---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20102'
abstract:
- lang: eng
text: 'Speciation is rarely observable directly. A way forward is to compare pairs
of ecotypes that evolved in parallel in similar contexts but have reached different
degrees of reproductive isolation. Such comparisons are possible in the marine
snail Littorina saxatilis by contrasting barriers to gene flow between parallel
ecotypes in Spain and Sweden. In both countries, divergent ecotypes have evolved
to withstand either crab predation or wave action. Here, we explore transects
spanning contact zones between the Crab and the Wave ecotypes using low-coverage
whole-genome sequencing, morphological and behavioural traits. Despite parallel
phenotypic divergence, distinct patterns of differentiation between the ecotypes
emerged: a continuous cline in Sweden indicating a weak barrier to gene flow,
but two highly genetically and phenotypically divergent, and partly spatially
overlapping clusters in Spain suggesting a much stronger barrier to gene flow.
The absence of Spanish early-generation hybrids supported strong isolation, but
a low level of gene flow is evident from molecular data. In both countries, highly
differentiated loci were located in both shared and country-specific chromosomal
inversions but were also present in collinear regions. Despite being considered
the same species and showing similar levels of phenotypic divergence, the Spanish
ecotypes are much closer to full reproductive isolation than the Swedish ones.
Barriers to gene flow of very different strengths between ecotypes within the
same species might be explained by dissimilarities in the spatial arrangement
of habitats, the selection gradients or the ages of the systems.'
acknowledgement: 'This study was supported by European Research Council grant 693030-BARRIERS
to RKB; the Swedish Research Council (grant number 2021-04191) to KJ; the Portuguese
Foundation for Science and Technology (FCT: 2020.00275.CEECIND and PTDC/BIA-EVL/1614/2021)
to RF; grant PID2022-137935NB-I00 by MICIU/AEI/ 10.13039/501100011033/and ERDF/EU
(ED431C 2020-05) to JG, grant PID2021-124930NB-I00 funded by MICIU/AEI/ 10.13039/501100011033/and
ERDF/EU to ERA, Xunta de Galicia (ED431C 2024/22), Centro singular de Investigación
de Galicia accreditation 2024-2027 (ED431G 2023/07), ‘ERDF A way of making Europe’
and Norwegian Research Council RCN, project 315287 to AMW.'
article_number: e70025
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Francesca
full_name: Raffini, Francesca
last_name: Raffini
- first_name: Aurélien
full_name: De Jode, Aurélien
last_name: De Jode
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Zuzanna B.
full_name: Zagrodzka, Zuzanna B.
last_name: Zagrodzka
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Juan
full_name: Galindo, Juan
last_name: Galindo
- first_name: Emilio
full_name: Rolán-Alvarez, Emilio
last_name: Rolán-Alvarez
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: Raffini F, De Jode A, Johannesson K, et al. Phenotypic divergence and genomic
architecture between parallel ecotypes at two different points on the speciation
continuum in a marine snail. Molecular Ecology. 2025;34(21). doi:10.1111/mec.70025
apa: Raffini, F., De Jode, A., Johannesson, K., Faria, R., Zagrodzka, Z. B., Westram,
A. M., … Butlin, R. K. (2025). Phenotypic divergence and genomic architecture
between parallel ecotypes at two different points on the speciation continuum
in a marine snail. Molecular Ecology. Wiley. https://doi.org/10.1111/mec.70025
chicago: Raffini, Francesca, Aurélien De Jode, Kerstin Johannesson, Rui Faria, Zuzanna
B. Zagrodzka, Anja M Westram, Juan Galindo, Emilio Rolán-Alvarez, and Roger K.
Butlin. “Phenotypic Divergence and Genomic Architecture between Parallel Ecotypes
at Two Different Points on the Speciation Continuum in a Marine Snail.” Molecular
Ecology. Wiley, 2025. https://doi.org/10.1111/mec.70025.
ieee: F. Raffini et al., “Phenotypic divergence and genomic architecture
between parallel ecotypes at two different points on the speciation continuum
in a marine snail,” Molecular Ecology, vol. 34, no. 21. Wiley, 2025.
ista: Raffini F, De Jode A, Johannesson K, Faria R, Zagrodzka ZB, Westram AM, Galindo
J, Rolán-Alvarez E, Butlin RK. 2025. Phenotypic divergence and genomic architecture
between parallel ecotypes at two different points on the speciation continuum
in a marine snail. Molecular Ecology. 34(21), e70025.
mla: Raffini, Francesca, et al. “Phenotypic Divergence and Genomic Architecture
between Parallel Ecotypes at Two Different Points on the Speciation Continuum
in a Marine Snail.” Molecular Ecology, vol. 34, no. 21, e70025, Wiley,
2025, doi:10.1111/mec.70025.
short: F. Raffini, A. De Jode, K. Johannesson, R. Faria, Z.B. Zagrodzka, A.M. Westram,
J. Galindo, E. Rolán-Alvarez, R.K. Butlin, Molecular Ecology 34 (2025).
date_created: 2025-08-03T22:01:31Z
date_published: 2025-11-01T00:00:00Z
date_updated: 2025-12-30T09:25:45Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.70025
external_id:
isi:
- '001538172800001'
file:
- access_level: open_access
checksum: ec01edda64cfbc6cbc8adf300f719644
content_type: application/pdf
creator: dernst
date_created: 2025-12-30T09:25:17Z
date_updated: 2025-12-30T09:25:17Z
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file_name: 2025_MolecEcology_Raffini.pdf
file_size: 2767745
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intvolume: ' 34'
isi: 1
issue: '21'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
publication: Molecular Ecology
publication_identifier:
eissn:
- 1365-294X
issn:
- 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phenotypic divergence and genomic architecture between parallel ecotypes at
two different points on the speciation continuum in a marine snail
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '19438'
abstract:
- lang: eng
text: "Polymorphic short insertions and deletions (INDELs \r\n 50 bp) are abundant,
although less common than single nucleotide polymorphisms (SNPs). Evidence from
model organisms shows INDELs to be more strongly influenced by purifying selection
than SNPs. Partly for this reason, INDELs are rarely used as markers for demographic
processes or to detect divergent selection. Here, we compared INDELs and SNPs
in the intertidal snail Littorina saxatilis, focussing on hybrid zones between
ecotypes, in order to test the utility of INDELs in the detection of divergent
selection. We computed INDEL and SNP site frequency spectra using capture sequencing
data. We assessed the impact of divergent selection by analyzing allele frequency
clines across habitat boundaries. We also examined the influence of GC-biased
gene conversion because it may be confounded with signatures of selection. We
show evidence that short INDELs are affected more by purifying selection than
SNPs, but part of the observed site frequency spectra difference can be attributed
to GC-biased gene conversion. We did not find a difference in the impact of divergent
selection between short INDELs and SNPs. Short INDELs and SNPs were similarly
distributed across the genome and so are likely to respond to indirect selection
in the same way. A few regions likely affected by divergent selection were revealed
by INDELs and not by SNPs. Short INDELs can be useful (additional) genetic markers
helping to identify genomic regions important for adaptation and population divergence."
acknowledgement: "This work was supported by the Natural Environment Research Council
(NE/K014021/1), European Research Council (ERC-2015-AdG-693030- BARRIERS) and Swedish
Research Council VR (2018-03695) and we are also very grateful for the support of
the Linnaeus Centre for Marine Evolutionary Biology at the University of Gothenburg.\r\nWe
thank the Swedish Bioinformatics Advisory Program organized by SciLifeLab for feedback
and assistance on the variant calling pipeline and Alan Le Moan for helpful discussions.
R.K.B. and A.M.W. contributed equally to this work. We are also very grateful to
Tomas Larsson and Marina Panova for their bioinformatic analyses on the genome and
the annotation. The bioinformatic analyses were performed on resources at the University
of Sheffield’s High Performance Computing cluster, ShARC. We thank two anonymous
reviewers for helpful comments on a previous version."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Samuel
full_name: Perini, Samuel
last_name: Perini
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: Perini S, Johannesson K, Butlin RK, Westram AM. Short INDELs and SNPs as markers
of evolutionary processes in hybrid zones. Journal of Evolutionary Biology.
2025;38(3):367-378. doi:10.1093/jeb/voaf002
apa: Perini, S., Johannesson, K., Butlin, R. K., & Westram, A. M. (2025). Short
INDELs and SNPs as markers of evolutionary processes in hybrid zones. Journal
of Evolutionary Biology. Oxford University Press. https://doi.org/10.1093/jeb/voaf002
chicago: Perini, Samuel, Kerstin Johannesson, Roger K. Butlin, and Anja M Westram.
“Short INDELs and SNPs as Markers of Evolutionary Processes in Hybrid Zones.”
Journal of Evolutionary Biology. Oxford University Press, 2025. https://doi.org/10.1093/jeb/voaf002.
ieee: S. Perini, K. Johannesson, R. K. Butlin, and A. M. Westram, “Short INDELs
and SNPs as markers of evolutionary processes in hybrid zones,” Journal of
Evolutionary Biology, vol. 38, no. 3. Oxford University Press, pp. 367–378,
2025.
ista: Perini S, Johannesson K, Butlin RK, Westram AM. 2025. Short INDELs and SNPs
as markers of evolutionary processes in hybrid zones. Journal of Evolutionary
Biology. 38(3), 367–378.
mla: Perini, Samuel, et al. “Short INDELs and SNPs as Markers of Evolutionary Processes
in Hybrid Zones.” Journal of Evolutionary Biology, vol. 38, no. 3, Oxford
University Press, 2025, pp. 367–78, doi:10.1093/jeb/voaf002.
short: S. Perini, K. Johannesson, R.K. Butlin, A.M. Westram, Journal of Evolutionary
Biology 38 (2025) 367–378.
corr_author: '1'
date_created: 2025-03-23T23:01:25Z
date_published: 2025-03-01T00:00:00Z
date_updated: 2025-09-30T11:19:56Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/jeb/voaf002
external_id:
isi:
- '001415267900001'
pmid:
- '39803902'
file:
- access_level: open_access
checksum: 01408e626a4131bfec5ffc70b0af9129
content_type: application/pdf
creator: dernst
date_created: 2025-04-03T11:53:06Z
date_updated: 2025-04-03T11:53:06Z
file_id: '19469'
file_name: 2025_JourEvolBiology_Perini.pdf
file_size: 12826085
relation: main_file
success: 1
file_date_updated: 2025-04-03T11:53:06Z
has_accepted_license: '1'
intvolume: ' 38'
isi: 1
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '03'
oa: 1
oa_version: Published Version
page: 367-378
pmid: 1
publication: Journal of Evolutionary Biology
publication_identifier:
eissn:
- 1420-9101
issn:
- 1010-061X
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Short INDELs and SNPs as markers of evolutionary processes in hybrid zones
tmp:
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legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 38
year: '2025'
...
---
_id: '15099'
abstract:
- lang: eng
text: Speciation is a key evolutionary process that is not yet fully understood.
Combining population genomic and ecological data from multiple diverging pairs
of marine snails (Littorina) supports the search for speciation mechanisms. Placing
pairs on a one-dimensional speciation continuum, from undifferentiated populations
to species, obscured the complexity of speciation. Adding multiple axes helped
to describe either speciation routes or reproductive isolation in the snails.
Divergent ecological selection repeatedly generated barriers between ecotypes,
but appeared less important in completing speciation while genetic incompatibilities
played a key role. Chromosomal inversions contributed to genomic barriers, but
with variable impact. A multidimensional (hypercube) approach supported framing
of questions and identification of knowledge gaps and can be useful to understand
speciation in many other systems.
acknowledgement: KJ, MR, and RKB were supported by grants from the Swedish Research
Council (2021-0419, 2021-05243, and 2018-03695, respectively). RKB was also supported
by the Leverhulme Trust (RPG-2021-141), RF by FCT- Portuguese Science Foundation
(PTDC/BIA-EVL/1614/2021 and 2020.00275.CEECIND), and AMW by Norwegian Research Council
RCN (Project number 315287). We thank the members of the Integration of Speciation
Research network for stimulating discussions, the Littorina research community for
important contributions of data and analyses, and Cynthia Riginos for useful comments
on an earlier draft.
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Alan
full_name: Le Moan, Alan
last_name: Le Moan
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
citation:
ama: Johannesson K, Faria R, Le Moan A, et al. Diverse pathways to speciation revealed
by marine snails. Trends in Genetics. 2024;40(4):337-351. doi:10.1016/j.tig.2024.01.002
apa: Johannesson, K., Faria, R., Le Moan, A., Rafajlović, M., Westram, A. M., Butlin,
R. K., & Stankowski, S. (2024). Diverse pathways to speciation revealed by
marine snails. Trends in Genetics. Elsevier. https://doi.org/10.1016/j.tig.2024.01.002
chicago: Johannesson, Kerstin, Rui Faria, Alan Le Moan, Marina Rafajlović, Anja
M Westram, Roger K. Butlin, and Sean Stankowski. “Diverse Pathways to Speciation
Revealed by Marine Snails.” Trends in Genetics. Elsevier, 2024. https://doi.org/10.1016/j.tig.2024.01.002.
ieee: K. Johannesson et al., “Diverse pathways to speciation revealed by
marine snails,” Trends in Genetics, vol. 40, no. 4. Elsevier, pp. 337–351,
2024.
ista: Johannesson K, Faria R, Le Moan A, Rafajlović M, Westram AM, Butlin RK, Stankowski
S. 2024. Diverse pathways to speciation revealed by marine snails. Trends in Genetics.
40(4), 337–351.
mla: Johannesson, Kerstin, et al. “Diverse Pathways to Speciation Revealed by Marine
Snails.” Trends in Genetics, vol. 40, no. 4, Elsevier, 2024, pp. 337–51,
doi:10.1016/j.tig.2024.01.002.
short: K. Johannesson, R. Faria, A. Le Moan, M. Rafajlović, A.M. Westram, R.K. Butlin,
S. Stankowski, Trends in Genetics 40 (2024) 337–351.
date_created: 2024-03-10T23:00:54Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-09-04T12:18:08Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1016/j.tig.2024.01.002
external_id:
isi:
- '001224671300001'
pmid:
- '38395682'
file:
- access_level: open_access
checksum: 3077ea808c4cdc24d02dc58aced7eb35
content_type: application/pdf
creator: dernst
date_created: 2024-07-22T12:05:58Z
date_updated: 2024-07-22T12:05:58Z
file_id: '17313'
file_name: 2024_TrendsGenetics_Johannesson.pdf
file_size: 2288340
relation: main_file
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issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 337-351
pmid: 1
publication: Trends in Genetics
publication_identifier:
eissn:
- 1362-4555
issn:
- 0168-9525
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Diverse pathways to speciation revealed by marine snails
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 40
year: '2024'
...
---
APC_amount: 4569,23 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '18491'
abstract:
- lang: eng
text: Predicting the outcomes of adaptation is a major goal of evolutionary biology.
When temporal changes in the environment mirror spatial gradients, it opens up
the potential for predicting the course of adaptive evolution over time based
on patterns of spatial genetic and phenotypic variation. We assessed this approach
in a 30-year transplant experiment in the intertidal snail Littorina saxatilis.
In 1992, snails were transplanted from a predation-dominated environment to one
dominated by wave action. On the basis of spatial patterns, we predicted transitions
in shell size and morphology, allele frequencies at positions throughout the genome,
and chromosomal rearrangement frequencies. Observed changes closely agreed with
predictions and transformation was both dramatic and rapid. Hence, adaptation
can be predicted from knowledge of the phenotypic and genetic variation among
populations.
acknowledgement: 'This work was received funding from the following: Norwegian Research
Council RCN project 315287 (A.M.W.), Swedish Research Council 2021-04191 (K.J.),
European Research Council grant 101055327 HaplotypeStructure (N.B.), Austrian Science
Fund FWF; P 32166-B32 Snapdragon Speciation (N.B.), European Research Council (R.B.),
and Portuguese Foundation for Science and Technology FCT: 2020.00275.CEECIND and
PTDC/BIA-EVL/1614/2021 (R.F.).'
article_number: eadp2102
article_processing_charge: Yes
article_type: original
author:
- first_name: Diego Fernando
full_name: Garcia Castillo, Diego Fernando
id: ae681a14-dc74-11ea-a0a7-c6ef18161701
last_name: Garcia Castillo
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Jenny
full_name: Larsson, Jenny
last_name: Larsson
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Predicting rapid adaptation
in time from adaptation in space: A 30-year field experiment in marine snails.
Science Advances. 2024;10(41). doi:10.1126/sciadv.adp2102'
apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski,
S., Butlin, R., … Westram, A. M. (2024). Predicting rapid adaptation in time from
adaptation in space: A 30-year field experiment in marine snails. Science Advances.
AAAS. https://doi.org/10.1126/sciadv.adp2102'
chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson,
Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Predicting
Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment
in Marine Snails.” Science Advances. AAAS, 2024. https://doi.org/10.1126/sciadv.adp2102.'
ieee: 'D. F. Garcia Castillo et al., “Predicting rapid adaptation in time
from adaptation in space: A 30-year field experiment in marine snails,” Science
Advances, vol. 10, no. 41. AAAS, 2024.'
ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R,
Johannesson K, Westram AM. 2024. Predicting rapid adaptation in time from adaptation
in space: A 30-year field experiment in marine snails. Science Advances. 10(41),
eadp2102.'
mla: 'Garcia Castillo, Diego Fernando, et al. “Predicting Rapid Adaptation in Time
from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Science
Advances, vol. 10, no. 41, eadp2102, AAAS, 2024, doi:10.1126/sciadv.adp2102.'
short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R.
Butlin, K. Johannesson, A.M. Westram, Science Advances 10 (2024).
corr_author: '1'
date_created: 2024-11-03T23:01:44Z
date_published: 2024-10-11T00:00:00Z
date_updated: 2026-04-07T11:42:09Z
day: '11'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1126/sciadv.adp2102
external_id:
isi:
- '001354405400018'
file:
- access_level: open_access
checksum: 96aa0d3640fa9401975138e59054f84e
content_type: application/pdf
creator: dernst
date_created: 2024-11-04T09:35:49Z
date_updated: 2024-11-04T09:35:49Z
file_id: '18499'
file_name: 2024_ScienceAdv_Castillo.pdf
file_size: 1154107
relation: main_file
success: 1
file_date_updated: 2024-11-04T09:35:49Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '41'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
grant_number: '101055327'
name: Understanding the evolution of continuous genomes
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
grant_number: P32166
name: Snapdragon Speciation
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
call_identifier: FWF
name: FWF Open Access Fund
publication: Science Advances
publication_identifier:
eissn:
- 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/fernandoGarcia21/littorina_saxatilis_skerry
record:
- id: '18498'
relation: research_data
status: public
- id: '20991'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: 'Predicting rapid adaptation in time from adaptation in space: A 30-year field
experiment in marine snails'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 10
year: '2024'
...
---
OA_place: repository
_id: '18498'
abstract:
- lang: eng
text: 'Scripts and data used in the research study Predicting rapid adaptation in
time from adaptation in space: a 30-year field experiment in marine snails. https://doi.org/10.1101/2023.09.27.559715'
article_processing_charge: No
author:
- first_name: Diego Fernando
full_name: Garcia Castillo, Diego Fernando
id: ae681a14-dc74-11ea-a0a7-c6ef18161701
last_name: Garcia Castillo
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Jenny
full_name: Larsson, Jenny
last_name: Larsson
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Data and code for: Predicting
rapid adaptation in time from adaptation in space: a 30-year field experiment
in marine snails. 2024. doi:10.5281/ZENODO.12159343'
apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski,
S., Butlin, R., … Westram, A. M. (2024). Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails.
Zenodo. https://doi.org/10.5281/ZENODO.12159343'
chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson,
Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Data
and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A
30-Year Field Experiment in Marine Snails.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.12159343.'
ieee: 'D. F. Garcia Castillo et al., “Data and code for: Predicting rapid
adaptation in time from adaptation in space: a 30-year field experiment in marine
snails.” Zenodo, 2024.'
ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R,
Johannesson K, Westram AM. 2024. Data and code for: Predicting rapid adaptation
in time from adaptation in space: a 30-year field experiment in marine snails,
Zenodo, 10.5281/ZENODO.12159343.'
mla: 'Garcia Castillo, Diego Fernando, et al. Data and Code for: Predicting Rapid
Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine
Snails. Zenodo, 2024, doi:10.5281/ZENODO.12159343.'
short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R.
Butlin, K. Johannesson, A.M. Westram, (2024).
corr_author: '1'
date_created: 2024-11-04T09:33:17Z
date_published: 2024-06-19T00:00:00Z
date_updated: 2026-04-16T12:20:37Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5281/ZENODO.12159343
has_accepted_license: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.5281/zenodo.12159344
month: '06'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
record:
- id: '20991'
relation: used_in_publication
status: public
- id: '18491'
relation: used_in_publication
status: public
status: public
title: 'Data and code for: Predicting rapid adaptation in time from adaptation in
space: a 30-year field experiment in marine snails'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '14796'
abstract:
- lang: eng
text: Key innovations are fundamental to biological diversification, but their genetic
basis is poorly understood. A recent transition from egg-laying to live-bearing
in marine snails (Littorina spp.) provides the opportunity to study the genetic
architecture of an innovation that has evolved repeatedly across animals. Individuals
do not cluster by reproductive mode in a genome-wide phylogeny, but local genealogical
analysis revealed numerous small genomic regions where all live-bearers carry
the same core haplotype. Candidate regions show evidence for live-bearer–specific
positive selection and are enriched for genes that are differentially expressed
between egg-laying and live-bearing reproductive systems. Ages of selective sweeps
suggest that live-bearer–specific alleles accumulated over more than 200,000 generations.
Our results suggest that new functions evolve through the recruitment of many
alleles rather than in a single evolutionary step.
acknowledgement: "We thank J. Galindo, M. Montaño-Rendón, N. Mikhailova, A. Blakeslee,
E. Arnason, and P. Kemppainen for providing samples; R. Turney, G. Sotelo, J. Larsson,
T. Broquet, and S. Loisel for help collecting samples; Science Animated for providing
the snail cartoons shown in Fig. 1; M. Dunning for help in developing bioinformatic
pipelines; R. Faria, H. Morales, and V. Sousa for advice; and M. Hahn, J. Slate,
M. Ravinet, J. Raeymaekers, A. Comeault, and N. Barton for feedback on a draft manuscript.\r\nThis
work was supported by the Natural Environment Research Council (grant NE/P001610/1
to R.K.B.), the European Research Council (grant ERC-2015-AdG693030-BARRIERS to
R.K.B.), the Norwegian Research Council (RCN Project 315287 to A.M.W.), and the
Swedish Research Council (grant 2020-05385 to E.L.)."
article_processing_charge: No
article_type: original
author:
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Zuzanna B.
full_name: Zagrodzka, Zuzanna B.
last_name: Zagrodzka
- first_name: Martin D.
full_name: Garlovsky, Martin D.
last_name: Garlovsky
- first_name: Arka
full_name: Pal, Arka
id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
last_name: Pal
orcid: 0000-0002-4530-8469
- first_name: Daria
full_name: Shipilina, Daria
id: 428A94B0-F248-11E8-B48F-1D18A9856A87
last_name: Shipilina
orcid: 0000-0002-1145-9226
- first_name: Diego Fernando
full_name: Garcia Castillo, Diego Fernando
id: ae681a14-dc74-11ea-a0a7-c6ef18161701
last_name: Garcia Castillo
- first_name: Hila
full_name: Lifchitz, Hila
id: d6ab5470-2fb3-11ed-8633-986a9b84edac
last_name: Lifchitz
- first_name: Alan
full_name: Le Moan, Alan
last_name: Le Moan
- first_name: Erica
full_name: Leder, Erica
last_name: Leder
- first_name: James
full_name: Reeve, James
last_name: Reeve
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: Stankowski S, Zagrodzka ZB, Garlovsky MD, et al. The genetic basis of a recent
transition to live-bearing in marine snails. Science. 2024;383(6678):114-119.
doi:10.1126/science.adi2982
apa: Stankowski, S., Zagrodzka, Z. B., Garlovsky, M. D., Pal, A., Shipilina, D.,
Garcia Castillo, D. F., … Butlin, R. K. (2024). The genetic basis of a recent
transition to live-bearing in marine snails. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.adi2982
chicago: Stankowski, Sean, Zuzanna B. Zagrodzka, Martin D. Garlovsky, Arka Pal,
Daria Shipilina, Diego Fernando Garcia Castillo, Hila Lifchitz, et al. “The Genetic
Basis of a Recent Transition to Live-Bearing in Marine Snails.” Science.
American Association for the Advancement of Science, 2024. https://doi.org/10.1126/science.adi2982.
ieee: S. Stankowski et al., “The genetic basis of a recent transition to
live-bearing in marine snails,” Science, vol. 383, no. 6678. American Association
for the Advancement of Science, pp. 114–119, 2024.
ista: Stankowski S, Zagrodzka ZB, Garlovsky MD, Pal A, Shipilina D, Garcia Castillo
DF, Lifchitz H, Le Moan A, Leder E, Reeve J, Johannesson K, Westram AM, Butlin
RK. 2024. The genetic basis of a recent transition to live-bearing in marine snails.
Science. 383(6678), 114–119.
mla: Stankowski, Sean, et al. “The Genetic Basis of a Recent Transition to Live-Bearing
in Marine Snails.” Science, vol. 383, no. 6678, American Association for
the Advancement of Science, 2024, pp. 114–19, doi:10.1126/science.adi2982.
short: S. Stankowski, Z.B. Zagrodzka, M.D. Garlovsky, A. Pal, D. Shipilina, D.F.
Garcia Castillo, H. Lifchitz, A. Le Moan, E. Leder, J. Reeve, K. Johannesson,
A.M. Westram, R.K. Butlin, Science 383 (2024) 114–119.
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-05T00:00:00Z
date_updated: 2026-04-28T22:31:10Z
day: '05'
department:
- _id: NiBa
- _id: GradSch
doi: 10.1126/science.adi2982
external_id:
isi:
- '001138156400003'
pmid:
- '38175895'
intvolume: ' 383'
isi: 1
issue: '6678'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://figshare.com/articles/journal_contribution/The_genetic_basis_of_a_recent_transition_to_live-bearing_in_marine_snails/26356054?file=47868241
month: '01'
oa: 1
oa_version: Submitted Version
page: 114-119
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
link:
- description: News on ISTA Website
relation: press_release
url: https://ista.ac.at/en/news/the-snail-or-the-egg/
record:
- id: '14812'
relation: research_data
status: public
- id: '20694'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: The genetic basis of a recent transition to live-bearing in marine snails
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 383
year: '2024'
...
---
_id: '11479'
abstract:
- lang: eng
text: Understanding population divergence that eventually leads to speciation is
essential for evolutionary biology. High species diversity in the sea was regarded
as a paradox when strict allopatry was considered necessary for most speciation
events because geographical barriers seemed largely absent in the sea, and many
marine species have high dispersal capacities. Combining genome-wide data with
demographic modelling to infer the demographic history of divergence has introduced
new ways to address this classical issue. These models assume an ancestral population
that splits into two subpopulations diverging according to different scenarios
that allow tests for periods of gene flow. Models can also test for heterogeneities
in population sizes and migration rates along the genome to account, respectively,
for background selection and selection against introgressed ancestry. To investigate
how barriers to gene flow arise in the sea, we compiled studies modelling the
demographic history of divergence in marine organisms and extracted preferred
demographic scenarios together with estimates of demographic parameters. These
studies show that geographical barriers to gene flow do exist in the sea but that
divergence can also occur without strict isolation. Heterogeneity of gene flow
was detected in most population pairs suggesting the predominance of semipermeable
barriers during divergence. We found a weak positive relationship between the
fraction of the genome experiencing reduced gene flow and levels of genome-wide
differentiation. Furthermore, we found that the upper bound of the ‘grey zone
of speciation’ for our dataset extended beyond that found before, implying that
gene flow between diverging taxa is possible at higher levels of divergence than
previously thought. Finally, we list recommendations for further strengthening
the use of demographic modelling in speciation research. These include a more
balanced representation of taxa, more consistent and comprehensive modelling,
clear reporting of results and simulation studies to rule out nonbiological explanations
for general results.
acknowledgement: 'We greatly thank all the corresponding authors of the studies that
were included in our synthesis for the sharing of additional data: Thomas Broquet,
Dmitry Filatov, Quentin Rougemont, Paolo Momigliano, Pierre-Alexandre Gagnaire,
Carlos Prada, Ahmed Souissi, Michael Møller Hansen, Sylvie Lapègue, Joseph Di Battista,
Michael Hellberg and Carlos Prada. RKB and ADJ were supported by the European Research
Council. MR was supported by the Swedish Research Council Vetenskapsrådet (grant
number 2021-05243; to MR) and Formas (grant number 2019-00882; to KJ and MR), and
by additional grants from the European Research Council (to RKB) and Vetenskapsrådet
(to KJ) through the Centre for Marine Evolutionary Biology (https://www.gu.se/en/cemeb-marine-evolutionary-biology).'
article_processing_charge: No
article_type: original
author:
- first_name: Aurélien
full_name: De Jode, Aurélien
last_name: De Jode
- first_name: Alan
full_name: Le Moan, Alan
last_name: Le Moan
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Christelle
full_name: Fraisse, Christelle
id: 32DF5794-F248-11E8-B48F-1D18A9856A87
last_name: Fraisse
orcid: 0000-0001-8441-5075
citation:
ama: De Jode A, Le Moan A, Johannesson K, et al. Ten years of demographic modelling
of divergence and speciation in the sea. Evolutionary Applications. 2023;16(2):542-559.
doi:10.1111/eva.13428
apa: De Jode, A., Le Moan, A., Johannesson, K., Faria, R., Stankowski, S., Westram,
A. M., … Fraisse, C. (2023). Ten years of demographic modelling of divergence
and speciation in the sea. Evolutionary Applications. Wiley. https://doi.org/10.1111/eva.13428
chicago: De Jode, Aurélien, Alan Le Moan, Kerstin Johannesson, Rui Faria, Sean Stankowski,
Anja M Westram, Roger K. Butlin, Marina Rafajlović, and Christelle Fraisse. “Ten
Years of Demographic Modelling of Divergence and Speciation in the Sea.” Evolutionary
Applications. Wiley, 2023. https://doi.org/10.1111/eva.13428.
ieee: A. De Jode et al., “Ten years of demographic modelling of divergence
and speciation in the sea,” Evolutionary Applications, vol. 16, no. 2.
Wiley, pp. 542–559, 2023.
ista: De Jode A, Le Moan A, Johannesson K, Faria R, Stankowski S, Westram AM, Butlin
RK, Rafajlović M, Fraisse C. 2023. Ten years of demographic modelling of divergence
and speciation in the sea. Evolutionary Applications. 16(2), 542–559.
mla: De Jode, Aurélien, et al. “Ten Years of Demographic Modelling of Divergence
and Speciation in the Sea.” Evolutionary Applications, vol. 16, no. 2,
Wiley, 2023, pp. 542–59, doi:10.1111/eva.13428.
short: A. De Jode, A. Le Moan, K. Johannesson, R. Faria, S. Stankowski, A.M. Westram,
R.K. Butlin, M. Rafajlović, C. Fraisse, Evolutionary Applications 16 (2023) 542–559.
date_created: 2022-07-03T22:01:33Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2025-04-23T08:49:14Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
- _id: BeVi
doi: 10.1111/eva.13428
external_id:
isi:
- '000815663700001'
pmid:
- '36793688'
file:
- access_level: open_access
checksum: d4d6fa9ddf36643af994a6a757919afb
content_type: application/pdf
creator: dernst
date_created: 2023-02-27T07:10:17Z
date_updated: 2023-02-27T07:10:17Z
file_id: '12685'
file_name: 2023_EvolutionaryApplications_DeJode.pdf
file_size: 2269822
relation: main_file
success: 1
file_date_updated: 2023-02-27T07:10:17Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 542-559
pmid: 1
publication: Evolutionary Applications
publication_identifier:
eissn:
- 1752-4571
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ten years of demographic modelling of divergence and speciation in the sea
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2023'
...
---
OA_type: free access
_id: '12166'
abstract:
- lang: eng
text: Kerstin Johannesson is a marine ecologist and evolutionary biologist based
at the Tjärnö Marine Laboratory of the University of Gothenburg, which is situated
in the beautiful Kosterhavet National Park on the Swedish west coast. Her work,
using marine periwinkles (especially Littorina saxatilis and L. fabalis) as main
model systems, has made a remarkable contribution to marine evolutionary biology
and our understanding of local adaptation and its genetic underpinnings.
article_processing_charge: No
article_type: editorial
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: Westram AM, Butlin R. Professor Kerstin Johannesson–winner of the 2022 Molecular
Ecology Prize. Molecular Ecology. 2023;32(1):26-29. doi:10.1111/mec.16779
apa: Westram, A. M., & Butlin, R. (2023). Professor Kerstin Johannesson–winner
of the 2022 Molecular Ecology Prize. Molecular Ecology. Wiley. https://doi.org/10.1111/mec.16779
chicago: Westram, Anja M, and Roger Butlin. “Professor Kerstin Johannesson–Winner
of the 2022 Molecular Ecology Prize.” Molecular Ecology. Wiley, 2023. https://doi.org/10.1111/mec.16779.
ieee: A. M. Westram and R. Butlin, “Professor Kerstin Johannesson–winner of the
2022 Molecular Ecology Prize,” Molecular Ecology, vol. 32, no. 1. Wiley,
pp. 26–29, 2023.
ista: Westram AM, Butlin R. 2023. Professor Kerstin Johannesson–winner of the 2022
Molecular Ecology Prize. Molecular Ecology. 32(1), 26–29.
mla: Westram, Anja M., and Roger Butlin. “Professor Kerstin Johannesson–Winner of
the 2022 Molecular Ecology Prize.” Molecular Ecology, vol. 32, no. 1, Wiley,
2023, pp. 26–29, doi:10.1111/mec.16779.
short: A.M. Westram, R. Butlin, Molecular Ecology 32 (2023) 26–29.
corr_author: '1'
date_created: 2023-01-12T12:10:28Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2025-04-23T08:44:33Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/mec.16779
external_id:
isi:
- '000892168800001'
pmid:
- '36443277'
intvolume: ' 32'
isi: 1
issue: '1'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1111/mec.16779
month: '01'
oa: 1
oa_version: Published Version
page: 26-29
pmid: 1
publication: Molecular Ecology
publication_identifier:
eissn:
- 1365-294X
issn:
- 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Professor Kerstin Johannesson–winner of the 2022 Molecular Ecology Prize
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2023'
...
---
_id: '14556'
abstract:
- lang: eng
text: Inversions are structural mutations that reverse the sequence of a chromosome
segment and reduce the effective rate of recombination in the heterozygous state.
They play a major role in adaptation, as well as in other evolutionary processes
such as speciation. Although inversions have been studied since the 1920s, they
remain difficult to investigate because the reduced recombination conferred by
them strengthens the effects of drift and hitchhiking, which in turn can obscure
signatures of selection. Nonetheless, numerous inversions have been found to be
under selection. Given recent advances in population genetic theory and empirical
study, here we review how different mechanisms of selection affect the evolution
of inversions. A key difference between inversions and other mutations, such as
single nucleotide variants, is that the fitness of an inversion may be affected
by a larger number of frequently interacting processes. This considerably complicates
the analysis of the causes underlying the evolution of inversions. We discuss
the extent to which these mechanisms can be disentangled, and by which approach.
acknowledgement: 'We are grateful to two referees and Luke Holman for valuable comments
on a previous version of our manuscript. This paper was conceived at the ESEB Progress
Meeting ‘Disentangling neutral versus adaptive evolution in chromosomal inversions’,
organized by ELB, KJ and TF and held at Tjärnö Marine Laboratory (Sweden) between
28 February and 3 March 2022. We are indebted to ESEB for sponsoring our workshop
and to the following funding bodies for supporting our research: ERC AdG 101055327
to NHB; Swedish Research Council (VR) 2018-03695 and Leverhulme Trust RPG-2021-141
to RKB; Fundação para a Ciência e a Tecnologia (FCT) contract 2020.00275.CEECIND
and research project PTDC/BIA-1232 EVL/1614/2021 to RF; Fundação para a Ciência
e a Tecnologia (FCT) junior researcher contract CEECIND/02616/2018 to IF; Swiss
National Science Foundation (SNSF) Ambizione #PZ00P3_185952 to KJG; National Science
Foundation NSF-OCE 2043905 and NSF-DEB 1655701 to KEL; Swiss National Science Foundation
(SNSF) 310030_204681 to CLP; Swedish Research Council (VR) 2021-05243 to MR; Norwegian
Research Council grant 315287 to AMW; Swiss National Science Foundation (SNSF) 31003A-182262
and FZEB-0-214654 to TF. We also thank Luca Ferretti for the discussion and Eliane
Zinn (Flatt lab) for help with reference formatting.'
article_number: '14242'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Emma L.
full_name: Berdan, Emma L.
last_name: Berdan
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Inês
full_name: Fragata, Inês
last_name: Fragata
- first_name: Kimberly J.
full_name: Gilbert, Kimberly J.
last_name: Gilbert
- first_name: Paul
full_name: Jay, Paul
last_name: Jay
- first_name: Martin
full_name: Kapun, Martin
last_name: Kapun
- first_name: Katie E.
full_name: Lotterhos, Katie E.
last_name: Lotterhos
- first_name: Claire
full_name: Mérot, Claire
last_name: Mérot
- first_name: Esra
full_name: Durmaz Mitchell, Esra
last_name: Durmaz Mitchell
- first_name: Marta
full_name: Pascual, Marta
last_name: Pascual
- first_name: Catherine L.
full_name: Peichel, Catherine L.
last_name: Peichel
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Stephen W.
full_name: Schaeffer, Stephen W.
last_name: Schaeffer
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Thomas
full_name: Flatt, Thomas
last_name: Flatt
citation:
ama: Berdan EL, Barton NH, Butlin R, et al. How chromosomal inversions reorient
the evolutionary process. Journal of Evolutionary Biology. 2023;36(12).
doi:10.1111/jeb.14242
apa: Berdan, E. L., Barton, N. H., Butlin, R., Charlesworth, B., Faria, R., Fragata,
I., … Flatt, T. (2023). How chromosomal inversions reorient the evolutionary process.
Journal of Evolutionary Biology. Wiley. https://doi.org/10.1111/jeb.14242
chicago: Berdan, Emma L., Nicholas H Barton, Roger Butlin, Brian Charlesworth, Rui
Faria, Inês Fragata, Kimberly J. Gilbert, et al. “How Chromosomal Inversions Reorient
the Evolutionary Process.” Journal of Evolutionary Biology. Wiley, 2023.
https://doi.org/10.1111/jeb.14242.
ieee: E. L. Berdan et al., “How chromosomal inversions reorient the evolutionary
process,” Journal of Evolutionary Biology, vol. 36, no. 12. Wiley, 2023.
ista: Berdan EL, Barton NH, Butlin R, Charlesworth B, Faria R, Fragata I, Gilbert
KJ, Jay P, Kapun M, Lotterhos KE, Mérot C, Durmaz Mitchell E, Pascual M, Peichel
CL, Rafajlović M, Westram AM, Schaeffer SW, Johannesson K, Flatt T. 2023. How
chromosomal inversions reorient the evolutionary process. Journal of Evolutionary
Biology. 36(12), 14242.
mla: Berdan, Emma L., et al. “How Chromosomal Inversions Reorient the Evolutionary
Process.” Journal of Evolutionary Biology, vol. 36, no. 12, 14242, Wiley,
2023, doi:10.1111/jeb.14242.
short: E.L. Berdan, N.H. Barton, R. Butlin, B. Charlesworth, R. Faria, I. Fragata,
K.J. Gilbert, P. Jay, M. Kapun, K.E. Lotterhos, C. Mérot, E. Durmaz Mitchell,
M. Pascual, C.L. Peichel, M. Rafajlović, A.M. Westram, S.W. Schaeffer, K. Johannesson,
T. Flatt, Journal of Evolutionary Biology 36 (2023).
date_created: 2023-11-19T23:00:55Z
date_published: 2023-12-01T00:00:00Z
date_updated: 2025-09-09T13:22:35Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/jeb.14242
external_id:
isi:
- '001098690500001'
pmid:
- '37942504'
file:
- access_level: open_access
checksum: 93ae4fa700aab8646bc62f0adeed8f8f
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T08:16:31Z
date_updated: 2024-07-16T08:16:31Z
file_id: '17253'
file_name: 2023_JourEvolutionaryBio_Berdan.pdf
file_size: 1401726
relation: main_file
success: 1
file_date_updated: 2024-07-16T08:16:31Z
has_accepted_license: '1'
intvolume: ' 36'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Evolutionary Biology
publication_identifier:
eissn:
- 1420-9101
issn:
- 1010-061X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: How chromosomal inversions reorient the evolutionary process
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 36
year: '2023'
...
---
_id: '14742'
abstract:
- lang: eng
text: "Chromosomal rearrangements (CRs) have been known since almost the beginning
of genetics.\r\nWhile an important role for CRs in speciation has been suggested,
evidence primarily stems\r\nfrom theoretical and empirical studies focusing on
the microevolutionary level (i.e., on taxon\r\npairs where speciation is often
incomplete). Although the role of CRs in eukaryotic speciation at\r\na macroevolutionary
level has been supported by associations between species diversity and\r\nrates
of evolution of CRs across phylogenies, these findings are limited to a restricted
range of\r\nCRs and taxa. Now that more broadly applicable and precise CR detection
approaches have\r\nbecome available, we address the challenges in filling some
of the conceptual and empirical\r\ngaps between micro- and macroevolutionary studies
on the role of CRs in speciation. We\r\nsynthesize what is known about the macroevolutionary
impact of CRs and suggest new research avenues to overcome the pitfalls of previous
studies to gain a more comprehensive understanding of the evolutionary significance
of CRs in speciation across the tree of life."
acknowledgement: "K.L. was funded by a Swiss National Science Foundation Eccellenza
project: The evolution of strong reproductive barriers towards the completion of
speciation (PCEFP3_202869). R.F.\r\nwas funded by an FCT CEEC (Fundação para a Ciênca
e a Tecnologia, Concurso Estímulo ao\r\nEmprego Científico) contract (2020.00275.
CEECIND) and by an FCT research project\r\n(PTDC/BIA-EVL/1614/2021). M.R. was funded
by the Swedish Research Council Vetenskapsrådet (grant number 2021-05243). A.M.W.
was partly funded by the Norwegian Research Council RCN. We thank Luis Silva for
his help preparing Figure 1. We are grateful to Maren Wellenreuther, Daniel Bolnick,
and two anonymous reviewers for their constructive feedback on an earlier version
of this paper."
article_number: a041447
article_processing_charge: No
article_type: original
author:
- first_name: Kay
full_name: Lucek, Kay
last_name: Lucek
- first_name: Mabel D.
full_name: Giménez, Mabel D.
last_name: Giménez
- first_name: Mathieu
full_name: Joron, Mathieu
last_name: Joron
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Jeremy B.
full_name: Searle, Jeremy B.
last_name: Searle
- first_name: Nora
full_name: Walden, Nora
last_name: Walden
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
citation:
ama: 'Lucek K, Giménez MD, Joron M, et al. The impact of chromosomal rearrangements
in speciation: From micro- to macroevolution. Cold Spring Harbor Perspectives
in Biology. 2023;15(11). doi:10.1101/cshperspect.a041447'
apa: 'Lucek, K., Giménez, M. D., Joron, M., Rafajlović, M., Searle, J. B., Walden,
N., … Faria, R. (2023). The impact of chromosomal rearrangements in speciation:
From micro- to macroevolution. Cold Spring Harbor Perspectives in Biology.
Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/cshperspect.a041447'
chicago: 'Lucek, Kay, Mabel D. Giménez, Mathieu Joron, Marina Rafajlović, Jeremy
B. Searle, Nora Walden, Anja M Westram, and Rui Faria. “The Impact of Chromosomal
Rearrangements in Speciation: From Micro- to Macroevolution.” Cold Spring Harbor
Perspectives in Biology. Cold Spring Harbor Laboratory Press, 2023. https://doi.org/10.1101/cshperspect.a041447.'
ieee: 'K. Lucek et al., “The impact of chromosomal rearrangements in speciation:
From micro- to macroevolution,” Cold Spring Harbor Perspectives in Biology,
vol. 15, no. 11. Cold Spring Harbor Laboratory Press, 2023.'
ista: 'Lucek K, Giménez MD, Joron M, Rafajlović M, Searle JB, Walden N, Westram
AM, Faria R. 2023. The impact of chromosomal rearrangements in speciation: From
micro- to macroevolution. Cold Spring Harbor Perspectives in Biology. 15(11),
a041447.'
mla: 'Lucek, Kay, et al. “The Impact of Chromosomal Rearrangements in Speciation:
From Micro- to Macroevolution.” Cold Spring Harbor Perspectives in Biology,
vol. 15, no. 11, a041447, Cold Spring Harbor Laboratory Press, 2023, doi:10.1101/cshperspect.a041447.'
short: K. Lucek, M.D. Giménez, M. Joron, M. Rafajlović, J.B. Searle, N. Walden,
A.M. Westram, R. Faria, Cold Spring Harbor Perspectives in Biology 15 (2023).
date_created: 2024-01-08T12:43:48Z
date_published: 2023-11-01T00:00:00Z
date_updated: 2025-09-09T14:09:32Z
day: '01'
department:
- _id: NiBa
- _id: BeVi
doi: 10.1101/cshperspect.a041447
external_id:
isi:
- '001096272600001'
pmid:
- '37604585'
intvolume: ' 15'
isi: 1
issue: '11'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/cshperspect.a041447
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cold Spring Harbor Perspectives in Biology
publication_identifier:
issn:
- 1943-0264
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The impact of chromosomal rearrangements in speciation: From micro- to macroevolution'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2023'
...
---
_id: '14833'
abstract:
- lang: eng
text: Understanding the factors that have shaped the current distributions and diversity
of species is a central and longstanding aim of evolutionary biology. The recent
inclusion of genomic data into phylogeographic studies has dramatically improved
our understanding in organisms where evolutionary relationships have been challenging
to infer. We used whole-genome sequences to study the phylogeography of the intertidal
snail Littorina saxatilis, which has successfully colonized and diversified across
a broad range of coastal environments in the Northern Hemisphere amid repeated
cycles of glaciation. Building on past studies based on short DNA sequences, we
used genome-wide data to provide a clearer picture of the relationships among
samples spanning most of the species natural range. Our results confirm the trans-Atlantic
colonization of North America from Europe, and have allowed us to identify rough
locations of glacial refugia and to infer likely routes of colonization within
Europe. We also investigated the signals in different datasets to account for
the effects of genomic architecture and non-neutral evolution, which provides
new insights about diversification of four ecotypes of L. saxatilis (the crab,
wave, barnacle, and brackish ecotypes) at different spatial scales. Overall, we
provide a much clearer picture of the biogeography of L. saxatilis, providing
a foundation for more detailed phylogenomic and demographic studies.
acknowledgement: Isobel Eyres, Richard Turney, Graciela Sotelo, Jenny Larson, and
Stéphane Loisel helped with the collection and processing of samples. Petri Kemppainen
kindly provided samples from Trondheim Fjord. Mark Dunning helped with the development
of bioinformatic pipelines. The analysis of genomic data was conducted on the University
of Sheffield high-performance computing cluster, ShARC. Funding was provided by
the Natural Environment Research Council (NERC) and the European Research Council
(ERC). J.G. was funded by a Juntas Industriales y Navales (JIN) project (Ministerio
de Ciencia, Innovación y Universidades, code RTI2018-101274-J-I00).
article_number: kzad002
article_processing_charge: Yes
article_type: original
author:
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Zuzanna B
full_name: Zagrodzka, Zuzanna B
last_name: Zagrodzka
- first_name: Juan
full_name: Galindo, Juan
last_name: Galindo
- first_name: Mauricio
full_name: Montaño-Rendón, Mauricio
last_name: Montaño-Rendón
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Natalia
full_name: Mikhailova, Natalia
last_name: Mikhailova
- first_name: April M H
full_name: Blakeslee, April M H
last_name: Blakeslee
- first_name: Einar
full_name: Arnason, Einar
last_name: Arnason
- first_name: Thomas
full_name: Broquet, Thomas
last_name: Broquet
- first_name: Hernán E
full_name: Morales, Hernán E
last_name: Morales
- first_name: John W
full_name: Grahame, John W
last_name: Grahame
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger K
full_name: Butlin, Roger K
last_name: Butlin
citation:
ama: Stankowski S, Zagrodzka ZB, Galindo J, et al. Whole-genome phylogeography of
the intertidal snail Littorina saxatilis. Evolutionary Journal of the Linnean
Society. 2023;2(1). doi:10.1093/evolinnean/kzad002
apa: Stankowski, S., Zagrodzka, Z. B., Galindo, J., Montaño-Rendón, M., Faria, R.,
Mikhailova, N., … Butlin, R. K. (2023). Whole-genome phylogeography of the intertidal
snail Littorina saxatilis. Evolutionary Journal of the Linnean Society.
Oxford University Press. https://doi.org/10.1093/evolinnean/kzad002
chicago: Stankowski, Sean, Zuzanna B Zagrodzka, Juan Galindo, Mauricio Montaño-Rendón,
Rui Faria, Natalia Mikhailova, April M H Blakeslee, et al. “Whole-Genome Phylogeography
of the Intertidal Snail Littorina Saxatilis.” Evolutionary Journal of the Linnean
Society. Oxford University Press, 2023. https://doi.org/10.1093/evolinnean/kzad002.
ieee: S. Stankowski et al., “Whole-genome phylogeography of the intertidal
snail Littorina saxatilis,” Evolutionary Journal of the Linnean Society,
vol. 2, no. 1. Oxford University Press, 2023.
ista: Stankowski S, Zagrodzka ZB, Galindo J, Montaño-Rendón M, Faria R, Mikhailova
N, Blakeslee AMH, Arnason E, Broquet T, Morales HE, Grahame JW, Westram AM, Johannesson
K, Butlin RK. 2023. Whole-genome phylogeography of the intertidal snail Littorina
saxatilis. Evolutionary Journal of the Linnean Society. 2(1), kzad002.
mla: Stankowski, Sean, et al. “Whole-Genome Phylogeography of the Intertidal Snail
Littorina Saxatilis.” Evolutionary Journal of the Linnean Society, vol.
2, no. 1, kzad002, Oxford University Press, 2023, doi:10.1093/evolinnean/kzad002.
short: S. Stankowski, Z.B. Zagrodzka, J. Galindo, M. Montaño-Rendón, R. Faria, N.
Mikhailova, A.M.H. Blakeslee, E. Arnason, T. Broquet, H.E. Morales, J.W. Grahame,
A.M. Westram, K. Johannesson, R.K. Butlin, Evolutionary Journal of the Linnean
Society 2 (2023).
corr_author: '1'
date_created: 2024-01-18T07:54:10Z
date_published: 2023-08-17T00:00:00Z
date_updated: 2024-10-09T21:07:54Z
day: '17'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1093/evolinnean/kzad002
file:
- access_level: open_access
checksum: ba6f9102d3a9fe6631c4fa398c5e4313
content_type: application/pdf
creator: dernst
date_created: 2024-01-23T08:10:00Z
date_updated: 2024-01-23T08:10:00Z
file_id: '14875'
file_name: 2023_EvolJourLinneanSociety_Stankowski.pdf
file_size: 3408944
relation: main_file
success: 1
file_date_updated: 2024-01-23T08:10:00Z
has_accepted_license: '1'
intvolume: ' 2'
issue: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Evolutionary Journal of the Linnean Society
publication_identifier:
eissn:
- 2752-938X
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: Whole-genome phylogeography of the intertidal snail Littorina saxatilis
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2023'
...
---
_id: '11546'
abstract:
- lang: eng
text: Local adaptation leads to differences between populations within a species.
In many systems, similar environmental contrasts occur repeatedly, sometimes driving
parallel phenotypic evolution. Understanding the genomic basis of local adaptation
and parallel evolution is a major goal of evolutionary genomics. It is now known
that by preventing the break-up of favourable combinations of alleles across multiple
loci, genetic architectures that reduce recombination, like chromosomal inversions,
can make an important contribution to local adaptation. However, little is known
about whether inversions also contribute disproportionately to parallel evolution.
Our aim here is to highlight this knowledge gap, to showcase existing studies,
and to illustrate the differences between genomic architectures with and without
inversions using simple models. We predict that by generating stronger effective
selection, inversions can sometimes speed up the parallel adaptive process or
enable parallel adaptation where it would be impossible otherwise, but this is
highly dependent on the spatial setting. We highlight that further empirical work
is needed, in particular to cover a broader taxonomic range and to understand
the relative importance of inversions compared to genomic regions without inversions.
acknowledgement: We thank the editor and two anonymous reviewers for their helpful
and interesting comments on this manuscript.
article_number: '20210203'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Westram AM, Faria R, Johannesson K, Butlin R, Barton NH. Inversions and parallel
evolution. Philosophical Transactions of the Royal Society B: Biological Sciences.
2022;377(1856). doi:10.1098/rstb.2021.0203'
apa: 'Westram, A. M., Faria, R., Johannesson, K., Butlin, R., & Barton, N. H.
(2022). Inversions and parallel evolution. Philosophical Transactions of the
Royal Society B: Biological Sciences. Royal Society of London. https://doi.org/10.1098/rstb.2021.0203'
chicago: 'Westram, Anja M, Rui Faria, Kerstin Johannesson, Roger Butlin, and Nicholas
H Barton. “Inversions and Parallel Evolution.” Philosophical Transactions of
the Royal Society B: Biological Sciences. Royal Society of London, 2022. https://doi.org/10.1098/rstb.2021.0203.'
ieee: 'A. M. Westram, R. Faria, K. Johannesson, R. Butlin, and N. H. Barton, “Inversions
and parallel evolution,” Philosophical Transactions of the Royal Society B:
Biological Sciences, vol. 377, no. 1856. Royal Society of London, 2022.'
ista: 'Westram AM, Faria R, Johannesson K, Butlin R, Barton NH. 2022. Inversions
and parallel evolution. Philosophical Transactions of the Royal Society B: Biological
Sciences. 377(1856), 20210203.'
mla: 'Westram, Anja M., et al. “Inversions and Parallel Evolution.” Philosophical
Transactions of the Royal Society B: Biological Sciences, vol. 377, no. 1856,
20210203, Royal Society of London, 2022, doi:10.1098/rstb.2021.0203.'
short: 'A.M. Westram, R. Faria, K. Johannesson, R. Butlin, N.H. Barton, Philosophical
Transactions of the Royal Society B: Biological Sciences 377 (2022).'
corr_author: '1'
date_created: 2022-07-08T11:41:56Z
date_published: 2022-08-01T00:00:00Z
date_updated: 2025-06-12T06:10:18Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1098/rstb.2021.0203
external_id:
isi:
- '000812317300005'
pmid:
- '35694747'
file:
- access_level: open_access
checksum: 49f69428f3dcf5ce3ff281f7d199e9df
content_type: application/pdf
creator: dernst
date_created: 2023-02-02T08:20:29Z
date_updated: 2023-02-02T08:20:29Z
file_id: '12479'
file_name: 2022_PhilosophicalTransactionsB_Westram.pdf
file_size: 920304
relation: main_file
success: 1
file_date_updated: 2023-02-02T08:20:29Z
has_accepted_license: '1'
intvolume: ' 377'
isi: 1
issue: '1856'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
grant_number: P32166
name: Snapdragon Speciation
publication: 'Philosophical Transactions of the Royal Society B: Biological Sciences'
publication_identifier:
eissn:
- 1471-2970
issn:
- 0962-8436
publication_status: published
publisher: Royal Society of London
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inversions and parallel evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 377
year: '2022'
...
---
_id: '12001'
abstract:
- lang: eng
text: 'Sexual antagonism is a common hypothesis for driving the evolution of sex
chromosomes, whereby recombination suppression is favored between sexually antagonistic
loci and the sex-determining locus to maintain beneficial combinations of alleles.
This results in the formation of a sex-determining region. Chromosomal inversions
may contribute to recombination suppression but their precise role in sex chromosome
evolution remains unclear. Because local adaptation is frequently facilitated
through the suppression of recombination between adaptive loci by chromosomal
inversions, there is potential for inversions that cover sex-determining regions
to be involved in local adaptation as well, particularly if habitat variation
creates environment-dependent sexual antagonism. With these processes in mind,
we investigated sex determination in a well-studied example of local adaptation
within a species: the intertidal snail, Littorina saxatilis. Using SNP data from
a Swedish hybrid zone, we find novel evidence for a female-heterogametic sex determination
system that is restricted to one ecotype. Our results suggest that four putative
chromosomal inversions, two previously described and two newly discovered, span
the putative sex chromosome pair. We determine their differing associations with
sex, which suggest distinct strata of differing ages. The same inversions are
found in the second ecotype but do not show any sex association. The striking
disparity in inversion-sex associations between ecotypes that are connected by
gene flow across a habitat transition that is just a few meters wide indicates
a difference in selective regime that has produced a distinct barrier to the spread
of the newly discovered sex-determining region between ecotypes. Such sex chromosome-environment
interactions have not previously been uncovered in L. saxatilis and are known
in few other organisms. A combination of both sex-specific selection and divergent
natural selection is required to explain these highly unusual patterns.'
acknowledgement: We thank A. Wright and four anonymous reviewers for valuable comments
on an earlier draft of this manuscript and all members of the Littorina group for
helpful discussions. This work was supported by a European Research Council grant
to RKB and by a Natural Environment Research Council studentship to KEH through
the ACCE doctoral training program. KJ acknowledges support from the Swedish Science
Research Council VR (Vetenskaprådet) (2017-03798). RF was supported by an FCT CEEC
(Fundação para a Ciênca e a Tecnologia, Concurso Estímulo ao Emprego Científico)
contract (2020.00275.CEECIND).
article_processing_charge: Yes
article_type: original
author:
- first_name: Katherine E.
full_name: Hearn, Katherine E.
last_name: Hearn
- first_name: Eva L.
full_name: Koch, Eva L.
last_name: Koch
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: Hearn KE, Koch EL, Stankowski S, et al. Differing associations between sex
determination and sex-linked inversions in two ecotypes of Littorina saxatilis.
Evolution Letters. 2022;6(5):358-374. doi:10.1002/evl3.295
apa: Hearn, K. E., Koch, E. L., Stankowski, S., Butlin, R. K., Faria, R., Johannesson,
K., & Westram, A. M. (2022). Differing associations between sex determination
and sex-linked inversions in two ecotypes of Littorina saxatilis. Evolution
Letters. Oxford University Press. https://doi.org/10.1002/evl3.295
chicago: Hearn, Katherine E., Eva L. Koch, Sean Stankowski, Roger K. Butlin, Rui
Faria, Kerstin Johannesson, and Anja M Westram. “Differing Associations between
Sex Determination and Sex-Linked Inversions in Two Ecotypes of Littorina Saxatilis.”
Evolution Letters. Oxford University Press, 2022. https://doi.org/10.1002/evl3.295.
ieee: K. E. Hearn et al., “Differing associations between sex determination
and sex-linked inversions in two ecotypes of Littorina saxatilis,” Evolution
Letters, vol. 6, no. 5. Oxford University Press, pp. 358–374, 2022.
ista: Hearn KE, Koch EL, Stankowski S, Butlin RK, Faria R, Johannesson K, Westram
AM. 2022. Differing associations between sex determination and sex-linked inversions
in two ecotypes of Littorina saxatilis. Evolution Letters. 6(5), 358–374.
mla: Hearn, Katherine E., et al. “Differing Associations between Sex Determination
and Sex-Linked Inversions in Two Ecotypes of Littorina Saxatilis.” Evolution
Letters, vol. 6, no. 5, Oxford University Press, 2022, pp. 358–74, doi:10.1002/evl3.295.
short: K.E. Hearn, E.L. Koch, S. Stankowski, R.K. Butlin, R. Faria, K. Johannesson,
A.M. Westram, Evolution Letters 6 (2022) 358–374.
date_created: 2022-08-28T22:02:02Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2025-06-12T06:22:56Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1002/evl3.295
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publisher: Oxford University Press
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title: Differing associations between sex determination and sex-linked inversions
in two ecotypes of Littorina saxatilis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
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year: '2022'
...
---
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abstract:
- lang: eng
text: Chromosomal inversions have been shown to play a major role in a local adaptation
by suppressing recombination between alternative arrangements and maintaining
beneficial allele combinations. However, so far, their importance relative to
the remaining genome remains largely unknown. Understanding the genetic architecture
of adaptation requires better estimates of how loci of different effect sizes
contribute to phenotypic variation. Here, we used three Swedish islands where
the marine snail Littorina saxatilis has repeatedly evolved into two distinct
ecotypes along a habitat transition. We estimated the contribution of inversion
polymorphisms to phenotypic divergence while controlling for polygenic effects
in the remaining genome using a quantitative genetics framework. We confirmed
the importance of inversions but showed that contributions of loci outside inversions
are of similar magnitude, with variable proportions dependent on the trait and
the population. Some inversions showed consistent effects across all sites, whereas
others exhibited site-specific effects, indicating that the genomic basis for
replicated phenotypic divergence is only partly shared. The contributions of sexual
dimorphism as well as environmental factors to phenotypic variation were significant
but minor compared to inversions and polygenic background. Overall, this integrated
approach provides insight into the multiple mechanisms contributing to parallel
phenotypic divergence.
acknowledgement: We thank everyone who helped with fieldwork, snail processing, and
DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo, Anne-Lise
Liabot, Irena Senčić, and Zuzanna Zagrodzka. We also thank Rui Faria and Jenny Larsson
for their contributions, with inversions and shell shape respectively. KJ was funded
by the Swedish research council Vetenskapsrådet, grant number 2017-03798. R.K.B.
and E.K. were funded by the European Research Council (ERC-2015-AdG-693030-BARRIERS).
R.K.B. was also funded by the Natural Environment Research Council and the Swedish
Research Council Vetenskapsrådet.
article_processing_charge: No
article_type: original
author:
- first_name: Eva L.
full_name: Koch, Eva L.
last_name: Koch
- first_name: Mark
full_name: Ravinet, Mark
last_name: Ravinet
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: Koch EL, Ravinet M, Westram AM, Johannesson K, Butlin RK. Genetic architecture
of repeated phenotypic divergence in Littorina saxatilis evolution. Evolution.
2022;76(10):2332-2346. doi:10.1111/evo.14602
apa: Koch, E. L., Ravinet, M., Westram, A. M., Johannesson, K., & Butlin, R.
K. (2022). Genetic architecture of repeated phenotypic divergence in Littorina
saxatilis evolution. Evolution. Wiley. https://doi.org/10.1111/evo.14602
chicago: Koch, Eva L., Mark Ravinet, Anja M Westram, Kerstin Johannesson, and Roger
K. Butlin. “Genetic Architecture of Repeated Phenotypic Divergence in Littorina
Saxatilis Evolution.” Evolution. Wiley, 2022. https://doi.org/10.1111/evo.14602.
ieee: E. L. Koch, M. Ravinet, A. M. Westram, K. Johannesson, and R. K. Butlin, “Genetic
architecture of repeated phenotypic divergence in Littorina saxatilis evolution,”
Evolution, vol. 76, no. 10. Wiley, pp. 2332–2346, 2022.
ista: Koch EL, Ravinet M, Westram AM, Johannesson K, Butlin RK. 2022. Genetic architecture
of repeated phenotypic divergence in Littorina saxatilis evolution. Evolution.
76(10), 2332–2346.
mla: Koch, Eva L., et al. “Genetic Architecture of Repeated Phenotypic Divergence
in Littorina Saxatilis Evolution.” Evolution, vol. 76, no. 10, Wiley, 2022,
pp. 2332–46, doi:10.1111/evo.14602.
short: E.L. Koch, M. Ravinet, A.M. Westram, K. Johannesson, R.K. Butlin, Evolution
76 (2022) 2332–2346.
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date_published: 2022-10-01T00:00:00Z
date_updated: 2023-08-04T09:42:11Z
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doi: 10.1111/evo.14602
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title: Genetic architecture of repeated phenotypic divergence in Littorina saxatilis
evolution
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legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
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type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
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---
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abstract:
- lang: eng
text: Reproductive isolation (RI) is a core concept in evolutionary biology. It
has been the central focus of speciation research since the modern synthesis and
is the basis by which biological species are defined. Despite this, the term is
used in seemingly different ways, and attempts to quantify RI have used very different
approaches. After showing that the field lacks a clear definition of the term,
we attempt to clarify key issues, including what RI is, how it can be quantified
in principle, and how it can be measured in practice. Following other definitions
with a genetic focus, we propose that RI is a quantitative measure of the effect
that genetic differences between populations have on gene flow. Specifically,
RI compares the flow of neutral alleles in the presence of these genetic differences
to the flow without any such differences. RI is thus greater than zero when genetic
differences between populations reduce the flow of neutral alleles between populations.
We show how RI can be quantified in a range of scenarios. A key conclusion is
that RI depends strongly on circumstances—including the spatial, temporal and
genomic context—making it difficult to compare across systems. After reviewing
methods for estimating RI from data, we conclude that it is difficult to measure
in practice. We discuss our findings in light of the goals of speciation research
and encourage the use of methods for estimating RI that integrate organismal and
genetic approaches.
acknowledgement: 'We are grateful to the participants of the ESEB satellite symposium
‘Understanding reproductive isolation: bridging conceptual barriers in speciation research’ in 2021 for the interesting discussions that helped us clarify the thoughts presented in this article. We thank Roger
Butlin, Michael Turelli and two anonymous reviewers for their thoughtful comments
on this manuscript. We are also very grateful to Roger Butlin and the Barton Group
for the continued conversa-tions about RI. In addition, we thank all participants
of the speciation survey. Part of this work was funded by the Austrian Science Fund
FWF (grant P 32166)'
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Parvathy
full_name: Surendranadh, Parvathy
id: 455235B8-F248-11E8-B48F-1D18A9856A87
last_name: Surendranadh
orcid: 0000-0001-6395-386X
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Westram AM, Stankowski S, Surendranadh P, Barton NH. What is reproductive isolation?
Journal of Evolutionary Biology. 2022;35(9):1143-1164. doi:10.1111/jeb.14005
apa: Westram, A. M., Stankowski, S., Surendranadh, P., & Barton, N. H. (2022).
What is reproductive isolation? Journal of Evolutionary Biology. Wiley.
https://doi.org/10.1111/jeb.14005
chicago: Westram, Anja M, Sean Stankowski, Parvathy Surendranadh, and Nicholas H
Barton. “What Is Reproductive Isolation?” Journal of Evolutionary Biology.
Wiley, 2022. https://doi.org/10.1111/jeb.14005.
ieee: A. M. Westram, S. Stankowski, P. Surendranadh, and N. H. Barton, “What is
reproductive isolation?,” Journal of Evolutionary Biology, vol. 35, no.
9. Wiley, pp. 1143–1164, 2022.
ista: Westram AM, Stankowski S, Surendranadh P, Barton NH. 2022. What is reproductive
isolation? Journal of Evolutionary Biology. 35(9), 1143–1164.
mla: Westram, Anja M., et al. “What Is Reproductive Isolation?” Journal of Evolutionary
Biology, vol. 35, no. 9, Wiley, 2022, pp. 1143–64, doi:10.1111/jeb.14005.
short: A.M. Westram, S. Stankowski, P. Surendranadh, N.H. Barton, Journal of Evolutionary
Biology 35 (2022) 1143–1164.
corr_author: '1'
date_created: 2023-01-16T09:59:24Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-04-15T08:20:40Z
day: '01'
ddc:
- '570'
department:
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doi: 10.1111/jeb.14005
external_id:
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pmid:
- '36063156'
file:
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date_created: 2023-01-30T10:05:31Z
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grant_number: P32166
name: Snapdragon Speciation
publication: Journal of Evolutionary Biology
publication_identifier:
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issn:
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title: What is reproductive isolation?
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---
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acknowledgement: We are very grateful to the authors of the commentaries for the interesting
discussion and to Luke Holman for handling this set of manuscripts. Part of this
work was funded by the Austrian Science Fund FWF (grant P 32166).
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Parvathy
full_name: Surendranadh, Parvathy
id: 455235B8-F248-11E8-B48F-1D18A9856A87
last_name: Surendranadh
orcid: 0000-0001-6395-386X
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Westram AM, Stankowski S, Surendranadh P, Barton NH. Reproductive isolation,
speciation, and the value of disagreement: A reply to the commentaries on ‘What
is reproductive isolation?’ Journal of Evolutionary Biology. 2022;35(9):1200-1205.
doi:10.1111/jeb.14082'
apa: 'Westram, A. M., Stankowski, S., Surendranadh, P., & Barton, N. H. (2022).
Reproductive isolation, speciation, and the value of disagreement: A reply to
the commentaries on ‘What is reproductive isolation?’ Journal of Evolutionary
Biology. Wiley. https://doi.org/10.1111/jeb.14082'
chicago: 'Westram, Anja M, Sean Stankowski, Parvathy Surendranadh, and Nicholas
H Barton. “Reproductive Isolation, Speciation, and the Value of Disagreement:
A Reply to the Commentaries on ‘What Is Reproductive Isolation?’” Journal of
Evolutionary Biology. Wiley, 2022. https://doi.org/10.1111/jeb.14082.'
ieee: 'A. M. Westram, S. Stankowski, P. Surendranadh, and N. H. Barton, “Reproductive
isolation, speciation, and the value of disagreement: A reply to the commentaries
on ‘What is reproductive isolation?,’” Journal of Evolutionary Biology,
vol. 35, no. 9. Wiley, pp. 1200–1205, 2022.'
ista: 'Westram AM, Stankowski S, Surendranadh P, Barton NH. 2022. Reproductive isolation,
speciation, and the value of disagreement: A reply to the commentaries on ‘What
is reproductive isolation?’ Journal of Evolutionary Biology. 35(9), 1200–1205.'
mla: 'Westram, Anja M., et al. “Reproductive Isolation, Speciation, and the Value
of Disagreement: A Reply to the Commentaries on ‘What Is Reproductive Isolation?’”
Journal of Evolutionary Biology, vol. 35, no. 9, Wiley, 2022, pp. 1200–05,
doi:10.1111/jeb.14082.'
short: A.M. Westram, S. Stankowski, P. Surendranadh, N.H. Barton, Journal of Evolutionary
Biology 35 (2022) 1200–1205.
corr_author: '1'
date_created: 2023-01-16T09:59:37Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2025-04-15T08:20:40Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/jeb.14082
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isi:
- '000849851100009'
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checksum: 27268009e5eec030bc10667a4ac5ed4c
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project:
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grant_number: P32166
name: Snapdragon Speciation
publication: Journal of Evolutionary Biology
publication_identifier:
eissn:
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issn:
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publisher: Wiley
quality_controlled: '1'
related_material:
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title: 'Reproductive isolation, speciation, and the value of disagreement: A reply
to the commentaries on ‘What is reproductive isolation?’'
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user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
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---
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abstract:
- lang: eng
text: Chromosomal inversions have been shown to play a major role in local adaptation
by suppressing recombination between alternative arrangements and maintaining
beneficial allele combinations. However, so far, their importance relative to
the remaining genome remains largely unknown. Understanding the genetic architecture
of adaptation requires better estimates of how loci of different effect sizes
contribute to phenotypic variation. Here, we used three Swedish islands where
the marine snail Littorina saxatilis has repeatedly evolved into two distinct
ecotypes along a habitat transition. We estimated the contribution of inversion
polymorphisms to phenotypic divergence while controlling for polygenic effects
in the remaining genome using a quantitative genetics framework. We confirmed
the importance of inversions but showed that contributions of loci outside inversions
are of similar magnitude, with variable proportions dependent on the trait and
the population. Some inversions showed consistent effects across all sites, whereas
others exhibited site-specific effects, indicating that the genomic basis for
replicated phenotypic divergence is only partly shared. The contributions of sexual
dimorphism as well as environmental factors to phenotypic variation were significant
but minor compared to inversions and polygenic background. Overall, this integrated
approach provides insight into the multiple mechanisms contributing to parallel
phenotypic divergence.
article_processing_charge: No
author:
- first_name: Eva
full_name: Koch, Eva
last_name: Koch
- first_name: Mark
full_name: Ravinet, Mark
last_name: Ravinet
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Kerstin
full_name: Jonannesson, Kerstin
last_name: Jonannesson
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: 'Koch E, Ravinet M, Westram AM, Jonannesson K, Butlin R. Data from: Genetic
architecture of repeated phenotypic divergence in Littorina saxatilis ecotype
evolution. 2022. doi:10.5061/DRYAD.M905QFV4B'
apa: 'Koch, E., Ravinet, M., Westram, A. M., Jonannesson, K., & Butlin, R. (2022).
Data from: Genetic architecture of repeated phenotypic divergence in Littorina
saxatilis ecotype evolution. Dryad. https://doi.org/10.5061/DRYAD.M905QFV4B'
chicago: 'Koch, Eva, Mark Ravinet, Anja M Westram, Kerstin Jonannesson, and Roger
Butlin. “Data from: Genetic Architecture of Repeated Phenotypic Divergence in
Littorina Saxatilis Ecotype Evolution.” Dryad, 2022. https://doi.org/10.5061/DRYAD.M905QFV4B.'
ieee: 'E. Koch, M. Ravinet, A. M. Westram, K. Jonannesson, and R. Butlin, “Data
from: Genetic architecture of repeated phenotypic divergence in Littorina saxatilis
ecotype evolution.” Dryad, 2022.'
ista: 'Koch E, Ravinet M, Westram AM, Jonannesson K, Butlin R. 2022. Data from:
Genetic architecture of repeated phenotypic divergence in Littorina saxatilis
ecotype evolution, Dryad, 10.5061/DRYAD.M905QFV4B.'
mla: 'Koch, Eva, et al. Data from: Genetic Architecture of Repeated Phenotypic
Divergence in Littorina Saxatilis Ecotype Evolution. Dryad, 2022, doi:10.5061/DRYAD.M905QFV4B.'
short: E. Koch, M. Ravinet, A.M. Westram, K. Jonannesson, R. Butlin, (2022).
date_created: 2023-05-23T16:33:12Z
date_published: 2022-07-28T00:00:00Z
date_updated: 2023-08-04T09:42:10Z
day: '28'
ddc:
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department:
- _id: NiBa
doi: 10.5061/DRYAD.M905QFV4B
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
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month: '07'
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publisher: Dryad
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year: '2022'
...
---
_id: '10926'
abstract:
- lang: eng
text: Conflict over reproduction between females and males exists because of anisogamy
and promiscuity. Together they generate differences in fitness optima between
the sexes and result in antagonistic coevolution of female and male reproductive
traits. Mounting duration is likely to be a compromise between male and female
interests whose outcome depends on the intensity of sexual selection. The timing
of sperm transfer during mounting is critical. For example, mountings may be interrupted
before sperm is transferred as a consequence of female or male choice, or they
may be prolonged to function as mate guarding. In the highly promiscuous intertidal
snail Littorina saxatilis, mountings vary substantially in duration, from less
than a minute to more than an hour, and it has been assumed that mountings of
a few minutes do not result in any sperm being transferred. Here, we examined
the timing of sperm transfer, a reproductive trait that is likely affected by
sexual conflict. We performed time-controlled mounting trials using L. saxatilis
males and virgin females, aiming to examine indirectly when the transfer of sperm
starts. We observed the relationship between mounting duration and the proportion
of developing embryos out of all eggs and embryos in the brood pouch. Developing
embryos were observed in similar proportions in all treatments (i.e. 1, 5 and
10 or more minutes at which mountings were artificially interrupted), suggesting
that sperm transfer begins rapidly (within 1 min) in L. saxatilis and very short
matings do not result in sperm shortage in the females. We discuss how the observed
pattern can be influenced by predation risk, population density, and female status
and receptivity.
article_number: eyab049
article_processing_charge: No
article_type: original
author:
- first_name: Samuel
full_name: Perini, Samuel
last_name: Perini
- first_name: Rogerk
full_name: Butlin, Rogerk
last_name: Butlin
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
citation:
ama: Perini S, Butlin R, Westram AM, Johannesson K. Very short mountings are enough
for sperm transfer in Littorina saxatilis. Journal of Molluscan Studies.
2022;88(1). doi:10.1093/mollus/eyab049
apa: Perini, S., Butlin, R., Westram, A. M., & Johannesson, K. (2022). Very
short mountings are enough for sperm transfer in Littorina saxatilis. Journal
of Molluscan Studies. Oxford University Press. https://doi.org/10.1093/mollus/eyab049
chicago: Perini, Samuel, Rogerk Butlin, Anja M Westram, and Kerstin Johannesson.
“Very Short Mountings Are Enough for Sperm Transfer in Littorina Saxatilis.” Journal
of Molluscan Studies. Oxford University Press, 2022. https://doi.org/10.1093/mollus/eyab049.
ieee: S. Perini, R. Butlin, A. M. Westram, and K. Johannesson, “Very short mountings
are enough for sperm transfer in Littorina saxatilis,” Journal of Molluscan
Studies, vol. 88, no. 1. Oxford University Press, 2022.
ista: Perini S, Butlin R, Westram AM, Johannesson K. 2022. Very short mountings
are enough for sperm transfer in Littorina saxatilis. Journal of Molluscan Studies.
88(1), eyab049.
mla: Perini, Samuel, et al. “Very Short Mountings Are Enough for Sperm Transfer
in Littorina Saxatilis.” Journal of Molluscan Studies, vol. 88, no. 1,
eyab049, Oxford University Press, 2022, doi:10.1093/mollus/eyab049.
short: S. Perini, R. Butlin, A.M. Westram, K. Johannesson, Journal of Molluscan
Studies 88 (2022).
date_created: 2022-03-27T22:01:46Z
date_published: 2022-03-01T00:00:00Z
date_updated: 2025-05-14T11:05:28Z
day: '01'
department:
- _id: BeVi
doi: 10.1093/mollus/eyab049
external_id:
isi:
- '000759081600002'
intvolume: ' 88'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprints.whiterose.ac.uk/187332/
month: '03'
oa: 1
oa_version: Submitted Version
publication: Journal of Molluscan Studies
publication_identifier:
eissn:
- 1464-3766
issn:
- 0260-1230
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Very short mountings are enough for sperm transfer in Littorina saxatilis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 88
year: '2022'
...
---
_id: '11334'
abstract:
- lang: eng
text: Hybridization is a common evolutionary process with multiple possible outcomes.
In vertebrates, interspecific hybridization has repeatedly generated parthenogenetic
hybrid species. However, it is unknown whether the generation of parthenogenetic
hybrids is a rare outcome of frequent hybridization between sexual species within
a genus or the typical outcome of rare hybridization events. Darevskia is a genus
of rock lizards with both hybrid parthenogenetic and sexual species. Using capture
sequencing, we estimate phylogenetic relationships and gene flow among the sexual
species, to determine how introgressive hybridization relates to the origins of
parthenogenetic hybrids. We find evidence for widespread hybridization with gene
flow, both between recently diverged species and deep branches. Surprisingly,
we find no signal of gene flow between parental species of the parthenogenetic
hybrids, suggesting that the parental pairs were either reproductively or geographically
isolated early in their divergence. The generation of parthenogenetic hybrids
in Darevskia is, then, a rare outcome of the total occurrence of hybridization
within the genus, but the typical outcome when specific species pairs hybridize.
Our results question the conventional view that parthenogenetic lineages are generated
by hybridization in a window of divergence. Instead, they suggest that some lineages
possess specific properties that underpin successful parthenogenetic reproduction.
acknowledgement: "The authors thank A. van der Meijden and F. Ahmadzadeh for providing
specimens and tissue samples, and A. Vardanyan, C. Corti, F. Jorge, and S. Drovetski
for support during field work. The authors also thank S. Qiu for assistance with
python scripting, S. Rocha for her support in BEAST analysis, and B. Wielstra for
his comments on\r\na previous version of the manuscript. SF was funded by FCT grant
SFRH/BD/81483/2011 (a PhD individual grant). AMW was funded by the European Union’s
Horizon 2020 research and innovation programme under Marie Skłodowska-Curie grant
agreement no. 797747. TS acknowledges funding from the Swiss National Science Foundation
(grants\r\nPP00P3_170627 and 31003A_182495). The work was carried out under financial
support of the projects “Preserving Armenian biodiversity: Joint Portuguese – Armenian
program for training in modern conservation biology” of Gulbenkian Foundation (Portugal)
and PTDC/BIABEC/101256/2008 of Fundação para a Ciência e a Tecnologia (FCT, Portugal)."
article_processing_charge: No
article_type: original
author:
- first_name: Susana
full_name: Freitas, Susana
last_name: Freitas
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Tanja
full_name: Schwander, Tanja
last_name: Schwander
- first_name: Marine
full_name: Arakelyan, Marine
last_name: Arakelyan
- first_name: Çetin
full_name: Ilgaz, Çetin
last_name: Ilgaz
- first_name: Yusuf
full_name: Kumlutas, Yusuf
last_name: Kumlutas
- first_name: David James
full_name: Harris, David James
last_name: Harris
- first_name: Miguel A.
full_name: Carretero, Miguel A.
last_name: Carretero
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: 'Freitas S, Westram AM, Schwander T, et al. Parthenogenesis in Darevskia lizards:
A rare outcome of common hybridization, not a common outcome of rare hybridization.
Evolution. 2022;76(5):899-914. doi:10.1111/evo.14462'
apa: 'Freitas, S., Westram, A. M., Schwander, T., Arakelyan, M., Ilgaz, Ç., Kumlutas,
Y., … Butlin, R. K. (2022). Parthenogenesis in Darevskia lizards: A rare outcome
of common hybridization, not a common outcome of rare hybridization. Evolution.
Wiley. https://doi.org/10.1111/evo.14462'
chicago: 'Freitas, Susana, Anja M Westram, Tanja Schwander, Marine Arakelyan, Çetin
Ilgaz, Yusuf Kumlutas, David James Harris, Miguel A. Carretero, and Roger K. Butlin.
“Parthenogenesis in Darevskia Lizards: A Rare Outcome of Common Hybridization,
Not a Common Outcome of Rare Hybridization.” Evolution. Wiley, 2022. https://doi.org/10.1111/evo.14462.'
ieee: 'S. Freitas et al., “Parthenogenesis in Darevskia lizards: A rare outcome
of common hybridization, not a common outcome of rare hybridization,” Evolution,
vol. 76, no. 5. Wiley, pp. 899–914, 2022.'
ista: 'Freitas S, Westram AM, Schwander T, Arakelyan M, Ilgaz Ç, Kumlutas Y, Harris
DJ, Carretero MA, Butlin RK. 2022. Parthenogenesis in Darevskia lizards: A rare
outcome of common hybridization, not a common outcome of rare hybridization. Evolution.
76(5), 899–914.'
mla: 'Freitas, Susana, et al. “Parthenogenesis in Darevskia Lizards: A Rare Outcome
of Common Hybridization, Not a Common Outcome of Rare Hybridization.” Evolution,
vol. 76, no. 5, Wiley, 2022, pp. 899–914, doi:10.1111/evo.14462.'
short: S. Freitas, A.M. Westram, T. Schwander, M. Arakelyan, Ç. Ilgaz, Y. Kumlutas,
D.J. Harris, M.A. Carretero, R.K. Butlin, Evolution 76 (2022) 899–914.
date_created: 2022-04-24T22:01:44Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2025-04-14T07:48:21Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
- _id: BeVi
doi: 10.1111/evo.14462
ec_funded: 1
external_id:
isi:
- '000781632500001'
pmid:
- '35323995'
file:
- access_level: open_access
checksum: c27c025ae9afcf6c804d46a909775ee5
content_type: application/pdf
creator: dernst
date_created: 2022-08-05T06:19:28Z
date_updated: 2022-08-05T06:19:28Z
file_id: '11729'
file_name: 2022_Evolution_Freitas.pdf
file_size: 2855214
relation: main_file
success: 1
file_date_updated: 2022-08-05T06:19:28Z
has_accepted_license: '1'
intvolume: ' 76'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 899-914
pmid: 1
project:
- _id: 265B41B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '797747'
name: Theoretical and empirical approaches to understanding Parallel Adaptation
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Parthenogenesis in Darevskia lizards: A rare outcome of common hybridization,
not a common outcome of rare hybridization'
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 76
year: '2022'
...
---
_id: '14984'
abstract:
- lang: eng
text: Hybrid zones are narrow geographic regions where different populations, races
or interbreeding species meet and mate, producing mixed ‘hybrid’ offspring. They
are relatively common and can be found in a diverse range of organisms and environments.
The study of hybrid zones has played an important role in our understanding of
the origin of species, with hybrid zones having been described as ‘natural laboratories’.
This is because they allow us to study,in situ, the conditions and evolutionary
forces that enable divergent taxa to remain distinct despite some ongoing gene
exchange between them.
article_processing_charge: No
author:
- first_name: Sean
full_name: Stankowski, Sean
id: 43161670-5719-11EA-8025-FABC3DDC885E
last_name: Stankowski
- first_name: Daria
full_name: Shipilina, Daria
id: 428A94B0-F248-11E8-B48F-1D18A9856A87
last_name: Shipilina
orcid: 0000-0002-1145-9226
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
citation:
ama: 'Stankowski S, Shipilina D, Westram AM. Hybrid Zones. In: Encyclopedia of
Life Sciences. Vol 2. eLS. Wiley; 2021. doi:10.1002/9780470015902.a0029355'
apa: Stankowski, S., Shipilina, D., & Westram, A. M. (2021). Hybrid Zones. In
Encyclopedia of Life Sciences (Vol. 2). Wiley. https://doi.org/10.1002/9780470015902.a0029355
chicago: Stankowski, Sean, Daria Shipilina, and Anja M Westram. “Hybrid Zones.”
In Encyclopedia of Life Sciences, Vol. 2. ELS. Wiley, 2021. https://doi.org/10.1002/9780470015902.a0029355.
ieee: S. Stankowski, D. Shipilina, and A. M. Westram, “Hybrid Zones,” in Encyclopedia
of Life Sciences, vol. 2, Wiley, 2021.
ista: 'Stankowski S, Shipilina D, Westram AM. 2021.Hybrid Zones. In: Encyclopedia
of Life Sciences. vol. 2.'
mla: Stankowski, Sean, et al. “Hybrid Zones.” Encyclopedia of Life Sciences,
vol. 2, Wiley, 2021, doi:10.1002/9780470015902.a0029355.
short: S. Stankowski, D. Shipilina, A.M. Westram, in:, Encyclopedia of Life Sciences,
Wiley, 2021.
corr_author: '1'
date_created: 2024-02-14T12:05:50Z
date_published: 2021-05-28T00:00:00Z
date_updated: 2024-10-09T21:08:11Z
day: '28'
department:
- _id: NiBa
doi: 10.1002/9780470015902.a0029355
intvolume: ' 2'
language:
- iso: eng
month: '05'
oa_version: None
publication: Encyclopedia of Life Sciences
publication_identifier:
eisbn:
- '9780470015902'
isbn:
- '9780470016176'
publication_status: published
publisher: Wiley
quality_controlled: '1'
series_title: eLS
status: public
title: Hybrid Zones
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2021'
...