---
OA_place: repository
OA_type: green
_id: '21290'
abstract:
- lang: eng
text: Gene duplication underlies evolutionary innovation, yet many paralogues remain
highly similar, raising questions about their functional divergence and physiological
relevance. The spliceosomal Sm core protein SNRPB and its mammalian-specific paralogue
SNRPN share over 90% sequence identity, but their distinct expression patterns
- SNRPB being ubiquitous and SNRPN confined to the brain - suggest specialized
functions. Why mammals have two different spliceosomes has remained obscure. Here,
we generated isogenic human cell lines expressing ectopically either SNRPB or
SNRPN exclusively and found that SNRPN stabilizes transcripts involved in energy
metabolism and mitochondrial function, leading to increased mitochondrial abundance
and oxygen consumption. Despite similar spliceosomal interactomes, SNRPN more
strongly associates with the PRMT5 methylosome complex and exhibits dynamic arginine
methylation in its C-terminal region that is sensitive to translation inhibition
and amino acid availability. The SNRPN-dependent transcriptome responds to translation
inhibition by stabilizing long, intron-rich genes involved in amino acid and energy
metabolism. Our findings reveal a nutrient-sensitive, methylation-dependent mechanism
that differentiates the two paralogues. This suggests that SNRPN functions as
a metabolic-specialized spliceosomal subunit thereby providing tissue-specific
adaptation of RNA processing in mammals.
acknowledgement: "We thank Oliver Mühlemann and Alex Hofer (University of Bern) for
sharing SMG inhibitors\r\nand for their expertise in nonsense-mediated mRNA decay
and Maria Hondele for critical\r\nreading of the manuscript draft. We also thank
the IMB Genomics Core Facility for assistance\r\nwith library preparation and sequencing,
Martin Möckel and the IMB Protein Production Core\r\nFacility for providing enzymes
used in this work, Marton Gelleri together with the IMB\r\nMicroscopy Core Facility
for support with microscopy and FRAP experiments, Jasmin Cartano\r\nfor proteomics
sample processing and the IMB Flow Cytometry Core Facility for support. In\r\naddition,
we thank the Imaging Core Facility (IMCF) and the FACS Core Facility at the\r\nBiozentrum,
University of Basel, for technical assistance. CIKV acknowledges funding by the\r\nDeutsche
Forschungsgemeinschaft (DFG, German Research Foundation) - Individual Grant\r\nProject
no. 513744403, Scientific Network Grant Project no. 531902894, GRK2526 “Genevo”\r\n-
Project no. 407023052”, GRK2859 (“4R”) - Project no. 491145305, Forschungsinitiative\r\nRheinland-Pfalz
(ReALity), the EMBO Young Investigator Program (5795), institutional\r\nfunding
from the Institute of Molecular Biology and funds from the Kanton Basel-Stadt and\r\nBasel-Land
provided to the Biozentrum of the University Basel. J.H.G.F.G. was part of the\r\n‘Science
of Healthy Ageing Research Programme’ (SHARP) initiative funded by RhinelandPalatinate’s
Ministry of Science, Education and Culture. PR is funded by the Biozentrum PhD\r\nFellowships
Program. MFB received financial support from the intramural High Potentials\r\nGrant
program of the University Medical Center Mainz, Forschungsinitiative Rheinland-Pfalz\r\n(ReALity)
and Stiftungen zugunsten der Medizinischen Fakultät der LMU Klinikum (26069).\r\nInstruments
in the IMB core facilities were supported by funds from the DFG: Laser Scanning\r\nConfocal
(Leica Stellaris 8 Falcon, funded by the DFG - Project #497669232), Orbitrap Astral
system (funded by the DFG - Project #524805621) and BD LSRFortessa SOPR is funded
by\r\nthe DFG - Project #210253511.\r\n"
article_processing_charge: No
author:
- first_name: Feyza
full_name: Polat Haas, Feyza
last_name: Polat Haas
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: Polina
full_name: Rusina, Polina
last_name: Rusina
- first_name: Anusha
full_name: Gopalan, Anusha
last_name: Gopalan
- first_name: Hector
full_name: Fritz, Hector
last_name: Fritz
- first_name: Azamat
full_name: Akhmetkaliyev, Azamat
last_name: Akhmetkaliyev
- first_name: Frank
full_name: Ruehle, Frank
last_name: Ruehle
- first_name: Anna
full_name: Einsiedel, Anna
last_name: Einsiedel
- first_name: Anna
full_name: Szczepinska, Anna
last_name: Szczepinska
- first_name: Fridolin
full_name: Kielisch, Fridolin
last_name: Kielisch
- first_name: Jia-Xuan
full_name: Chen, Jia-Xuan
last_name: Chen
- first_name: Susanne
full_name: Nguyen, Susanne
last_name: Nguyen
- first_name: Thierry
full_name: Schmidlin, Thierry
last_name: Schmidlin
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: M. Felicia
full_name: Bailicata, M. Felicia
last_name: Bailicata
- first_name: Claudia Isabelle
full_name: Keller Valsecchi, Claudia Isabelle
last_name: Keller Valsecchi
citation:
ama: Polat Haas F, Villalba Requena A, Rusina P, et al. The splicing paralogues
SNRPB and SNRPN control differential metabolic states. bioRxiv. doi:10.64898/2026.02.11.705284
apa: Polat Haas, F., Villalba Requena, A., Rusina, P., Gopalan, A., Fritz, H., Akhmetkaliyev,
A., … Keller Valsecchi, C. I. (n.d.). The splicing paralogues SNRPB and SNRPN
control differential metabolic states. bioRxiv. https://doi.org/10.64898/2026.02.11.705284
chicago: Polat Haas, Feyza, Ana Villalba Requena, Polina Rusina, Anusha Gopalan,
Hector Fritz, Azamat Akhmetkaliyev, Frank Ruehle, et al. “The Splicing Paralogues
SNRPB and SNRPN Control Differential Metabolic States.” BioRxiv, n.d. https://doi.org/10.64898/2026.02.11.705284.
ieee: F. Polat Haas et al., “The splicing paralogues SNRPB and SNRPN control
differential metabolic states.,” bioRxiv. .
ista: Polat Haas F, Villalba Requena A, Rusina P, Gopalan A, Fritz H, Akhmetkaliyev
A, Ruehle F, Einsiedel A, Szczepinska A, Kielisch F, Chen J-X, Nguyen S, Schmidlin
T, Hippenmeyer S, Bailicata MF, Keller Valsecchi CI. The splicing paralogues SNRPB
and SNRPN control differential metabolic states. bioRxiv, 10.64898/2026.02.11.705284.
mla: Polat Haas, Feyza, et al. “The Splicing Paralogues SNRPB and SNRPN Control
Differential Metabolic States.” BioRxiv, doi:10.64898/2026.02.11.705284.
short: F. Polat Haas, A. Villalba Requena, P. Rusina, A. Gopalan, H. Fritz, A. Akhmetkaliyev,
F. Ruehle, A. Einsiedel, A. Szczepinska, F. Kielisch, J.-X. Chen, S. Nguyen, T.
Schmidlin, S. Hippenmeyer, M.F. Bailicata, C.I. Keller Valsecchi, BioRxiv (n.d.).
date_created: 2026-02-17T11:35:59Z
date_published: 2026-02-11T00:00:00Z
date_updated: 2026-02-23T11:03:33Z
day: '11'
department:
- _id: SiHi
doi: 10.64898/2026.02.11.705284
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.64898/2026.02.11.705284
month: '02'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: submitted
status: public
title: The splicing paralogues SNRPB and SNRPN control differential metabolic states.
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '19717'
abstract:
- lang: eng
text: Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the
cerebral cortex through incompletely understood processes. Herein, we combine
Mosaic Analysis with Double Markers (MADM)-based clonal analysis at embryonic
days 12.5 and 13.5 with early postnatal callosal tracing to reveal a lineage progression
that challenges the inside-outside model of cortical development and the conventional
view of an invariable sequence of asymmetric neurogenic divisions. Our data demonstrate
that early multipotent RGPs generate all extra-telencephalic (ET) and intra-telencephalic
(IT) PNs across all layers through parallel sublineages and the random specification,
during the earliest neurogenic divisions, of fate-restricted daughter RGPs. While
the neuronal production of the parental multipotent RGPs consists of small ET-PN
or IT-PN outputs, fate-restricted RGPs produce larger translaminar outputs spanning
deep and upper layers of only IT-PNs, the predominant mammalian PN subtype. We
further show that the emergence of IT-PN fate-restricted RGPs also leads to quantitatively
and temporally stereotyped neurogenesis population-wise.
acknowledgement: "We thank M. Caouyette for the plasmid construction for Pou3f1 overexpression;
C. Varela747 Martínez for help with the code for graphical analysis; all members
from the Nieto’s lab for\r\ncomment on the manuscript, specially to F. Martín for
the insightful discussions;J.C. Oliveros\r\nand J.A. García from the computational
service of the CNB for help with the analysis of\r\nRNAseq dataset, C.O. Sorzano
for the help with statistical analysis, and the service of\r\nAdvance Optical Microscopy
of the CNB for their technical advice.\r\nI.V.M holds a fellowship funded by MCICIU
(PRE-2018-083376), the work was funded by\r\nPID2020-112831GB-I00 funded by MCIN/AEI
/10.13039/501100011033.\r\n"
article_processing_charge: No
author:
- first_name: I
full_name: Varela-Martínez, I
last_name: Varela-Martínez
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: J.
full_name: Garcia-Marqués, J.
last_name: Garcia-Marqués
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: M.
full_name: Nieto, M.
last_name: Nieto
citation:
ama: Varela-Martínez I, Villalba Requena A, Garcia-Marqués J, Hippenmeyer S, Nieto
M. Early emergence of projection-subtype fate-restricted radial glial progenitors
orchestrates neocortical neurogenesis. bioRxiv. 2025. doi:10.1101/2025.05.07.652665
apa: Varela-Martínez, I., Villalba Requena, A., Garcia-Marqués, J., Hippenmeyer,
S., & Nieto, M. (2025). Early emergence of projection-subtype fate-restricted
radial glial progenitors orchestrates neocortical neurogenesis. bioRxiv.
https://doi.org/10.1101/2025.05.07.652665
chicago: Varela-Martínez, I, Ana Villalba Requena, J. Garcia-Marqués, Simon Hippenmeyer,
and M. Nieto. “Early Emergence of Projection-Subtype Fate-Restricted Radial Glial
Progenitors Orchestrates Neocortical Neurogenesis.” BioRxiv, 2025. https://doi.org/10.1101/2025.05.07.652665.
ieee: I. Varela-Martínez, A. Villalba Requena, J. Garcia-Marqués, S. Hippenmeyer,
and M. Nieto, “Early emergence of projection-subtype fate-restricted radial glial
progenitors orchestrates neocortical neurogenesis,” bioRxiv. 2025.
ista: Varela-Martínez I, Villalba Requena A, Garcia-Marqués J, Hippenmeyer S, Nieto
M. 2025. Early emergence of projection-subtype fate-restricted radial glial progenitors
orchestrates neocortical neurogenesis. bioRxiv, 10.1101/2025.05.07.652665.
mla: Varela-Martínez, I., et al. “Early Emergence of Projection-Subtype Fate-Restricted
Radial Glial Progenitors Orchestrates Neocortical Neurogenesis.” BioRxiv,
2025, doi:10.1101/2025.05.07.652665.
short: I. Varela-Martínez, A. Villalba Requena, J. Garcia-Marqués, S. Hippenmeyer,
M. Nieto, BioRxiv (2025).
date_created: 2025-05-20T10:19:29Z
date_published: 2025-05-07T00:00:00Z
date_updated: 2025-05-28T06:37:46Z
day: '07'
department:
- _id: SiHi
doi: 10.1101/2025.05.07.652665
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2025.05.07.652665
month: '05'
oa: 1
oa_version: Preprint
publication: bioRxiv
publication_status: published
status: public
title: Early emergence of projection-subtype fate-restricted radial glial progenitors
orchestrates neocortical neurogenesis
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '19718'
abstract:
- lang: eng
text: The cerebral cortex is arguably the most complex organ in humans. The cortical
architecture is characterized by a remarkable diversity of neuronal and glial
cell types that make up its neuronal circuits. Following a precise temporally
ordered program, radial glia progenitor (RGP) cells generate all cortical excitatory
projection neurons and glial cell-types. Cortical excitatory projection neurons
are produced either directly or via intermediate progenitors, through indirect
neurogenesis. How the extensive cortical cell-type diversity is generated during
cortex development remains, however, a fundamental open question. How do RGPs
quantitatively and qualitatively generate all the neocortical neurons? How does
direct and indirect neurogenesis contribute to the establishment of neuronal and
lineage heterogeneity? Whether RGPs represent a homogeneous and/or multipotent
progenitor population, or if RGPs consist of heterogeneous groups is currently
also not known. In this review, we will summarize the latest findings that contributed
to a deeper insight into the above key questions.
acknowledgement: We wish to thank all members of the Hippenmeyer laboratory at ISTA
for exciting discussions on the subject of this review. We apologize to colleagues
whose work we could not cite and/or discuss in the frame of the available space.
Work in the Hippenmeyer laboratory on the discussed topic is supported by ISTA institutional
funds, an EMBO LTF (ALTF 994–2023) to F.P, and FWF SFB F78 to S.H.
article_number: '103046'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Fabrizia
full_name: Pipicelli, Fabrizia
id: 649134fd-d012-11ed-8f82-db1e5050f9ba
last_name: Pipicelli
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Pipicelli F, Villalba Requena A, Hippenmeyer S. How radial glia progenitor
lineages generate cell-type diversity in the developing cerebral cortex. Current
Opinion in Neurobiology. 2025;93. doi:10.1016/j.conb.2025.103046
apa: Pipicelli, F., Villalba Requena, A., & Hippenmeyer, S. (2025). How radial
glia progenitor lineages generate cell-type diversity in the developing cerebral
cortex. Current Opinion in Neurobiology. Elsevier. https://doi.org/10.1016/j.conb.2025.103046
chicago: Pipicelli, Fabrizia, Ana Villalba Requena, and Simon Hippenmeyer. “How
Radial Glia Progenitor Lineages Generate Cell-Type Diversity in the Developing
Cerebral Cortex.” Current Opinion in Neurobiology. Elsevier, 2025. https://doi.org/10.1016/j.conb.2025.103046.
ieee: F. Pipicelli, A. Villalba Requena, and S. Hippenmeyer, “How radial glia progenitor
lineages generate cell-type diversity in the developing cerebral cortex,” Current
Opinion in Neurobiology, vol. 93. Elsevier, 2025.
ista: Pipicelli F, Villalba Requena A, Hippenmeyer S. 2025. How radial glia progenitor
lineages generate cell-type diversity in the developing cerebral cortex. Current
Opinion in Neurobiology. 93, 103046.
mla: Pipicelli, Fabrizia, et al. “How Radial Glia Progenitor Lineages Generate Cell-Type
Diversity in the Developing Cerebral Cortex.” Current Opinion in Neurobiology,
vol. 93, 103046, Elsevier, 2025, doi:10.1016/j.conb.2025.103046.
short: F. Pipicelli, A. Villalba Requena, S. Hippenmeyer, Current Opinion in Neurobiology
93 (2025).
corr_author: '1'
date_created: 2025-05-20T10:20:09Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-12-30T10:54:14Z
day: '01'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.conb.2025.103046
external_id:
isi:
- '001496227000001'
pmid:
- '40383049'
file:
- access_level: open_access
checksum: 05bacb4acbe6275d43e873dec9ba1d52
content_type: application/pdf
creator: dernst
date_created: 2025-12-30T08:25:49Z
date_updated: 2025-12-30T08:25:49Z
file_id: '20894'
file_name: 2025_CurrentOpNeurobiology_Pipicelli.pdf
file_size: 1592649
relation: main_file
success: 1
file_date_updated: 2025-12-30T08:25:49Z
has_accepted_license: '1'
intvolume: ' 93'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
grant_number: F7805
name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
Mechanisms of Neural Stem Cell Lineage Progression
- _id: 7c084566-9f16-11ee-852c-c88a1dbbf1cf
grant_number: ALTF 994-2023
name: Role of cell lineage in generating cell-type diversity in developing neocortex’
publication: Current Opinion in Neurobiology
publication_identifier:
issn:
- 0959-4388
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: How radial glia progenitor lineages generate cell-type diversity in the developing
cerebral cortex
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 93
year: '2025'
...
---
OA_place: publisher
OA_type: free access
_id: '12542'
abstract:
- lang: eng
text: In this issue of Neuron, Espinosa-Medina et al.1 present the TEMPO (Temporal
Encoding and Manipulation in a Predefined Order) system, which enables the marking
and genetic manipulation of sequentially generated cell lineages in vertebrate
species in vivo.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Villalba Requena A, Hippenmeyer S. Going back in time with TEMPO. Neuron.
2023;111(3):291-293. doi:10.1016/j.neuron.2023.01.006
apa: Villalba Requena, A., & Hippenmeyer, S. (2023). Going back in time with
TEMPO. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2023.01.006
chicago: Villalba Requena, Ana, and Simon Hippenmeyer. “Going Back in Time with
TEMPO.” Neuron. Elsevier, 2023. https://doi.org/10.1016/j.neuron.2023.01.006.
ieee: A. Villalba Requena and S. Hippenmeyer, “Going back in time with TEMPO,” Neuron,
vol. 111, no. 3. Elsevier, pp. 291–293, 2023.
ista: Villalba Requena A, Hippenmeyer S. 2023. Going back in time with TEMPO. Neuron.
111(3), 291–293.
mla: Villalba Requena, Ana, and Simon Hippenmeyer. “Going Back in Time with TEMPO.”
Neuron, vol. 111, no. 3, Elsevier, 2023, pp. 291–93, doi:10.1016/j.neuron.2023.01.006.
short: A. Villalba Requena, S. Hippenmeyer, Neuron 111 (2023) 291–293.
corr_author: '1'
date_created: 2023-02-12T23:00:58Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2025-06-25T06:24:25Z
day: '01'
department:
- _id: SiHi
doi: 10.1016/j.neuron.2023.01.006
external_id:
isi:
- '000994473300001'
pmid:
- '36731425'
intvolume: ' 111'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.neuron.2023.01.006
month: '02'
oa: 1
oa_version: Published Version
page: 291-293
pmid: 1
publication: Neuron
publication_identifier:
eissn:
- 1097-4199
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Going back in time with TEMPO
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 111
year: '2023'
...
---
_id: '14757'
abstract:
- lang: eng
text: The cerebral cortex is comprised of a vast cell-type diversity sequentially
generated by cortical progenitor cells. Faithful progenitor lineage progression
requires the tight orchestration of distinct molecular and cellular mechanisms
regulating proper progenitor proliferation behavior and differentiation. Correct
execution of developmental programs involves a complex interplay of cell intrinsic
and tissue-wide mechanisms. Many studies over the past decades have been able
to determine a plethora of genes critically involved in cortical development.
However, only a few made use of genetic paradigms with sparse and global gene
deletion to probe cell-autonomous vs. tissue-wide contribution. In this chapter,
we will elaborate on the importance of dissecting the cell-autonomous and tissue-wide
mechanisms to gain a precise understanding of gene function during radial glial
progenitor lineage progression.
article_processing_charge: No
author:
- first_name: Ana
full_name: Villalba Requena, Ana
id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
last_name: Villalba Requena
orcid: 0000-0002-5615-5277
- first_name: Nicole
full_name: Amberg, Nicole
id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
last_name: Amberg
orcid: 0000-0002-3183-8207
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: 'Villalba Requena A, Amberg N, Hippenmeyer S. Interplay of Cell‐autonomous
Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage
Progression. In: Huttner W, ed. Neocortical Neurogenesis in Development and
Evolution. Wiley; 2023:169-191. doi:10.1002/9781119860914.ch10'
apa: Villalba Requena, A., Amberg, N., & Hippenmeyer, S. (2023). Interplay of
Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial
Progenitor Lineage Progression. In W. Huttner (Ed.), Neocortical Neurogenesis
in Development and Evolution (pp. 169–191). Wiley. https://doi.org/10.1002/9781119860914.ch10
chicago: Villalba Requena, Ana, Nicole Amberg, and Simon Hippenmeyer. “Interplay
of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating Radial
Glial Progenitor Lineage Progression.” In Neocortical Neurogenesis in Development
and Evolution, edited by Wieland Huttner, 169–91. Wiley, 2023. https://doi.org/10.1002/9781119860914.ch10.
ieee: A. Villalba Requena, N. Amberg, and S. Hippenmeyer, “Interplay of Cell‐autonomous
Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage
Progression,” in Neocortical Neurogenesis in Development and Evolution,
W. Huttner, Ed. Wiley, 2023, pp. 169–191.
ista: 'Villalba Requena A, Amberg N, Hippenmeyer S. 2023.Interplay of Cell‐autonomous
Gene Function and Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage
Progression. In: Neocortical Neurogenesis in Development and Evolution. , 169–191.'
mla: Villalba Requena, Ana, et al. “Interplay of Cell‐autonomous Gene Function and
Tissue‐wide Mechanisms Regulating Radial Glial Progenitor Lineage Progression.”
Neocortical Neurogenesis in Development and Evolution, edited by Wieland
Huttner, Wiley, 2023, pp. 169–91, doi:10.1002/9781119860914.ch10.
short: A. Villalba Requena, N. Amberg, S. Hippenmeyer, in:, W. Huttner (Ed.), Neocortical
Neurogenesis in Development and Evolution, Wiley, 2023, pp. 169–191.
corr_author: '1'
date_created: 2024-01-08T13:16:36Z
date_published: 2023-08-08T00:00:00Z
date_updated: 2024-10-09T21:07:46Z
day: '08'
department:
- _id: SiHi
doi: 10.1002/9781119860914.ch10
editor:
- first_name: Wieland
full_name: Huttner, Wieland
last_name: Huttner
language:
- iso: eng
month: '08'
oa_version: None
page: 169-191
publication: Neocortical Neurogenesis in Development and Evolution
publication_identifier:
eisbn:
- '9781119860914'
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interplay of Cell‐autonomous Gene Function and Tissue‐wide Mechanisms Regulating
Radial Glial Progenitor Lineage Progression
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...