[{"language":[{"iso":"eng"}],"pmid":1,"year":"2025","date_published":"2025-05-15T00:00:00Z","oa":1,"article_processing_charge":"Yes (in subscription journal)","oa_version":"Published Version","file_date_updated":"2025-08-05T12:07:24Z","has_accepted_license":"1","day":"15","article_type":"original","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Journal of Colloid and Interface Science","scopus_import":"1","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","quality_controlled":"1","citation":{"mla":"Scacchi, Alberto, et al. “A Coarse-Grained Model for Aqueous Two-Phase Systems: Application to Ferrofluids.” <i>Journal of Colloid and Interface Science</i>, vol. 686, Elsevier, 2025, pp. 1135–46, doi:<a href=\"https://doi.org/10.1016/j.jcis.2025.01.256\">10.1016/j.jcis.2025.01.256</a>.","ama":"Scacchi A, Rigoni C, Haataja M, Timonen JVI, Sammalkorpi M. A coarse-grained model for aqueous two-phase systems: Application to ferrofluids. <i>Journal of Colloid and Interface Science</i>. 2025;686:1135-1146. doi:<a href=\"https://doi.org/10.1016/j.jcis.2025.01.256\">10.1016/j.jcis.2025.01.256</a>","ista":"Scacchi A, Rigoni C, Haataja M, Timonen JVI, Sammalkorpi M. 2025. A coarse-grained model for aqueous two-phase systems: Application to ferrofluids. Journal of Colloid and Interface Science. 686, 1135–1146.","apa":"Scacchi, A., Rigoni, C., Haataja, M., Timonen, J. V. I., &#38; Sammalkorpi, M. (2025). A coarse-grained model for aqueous two-phase systems: Application to ferrofluids. <i>Journal of Colloid and Interface Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jcis.2025.01.256\">https://doi.org/10.1016/j.jcis.2025.01.256</a>","short":"A. Scacchi, C. Rigoni, M. Haataja, J.V.I. Timonen, M. Sammalkorpi, Journal of Colloid and Interface Science 686 (2025) 1135–1146.","ieee":"A. Scacchi, C. Rigoni, M. Haataja, J. V. I. Timonen, and M. Sammalkorpi, “A coarse-grained model for aqueous two-phase systems: Application to ferrofluids,” <i>Journal of Colloid and Interface Science</i>, vol. 686. Elsevier, pp. 1135–1146, 2025.","chicago":"Scacchi, Alberto, Carlo Rigoni, Mikko Haataja, Jaakko V.I. Timonen, and Maria Sammalkorpi. “A Coarse-Grained Model for Aqueous Two-Phase Systems: Application to Ferrofluids.” <i>Journal of Colloid and Interface Science</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.jcis.2025.01.256\">https://doi.org/10.1016/j.jcis.2025.01.256</a>."},"_id":"19024","department":[{"_id":"RaKl"}],"date_updated":"2025-09-30T10:31:45Z","intvolume":"       686","OA_type":"hybrid","date_created":"2025-02-16T23:02:33Z","author":[{"first_name":"Alberto","full_name":"Scacchi, Alberto","last_name":"Scacchi"},{"first_name":"Carlo","id":"c5df3b62-5f9e-11ef-ba3c-b97f5b5b5ef0","full_name":"Rigoni, Carlo","last_name":"Rigoni"},{"full_name":"Haataja, Mikko","first_name":"Mikko","last_name":"Haataja"},{"last_name":"Timonen","full_name":"Timonen, Jaakko V.I.","first_name":"Jaakko V.I."},{"last_name":"Sammalkorpi","first_name":"Maria","full_name":"Sammalkorpi, Maria"}],"publisher":"Elsevier","page":"1135-1146","acknowledgement":"This work was supported by the Swiss National Science Foundation under the project no. P500PT_206916 (A.S.) and the Academy of Finland through its Centres of Excellence Programs (2022-2029, LIBER) under projects no. 346111 and 364205 (M.S.) and 346112 and 364206 (J.T.). MPH was supported by the National Science Foundation through the Princeton University (PCCM) Materials Research Science and Engineering Center DMR-2011750. A.S. warmly thanks Bob Evans for extensive scientific discussions and for his hospitality during the research visit in Bristol. Computational resources by CSC IT Centre for Finland, the Aalto Science-IT project, and RAMI – RawMatters Finland Infrastructure are also gratefully acknowledged.","doi":"10.1016/j.jcis.2025.01.256","isi":1,"OA_place":"publisher","publication_status":"published","external_id":{"pmid":["39933351"],"arxiv":["2311.16906"],"isi":["001426125300001"]},"arxiv":1,"ddc":["540"],"related_material":{"record":[{"id":"19033","status":"public","relation":"research_data"}]},"publication_identifier":{"issn":["0021-9797"],"issnl":["0021-9797"],"eissn":["1095-7103"]},"title":"A coarse-grained model for aqueous two-phase systems: Application to ferrofluids","PlanS_conform":"1","month":"05","fulldoi":"https://doi.org/10.1016/j.jcis.2025.01.256","type":"journal_article","volume":686,"abstract":[{"text":"Aqueous two-phase systems (ATPSs), phase-separating solutions of water soluble but mutually immiscible molecular species, offer fascinating prospects for selective partitioning, purification, and extraction. Here, we formulate a general Brownian dynamics based coarse-grained simulation model for an ATPS of two water soluble but mutually immiscible polymer species. Including additional solute species into the model is straightforward, which enables capturing the assembly and partitioning response of, e.g., nanoparticles (NPs), additional macromolecular species, or impurities in the ATPS. We demonstrate that the simulation model captures satisfactorily the phase separation, partitioning, and interfacial properties of an actual ATPS using a model ATPS in which a polymer mixture of dextran and polyethylene glycol (PEG) phase separates, and magnetic NPs selectively partition into one of the two polymeric phases. Phase separation and NP partitioning are characterized both via the computational model and experimentally, under different conditions. The simulation model captures the trends observed in the experimental system and quantitatively links the partitioning behavior to the component species interactions. Finally, the simulation model reveals that the ATPS interface fluctuations in systems with magnetic NPs as a partitioned species can be controlled by the magnetic field at length scales much smaller than those probed experimentally to date.","lang":"eng"}],"file":[{"file_name":"2025_JourColloidScie_Scacchi.pdf","relation":"main_file","access_level":"open_access","date_created":"2025-08-05T12:07:24Z","success":1,"date_updated":"2025-08-05T12:07:24Z","content_type":"application/pdf","file_size":4212615,"file_id":"20128","checksum":"a52b72a243a717d85c348f53898ad934","creator":"dernst"}]},{"title":"Protein cage directed assembly of binary nanoparticle superlattices","month":"12","publication_identifier":{"eissn":["2198-3844"]},"DOAJ_listed":"1","ddc":["540"],"file":[{"access_level":"open_access","content_type":"application/pdf","date_updated":"2025-01-13T09:16:25Z","success":1,"date_created":"2025-01-13T09:16:25Z","file_name":"2024_AdvancedScience_Zhou.pdf","relation":"main_file","creator":"dernst","file_size":7040083,"file_id":"18834","checksum":"00451eeb2c9eecf1ff41ad243c793a51"}],"type":"journal_article","fulldoi":"https://doi.org/10.1002/advs.202408416","abstract":[{"lang":"eng","text":"Inorganic nanoparticles can be assembled into superlattices with unique optical and magnetic properties arising from collective behavior. Protein cages can be utilized to guide this assembly by encapsulating nanoparticles and promoting their assembly into ordered structures. However, creating ordered multi-component structures with different protein cage types and sizes remains a challenge. Here, the co-crystallization of two different protein cages (cowpea chlorotic mottle virus and ferritin) characterized by opposing surface charges and unequal diameter is shown. Precise tuning of the electrostatic attraction between the cages enabled the preparation of binary crystals with dimensions up to several tens of micrometers. Additionally, binary metal nanoparticle superlattices are achieved by loading gold and iron oxide nanoparticles inside the cavities of the protein cages. The resulting structure adopts an AB2FCC configuration that also impacts the dipolar coupling between the particles and hence the optical properties of the crystals, providing key insight for the future preparation of plasmonic and magnetic nanoparticle metamaterials."}],"volume":11,"doi":"10.1002/advs.202408416","acknowledgement":"This work has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (Grant Agreement No. 101002258). The authors acknowledge the provision of facilities and technical support by Aalto University Bioeconomy Facilities and OtaNanoNanomicroscopy Center (Aalto-NMC). This work was carried out under the Academy of Finland's Centers of Excellence Programme, Life Inspired Hybrid Materials (LIBER) Center of Excellence (2022–2029), project number 346110 and 346112.","publisher":"Wiley","date_updated":"2025-09-08T14:20:31Z","department":[{"_id":"RaKl"}],"intvolume":"        11","author":[{"last_name":"Zhou","full_name":"Zhou, Yu","first_name":"Yu"},{"full_name":"Shaukat, Ahmed","first_name":"Ahmed","last_name":"Shaukat"},{"full_name":"Seitsonen, Jani","first_name":"Jani","last_name":"Seitsonen"},{"last_name":"Rigoni","full_name":"Rigoni, Carlo","first_name":"Carlo","id":"c5df3b62-5f9e-11ef-ba3c-b97f5b5b5ef0"},{"full_name":"Timonen, Jaakko V.I.","first_name":"Jaakko V.I.","last_name":"Timonen"},{"first_name":"Mauri A.","full_name":"Kostiainen, Mauri A.","last_name":"Kostiainen"}],"OA_type":"gold","date_created":"2024-10-20T22:02:07Z","issue":"45","external_id":{"isi":["001330745600001"],"pmid":["39401426"]},"publication_status":"published","isi":1,"OA_place":"publisher","day":"04","publication":"Advanced Science","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_type":"original","has_accepted_license":"1","article_number":"2408416","citation":{"ista":"Zhou Y, Shaukat A, Seitsonen J, Rigoni C, Timonen JVI, Kostiainen MA. 2024. Protein cage directed assembly of binary nanoparticle superlattices. Advanced Science. 11(45), 2408416.","apa":"Zhou, Y., Shaukat, A., Seitsonen, J., Rigoni, C., Timonen, J. V. I., &#38; Kostiainen, M. A. (2024). Protein cage directed assembly of binary nanoparticle superlattices. <i>Advanced Science</i>. Wiley. <a href=\"https://doi.org/10.1002/advs.202408416\">https://doi.org/10.1002/advs.202408416</a>","ama":"Zhou Y, Shaukat A, Seitsonen J, Rigoni C, Timonen JVI, Kostiainen MA. Protein cage directed assembly of binary nanoparticle superlattices. <i>Advanced Science</i>. 2024;11(45). doi:<a href=\"https://doi.org/10.1002/advs.202408416\">10.1002/advs.202408416</a>","mla":"Zhou, Yu, et al. “Protein Cage Directed Assembly of Binary Nanoparticle Superlattices.” <i>Advanced Science</i>, vol. 11, no. 45, 2408416, Wiley, 2024, doi:<a href=\"https://doi.org/10.1002/advs.202408416\">10.1002/advs.202408416</a>.","ieee":"Y. Zhou, A. Shaukat, J. Seitsonen, C. Rigoni, J. V. I. Timonen, and M. A. Kostiainen, “Protein cage directed assembly of binary nanoparticle superlattices,” <i>Advanced Science</i>, vol. 11, no. 45. Wiley, 2024.","chicago":"Zhou, Yu, Ahmed Shaukat, Jani Seitsonen, Carlo Rigoni, Jaakko V.I. Timonen, and Mauri A. Kostiainen. “Protein Cage Directed Assembly of Binary Nanoparticle Superlattices.” <i>Advanced Science</i>. Wiley, 2024. <a href=\"https://doi.org/10.1002/advs.202408416\">https://doi.org/10.1002/advs.202408416</a>.","short":"Y. Zhou, A. Shaukat, J. Seitsonen, C. Rigoni, J.V.I. Timonen, M.A. Kostiainen, Advanced Science 11 (2024)."},"_id":"18451","status":"public","quality_controlled":"1","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"scopus_import":"1","oa":1,"language":[{"iso":"eng"}],"pmid":1,"date_published":"2024-12-04T00:00:00Z","year":"2024","file_date_updated":"2025-01-13T09:16:25Z","article_processing_charge":"Yes","oa_version":"Published Version"}]