---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21015'
abstract:
- lang: eng
text: Early embryo geometry is one of the most invariant species-specific traits,
yet its role in ensuring developmental reproducibility and robustness remains
underexplored. Here we show that in zebrafish, the geometry of the fertilized
egg—specifically its curvature and volume—serves as a critical initial condition
triggering a cascade of events that influence development. The embryo geometry
guides patterned asymmetric cell divisions in the blastoderm, generating radial
gradients of cell volume and nucleocytoplasmic ratio. These gradients generate
mitotic phase waves, with the nucleocytoplasmic ratio determining individual cell
cycle periods independently of other cells. We demonstrate that reducing cell
autonomy reshapes these waves, emphasizing the instructive role of geometry-derived
volume patterns in setting the intrinsic period of the cell cycle oscillator.
In addition to organizing cell cycles, early embryo geometry spatially patterns
zygotic genome activation at the midblastula transition, a key step in establishing
embryonic autonomy. Disrupting the embryo shape alters the zygotic genome activation
pattern and causes ectopic germ layer specification, underscoring the developmental
significance of geometry. Together, our findings reveal a symmetry-breaking function
of early embryo geometry in coordinating cell cycle and transcriptional patterning.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: ScienComp
- _id: LifeSc
acknowledgement: We thank N. Petridou (EMBL) for sharing results before publication.
N.M. was supported by funding from the European Union’s Horizon 2020 programme under
the Marie Skłodowska-Curie COFUND Actions ISTplus grant agreement number 754411.
Y.I.L. acknowledges funding from the European Union’s Horizon 2020 research and
innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413.
The research was supported by funding to C.-P.H. from the NOMIS Foundation, Project
ID 1.844. We would like to thank past and present members of the Heisenberg and
Hannezo groups for discussions, particularly S. Shamipour, V. Doddihal, M. Jovic,
N. Hino, F. N. Arslan, R. Kobylinska and C. Camelo for feedback on the draft manuscript.
This research was supported by the Scientific Service Units (SSU) of Institute of
Science and Technology Austria through resources provided by the Aquatics Facility,
Imaging & Optics Facility (IOF), Scientific Computing (SciComp) facility and Lab
Support Facility (LSF). Open access funding provided by Institute of Science and
Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Nikhil
full_name: Mishra, Nikhil
id: C4D70E82-1081-11EA-B3ED-9A4C3DDC885E
last_name: Mishra
orcid: 0000-0002-6425-5788
- first_name: Yuting I
full_name: Li, Yuting I
id: ee7a5ca8-8b71-11ed-b662-b3341c05b7eb
last_name: Li
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. Geometry-driven asymmetric cell
divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo.
Nature Physics. 2026;22:139-150. doi:10.1038/s41567-025-03122-1
apa: Mishra, N., Li, Y. I., Hannezo, E. B., & Heisenberg, C.-P. J. (2026). Geometry-driven
asymmetric cell divisions pattern cell cycles and zygotic genome activation in
the zebrafish embryo. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-025-03122-1
chicago: Mishra, Nikhil, Yuting I Li, Edouard B Hannezo, and Carl-Philipp J Heisenberg.
“Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome
Activation in the Zebrafish Embryo.” Nature Physics. Springer Nature, 2026.
https://doi.org/10.1038/s41567-025-03122-1.
ieee: N. Mishra, Y. I. Li, E. B. Hannezo, and C.-P. J. Heisenberg, “Geometry-driven
asymmetric cell divisions pattern cell cycles and zygotic genome activation in
the zebrafish embryo,” Nature Physics, vol. 22. Springer Nature, pp. 139–150,
2026.
ista: Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. 2026. Geometry-driven asymmetric
cell divisions pattern cell cycles and zygotic genome activation in the zebrafish
embryo. Nature Physics. 22, 139–150.
mla: Mishra, Nikhil, et al. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell
Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” Nature Physics,
vol. 22, Springer Nature, 2026, pp. 139–50, doi:10.1038/s41567-025-03122-1.
short: N. Mishra, Y.I. Li, E.B. Hannezo, C.-P.J. Heisenberg, Nature Physics 22 (2026)
139–150.
corr_author: '1'
date_created: 2026-01-20T10:12:19Z
date_published: 2026-01-05T00:00:00Z
date_updated: 2026-04-28T12:55:30Z
day: '05'
ddc:
- '570'
department:
- _id: EdHa
- _id: CaHe
doi: 10.1038/s41567-025-03122-1
ec_funded: 1
external_id:
oaworkid:
- W7118187193
file:
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checksum: 0ab7ac2fbcb61a364dba57152db64ed7
content_type: application/pdf
creator: dernst
date_created: 2026-01-21T08:21:11Z
date_updated: 2026-01-21T08:21:11Z
file_id: '21026'
file_name: 2026_NaturePhysics_Mishra.pdf
file_size: 7335694
relation: main_file
success: 1
file_date_updated: 2026-01-21T08:21:11Z
has_accepted_license: '1'
intvolume: ' 22'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '01'
oa: 1
oa_version: Published Version
oaworkid: 1
page: 139-150
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
call_identifier: H2020
grant_number: '101034413'
name: 'IST-BRIDGE: International postdoctoral program'
- _id: 917c023a-16d5-11f0-9cad-eb5cafc52090
name: Cytoplasmic self-organization into cell-like compartments as a common guiding
principle in early animal development
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
issnl:
- ' 1745-2473'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: research_data
url: https://ista.ac.at/en/news/geometry-shapes-life/
scopus_import: '1'
status: public
title: Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome
activation in the zebrafish embryo
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 22
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21485'
abstract:
- lang: eng
text: Insulating oxides are among the most abundant solid materials in the universe1,2,3.
Of the many ways in which they influence natural phenomena, perhaps the most consequential
is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which
occurs even between samples of the same oxide—yet the symmetry-breaking parameter
that causes this remains unidentified11,12. Here we show that adventitious carbonaceous
molecules adsorbed from the environment are the symmetry-breaking factor in same-material
oxide contact electrification (CE). We use acoustic levitation to measure charge
exchange between a sphere and a plate composed of identical amorphous silicon
dioxide (SiO2). Although charging polarity is random for co-prepared samples,
we control it with baking or plasma treatment. Observing the charge-exchange relaxation
afterwards, we see dynamics over a timescale of hours and connect this directly
to the presence of adventitious carbon with time-of-flight mass spectrometry,
low-energy ion scattering and infrared spectroscopy. Going further, we confirm
that adventitious carbon can even determine charge exchange among different oxides.
Our results identify the symmetry-breaking parameter that causes insulating oxides
to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6,
while simultaneously highlighting an overlooked factor in CE more broadly.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: LifeSc
acknowledgement: This project has received support from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
(grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant
agreement no. 754411). We acknowledge the state of Lower Austria and the European
Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges
support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research
was supported by the Scientific Service Units of the Institute of Science and Technology
Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility,
Scientific Computing facility and Lab Support Facility. We thank the Modic group
for the use of the Laue camera, T. Zauner for the photography of the experimental
set-up and R. Möller for insightful discussions. Open access funding provided by
Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Galien M
full_name: Grosjean, Galien M
id: 0C5FDA4A-9CF6-11E9-8939-FF05E6697425
last_name: Grosjean
orcid: 0000-0001-5154-417X
- first_name: Markus
full_name: Ostermann, Markus
last_name: Ostermann
- first_name: Markus
full_name: Sauer, Markus
last_name: Sauer
- first_name: Michael
full_name: Hahn, Michael
last_name: Hahn
- first_name: Christian M.
full_name: Pichler, Christian M.
last_name: Pichler
- first_name: Florian
full_name: Fahrnberger, Florian
last_name: Fahrnberger
- first_name: Felix
full_name: Pertl, Felix
id: 6313aec0-15b2-11ec-abd3-ed67d16139af
last_name: Pertl
orcid: 0000-0003-0463-5794
- first_name: Daniel
full_name: Balazs, Daniel
id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
last_name: Balazs
orcid: 0000-0001-7597-043X
- first_name: Mason M.
full_name: Link, Mason M.
last_name: Link
- first_name: Seong H.
full_name: Kim, Seong H.
last_name: Kim
- first_name: Devin L.
full_name: Schrader, Devin L.
last_name: Schrader
- first_name: Adriana
full_name: Blanco, Adriana
last_name: Blanco
- first_name: Francisco
full_name: Gracia, Francisco
last_name: Gracia
- first_name: Nicolás
full_name: Mujica, Nicolás
last_name: Mujica
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
citation:
ama: Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry
in oxide contact electrification. Nature. 2026;651(8106):626-631. doi:10.1038/s41586-025-10088-w
apa: Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger,
F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide
contact electrification. Nature. Springer Nature. https://doi.org/10.1038/s41586-025-10088-w
chicago: Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian
M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks
Symmetry in Oxide Contact Electrification.” Nature. Springer Nature, 2026.
https://doi.org/10.1038/s41586-025-10088-w.
ieee: G. M. Grosjean et al., “Adventitious carbon breaks symmetry in oxide
contact electrification,” Nature, vol. 651, no. 8106. Springer Nature,
pp. 626–631, 2026.
ista: Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl
F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis
SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification.
Nature. 651(8106), 626–631.
mla: Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact
Electrification.” Nature, vol. 651, no. 8106, Springer Nature, 2026, pp.
626–31, doi:10.1038/s41586-025-10088-w.
short: G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger,
F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia,
N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631.
corr_author: '1'
date_created: 2026-03-23T15:04:00Z
date_published: 2026-03-18T00:00:00Z
date_updated: 2026-04-28T12:06:01Z
day: '18'
ddc:
- '540'
department:
- _id: ScWa
- _id: GradSch
- _id: LifeSc
doi: 10.1038/s41586-025-10088-w
ec_funded: 1
external_id:
pmid:
- '41851325'
file:
- access_level: open_access
checksum: dafef9ed575b44be4263e948a47ae056
content_type: application/pdf
creator: dernst
date_created: 2026-03-24T06:57:08Z
date_updated: 2026-03-24T06:57:08Z
file_id: '21494'
file_name: 2026_Nature_Grosjean.pdf
file_size: 12245694
relation: main_file
success: 1
file_date_updated: 2026-03-24T06:57:08Z
has_accepted_license: '1'
intvolume: ' 651'
issue: '8106'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 626-631
pmid: 1
project:
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
call_identifier: H2020
grant_number: '949120'
name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on ISTA website
relation: press_release
url: https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/
status: public
title: Adventitious carbon breaks symmetry in oxide contact electrification
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 651
year: '2026'
...
---
APC_amount: 1352,08 EUR
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21894'
abstract:
- lang: eng
text: "The Dean–Kawasaki equation—one of the most fundamental SPDEs of\r\nfluctuating
hydrodynamics—has been proposed as a model for density fluctuations in weakly
interacting particle systems. In its original form, it is highly\r\nsingular and
fails to be renormalizable, even by approaches such as regularity structures and
paracontrolled distributions, hindering mathematical approaches to its rigorous
justification. It has been understood recently that it is\r\nnatural to introduce
a suitable regularization, for example, by applying a formal spatial discretization
or by truncating high-frequency noise: This yields\r\nwell-posed equations that
should still precisely approximate the law of the\r\nparticle density fluctuations.\r\nIn
the present work, we prove that a regularization in the form of a formal\r\ndiscretization
of the Dean–Kawasaki equation indeed accurately describes\r\ndensity fluctuations
in systems of weakly interacting diffusing particles: We\r\nshow that, in suitable
weak metrics, the law of fluctuations as predicted by\r\nthe discretized Dean–Kawasaki
SPDE approximates the law of fluctuations\r\nof the original particle system,
up to an error that is of arbitrarily high order in\r\nthe inverse particle number
and a discretization error. In particular, the Dean–\r\nKawasaki equation provides
a means for efficient and accurate simulations of\r\ndensity fluctuations in weakly
interacting particle systems."
acknowledgement: All authors gratefully acknowledge funding from the Austrian Science
Fund (FWF) through the project F65. CR gratefully acknowledges support from the
Austrian Science Fund (FWF), grants P30000, P33010, W1245. FC gratefully acknowledges
funding from the European Union’s Horizon 2020 research and innovation programme
under the Marie Skłodowska-Curie grant agreement No. 754411.
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Federico
full_name: Cornalba, Federico
last_name: Cornalba
- first_name: Julian L
full_name: Fischer, Julian L
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
- first_name: Jonas
full_name: Ingmanns, Jonas
id: 71523d30-15b2-11ec-abd3-f80aa909d6b0
last_name: Ingmanns
orcid: 0009-0008-1310-7946
- first_name: Claudia
full_name: Raithel, Claudia
last_name: Raithel
citation:
ama: Cornalba F, Fischer JL, Ingmanns J, Raithel C. Density fluctuations in weakly
interacting particle systems via the Dean–Kawasaki equation. The Annals of
Probability. 2026;54(1):155-215. doi:10.1214/25-aop1763
apa: Cornalba, F., Fischer, J. L., Ingmanns, J., & Raithel, C. (2026). Density
fluctuations in weakly interacting particle systems via the Dean–Kawasaki equation.
The Annals of Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/25-aop1763
chicago: Cornalba, Federico, Julian L Fischer, Jonas Ingmanns, and Claudia Raithel.
“Density Fluctuations in Weakly Interacting Particle Systems via the Dean–Kawasaki
Equation.” The Annals of Probability. Institute of Mathematical Statistics,
2026. https://doi.org/10.1214/25-aop1763.
ieee: F. Cornalba, J. L. Fischer, J. Ingmanns, and C. Raithel, “Density fluctuations
in weakly interacting particle systems via the Dean–Kawasaki equation,” The
Annals of Probability, vol. 54, no. 1. Institute of Mathematical Statistics,
pp. 155–215, 2026.
ista: Cornalba F, Fischer JL, Ingmanns J, Raithel C. 2026. Density fluctuations
in weakly interacting particle systems via the Dean–Kawasaki equation. The Annals
of Probability. 54(1), 155–215.
mla: Cornalba, Federico, et al. “Density Fluctuations in Weakly Interacting Particle
Systems via the Dean–Kawasaki Equation.” The Annals of Probability, vol.
54, no. 1, Institute of Mathematical Statistics, 2026, pp. 155–215, doi:10.1214/25-aop1763.
short: F. Cornalba, J.L. Fischer, J. Ingmanns, C. Raithel, The Annals of Probability
54 (2026) 155–215.
corr_author: '1'
date_created: 2026-05-20T08:25:25Z
date_published: 2026-01-01T00:00:00Z
date_updated: 2026-05-21T07:21:25Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1214/25-aop1763
ec_funded: 1
external_id:
arxiv:
- '2303.00429'
file:
- access_level: open_access
checksum: 3e60c0e25a1c96342029a7d2b031505f
content_type: application/pdf
creator: dernst
date_created: 2026-05-21T07:11:27Z
date_updated: 2026-05-21T07:11:27Z
file_id: '21906'
file_name: 2026_AnnalsProbability_Cornalba.pdf
file_size: 865745
relation: main_file
success: 1
file_date_updated: 2026-05-21T07:11:27Z
has_accepted_license: '1'
intvolume: ' 54'
issue: '1'
keyword:
- Weakly interacting particle systems
- fluctuating hydrodynamics
- Dean-Kawasaki equation
- stochastic PDEs
- numerical approximation
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 155-215
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
publication: The Annals of Probability
publication_identifier:
eissn:
- 2168-894X
issn:
- 0091-1798
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Density fluctuations in weakly interacting particle systems via the Dean–Kawasaki
equation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '22229'
abstract:
- lang: eng
text: Hippocampal CA3 pyramidal neurons (PNs) form the largest autoassociative network
in the mammalian brain. Whether CA3–CA3 recurrent connectivity is genetically
preconfigured or environmentally shaped during ongoing memory storage is currently
unknown. To address this question, we performed multicellular patch-clamp-based
circuit mapping of up to eight CA3 PNs in the mouse hippocampus at multiple postnatal
time points (P7–8, P18–25, and P45–50). Here, we show that the hippocampal CA3
network undergoes a developmental transformation from local, dense, and random
connectivity to a distributed, sparse, and structured configuration. Thus, sparse
and structured connectivity may emerge via experience-dependent mechanisms. In
parallel, the strength of single synapses is downregulated; single synaptic events
are sufficient to trigger postsynaptic spiking early in development, whereas spatial
summation of several inputs is required at later time points. Biologically inspired
models of memory storage by Hebbian synaptic plasticity and retrieval via pattern
completion suggest that developmental changes improve specific aspects of memory
storage and retrieval. Our results imply a developmental transformation of the
neuronal code and the memory functions in the hippocampal CA3 network.
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: M-Shop
- _id: ScienComp
acknowledgement: 'We thank Jose Guzman, Simon Hippenmeyer, and Tim Vogels for critically
reading the manuscript, Jozsef Csicsvari for useful discussions, Florian Marr for
technical assistance, and Eleftheria Kralli-Beller for manuscript editing. This
research was supported by the Scientific Services Units (SSUs) of ISTA: the preclinical
facility (PCF) provided housing and breeding of the animals, the imaging and optics
facility (IOF) offered technical training and state of the art equipment, the Miba
machine shop contributed to the construction and maintenance of multicellular recording
setups, and the scientific computing unit helped with the large-scale simulations.
The project received funding from the European Union’s Horizon 2020 research and
innovation programme (ERC Advanced Grants No 692692 GIANTSYN and 101199096 CA3-SYNGRAM
to P.J.; Marie Skłodowska-Curie Grant 754411 to V.V.B.; Marie Skłodowska-Curie Grant
101026635 to J.F.W.), the Fond zur Förderung der Wissenschaftlichen Forschung (P
36232-B, PAT4178023, and 10.55776/CoE16 to P.J.), and the Nomis Foundation (fellowship
to A.N.-O.). V.V.B. received funding from a CONACyT fellowship (289638).'
article_number: '5540'
article_processing_charge: Yes
article_type: original
author:
- first_name: Victor M
full_name: Vargas Barroso, Victor M
id: 2F55A9DE-F248-11E8-B48F-1D18A9856A87
last_name: Vargas Barroso
- first_name: Jake
full_name: Watson, Jake
id: 63836096-4690-11EA-BD4E-32803DDC885E
last_name: Watson
orcid: 0000-0002-8698-3823
- first_name: Andrea C
full_name: Navas Olivé, Andrea C
id: 739d26c9-52e8-11ee-8d72-f14d3893b4ce
last_name: Navas Olivé
orcid: 0000-0002-9280-8597
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Vargas Barroso VM, Watson J, Navas Olivé AC, Schlögl A, Jonas PM. Developmental
emergence of sparse and structured synaptic connectivity in the hippocampal CA3
memory circuit. Nature Communications. 2026;17. doi:10.1038/s41467-026-71914-x
apa: Vargas Barroso, V. M., Watson, J., Navas Olivé, A. C., Schlögl, A., & Jonas,
P. M. (2026). Developmental emergence of sparse and structured synaptic connectivity
in the hippocampal CA3 memory circuit. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-026-71914-x
chicago: Vargas Barroso, Victor M, Jake Watson, Andrea C Navas Olivé, Alois Schlögl,
and Peter M Jonas. “Developmental Emergence of Sparse and Structured Synaptic
Connectivity in the Hippocampal CA3 Memory Circuit.” Nature Communications.
Springer Nature, 2026. https://doi.org/10.1038/s41467-026-71914-x.
ieee: V. M. Vargas Barroso, J. Watson, A. C. Navas Olivé, A. Schlögl, and P. M.
Jonas, “Developmental emergence of sparse and structured synaptic connectivity
in the hippocampal CA3 memory circuit,” Nature Communications, vol. 17.
Springer Nature, 2026.
ista: Vargas Barroso VM, Watson J, Navas Olivé AC, Schlögl A, Jonas PM. 2026. Developmental
emergence of sparse and structured synaptic connectivity in the hippocampal CA3
memory circuit. Nature Communications. 17, 5540.
mla: Vargas Barroso, Victor M., et al. “Developmental Emergence of Sparse and Structured
Synaptic Connectivity in the Hippocampal CA3 Memory Circuit.” Nature Communications,
vol. 17, 5540, Springer Nature, 2026, doi:10.1038/s41467-026-71914-x.
short: V.M. Vargas Barroso, J. Watson, A.C. Navas Olivé, A. Schlögl, P.M. Jonas,
Nature Communications 17 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: Source data are provided with this paper. Additional original
data are available from the corresponding author upon request. Code is available
from https://doi.org/10.15479/AT-ISTA-21442 under the link https://research-explorer.ista.ac.at/download/21442/21443/ca3simu-vargas2026v1.tar.gz
date_created: 2026-06-30T13:05:52Z
date_published: 2026-06-23T00:00:00Z
date_updated: 2026-07-01T06:47:49Z
day: '23'
ddc:
- '570'
department:
- _id: PeJo
- _id: ScienComp
doi: 10.1038/s41467-026-71914-x
ec_funded: 1
external_id:
pmid:
- '42014695'
file:
- access_level: open_access
checksum: d0b0093493926985b4c268662ff4d556
content_type: application/pdf
creator: dernst
date_created: 2026-07-01T06:46:06Z
date_updated: 2026-07-01T06:46:06Z
file_id: '22231'
file_name: 2026_NatureComm_VargasBarroso.pdf
file_size: 18304997
relation: main_file
success: 1
file_date_updated: 2026-07-01T06:46:06Z
has_accepted_license: '1'
intvolume: ' 17'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '692692'
name: Biophysics and circuit function of a giant cortical glutamatergic synapse
- _id: e62b56fe-ab3c-11f0-94c7-d181dd352b3b
grant_number: '101199096'
name: Synaptic mechanisms of engram storage and retrieval in CA3 hippocampal microcircuits
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: fc2be41b-9c52-11eb-aca3-faa90aa144e9
call_identifier: H2020
grant_number: '101026635'
name: Synaptic computations of the hippocampal CA3 circuitry
- _id: bd88be38-d553-11ed-ba76-81d5a70a6ef5
grant_number: P36232
name: Mechanisms of GABA release in hippocampal circuits
- _id: 8d9195e9-16d5-11f0-9cad-d075be887a1e
grant_number: PAT 4178023
name: Synaptic networks of human brain
- _id: 26366136-B435-11E9-9278-68D0E5697425
name: Reglas de Conectividad funcional en el hipocampo
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '21442'
relation: research_data
status: public
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Developmental emergence of sparse and structured synaptic connectivity in the
hippocampal CA3 memory circuit
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
OA_type: closed access
_id: '20869'
abstract:
- lang: eng
text: "Premise: What maintains trait divergence in the face of gene flow? Two varieties
of wild snapdragon (Antirrhinum majus) characterized by divergent flower color
hybridize in their native range. Selection on flower color genes is indicated
by sharp clines, but the selective agents have not been demonstrated. Although
previous work has focused on pollinators, pigmentation genes can also contribute
to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates
stress tolerance, which could contribute to hybrid zone maintenance through parental
niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype
mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus,
yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods:
We experimentally compared drought tolerance of each morphotype from allopatric
crosses within and between varieties using three greenhouse treatments. Control
plants were watered as needed, while drought-treated plants were watered half
as often, either from the transplant stage (“early” drought), or from flowering
onset (“late” drought).\r\nResults: Parental morphotypes responded identically
to drought in fitness and most phenotypic traits. However, hybrids had lower survival
(14%) under late drought stress than parental morphotypes (70%). All hybrids that
flowered in the late drought treatment died, compared to ~20% of flowering parental
morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially
contribute to flower color divergence in the face of gene flow in A. majus. Further
research should test the relevance of our results to field conditions and explicitly
probe the role of flower color genes in drought tolerance."
acknowledgement: Thank you to Doug Schemske and Nick Barton forcritically reviewing
the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda
Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg
Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We
sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for
their thoughtfulcomments and suggestions, which substantially improved the clarity
and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon
2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement
No. 754411
article_number: e70129
article_processing_charge: No
article_type: original
author:
- first_name: Alexandre
full_name: Fuster‐Calvo, Alexandre
last_name: Fuster‐Calvo
- first_name: Coline C.
full_name: Jaworski, Coline C.
last_name: Jaworski
- first_name: Thomas
full_name: Ellis, Thomas
id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
last_name: Ellis
orcid: 0000-0002-8511-0254
- first_name: Carina
full_name: Baskett, Carina
id: 3B4A7CE2-F248-11E8-B48F-1D18A9856A87
last_name: Baskett
orcid: 0000-0002-7354-8574
citation:
ama: Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought
stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors.
American Journal of Botany. 2025;112(12). doi:10.1002/ajb2.70129
apa: Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., & Baskett, C. (2025). Reduced
fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with
divergent flower colors. American Journal of Botany. Wiley. https://doi.org/10.1002/ajb2.70129
chicago: Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett.
“Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties
with Divergent Flower Colors.” American Journal of Botany. Wiley, 2025.
https://doi.org/10.1002/ajb2.70129.
ieee: A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness
under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent
flower colors,” American Journal of Botany, vol. 112, no. 12. Wiley, 2025.
ista: Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under
drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower
colors. American Journal of Botany. 112(12), e70129.
mla: Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1
Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” American
Journal of Botany, vol. 112, no. 12, e70129, Wiley, 2025, doi:10.1002/ajb2.70129.
short: A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of
Botany 112 (2025).
date_created: 2025-12-29T12:14:26Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-01-05T11:56:22Z
day: '01'
department:
- _id: NiBa
doi: 10.1002/ajb2.70129
ec_funded: 1
external_id:
pmid:
- '41327576 '
intvolume: ' 112'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: American Journal of Botany
publication_identifier:
eissn:
- 1537-2197
issn:
- 0002-9122
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
link:
- relation: software
url: https://github.com/Alex-Fuster/hybrids_drought
scopus_import: '1'
status: public
title: Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties
with divergent flower colors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2025'
...
---
APC_amount: 7068 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20929'
abstract:
- lang: eng
text: Insulin/insulin-like growth factor signaling inhibits FOXO transcription factors
to control development, homeostasis, and aging. Here, we use proximity labeling
to identify proteins interacting with the C. elegans FOXO DAF-16. We show that
in well-fed, unstressed animals harboring active insulin signaling, DAF-16 forms
a complex with the PAR-1/MARK serine/threonine kinase, a key regulator of cell
polarity. PAR-1 inhibits DAF-16 accumulation and promotes DAF-16 phosphorylation
at S249, at a conserved motif that PAR-1/human MARK2 phosphorylates in vitro.
DAF-2 insulin-like receptor signaling stimulates DAF-16 S249 phosphorylation,
suggesting DAF-2 activates PAR-1. DAF-2 also promotes PAR-1 expression by inhibiting
DAF-16. PAR-1 knockdown, or DAF-16 S249A, prolong lifespan, whereas phosphomimetic
DAF-16 S249D suppresses the longevity of daf-2 mutants. At low insulin signaling,
DAF-16 proximity labeling highlights transcription factors, chromatin regulators,
and DNA repair proteins. One interactor, the zinc finger/homeobox protein ZFH-2/ZFHX3,
forms a complex with DAF-16 and prolongs lifespan. Our work provides entry points
for hypothesis-driven studies of FOXO function and longevity.
acknowledged_ssus:
- _id: Bio
acknowledgement: We thank de Bono lab members for helpful comments on the manuscript,
and the Mass Spec Facility at the Max Perutz Labs, notably WeiQiang Chen and Markus
Hartl, for invaluable discussions and comments on mass spec analyses of worm samples.
All LC-MS/MS analyses were performed on instruments of the Vienna BioCenter Core
Facilities (VBCF). Microscopy was supported by the Scientific Services Units (SSU)
of ISTA through resources provided by the Imaging & Optics Facility (IOF). We are
grateful to Dr. Geraldine Seydoux (Johns Hopkins University) for worm strains and
plasmids, and Dr. Seung-Jae V. Lee (KAIST) for RNAi clones. We are grateful to Ekaterina
Lashmanova for designing the daf-16::TbID::mNG::3xFLAG knock-in construct and for
her outstanding support in the lab. This work was supported by a Wellcome Investigator
Award (209504/A/17/Z) to MdB and an ISTplus Fellowship to MA (Marie Sklodowska-Curie
agreement No 754411).
article_number: '11355'
article_processing_charge: Yes
article_type: original
author:
- first_name: Murat
full_name: Artan, Murat
id: C407B586-6052-11E9-B3AE-7006E6697425
last_name: Artan
orcid: 0000-0001-8945-6992
- first_name: Hanna
full_name: Schön, Hanna
id: C8E17EDC-D7AA-11E9-B7B7-45ECE5697425
last_name: Schön
- first_name: Mario
full_name: De Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: De Bono
orcid: 0000-0001-8347-0443
citation:
ama: Artan M, Schön H, de Bono M. Proximity labeling of DAF-16 FOXO highlights aging
regulatory proteins. Nature Communications. 2025;16. doi:10.1038/s41467-025-66409-0
apa: Artan, M., Schön, H., & de Bono, M. (2025). Proximity labeling of DAF-16
FOXO highlights aging regulatory proteins. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-025-66409-0
chicago: Artan, Murat, Hanna Schön, and Mario de Bono. “Proximity Labeling of DAF-16
FOXO Highlights Aging Regulatory Proteins.” Nature Communications. Springer
Nature, 2025. https://doi.org/10.1038/s41467-025-66409-0.
ieee: M. Artan, H. Schön, and M. de Bono, “Proximity labeling of DAF-16 FOXO highlights
aging regulatory proteins,” Nature Communications, vol. 16. Springer Nature,
2025.
ista: Artan M, Schön H, de Bono M. 2025. Proximity labeling of DAF-16 FOXO highlights
aging regulatory proteins. Nature Communications. 16, 11355.
mla: Artan, Murat, et al. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory
Proteins.” Nature Communications, vol. 16, 11355, Springer Nature, 2025,
doi:10.1038/s41467-025-66409-0.
short: M. Artan, H. Schön, M. de Bono, Nature Communications 16 (2025).
corr_author: '1'
date_created: 2026-01-04T23:01:34Z
date_published: 2025-12-11T00:00:00Z
date_updated: 2026-05-20T08:10:18Z
day: '11'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1038/s41467-025-66409-0
ec_funded: 1
external_id:
pmid:
- '41381452'
file:
- access_level: open_access
checksum: 748e2e003b878b85b6048d51621d6aae
content_type: application/pdf
creator: dernst
date_created: 2026-01-05T10:58:28Z
date_updated: 2026-01-05T10:58:28Z
file_id: '20941'
file_name: 2025_NatureComm_Artan.pdf
file_size: 1642352
relation: main_file
success: 1
file_date_updated: 2026-01-05T10:58:28Z
has_accepted_license: '1'
intvolume: ' 16'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 23870BE8-32DE-11EA-91FC-C7463DDC885E
grant_number: 209504/A/17/Z
name: Molecular mechanisms of neural circuit function
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2025'
...
---
OA_type: closed access
_id: '18765'
abstract:
- lang: eng
text: Mosaic Analysis with Double Markers (MADM) represents a mouse genetic approach
coupling differential fluorescent labeling to genetic manipulations in dividing
cells and their lineages. MADM uniquely enables the generation and visualization
of individual control or homozygous mutant cells in a heterozygous genetic environment.
Among its diverse applications, MADM has been used to dissect cell-autonomous
gene functions important for cortical development and neural development in general.
The high cellular resolution offered by MADM also permits the analysis of transcriptomic
changes of individual cells upon genetic manipulations. In this chapter, we describe
an experimental protocol combining the generation and isolation of MADM-labeled
cells with downstream single-cell RNA-sequencing technologies to probe cell-type
specific phenotypes due to genetic mutations at single-cell resolution.
acknowledged_ssus:
- _id: Bio
acknowledgement: 'We thank all Hippenmeyer lab members for support and discussions.
Experimental steps described were optimized with support provided by the Imaging
& Optics Facility (IOF) and Preclinical Facility (PCF) at ISTA, Vienna BioCenter
Core Facilities (VBCF), and Christoph Bock lab at Center for Molecular Medicine
(CeMM). G.C. received funding from European Commission (IST plus postdoctoral fellowship).
This work was supported by ISTA institutional funds: The Austrian Science Fund Special
Research Programmes (FWF SFB F78 Neuro Stem Modulation) to S.H.'
alternative_title:
- Methods in Molecular Biology
article_processing_charge: No
author:
- first_name: Giselle T
full_name: Cheung, Giselle T
id: 471195F6-F248-11E8-B48F-1D18A9856A87
last_name: Cheung
orcid: 0000-0001-8457-2572
- first_name: Florian
full_name: Pauler, Florian
id: 48EA0138-F248-11E8-B48F-1D18A9856A87
last_name: Pauler
orcid: 0000-0002-7462-0048
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: 'Cheung GT, Pauler F, Hippenmeyer S. Probing Cell-Type Specificity of Mutant
Phenotype at Transcriptomic Level Using Mosaic Analysis with Double Markers (MADM).
In: Garcia-Marques J, Lee T, eds. Lineage Tracing. Vol 2886. MIMB. New
York, NY: Springer Nature; 2025:139-151. doi:10.1007/978-1-0716-4310-5_7'
apa: 'Cheung, G. T., Pauler, F., & Hippenmeyer, S. (2025). Probing Cell-Type
Specificity of Mutant Phenotype at Transcriptomic Level Using Mosaic Analysis
with Double Markers (MADM). In J. Garcia-Marques & T. Lee (Eds.), Lineage
Tracing (Vol. 2886, pp. 139–151). New York, NY: Springer Nature. https://doi.org/10.1007/978-1-0716-4310-5_7'
chicago: 'Cheung, Giselle T, Florian Pauler, and Simon Hippenmeyer. “Probing Cell-Type
Specificity of Mutant Phenotype at Transcriptomic Level Using Mosaic Analysis
with Double Markers (MADM).” In Lineage Tracing, edited by Jorge Garcia-Marques
and Tzumin Lee, 2886:139–51. MIMB. New York, NY: Springer Nature, 2025. https://doi.org/10.1007/978-1-0716-4310-5_7.'
ieee: 'G. T. Cheung, F. Pauler, and S. Hippenmeyer, “Probing Cell-Type Specificity
of Mutant Phenotype at Transcriptomic Level Using Mosaic Analysis with Double
Markers (MADM),” in Lineage Tracing, vol. 2886, J. Garcia-Marques and T.
Lee, Eds. New York, NY: Springer Nature, 2025, pp. 139–151.'
ista: 'Cheung GT, Pauler F, Hippenmeyer S. 2025.Probing Cell-Type Specificity of
Mutant Phenotype at Transcriptomic Level Using Mosaic Analysis with Double Markers
(MADM). In: Lineage Tracing. Methods in Molecular Biology, vol. 2886, 139–151.'
mla: Cheung, Giselle T., et al. “Probing Cell-Type Specificity of Mutant Phenotype
at Transcriptomic Level Using Mosaic Analysis with Double Markers (MADM).” Lineage
Tracing, edited by Jorge Garcia-Marques and Tzumin Lee, vol. 2886, Springer
Nature, 2025, pp. 139–51, doi:10.1007/978-1-0716-4310-5_7.
short: G.T. Cheung, F. Pauler, S. Hippenmeyer, in:, J. Garcia-Marques, T. Lee (Eds.),
Lineage Tracing, Springer Nature, New York, NY, 2025, pp. 139–151.
corr_author: '1'
date_created: 2025-01-07T08:36:47Z
date_published: 2025-01-03T00:00:00Z
date_updated: 2025-04-14T07:43:46Z
day: '03'
department:
- _id: SiHi
doi: 10.1007/978-1-0716-4310-5_7
ec_funded: 1
editor:
- first_name: Jorge
full_name: Garcia-Marques, Jorge
last_name: Garcia-Marques
- first_name: Tzumin
full_name: Lee, Tzumin
last_name: Lee
external_id:
pmid:
- '39745639'
intvolume: ' 2886'
language:
- iso: eng
month: '01'
oa_version: None
page: 139-151
place: New York, NY
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Lineage Tracing
publication_identifier:
eisbn:
- '9781071643105'
eissn:
- 1940-6029
isbn:
- '9781071643099'
issn:
- 1064-3745
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: MIMB
status: public
title: Probing Cell-Type Specificity of Mutant Phenotype at Transcriptomic Level Using
Mosaic Analysis with Double Markers (MADM)
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2886
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '19003'
abstract:
- lang: eng
text: 'Super-resolution methods provide far better spatial resolution than the optical
diffraction limit of about half the wavelength of light (∼200-300 nm). Nevertheless,
they have yet to attain widespread use in plants, largely due to plants’ challenging
optical properties. Expansion microscopy improves effective resolution by isotropically
increasing the physical distances between sample structures while preserving relative
spatial arrangements and clearing the sample. However, its application to plants
has been hindered by the rigid, mechanically cohesive structure of plant tissues.
Here, we report on whole-mount expansion microscopy of thale cress (Arabidopsis
thaliana) root tissues (PlantEx), achieving a four-fold resolution increase over
conventional microscopy. Our results highlight the microtubule cytoskeleton organization
and interaction between molecularly defined cellular constituents. Combining PlantEx
with stimulated emission depletion (STED) microscopy, we increase nanoscale resolution
and visualize the complex organization of subcellular organelles from intact tissues
by example of the densely packed COPI-coated vesicles associated with the Golgi
apparatus and put these into a cellular structural context. Our results show that
expansion microscopy can be applied to increase effective imaging resolution in
Arabidopsis root specimens. '
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: E-Lib
- _id: M-Shop
acknowledgement: "We gratefully acknowledge support by the Scientific Service Units
at ISTA, including the Imaging and Optics and Lab Support facilities and the mechanical
workshop and Library. We thank Philipp Velicky for STED microscope alignment.\r\nThis
project has received funding from the European Research Council under the Horizon
2020 Framework Programme (grant agreement No 742985, J.F.). It has also received
funding from the Horizon 2020 Framework Programme under the Marie Skłodowska-Curie
Grant Agreement No. 665385 (M.G.). S.T. has received funding as an ISTplus Fellow
from the Horizon 2020 Framework Programme under Marie Skłodowska-Curie grant agreement
no. 754411 and from EMBO via a Long-Term Fellowship (grant number ALTF 679-2018).
M.R.T. received funding from the Austrian Academy of Sciences with DOC fellowship
no. 26137. The project has further received funding from the Austrian Science Fund,
via grant DK W1232 (M.R.T., N.A.D., and J.G.D). W.J. received a postdoctoral fellowship
from the Human Frontier Science Program (LT000557/2018). The funders had no role
in study design, data collection and analysis, decision to publish or preparation
of the manuscript."
article_number: koaf006
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Michelle C
full_name: Gallei, Michelle C
id: 35A03822-F248-11E8-B48F-1D18A9856A87
last_name: Gallei
orcid: 0000-0003-1286-7368
- first_name: Sven M
full_name: Truckenbrodt, Sven M
id: 45812BD4-F248-11E8-B48F-1D18A9856A87
last_name: Truckenbrodt
- first_name: Caroline
full_name: Kreuzinger, Caroline
id: 382077BA-F248-11E8-B48F-1D18A9856A87
last_name: Kreuzinger
- first_name: Syamala
full_name: Inumella, Syamala
id: F8660870-D756-11E9-98C5-34DFE5697425
last_name: Inumella
orcid: 0009-0002-5890-120X
- first_name: Vitali
full_name: Vistunou, Vitali
id: 7e146587-8972-11ed-ae7b-d7a32ea86a81
last_name: Vistunou
- first_name: Christoph M
full_name: Sommer, Christoph M
id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
last_name: Sommer
orcid: 0000-0003-1216-9105
- first_name: Mojtaba
full_name: Tavakoli, Mojtaba
id: 3A0A06F4-F248-11E8-B48F-1D18A9856A87
last_name: Tavakoli
orcid: 0000-0002-7667-6854
- first_name: Nathalie
full_name: Agudelo Duenas, Nathalie
id: 40E7F008-F248-11E8-B48F-1D18A9856A87
last_name: Agudelo Duenas
- first_name: Jakob
full_name: Vorlaufer, Jakob
id: 937696FA-C996-11E9-8C7C-CF13E6697425
last_name: Vorlaufer
orcid: 0009-0000-7590-3501
- first_name: Wiebke
full_name: Jahr, Wiebke
id: 425C1CE8-F248-11E8-B48F-1D18A9856A87
last_name: Jahr
orcid: 0000-0003-0201-2315
- first_name: Marek
full_name: Randuch, Marek
id: 6ac4636d-15b2-11ec-abd3-fb8df79972ae
last_name: Randuch
- first_name: Alexander J
full_name: Johnson, Alexander J
id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
last_name: Johnson
orcid: 0000-0002-2739-8843
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
citation:
ama: Gallei MC, Truckenbrodt SM, Kreuzinger C, et al. Super-resolution expansion
microscopy in plant roots. The Plant Cell. 2025;37(4). doi:10.1093/plcell/koaf006
apa: Gallei, M. C., Truckenbrodt, S. M., Kreuzinger, C., Inumella, S., Vistunou,
V., Sommer, C. M., … Danzl, J. G. (2025). Super-resolution expansion microscopy
in plant roots. The Plant Cell. Oxford University Press. https://doi.org/10.1093/plcell/koaf006
chicago: Gallei, Michelle C, Sven M Truckenbrodt, Caroline Kreuzinger, Syamala Inumella,
Vitali Vistunou, Christoph M Sommer, Mojtaba Tavakoli, et al. “Super-Resolution
Expansion Microscopy in Plant Roots.” The Plant Cell. Oxford University
Press, 2025. https://doi.org/10.1093/plcell/koaf006.
ieee: M. C. Gallei et al., “Super-resolution expansion microscopy in plant
roots,” The Plant Cell, vol. 37, no. 4. Oxford University Press, 2025.
ista: Gallei MC, Truckenbrodt SM, Kreuzinger C, Inumella S, Vistunou V, Sommer CM,
Tavakoli M, Agudelo Duenas N, Vorlaufer J, Jahr W, Randuch M, Johnson AJ, Benková
E, Friml J, Danzl JG. 2025. Super-resolution expansion microscopy in plant roots.
The Plant Cell. 37(4), koaf006.
mla: Gallei, Michelle C., et al. “Super-Resolution Expansion Microscopy in Plant
Roots.” The Plant Cell, vol. 37, no. 4, koaf006, Oxford University Press,
2025, doi:10.1093/plcell/koaf006.
short: M.C. Gallei, S.M. Truckenbrodt, C. Kreuzinger, S. Inumella, V. Vistunou,
C.M. Sommer, M. Tavakoli, N. Agudelo Duenas, J. Vorlaufer, W. Jahr, M. Randuch,
A.J. Johnson, E. Benková, J. Friml, J.G. Danzl, The Plant Cell 37 (2025).
corr_author: '1'
date_created: 2025-02-05T06:52:06Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2026-06-10T08:30:19Z
day: '01'
ddc:
- '580'
department:
- _id: EvBe
- _id: JoDa
- _id: JiFr
doi: 10.1093/plcell/koaf006
ec_funded: 1
external_id:
isi:
- '001462763100001'
pmid:
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grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
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grant_number: '665385'
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call_identifier: H2020
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grant_number: ALTF 679-2018
name: UltraX - achieving sub-nanometer resolution in light microscopy using iterative
X10 microscopy in combination with nanobodies and STED
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grant_number: '26137'
name: Studying Organelle Structure and Function at Nanoscale Resolution with Expansion
Microscopy
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call_identifier: FWF
grant_number: W1232-B24
name: Molecular Drug Targets
publication: The Plant Cell
publication_identifier:
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publication_status: published
publisher: Oxford University Press
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title: Super-resolution expansion microscopy in plant roots
tmp:
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type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
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_id: '19074'
abstract:
- lang: eng
text: 'The public goods game is among the most studied metaphors of cooperation
in groups. In this game, individuals can use their endowments to make contributions
towards a good that benefits everyone. Each individual, however, is tempted to
free-ride on the contributions of others. Herein, we study repeated public goods
games among asymmetric players. Previous work has explored to which extent asymmetry
allows for full cooperation, such that players contribute their full endowment
each round. However, by design that work focusses on equilibria where individuals
make the same contribution each round. Instead, here we consider players whose
contributions along the equilibrium path can change from one round to the next.
We do so for three different models – one without any budget constraints, one
with endowment constraints, and one in which individuals can save their current
endowment to be used in subsequent rounds. In each case, we explore two key quantities:
the welfare and the resource efficiency that can be achieved in equilibrium. Welfare
corresponds to the sum of all players’ payoffs. Resource efficiency relates this
welfare to the total contributions made by the players. Compared to constant contribution
sequences, we find that time-dependent contributions can improve resource efficiency
across all three models. Moreover, they can improve the players’ welfare in the
model with savings.'
acknowledgement: 'This work was supported by the European Research Council CoG 863818
(ForM-SMArt) (to K.C.) and the European Research Council Starting Grant 850529:
E-DIRECT (to C.H.), the European Union’s Horizon 2020 research and innovation programme
under the Marie Skłodowska-Curie Grant Agreement #754411 and the French Agence Nationale
de la Recherche (under the Investissement d’Avenir programme, ANR-17-EURE-0010),
and ARC SRIEAS Grant SR200100005 Securing Antarctica’s Environmental Future (to
M.K.). Open access funding provided by Institute of Science and Technology (IST
Austria).'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Valentin
full_name: Hübner, Valentin
id: 2c8aa207-dc7d-11ea-9b2f-f22972ecd910
last_name: Hübner
orcid: 0009-0001-5009-4987
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Manuel
full_name: Staab, Manuel
last_name: Staab
- first_name: Maria
full_name: Kleshnina, Maria
id: 4E21749C-F248-11E8-B48F-1D18A9856A87
last_name: Kleshnina
orcid: 0000-0002-5518-8317
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Hübner V, Hilbe C, Staab M, Kleshnina M, Chatterjee K. Time-dependent strategies
in repeated asymmetric public goods games. Dynamic Games and Applications.
2025;15:1617-1645. doi:10.1007/s13235-025-00627-5
apa: Hübner, V., Hilbe, C., Staab, M., Kleshnina, M., & Chatterjee, K. (2025).
Time-dependent strategies in repeated asymmetric public goods games. Dynamic
Games and Applications. Springer Nature. https://doi.org/10.1007/s13235-025-00627-5
chicago: Hübner, Valentin, Christian Hilbe, Manuel Staab, Maria Kleshnina, and Krishnendu
Chatterjee. “Time-Dependent Strategies in Repeated Asymmetric Public Goods Games.”
Dynamic Games and Applications. Springer Nature, 2025. https://doi.org/10.1007/s13235-025-00627-5.
ieee: V. Hübner, C. Hilbe, M. Staab, M. Kleshnina, and K. Chatterjee, “Time-dependent
strategies in repeated asymmetric public goods games,” Dynamic Games and Applications,
vol. 15. Springer Nature, pp. 1617–1645, 2025.
ista: Hübner V, Hilbe C, Staab M, Kleshnina M, Chatterjee K. 2025. Time-dependent
strategies in repeated asymmetric public goods games. Dynamic Games and Applications.
15, 1617–1645.
mla: Hübner, Valentin, et al. “Time-Dependent Strategies in Repeated Asymmetric
Public Goods Games.” Dynamic Games and Applications, vol. 15, Springer
Nature, 2025, pp. 1617–45, doi:10.1007/s13235-025-00627-5.
short: V. Hübner, C. Hilbe, M. Staab, M. Kleshnina, K. Chatterjee, Dynamic Games
and Applications 15 (2025) 1617–1645.
corr_author: '1'
date_created: 2025-02-23T23:01:57Z
date_published: 2025-11-01T00:00:00Z
date_updated: 2026-04-07T12:30:56Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/s13235-025-00627-5
ec_funded: 1
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month: '11'
oa: 1
oa_version: Published Version
page: 1617-1645
project:
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call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Dynamic Games and Applications
publication_identifier:
eissn:
- 2153-0793
issn:
- 2153-0785
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
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relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Time-dependent strategies in repeated asymmetric public goods games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2025'
...
---
OA_place: publisher
_id: '19903'
abstract:
- lang: eng
text: "Cooperation, that is, one person paying a cost for another's benefit, is
a fundamental principle without which no form of society could exist. The extent
to which humans cooperate with each other is also an essential feature that differentiates
them from other animals. Cooperation occurs even in the absence of altruistic
motivations, when it is selfishly incentivised by the expectation of a future
reward. For example, many economic interactions are well described that way. This
kind of cooperation requires that people exhibit reciprocal behaviour that acts
as a mechanism that rewards cooperation.\r\nWith game-theoretic models, it is
possible to formally study potential such mechanisms and under what conditions
they can exist. This thesis contributes to this effort by analysing recently introduced
models of cooperation that advance on previous work by taking into account the
potential for pre-existing inequality among cooperating individuals as well as
the different forms that reciprocity can take.\r\nIndividuals may differ both
intrinsically, in their abilities, as well as extrinsically, in the amount of
resources they have available. Allowing for such differences in a model of cooperation
helps to understand how inequality affects the potential for, and outcomes of,
cooperation among unequals. In this thesis, it is shown that in the presence of
intrinsic inequality, a similar unequal distribution of resources can increase
the potential for cooperation. This effect is stronger the smaller the group is
in which cooperation takes place. It is also shown that under particular assumptions,
if the unequal members of a group vary the size of their contributions to a cooperative
effort over time, they can thereby increase their efficiency and improve the collective
outcome.\r\nCooperative behaviour in a two-person interaction can be rewarded
either by direct reciprocation whenever the same two people interact again, or
indirectly by a third party who observed the interaction. In the latter case of
indirect reciprocity, individuals are proximally rewarded by a good reputation,
which ultimately translates to being rewarded with cooperative behaviour by others.
This mechanism can enable selfishly motivated cooperation even in circumstances
where individuals are unlikely to meet again, akin to how money facilitates trade.
While these two forms of reciprocity have mostly been studied in isolation, this
thesis analyses both direct and indirect reciprocity in a general model in order
to compare their relative effectiveness under different circumstances. The contribution
of this thesis is an extension of previous work regarding a specific kind of interaction,
whose parameters allow for convenient mathematical analysis, to the most general
set of possible interactions."
acknowledgement: "The research for this thesis was supported by the European Research
Council\r\n(grant agreements No. 863818 and No. 850529), the European Union’s Horizon
2020 research and innovation programme (Marie Skłodowska-Curie grant agreement No.
754411),\r\nthe Austrian Science Fund (grant DOI 10.55776/COE12), the French Agence
Nationale\r\nde la Recherche under the Programme d’investissements d’avenir (project
reference 17-\r\nEURE-0010) and the Australian Government through the Australian
Research Council\r\n(grant No. SR200100005, “Securing Antarctica’s Environmental
Future”)."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Valentin
full_name: Hübner, Valentin
id: 2c8aa207-dc7d-11ea-9b2f-f22972ecd910
last_name: Hübner
orcid: 0009-0001-5009-4987
citation:
ama: Hübner V. Reciprocity and inequality in social dilemmas. 2025. doi:10.15479/AT-ISTA-19903
apa: Hübner, V. (2025). Reciprocity and inequality in social dilemmas. Institute
of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-19903
chicago: Hübner, Valentin. “Reciprocity and Inequality in Social Dilemmas.” Institute
of Science and Technology Austria, 2025. https://doi.org/10.15479/AT-ISTA-19903.
ieee: V. Hübner, “Reciprocity and inequality in social dilemmas,” Institute of Science
and Technology Austria, 2025.
ista: Hübner V. 2025. Reciprocity and inequality in social dilemmas. Institute of
Science and Technology Austria.
mla: Hübner, Valentin. Reciprocity and Inequality in Social Dilemmas. Institute
of Science and Technology Austria, 2025, doi:10.15479/AT-ISTA-19903.
short: V. Hübner, Reciprocity and Inequality in Social Dilemmas, Institute of Science
and Technology Austria, 2025.
corr_author: '1'
date_created: 2025-06-25T13:50:10Z
date_published: 2025-06-25T00:00:00Z
date_updated: 2026-04-07T12:30:57Z
day: '25'
ddc:
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrCh
doi: 10.15479/AT-ISTA-19903
ec_funded: 1
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language:
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license: https://creativecommons.org/licenses/by-nc/4.0/
month: '06'
oa: 1
oa_version: Published Version
page: '157'
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
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status: public
- id: '15083'
relation: part_of_dissertation
status: public
- id: '19074'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
title: Reciprocity and inequality in social dilemmas
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20099'
abstract:
- lang: eng
text: The hippocampus, critical for learning and memory, is dogmatically described
as a trisynaptic circuit where dentate gyrus granule cells (GCs), CA3 pyramidal
neurons (PNs), and CA1 PNs are serially connected. However, CA3 also forms an
autoassociative network, and its PNs have diverse morphologies, intrinsic properties,
and GC input levels. How PN subtypes compose this recurrent network is unknown.
To determine the synaptic arrangement of identified CA3 PNs, we combine multicellular
patch-clamp recording and post hoc morphological analysis in mouse hippocampal
slices. PNs can be divided into distinct “superficial” and “deep” subclasses,
the latter including previously reported “athorny” cells. Subclasses have distinct
input-output transformations and asymmetric connectivity, which is more abundant
from superficial to deep PNs, splitting CA3 locally into two parallel recurrent
networks. Coincident spontaneous inhibition occurs frequently within but not between
subclasses, implying subclass-specific inhibitory innervation. Our results suggest
two separately controlled sublayers for parallel information processing in hippocampal
CA3.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
- _id: LifeSc
- _id: M-Shop
acknowledgement: We thank Andrea Navas-Olive and Rebecca J. Morse-Mora for critically
reading an earlier version of the manuscript. We also thank Florian Marr and Christina
Altmutter for excellent technical assistance, Alois Schlögl for programming and
data-handling assistance, Todor Asenov for technical support, and Eleftheria Kralli-Beller
for manuscript editing. This research was supported by the Scientific Services Units
(SSUs) of ISTA. We are particularly grateful for assistance from the Imaging and
Optics Facility, Preclinical Facility, Lab Support Facility, and Miba Machine Shop.
The project received funding from the European Research Council (ERC) under the
European Union’s Horizon 2020 research and innovation program (grant agreement no.
692692 to P.J., Marie Skłodowska-Curie Actions Individual Fellowship no. 101026635
to J.F.W., and an ISTplus Fellowship through Marie Skłodowska-Curie grant agreement
no. 754411 to V.V.-B.), the Austrian Science Fund (P 36232-B, PAT 4178023, and Cluster
of Excellence 10.55776/COE16 to P.J.), and a CONACyT fellowship (289638 to V.V.-B.)
and was supported by a non-stipendiary EMBO fellowship (ALTF 756–2020 to J.F.W.).
article_number: '116080'
article_processing_charge: Yes
article_type: original
author:
- first_name: Jake
full_name: Watson, Jake
id: 63836096-4690-11EA-BD4E-32803DDC885E
last_name: Watson
orcid: 0000-0002-8698-3823
- first_name: Victor M
full_name: Vargas Barroso, Victor M
id: 2F55A9DE-F248-11E8-B48F-1D18A9856A87
last_name: Vargas Barroso
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Watson J, Vargas Barroso VM, Jonas PM. Cell-specific wiring routes information
flow through hippocampal CA3. Cell Reports. 2025;44(8). doi:10.1016/j.celrep.2025.116080
apa: Watson, J., Vargas Barroso, V. M., & Jonas, P. M. (2025). Cell-specific
wiring routes information flow through hippocampal CA3. Cell Reports. Elsevier.
https://doi.org/10.1016/j.celrep.2025.116080
chicago: Watson, Jake, Victor M Vargas Barroso, and Peter M Jonas. “Cell-Specific
Wiring Routes Information Flow through Hippocampal CA3.” Cell Reports.
Elsevier, 2025. https://doi.org/10.1016/j.celrep.2025.116080.
ieee: J. Watson, V. M. Vargas Barroso, and P. M. Jonas, “Cell-specific wiring routes
information flow through hippocampal CA3,” Cell Reports, vol. 44, no. 8.
Elsevier, 2025.
ista: Watson J, Vargas Barroso VM, Jonas PM. 2025. Cell-specific wiring routes information
flow through hippocampal CA3. Cell Reports. 44(8), 116080.
mla: Watson, Jake, et al. “Cell-Specific Wiring Routes Information Flow through
Hippocampal CA3.” Cell Reports, vol. 44, no. 8, 116080, Elsevier, 2025,
doi:10.1016/j.celrep.2025.116080.
short: J. Watson, V.M. Vargas Barroso, P.M. Jonas, Cell Reports 44 (2025).
corr_author: '1'
date_created: 2025-08-03T22:01:30Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-09-30T14:12:02Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.celrep.2025.116080
ec_funded: 1
external_id:
isi:
- '001544472300002'
file:
- access_level: open_access
checksum: 556ff9760661ecd23949d75031043b1f
content_type: application/pdf
creator: dernst
date_created: 2025-08-04T06:53:07Z
date_updated: 2025-08-04T06:53:07Z
file_id: '20106'
file_name: 2025_CellReports_Watson.pdf
file_size: 27695214
relation: main_file
success: 1
file_date_updated: 2025-08-04T06:53:07Z
has_accepted_license: '1'
intvolume: ' 44'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '692692'
name: Biophysics and circuit function of a giant cortical glutamatergic synapse
- _id: fc2be41b-9c52-11eb-aca3-faa90aa144e9
call_identifier: H2020
grant_number: '101026635'
name: Synaptic computations of the hippocampal CA3 circuitry
- _id: bd88be38-d553-11ed-ba76-81d5a70a6ef5
grant_number: P36232
name: Mechanisms of GABA release in hippocampal circuits
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Cell Reports
publication_identifier:
eissn:
- 2211-1247
issn:
- 2639-1856
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell-specific wiring routes information flow through hippocampal CA3
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 44
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20260'
abstract:
- lang: eng
text: The medial axis of a set consists of the points in the ambient space without
a unique closest point in the original set. Since its introduction, the medial
axis has been used extensively in many applications as a method of computing a
skeleton topologically equivalent to the original set. Unfortunately, one limiting
factor in the use of the medial axis of a smooth manifold is that it is not necessarily
topologically stable under small perturbations of the manifold. To counter these
instabilities, various prunings of the medial axis have been proposed in the computational
geometry community. Here, we examine one type of pruning, called burning. Because
of the good experimental results it was hoped that the burning method of simplifying
the medial axis would be stable. In this work, we show a simple example that dashes
such hopes. Based on Bing’s house with two rooms, we demonstrate an isotopy of
a shape where the medial axis goes from collapsible to non-collapsible. More precisely,
we consider the standard deformation retract from the closed ball to Bing’s house
with two rooms, but stop just short of the point where Bing’s house becomes two
dimensional. This way we obtain an isotopy from the 3-ball to a thickened version
of Bing’s house. Under this isotopy, the medial axis goes from collapsible to
non-collapsible. We stress that this isotopy can be made generic, in the sense
of singularity theory, as developed by Arnol’d and Thom.
acknowledgement: "We thank André Lieutier, David Letscher, Ellen Gasparovic, Kathryn
Leonard, and Tao Ju for early discussions on this work. We also thank Lu Liu, Yajie
Yan, and Tao Ju for sharing code to generate the examples. We further thank Abigail
Thompson for discussion on the conjecture and James Damon for sharing his insight
in singularity theory. We thank the reviewers for their detailed reviews, which
helped to improve the exposition.\r\nOpen access funding provided by Institute of
Science and Technology (IST Austria). Partially supported by the DFG Collaborative
Research Center TRR 109, ‘Discretization in Geometry and Dynamics’ and the European
Research Council (ERC), grant no. 788183, ‘Alpha Shape Theory Extended’. The first
author was supported in part by the National Science Foundation through grants DBI-1759807,
CCF-1907612, and CCF-2444309. The fourth author was supported by the European Union’s
Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
grant agreement No. 754411, the Austrian science fund (FWF) M-3073, ANR grant StratMesh,
ANR-24-CE48-1899, and the welcome package from IDEX of the Université Côte d’Azur,
ANR-15-IDEX-01."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Erin Wolf
full_name: Chambers, Erin Wolf
last_name: Chambers
- first_name: Christopher D
full_name: Fillmore, Christopher D
id: 35638A5C-AAC7-11E9-B0BF-5503E6697425
last_name: Fillmore
- first_name: Elizabeth R
full_name: Stephenson, Elizabeth R
id: 2D04F932-F248-11E8-B48F-1D18A9856A87
last_name: Stephenson
orcid: 0000-0002-6862-208X
- first_name: Mathijs
full_name: Wintraecken, Mathijs
id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
last_name: Wintraecken
orcid: 0000-0002-7472-2220
citation:
ama: Chambers EW, Fillmore CD, Stephenson ER, Wintraecken M. Burning or collapsing
the medial axis is unstable. La Matematica. 2025;4:811-828. doi:10.1007/s44007-025-00170-0
apa: Chambers, E. W., Fillmore, C. D., Stephenson, E. R., & Wintraecken, M.
(2025). Burning or collapsing the medial axis is unstable. La Matematica.
Springer Nature. https://doi.org/10.1007/s44007-025-00170-0
chicago: Chambers, Erin Wolf, Christopher D Fillmore, Elizabeth R Stephenson, and
Mathijs Wintraecken. “Burning or Collapsing the Medial Axis Is Unstable.” La
Matematica. Springer Nature, 2025. https://doi.org/10.1007/s44007-025-00170-0.
ieee: E. W. Chambers, C. D. Fillmore, E. R. Stephenson, and M. Wintraecken, “Burning
or collapsing the medial axis is unstable,” La Matematica, vol. 4. Springer
Nature, pp. 811–828, 2025.
ista: Chambers EW, Fillmore CD, Stephenson ER, Wintraecken M. 2025. Burning or collapsing
the medial axis is unstable. La Matematica. 4, 811–828.
mla: Chambers, Erin Wolf, et al. “Burning or Collapsing the Medial Axis Is Unstable.”
La Matematica, vol. 4, Springer Nature, 2025, pp. 811–28, doi:10.1007/s44007-025-00170-0.
short: E.W. Chambers, C.D. Fillmore, E.R. Stephenson, M. Wintraecken, La Matematica
4 (2025) 811–828.
corr_author: '1'
date_created: 2025-08-31T22:01:33Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-04-07T11:42:48Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s44007-025-00170-0
ec_funded: 1
file:
- access_level: open_access
checksum: e2043259194bfcdf3d74c4da8a5a853f
content_type: application/pdf
creator: dernst
date_created: 2025-12-30T07:52:58Z
date_updated: 2025-12-30T07:52:58Z
file_id: '20885'
file_name: 2025_LaMatematica_Chambers.pdf
file_size: 2678640
relation: main_file
success: 1
file_date_updated: 2025-12-30T07:52:58Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 811-828
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '788183'
name: Alpha Shape Theory Extended
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
grant_number: M03073
name: Learning and triangulating manifolds via collapses
publication: La Matematica
publication_identifier:
eissn:
- 2730-9657
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '21021'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Burning or collapsing the medial axis is unstable
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20324'
abstract:
- lang: eng
text: We report relaxation oscillations in a one-dimensional array of Josephson
junctions, wherein the array dynamically switches between low-current and high-current
states. The oscillations are current-voltage dual to those ordinarily observed
in single junctions. The current-voltage dual circuit quantitatively accounts
for temporal dynamics of the array, including the dependence on biasing conditions.
Injection locking of the oscillations results in well-developed current plateaux.
A thermal model explains the self-consistent reduction of the superconducting
gap due to overheating of the array in the high-current state. Our work suggests
that overheating determines the switching from the high-current state to the low-current
state.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
acknowledgement: We gratefully acknowledge support from the Miba Machine Shop and
the Nanofabrictation Facility at IST Austria. This work was supported by the Austrian
FWF under Grant No. P33692-N (S.M., J.S., and A.P.H.), the European Union’s Horizon
2020 research and innovation program under Marie Skłodowska-Curie Grant Agreement
No. 754411 (J.S.), and a NOMIS Foundation research grant (A.P.H.).
article_number: '014035'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Soham
full_name: Mukhopadhyay, Soham
id: FDE60288-A89D-11E9-947F-1AF6E5697425
last_name: Mukhopadhyay
orcid: 0000-0001-5263-5559
- first_name: Diego A
full_name: Lancheros Naranjo, Diego A
id: 6c55e976-15b2-11ec-abd3-d790e8937fde
last_name: Lancheros Naranjo
- first_name: Jorden L
full_name: Senior, Jorden L
id: 5479D234-2D30-11EA-89CC-40953DDC885E
last_name: Senior
orcid: 0000-0002-0672-9295
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
citation:
ama: Mukhopadhyay S, Lancheros Naranjo DA, Senior JL, Higginbotham AP. Dual relaxation
oscillations in a Josephson-junction array. Physical Review Applied. 2025;24.
doi:10.1103/qvls-7s3q
apa: Mukhopadhyay, S., Lancheros Naranjo, D. A., Senior, J. L., & Higginbotham,
A. P. (2025). Dual relaxation oscillations in a Josephson-junction array. Physical
Review Applied. American Physical Society. https://doi.org/10.1103/qvls-7s3q
chicago: Mukhopadhyay, Soham, Diego A Lancheros Naranjo, Jorden L Senior, and Andrew
P Higginbotham. “Dual Relaxation Oscillations in a Josephson-Junction Array.”
Physical Review Applied. American Physical Society, 2025. https://doi.org/10.1103/qvls-7s3q.
ieee: S. Mukhopadhyay, D. A. Lancheros Naranjo, J. L. Senior, and A. P. Higginbotham,
“Dual relaxation oscillations in a Josephson-junction array,” Physical Review
Applied, vol. 24. American Physical Society, 2025.
ista: Mukhopadhyay S, Lancheros Naranjo DA, Senior JL, Higginbotham AP. 2025. Dual
relaxation oscillations in a Josephson-junction array. Physical Review Applied.
24, 014035.
mla: Mukhopadhyay, Soham, et al. “Dual Relaxation Oscillations in a Josephson-Junction
Array.” Physical Review Applied, vol. 24, 014035, American Physical Society,
2025, doi:10.1103/qvls-7s3q.
short: S. Mukhopadhyay, D.A. Lancheros Naranjo, J.L. Senior, A.P. Higginbotham,
Physical Review Applied 24 (2025).
corr_author: '1'
date_created: 2025-09-10T05:41:30Z
date_published: 2025-07-17T00:00:00Z
date_updated: 2026-06-03T07:16:04Z
day: '17'
ddc:
- '530'
department:
- _id: GradSch
- _id: AnHi
doi: 10.1103/qvls-7s3q
ec_funded: 1
external_id:
arxiv:
- '2408.07829 '
isi:
- '001537333100001'
file:
- access_level: open_access
checksum: 6cc3c9beeb7c0a88ee0a072c9a32b78b
content_type: application/pdf
creator: dernst
date_created: 2025-09-10T07:29:06Z
date_updated: 2025-09-10T07:29:06Z
file_id: '20335'
file_name: 2025_PhysReviewAppl_Mukhopadhyay.pdf
file_size: 1370466
relation: main_file
success: 1
file_date_updated: 2025-09-10T07:29:06Z
has_accepted_license: '1'
intvolume: ' 24'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 0aa3608a-070f-11eb-9043-e9cd8a2bd931
grant_number: P33692
name: Cavity electromechanics across a quantum phase transition
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: eb9b30ac-77a9-11ec-83b8-871f581d53d2
name: Protected states of quantum matter
publication: Physical Review Applied
publication_identifier:
issn:
- 2331-7019
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
record:
- id: '18057'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Dual relaxation oscillations in a Josephson-junction array
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2025'
...
---
_id: '13271'
abstract:
- lang: eng
text: "In this paper, we prove the convexity of trace functionals (A,B,C)↦Tr|BpACq|s,\r\nfor
parameters (p, q, s) that are best possible, where B and C are any n-by-n positive-definite
matrices, and A is any n-by-n matrix. We also obtain the monotonicity versions
of trace functionals of this type. As applications, we extend some results in
Carlen et al. (Linear Algebra Appl 490:174–185, 2016), Hiai and Petz (Publ Res
Inst Math Sci 48(3):525-542, 2012) and resolve a conjecture in Al-Rashed and Zegarliński
(Infin Dimens Anal Quantum Probab Relat Top 17(4):1450029, 2014) in the matrix
setting. Other conjectures in Al-Rashed and Zegarliński (Infin Dimens Anal Quantum
Probab Relat Top 17(4):1450029, 2014) will also be discussed. We also show that
some related trace functionals are not concave in general. Such concavity results
were expected to hold in different problems."
acknowledgement: I am grateful to Boguslaw Zegarliński for asking me the questions
in [3] and for helpful communication. I also want to thank Paata Ivanisvili for
drawing [25] to my attention and for useful correspondence. Many thanks to the anonymous
referee for the valuable comments and for pointing out some errors in an earlier
version of the paper. This work is partially supported by the European Union’s Horizon
2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement
No. 754411 and the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Haonan
full_name: Zhang, Haonan
id: D8F41E38-9E66-11E9-A9E2-65C2E5697425
last_name: Zhang
citation:
ama: Zhang H. Some convexity and monotonicity results of trace functionals. Annales
Henri Poincare. 2024;25:2087-2106. doi:10.1007/s00023-023-01345-7
apa: Zhang, H. (2024). Some convexity and monotonicity results of trace functionals.
Annales Henri Poincare. Springer Nature. https://doi.org/10.1007/s00023-023-01345-7
chicago: Zhang, Haonan. “Some Convexity and Monotonicity Results of Trace Functionals.”
Annales Henri Poincare. Springer Nature, 2024. https://doi.org/10.1007/s00023-023-01345-7.
ieee: H. Zhang, “Some convexity and monotonicity results of trace functionals,”
Annales Henri Poincare, vol. 25. Springer Nature, pp. 2087–2106, 2024.
ista: Zhang H. 2024. Some convexity and monotonicity results of trace functionals.
Annales Henri Poincare. 25, 2087–2106.
mla: Zhang, Haonan. “Some Convexity and Monotonicity Results of Trace Functionals.”
Annales Henri Poincare, vol. 25, Springer Nature, 2024, pp. 2087–106, doi:10.1007/s00023-023-01345-7.
short: H. Zhang, Annales Henri Poincare 25 (2024) 2087–2106.
corr_author: '1'
date_created: 2023-07-23T22:01:15Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-04-14T07:43:55Z
day: '01'
department:
- _id: JaMa
doi: 10.1007/s00023-023-01345-7
ec_funded: 1
external_id:
arxiv:
- '2108.05785'
isi:
- '001025709100001'
intvolume: ' 25'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2108.05785
month: '04'
oa: 1
oa_version: Preprint
page: 2087-2106
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: eb958bca-77a9-11ec-83b8-c565cb50d8d6
grant_number: M03337
name: Curvature-dimension in noncommutative analysis
publication: Annales Henri Poincare
publication_identifier:
issn:
- 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Some convexity and monotonicity results of trace functionals
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2024'
...
---
_id: '14451'
abstract:
- lang: eng
text: 'We investigate the potential of Multi-Objective, Deep Reinforcement Learning
for stock and cryptocurrency single-asset trading: in particular, we consider
a Multi-Objective algorithm which generalizes the reward functions and discount
factor (i.e., these components are not specified a priori, but incorporated in
the learning process). Firstly, using several important assets (BTCUSD, ETHUSDT,
XRPUSDT, AAPL, SPY, NIFTY50), we verify the reward generalization property of
the proposed Multi-Objective algorithm, and provide preliminary statistical evidence
showing increased predictive stability over the corresponding Single-Objective
strategy. Secondly, we show that the Multi-Objective algorithm has a clear edge
over the corresponding Single-Objective strategy when the reward mechanism is
sparse (i.e., when non-null feedback is infrequent over time). Finally, we discuss
the generalization properties with respect to the discount factor. The entirety
of our code is provided in open-source format.'
acknowledgement: Open access funding provided by Università degli Studi di Trieste
within the CRUI-CARE Agreement. Funding was provided by Austrian Science Fund (Grant
No. F65), Horizon 2020 (Grant No. 754411) and Österreichische Forschungsförderungsgesellschaft.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Federico
full_name: Cornalba, Federico
id: 2CEB641C-A400-11E9-A717-D712E6697425
last_name: Cornalba
orcid: 0000-0002-6269-5149
- first_name: Constantin
full_name: Disselkamp, Constantin
last_name: Disselkamp
- first_name: Davide
full_name: Scassola, Davide
last_name: Scassola
- first_name: Christopher
full_name: Helf, Christopher
last_name: Helf
citation:
ama: 'Cornalba F, Disselkamp C, Scassola D, Helf C. Multi-objective reward generalization:
Improving performance of Deep Reinforcement Learning for applications in single-asset
trading. Neural Computing and Applications. 2024;36(2):617-637. doi:10.1007/s00521-023-09033-7'
apa: 'Cornalba, F., Disselkamp, C., Scassola, D., & Helf, C. (2024). Multi-objective
reward generalization: Improving performance of Deep Reinforcement Learning for
applications in single-asset trading. Neural Computing and Applications.
Springer Nature. https://doi.org/10.1007/s00521-023-09033-7'
chicago: 'Cornalba, Federico, Constantin Disselkamp, Davide Scassola, and Christopher
Helf. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement
Learning for Applications in Single-Asset Trading.” Neural Computing and Applications.
Springer Nature, 2024. https://doi.org/10.1007/s00521-023-09033-7.'
ieee: 'F. Cornalba, C. Disselkamp, D. Scassola, and C. Helf, “Multi-objective reward
generalization: Improving performance of Deep Reinforcement Learning for applications
in single-asset trading,” Neural Computing and Applications, vol. 36, no.
2. Springer Nature, pp. 617–637, 2024.'
ista: 'Cornalba F, Disselkamp C, Scassola D, Helf C. 2024. Multi-objective reward
generalization: Improving performance of Deep Reinforcement Learning for applications
in single-asset trading. Neural Computing and Applications. 36(2), 617–637.'
mla: 'Cornalba, Federico, et al. “Multi-Objective Reward Generalization: Improving
Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.”
Neural Computing and Applications, vol. 36, no. 2, Springer Nature, 2024,
pp. 617–37, doi:10.1007/s00521-023-09033-7.'
short: F. Cornalba, C. Disselkamp, D. Scassola, C. Helf, Neural Computing and Applications
36 (2024) 617–637.
corr_author: '1'
date_created: 2023-10-22T22:01:16Z
date_published: 2024-01-01T00:00:00Z
date_updated: 2025-04-23T07:39:14Z
day: '01'
ddc:
- '000'
department:
- _id: JuFi
doi: 10.1007/s00521-023-09033-7
ec_funded: 1
external_id:
arxiv:
- '2203.04579'
pmid:
- '38187995'
file:
- access_level: open_access
checksum: 04573d8e74c6119b97c2ca0a984e19a1
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T08:08:54Z
date_updated: 2024-07-16T08:08:54Z
file_id: '17251'
file_name: 2024_NeuralCompApplications_Cornalba.pdf
file_size: 4412285
relation: main_file
success: 1
file_date_updated: 2024-07-16T08:08:54Z
has_accepted_license: '1'
intvolume: ' 36'
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 617-637
pmid: 1
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Neural Computing and Applications
publication_identifier:
eissn:
- 1433-3058
issn:
- 0941-0643
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Multi-objective reward generalization: Improving performance of Deep Reinforcement
Learning for applications in single-asset trading'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2024'
...
---
_id: '14683'
abstract:
- lang: eng
text: "Mosaic analysis with double markers (MADM) technology enables the generation
of genetic mosaic tissue in mice and high-resolution phenotyping at the individual
cell level. Here, we present a protocol for isolating MADM-labeled cells with
high yield for downstream molecular analyses using fluorescence-activated cell
sorting (FACS). We describe steps for generating MADM-labeled mice, perfusion,
single-cell suspension, and debris removal. We then detail procedures for cell
sorting by FACS and downstream analysis. This protocol is suitable for embryonic
to adult mice.\r\nFor complete details on the use and execution of this protocol,
please refer to Contreras et al. (2021).1"
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: This research was supported by the Scientific Service Units (SSU)
at IST Austria through resources provided by the Imaging & Optics Facility (IOF)
and Preclinical Facilities (PCF). N.A. received support from FWF Firnberg-Programme
(T 1031). G.C. received support from the European Union’s Horizon 2020 research
and innovation programme under the Marie Skłodowska-Curie grant agreement no. 754411
as an ISTplus postdoctoral fellow. This work was also supported by IST Austria institutional
funds, FWF SFB F78 to S.H., and the European Research Council (ERC) under the European
Union’s Horizon 2020 research and innovation programme (grant agreement no. 725780
LinPro) to S.H.
article_number: '102771'
article_processing_charge: Yes (in subscription journal)
article_type: review
author:
- first_name: Nicole
full_name: Amberg, Nicole
id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
last_name: Amberg
orcid: 0000-0002-3183-8207
- first_name: Giselle T
full_name: Cheung, Giselle T
id: 471195F6-F248-11E8-B48F-1D18A9856A87
last_name: Cheung
orcid: 0000-0001-8457-2572
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Amberg N, Cheung GT, Hippenmeyer S. Protocol for sorting cells from mouse brains
labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols.
2024;5(1). doi:10.1016/j.xpro.2023.102771
apa: Amberg, N., Cheung, G. T., & Hippenmeyer, S. (2024). Protocol for sorting
cells from mouse brains labeled with mosaic analysis with double markers by flow
cytometry. STAR Protocols. Elsevier. https://doi.org/10.1016/j.xpro.2023.102771
chicago: Amberg, Nicole, Giselle T Cheung, and Simon Hippenmeyer. “Protocol for
Sorting Cells from Mouse Brains Labeled with Mosaic Analysis with Double Markers
by Flow Cytometry.” STAR Protocols. Elsevier, 2024. https://doi.org/10.1016/j.xpro.2023.102771.
ieee: N. Amberg, G. T. Cheung, and S. Hippenmeyer, “Protocol for sorting cells from
mouse brains labeled with mosaic analysis with double markers by flow cytometry,”
STAR Protocols, vol. 5, no. 1. Elsevier, 2024.
ista: Amberg N, Cheung GT, Hippenmeyer S. 2024. Protocol for sorting cells from
mouse brains labeled with mosaic analysis with double markers by flow cytometry.
STAR Protocols. 5(1), 102771.
mla: Amberg, Nicole, et al. “Protocol for Sorting Cells from Mouse Brains Labeled
with Mosaic Analysis with Double Markers by Flow Cytometry.” STAR Protocols,
vol. 5, no. 1, 102771, Elsevier, 2024, doi:10.1016/j.xpro.2023.102771.
short: N. Amberg, G.T. Cheung, S. Hippenmeyer, STAR Protocols 5 (2024).
corr_author: '1'
date_created: 2023-12-13T11:48:05Z
date_published: 2024-03-15T00:00:00Z
date_updated: 2025-04-15T08:23:06Z
day: '15'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.xpro.2023.102771
ec_funded: 1
external_id:
pmid:
- '38070137'
file:
- access_level: open_access
checksum: 3f0ee62e04bf5a44b45b035662826e95
content_type: application/pdf
creator: dernst
date_created: 2024-07-16T11:50:03Z
date_updated: 2024-07-16T11:50:03Z
file_id: '17260'
file_name: 2024_STARProtoc_Amberg.pdf
file_size: 8871807
relation: main_file
success: 1
file_date_updated: 2024-07-16T11:50:03Z
has_accepted_license: '1'
intvolume: ' 5'
issue: '1'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Neuroscience
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 268F8446-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: T01031
name: Role of Eed in neural stem cell lineage progression
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
grant_number: F7805
name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
Mechanisms of Neural Stem Cell Lineage Progression
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: STAR Protocols
publication_identifier:
issn:
- 2666-1667
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Protocol for sorting cells from mouse brains labeled with mosaic analysis with
double markers by flow cytometry
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
OA_place: repository
OA_type: green
_id: '14845'
abstract:
- lang: eng
text: We study a linear rotor in a bosonic bath within the angulon formalism. Our
focus is on systems where isotropic or anisotropic impurity-boson interactions
support a shallow bound state. To study the fate of the angulon in the vicinity
of bound-state formation, we formulate a beyond-linear-coupling angulon Hamiltonian.
First, we use it to study attractive, spherically symmetric impurity-boson interactions
for which the linear rotor can be mapped onto a static impurity. The well-known
polaron formalism provides an adequate description in this limit. Second, we consider
anisotropic potentials, and show that the presence of a shallow bound state with
pronounced anisotropic character leads to a many-body instability that washes
out the angulon dynamics.
acknowledgement: "We would like to thank G. Bighin, I. Cherepanov, E. Paerschke, and
E. Yakaboylu for insightful discussions on a wide range of topics. This work has
been supported by the European Research Council (ERC) Starting Grant No. 801770
(ANGULON). A.G. and A.G.V. acknowledge support from the European Union’s Horizon
2020 research and innovation\r\nprogram under the Marie Skłodowska-Curie Grant Agreement
No. 754411. Numerical calculations were performed on the Euler cluster managed by
the HPC team at ETH Zurich.\r\nR.S. acknowledges support by the Deutsche Forschungsgemeinschaft
under Germany’s Excellence Strategy Grant No. EXC 2181/1-390900948 (the Heidelberg
STRUCTURES Excellence Cluster). T.D. acknowledges support from the Isaac Newton
Studentship and the Science and Technology Facilities Council under Grant No. ST/V50659X/1."
article_number: '014102'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Tibor
full_name: Dome, Tibor
id: 7e3293e2-b9dc-11ee-97a9-cd73400f6994
last_name: Dome
orcid: 0000-0003-2586-3702
- first_name: Artem
full_name: Volosniev, Artem
id: 37D278BC-F248-11E8-B48F-1D18A9856A87
last_name: Volosniev
orcid: 0000-0003-0393-5525
- first_name: Areg
full_name: Ghazaryan, Areg
id: 4AF46FD6-F248-11E8-B48F-1D18A9856A87
last_name: Ghazaryan
orcid: 0000-0001-9666-3543
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: Richard
full_name: Schmidt, Richard
last_name: Schmidt
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
citation:
ama: Dome T, Volosniev A, Ghazaryan A, Safari L, Schmidt R, Lemeshko M. Linear rotor
in an ideal Bose gas near the threshold for binding. Physical Review B.
2024;109(1). doi:10.1103/PhysRevB.109.014102
apa: Dome, T., Volosniev, A., Ghazaryan, A., Safari, L., Schmidt, R., & Lemeshko,
M. (2024). Linear rotor in an ideal Bose gas near the threshold for binding. Physical
Review B. American Physical Society. https://doi.org/10.1103/PhysRevB.109.014102
chicago: Dome, Tibor, Artem Volosniev, Areg Ghazaryan, Laleh Safari, Richard Schmidt,
and Mikhail Lemeshko. “Linear Rotor in an Ideal Bose Gas near the Threshold for
Binding.” Physical Review B. American Physical Society, 2024. https://doi.org/10.1103/PhysRevB.109.014102.
ieee: T. Dome, A. Volosniev, A. Ghazaryan, L. Safari, R. Schmidt, and M. Lemeshko,
“Linear rotor in an ideal Bose gas near the threshold for binding,” Physical
Review B, vol. 109, no. 1. American Physical Society, 2024.
ista: Dome T, Volosniev A, Ghazaryan A, Safari L, Schmidt R, Lemeshko M. 2024. Linear
rotor in an ideal Bose gas near the threshold for binding. Physical Review B.
109(1), 014102.
mla: Dome, Tibor, et al. “Linear Rotor in an Ideal Bose Gas near the Threshold for
Binding.” Physical Review B, vol. 109, no. 1, 014102, American Physical
Society, 2024, doi:10.1103/PhysRevB.109.014102.
short: T. Dome, A. Volosniev, A. Ghazaryan, L. Safari, R. Schmidt, M. Lemeshko,
Physical Review B 109 (2024).
corr_author: '1'
date_created: 2024-01-21T23:00:57Z
date_published: 2024-01-01T00:00:00Z
date_updated: 2025-09-04T11:49:14Z
day: '01'
department:
- _id: MiLe
doi: 10.1103/PhysRevB.109.014102
ec_funded: 1
external_id:
arxiv:
- '2308.03852'
isi:
- '001172754500002'
intvolume: ' 109'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2308.03852
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '801770'
name: 'Angulon: physics and applications of a new quasiparticle'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Physical Review B
publication_identifier:
eissn:
- 2469-9969
issn:
- 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Linear rotor in an ideal Bose gas near the threshold for binding
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 109
year: '2024'
...
---
APC_amount: 3041,76 EUR
OA_place: publisher
OA_type: hybrid
_id: '15083'
abstract:
- lang: eng
text: 'Direct reciprocity is a powerful mechanism for cooperation in social dilemmas.
The very logic of reciprocity, however, seems to require that individuals are
symmetric, and that everyone has the same means to influence each others’ payoffs.
Yet in many applications, individuals are asymmetric. Herein, we study the effect
of asymmetry in linear public good games. Individuals may differ in their endowments
(their ability to contribute to a public good) and in their productivities (how
effective their contributions are). Given the individuals’ productivities, we
ask which allocation of endowments is optimal for cooperation. To this end, we
consider two notions of optimality. The first notion focuses on the resilience
of cooperation. The respective endowment distribution ensures that full cooperation
is feasible even under the most adverse conditions. The second notion focuses
on efficiency. The corresponding endowment distribution maximizes group welfare.
Using analytical methods, we fully characterize these two endowment distributions.
This analysis reveals that both optimality notions favor some endowment inequality:
More productive players ought to get higher endowments. Yet the two notions disagree
on how unequal endowments are supposed to be. A focus on resilience results in
less inequality. With additional simulations, we show that the optimal endowment
allocation needs to account for both the resilience and the efficiency of cooperation.'
acknowledgement: 'This work was supported by the European Research Council CoG 863818
(ForM-SMArt) (to K.C.) and the European Research Council Starting Grant 850529:
E-DIRECT (to C.H.), the European Union’s Horizon 2020 research and innovation program
under the Marie Skłodowska-Curie Grant Agreement #754411 and the French Agence Nationale
de la Recherche (under the Investissement d’Avenir Programme, ANR-17-EURE-0010)
(to M.K.).'
article_number: e2315558121
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Valentin
full_name: Hübner, Valentin
id: 2c8aa207-dc7d-11ea-9b2f-f22972ecd910
last_name: Hübner
orcid: 0009-0001-5009-4987
- first_name: Manuel
full_name: Staab, Manuel
last_name: Staab
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Maria
full_name: Kleshnina, Maria
last_name: Kleshnina
citation:
ama: Hübner V, Staab M, Hilbe C, Chatterjee K, Kleshnina M. Efficiency and resilience
of cooperation in asymmetric social dilemmas. Proceedings of the National Academy
of Sciences of the United States of America. 2024;121(10). doi:10.1073/pnas.2315558121
apa: Hübner, V., Staab, M., Hilbe, C., Chatterjee, K., & Kleshnina, M. (2024).
Efficiency and resilience of cooperation in asymmetric social dilemmas. Proceedings
of the National Academy of Sciences of the United States of America. National
Academy of Sciences. https://doi.org/10.1073/pnas.2315558121
chicago: Hübner, Valentin, Manuel Staab, Christian Hilbe, Krishnendu Chatterjee,
and Maria Kleshnina. “Efficiency and Resilience of Cooperation in Asymmetric Social
Dilemmas.” Proceedings of the National Academy of Sciences of the United States
of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2315558121.
ieee: V. Hübner, M. Staab, C. Hilbe, K. Chatterjee, and M. Kleshnina, “Efficiency
and resilience of cooperation in asymmetric social dilemmas,” Proceedings of
the National Academy of Sciences of the United States of America, vol. 121,
no. 10. National Academy of Sciences, 2024.
ista: Hübner V, Staab M, Hilbe C, Chatterjee K, Kleshnina M. 2024. Efficiency and
resilience of cooperation in asymmetric social dilemmas. Proceedings of the National
Academy of Sciences of the United States of America. 121(10), e2315558121.
mla: Hübner, Valentin, et al. “Efficiency and Resilience of Cooperation in Asymmetric
Social Dilemmas.” Proceedings of the National Academy of Sciences of the United
States of America, vol. 121, no. 10, e2315558121, National Academy of Sciences,
2024, doi:10.1073/pnas.2315558121.
short: V. Hübner, M. Staab, C. Hilbe, K. Chatterjee, M. Kleshnina, Proceedings of
the National Academy of Sciences of the United States of America 121 (2024).
corr_author: '1'
date_created: 2024-03-05T09:18:49Z
date_published: 2024-03-05T00:00:00Z
date_updated: 2026-04-07T12:30:56Z
day: '05'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1073/pnas.2315558121
ec_funded: 1
external_id:
isi:
- '001207786500004'
pmid:
- '38408249'
file:
- access_level: open_access
checksum: 068520e3efd4d008bb9177e8aedb7d22
content_type: application/pdf
creator: dernst
date_created: 2024-03-12T13:12:22Z
date_updated: 2024-03-12T13:12:22Z
file_id: '15109'
file_name: 2024_PNAS_Huebner.pdf
file_size: 2203220
relation: main_file
success: 1
file_date_updated: 2024-03-12T13:12:22Z
has_accepted_license: '1'
intvolume: ' 121'
isi: 1
issue: '10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the National Academy of Sciences of the United States
of America
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
link:
- description: News on ISTA Website
relation: press_release
url: https://ista.ac.at/en/news/what-math-tells-us-about-social-dilemmas/
record:
- id: '15108'
relation: research_data
status: public
- id: '19903'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Efficiency and resilience of cooperation in asymmetric social dilemmas
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 121
year: '2024'
...
---
_id: '15317'
abstract:
- lang: eng
text: 'We consider the open symmetric exclusion (SEP) and inclusion (SIP) processes
on a bounded Lipschitz domain Ω, with both fast and slow boundary. For the random
walks on Ω dual to SEP/SIP we establish: a functional-CLT-type convergence to
the Brownian motion on Ω with either Neumann (slow boundary), Dirichlet (fast
boundary), or Robin (at criticality) boundary conditions; the discrete-to-continuum
convergence of the corresponding harmonic profiles. As a consequence, we rigorously
derive the hydrodynamic and hydrostatic limits for SEP/SIP on Ω, and analyze their
stationary nonequilibrium fluctuations. All scaling limit results for SEP/SIP
concern finite-dimensional distribution convergence only, as our duality techniques
do not require to establish tightness for the fields associated to the particle
systems.'
acknowledgement: "The first author gratefully acknowledges funding by the Austrian
Science Fund (FWF) grant F65, by the European Research Council (ERC, grant agreement
No 716117, awarded to Prof. Dr. Jan Maas). He also gratefully acknowledges funding
of his current position by the Austrian Science Fund (FWF) grant ESPRIT 208.\r\nThe
second author gratefully acknowledges funding by the Hausdorff Center for Mathematics
at the University of Bonn. Part of this work was completed while this author was
a member of the Institute of Science and Technology Austria. He gratefully acknowledges
funding of his position at that time by the Austrian Science Fund (FWF) grants F65
and W1245.\r\nThe third author gratefully acknowledges funding by the Lise Meitner
fellowship, Austrian Science Fund (FWF): M3211. Part of this work was completed
while funded by the European Union’s Horizon 2020 research and innovation programme
under the Marie-Skłodowska-Curie grant agreement No. 754411."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Lorenzo
full_name: Dello Schiavo, Lorenzo
id: ECEBF480-9E4F-11EA-B557-B0823DDC885E
last_name: Dello Schiavo
orcid: 0000-0002-9881-6870
- first_name: Lorenzo
full_name: Portinale, Lorenzo
id: 30AD2CBC-F248-11E8-B48F-1D18A9856A87
last_name: Portinale
- first_name: Federico
full_name: Sau, Federico
id: E1836206-9F16-11E9-8814-AEFDE5697425
last_name: Sau
citation:
ama: Dello Schiavo L, Portinale L, Sau F. Scaling limits of random walks, harmonic
profiles, and stationary nonequilibrium states in Lipschitz domains. Annals
of Applied Probability. 2024;34(2):1789-1845. doi:10.1214/23-AAP2007
apa: Dello Schiavo, L., Portinale, L., & Sau, F. (2024). Scaling limits of random
walks, harmonic profiles, and stationary nonequilibrium states in Lipschitz domains.
Annals of Applied Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/23-AAP2007
chicago: Dello Schiavo, Lorenzo, Lorenzo Portinale, and Federico Sau. “Scaling Limits
of Random Walks, Harmonic Profiles, and Stationary Nonequilibrium States in Lipschitz
Domains.” Annals of Applied Probability. Institute of Mathematical Statistics,
2024. https://doi.org/10.1214/23-AAP2007.
ieee: L. Dello Schiavo, L. Portinale, and F. Sau, “Scaling limits of random walks,
harmonic profiles, and stationary nonequilibrium states in Lipschitz domains,”
Annals of Applied Probability, vol. 34, no. 2. Institute of Mathematical
Statistics, pp. 1789–1845, 2024.
ista: Dello Schiavo L, Portinale L, Sau F. 2024. Scaling limits of random walks,
harmonic profiles, and stationary nonequilibrium states in Lipschitz domains.
Annals of Applied Probability. 34(2), 1789–1845.
mla: Dello Schiavo, Lorenzo, et al. “Scaling Limits of Random Walks, Harmonic Profiles,
and Stationary Nonequilibrium States in Lipschitz Domains.” Annals of Applied
Probability, vol. 34, no. 2, Institute of Mathematical Statistics, 2024, pp.
1789–845, doi:10.1214/23-AAP2007.
short: L. Dello Schiavo, L. Portinale, F. Sau, Annals of Applied Probability 34
(2024) 1789–1845.
corr_author: '1'
date_created: 2024-04-14T22:01:02Z
date_published: 2024-04-01T00:00:00Z
date_updated: 2025-09-04T13:36:00Z
day: '01'
department:
- _id: JaMa
doi: 10.1214/23-AAP2007
ec_funded: 1
external_id:
arxiv:
- '2112.14196'
isi:
- '001198623200016'
intvolume: ' 34'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2112.14196
month: '04'
oa: 1
oa_version: Preprint
page: 1789-1845
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
grant_number: F6504
name: Taming Complexity in Partial Differential Systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 3490b268-11ca-11ed-8bc3-e0ad03f48839
grant_number: M03211
name: Reaching consensus in heterogeneous random opinion dynamics
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c
grant_number: E208
name: Configuration Spaces over Non-Smooth Spaces
- _id: 260788DE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: W1245
name: Dissipation and dispersion in nonlinear partial differential equations
publication: Annals of Applied Probability
publication_identifier:
issn:
- 1050-5164
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scaling limits of random walks, harmonic profiles, and stationary nonequilibrium
states in Lipschitz domains
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 34
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '17052'
abstract:
- lang: eng
text: Production of thermoelectric materials from solution-processed particles involves
the synthesis of particles, their purification and densification into pelletized
material. Chemical changes that occur during each one of these steps render them
performance determining. Particularly the purification steps, bypassed in conventional
solid-state synthesis, are the cause for large discrepancies among similar solution-processed
materials. In present work, the investigation focuses on a water-based surfactant
free solution synthesis of SnSe, a highly relevant thermoelectric material. We
show and rationalize that the number of leaching steps, purification solvent,
annealing, and annealing atmosphere have significant influence on the Sn : Se
ratio and impurity content in the powder. Such compositional changes that are
undetectable by conventional characterization techniques lead to distinct consolidated
materials with different types and concentration of defects. Additionally, the
profound effect on their transport properties is demonstrated. We emphasize that
understanding the chemistry and identifying key chemical species and their role
throughout the process is paramount for optimizing material performance. Furthermore,
we aim to demonstrate the necessity of comprehensive reporting of these steps
as a standard practice to ensure material reproducibility.
acknowledged_ssus:
- _id: EM-Fac
- _id: NMR
- _id: LifeSc
acknowledgement: ISTA and the Werner Siemens Foundation financially supported this
work. The Scientific Service Units (SSU) of ISTA supported this research through
resources provided by the Electron Microscopy Facility (EMF), NMR Facility and the
Lab Support Facility (LSF). Dr. Krishnendu Maji at ISTA aided in this work through
XRD analysis of the crystal phase of SnSe. Y.L. acknowledges funding from the European
Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie
grant agreement No. 754411, the National Natural Science Foundation of China (NSFC)
(Grants No. 22209034). M.C. received funding from the European Union's Horizon 2020
research and innovation program under the Marie Skłodowska-Curie Grant Agreement
No. 665385.
article_number: e202402628
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Christine
full_name: Fiedler, Christine
id: bd3fceba-dc74-11ea-a0a7-c17f71817366
last_name: Fiedler
- first_name: Mariano
full_name: Calcabrini, Mariano
id: 45D7531A-F248-11E8-B48F-1D18A9856A87
last_name: Calcabrini
orcid: 0000-0003-4566-5877
- first_name: Yu
full_name: Liu, Yu
id: 2A70014E-F248-11E8-B48F-1D18A9856A87
last_name: Liu
orcid: 0000-0001-7313-6740
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
citation:
ama: Fiedler C, Calcabrini M, Liu Y, Ibáñez M. Unveiling crucial chemical processing
parameters influencing the performance of solution-processed inorganic thermoelectric
materials. Angewandte Chemie - International Edition. 2024;63(25). doi:10.1002/anie.202402628
apa: Fiedler, C., Calcabrini, M., Liu, Y., & Ibáñez, M. (2024). Unveiling crucial
chemical processing parameters influencing the performance of solution-processed
inorganic thermoelectric materials. Angewandte Chemie - International Edition.
Wiley. https://doi.org/10.1002/anie.202402628
chicago: Fiedler, Christine, Mariano Calcabrini, Yu Liu, and Maria Ibáñez. “Unveiling
Crucial Chemical Processing Parameters Influencing the Performance of Solution-Processed
Inorganic Thermoelectric Materials.” Angewandte Chemie - International Edition.
Wiley, 2024. https://doi.org/10.1002/anie.202402628.
ieee: C. Fiedler, M. Calcabrini, Y. Liu, and M. Ibáñez, “Unveiling crucial chemical
processing parameters influencing the performance of solution-processed inorganic
thermoelectric materials,” Angewandte Chemie - International Edition, vol.
63, no. 25. Wiley, 2024.
ista: Fiedler C, Calcabrini M, Liu Y, Ibáñez M. 2024. Unveiling crucial chemical
processing parameters influencing the performance of solution-processed inorganic
thermoelectric materials. Angewandte Chemie - International Edition. 63(25), e202402628.
mla: Fiedler, Christine, et al. “Unveiling Crucial Chemical Processing Parameters
Influencing the Performance of Solution-Processed Inorganic Thermoelectric Materials.”
Angewandte Chemie - International Edition, vol. 63, no. 25, e202402628,
Wiley, 2024, doi:10.1002/anie.202402628.
short: C. Fiedler, M. Calcabrini, Y. Liu, M. Ibáñez, Angewandte Chemie - International
Edition 63 (2024).
corr_author: '1'
date_created: 2024-05-26T22:00:58Z
date_published: 2024-06-17T00:00:00Z
date_updated: 2025-09-08T07:36:36Z
day: '17'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1002/anie.202402628
ec_funded: 1
external_id:
isi:
- '001223768400001'
pmid:
- '38623865'
file:
- access_level: open_access
checksum: 1572a0f4d2df55751761efeb2d11c7fc
content_type: application/pdf
creator: dernst
date_created: 2025-01-09T09:12:07Z
date_updated: 2025-01-09T09:12:07Z
file_id: '18797'
file_name: 2024_AngewChemieIntern_Fiedler.pdf
file_size: 16347226
relation: main_file
success: 1
file_date_updated: 2025-01-09T09:12:07Z
has_accepted_license: '1'
intvolume: ' 63'
isi: 1
issue: '25'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Angewandte Chemie - International Edition
publication_identifier:
eissn:
- 1521-3773
issn:
- 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unveiling crucial chemical processing parameters influencing the performance
of solution-processed inorganic thermoelectric materials
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 63
year: '2024'
...