---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '19282'
abstract:
- lang: eng
  text: Osmium complexes with osmium in different oxidation states (II, III, IV, and
    VI) have been reported to exhibit antiproliferative activity in cancer cell lines.
    Herein, we demonstrate unexplored opportunities offered by 187Os nuclear forward
    scattering (NFS) and nuclear inelastic scattering (NIS) of synchrotron radiation
    for characterization of hyperfine interactions and lattice dynamics in a benchmark
    Os(VI) complex, K2[OsO2(OH)4]. We determined the isomer shift [δ = 3.3(1) millimeters
    per second] relative to [OsIVCl6]2− and quadrupole splitting [ΔEQ = 12.0(2) millimeters
    per second] with NFS. We estimated the Lamb-Mössbauer factor [0.80(4)], extracted
    the density of phonon states, and carried out a thermodynamics characterization
    using the NIS data combined with first-principles calculations. Overall, we provide
    evidence that 187Os nuclear resonance scattering is a reliable technique for the
    investigation of hyperfine interactions and Os-specific vibrations in osmium(VI)
    species and is thus applicable for such measurements in osmium complexes of other
    oxidation states, including those with anticancer activity such as Os(III) and
    Os(IV).
acknowledgement: "The European Synchrotron Radiation Facility is acknowledged for
  providing synchrotron radiation beamtime at the Nuclear Resonance beamlines ID18
  and ID14. The technical assistance of J.-P. Celse is acknowledged during the beamtime
  at the ESRF. V.B.A. and G.E.B. are thankful to Karl Mayer Stiftung (Triesen, Liechtenstein)
  and Valüna Stiftung (Vaduz, Liechtenstein) for financial support in purchasing the
  187Os metal. We are also thankful to A. Dobrov for help in the synthesis of 187OsO4
  from 187Os. Ab initio calculations were done on the ASPIRE-2A cluster (www.nscc.sg)
  under computational projects 11001278, 11003762, 51000267, and 11003763. This work
  used computational resources of the supercomputer Fugaku provided by RIKEN/NSCC
  through the HPCI System Research Project (project ID: hp240202). The computational
  resources of the HPC-NUS are gratefully acknowledged.\r\nThis work was supported
  by the Austrian Science Fund (FWF) grant I4729 (V.B.A.), King Saud University Researchers
  Supporting Project no. RSP2025R266 (L.F.C. and A.A.A.-K.), and National University
  of Singapore research projects A-8000709-00-00, A-8000017-00-00, and A-8001894-00-00
  (Z.H. and L.U.)."
article_number: eads3406
article_processing_charge: Yes
article_type: original
author:
- first_name: Iryna
  full_name: Stepanenko, Iryna
  id: 2a1f3914-89ea-11ee-b4f9-b6c903344e34
  last_name: Stepanenko
- first_name: Zhishuo
  full_name: Huang, Zhishuo
  last_name: Huang
- first_name: Liviu
  full_name: Ungur, Liviu
  last_name: Ungur
- first_name: Dimitrios
  full_name: Bessas, Dimitrios
  last_name: Bessas
- first_name: Aleksandr
  full_name: Chumakov, Aleksandr
  last_name: Chumakov
- first_name: Ilya
  full_name: Sergueev, Ilya
  last_name: Sergueev
- first_name: Gabriel E.
  full_name: Büchel, Gabriel E.
  last_name: Büchel
- first_name: Abdullah A.
  full_name: Al-Kahtani, Abdullah A.
  last_name: Al-Kahtani
- first_name: Liviu F.
  full_name: Chibotaru, Liviu F.
  last_name: Chibotaru
- first_name: Joshua
  full_name: Telser, Joshua
  last_name: Telser
- first_name: Vladimir B.
  full_name: Arion, Vladimir B.
  last_name: Arion
citation:
  ama: Stepanenko I, Huang Z, Ungur L, et al. 187Os nuclear resonance scattering to
    explore hyperfine interactions and lattice dynamics for biological applications.
    <i>Science Advances</i>. 2025;11(6). doi:<a href="https://doi.org/10.1126/sciadv.ads3406">10.1126/sciadv.ads3406</a>
  apa: Stepanenko, I., Huang, Z., Ungur, L., Bessas, D., Chumakov, A., Sergueev, I.,
    … Arion, V. B. (2025). 187Os nuclear resonance scattering to explore hyperfine
    interactions and lattice dynamics for biological applications. <i>Science Advances</i>.
    AAAS. <a href="https://doi.org/10.1126/sciadv.ads3406">https://doi.org/10.1126/sciadv.ads3406</a>
  chicago: Stepanenko, Iryna, Zhishuo Huang, Liviu Ungur, Dimitrios Bessas, Aleksandr
    Chumakov, Ilya Sergueev, Gabriel E. Büchel, et al. “187Os Nuclear Resonance Scattering
    to Explore Hyperfine Interactions and Lattice Dynamics for Biological Applications.”
    <i>Science Advances</i>. AAAS, 2025. <a href="https://doi.org/10.1126/sciadv.ads3406">https://doi.org/10.1126/sciadv.ads3406</a>.
  ieee: I. Stepanenko <i>et al.</i>, “187Os nuclear resonance scattering to explore
    hyperfine interactions and lattice dynamics for biological applications,” <i>Science
    Advances</i>, vol. 11, no. 6. AAAS, 2025.
  ista: Stepanenko I, Huang Z, Ungur L, Bessas D, Chumakov A, Sergueev I, Büchel GE,
    Al-Kahtani AA, Chibotaru LF, Telser J, Arion VB. 2025. 187Os nuclear resonance
    scattering to explore hyperfine interactions and lattice dynamics for biological
    applications. Science Advances. 11(6), eads3406.
  mla: Stepanenko, Iryna, et al. “187Os Nuclear Resonance Scattering to Explore Hyperfine
    Interactions and Lattice Dynamics for Biological Applications.” <i>Science Advances</i>,
    vol. 11, no. 6, eads3406, AAAS, 2025, doi:<a href="https://doi.org/10.1126/sciadv.ads3406">10.1126/sciadv.ads3406</a>.
  short: I. Stepanenko, Z. Huang, L. Ungur, D. Bessas, A. Chumakov, I. Sergueev, G.E.
    Büchel, A.A. Al-Kahtani, L.F. Chibotaru, J. Telser, V.B. Arion, Science Advances
    11 (2025).
date_created: 2025-03-02T23:01:53Z
date_published: 2025-02-07T00:00:00Z
date_updated: 2026-02-23T08:05:58Z
day: '07'
ddc:
- '530'
department:
- _id: StFr
doi: 10.1126/sciadv.ads3406
external_id:
  isi:
  - '001416079000003'
  pmid:
  - '39919179'
file:
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  date_updated: 2025-03-04T09:52:02Z
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file_date_updated: 2025-03-04T09:52:02Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: '6'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: 187Os nuclear resonance scattering to explore hyperfine interactions and lattice
  dynamics for biological applications
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2025'
...