 2020.
https://doi.org/10.3390/ijms21165693.'
ieee: 'V. K. Köhler et al., “Filling the antibody pipeline in allergy: PIPE
cloning of IgE, IgG1 and IgG4 against the major birch pollen allergen Bet v 1,”
International Journal of Molecular Sciences, vol. 21, no. 16. MDPI, 2020.'
ista: 'Köhler VK, Crescioli S, Singer J, Bax HJ, Hofer G, Pranger CL, Hufnagl K,
Bianchini R, Flicker S, Keller W, Karagiannis SN, Jensen-Jarolim E. 2020. Filling
the antibody pipeline in allergy: PIPE cloning of IgE, IgG1 and IgG4 against the
major birch pollen allergen Bet v 1. International Journal of Molecular Sciences.
21(16), 5693.'
mla: 'Köhler, Verena K., et al. “Filling the Antibody Pipeline in Allergy: PIPE
Cloning of IgE, IgG1 and IgG4 against the Major Birch Pollen Allergen Bet v 1.”
International Journal of Molecular Sciences, vol. 21, no. 16, 5693, MDPI,
2020, doi:10.3390/ijms21165693.'
short: V.K. Köhler, S. Crescioli, J. Singer, H.J. Bax, G. Hofer, C.L. Pranger, K.
Hufnagl, R. Bianchini, S. Flicker, W. Keller, S.N. Karagiannis, E. Jensen-Jarolim,
International Journal of Molecular Sciences 21 (2020).
date_created: 2020-08-10T11:47:29Z
date_published: 2020-08-08T00:00:00Z
date_updated: 2024-10-15T13:11:23Z
day: '08'
ddc:
- '570'
doi: 10.3390/ijms21165693
extern: '1'
external_id:
pmid:
- '32784509'
file:
- access_level: open_access
checksum: dac7ccef7cdcea9be292664d8c488425
content_type: application/pdf
creator: dernst
date_created: 2020-09-10T07:06:22Z
date_updated: 2020-09-10T07:06:22Z
file_id: '8356'
file_name: 2020_IntMolecSciences_Koehler.pdf
file_size: 2680908
relation: main_file
success: 1
file_date_updated: 2020-09-10T07:06:22Z
has_accepted_license: '1'
intvolume: ' 21'
issue: '16'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: International Journal of Molecular Sciences
publication_identifier:
issn:
- 1422-0067
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: 'Filling the antibody pipeline in allergy: PIPE cloning of IgE, IgG1 and IgG4
against the major birch pollen allergen Bet v 1'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
volume: 21
year: '2020'
...
---
OA_place: publisher
OA_type: hybrid
_id: '8226'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Jelena
full_name: Gotovina, Jelena
last_name: Gotovina
orcid: 0000-0003-1503-5276
- first_name: Rodolfo
full_name: Bianchini, Rodolfo
last_name: Bianchini
orcid: 0000-0003-0351-6937
- first_name: Judit
full_name: Fazekas-Singer, Judit
id: 36432834-F248-11E8-B48F-1D18A9856A87
last_name: Fazekas-Singer
orcid: 0000-0002-8777-3502
- first_name: Ina
full_name: Herrmann, Ina
last_name: Herrmann
orcid: 0000-0003-2772-9144
- first_name: Giulia
full_name: Pellizzari, Giulia
last_name: Pellizzari
orcid: 0000-0003-0387-1912
- first_name: Ian D.
full_name: Haidl, Ian D.
last_name: Haidl
orcid: 0000-0002-5301-0822
- first_name: Karin
full_name: Hufnagl, Karin
last_name: Hufnagl
orcid: 0000-0002-2288-2468
- first_name: Sophia N.
full_name: Karagiannis, Sophia N.
last_name: Karagiannis
orcid: 0000-0002-4100-7810
- first_name: Jean S.
full_name: Marshall, Jean S.
last_name: Marshall
orcid: 0000-0002-5642-1379
- first_name: Erika
full_name: Jensen‐Jarolim, Erika
last_name: Jensen‐Jarolim
orcid: 0000-0003-4019-5765
citation:
ama: Gotovina J, Bianchini R, Singer J, et al. Epinephrine drives human M2a allergic
macrophages to a regulatory phenotype reducing mast cell degranulation in vitro.
Allergy. 2020. doi:10.1111/all.14299
apa: Gotovina, J., Bianchini, R., Singer, J., Herrmann, I., Pellizzari, G., Haidl,
I. D., … Jensen‐Jarolim, E. (2020). Epinephrine drives human M2a allergic macrophages
to a regulatory phenotype reducing mast cell degranulation in vitro. Allergy.
Wiley. https://doi.org/10.1111/all.14299
chicago: Gotovina, Jelena, Rodolfo Bianchini, Judit Singer, Ina Herrmann, Giulia
Pellizzari, Ian D. Haidl, Karin Hufnagl, Sophia N. Karagiannis, Jean S. Marshall,
and Erika Jensen‐Jarolim. “Epinephrine Drives Human M2a Allergic Macrophages to
a Regulatory Phenotype Reducing Mast Cell Degranulation in Vitro.” Allergy.
Wiley, 2020. https://doi.org/10.1111/all.14299.
ieee: J. Gotovina et al., “Epinephrine drives human M2a allergic macrophages
to a regulatory phenotype reducing mast cell degranulation in vitro,” Allergy.
Wiley, 2020.
ista: Gotovina J, Bianchini R, Singer J, Herrmann I, Pellizzari G, Haidl ID, Hufnagl
K, Karagiannis SN, Marshall JS, Jensen‐Jarolim E. 2020. Epinephrine drives human
M2a allergic macrophages to a regulatory phenotype reducing mast cell degranulation
in vitro. Allergy.
mla: Gotovina, Jelena, et al. “Epinephrine Drives Human M2a Allergic Macrophages
to a Regulatory Phenotype Reducing Mast Cell Degranulation in Vitro.” Allergy,
Wiley, 2020, doi:10.1111/all.14299.
short: J. Gotovina, R. Bianchini, J. Singer, I. Herrmann, G. Pellizzari, I.D. Haidl,
K. Hufnagl, S.N. Karagiannis, J.S. Marshall, E. Jensen‐Jarolim, Allergy (2020).
date_created: 2020-08-10T11:50:30Z
date_published: 2020-04-04T00:00:00Z
date_updated: 2024-10-15T13:13:56Z
day: '04'
doi: 10.1111/all.14299
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/all.14299
month: '04'
oa: 1
oa_version: Published Version
publication: Allergy
publication_identifier:
issn:
- 0105-4538
- 1398-9995
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
status: public
title: Epinephrine drives human M2a allergic macrophages to a regulatory phenotype
reducing mast cell degranulation in vitro
type: journal_article
user_id: 0043cee0-e5fc-11ee-9736-f83bc23afbf0
year: '2020'
...
---
_id: '8254'
abstract:
- lang: eng
text: "Here are the research data underlying the publication \"Estimating inbreeding
and its effects in a long-term study of snapdragons (Antirrhinum majus)\". Further
information are summed up in the README document.\r\nThe files for this record
have been updated and are now found in the linked DOI https://doi.org/10.15479/AT:ISTA:9192."
article_processing_charge: No
author:
- first_name: Louise S
full_name: Arathoon, Louise S
id: 2CFCFF98-F248-11E8-B48F-1D18A9856A87
last_name: Arathoon
orcid: 0000-0003-1771-714X
citation:
ama: Arathoon LS. Estimating inbreeding and its effects in a long-term study of
snapdragons (Antirrhinum majus). 2020. doi:10.15479/AT:ISTA:8254
apa: Arathoon, L. S. (2020). Estimating inbreeding and its effects in a long-term
study of snapdragons (Antirrhinum majus). Institute of Science and Technology
Austria. https://doi.org/10.15479/AT:ISTA:8254
chicago: Arathoon, Louise S. “Estimating Inbreeding and Its Effects in a Long-Term
Study of Snapdragons (Antirrhinum Majus).” Institute of Science and Technology
Austria, 2020. https://doi.org/10.15479/AT:ISTA:8254.
ieee: L. S. Arathoon, “Estimating inbreeding and its effects in a long-term study
of snapdragons (Antirrhinum majus).” Institute of Science and Technology Austria,
2020.
ista: Arathoon LS. 2020. Estimating inbreeding and its effects in a long-term study
of snapdragons (Antirrhinum majus), Institute of Science and Technology Austria,
10.15479/AT:ISTA:8254.
mla: Arathoon, Louise S. Estimating Inbreeding and Its Effects in a Long-Term
Study of Snapdragons (Antirrhinum Majus). Institute of Science and Technology
Austria, 2020, doi:10.15479/AT:ISTA:8254.
short: L.S. Arathoon, (2020).
contributor:
- contributor_type: data_collector
first_name: Louise S
id: 2CFCFF98-F248-11E8-B48F-1D18A9856A87
last_name: Arathoon
- contributor_type: project_member
first_name: Parvathy
id: 455235B8-F248-11E8-B48F-1D18A9856A87
last_name: Surendranadh
- contributor_type: project_member
first_name: Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- contributor_type: project_member
first_name: David
id: 419049E2-F248-11E8-B48F-1D18A9856A87
last_name: Field
orcid: 0000-0002-4014-8478
- contributor_type: project_member
first_name: Melinda
id: 2C78037E-F248-11E8-B48F-1D18A9856A87
last_name: Pickup
orcid: 0000-0001-6118-0541
- contributor_type: project_member
first_name: Carina
id: 3B4A7CE2-F248-11E8-B48F-1D18A9856A87
last_name: Baskett
corr_author: '1'
date_created: 2020-08-12T12:49:23Z
date_published: 2020-08-18T00:00:00Z
date_updated: 2024-10-09T21:02:14Z
day: '18'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:8254
file:
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creator: dernst
date_created: 2020-08-18T08:03:23Z
date_updated: 2020-08-18T08:03:23Z
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file_name: Data_Rcode_MathematicaNB.zip
file_size: 5778420
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success: 1
file_date_updated: 2020-08-18T08:03:23Z
has_accepted_license: '1'
month: '08'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
record:
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relation: later_version
status: public
- id: '11321'
relation: later_version
status: public
status: public
title: Estimating inbreeding and its effects in a long-term study of snapdragons (Antirrhinum
majus)
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '8261'
abstract:
- lang: eng
text: Dentate gyrus granule cells (GCs) connect the entorhinal cortex to the hippocampal
CA3 region, but how they process spatial information remains enigmatic. To examine
the role of GCs in spatial coding, we measured excitatory postsynaptic potentials
(EPSPs) and action potentials (APs) in head-fixed mice running on a linear belt.
Intracellular recording from morphologically identified GCs revealed that most
cells were active, but activity level varied over a wide range. Whereas only ∼5%
of GCs showed spatially tuned spiking, ∼50% received spatially tuned input. Thus,
the GC population broadly encodes spatial information, but only a subset relays
this information to the CA3 network. Fourier analysis indicated that GCs received
conjunctive place-grid-like synaptic input, suggesting code conversion in single
neurons. GC firing was correlated with dendritic complexity and intrinsic excitability,
but not extrinsic excitatory input or dendritic cable properties. Thus, functional
maturation may control input-output transformation and spatial code conversion.
acknowledged_ssus:
- _id: M-Shop
- _id: ScienComp
- _id: PreCl
acknowledgement: This project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation program (grant
agreement 692692, P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung
(Z 312-B27, Wittgenstein award, P.J.). We thank Gyorgy Buzsáki, Jozsef Csicsvari,
Juan Ramirez Villegas, and Federico Stella for commenting on earlier versions of
this manuscript. We also thank Katie Bittner, Michael Brecht, Albert Lee, Jeffery
Magee, and Alejandro Pernía-Andrade for sharing expertise in in vivo patch-clamp
recording. We are grateful to Florian Marr for cell labeling, cell reconstruction,
and technical assistance; Ben Suter for helpful discussions; Christina Altmutter
for technical support; Eleftheria Kralli-Beller for manuscript editing; and Todor
Asenov (Machine Shop) for device construction. We also thank the Scientific Service
Units (SSUs) of IST Austria (Machine Shop, Scientific Computing, and Preclinical
Facility) for efficient support.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaomin
full_name: Zhang, Xiaomin
id: 423EC9C2-F248-11E8-B48F-1D18A9856A87
last_name: Zhang
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Zhang X, Schlögl A, Jonas PM. Selective routing of spatial information flow
from input to output in hippocampal granule cells. Neuron. 2020;107(6):1212-1225.
doi:10.1016/j.neuron.2020.07.006
apa: Zhang, X., Schlögl, A., & Jonas, P. M. (2020). Selective routing of spatial
information flow from input to output in hippocampal granule cells. Neuron.
Elsevier. https://doi.org/10.1016/j.neuron.2020.07.006
chicago: Zhang, Xiaomin, Alois Schlögl, and Peter M Jonas. “Selective Routing of
Spatial Information Flow from Input to Output in Hippocampal Granule Cells.” Neuron.
Elsevier, 2020. https://doi.org/10.1016/j.neuron.2020.07.006.
ieee: X. Zhang, A. Schlögl, and P. M. Jonas, “Selective routing of spatial information
flow from input to output in hippocampal granule cells,” Neuron, vol. 107,
no. 6. Elsevier, pp. 1212–1225, 2020.
ista: Zhang X, Schlögl A, Jonas PM. 2020. Selective routing of spatial information
flow from input to output in hippocampal granule cells. Neuron. 107(6), 1212–1225.
mla: Zhang, Xiaomin, et al. “Selective Routing of Spatial Information Flow from
Input to Output in Hippocampal Granule Cells.” Neuron, vol. 107, no. 6,
Elsevier, 2020, pp. 1212–25, doi:10.1016/j.neuron.2020.07.006.
short: X. Zhang, A. Schlögl, P.M. Jonas, Neuron 107 (2020) 1212–1225.
corr_author: '1'
date_created: 2020-08-14T09:36:05Z
date_published: 2020-09-23T00:00:00Z
date_updated: 2025-04-15T08:29:03Z
day: '23'
ddc:
- '570'
department:
- _id: PeJo
- _id: ScienComp
doi: 10.1016/j.neuron.2020.07.006
ec_funded: 1
external_id:
isi:
- '000579698700009'
pmid:
- '32763145'
file:
- access_level: open_access
checksum: 44a5960fc083a4cb3488d22224859fdc
content_type: application/pdf
creator: dernst
date_created: 2020-12-04T09:29:21Z
date_updated: 2020-12-04T09:29:21Z
file_id: '8920'
file_name: 2020_Neuron_Zhang.pdf
file_size: 3011120
relation: main_file
success: 1
file_date_updated: 2020-12-04T09:29:21Z
has_accepted_license: '1'
intvolume: ' 107'
isi: 1
issue: '6'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1212-1225
pmid: 1
project:
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '692692'
name: Biophysics and circuit function of a giant cortical glutamatergic synapse
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00312
name: Synaptic communication in neuronal microcircuits
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
link:
- description: News on IST Website
relation: press_release
url: https://ist.ac.at/en/news/the-bouncer-in-the-brain/
scopus_import: '1'
status: public
title: Selective routing of spatial information flow from input to output in hippocampal
granule cells
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 107
year: '2020'
...
---
_id: '8268'
abstract:
- lang: eng
text: 'Modern scientific instruments produce vast amounts of data, which can overwhelm
the processing ability of computer systems. Lossy compression of data is an intriguing
solution, but comes with its own drawbacks, such as potential signal loss, and
the need for careful optimization of the compression ratio. In this work, we focus
on a setting where this problem is especially acute: compressive sensing frameworks
for interferometry and medical imaging. We ask the following question: can the
precision of the data representation be lowered for all inputs, with recovery
guarantees and practical performance Our first contribution is a theoretical analysis
of the normalized Iterative Hard Thresholding (IHT) algorithm when all input data,
meaning both the measurement matrix and the observation vector are quantized aggressively.
We present a variant of low precision normalized IHT that, under mild conditions,
can still provide recovery guarantees. The second contribution is the application
of our quantization framework to radio astronomy and magnetic resonance imaging.
We show that lowering the precision of the data can significantly accelerate image
recovery. We evaluate our approach on telescope data and samples of brain images
using CPU and FPGA implementations achieving up to a 9x speedup with negligible
loss of recovery quality.'
acknowledgement: The authors would like to thank Dr. Michiel Brentjens at the Netherlands
Institute for Radio Astronomy (ASTRON) for providing radio interferometer data and
Dr. Josip Marjanovic and Dr. Franciszek Hennel at the Magnetic Resonance Technology
of ETH Zurich for providing their insights on the experiments. CZ and the DS3Lab
gratefully acknowledge the support from the Swiss Data Science Center, Alibaba,
Google Focused Research Awards, Huawei, MeteoSwiss, Oracle Labs, Swisscom, Zurich
Insurance, Chinese Scholarship Council, and the Department of Computer Science at
ETH Zurich.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nezihe Merve
full_name: Gurel, Nezihe Merve
last_name: Gurel
- first_name: Kaan
full_name: Kara, Kaan
last_name: Kara
- first_name: Alen
full_name: Stojanov, Alen
last_name: Stojanov
- first_name: Tyler
full_name: Smith, Tyler
last_name: Smith
- first_name: Thomas
full_name: Lemmin, Thomas
last_name: Lemmin
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Markus
full_name: Puschel, Markus
last_name: Puschel
- first_name: Ce
full_name: Zhang, Ce
last_name: Zhang
citation:
ama: 'Gurel NM, Kara K, Stojanov A, et al. Compressive sensing using iterative hard
thresholding with low precision data representation: Theory and applications.
IEEE Transactions on Signal Processing. 2020;68:4268-4282. doi:10.1109/TSP.2020.3010355'
apa: 'Gurel, N. M., Kara, K., Stojanov, A., Smith, T., Lemmin, T., Alistarh, D.-A.,
… Zhang, C. (2020). Compressive sensing using iterative hard thresholding with
low precision data representation: Theory and applications. IEEE Transactions
on Signal Processing. IEEE. https://doi.org/10.1109/TSP.2020.3010355'
chicago: 'Gurel, Nezihe Merve, Kaan Kara, Alen Stojanov, Tyler Smith, Thomas Lemmin,
Dan-Adrian Alistarh, Markus Puschel, and Ce Zhang. “Compressive Sensing Using
Iterative Hard Thresholding with Low Precision Data Representation: Theory and
Applications.” IEEE Transactions on Signal Processing. IEEE, 2020. https://doi.org/10.1109/TSP.2020.3010355.'
ieee: 'N. M. Gurel et al., “Compressive sensing using iterative hard thresholding
with low precision data representation: Theory and applications,” IEEE Transactions
on Signal Processing, vol. 68. IEEE, pp. 4268–4282, 2020.'
ista: 'Gurel NM, Kara K, Stojanov A, Smith T, Lemmin T, Alistarh D-A, Puschel M,
Zhang C. 2020. Compressive sensing using iterative hard thresholding with low
precision data representation: Theory and applications. IEEE Transactions on Signal
Processing. 68, 4268–4282.'
mla: 'Gurel, Nezihe Merve, et al. “Compressive Sensing Using Iterative Hard Thresholding
with Low Precision Data Representation: Theory and Applications.” IEEE Transactions
on Signal Processing, vol. 68, IEEE, 2020, pp. 4268–82, doi:10.1109/TSP.2020.3010355.'
short: N.M. Gurel, K. Kara, A. Stojanov, T. Smith, T. Lemmin, D.-A. Alistarh, M.
Puschel, C. Zhang, IEEE Transactions on Signal Processing 68 (2020) 4268–4282.
date_created: 2020-08-16T22:00:56Z
date_published: 2020-07-20T00:00:00Z
date_updated: 2025-07-10T11:55:10Z
day: '20'
department:
- _id: DaAl
doi: 10.1109/TSP.2020.3010355
external_id:
arxiv:
- '1802.04907'
isi:
- '000562044500001'
intvolume: ' 68'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.04907
month: '07'
oa: 1
oa_version: Preprint
page: 4268-4282
publication: IEEE Transactions on Signal Processing
publication_identifier:
eissn:
- 1941-0476
issn:
- 1053-587X
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Compressive sensing using iterative hard thresholding with low precision data
representation: Theory and applications'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 68
year: '2020'
...
---
OA_place: publisher
OA_type: free access
_id: '8271'
acknowledgement: We thank Dr. Gai Huang for his comments and help. We apologize to
authors whose work could not be cited due to space limitation. No conflict of interest
declared.
article_processing_charge: No
article_type: original
author:
- first_name: Peng
full_name: He, Peng
last_name: He
- first_name: Yuzhou
full_name: Zhang, Yuzhou
id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
last_name: Zhang
orcid: 0000-0003-2627-6956
- first_name: Guanghui
full_name: Xiao, Guanghui
last_name: Xiao
citation:
ama: He P, Zhang Y, Xiao G. Origin of a subgenome and genome evolution of allotetraploid
cotton species. Molecular Plant. 2020;13(9):1238-1240. doi:10.1016/j.molp.2020.07.006
apa: He, P., Zhang, Y., & Xiao, G. (2020). Origin of a subgenome and genome
evolution of allotetraploid cotton species. Molecular Plant. Elsevier.
https://doi.org/10.1016/j.molp.2020.07.006
chicago: He, Peng, Yuzhou Zhang, and Guanghui Xiao. “Origin of a Subgenome and Genome
Evolution of Allotetraploid Cotton Species.” Molecular Plant. Elsevier,
2020. https://doi.org/10.1016/j.molp.2020.07.006.
ieee: P. He, Y. Zhang, and G. Xiao, “Origin of a subgenome and genome evolution
of allotetraploid cotton species,” Molecular Plant, vol. 13, no. 9. Elsevier,
pp. 1238–1240, 2020.
ista: He P, Zhang Y, Xiao G. 2020. Origin of a subgenome and genome evolution of
allotetraploid cotton species. Molecular Plant. 13(9), 1238–1240.
mla: He, Peng, et al. “Origin of a Subgenome and Genome Evolution of Allotetraploid
Cotton Species.” Molecular Plant, vol. 13, no. 9, Elsevier, 2020, pp. 1238–40,
doi:10.1016/j.molp.2020.07.006.
short: P. He, Y. Zhang, G. Xiao, Molecular Plant 13 (2020) 1238–1240.
date_created: 2020-08-16T22:00:57Z
date_published: 2020-09-07T00:00:00Z
date_updated: 2026-06-18T19:32:01Z
day: '07'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.molp.2020.07.006
external_id:
isi:
- '000566895400007'
pmid:
- '32688032'
intvolume: ' 13'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.molp.2020.07.006
month: '09'
oa: 1
oa_version: Published Version
page: 1238-1240
pmid: 1
publication: Molecular Plant
publication_identifier:
eissn:
- 1752-9867
issn:
- 1674-2052
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Origin of a subgenome and genome evolution of allotetraploid cotton species
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2020'
...
---
_id: '8272'
abstract:
- lang: eng
text: We study turn-based stochastic zero-sum games with lexicographic preferences
over reachability and safety objectives. Stochastic games are standard models
in control, verification, and synthesis of stochastic reactive systems that exhibit
both randomness as well as angelic and demonic non-determinism. Lexicographic
order allows to consider multiple objectives with a strict preference order over
the satisfaction of the objectives. To the best of our knowledge, stochastic games
with lexicographic objectives have not been studied before. We establish determinacy
of such games and present strategy and computational complexity results. For strategy
complexity, we show that lexicographically optimal strategies exist that are deterministic
and memory is only required to remember the already satisfied and violated objectives.
For a constant number of objectives, we show that the relevant decision problem
is in NP∩coNP , matching the current known bound for single objectives; and
in general the decision problem is PSPACE -hard and can be solved in NEXPTIME∩coNEXPTIME
. We present an algorithm that computes the lexicographically optimal strategies
via a reduction to computation of optimal strategies in a sequence of single-objectives
games. We have implemented our algorithm and report experimental results on various
case studies.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Joost P
full_name: Katoen, Joost P
id: 4524F760-F248-11E8-B48F-1D18A9856A87
last_name: Katoen
orcid: 0000-0002-6143-1926
- first_name: Maximilian
full_name: Weininger, Maximilian
last_name: Weininger
- first_name: Tobias
full_name: Winkler, Tobias
last_name: Winkler
citation:
ama: 'Chatterjee K, Katoen JP, Weininger M, Winkler T. Stochastic games with lexicographic
reachability-safety objectives. In: International Conference on Computer Aided
Verification. Vol 12225. Springer Nature; 2020:398-420. doi:10.1007/978-3-030-53291-8_21'
apa: Chatterjee, K., Katoen, J. P., Weininger, M., & Winkler, T. (2020). Stochastic
games with lexicographic reachability-safety objectives. In International Conference
on Computer Aided Verification (Vol. 12225, pp. 398–420). Springer Nature.
https://doi.org/10.1007/978-3-030-53291-8_21
chicago: Chatterjee, Krishnendu, Joost P Katoen, Maximilian Weininger, and Tobias
Winkler. “Stochastic Games with Lexicographic Reachability-Safety Objectives.”
In International Conference on Computer Aided Verification, 12225:398–420.
Springer Nature, 2020. https://doi.org/10.1007/978-3-030-53291-8_21.
ieee: K. Chatterjee, J. P. Katoen, M. Weininger, and T. Winkler, “Stochastic games
with lexicographic reachability-safety objectives,” in International Conference
on Computer Aided Verification, 2020, vol. 12225, pp. 398–420.
ista: 'Chatterjee K, Katoen JP, Weininger M, Winkler T. 2020. Stochastic games with
lexicographic reachability-safety objectives. International Conference on Computer
Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 12225, 398–420.'
mla: Chatterjee, Krishnendu, et al. “Stochastic Games with Lexicographic Reachability-Safety
Objectives.” International Conference on Computer Aided Verification, vol.
12225, Springer Nature, 2020, pp. 398–420, doi:10.1007/978-3-030-53291-8_21.
short: K. Chatterjee, J.P. Katoen, M. Weininger, T. Winkler, in:, International
Conference on Computer Aided Verification, Springer Nature, 2020, pp. 398–420.
conference:
name: 'CAV: Computer Aided Verification'
date_created: 2020-08-16T22:00:58Z
date_published: 2020-07-14T00:00:00Z
date_updated: 2026-04-16T09:31:14Z
day: '14'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-030-53291-8_21
ec_funded: 1
external_id:
arxiv:
- '2005.04018'
isi:
- '000695272500021'
file:
- access_level: open_access
checksum: 093d4788d7d5b2ce0ffe64fbe7820043
content_type: application/pdf
creator: dernst
date_created: 2020-08-17T11:32:44Z
date_updated: 2020-08-17T11:32:44Z
file_id: '8276'
file_name: 2020_LNCS_CAV_Chatterjee.pdf
file_size: 625056
relation: main_file
success: 1
file_date_updated: 2020-08-17T11:32:44Z
has_accepted_license: '1'
intvolume: ' 12225'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 398-420
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
publication: International Conference on Computer Aided Verification
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783030532901'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '12738'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Stochastic games with lexicographic reachability-safety objectives
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 12225
year: '2020'
...
---
_id: '8284'
abstract:
- lang: eng
text: Multiple resistance and pH adaptation (Mrp) antiporters are multi-subunit
Na+ (or K+)/H+ exchangers representing an ancestor of many essential redox-driven
proton pumps, such as respiratory complex I. The mechanism of coupling between
ion or electron transfer and proton translocation in this large protein family
is unknown. Here, we present the structure of the Mrp complex from Anoxybacillus
flavithermus solved by cryo-EM at 3.0 Å resolution. It is a dimer of seven-subunit
protomers with 50 trans-membrane helices each. Surface charge distribution within
each monomer is remarkably asymmetric, revealing probable proton and sodium translocation
pathways. On the basis of the structure we propose a mechanism where the coupling
between sodium and proton translocation is facilitated by a series of electrostatic
interactions between a cation and key charged residues. This mechanism is likely
to be applicable to the entire family of redox proton pumps, where electron transfer
to substrates replaces cation movements.
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
acknowledgement: This research was supported by the Scientific Service Units (SSU)
of IST Austria through resources provided by the Electron Microscopy Facility (EMF),
the Life Science Facility (LSF) and the IST high-performance computing cluster.
We thank Dr Victor-Valentin Hodirnau and Daniel Johann Gütl from IST Austria for
assistance with collecting cryo-EM data. We thank Prof. Masahiro Ito (Graduate School
of Life Sciences, Toyo University, Japan) for a kind provision of plasmid DNA encoding
Mrp from A. flavithermus WK1. JS is a recipient of a DOC Fellowship of the Austrian
Academy of Sciences at the Institute of Science and Technology, Austria.
article_number: e59407
article_processing_charge: No
article_type: original
author:
- first_name: Julia
full_name: Steiner, Julia
id: 3BB67EB0-F248-11E8-B48F-1D18A9856A87
last_name: Steiner
orcid: 0000-0003-0493-3775
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Steiner J, Sazanov LA. Structure and mechanism of the Mrp complex, an ancient
cation/proton antiporter. eLife. 2020;9. doi:10.7554/eLife.59407
apa: Steiner, J., & Sazanov, L. A. (2020). Structure and mechanism of the Mrp
complex, an ancient cation/proton antiporter. ELife. eLife Sciences Publications.
https://doi.org/10.7554/eLife.59407
chicago: Steiner, Julia, and Leonid A Sazanov. “Structure and Mechanism of the Mrp
Complex, an Ancient Cation/Proton Antiporter.” ELife. eLife Sciences Publications,
2020. https://doi.org/10.7554/eLife.59407.
ieee: J. Steiner and L. A. Sazanov, “Structure and mechanism of the Mrp complex,
an ancient cation/proton antiporter,” eLife, vol. 9. eLife Sciences Publications,
2020.
ista: Steiner J, Sazanov LA. 2020. Structure and mechanism of the Mrp complex, an
ancient cation/proton antiporter. eLife. 9, e59407.
mla: Steiner, Julia, and Leonid A. Sazanov. “Structure and Mechanism of the Mrp
Complex, an Ancient Cation/Proton Antiporter.” ELife, vol. 9, e59407, eLife
Sciences Publications, 2020, doi:10.7554/eLife.59407.
short: J. Steiner, L.A. Sazanov, ELife 9 (2020).
date_created: 2020-08-24T06:24:04Z
date_published: 2020-07-31T00:00:00Z
date_updated: 2026-04-08T07:23:36Z
day: '31'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.7554/eLife.59407
external_id:
isi:
- '000562123600001'
pmid:
- '32735215'
file:
- access_level: open_access
checksum: b3656d14d5ddbb9d26e3074eea2d0c15
content_type: application/pdf
creator: cziletti
date_created: 2020-08-24T13:31:53Z
date_updated: 2020-08-24T13:31:53Z
file_id: '8289'
file_name: 2020_eLife_Steiner.pdf
file_size: 7320493
relation: main_file
success: 1
file_date_updated: 2020-08-24T13:31:53Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26169496-B435-11E9-9278-68D0E5697425
grant_number: '24741'
name: Revealing the functional mechanism of Mrp antiporter, an ancestor of complex
I
publication: eLife
publication_identifier:
eissn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/mystery-of-giant-proton-pump-solved/
record:
- id: '8353'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 9
year: '2020'
...