@phdthesis{12531,
  abstract     = {All visual experiences of the vertebrates begin with light being converted into electrical signals
by the eye retina. Retinal ganglion cells (RGCs) are the neurons of the innermost layer of the
mammal retina, and they transmit visual information to the rest of the brain.
It has been shown that RGCs vary in their morphology and genetic profiles, moreover they can
be unambiguously grouped into subtypes that share the same morphological and/or molecular
properties. However, in terms of RGCs function, it remains unclear how many distinct types
there are and what response properties their typology relies on. Even given the recent studies
that successfully classified RGCs in a patch of the retina [1] and in scotopic conditions [2], the
question remains whether the found subtypes persist across the entire retina.
In this work, using a novel imaging method, we show that, when sampled from a large portion
of the retina, RGCs can not be clearly divided into functional subtypes. We found that in
photopic conditions, which implies more prominent natural scene statistic differences across
the visual field, response properties can be exhibited by cells differently depending on their
location in the retina, which leads to formation of a gradient of features rather than distinct
classes.
This finding suggests that RGCs follow a global organization across the visual field of the
animal, adapting each RGC subtype to the requirements imposed by the natural scene statistics.},
  author       = {Kirillova, Kseniia},
  issn         = {2791-4585},
  pages        = {46},
  publisher    = {Institute of Science and Technology Austria},
  title        = {{Panoramic functional gradients across the mouse retina}},
  doi          = {10.15479/at:ista:12531},
  year         = {2023},
}