---
_id: '6527'
abstract:
- lang: eng
  text: "A memory-hard function (MHF) ƒn with parameter n can be computed in sequential
    time and space n. Simultaneously, a high amortized parallel area-time complexity
    (aAT) is incurred per evaluation. In practice, MHFs are used to limit the rate
    at which an adversary (using a custom computational device) can evaluate a security
    sensitive function that still occasionally needs to be evaluated by honest users
    (using an off-the-shelf general purpose device). The most prevalent examples of
    such sensitive functions are Key Derivation Functions (KDFs) and password hashing
    algorithms where rate limits help mitigate off-line dictionary attacks. As the
    honest users' inputs to these functions are often (low-entropy) passwords special
    attention is given to a class of side-channel resistant MHFs called iMHFs.\r\n\r\nEssentially
    all iMHFs can be viewed as some mode of operation (making n calls to some round
    function) given by a directed acyclic graph (DAG) with very low indegree. Recently,
    a combinatorial property of a DAG has been identified (called \"depth-robustness\")
    which results in good provable security for an iMHF based on that DAG. Depth-robust
    DAGs have also proven useful in other cryptographic applications. Unfortunately,
    up till now, all known very depth-robust DAGs are impractically complicated and
    little is known about their exact (i.e. non-asymptotic) depth-robustness both
    in theory and in practice.\r\n\r\nIn this work we build and analyze (both formally
    and empirically) several exceedingly simple and efficient to navigate practical
    DAGs for use in iMHFs and other applications. For each DAG we:\r\n*Prove that
    their depth-robustness is asymptotically maximal.\r\n*Prove bounds of at least
    3 orders of magnitude better on their exact depth-robustness compared to known
    bounds for other practical iMHF.\r\n*Implement and empirically evaluate their
    depth-robustness and aAT against a variety of state-of-the art (and several new)
    depth-reduction and low aAT attacks. \r\nWe find that, against all attacks, the
    new DAGs perform significantly better in practice than Argon2i, the most widely
    deployed iMHF in practice.\r\n\r\nAlong the way we also improve the best known
    empirical attacks on the aAT of Argon2i by implementing and testing several heuristic
    versions of a (hitherto purely theoretical) depth-reduction attack. Finally, we
    demonstrate practicality of our constructions by modifying the Argon2i code base
    to use one of the new high aAT DAGs. Experimental benchmarks on a standard off-the-shelf
    CPU show that the new modifications do not adversely affect the impressive throughput
    of Argon2i (despite seemingly enjoying significantly higher aAT).\r\n"
article_processing_charge: No
author:
- first_name: Joel F
  full_name: Alwen, Joel F
  id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
  last_name: Alwen
- first_name: Jeremiah
  full_name: Blocki, Jeremiah
  last_name: Blocki
- first_name: Ben
  full_name: Harsha, Ben
  last_name: Harsha
citation:
  ama: 'Alwen JF, Blocki J, Harsha B. Practical graphs for optimal side-channel resistant
    memory-hard functions. In: <i>Proceedings of the 2017 ACM SIGSAC Conference on
    Computer and Communications Security</i>. ACM; 2017:1001-1017. doi:<a href="https://doi.org/10.1145/3133956.3134031">10.1145/3133956.3134031</a>'
  apa: 'Alwen, J. F., Blocki, J., &#38; Harsha, B. (2017). Practical graphs for optimal
    side-channel resistant memory-hard functions. In <i>Proceedings of the 2017 ACM
    SIGSAC Conference on Computer and Communications Security</i> (pp. 1001–1017).
    Dallas, TX, USA: ACM. <a href="https://doi.org/10.1145/3133956.3134031">https://doi.org/10.1145/3133956.3134031</a>'
  chicago: Alwen, Joel F, Jeremiah Blocki, and Ben Harsha. “Practical Graphs for Optimal
    Side-Channel Resistant Memory-Hard Functions.” In <i>Proceedings of the 2017 ACM
    SIGSAC Conference on Computer and Communications Security</i>, 1001–17. ACM, 2017.
    <a href="https://doi.org/10.1145/3133956.3134031">https://doi.org/10.1145/3133956.3134031</a>.
  ieee: J. F. Alwen, J. Blocki, and B. Harsha, “Practical graphs for optimal side-channel
    resistant memory-hard functions,” in <i>Proceedings of the 2017 ACM SIGSAC Conference
    on Computer and Communications Security</i>, Dallas, TX, USA, 2017, pp. 1001–1017.
  ista: 'Alwen JF, Blocki J, Harsha B. 2017. Practical graphs for optimal side-channel
    resistant memory-hard functions. Proceedings of the 2017 ACM SIGSAC Conference
    on Computer and Communications Security. CCS: Conference on Computer and Communications
    Security, 1001–1017.'
  mla: Alwen, Joel F., et al. “Practical Graphs for Optimal Side-Channel Resistant
    Memory-Hard Functions.” <i>Proceedings of the 2017 ACM SIGSAC Conference on Computer
    and Communications Security</i>, ACM, 2017, pp. 1001–17, doi:<a href="https://doi.org/10.1145/3133956.3134031">10.1145/3133956.3134031</a>.
  short: J.F. Alwen, J. Blocki, B. Harsha, in:, Proceedings of the 2017 ACM SIGSAC
    Conference on Computer and Communications Security, ACM, 2017, pp. 1001–1017.
conference:
  end_date: 2017-11-03
  location: Dallas, TX, USA
  name: 'CCS: Conference on Computer and Communications Security'
  start_date: 2017-10-30
date_created: 2019-06-06T13:21:29Z
date_published: 2017-10-30T00:00:00Z
date_updated: 2025-09-18T10:40:38Z
day: '30'
department:
- _id: KrPi
doi: 10.1145/3133956.3134031
ec_funded: 1
external_id:
  isi:
  - '000440307700063'
fulldoi: https://doi.org/10.1145/3133956.3134031
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2017/443
month: '10'
oa: 1
oa_version: Submitted Version
page: 1001-1017
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: Proceedings of the 2017 ACM SIGSAC Conference on Computer and Communications
  Security
publication_identifier:
  isbn:
  - '9781450349468'
publication_status: published
publisher: ACM
quality_controlled: '1'
scopus_import: '1'
status: public
title: Practical graphs for optimal side-channel resistant memory-hard functions
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2017'
...
---
_id: '653'
abstract:
- lang: eng
  text: The extent of heterogeneity among driver gene mutations present in naturally
    occurring metastases - that is, treatment-naive metastatic disease - is largely
    unknown. To address this issue, we carried out 60× whole-genome sequencing of
    26 metastases from four patients with pancreatic cancer. We found that identical
    mutations in known driver genes were present in every metastatic lesion for each
    patient studied. Passenger gene mutations, which do not have known or predicted
    functional consequences, accounted for all intratumoral heterogeneity. Even with
    respect to these passenger mutations, our analysis suggests that the genetic similarity
    among the founding cells of metastases was higher than that expected for any two
    cells randomly taken from a normal tissue. The uniformity of known driver gene
    mutations among metastases in the same patient has critical and encouraging implications
    for the success of future targeted therapies in advanced-stage disease.
acknowledgement: 'We thank the Memorial Sloan Kettering Cancer Center Molecular Cytology
  core facility for immunohistochemistry staining. This work was supported by Office
  of Naval Research grant N00014-16-1-2914, the Bill and Melinda Gates Foundation
  (OPP1148627), and a gift from B. Wu and E. Larson (M.A.N.), National Institutes
  of Health grants CA179991 (C.A.I.-D. and I.B.), F31 CA180682 (A.P.M.-M.), CA43460
  (B.V.), and P50 CA62924, the Monastra Foundation, the Virginia and D.K. Ludwig Fund
  for Cancer Research, the Lustgarten Foundation for Pancreatic Cancer Research, the
  Sol Goldman Center for Pancreatic Cancer Research, the Sol Goldman Sequencing Center,
  ERC Start grant 279307: Graph Games (J.G.R., D.K., and C.K.), Austrian Science Fund
  (FWF) grant P23499-N23 (J.G.R., D.K., and C.K.), and FWF NFN grant S11407-N23 RiSE/SHiNE
  (J.G.R., D.K., and C.K.).'
article_processing_charge: No
article_type: original
author:
- first_name: Alvin
  full_name: Makohon Moore, Alvin
  last_name: Makohon Moore
- first_name: Ming
  full_name: Zhang, Ming
  last_name: Zhang
- first_name: Johannes
  full_name: Reiter, Johannes
  id: 4A918E98-F248-11E8-B48F-1D18A9856A87
  last_name: Reiter
  orcid: 0000-0002-0170-7353
- first_name: Ivana
  full_name: Božić, Ivana
  last_name: Božić
- first_name: Benjamin
  full_name: Allen, Benjamin
  last_name: Allen
- first_name: Deepanjan
  full_name: Kundu, Deepanjan
  id: 1d4c0f4f-e8a3-11ec-a351-e36772758c45
  last_name: Kundu
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Fay
  full_name: Wong, Fay
  last_name: Wong
- first_name: Yuchen
  full_name: Jiao, Yuchen
  last_name: Jiao
- first_name: Zachary
  full_name: Kohutek, Zachary
  last_name: Kohutek
- first_name: Jungeui
  full_name: Hong, Jungeui
  last_name: Hong
- first_name: Marc
  full_name: Attiyeh, Marc
  last_name: Attiyeh
- first_name: Breanna
  full_name: Javier, Breanna
  last_name: Javier
- first_name: Laura
  full_name: Wood, Laura
  last_name: Wood
- first_name: Ralph
  full_name: Hruban, Ralph
  last_name: Hruban
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
- first_name: Nickolas
  full_name: Papadopoulos, Nickolas
  last_name: Papadopoulos
- first_name: Kenneth
  full_name: Kinzler, Kenneth
  last_name: Kinzler
- first_name: Bert
  full_name: Vogelstein, Bert
  last_name: Vogelstein
- first_name: Christine
  full_name: Iacobuzio Donahue, Christine
  last_name: Iacobuzio Donahue
citation:
  ama: Makohon Moore A, Zhang M, Reiter J, et al. Limited heterogeneity of known driver
    gene mutations among the metastases of individual patients with pancreatic cancer.
    <i>Nature Genetics</i>. 2017;49(3):358-366. doi:<a href="https://doi.org/10.1038/ng.3764">10.1038/ng.3764</a>
  apa: Makohon Moore, A., Zhang, M., Reiter, J., Božić, I., Allen, B., Kundu, D.,
    … Iacobuzio Donahue, C. (2017). Limited heterogeneity of known driver gene mutations
    among the metastases of individual patients with pancreatic cancer. <i>Nature
    Genetics</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ng.3764">https://doi.org/10.1038/ng.3764</a>
  chicago: Makohon Moore, Alvin, Ming Zhang, Johannes Reiter, Ivana Božić, Benjamin
    Allen, Deepanjan Kundu, Krishnendu Chatterjee, et al. “Limited Heterogeneity of
    Known Driver Gene Mutations among the Metastases of Individual Patients with Pancreatic
    Cancer.” <i>Nature Genetics</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/ng.3764">https://doi.org/10.1038/ng.3764</a>.
  ieee: A. Makohon Moore <i>et al.</i>, “Limited heterogeneity of known driver gene
    mutations among the metastases of individual patients with pancreatic cancer,”
    <i>Nature Genetics</i>, vol. 49, no. 3. Nature Publishing Group, pp. 358–366,
    2017.
  ista: Makohon Moore A, Zhang M, Reiter J, Božić I, Allen B, Kundu D, Chatterjee
    K, Wong F, Jiao Y, Kohutek Z, Hong J, Attiyeh M, Javier B, Wood L, Hruban R, Nowak
    M, Papadopoulos N, Kinzler K, Vogelstein B, Iacobuzio Donahue C. 2017. Limited
    heterogeneity of known driver gene mutations among the metastases of individual
    patients with pancreatic cancer. Nature Genetics. 49(3), 358–366.
  mla: Makohon Moore, Alvin, et al. “Limited Heterogeneity of Known Driver Gene Mutations
    among the Metastases of Individual Patients with Pancreatic Cancer.” <i>Nature
    Genetics</i>, vol. 49, no. 3, Nature Publishing Group, 2017, pp. 358–66, doi:<a
    href="https://doi.org/10.1038/ng.3764">10.1038/ng.3764</a>.
  short: A. Makohon Moore, M. Zhang, J. Reiter, I. Božić, B. Allen, D. Kundu, K. Chatterjee,
    F. Wong, Y. Jiao, Z. Kohutek, J. Hong, M. Attiyeh, B. Javier, L. Wood, R. Hruban,
    M. Nowak, N. Papadopoulos, K. Kinzler, B. Vogelstein, C. Iacobuzio Donahue, Nature
    Genetics 49 (2017) 358–366.
date_created: 2018-12-11T11:47:43Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2025-09-11T07:12:56Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1038/ng.3764
ec_funded: 1
external_id:
  isi:
  - '000394917800009'
  pmid:
  - '28092682'
file:
- access_level: open_access
  checksum: e442dc3b7420a36ec805e9bb45cc1a2e
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-19T08:13:50Z
  date_updated: 2020-07-14T12:47:33Z
  file_id: '7050'
  file_name: 2017_NatureGenetics_Makohon.pdf
  file_size: 908099
  relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
fulldoi: https://doi.org/10.1038/ng.3764
has_accepted_license: '1'
intvolume: '        49'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 358 - 366
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: Nature Genetics
publication_identifier:
  issn:
  - 1061-4036
publication_status: published
publisher: Nature Publishing Group
publist_id: '7092'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Limited heterogeneity of known driver gene mutations among the metastases of
  individual patients with pancreatic cancer
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 49
year: '2017'
...
---
_id: '654'
abstract:
- lang: eng
  text: In November 2016, developmental biologists, synthetic biologists and engineers
    gathered in Paris for a meeting called ‘Engineering the embryo’. The participants
    shared an interest in exploring how synthetic systems can reveal new principles
    of embryonic development, and how the in vitro manipulation and modeling of development
    using stem cells can be used to integrate ideas and expertise from physics, developmental
    biology and tissue engineering. As we review here, the conference pinpointed some
    of the challenges arising at the intersection of these fields, along with great
    enthusiasm for finding new approaches and collaborations.
article_processing_charge: No
author:
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
- first_name: Nicolas
  full_name: Rivron, Nicolas
  last_name: Rivron
citation:
  ama: Kicheva A, Rivron N. Creating to understand – developmental biology meets engineering
    in Paris. <i>Development</i>. 2017;144(5):733-736. doi:<a href="https://doi.org/10.1242/dev.144915">10.1242/dev.144915</a>
  apa: Kicheva, A., &#38; Rivron, N. (2017). Creating to understand – developmental
    biology meets engineering in Paris. <i>Development</i>. Company of Biologists.
    <a href="https://doi.org/10.1242/dev.144915">https://doi.org/10.1242/dev.144915</a>
  chicago: Kicheva, Anna, and Nicolas Rivron. “Creating to Understand – Developmental
    Biology Meets Engineering in Paris.” <i>Development</i>. Company of Biologists,
    2017. <a href="https://doi.org/10.1242/dev.144915">https://doi.org/10.1242/dev.144915</a>.
  ieee: A. Kicheva and N. Rivron, “Creating to understand – developmental biology
    meets engineering in Paris,” <i>Development</i>, vol. 144, no. 5. Company of Biologists,
    pp. 733–736, 2017.
  ista: Kicheva A, Rivron N. 2017. Creating to understand – developmental biology
    meets engineering in Paris. Development. 144(5), 733–736.
  mla: Kicheva, Anna, and Nicolas Rivron. “Creating to Understand – Developmental
    Biology Meets Engineering in Paris.” <i>Development</i>, vol. 144, no. 5, Company
    of Biologists, 2017, pp. 733–36, doi:<a href="https://doi.org/10.1242/dev.144915">10.1242/dev.144915</a>.
  short: A. Kicheva, N. Rivron, Development 144 (2017) 733–736.
corr_author: '1'
date_created: 2018-12-11T11:47:44Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2026-04-16T09:59:52Z
day: '01'
ddc:
- '571'
department:
- _id: AnKi
doi: 10.1242/dev.144915
ec_funded: 1
external_id:
  isi:
  - '000395650100001'
file:
- access_level: open_access
  checksum: eef22a0f42a55b232cb2d1188a2322cb
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:20Z
  date_updated: 2020-07-14T12:47:33Z
  file_id: '5139'
  file_name: IST-2018-987-v1+1_2017_KichevaRivron__Creating_to.pdf
  file_size: 228206
  relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
fulldoi: https://doi.org/10.1242/dev.144915
has_accepted_license: '1'
intvolume: '       144'
isi: 1
issue: '5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 733 - 736
project:
- _id: B6FC0238-B512-11E9-945C-1524E6697425
  call_identifier: H2020
  grant_number: '680037'
  name: Coordination of Patterning And Growth In the Spinal Cord
publication: Development
publication_identifier:
  issn:
  - 0950-1991
publication_status: published
publisher: Company of Biologists
publist_id: '7089'
pubrep_id: '987'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Creating to understand – developmental biology meets engineering in Paris
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 144
year: '2017'
...
---
_id: '655'
abstract:
- lang: eng
  text: 'The bacterial flagellum is a self-assembling nanomachine. The external flagellar
    filament, several times longer than a bacterial cell body, is made of a few tens
    of thousands subunits of a single protein: flagellin. A fundamental problem concerns
    the molecular mechanism of how the flagellum grows outside the cell, where no
    discernible energy source is available. Here, we monitored the dynamic assembly
    of individual flagella using in situ labelling and real-time immunostaining of
    elongating flagellar filaments. We report that the rate of flagellum growth, initially
    ~1,700 amino acids per second, decreases with length and that the previously proposed
    chain mechanism does not contribute to the filament elongation dynamics. Inhibition
    of the proton motive force-dependent export apparatus revealed a major contribution
    of substrate injection in driving filament elongation. The combination of experimental
    and mathematical evidence demonstrates that a simple, injection-diffusion mechanism
    controls bacterial flagella growth outside the cell.'
article_number: e23136
article_processing_charge: No
author:
- first_name: Thibaud
  full_name: Renault, Thibaud
  last_name: Renault
- first_name: Anthony
  full_name: Abraham, Anthony
  last_name: Abraham
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Guillaume
  full_name: Paradis, Guillaume
  last_name: Paradis
- first_name: Simon
  full_name: Rainville, Simon
  last_name: Rainville
- first_name: Emmanuelle
  full_name: Charpentier, Emmanuelle
  last_name: Charpentier
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
- first_name: Yuhai
  full_name: Tu, Yuhai
  last_name: Tu
- first_name: Keiichi
  full_name: Namba, Keiichi
  last_name: Namba
- first_name: James
  full_name: Keener, James
  last_name: Keener
- first_name: Tohru
  full_name: Minamino, Tohru
  last_name: Minamino
- first_name: Marc
  full_name: Erhardt, Marc
  last_name: Erhardt
citation:
  ama: Renault T, Abraham A, Bergmiller T, et al. Bacterial flagella grow through
    an injection diffusion mechanism. <i>eLife</i>. 2017;6. doi:<a href="https://doi.org/10.7554/eLife.23136">10.7554/eLife.23136</a>
  apa: Renault, T., Abraham, A., Bergmiller, T., Paradis, G., Rainville, S., Charpentier,
    E., … Erhardt, M. (2017). Bacterial flagella grow through an injection diffusion
    mechanism. <i>ELife</i>. eLife Sciences Publications. <a href="https://doi.org/10.7554/eLife.23136">https://doi.org/10.7554/eLife.23136</a>
  chicago: Renault, Thibaud, Anthony Abraham, Tobias Bergmiller, Guillaume Paradis,
    Simon Rainville, Emmanuelle Charpentier, Calin C Guet, et al. “Bacterial Flagella
    Grow through an Injection Diffusion Mechanism.” <i>ELife</i>. eLife Sciences Publications,
    2017. <a href="https://doi.org/10.7554/eLife.23136">https://doi.org/10.7554/eLife.23136</a>.
  ieee: T. Renault <i>et al.</i>, “Bacterial flagella grow through an injection diffusion
    mechanism,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.
  ista: Renault T, Abraham A, Bergmiller T, Paradis G, Rainville S, Charpentier E,
    Guet CC, Tu Y, Namba K, Keener J, Minamino T, Erhardt M. 2017. Bacterial flagella
    grow through an injection diffusion mechanism. eLife. 6, e23136.
  mla: Renault, Thibaud, et al. “Bacterial Flagella Grow through an Injection Diffusion
    Mechanism.” <i>ELife</i>, vol. 6, e23136, eLife Sciences Publications, 2017, doi:<a
    href="https://doi.org/10.7554/eLife.23136">10.7554/eLife.23136</a>.
  short: T. Renault, A. Abraham, T. Bergmiller, G. Paradis, S. Rainville, E. Charpentier,
    C.C. Guet, Y. Tu, K. Namba, J. Keener, T. Minamino, M. Erhardt, ELife 6 (2017).
date_created: 2018-12-11T11:47:44Z
date_published: 2017-03-06T00:00:00Z
date_updated: 2025-09-11T07:11:19Z
day: '06'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.7554/eLife.23136
external_id:
  isi:
  - '000398680700001'
file:
- access_level: open_access
  checksum: 39e1c3e82ddac83a30422fa72fa1a383
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:53Z
  date_updated: 2020-07-14T12:47:33Z
  file_id: '4716'
  file_name: IST-2017-904-v1+1_elife-23136-v2.pdf
  file_size: 5520359
  relation: main_file
- access_level: open_access
  checksum: a6d542253028f52e00aa29739ddffe8f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:54Z
  date_updated: 2020-07-14T12:47:33Z
  file_id: '4717'
  file_name: IST-2017-904-v1+2_elife-23136-figures-v2.pdf
  file_size: 11242920
  relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
fulldoi: https://doi.org/10.7554/eLife.23136
has_accepted_license: '1'
intvolume: '         6'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '03'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
publist_id: '7082'
pubrep_id: '904'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bacterial flagella grow through an injection diffusion mechanism
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2017'
...
---
_id: '657'
abstract:
- lang: eng
  text: Plant organs are typically organized into three main tissue layers. The middle
    ground tissue layer comprises the majority of the plant body and serves a wide
    range of functions, including photosynthesis, selective nutrient uptake and storage,
    and gravity sensing. Ground tissue patterning and maintenance in Arabidopsis are
    controlled by a well-established gene network revolving around the key regulator
    SHORT-ROOT (SHR). In contrast, it is completely unknown how ground tissue identity
    is first specified from totipotent precursor cells in the embryo. The plant signaling
    molecule auxin, acting through AUXIN RESPONSE FACTOR (ARF) transcription factors,
    is critical for embryo patterning. The auxin effector ARF5/MONOPTEROS (MP) acts
    both cell-autonomously and noncell-autonomously to control embryonic vascular
    tissue formation and root initiation, respectively. Here we show that auxin response
    and ARF activity cell-autonomously control the asymmetric division of the first
    ground tissue cells. By identifying embryonic target genes, we show that MP transcriptionally
    initiates the ground tissue lineage and acts upstream of the regulatory network
    that controls ground tissue patterning and maintenance. Strikingly, whereas the
    SHR network depends on MP, this MP function is, at least in part, SHR independent.
    Our study therefore identifies auxin response as a regulator of ground tissue
    specification in the embryonic root, and reveals that ground tissue initiation
    and maintenance use different regulators and mechanisms. Moreover, our data provide
    a framework for the simultaneous formation of multiple cell types by the same
    transcriptional regulator.
article_processing_charge: No
author:
- first_name: Barbara
  full_name: Möller, Barbara
  last_name: Möller
- first_name: Colette
  full_name: Ten Hove, Colette
  last_name: Ten Hove
- first_name: Daoquan
  full_name: Xiang, Daoquan
  last_name: Xiang
- first_name: Nerys
  full_name: Williams, Nerys
  last_name: Williams
- first_name: Lorena
  full_name: López, Lorena
  last_name: López
- first_name: Saiko
  full_name: Yoshida, Saiko
  id: 2E46069C-F248-11E8-B48F-1D18A9856A87
  last_name: Yoshida
- first_name: Margot
  full_name: Smit, Margot
  last_name: Smit
- first_name: Raju
  full_name: Datla, Raju
  last_name: Datla
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
citation:
  ama: Möller B, Ten Hove C, Xiang D, et al. Auxin response cell autonomously controls
    ground tissue initiation in the early arabidopsis embryo. <i>PNAS</i>. 2017;114(12):E2533-E2539.
    doi:<a href="https://doi.org/10.1073/pnas.1616493114">10.1073/pnas.1616493114</a>
  apa: Möller, B., Ten Hove, C., Xiang, D., Williams, N., López, L., Yoshida, S.,
    … Weijers, D. (2017). Auxin response cell autonomously controls ground tissue
    initiation in the early arabidopsis embryo. <i>PNAS</i>. National Academy of Sciences.
    <a href="https://doi.org/10.1073/pnas.1616493114">https://doi.org/10.1073/pnas.1616493114</a>
  chicago: Möller, Barbara, Colette Ten Hove, Daoquan Xiang, Nerys Williams, Lorena
    López, Saiko Yoshida, Margot Smit, Raju Datla, and Dolf Weijers. “Auxin Response
    Cell Autonomously Controls Ground Tissue Initiation in the Early Arabidopsis Embryo.”
    <i>PNAS</i>. National Academy of Sciences, 2017. <a href="https://doi.org/10.1073/pnas.1616493114">https://doi.org/10.1073/pnas.1616493114</a>.
  ieee: B. Möller <i>et al.</i>, “Auxin response cell autonomously controls ground
    tissue initiation in the early arabidopsis embryo,” <i>PNAS</i>, vol. 114, no.
    12. National Academy of Sciences, pp. E2533–E2539, 2017.
  ista: Möller B, Ten Hove C, Xiang D, Williams N, López L, Yoshida S, Smit M, Datla
    R, Weijers D. 2017. Auxin response cell autonomously controls ground tissue initiation
    in the early arabidopsis embryo. PNAS. 114(12), E2533–E2539.
  mla: Möller, Barbara, et al. “Auxin Response Cell Autonomously Controls Ground Tissue
    Initiation in the Early Arabidopsis Embryo.” <i>PNAS</i>, vol. 114, no. 12, National
    Academy of Sciences, 2017, pp. E2533–39, doi:<a href="https://doi.org/10.1073/pnas.1616493114">10.1073/pnas.1616493114</a>.
  short: B. Möller, C. Ten Hove, D. Xiang, N. Williams, L. López, S. Yoshida, M. Smit,
    R. Datla, D. Weijers, PNAS 114 (2017) E2533–E2539.
date_created: 2018-12-11T11:47:45Z
date_published: 2017-03-21T00:00:00Z
date_updated: 2025-09-11T07:09:58Z
day: '21'
department:
- _id: JiFr
doi: 10.1073/pnas.1616493114
external_id:
  isi:
  - '000396893600033'
  pmid:
  - '28265057'
fulldoi: https://doi.org/10.1073/pnas.1616493114
intvolume: '       114'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373392/
month: '03'
oa: 1
oa_version: Submitted Version
page: E2533 - E2539
pmid: 1
publication: PNAS
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '7076'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin response cell autonomously controls ground tissue initiation in the early
  arabidopsis embryo
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 114
year: '2017'
...
---
_id: '658'
abstract:
- lang: eng
  text: 'With the accelerated development of robot technologies, control becomes one
    of the central themes of research. In traditional approaches, the controller,
    by its internal functionality, finds appropriate actions on the basis of specific
    objectives for the task at hand. While very successful in many applications, self-organized
    control schemes seem to be favored in large complex systems with unknown dynamics
    or which are difficult to model. Reasons are the expected scalability, robustness,
    and resilience of self-organizing systems. The paper presents a self-learning
    neurocontroller based on extrinsic differential plasticity introduced recently,
    applying it to an anthropomorphic musculoskeletal robot arm with attached objects
    of unknown physical dynamics. The central finding of the paper is the following
    effect: by the mere feedback through the internal dynamics of the object, the
    robot is learning to relate each of the objects with a very specific sensorimotor
    pattern. Specifically, an attached pendulum pilots the arm into a circular motion,
    a half-filled bottle produces axis oriented shaking behavior, a wheel is getting
    rotated, and wiping patterns emerge automatically in a table-plus-brush setting.
    By these object-specific dynamical patterns, the robot may be said to recognize
    the object''s identity, or in other words, it discovers dynamical affordances
    of objects. Furthermore, when including hand coordinates obtained from a camera,
    a dedicated hand-eye coordination self-organizes spontaneously. These phenomena
    are discussed from a specific dynamical system perspective. Central is the dedicated
    working regime at the border to instability with its potentially infinite reservoir
    of (limit cycle) attractors &quot;waiting&quot; to be excited. Besides converging
    toward one of these attractors, variate behavior is also arising from a self-induced
    attractor morphing driven by the learning rule. We claim that experimental investigations
    with this anthropomorphic, self-learning robot not only generate interesting and
    potentially useful behaviors, but may also help to better understand what subjective
    human muscle feelings are, how they can be rooted in sensorimotor patterns, and
    how these concepts may feed back on robotics.'
article_number: '00008'
article_processing_charge: Yes
author:
- first_name: Ralf
  full_name: Der, Ralf
  last_name: Der
- first_name: Georg S
  full_name: Martius, Georg S
  id: 3A276B68-F248-11E8-B48F-1D18A9856A87
  last_name: Martius
citation:
  ama: Der R, Martius GS. Self organized behavior generation for musculoskeletal robots.
    <i>Frontiers in Neurorobotics</i>. 2017;11(MAR). doi:<a href="https://doi.org/10.3389/fnbot.2017.00008">10.3389/fnbot.2017.00008</a>
  apa: Der, R., &#38; Martius, G. S. (2017). Self organized behavior generation for
    musculoskeletal robots. <i>Frontiers in Neurorobotics</i>. Frontiers Research
    Foundation. <a href="https://doi.org/10.3389/fnbot.2017.00008">https://doi.org/10.3389/fnbot.2017.00008</a>
  chicago: Der, Ralf, and Georg S Martius. “Self Organized Behavior Generation for
    Musculoskeletal Robots.” <i>Frontiers in Neurorobotics</i>. Frontiers Research
    Foundation, 2017. <a href="https://doi.org/10.3389/fnbot.2017.00008">https://doi.org/10.3389/fnbot.2017.00008</a>.
  ieee: R. Der and G. S. Martius, “Self organized behavior generation for musculoskeletal
    robots,” <i>Frontiers in Neurorobotics</i>, vol. 11, no. MAR. Frontiers Research
    Foundation, 2017.
  ista: Der R, Martius GS. 2017. Self organized behavior generation for musculoskeletal
    robots. Frontiers in Neurorobotics. 11(MAR), 00008.
  mla: Der, Ralf, and Georg S. Martius. “Self Organized Behavior Generation for Musculoskeletal
    Robots.” <i>Frontiers in Neurorobotics</i>, vol. 11, no. MAR, 00008, Frontiers
    Research Foundation, 2017, doi:<a href="https://doi.org/10.3389/fnbot.2017.00008">10.3389/fnbot.2017.00008</a>.
  short: R. Der, G.S. Martius, Frontiers in Neurorobotics 11 (2017).
corr_author: '1'
date_created: 2018-12-11T11:47:45Z
date_published: 2017-03-16T00:00:00Z
date_updated: 2025-09-11T07:10:33Z
day: '16'
ddc:
- '006'
department:
- _id: ChLa
- _id: GaTk
doi: 10.3389/fnbot.2017.00008
ec_funded: 1
external_id:
  isi:
  - '000396303400001'
file:
- access_level: open_access
  checksum: b1bc43f96d1df3313c03032c2a46388d
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:18:49Z
  date_updated: 2020-07-14T12:47:33Z
  file_id: '5371'
  file_name: IST-2017-903-v1+1_fnbot-11-00008.pdf
  file_size: 8439566
  relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
fulldoi: https://doi.org/10.3389/fnbot.2017.00008
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: MAR
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Frontiers in Neurorobotics
publication_identifier:
  issn:
  - 1662-5218
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '7078'
pubrep_id: '903'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self organized behavior generation for musculoskeletal robots
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 11
year: '2017'
...
---
_id: '659'
abstract:
- lang: eng
  text: Migration frequently involves Rac-mediated protrusion of lamellipodia, formed
    by Arp2/3 complex-dependent branching thought to be crucial for force generation
    and stability of these networks. The formins FMNL2 and FMNL3 are Cdc42 effectors
    targeting to the lamellipodium tip and shown here to nucleate and elongate actin
    filaments with complementary activities in vitro. In migrating B16-F1 melanoma
    cells, both formins contribute to the velocity of lamellipodium protrusion. Loss
    of FMNL2/3 function in melanoma cells and fibroblasts reduces lamellipodial width,
    actin filament density and -bundling, without changing patterns of Arp2/3 complex
    incorporation. Strikingly, in melanoma cells, FMNL2/3 gene inactivation almost
    completely abolishes protrusion forces exerted by lamellipodia and modifies their
    ultrastructural organization. Consistently, CRISPR/Cas-mediated depletion of FMNL2/3
    in fibroblasts reduces both migration and capability of cells to move against
    viscous media. Together, we conclude that force generation in lamellipodia strongly
    depends on FMNL formin activity, operating in addition to Arp2/3 complex-dependent
    filament branching.
article_number: '14832'
article_processing_charge: No
author:
- first_name: Frieda
  full_name: Kage, Frieda
  last_name: Kage
- first_name: Moritz
  full_name: Winterhoff, Moritz
  last_name: Winterhoff
- first_name: Vanessa
  full_name: Dimchev, Vanessa
  last_name: Dimchev
- first_name: Jan
  full_name: Müller, Jan
  id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
  last_name: Müller
- first_name: Tobias
  full_name: Thalheim, Tobias
  last_name: Thalheim
- first_name: Anika
  full_name: Freise, Anika
  last_name: Freise
- first_name: Stefan
  full_name: Brühmann, Stefan
  last_name: Brühmann
- first_name: Jana
  full_name: Kollasser, Jana
  last_name: Kollasser
- first_name: Jennifer
  full_name: Block, Jennifer
  last_name: Block
- first_name: Georgi A
  full_name: Dimchev, Georgi A
  last_name: Dimchev
- first_name: Matthias
  full_name: Geyer, Matthias
  last_name: Geyer
- first_name: Hams
  full_name: Schnittler, Hams
  last_name: Schnittler
- first_name: Cord
  full_name: Brakebusch, Cord
  last_name: Brakebusch
- first_name: Theresia
  full_name: Stradal, Theresia
  last_name: Stradal
- first_name: Marie
  full_name: Carlier, Marie
  last_name: Carlier
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Josef
  full_name: Käs, Josef
  last_name: Käs
- first_name: Jan
  full_name: Faix, Jan
  last_name: Faix
- first_name: Klemens
  full_name: Rottner, Klemens
  last_name: Rottner
citation:
  ama: Kage F, Winterhoff M, Dimchev V, et al. FMNL formins boost lamellipodial force
    generation. <i>Nature Communications</i>. 2017;8. doi:<a href="https://doi.org/10.1038/ncomms14832">10.1038/ncomms14832</a>
  apa: Kage, F., Winterhoff, M., Dimchev, V., Müller, J., Thalheim, T., Freise, A.,
    … Rottner, K. (2017). FMNL formins boost lamellipodial force generation. <i>Nature
    Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms14832">https://doi.org/10.1038/ncomms14832</a>
  chicago: Kage, Frieda, Moritz Winterhoff, Vanessa Dimchev, Jan Müller, Tobias Thalheim,
    Anika Freise, Stefan Brühmann, et al. “FMNL Formins Boost Lamellipodial Force
    Generation.” <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/ncomms14832">https://doi.org/10.1038/ncomms14832</a>.
  ieee: F. Kage <i>et al.</i>, “FMNL formins boost lamellipodial force generation,”
    <i>Nature Communications</i>, vol. 8. Nature Publishing Group, 2017.
  ista: Kage F, Winterhoff M, Dimchev V, Müller J, Thalheim T, Freise A, Brühmann
    S, Kollasser J, Block J, Dimchev GA, Geyer M, Schnittler H, Brakebusch C, Stradal
    T, Carlier M, Sixt MK, Käs J, Faix J, Rottner K. 2017. FMNL formins boost lamellipodial
    force generation. Nature Communications. 8, 14832.
  mla: Kage, Frieda, et al. “FMNL Formins Boost Lamellipodial Force Generation.” <i>Nature
    Communications</i>, vol. 8, 14832, Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/ncomms14832">10.1038/ncomms14832</a>.
  short: F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S.
    Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch,
    T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications
    8 (2017).
date_created: 2018-12-11T11:47:46Z
date_published: 2017-03-22T00:00:00Z
date_updated: 2025-09-11T07:09:28Z
day: '22'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1038/ncomms14832
external_id:
  isi:
  - '000396993700001'
file:
- access_level: open_access
  checksum: dae30190291c3630e8102d8714a8d23e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:21Z
  date_updated: 2020-07-14T12:47:34Z
  file_id: '5072'
  file_name: IST-2017-902-v1+1_Kage_et_al-2017-Nature_Communications.pdf
  file_size: 9523746
  relation: main_file
file_date_updated: 2020-07-14T12:47:34Z
fulldoi: https://doi.org/10.1038/ncomms14832
has_accepted_license: '1'
intvolume: '         8'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Nature Publishing Group
publist_id: '7075'
pubrep_id: '902'
quality_controlled: '1'
scopus_import: '1'
status: public
title: FMNL formins boost lamellipodial force generation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2017'
...
---
_id: '660'
abstract:
- lang: eng
  text: Growing microtubules are protected from depolymerization by the presence of
    a GTP or GDP/Pi cap. End-binding proteins of the EB1 family bind to the stabilizing
    cap, allowing monitoring of its size in real time. The cap size has been shown
    to correlate with instantaneous microtubule stability. Here we have quantitatively
    characterized the properties of cap size fluctuations during steadystate growth
    and have developed a theory predicting their timescale and amplitude from the
    kinetics of microtubule growth and cap maturation. In contrast to growth speed
    fluctuations, cap size fluctuations show a characteristic timescale, which is
    defined by the lifetime of the cap sites. Growth fluctuations affect the amplitude
    of cap size fluctuations; however, cap size does not affect growth speed, indicating
    that microtubules are far from instability during most of their time of growth.
    Our theory provides the basis for a quantitative understanding of microtubule
    stability fluctuations during steady-state growth.
acknowledgement: We thank Philippe Cluzel for helpful discussions and Gunnar Pruessner
  for data analysis advice. This work was supported by the Francis Crick Institute,
  which receives its core funding from Cancer Research UK Grant FC001163, Medical
  Research Council Grant FC001163, and Wellcome Trust Grant FC001163. This work was
  also supported by European Research Council Advanced Grant Project 323042 (to C.D.
  and T.S.).
article_processing_charge: No
author:
- first_name: Jamie
  full_name: Rickman, Jamie
  last_name: Rickman
- first_name: Christian F
  full_name: Düllberg, Christian F
  id: 459064DC-F248-11E8-B48F-1D18A9856A87
  last_name: Düllberg
  orcid: 0000-0001-6335-9748
- first_name: Nicholas
  full_name: Cade, Nicholas
  last_name: Cade
- first_name: Lewis
  full_name: Griffin, Lewis
  last_name: Griffin
- first_name: Thomas
  full_name: Surrey, Thomas
  last_name: Surrey
citation:
  ama: Rickman J, Düllberg CF, Cade N, Griffin L, Surrey T. Steady state EB cap size
    fluctuations are determined by stochastic microtubule growth and maturation. <i>PNAS</i>.
    2017;114(13):3427-3432. doi:<a href="https://doi.org/10.1073/pnas.1620274114">10.1073/pnas.1620274114</a>
  apa: Rickman, J., Düllberg, C. F., Cade, N., Griffin, L., &#38; Surrey, T. (2017).
    Steady state EB cap size fluctuations are determined by stochastic microtubule
    growth and maturation. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1620274114">https://doi.org/10.1073/pnas.1620274114</a>
  chicago: Rickman, Jamie, Christian F Düllberg, Nicholas Cade, Lewis Griffin, and
    Thomas Surrey. “Steady State EB Cap Size Fluctuations Are Determined by Stochastic
    Microtubule Growth and Maturation.” <i>PNAS</i>. National Academy of Sciences,
    2017. <a href="https://doi.org/10.1073/pnas.1620274114">https://doi.org/10.1073/pnas.1620274114</a>.
  ieee: J. Rickman, C. F. Düllberg, N. Cade, L. Griffin, and T. Surrey, “Steady state
    EB cap size fluctuations are determined by stochastic microtubule growth and maturation,”
    <i>PNAS</i>, vol. 114, no. 13. National Academy of Sciences, pp. 3427–3432, 2017.
  ista: Rickman J, Düllberg CF, Cade N, Griffin L, Surrey T. 2017. Steady state EB
    cap size fluctuations are determined by stochastic microtubule growth and maturation.
    PNAS. 114(13), 3427–3432.
  mla: Rickman, Jamie, et al. “Steady State EB Cap Size Fluctuations Are Determined
    by Stochastic Microtubule Growth and Maturation.” <i>PNAS</i>, vol. 114, no. 13,
    National Academy of Sciences, 2017, pp. 3427–32, doi:<a href="https://doi.org/10.1073/pnas.1620274114">10.1073/pnas.1620274114</a>.
  short: J. Rickman, C.F. Düllberg, N. Cade, L. Griffin, T. Surrey, PNAS 114 (2017)
    3427–3432.
date_created: 2018-12-11T11:47:46Z
date_published: 2017-03-28T00:00:00Z
date_updated: 2025-09-11T07:08:20Z
day: '28'
department:
- _id: MaLo
doi: 10.1073/pnas.1620274114
external_id:
  isi:
  - '000397607300065'
  pmid:
  - '28280102'
fulldoi: https://doi.org/10.1073/pnas.1620274114
intvolume: '       114'
isi: 1
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380103/
month: '03'
oa: 1
oa_version: Submitted Version
page: 3427 - 3432
pmid: 1
publication: PNAS
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '7073'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Steady state EB cap size fluctuations are determined by stochastic microtubule
  growth and maturation
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 114
year: '2017'
...
---
_id: '662'
abstract:
- lang: eng
  text: 'We report a direct-numerical-simulation study of the Taylor-Couette flow
    in the quasi-Keplerian regime at shear Reynolds numbers up to (105). Quasi-Keplerian
    rotating flow has been investigated for decades as a simplified model system to
    study the origin of turbulence in accretion disks that is not fully understood.
    The flow in this study is axially periodic and thus the experimental end-wall
    effects on the stability of the flow are avoided. Using optimal linear perturbations
    as initial conditions, our simulations find no sustained turbulence: the strong
    initial perturbations distort the velocity profile and trigger turbulence that
    eventually decays.'
article_number: '044107'
article_processing_charge: No
arxiv: 1
author:
- first_name: Liang
  full_name: Shi, Liang
  last_name: Shi
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
- first_name: Markus
  full_name: Rampp, Markus
  last_name: Rampp
- first_name: Marc
  full_name: Avila, Marc
  last_name: Avila
citation:
  ama: Shi L, Hof B, Rampp M, Avila M. Hydrodynamic turbulence in quasi Keplerian
    rotating flows. <i>Physics of Fluids</i>. 2017;29(4). doi:<a href="https://doi.org/10.1063/1.4981525">10.1063/1.4981525</a>
  apa: Shi, L., Hof, B., Rampp, M., &#38; Avila, M. (2017). Hydrodynamic turbulence
    in quasi Keplerian rotating flows. <i>Physics of Fluids</i>. American Institute
    of Physics. <a href="https://doi.org/10.1063/1.4981525">https://doi.org/10.1063/1.4981525</a>
  chicago: Shi, Liang, Björn Hof, Markus Rampp, and Marc Avila. “Hydrodynamic Turbulence
    in Quasi Keplerian Rotating Flows.” <i>Physics of Fluids</i>. American Institute
    of Physics, 2017. <a href="https://doi.org/10.1063/1.4981525">https://doi.org/10.1063/1.4981525</a>.
  ieee: L. Shi, B. Hof, M. Rampp, and M. Avila, “Hydrodynamic turbulence in quasi
    Keplerian rotating flows,” <i>Physics of Fluids</i>, vol. 29, no. 4. American
    Institute of Physics, 2017.
  ista: Shi L, Hof B, Rampp M, Avila M. 2017. Hydrodynamic turbulence in quasi Keplerian
    rotating flows. Physics of Fluids. 29(4), 044107.
  mla: Shi, Liang, et al. “Hydrodynamic Turbulence in Quasi Keplerian Rotating Flows.”
    <i>Physics of Fluids</i>, vol. 29, no. 4, 044107, American Institute of Physics,
    2017, doi:<a href="https://doi.org/10.1063/1.4981525">10.1063/1.4981525</a>.
  short: L. Shi, B. Hof, M. Rampp, M. Avila, Physics of Fluids 29 (2017).
date_created: 2018-12-11T11:47:47Z
date_published: 2017-04-01T00:00:00Z
date_updated: 2025-09-11T07:06:55Z
day: '01'
department:
- _id: BjHo
doi: 10.1063/1.4981525
external_id:
  arxiv:
  - '1703.01714'
  isi:
  - '000400384100022'
fulldoi: https://doi.org/10.1063/1.4981525
intvolume: '        29'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1703.01714
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 2511D90C-B435-11E9-9278-68D0E5697425
  grant_number: SFB 963  TP A8
  name: Astrophysical instability of currents and turbulences
publication: Physics of Fluids
publication_identifier:
  issn:
  - 1070-6631
publication_status: published
publisher: American Institute of Physics
publist_id: '7072'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Hydrodynamic turbulence in quasi Keplerian rotating flows
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 29
year: '2017'
...
---
_id: '663'
abstract:
- lang: eng
  text: 'In this paper, we propose an approach to automatically compute invariant
    clusters for nonlinear semialgebraic hybrid systems. An invariant cluster for
    an ordinary differential equation (ODE) is a multivariate polynomial invariant
    g(u→, x→) = 0, parametric in u→, which can yield an infinite number of concrete
    invariants by assigning different values to u→ so that every trajectory of the
    system can be overapproximated precisely by the intersection of a group of concrete
    invariants. For semialgebraic systems, which involve ODEs with multivariate polynomial
    right-hand sides, given a template multivariate polynomial g(u→, x→), an invariant
    cluster can be obtained by first computing the remainder of the Lie derivative
    of g(u→, x→) divided by g(u→, x→) and then solving the system of polynomial equations
    obtained from the coefficients of the remainder. Based on invariant clusters and
    sum-of-squares (SOS) programming, we present a new method for the safety verification
    of hybrid systems. Experiments on nonlinear benchmark systems from biology and
    control theory show that our approach is efficient. '
article_processing_charge: No
author:
- first_name: Hui
  full_name: Kong, Hui
  id: 3BDE25AA-F248-11E8-B48F-1D18A9856A87
  last_name: Kong
  orcid: 0000-0002-3066-6941
- first_name: Sergiy
  full_name: Bogomolov, Sergiy
  last_name: Bogomolov
  orcid: 0000-0002-0686-0365
- first_name: Christian
  full_name: Schilling, Christian
  last_name: Schilling
- first_name: Yu
  full_name: Jiang, Yu
  last_name: Jiang
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: 'Kong H, Bogomolov S, Schilling C, Jiang Y, Henzinger TA. Safety verification
    of nonlinear hybrid systems based on invariant clusters. In: <i>Proceedings of
    the 20th International Conference on Hybrid Systems</i>. ACM; 2017:163-172. doi:<a
    href="https://doi.org/10.1145/3049797.3049814">10.1145/3049797.3049814</a>'
  apa: 'Kong, H., Bogomolov, S., Schilling, C., Jiang, Y., &#38; Henzinger, T. A.
    (2017). Safety verification of nonlinear hybrid systems based on invariant clusters.
    In <i>Proceedings of the 20th International Conference on Hybrid Systems</i> (pp.
    163–172). Pittsburgh, PA, United States: ACM. <a href="https://doi.org/10.1145/3049797.3049814">https://doi.org/10.1145/3049797.3049814</a>'
  chicago: Kong, Hui, Sergiy Bogomolov, Christian Schilling, Yu Jiang, and Thomas
    A Henzinger. “Safety Verification of Nonlinear Hybrid Systems Based on Invariant
    Clusters.” In <i>Proceedings of the 20th International Conference on Hybrid Systems</i>,
    163–72. ACM, 2017. <a href="https://doi.org/10.1145/3049797.3049814">https://doi.org/10.1145/3049797.3049814</a>.
  ieee: H. Kong, S. Bogomolov, C. Schilling, Y. Jiang, and T. A. Henzinger, “Safety
    verification of nonlinear hybrid systems based on invariant clusters,” in <i>Proceedings
    of the 20th International Conference on Hybrid Systems</i>, Pittsburgh, PA, United
    States, 2017, pp. 163–172.
  ista: 'Kong H, Bogomolov S, Schilling C, Jiang Y, Henzinger TA. 2017. Safety verification
    of nonlinear hybrid systems based on invariant clusters. Proceedings of the 20th
    International Conference on Hybrid Systems. HSCC: Hybrid Systems - Computation
    and Control , 163–172.'
  mla: Kong, Hui, et al. “Safety Verification of Nonlinear Hybrid Systems Based on
    Invariant Clusters.” <i>Proceedings of the 20th International Conference on Hybrid
    Systems</i>, ACM, 2017, pp. 163–72, doi:<a href="https://doi.org/10.1145/3049797.3049814">10.1145/3049797.3049814</a>.
  short: H. Kong, S. Bogomolov, C. Schilling, Y. Jiang, T.A. Henzinger, in:, Proceedings
    of the 20th International Conference on Hybrid Systems, ACM, 2017, pp. 163–172.
conference:
  end_date: 2017-04-20
  location: Pittsburgh, PA, United States
  name: 'HSCC: Hybrid Systems - Computation and Control '
  start_date: 2017-04-18
date_created: 2018-12-11T11:47:47Z
date_published: 2017-04-01T00:00:00Z
date_updated: 2025-09-11T07:06:15Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1145/3049797.3049814
external_id:
  isi:
  - '000615962400019'
file:
- access_level: open_access
  checksum: b7667434cbf5b5f0ade3bea1dbe5bf63
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:20Z
  date_updated: 2020-07-14T12:47:34Z
  file_id: '4873'
  file_name: IST-2017-817-v1+1_p163-kong.pdf
  file_size: 1650530
  relation: main_file
file_date_updated: 2020-07-14T12:47:34Z
fulldoi: https://doi.org/10.1145/3049797.3049814
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 163 - 172
publication: Proceedings of the 20th International Conference on Hybrid Systems
publication_identifier:
  isbn:
  - 978-145034590-3
publication_status: published
publisher: ACM
publist_id: '7067'
pubrep_id: '817'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Safety verification of nonlinear hybrid systems based on invariant clusters
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2017'
...
---
_id: '666'
abstract:
- lang: eng
  text: Antibiotics elicit drastic changes in microbial gene expression, including
    the induction of stress response genes. While certain stress responses are known
    to “cross-protect” bacteria from other stressors, it is unclear whether cellular
    responses to antibiotics have a similar protective role. By measuring the genome-wide
    transcriptional response dynamics of Escherichia coli to four antibiotics, we
    found that trimethoprim induces a rapid acid stress response that protects bacteria
    from subsequent exposure to acid. Combining microfluidics with time-lapse imaging
    to monitor survival and acid stress response in single cells revealed that the
    noisy expression of the acid resistance operon gadBC correlates with single-cell
    survival. Cells with higher gadBC expression following trimethoprim maintain higher
    intracellular pH and survive the acid stress longer. The seemingly random single-cell
    survival under acid stress can therefore be predicted from gadBC expression and
    rationalized in terms of GadB/C molecular function. Overall, we provide a roadmap
    for identifying the molecular mechanisms of single-cell cross-protection between
    antibiotics and other stressors.
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Karin
  full_name: Mitosch, Karin
  id: 39B66846-F248-11E8-B48F-1D18A9856A87
  last_name: Mitosch
- first_name: Georg
  full_name: Rieckh, Georg
  id: 34DA8BD6-F248-11E8-B48F-1D18A9856A87
  last_name: Rieckh
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Mitosch K, Rieckh G, Bollenbach MT. Noisy response to antibiotic stress predicts
    subsequent single cell survival in an acidic environment. <i>Cell Systems</i>.
    2017;4(4):393-403. doi:<a href="https://doi.org/10.1016/j.cels.2017.03.001">10.1016/j.cels.2017.03.001</a>
  apa: Mitosch, K., Rieckh, G., &#38; Bollenbach, M. T. (2017). Noisy response to
    antibiotic stress predicts subsequent single cell survival in an acidic environment.
    <i>Cell Systems</i>. Cell Press. <a href="https://doi.org/10.1016/j.cels.2017.03.001">https://doi.org/10.1016/j.cels.2017.03.001</a>
  chicago: Mitosch, Karin, Georg Rieckh, and Mark Tobias Bollenbach. “Noisy Response
    to Antibiotic Stress Predicts Subsequent Single Cell Survival in an Acidic Environment.”
    <i>Cell Systems</i>. Cell Press, 2017. <a href="https://doi.org/10.1016/j.cels.2017.03.001">https://doi.org/10.1016/j.cels.2017.03.001</a>.
  ieee: K. Mitosch, G. Rieckh, and M. T. Bollenbach, “Noisy response to antibiotic
    stress predicts subsequent single cell survival in an acidic environment,” <i>Cell
    Systems</i>, vol. 4, no. 4. Cell Press, pp. 393–403, 2017.
  ista: Mitosch K, Rieckh G, Bollenbach MT. 2017. Noisy response to antibiotic stress
    predicts subsequent single cell survival in an acidic environment. Cell Systems.
    4(4), 393–403.
  mla: Mitosch, Karin, et al. “Noisy Response to Antibiotic Stress Predicts Subsequent
    Single Cell Survival in an Acidic Environment.” <i>Cell Systems</i>, vol. 4, no.
    4, Cell Press, 2017, pp. 393–403, doi:<a href="https://doi.org/10.1016/j.cels.2017.03.001">10.1016/j.cels.2017.03.001</a>.
  short: K. Mitosch, G. Rieckh, M.T. Bollenbach, Cell Systems 4 (2017) 393–403.
corr_author: '1'
date_created: 2018-12-11T11:47:48Z
date_published: 2017-04-26T00:00:00Z
date_updated: 2026-04-08T14:21:56Z
day: '26'
ddc:
- '576'
- '610'
department:
- _id: ToBo
- _id: GaTk
doi: 10.1016/j.cels.2017.03.001
ec_funded: 1
external_id:
  isi:
  - '000402747300005'
file:
- access_level: open_access
  checksum: 04ff20011c3d9a601c514aa999a5fe1a
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:54Z
  date_updated: 2020-07-14T12:47:35Z
  file_id: '5041'
  file_name: IST-2017-901-v1+1_1-s2.0-S2405471217300868-main.pdf
  file_size: 2438660
  relation: main_file
file_date_updated: 2020-07-14T12:47:35Z
fulldoi: https://doi.org/10.1016/j.cels.2017.03.001
has_accepted_license: '1'
intvolume: '         4'
isi: 1
issue: '4'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 393 - 403
project:
- _id: 25E83C2C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '303507'
  name: Optimality principles in responses to antibiotics
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27201-B22
  name: Revealing the mechanisms underlying drug interactions
- _id: 25EB3A80-B435-11E9-9278-68D0E5697425
  grant_number: RGP0042/2013
  name: Revealing the fundamental limits of cell growth
publication: Cell Systems
publication_identifier:
  issn:
  - 2405-4712
publication_status: published
publisher: Cell Press
publist_id: '7061'
pubrep_id: '901'
quality_controlled: '1'
related_material:
  record:
  - id: '818'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Noisy response to antibiotic stress predicts subsequent single cell survival
  in an acidic environment
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 4
year: '2017'
...
---
_id: '6679'
abstract:
- lang: eng
  text: 'Polar codes represent one of the major recent breakthroughs in coding theory
    and, because of their attractive features, they have been selected for the incoming
    5G standard. As such, a lot of attention has been devoted to the development of
    decoding algorithms with good error performance and efficient hardware implementation.
    One of the leading candidates in this regard is represented by successive-cancellation
    list (SCL) decoding. However, its hardware implementation requires a large amount
    of memory. Recently, a partitioned SCL (PSCL) decoder has been proposed to significantly
    reduce the memory consumption [1]. In this paper, we examine the paradigm of PSCL
    decoding from both theoretical and practical standpoints: (i) by changing the
    construction of the code, we are able to improve the performance at no additional
    computational, latency or memory cost, (ii) we present an optimal scheme to allocate
    cyclic redundancy checks (CRCs), and (iii) we provide an upper bound on the list
    size that allows MAP performance.'
arxiv: 1
author:
- first_name: Seyyed Ali
  full_name: Hashemi, Seyyed Ali
  last_name: Hashemi
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Hamed
  full_name: Hassani, Hamed
  last_name: Hassani
- first_name: Ruediger
  full_name: Urbanke, Ruediger
  last_name: Urbanke
- first_name: Warren
  full_name: Gross, Warren
  last_name: Gross
citation:
  ama: 'Hashemi SA, Mondelli M, Hassani H, Urbanke R, Gross W. Partitioned list decoding
    of polar codes: Analysis and improvement of finite length performance. In: <i>2017
    IEEE Global Communications Conference</i>. IEEE; 2017:1-7. doi:<a href="https://doi.org/10.1109/glocom.2017.8254940">10.1109/glocom.2017.8254940</a>'
  apa: 'Hashemi, S. A., Mondelli, M., Hassani, H., Urbanke, R., &#38; Gross, W. (2017).
    Partitioned list decoding of polar codes: Analysis and improvement of finite length
    performance. In <i>2017 IEEE Global Communications Conference</i> (pp. 1–7). Singapore,
    Singapore: IEEE. <a href="https://doi.org/10.1109/glocom.2017.8254940">https://doi.org/10.1109/glocom.2017.8254940</a>'
  chicago: 'Hashemi, Seyyed Ali, Marco Mondelli, Hamed Hassani, Ruediger Urbanke,
    and Warren Gross. “Partitioned List Decoding of Polar Codes: Analysis and Improvement
    of Finite Length Performance.” In <i>2017 IEEE Global Communications Conference</i>,
    1–7. IEEE, 2017. <a href="https://doi.org/10.1109/glocom.2017.8254940">https://doi.org/10.1109/glocom.2017.8254940</a>.'
  ieee: 'S. A. Hashemi, M. Mondelli, H. Hassani, R. Urbanke, and W. Gross, “Partitioned
    list decoding of polar codes: Analysis and improvement of finite length performance,”
    in <i>2017 IEEE Global Communications Conference</i>, Singapore, Singapore, 2017,
    pp. 1–7.'
  ista: 'Hashemi SA, Mondelli M, Hassani H, Urbanke R, Gross W. 2017. Partitioned
    list decoding of polar codes: Analysis and improvement of finite length performance.
    2017 IEEE Global Communications Conference. GLOBECOM: Global Communications Conference,
    1–7.'
  mla: 'Hashemi, Seyyed Ali, et al. “Partitioned List Decoding of Polar Codes: Analysis
    and Improvement of Finite Length Performance.” <i>2017 IEEE Global Communications
    Conference</i>, IEEE, 2017, pp. 1–7, doi:<a href="https://doi.org/10.1109/glocom.2017.8254940">10.1109/glocom.2017.8254940</a>.'
  short: S.A. Hashemi, M. Mondelli, H. Hassani, R. Urbanke, W. Gross, in:, 2017 IEEE
    Global Communications Conference, IEEE, 2017, pp. 1–7.
conference:
  end_date: 2017-12-08
  location: Singapore, Singapore
  name: 'GLOBECOM: Global Communications Conference'
  start_date: 2017-12-04
date_created: 2019-07-24T13:55:25Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:08:34Z
day: '01'
doi: 10.1109/glocom.2017.8254940
extern: '1'
external_id:
  arxiv:
  - '1705.05497'
fulldoi: https://doi.org/10.1109/glocom.2017.8254940
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1705.05497
month: '12'
oa: 1
oa_version: Preprint
page: 1-7
publication: 2017 IEEE Global Communications Conference
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: 'Partitioned list decoding of polar codes: Analysis and improvement of finite
  length performance'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '668'
abstract:
- lang: eng
  text: Macrophage filopodia, finger-like membrane protrusions, were first implicated
    in phagocytosis more than 100 years ago, but little is still known about the involvement
    of these actin-dependent structures in particle clearance. Using spinning disk
    confocal microscopy to image filopodial dynamics in mouse resident Lifeact-EGFP
    macrophages, we show that filopodia, or filopodia-like structures, support pathogen
    clearance by multiple means. Filopodia supported the phagocytic uptake of bacterial
    (Escherichia coli) particles by (i) capturing along the filopodial shaft and surfing
    toward the cell body, the most common mode of capture; (ii) capturing via the
    tip followed by retraction; (iii) combinations of surfing and retraction; or (iv)
    sweeping actions. In addition, filopodia supported the uptake of zymosan (Saccharomyces
    cerevisiae) particles by (i) providing fixation, (ii) capturing at the tip and
    filopodia-guided actin anterograde flow with phagocytic cup formation, and (iii)
    the rapid growth of new protrusions. To explore the role of filopodia-inducing
    Cdc42, we generated myeloid-restricted Cdc42 knock-out mice. Cdc42-deficient macrophages
    exhibited rapid phagocytic cup kinetics, but reduced particle clearance, which
    could be explained by the marked rounded-up morphology of these cells. Macrophages
    lacking Myo10, thought to act downstream of Cdc42, had normal morphology, motility,
    and phagocytic cup formation, but displayed markedly reduced filopodia formation.
    In conclusion, live-cell imaging revealed multiple mechanisms involving macrophage
    filopodia in particle capture and engulfment. Cdc42 is not critical for filopodia
    or phagocytic cup formation, but plays a key role in driving macrophage lamellipodial
    spreading.
article_processing_charge: No
article_type: original
author:
- first_name: Markus
  full_name: Horsthemke, Markus
  last_name: Horsthemke
- first_name: Anne
  full_name: Bachg, Anne
  last_name: Bachg
- first_name: Katharina
  full_name: Groll, Katharina
  last_name: Groll
- first_name: Sven
  full_name: Moyzio, Sven
  last_name: Moyzio
- first_name: Barbara
  full_name: Müther, Barbara
  last_name: Müther
- first_name: Sandra
  full_name: Hemkemeyer, Sandra
  last_name: Hemkemeyer
- first_name: Roland
  full_name: Wedlich Söldner, Roland
  last_name: Wedlich Söldner
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Sebastian
  full_name: Tacke, Sebastian
  last_name: Tacke
- first_name: Martin
  full_name: Bähler, Martin
  last_name: Bähler
- first_name: Peter
  full_name: Hanley, Peter
  last_name: Hanley
citation:
  ama: Horsthemke M, Bachg A, Groll K, et al. Multiple roles of filopodial dynamics
    in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion.
    <i>Journal of Biological Chemistry</i>. 2017;292(17):7258-7273. doi:<a href="https://doi.org/10.1074/jbc.M116.766923">10.1074/jbc.M116.766923</a>
  apa: Horsthemke, M., Bachg, A., Groll, K., Moyzio, S., Müther, B., Hemkemeyer, S.,
    … Hanley, P. (2017). Multiple roles of filopodial dynamics in particle capture
    and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. <i>Journal of Biological
    Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href="https://doi.org/10.1074/jbc.M116.766923">https://doi.org/10.1074/jbc.M116.766923</a>
  chicago: Horsthemke, Markus, Anne Bachg, Katharina Groll, Sven Moyzio, Barbara Müther,
    Sandra Hemkemeyer, Roland Wedlich Söldner, et al. “Multiple Roles of Filopodial
    Dynamics in Particle Capture and Phagocytosis and Phenotypes of Cdc42 and Myo10
    Deletion.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry
    and Molecular Biology, 2017. <a href="https://doi.org/10.1074/jbc.M116.766923">https://doi.org/10.1074/jbc.M116.766923</a>.
  ieee: M. Horsthemke <i>et al.</i>, “Multiple roles of filopodial dynamics in particle
    capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion,” <i>Journal
    of Biological Chemistry</i>, vol. 292, no. 17. American Society for Biochemistry
    and Molecular Biology, pp. 7258–7273, 2017.
  ista: Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, Wedlich
    Söldner R, Sixt MK, Tacke S, Bähler M, Hanley P. 2017. Multiple roles of filopodial
    dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10
    deletion. Journal of Biological Chemistry. 292(17), 7258–7273.
  mla: Horsthemke, Markus, et al. “Multiple Roles of Filopodial Dynamics in Particle
    Capture and Phagocytosis and Phenotypes of Cdc42 and Myo10 Deletion.” <i>Journal
    of Biological Chemistry</i>, vol. 292, no. 17, American Society for Biochemistry
    and Molecular Biology, 2017, pp. 7258–73, doi:<a href="https://doi.org/10.1074/jbc.M116.766923">10.1074/jbc.M116.766923</a>.
  short: M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R.
    Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological
    Chemistry 292 (2017) 7258–7273.
date_created: 2018-12-11T11:47:49Z
date_published: 2017-04-28T00:00:00Z
date_updated: 2025-09-11T07:03:17Z
day: '28'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1074/jbc.M116.766923
external_id:
  isi:
  - '000400478300035'
file:
- access_level: open_access
  checksum: d488162874326a4bb056065fa549dc4a
  content_type: application/pdf
  creator: dernst
  date_created: 2019-10-24T15:25:42Z
  date_updated: 2020-07-14T12:47:37Z
  file_id: '6971'
  file_name: 2017_JBC_Horsthemke.pdf
  file_size: 5647880
  relation: main_file
file_date_updated: 2020-07-14T12:47:37Z
fulldoi: https://doi.org/10.1074/jbc.M116.766923
has_accepted_license: '1'
intvolume: '       292'
isi: 1
issue: '17'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 7258 - 7273
publication: Journal of Biological Chemistry
publication_identifier:
  issn:
  - 0021-9258
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '7059'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multiple roles of filopodial dynamics in particle capture and phagocytosis
  and phenotypes of Cdc42 and Myo10 deletion
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 292
year: '2017'
...
---
_id: '669'
abstract:
- lang: eng
  text: 'The exocyst, a eukaryotic tethering complex, coregulates targeted exocytosis
    as an effector of small GTPases in polarized cell growth. In land plants, several
    exocyst subunits are encoded by double or triple paralogs, culminating in tens
    of EXO70 paralogs. Out of 23 Arabidopsis thaliana EXO70 isoforms, we analyzed
    seven isoforms expressed in pollen. Genetic and microscopic analyses of single
    mutants in EXO70A2, EXO70C1, EXO70C2, EXO70F1, EXO70H3, EXO70H5, and EXO70H6 genes
    revealed that only a loss-of-function EXO70C2 allele resulted in a significant
    male-specific transmission defect (segregation 40%:51%:9%) due to aberrant pollen
    tube growth. Mutant pollen tubes grown in vitro exhibited an enhanced growth rate
    and a decreased thickness of the tip cell wall, causing tip bursts. However, exo70C2
    pollen tubes could frequently recover and restart their speedy elongation, resulting
    in a repetitive stop-and-go growth dynamics. A pollenspecific depletion of the
    closest paralog, EXO70C1, using artificial microRNA in the exo70C2 mutant background,
    resulted in a complete pollen-specific transmission defect, suggesting redundant
    functions of EXO70C1 and EXO70C2. Both EXO70C1 and EXO70C2, GFP tagged and expressed
    under the control of their native promoters, localized in the cytoplasm of pollen
    grains, pollen tubes, and also root trichoblast cells. The expression of EXO70C2-GFP
    complemented the aberrant growth of exo70C2 pollen tubes. The absent EXO70C2 interactions
    with core exocyst subunits in the yeast two-hybrid assay, cytoplasmic localization,
    and genetic effect suggest an unconventional EXO70 function possibly as a regulator
    of exocytosis outside the exocyst complex. In conclusion, EXO70C2 is a novel factor
    contributing to the regulation of optimal tip growth of Arabidopsis pollen tubes. '
article_processing_charge: No
article_type: original
author:
- first_name: Lukáš
  full_name: Synek, Lukáš
  last_name: Synek
- first_name: Nemanja
  full_name: Vukašinović, Nemanja
  last_name: Vukašinović
- first_name: Ivan
  full_name: Kulich, Ivan
  last_name: Kulich
- first_name: Michal
  full_name: Hála, Michal
  last_name: Hála
- first_name: Klára
  full_name: Aldorfová, Klára
  last_name: Aldorfová
- first_name: Matyas
  full_name: Fendrych, Matyas
  id: 43905548-F248-11E8-B48F-1D18A9856A87
  last_name: Fendrych
  orcid: 0000-0002-9767-8699
- first_name: Viktor
  full_name: Žárský, Viktor
  last_name: Žárský
citation:
  ama: Synek L, Vukašinović N, Kulich I, et al. EXO70C2 is a key regulatory factor
    for optimal tip growth of pollen. <i>Plant Physiology</i>. 2017;174(1):223-240.
    doi:<a href="https://doi.org/10.1104/pp.16.01282">10.1104/pp.16.01282</a>
  apa: Synek, L., Vukašinović, N., Kulich, I., Hála, M., Aldorfová, K., Fendrych,
    M., &#38; Žárský, V. (2017). EXO70C2 is a key regulatory factor for optimal tip
    growth of pollen. <i>Plant Physiology</i>. American Society of Plant Biologists.
    <a href="https://doi.org/10.1104/pp.16.01282">https://doi.org/10.1104/pp.16.01282</a>
  chicago: Synek, Lukáš, Nemanja Vukašinović, Ivan Kulich, Michal Hála, Klára Aldorfová,
    Matyas Fendrych, and Viktor Žárský. “EXO70C2 Is a Key Regulatory Factor for Optimal
    Tip Growth of Pollen.” <i>Plant Physiology</i>. American Society of Plant Biologists,
    2017. <a href="https://doi.org/10.1104/pp.16.01282">https://doi.org/10.1104/pp.16.01282</a>.
  ieee: L. Synek <i>et al.</i>, “EXO70C2 is a key regulatory factor for optimal tip
    growth of pollen,” <i>Plant Physiology</i>, vol. 174, no. 1. American Society
    of Plant Biologists, pp. 223–240, 2017.
  ista: Synek L, Vukašinović N, Kulich I, Hála M, Aldorfová K, Fendrych M, Žárský
    V. 2017. EXO70C2 is a key regulatory factor for optimal tip growth of pollen.
    Plant Physiology. 174(1), 223–240.
  mla: Synek, Lukáš, et al. “EXO70C2 Is a Key Regulatory Factor for Optimal Tip Growth
    of Pollen.” <i>Plant Physiology</i>, vol. 174, no. 1, American Society of Plant
    Biologists, 2017, pp. 223–40, doi:<a href="https://doi.org/10.1104/pp.16.01282">10.1104/pp.16.01282</a>.
  short: L. Synek, N. Vukašinović, I. Kulich, M. Hála, K. Aldorfová, M. Fendrych,
    V. Žárský, Plant Physiology 174 (2017) 223–240.
date_created: 2018-12-11T11:47:49Z
date_published: 2017-05-01T00:00:00Z
date_updated: 2025-09-11T07:02:41Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1104/pp.16.01282
external_id:
  isi:
  - '000402057200017'
  pmid:
  - '28356503'
file:
- access_level: open_access
  checksum: 97155acc6aa5f0d0a78e0589a932fe02
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-18T16:16:18Z
  date_updated: 2020-07-14T12:47:37Z
  file_id: '7041'
  file_name: 2017_PlantPhysio_Synek.pdf
  file_size: 2176903
  relation: main_file
file_date_updated: 2020-07-14T12:47:37Z
fulldoi: https://doi.org/10.1104/pp.16.01282
has_accepted_license: '1'
intvolume: '       174'
isi: 1
issue: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 223 - 240
pmid: 1
publication: Plant Physiology
publication_identifier:
  issn:
  - 0032-0889
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '7058'
quality_controlled: '1'
scopus_import: '1'
status: public
title: EXO70C2 is a key regulatory factor for optimal tip growth of pollen
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 174
year: '2017'
...
---
_id: '670'
abstract:
- lang: eng
  text: We propose an efficient method to model paper tearing in the context of interactive
    modeling. The method uses geometrical information to automatically detect potential
    starting points of tears. We further introduce a new hybrid geometrical and physical-based
    method to compute the trajectory of tears while procedurally synthesizing high
    resolution details of the tearing path using a texture based approach. The results
    obtained are compared with real paper and with previous studies on the expected
    geometric paths of paper that tears.
article_processing_charge: No
article_type: original
author:
- first_name: Camille
  full_name: Schreck, Camille
  id: 2B14B676-F248-11E8-B48F-1D18A9856A87
  last_name: Schreck
- first_name: Damien
  full_name: Rohmer, Damien
  last_name: Rohmer
- first_name: Stefanie
  full_name: Hahmann, Stefanie
  last_name: Hahmann
citation:
  ama: Schreck C, Rohmer D, Hahmann S. Interactive paper tearing. <i>Computer Graphics
    Forum</i>. 2017;36(2):95-106. doi:<a href="https://doi.org/10.1111/cgf.13110">10.1111/cgf.13110</a>
  apa: Schreck, C., Rohmer, D., &#38; Hahmann, S. (2017). Interactive paper tearing.
    <i>Computer Graphics Forum</i>. Wiley. <a href="https://doi.org/10.1111/cgf.13110">https://doi.org/10.1111/cgf.13110</a>
  chicago: Schreck, Camille, Damien Rohmer, and Stefanie Hahmann. “Interactive Paper
    Tearing.” <i>Computer Graphics Forum</i>. Wiley, 2017. <a href="https://doi.org/10.1111/cgf.13110">https://doi.org/10.1111/cgf.13110</a>.
  ieee: C. Schreck, D. Rohmer, and S. Hahmann, “Interactive paper tearing,” <i>Computer
    Graphics Forum</i>, vol. 36, no. 2. Wiley, pp. 95–106, 2017.
  ista: Schreck C, Rohmer D, Hahmann S. 2017. Interactive paper tearing. Computer
    Graphics Forum. 36(2), 95–106.
  mla: Schreck, Camille, et al. “Interactive Paper Tearing.” <i>Computer Graphics
    Forum</i>, vol. 36, no. 2, Wiley, 2017, pp. 95–106, doi:<a href="https://doi.org/10.1111/cgf.13110">10.1111/cgf.13110</a>.
  short: C. Schreck, D. Rohmer, S. Hahmann, Computer Graphics Forum 36 (2017) 95–106.
date_created: 2018-12-11T11:47:49Z
date_published: 2017-05-01T00:00:00Z
date_updated: 2025-09-11T07:02:03Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1111/cgf.13110
external_id:
  isi:
  - '000404474000011'
fulldoi: https://doi.org/10.1111/cgf.13110
intvolume: '        36'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.inria.fr/hal-01647113/file/eg_2017_schreck_paper_tearing.pdf
month: '05'
oa: 1
oa_version: Published Version
page: 95 - 106
project:
- _id: 25357BD2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 24352-N23
  name: 'Deep Pictures: Creating Visual and Haptic Vector Images'
publication: Computer Graphics Forum
publication_identifier:
  issn:
  - '01677055'
publication_status: published
publisher: Wiley
publist_id: '7056'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interactive paper tearing
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 36
year: '2017'
...
---
_id: '671'
abstract:
- lang: eng
  text: Humans routinely use conditionally cooperative strategies when interacting
    in repeated social dilemmas. They are more likely to cooperate if others cooperated
    before, and are ready to retaliate if others defected. To capture the emergence
    of reciprocity, most previous models consider subjects who can only choose from
    a restricted set of representative strategies, or who react to the outcome of
    the very last round only. As players memorize more rounds, the dimension of the
    strategy space increases exponentially. This increasing computational complexity
    renders simulations for individuals with higher cognitive abilities infeasible,
    especially if multiplayer interactions are taken into account. Here, we take an
    axiomatic approach instead. We propose several properties that a robust cooperative
    strategy for a repeated multiplayer dilemma should have. These properties naturally
    lead to a unique class of cooperative strategies, which contains the classical
    Win-Stay Lose-Shift rule as a special case. A comprehensive numerical analysis
    for the prisoner's dilemma and for the public goods game suggests that strategies
    of this class readily evolve across various memory-n spaces. Our results reveal
    that successful strategies depend not only on how cooperative others were in the
    past but also on the respective context of cooperation.
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Vaquero
  full_name: Martinez, Vaquero
  last_name: Martinez
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Hilbe C, Martinez V, Chatterjee K, Nowak M. Memory-n strategies of direct reciprocity.
    <i>PNAS</i>. 2017;114(18):4715-4720. doi:<a href="https://doi.org/10.1073/pnas.1621239114">10.1073/pnas.1621239114</a>
  apa: Hilbe, C., Martinez, V., Chatterjee, K., &#38; Nowak, M. (2017). Memory-n strategies
    of direct reciprocity. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1621239114">https://doi.org/10.1073/pnas.1621239114</a>
  chicago: Hilbe, Christian, Vaquero Martinez, Krishnendu Chatterjee, and Martin Nowak.
    “Memory-n Strategies of Direct Reciprocity.” <i>PNAS</i>. National Academy of
    Sciences, 2017. <a href="https://doi.org/10.1073/pnas.1621239114">https://doi.org/10.1073/pnas.1621239114</a>.
  ieee: C. Hilbe, V. Martinez, K. Chatterjee, and M. Nowak, “Memory-n strategies of
    direct reciprocity,” <i>PNAS</i>, vol. 114, no. 18. National Academy of Sciences,
    pp. 4715–4720, 2017.
  ista: Hilbe C, Martinez V, Chatterjee K, Nowak M. 2017. Memory-n strategies of direct
    reciprocity. PNAS. 114(18), 4715–4720.
  mla: Hilbe, Christian, et al. “Memory-n Strategies of Direct Reciprocity.” <i>PNAS</i>,
    vol. 114, no. 18, National Academy of Sciences, 2017, pp. 4715–20, doi:<a href="https://doi.org/10.1073/pnas.1621239114">10.1073/pnas.1621239114</a>.
  short: C. Hilbe, V. Martinez, K. Chatterjee, M. Nowak, PNAS 114 (2017) 4715–4720.
corr_author: '1'
date_created: 2018-12-11T11:47:50Z
date_published: 2017-05-02T00:00:00Z
date_updated: 2026-06-18T19:11:14Z
day: '02'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1073/pnas.1621239114
ec_funded: 1
external_id:
  isi:
  - '000400358000050'
  pmid:
  - '28420786'
fulldoi: https://doi.org/10.1073/pnas.1621239114
intvolume: '       114'
isi: 1
issue: '18'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422766/
month: '05'
oa: 1
oa_version: Published Version
page: 4715 - 4720
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: PNAS
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '7053'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Memory-n strategies of direct reciprocity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '672'
abstract:
- lang: eng
  text: Trafficking cells frequently transmigrate through epithelial and endothelial
    monolayers. How monolayers cooperate with the penetrating cells to support their
    transit is poorly understood. We studied dendritic cell (DC) entry into lymphatic
    capillaries as a model system for transendothelial migration. We find that the
    chemokine CCL21, which is the decisive guidance cue for intravasation, mainly
    localizes in the trans-Golgi network and intracellular vesicles of lymphatic endothelial
    cells. Upon DC transmigration, these Golgi deposits disperse and CCL21 becomes
    extracellularly enriched at the sites of endothelial cell-cell junctions. When
    we reconstitute the transmigration process in vitro, we find that secretion of
    CCL21-positive vesicles is triggered by a DC contact-induced calcium signal, and
    selective calcium chelation in lymphatic endothelium attenuates transmigration.
    Altogether, our data demonstrate a chemokine-mediated feedback between DCs and
    lymphatic endothelium, which facilitates transendothelial migration.
article_processing_charge: Yes
author:
- first_name: Kari
  full_name: Vaahtomeri, Kari
  id: 368EE576-F248-11E8-B48F-1D18A9856A87
  last_name: Vaahtomeri
  orcid: 0000-0001-7829-3518
- first_name: Markus
  full_name: Brown, Markus
  id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
  last_name: Brown
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Ingrid
  full_name: De Vries, Ingrid
  id: 4C7D837E-F248-11E8-B48F-1D18A9856A87
  last_name: De Vries
- first_name: Alexander F
  full_name: Leithner, Alexander F
  id: 3B1B77E4-F248-11E8-B48F-1D18A9856A87
  last_name: Leithner
  orcid: 0000-0002-1073-744X
- first_name: Matthias
  full_name: Mehling, Matthias
  id: 3C23B994-F248-11E8-B48F-1D18A9856A87
  last_name: Mehling
  orcid: 0000-0001-8599-1226
- first_name: Walter
  full_name: Kaufmann, Walter
  id: 3F99E422-F248-11E8-B48F-1D18A9856A87
  last_name: Kaufmann
  orcid: 0000-0001-9735-5315
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Vaahtomeri K, Brown M, Hauschild R, et al. Locally triggered release of the
    chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia.
    <i>Cell Reports</i>. 2017;19(5):902-909. doi:<a href="https://doi.org/10.1016/j.celrep.2017.04.027">10.1016/j.celrep.2017.04.027</a>
  apa: Vaahtomeri, K., Brown, M., Hauschild, R., de Vries, I., Leithner, A. F., Mehling,
    M., … Sixt, M. K. (2017). Locally triggered release of the chemokine CCL21 promotes
    dendritic cell transmigration across lymphatic endothelia. <i>Cell Reports</i>.
    Cell Press. <a href="https://doi.org/10.1016/j.celrep.2017.04.027">https://doi.org/10.1016/j.celrep.2017.04.027</a>
  chicago: Vaahtomeri, Kari, Markus Brown, Robert Hauschild, Ingrid de Vries, Alexander
    F Leithner, Matthias Mehling, Walter Kaufmann, and Michael K Sixt. “Locally Triggered
    Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic
    Endothelia.” <i>Cell Reports</i>. Cell Press, 2017. <a href="https://doi.org/10.1016/j.celrep.2017.04.027">https://doi.org/10.1016/j.celrep.2017.04.027</a>.
  ieee: K. Vaahtomeri <i>et al.</i>, “Locally triggered release of the chemokine CCL21
    promotes dendritic cell transmigration across lymphatic endothelia,” <i>Cell Reports</i>,
    vol. 19, no. 5. Cell Press, pp. 902–909, 2017.
  ista: Vaahtomeri K, Brown M, Hauschild R, de Vries I, Leithner AF, Mehling M, Kaufmann
    W, Sixt MK. 2017. Locally triggered release of the chemokine CCL21 promotes dendritic
    cell transmigration across lymphatic endothelia. Cell Reports. 19(5), 902–909.
  mla: Vaahtomeri, Kari, et al. “Locally Triggered Release of the Chemokine CCL21
    Promotes Dendritic Cell Transmigration across Lymphatic Endothelia.” <i>Cell Reports</i>,
    vol. 19, no. 5, Cell Press, 2017, pp. 902–09, doi:<a href="https://doi.org/10.1016/j.celrep.2017.04.027">10.1016/j.celrep.2017.04.027</a>.
  short: K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling,
    W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
corr_author: '1'
date_created: 2018-12-11T11:47:50Z
date_published: 2017-05-02T00:00:00Z
date_updated: 2025-09-10T14:27:34Z
day: '02'
ddc:
- '570'
department:
- _id: MiSi
- _id: Bio
- _id: EM-Fac
doi: 10.1016/j.celrep.2017.04.027
ec_funded: 1
external_id:
  isi:
  - '000402124100002'
file:
- access_level: open_access
  checksum: 8fdddaab1f1d76a6ec9ca94dcb6b07a2
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:54Z
  date_updated: 2020-07-14T12:47:38Z
  file_id: '5109'
  file_name: IST-2017-900-v1+1_1-s2.0-S2211124717305211-main.pdf
  file_size: 2248814
  relation: main_file
file_date_updated: 2020-07-14T12:47:38Z
fulldoi: https://doi.org/10.1016/j.celrep.2017.04.027
has_accepted_license: '1'
intvolume: '        19'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 902 - 909
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281556'
  name: Cytoskeletal force generation and force transduction of migrating leukocytes
- _id: 25A8E5EA-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Y 564-B12
  name: Cytoskeletal force generation and force transduction of migrating leukocytes
publication: Cell Reports
publication_identifier:
  issn:
  - 2211-1247
publication_status: published
publisher: Cell Press
publist_id: '7052'
pubrep_id: '900'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration
  across lymphatic endothelia
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 19
year: '2017'
...
---
_id: '6729'
abstract:
- lang: eng
  text: Consider the problem of constructing a polar code of block length N for the
    transmission over a given channel W. Typically this requires to compute the reliability
    of all the N synthetic channels and then to include those that are sufficiently
    reliable. However, we know from [1], [2] that there is a partial order among the
    synthetic channels. Hence, it is natural to ask whether we can exploit it to reduce
    the computational burden of the construction problem. We show that, if we take
    advantage of the partial order [1], [2], we can construct a polar code by computing
    the reliability of roughly N/ log 3/2 N synthetic channels. Such a set of synthetic
    channels is universal, in the sense that it allows one to construct polar codes
    for any W, and it can be identified by solving a maximum matching problem on a
    bipartite graph. Our proof technique consists in reducing the construction problem
    to the problem of computing the maximum cardinality of an antichain for a suitable
    partially ordered set. As such, this method is general and it can be used to further
    improve the complexity of the construction problem in case a new partial order
    on the synthetic channels of polar codes is discovered.
arxiv: 1
author:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: S. Hamed
  full_name: Hassani, S. Hamed
  last_name: Hassani
- first_name: Rudiger
  full_name: Urbanke, Rudiger
  last_name: Urbanke
citation:
  ama: 'Mondelli M, Hassani SH, Urbanke R. Construction of polar codes with sublinear
    complexity. In: <i>2017 IEEE International Symposium on Information Theory </i>.
    IEEE; 2017:1853-1857. doi:<a href="https://doi.org/10.1109/isit.2017.8006850">10.1109/isit.2017.8006850</a>'
  apa: 'Mondelli, M., Hassani, S. H., &#38; Urbanke, R. (2017). Construction of polar
    codes with sublinear complexity. In <i>2017 IEEE International Symposium on Information
    Theory </i> (pp. 1853–1857). Aachen, Germany: IEEE. <a href="https://doi.org/10.1109/isit.2017.8006850">https://doi.org/10.1109/isit.2017.8006850</a>'
  chicago: Mondelli, Marco, S. Hamed Hassani, and Rudiger Urbanke. “Construction of
    Polar Codes with Sublinear Complexity.” In <i>2017 IEEE International Symposium
    on Information Theory </i>, 1853–57. IEEE, 2017. <a href="https://doi.org/10.1109/isit.2017.8006850">https://doi.org/10.1109/isit.2017.8006850</a>.
  ieee: M. Mondelli, S. H. Hassani, and R. Urbanke, “Construction of polar codes with
    sublinear complexity,” in <i>2017 IEEE International Symposium on Information
    Theory </i>, Aachen, Germany, 2017, pp. 1853–1857.
  ista: 'Mondelli M, Hassani SH, Urbanke R. 2017. Construction of polar codes with
    sublinear complexity. 2017 IEEE International Symposium on Information Theory
    . ISIT: International Symposium on Information Theory, 1853–1857.'
  mla: Mondelli, Marco, et al. “Construction of Polar Codes with Sublinear Complexity.”
    <i>2017 IEEE International Symposium on Information Theory </i>, IEEE, 2017, pp.
    1853–57, doi:<a href="https://doi.org/10.1109/isit.2017.8006850">10.1109/isit.2017.8006850</a>.
  short: M. Mondelli, S.H. Hassani, R. Urbanke, in:, 2017 IEEE International Symposium
    on Information Theory , IEEE, 2017, pp. 1853–1857.
conference:
  end_date: 2017-06-30
  location: Aachen, Germany
  name: 'ISIT: International Symposium on Information Theory'
  start_date: 2017-06-25
date_created: 2019-07-30T07:14:18Z
date_published: 2017-06-15T00:00:00Z
date_updated: 2023-02-23T12:49:08Z
day: '15'
doi: 10.1109/isit.2017.8006850
extern: '1'
external_id:
  arxiv:
  - '1612.05295'
fulldoi: https://doi.org/10.1109/isit.2017.8006850
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1612.05295
month: '06'
oa: 1
oa_version: Preprint
page: 1853-1857
publication: '2017 IEEE International Symposium on Information Theory '
publication_identifier:
  eissn:
  - 2157-8117
  isbn:
  - '9781509040964'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '6663'
    relation: later_version
    status: public
status: public
title: Construction of polar codes with sublinear complexity
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '6730'
abstract:
- lang: eng
  text: We introduce a new approach to proving that a sequence of deterministic linear
    codes achieves capacity on an erasure channel under maximum a posteriori decoding.
    Rather than relying on the precise structure of the codes, our method exploits
    code symmetry. In particular, the technique applies to any sequence of linear
    codes where the blocklengths are strictly increasing, the code rates converge,
    and the permutation group of each code is doubly transitive. In other words, we
    show that symmetry alone implies near-optimal performance. An important consequence
    of this result is that a sequence of Reed-Muller codes with increasing block length
    and converging rate achieves capacity. This possibility has been suggested previously
    in the literature but it has only been proven for cases where the limiting code
    rate is 0 or 1. Moreover, these results extend naturally to all affine-invariant
    codes and, thus, to extended primitive narrow-sense BCH codes. This also resolves,
    in the affirmative, the existence question for capacity-achieving sequences of
    binary cyclic codes. The primary tools used in the proof are the sharp threshold
    property for symmetric monotone Boolean functions and the area theorem for extrinsic
    information transfer functions.
arxiv: 1
author:
- first_name: Shrinivas
  full_name: Kudekar, Shrinivas
  last_name: Kudekar
- first_name: Santhosh
  full_name: Kumar, Santhosh
  last_name: Kumar
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Henry D.
  full_name: Pfister, Henry D.
  last_name: Pfister
- first_name: Eren
  full_name: Sasoglu, Eren
  last_name: Sasoglu
- first_name: Ridiger L.
  full_name: Urbanke, Ridiger L.
  last_name: Urbanke
citation:
  ama: Kudekar S, Kumar S, Mondelli M, Pfister HD, Sasoglu E, Urbanke RL. Reed–Muller
    codes achieve capacity on erasure channels. <i>IEEE Transactions on Information
    Theory</i>. 2017;63(7):4298-4316. doi:<a href="https://doi.org/10.1109/tit.2017.2673829">10.1109/tit.2017.2673829</a>
  apa: Kudekar, S., Kumar, S., Mondelli, M., Pfister, H. D., Sasoglu, E., &#38; Urbanke,
    R. L. (2017). Reed–Muller codes achieve capacity on erasure channels. <i>IEEE
    Transactions on Information Theory</i>. IEEE. <a href="https://doi.org/10.1109/tit.2017.2673829">https://doi.org/10.1109/tit.2017.2673829</a>
  chicago: Kudekar, Shrinivas, Santhosh Kumar, Marco Mondelli, Henry D. Pfister, Eren
    Sasoglu, and Ridiger L. Urbanke. “Reed–Muller Codes Achieve Capacity on Erasure
    Channels.” <i>IEEE Transactions on Information Theory</i>. IEEE, 2017. <a href="https://doi.org/10.1109/tit.2017.2673829">https://doi.org/10.1109/tit.2017.2673829</a>.
  ieee: S. Kudekar, S. Kumar, M. Mondelli, H. D. Pfister, E. Sasoglu, and R. L. Urbanke,
    “Reed–Muller codes achieve capacity on erasure channels,” <i>IEEE Transactions
    on Information Theory</i>, vol. 63, no. 7. IEEE, pp. 4298–4316, 2017.
  ista: Kudekar S, Kumar S, Mondelli M, Pfister HD, Sasoglu E, Urbanke RL. 2017. Reed–Muller
    codes achieve capacity on erasure channels. IEEE Transactions on Information Theory.
    63(7), 4298–4316.
  mla: Kudekar, Shrinivas, et al. “Reed–Muller Codes Achieve Capacity on Erasure Channels.”
    <i>IEEE Transactions on Information Theory</i>, vol. 63, no. 7, IEEE, 2017, pp.
    4298–316, doi:<a href="https://doi.org/10.1109/tit.2017.2673829">10.1109/tit.2017.2673829</a>.
  short: S. Kudekar, S. Kumar, M. Mondelli, H.D. Pfister, E. Sasoglu, R.L. Urbanke,
    IEEE Transactions on Information Theory 63 (2017) 4298–4316.
date_created: 2019-07-30T07:18:11Z
date_published: 2017-07-01T00:00:00Z
date_updated: 2021-01-12T08:08:43Z
day: '01'
doi: 10.1109/tit.2017.2673829
extern: '1'
external_id:
  arxiv:
  - '1601.04689'
fulldoi: https://doi.org/10.1109/tit.2017.2673829
intvolume: '        63'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1601.04689
month: '07'
oa: 1
oa_version: Preprint
page: 4298-4316
publication: IEEE Transactions on Information Theory
publication_identifier:
  eissn:
  - 1557-9654
  issn:
  - 0018-9448
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: Reed–Muller codes achieve capacity on erasure channels
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 63
year: '2017'
...
---
_id: '6731'
abstract:
- lang: eng
  text: 'We present a rate-compatible polar coding scheme that achieves the capacity
    of any family of channels. Our solution generalizes the previous results [1],
    [2] that provide capacity-achieving rate-compatible polar codes for a degraded
    family of channels. The motivation for our extension comes from the fact that
    in many practical scenarios, e.g., MIMO systems and non-Gaussian interference,
    the channels cannot be ordered by degradation. The main technical contribution
    of this paper consists in removing the degradation condition. To do so, we exploit
    the ideas coming from the construction of universal polar codes. Our scheme possesses
    the usual attractive features of polar codes: low complexity code construction,
    encoding, and decoding; super-polynomial scaling of the error probability with
    the block length; and absence of error floors. On the negative side, the scaling
    of the gap to capacity with the block length is slower than in standard polar
    codes, and we prove an upper bound on the scaling exponent.'
article_number: '7919107'
arxiv: 1
author:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Hamed
  full_name: Hassani, Hamed
  last_name: Hassani
- first_name: Ivana
  full_name: Maric, Ivana
  last_name: Maric
- first_name: Dennis
  full_name: Hui, Dennis
  last_name: Hui
- first_name: Song-Nam
  full_name: Hong, Song-Nam
  last_name: Hong
citation:
  ama: 'Mondelli M, Hassani H, Maric I, Hui D, Hong S-N. Capacity-achieving rate-compatible
    polar codes for general channels. In: <i>2017 IEEE Wireless Communications and
    Networking Conference Workshops </i>. IEEE; 2017. doi:<a href="https://doi.org/10.1109/wcncw.2017.7919107">10.1109/wcncw.2017.7919107</a>'
  apa: 'Mondelli, M., Hassani, H., Maric, I., Hui, D., &#38; Hong, S.-N. (2017). Capacity-achieving
    rate-compatible polar codes for general channels. In <i>2017 IEEE Wireless Communications
    and Networking Conference Workshops </i>. San Francisco, CA, USA: IEEE. <a href="https://doi.org/10.1109/wcncw.2017.7919107">https://doi.org/10.1109/wcncw.2017.7919107</a>'
  chicago: Mondelli, Marco, Hamed Hassani, Ivana Maric, Dennis Hui, and Song-Nam Hong.
    “Capacity-Achieving Rate-Compatible Polar Codes for General Channels.” In <i>2017
    IEEE Wireless Communications and Networking Conference Workshops </i>. IEEE, 2017.
    <a href="https://doi.org/10.1109/wcncw.2017.7919107">https://doi.org/10.1109/wcncw.2017.7919107</a>.
  ieee: M. Mondelli, H. Hassani, I. Maric, D. Hui, and S.-N. Hong, “Capacity-achieving
    rate-compatible polar codes for general channels,” in <i>2017 IEEE Wireless Communications
    and Networking Conference Workshops </i>, San Francisco, CA, USA, 2017.
  ista: 'Mondelli M, Hassani H, Maric I, Hui D, Hong S-N. 2017. Capacity-achieving
    rate-compatible polar codes for general channels. 2017 IEEE Wireless Communications
    and Networking Conference Workshops . WCNCW: Wireless communications and networking
    conference workshops, 7919107.'
  mla: Mondelli, Marco, et al. “Capacity-Achieving Rate-Compatible Polar Codes for
    General Channels.” <i>2017 IEEE Wireless Communications and Networking Conference
    Workshops </i>, 7919107, IEEE, 2017, doi:<a href="https://doi.org/10.1109/wcncw.2017.7919107">10.1109/wcncw.2017.7919107</a>.
  short: M. Mondelli, H. Hassani, I. Maric, D. Hui, S.-N. Hong, in:, 2017 IEEE Wireless
    Communications and Networking Conference Workshops , IEEE, 2017.
conference:
  end_date: 2017-03-22
  location: San Francisco, CA, USA
  name: 'WCNCW: Wireless communications and networking conference workshops'
  start_date: 2017-03-19
date_created: 2019-07-31T05:56:58Z
date_published: 2017-05-04T00:00:00Z
date_updated: 2021-01-12T08:08:43Z
day: '04'
doi: 10.1109/wcncw.2017.7919107
extern: '1'
external_id:
  arxiv:
  - '1611.01199'
fulldoi: https://doi.org/10.1109/wcncw.2017.7919107
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1611.01199
month: '05'
oa: 1
oa_version: Preprint
publication: '2017 IEEE Wireless Communications and Networking Conference Workshops '
publication_identifier:
  isbn:
  - '9781509059089'
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: Capacity-achieving rate-compatible polar codes for general channels
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
