[{"article_processing_charge":"No","abstract":[{"text":"Topological simplification is the process of reducing complexity of a function while maintaining its essential features. Its goal is to find a new filter function, which reorders cells of the input complex in a way which eliminates some persistent homological features, without affecting the rest. We present a new approach to simplification based on the concept of forbidden regions and combinatorial dynamics. It allows us to reorder and cancel critical values, whose cancellation is not possible using existing methods because they are not consecutive in the total order. Each such cancellation takes O(c⋅n) time in the worst case, where c is the number of birth-death pairs and n is the size of the input complex.","lang":"eng"}],"department":[{"_id":"HeEd"}],"doi":"10.4230/LIPIcs.SoCG.2026.72","author":[{"first_name":"Jakub","last_name":"Leśkiewicz","full_name":"Leśkiewicz, Jakub"},{"first_name":"Bartosz","last_name":"Furmanek","full_name":"Furmanek, Bartosz"},{"last_name":"Lipiński","id":"dfffb474-4317-11ee-8f5c-fe3fc95a425e","orcid":"0000-0001-9789-9750","first_name":"Michał","full_name":"Lipiński, Michał"},{"full_name":"Morozov, Dmitriy","last_name":"Morozov","first_name":"Dmitriy"}],"_id":"22002","ddc":["500"],"oa":1,"has_accepted_license":"1","intvolume":"       367","das_tickbox":"0","language":[{"iso":"eng"}],"external_id":{"arxiv":["2603.16416"]},"file_date_updated":"2026-06-22T07:39:21Z","file":[{"access_level":"open_access","date_updated":"2026-06-22T07:39:21Z","file_size":2052749,"checksum":"3be91c06fdf716c8735b6af64a09a921","date_created":"2026-06-22T07:39:21Z","content_type":"application/pdf","creator":"dernst","file_id":"22110","success":1,"file_name":"2026_LIPIcSSoCG_Leskiewicz.pdf","relation":"main_file"}],"date_updated":"2026-06-22T07:45:36Z","fulldoi":"https://doi.org/10.4230/LIPIcs.SoCG.2026.72","keyword":["persistent homology","topological simplification","depth posets"],"alternative_title":["LIPIcs"],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","month":"05","year":"2026","volume":367,"date_published":"2026-05-27T00:00:00Z","ec_funded":1,"oa_version":"Published Version","article_number":"72:1-72:17","title":"Topological simplification guided by forbidden regions","conference":{"name":"SoCG: Symposium on Computational Geometry","start_date":"2026-06-02","location":"New Brunswick, NJ, United States","end_date":"2026-06-05"},"quality_controlled":"1","publication_identifier":{"eissn":["1868-8969"],"isbn":["9783959774185"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"42nd International Symposium on Computational Geometry","status":"public","OA_place":"publisher","OA_type":"gold","citation":{"mla":"Leśkiewicz, Jakub, et al. “Topological Simplification Guided by Forbidden Regions.” <i>42nd International Symposium on Computational Geometry</i>, vol. 367, 72:1-72:17, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.72\">10.4230/LIPIcs.SoCG.2026.72</a>.","chicago":"Leśkiewicz, Jakub, Bartosz Furmanek, Michał Lipiński, and Dmitriy Morozov. “Topological Simplification Guided by Forbidden Regions.” In <i>42nd International Symposium on Computational Geometry</i>, Vol. 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.72\">https://doi.org/10.4230/LIPIcs.SoCG.2026.72</a>.","ama":"Leśkiewicz J, Furmanek B, Lipiński M, Morozov D. Topological simplification guided by forbidden regions. In: <i>42nd International Symposium on Computational Geometry</i>. Vol 367. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2026. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.72\">10.4230/LIPIcs.SoCG.2026.72</a>","ista":"Leśkiewicz J, Furmanek B, Lipiński M, Morozov D. 2026. Topological simplification guided by forbidden regions. 42nd International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 367, 72:1-72:17.","ieee":"J. Leśkiewicz, B. Furmanek, M. Lipiński, and D. Morozov, “Topological simplification guided by forbidden regions,” in <i>42nd International Symposium on Computational Geometry</i>, New Brunswick, NJ, United States, 2026, vol. 367.","apa":"Leśkiewicz, J., Furmanek, B., Lipiński, M., &#38; Morozov, D. (2026). Topological simplification guided by forbidden regions. In <i>42nd International Symposium on Computational Geometry</i> (Vol. 367). New Brunswick, NJ, United States: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2026.72\">https://doi.org/10.4230/LIPIcs.SoCG.2026.72</a>","short":"J. Leśkiewicz, B. Furmanek, M. Lipiński, D. Morozov, in:, 42nd International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2026."},"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"acknowledgement":"Jakub Leśkiewicz wants to thank his supervisor, Prof. Marian Mrozek, forscientific guidance, patience, and opportunity to delay the rest of his duties while writing this work.\r\nThe author also extends thanks to his entire family, to Zuzanna Świątek, and to Mikołaj Kardyś,\r\nBEng, MSc, for providing meals during the most intensive periods of work. Jakub Leśkiewicz: The research was partially funded by the Polish National Science Center under Opus Grant No. 2019/35/B/ST1/00874 and Opus Grant 2025/57/B/ST1/00550. Bartosz Furmanek: The research was partially funded by the Polish National Science Center under Opus Grant No. 2019/35/B/ST1/00874 and Opus Grant 2025/57/B/ST1/00550. Michał Lipiński: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413. \r\nDmitriy Morozov: This work was supported in part by the U.S. Department of Energy, Office\r\nof Science, Office of Advanced Scientific Computing Research, under Contract No. DE-AC02-\r\n05CH11231.","license":"https://creativecommons.org/licenses/by/4.0/","type":"conference","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"day":"27","date_created":"2026-06-14T22:01:43Z","scopus_import":"1","arxiv":1,"corr_author":"1"},{"acknowledgement":"We thank N. Petridou (EMBL) for sharing results before publication. N.M. was supported by funding from the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie COFUND Actions ISTplus grant agreement number 754411. Y.I.L. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. The research was supported by funding to C.-P.H. from the NOMIS Foundation, Project ID 1.844. We would like to thank past and present members of the Heisenberg and Hannezo groups for discussions, particularly S. Shamipour, V. Doddihal, M. Jovic, N. Hino, F. N. Arslan, R. Kobylinska and C. Camelo for feedback on the draft manuscript. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria through resources provided by the Aquatics Facility, Imaging & Optics Facility (IOF), Scientific Computing (SciComp) facility and Lab Support Facility (LSF). Open access funding provided by Institute of Science and Technology (IST Austria).","related_material":{"link":[{"description":"News on ISTA website","relation":"research_data","url":"https://ista.ac.at/en/news/geometry-shapes-life/"}]},"citation":{"short":"N. Mishra, Y.I. Li, E.B. Hannezo, C.-P.J. Heisenberg, Nature Physics 22 (2026) 139–150.","apa":"Mishra, N., Li, Y. I., Hannezo, E. B., &#38; Heisenberg, C.-P. J. (2026). Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03122-1\">https://doi.org/10.1038/s41567-025-03122-1</a>","ieee":"N. Mishra, Y. I. Li, E. B. Hannezo, and C.-P. J. Heisenberg, “Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 139–150, 2026.","ista":"Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. 2026. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. Nature Physics. 22, 139–150.","ama":"Mishra N, Li YI, Hannezo EB, Heisenberg C-PJ. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. <i>Nature Physics</i>. 2026;22:139-150. doi:<a href=\"https://doi.org/10.1038/s41567-025-03122-1\">10.1038/s41567-025-03122-1</a>","chicago":"Mishra, Nikhil, Yuting I Li, Edouard B Hannezo, and Carl-Philipp J Heisenberg. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03122-1\">https://doi.org/10.1038/s41567-025-03122-1</a>.","mla":"Mishra, Nikhil, et al. “Geometry-Driven Asymmetric Cell Divisions Pattern Cell Cycles and Zygotic Genome Activation in the Zebrafish Embryo.” <i>Nature Physics</i>, vol. 22, Springer Nature, 2026, pp. 139–50, doi:<a href=\"https://doi.org/10.1038/s41567-025-03122-1\">10.1038/s41567-025-03122-1</a>."},"project":[{"call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"},{"_id":"917c023a-16d5-11f0-9cad-eb5cafc52090","name":"Cytoplasmic self-organization into cell-like compartments as a common guiding principle in early animal development"}],"oaworkid":1,"scopus_import":"1","date_created":"2026-01-20T10:12:19Z","day":"05","article_type":"original","corr_author":"1","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"quality_controlled":"1","PlanS_conform":"1","date_published":"2026-01-05T00:00:00Z","ec_funded":1,"title":"Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo","oa_version":"Published Version","publication":"Nature Physics","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publication_status":"published","status":"public","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"OA_place":"publisher","OA_type":"hybrid","publication_identifier":{"issn":["1745-2473"],"issnl":[" 1745-2473"],"eissn":["1745-2481"]},"date_updated":"2026-04-28T12:55:30Z","file_date_updated":"2026-01-21T08:21:11Z","file":[{"file_size":7335694,"checksum":"0ab7ac2fbcb61a364dba57152db64ed7","date_updated":"2026-01-21T08:21:11Z","access_level":"open_access","content_type":"application/pdf","creator":"dernst","file_id":"21026","success":1,"file_name":"2026_NaturePhysics_Mishra.pdf","relation":"main_file","date_created":"2026-01-21T08:21:11Z"}],"fulldoi":"https://doi.org/10.1038/s41567-025-03122-1","year":"2026","month":"01","publisher":"Springer Nature","volume":22,"author":[{"id":"C4D70E82-1081-11EA-B3ED-9A4C3DDC885E","first_name":"Nikhil","orcid":"0000-0002-6425-5788","last_name":"Mishra","full_name":"Mishra, Nikhil"},{"first_name":"Yuting I","id":"ee7a5ca8-8b71-11ed-b662-b3341c05b7eb","last_name":"Li","full_name":"Li, Yuting I"},{"last_name":"Hannezo","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B"},{"orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J"}],"page":"139-150","article_processing_charge":"Yes (via OA deal)","department":[{"_id":"EdHa"},{"_id":"CaHe"}],"abstract":[{"text":"Early embryo geometry is one of the most invariant species-specific traits, yet its role in ensuring developmental reproducibility and robustness remains underexplored. Here we show that in zebrafish, the geometry of the fertilized egg—specifically its curvature and volume—serves as a critical initial condition triggering a cascade of events that influence development. The embryo geometry guides patterned asymmetric cell divisions in the blastoderm, generating radial gradients of cell volume and nucleocytoplasmic ratio. These gradients generate mitotic phase waves, with the nucleocytoplasmic ratio determining individual cell cycle periods independently of other cells. We demonstrate that reducing cell autonomy reshapes these waves, emphasizing the instructive role of geometry-derived volume patterns in setting the intrinsic period of the cell cycle oscillator. In addition to organizing cell cycles, early embryo geometry spatially patterns zygotic genome activation at the midblastula transition, a key step in establishing embryonic autonomy. Disrupting the embryo shape alters the zygotic genome activation pattern and causes ectopic germ layer specification, underscoring the developmental significance of geometry. Together, our findings reveal a symmetry-breaking function of early embryo geometry in coordinating cell cycle and transcriptional patterning.","lang":"eng"}],"doi":"10.1038/s41567-025-03122-1","ddc":["570"],"has_accepted_license":"1","oa":1,"intvolume":"        22","language":[{"iso":"eng"}],"external_id":{"oaworkid":["W7118187193"]},"_id":"21015"},{"fulldoi":"https://doi.org/10.1007/s44007-025-00180-y","volume":5,"publisher":"Springer Nature","month":"01","year":"2026","date_updated":"2026-01-21T07:48:28Z","file_date_updated":"2026-01-21T07:45:03Z","file":[{"creator":"dernst","file_id":"21025","content_type":"application/pdf","file_name":"2026_LaMatematica_Brigati.pdf","relation":"main_file","success":1,"date_created":"2026-01-21T07:45:03Z","file_size":4992025,"checksum":"0702d8397f216555b1d5286e5d77f09c","date_updated":"2026-01-21T07:45:03Z","access_level":"open_access"}],"intvolume":"         5","has_accepted_license":"1","oa":1,"ddc":["510"],"external_id":{"arxiv":["2504.08658"]},"language":[{"iso":"eng"}],"_id":"21018","author":[{"full_name":"Brigati, Giovanni","last_name":"Brigati","first_name":"Giovanni","id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1"},{"full_name":"Dolbeault, Jean","first_name":"Jean","last_name":"Dolbeault"},{"last_name":"Simonov","first_name":"Nikita","full_name":"Simonov, Nikita"}],"abstract":[{"lang":"eng","text":"In this paper, we review recent results on stability and instability in logarithmic Sobolev inequalities, with a particular emphasis on strong norms. We consider several versions of these inequalities on the Euclidean space, for the Lebesgue and the Gaussian measures, and discuss their differences in terms of moments and stability. We give new and direct proofs, as well as examples and discuss the stability of a logarithmic uncertainty principle. Although we do not cover all aspects of the topic, we hope to contribute to establishing the state of the art."}],"department":[{"_id":"JaMa"}],"article_processing_charge":"Yes (via OA deal)","doi":"10.1007/s44007-025-00180-y","article_type":"original","arxiv":1,"date_created":"2026-01-20T10:14:55Z","day":"08","scopus_import":"1","corr_author":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","acknowledgement":"This work has been supported by the Project Conviviality (ANR-23-CE40–0003) of the French National Research Agency. G.B. has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. The authors thank a referee for a careful reading and suggestions which result in a significant improvement of the manuscript. Open access funding provided by Institute of Science and Technology (IST Austria). The work of GB has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. This work has been supported by the Project Conviviality (ANR-23-CE40–0003) of the French National Research Agency.","citation":{"short":"G. Brigati, J. Dolbeault, N. Simonov, La Matematica 5 (2026).","apa":"Brigati, G., Dolbeault, J., &#38; Simonov, N. (2026). Logarithmic Sobolev Inequalities: A review on stability and instability results. <i>La Matematica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s44007-025-00180-y\">https://doi.org/10.1007/s44007-025-00180-y</a>","ieee":"G. Brigati, J. Dolbeault, and N. Simonov, “Logarithmic Sobolev Inequalities: A review on stability and instability results,” <i>La Matematica</i>, vol. 5. Springer Nature, 2026.","ista":"Brigati G, Dolbeault J, Simonov N. 2026. Logarithmic Sobolev Inequalities: A review on stability and instability results. La Matematica. 5, 5.","ama":"Brigati G, Dolbeault J, Simonov N. Logarithmic Sobolev Inequalities: A review on stability and instability results. <i>La Matematica</i>. 2026;5. doi:<a href=\"https://doi.org/10.1007/s44007-025-00180-y\">10.1007/s44007-025-00180-y</a>","chicago":"Brigati, Giovanni, Jean Dolbeault, and Nikita Simonov. “Logarithmic Sobolev Inequalities: A Review on Stability and Instability Results.” <i>La Matematica</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s44007-025-00180-y\">https://doi.org/10.1007/s44007-025-00180-y</a>.","mla":"Brigati, Giovanni, et al. “Logarithmic Sobolev Inequalities: A Review on Stability and Instability Results.” <i>La Matematica</i>, vol. 5, 5, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s44007-025-00180-y\">10.1007/s44007-025-00180-y</a>."},"project":[{"call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"status":"public","publication":"La Matematica","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","OA_type":"hybrid","OA_place":"publisher","publication_identifier":{"issn":["2730-9657"]},"quality_controlled":"1","PlanS_conform":"1","date_published":"2026-01-08T00:00:00Z","title":"Logarithmic Sobolev Inequalities: A review on stability and instability results","oa_version":"Published Version","article_number":"5","ec_funded":1},{"type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"corr_author":"1","day":"09","date_created":"2026-02-17T08:17:53Z","article_type":"original","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"citation":{"ama":"Olmeda F, Gupta M, Bektas O, Rulands S. Spatiotemporal patterns of active epigenetic turnover. <i>PRX Life</i>. 2026;4. doi:<a href=\"https://doi.org/10.1103/89bj-79g5\">10.1103/89bj-79g5</a>","mla":"Olmeda, Fabrizio, et al. “Spatiotemporal Patterns of Active Epigenetic Turnover.” <i>PRX Life</i>, vol. 4, 013018, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/89bj-79g5\">10.1103/89bj-79g5</a>.","chicago":"Olmeda, Fabrizio, Misha Gupta, Onurcan Bektas, and Steffen Rulands. “Spatiotemporal Patterns of Active Epigenetic Turnover.” <i>PRX Life</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/89bj-79g5\">https://doi.org/10.1103/89bj-79g5</a>.","apa":"Olmeda, F., Gupta, M., Bektas, O., &#38; Rulands, S. (2026). Spatiotemporal patterns of active epigenetic turnover. <i>PRX Life</i>. American Physical Society. <a href=\"https://doi.org/10.1103/89bj-79g5\">https://doi.org/10.1103/89bj-79g5</a>","short":"F. Olmeda, M. Gupta, O. Bektas, S. Rulands, PRX Life 4 (2026).","ista":"Olmeda F, Gupta M, Bektas O, Rulands S. 2026. Spatiotemporal patterns of active epigenetic turnover. PRX Life. 4, 013018.","ieee":"F. Olmeda, M. Gupta, O. Bektas, and S. Rulands, “Spatiotemporal patterns of active epigenetic turnover,” <i>PRX Life</i>, vol. 4. American Physical Society, 2026."},"DOAJ_listed":"1","acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 950349 and the Marie Skłodowska-Curie Grant Agreement No. 101034413. The computations in this paper were run in part on the the FASRC Cannon cluster supported by the FAS Division of Science Research Computing Group at Harvard University and the cluster of the Max Planck Institute for the Physics of Complex Systems.","publication_identifier":{"eissn":["2835-8279"]},"OA_type":"gold","OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"PRX Life","status":"public","ec_funded":1,"article_number":"013018","title":"Spatiotemporal patterns of active epigenetic turnover","oa_version":"Published Version","date_published":"2026-02-09T00:00:00Z","PlanS_conform":"1","quality_controlled":"1","month":"02","year":"2026","publisher":"American Physical Society","volume":4,"fulldoi":"https://doi.org/10.1103/89bj-79g5","file":[{"date_created":"2026-02-24T06:53:05Z","file_id":"21351","creator":"dernst","content_type":"application/pdf","relation":"main_file","file_name":"2026_PRXLife_Olmeda.pdf","success":1,"access_level":"open_access","date_updated":"2026-02-24T06:53:05Z","checksum":"df9776422862d1d02c66d98e2d620849","file_size":5857833}],"file_date_updated":"2026-02-24T06:53:05Z","date_updated":"2026-02-24T06:54:32Z","_id":"21275","language":[{"iso":"eng"}],"ddc":["570"],"intvolume":"         4","has_accepted_license":"1","oa":1,"doi":"10.1103/89bj-79g5","article_processing_charge":"Yes","abstract":[{"text":"DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives rise to a biochemical cycle and active turnover of DNA methylation. While the ensuing biochemical oscillations have been implicated in the regulation of cell differentiation, their functional role and spatiotemporal dynamics are unknown. In this work, we demonstrate that chromatin-mediated coupling between these local biochemical cycles can lead to the emergence of phase-locked domains, regions of locally synchronized turnover activity, whose coarsening is arrested by genomic heterogeneity. We introduce a minimal model based on stochastic oscillators with constrained long-range and nonreciprocal interactions, shaped by the local chromatin organization. Through a combination of analytical theory and stochastic simulations, we predict both the degree of synchronization and the typical size of emergent phase-locked domains. We qualitatively test these predictions using single-cell sequencing data. Our results show that DNA methylation turnover exhibits surprisingly rich spatiotemporal patterns that may be used by cells to control cell differentiation.","lang":"eng"}],"department":[{"_id":"EdHa"}],"author":[{"full_name":"Olmeda, Fabrizio","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","first_name":"Fabrizio","last_name":"Olmeda"},{"full_name":"Gupta, Misha","first_name":"Misha","last_name":"Gupta"},{"first_name":"Onurcan","last_name":"Bektas","full_name":"Bektas, Onurcan"},{"last_name":"Rulands","first_name":"Steffen","full_name":"Rulands, Steffen"}]},{"date_updated":"2026-02-24T08:02:58Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s41748-026-01052-3"}],"fulldoi":"https://doi.org/10.1007/s41748-026-01052-3","year":"2026","month":"02","publisher":"Springer Nature","article_processing_charge":"Yes (via OA deal)","abstract":[{"text":"Tropospheric ozone has the potential to become an increasingly pressing public health issue in Bogotá, Colombia, due to rising concentrations across the city driven by complex interactions among emissions, meteorology, and urban structure. This study presents a comprehensive spatiotemporal analysis of ozone levels from 2013 to 2023 and assesses the associated health burden using mortality data from the same period. Results reveal a consistent upward trend in ozone concentrations, particularly in northern, western, and southern localities, with seasonal peaks linked to biomass burning and photochemical conditions. Mortality analysis, based on the Global Exposure Mortality Model, estimates that 18.3% of all deaths among individuals aged 25 and older are attributable to long-term ozone exposure. The highest burdens are found in densely populated and socioeconomically vulnerable areas such as Kennedy, Suba, and Ciudad Bolívar, with the elderly being the most affected. Building on these findings, we developed a machine learning prediction model for ozone using a convolutional merge with a long-short term memory network architecture trained on air quality and meteorological variables. The model demonstrated strong predictive performance (mean Rho=0.86, RMSE=3.5 μg/m3) across monitoring stations (17 with at least 35000 data points), supporting its potential application in real-time early warning systems across Bogotá. This integrated approach highlights the importance of localized air quality management, combining epidemiological assessment with predictive modeling. The findings underscore the urgency of implementing region-specific mitigation strategies and improving monitoring infrastructure to reduce health risks from ozone exposure in Bogotá’s rapidly growing urban environment.","lang":"eng"}],"department":[{"_id":"CaMu"}],"doi":"10.1007/s41748-026-01052-3","author":[{"last_name":"Bustos","first_name":"Daniela","full_name":"Bustos, Daniela"},{"last_name":"Garcia","first_name":"Diana","full_name":"Garcia, Diana"},{"full_name":"Rojas, Nestor Y.","last_name":"Rojas","first_name":"Nestor Y."},{"full_name":"Lopez-Barrera, Ellie A.","last_name":"Lopez-Barrera","first_name":"Ellie A."},{"last_name":"Peña-Rincon","first_name":"Carlos","full_name":"Peña-Rincon, Carlos"},{"last_name":"Casallas Garcia","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","orcid":"0000-0002-1988-5035","first_name":"Alejandro","full_name":"Casallas Garcia, Alejandro"}],"_id":"21344","ddc":["550"],"has_accepted_license":"1","oa":1,"language":[{"iso":"eng"}],"citation":{"ista":"Bustos D, Garcia D, Rojas NY, Lopez-Barrera EA, Peña-Rincon C, Casallas Garcia A. 2026. Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. Earth Systems and Environment.","ieee":"D. Bustos, D. Garcia, N. Y. Rojas, E. A. Lopez-Barrera, C. Peña-Rincon, and A. Casallas Garcia, “Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia,” <i>Earth Systems and Environment</i>. Springer Nature, 2026.","apa":"Bustos, D., Garcia, D., Rojas, N. Y., Lopez-Barrera, E. A., Peña-Rincon, C., &#38; Casallas Garcia, A. (2026). Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. <i>Earth Systems and Environment</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s41748-026-01052-3\">https://doi.org/10.1007/s41748-026-01052-3</a>","short":"D. Bustos, D. Garcia, N.Y. Rojas, E.A. Lopez-Barrera, C. Peña-Rincon, A. Casallas Garcia, Earth Systems and Environment (2026).","mla":"Bustos, Daniela, et al. “Ozone Trends and Mortality Risk: The Growing Need for Machine Learning Predictions in Bogotá, Colombia.” <i>Earth Systems and Environment</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s41748-026-01052-3\">10.1007/s41748-026-01052-3</a>.","chicago":"Bustos, Daniela, Diana Garcia, Nestor Y. Rojas, Ellie A. Lopez-Barrera, Carlos Peña-Rincon, and Alejandro Casallas Garcia. “Ozone Trends and Mortality Risk: The Growing Need for Machine Learning Predictions in Bogotá, Colombia.” <i>Earth Systems and Environment</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s41748-026-01052-3\">https://doi.org/10.1007/s41748-026-01052-3</a>.","ama":"Bustos D, Garcia D, Rojas NY, Lopez-Barrera EA, Peña-Rincon C, Casallas Garcia A. Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia. <i>Earth Systems and Environment</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s41748-026-01052-3\">10.1007/s41748-026-01052-3</a>"},"project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020"}],"acknowledgement":"EAL-B and CP-R received support from Sergio Arboleda University through project No. IN.BG.086.24.014. AC acknowledges support by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. We thank two anonymous reviewers for thein insightful comments that largely improve the manuscript. Open access funding provided by Institute of Science and Technology (IST Austria). This work was funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. The work also received funding from Sergio Arboleda University through project No. IN.BG.086.24.014.","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"day":"20","date_created":"2026-02-23T08:26:51Z","article_type":"original","corr_author":"1","date_published":"2026-02-20T00:00:00Z","ec_funded":1,"title":"Ozone trends and mortality risk: The growing need for machine learning predictions in Bogotá, Colombia","oa_version":"Published Version","quality_controlled":"1","PlanS_conform":"1","publication_identifier":{"issn":["2509-9426"],"eissn":["2509-9434"]},"publication_status":"epub_ahead","publication":"Earth Systems and Environment","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","OA_place":"publisher","OA_type":"hybrid"},{"quality_controlled":"1","date_published":"2026-03-01T00:00:00Z","ec_funded":1,"oa_version":"Published Version","article_number":"e2025MS005343","title":"Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Journal of Advances in Modeling Earth Systems","status":"public","OA_type":"gold","OA_place":"publisher","publication_identifier":{"eissn":["1942-2466"]},"acknowledgement":"We thank Peter Bechtold, Lukas Brunner, Peter Dueben, Richard Forbes, Estibaliz Gascon, and Benoit Vanniere for providing insightful comments on the present study. We also thank Sebastian Milinski, Xabier Pedruzo and Thomas Rackow for their contributions to setting up IFS-FESOM for nextGEMS. We are also grateful to Dr. Walter Hannah and an anonymous reviewer for their constructive comments, which improved the original version of the manuscript. D. Takasuka was supported by JSPS KAKENHI Grants 20H05728 and 24K22893 and by JSPS Core-to-Core Program, “International Core-to-Core Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001). T. Becker was supported by the Horizon 2020 project nextGEMS under grant agreement number 101003470. J. Bao acknowledges funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant agreement No 101034413). The ICON and IFS simulations were performed with supercomputing resources of the German Climate Computing Centre (Deutsches Klimarechenzentrum, DKRZ) granted by its Scientific Steering Committee (WLA) under project ID 1235. The NICAM simulation was performed on the supercomputer Fugaku (proposal numbers hp220132, hp230078, hp230108, hp230278, and hp240267).","DOAJ_listed":"1","citation":{"apa":"Takasuka, D., Becker, T., &#38; Bao, J. (2026). Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>","short":"D. Takasuka, T. Becker, J. Bao, Journal of Advances in Modeling Earth Systems 18 (2026).","ista":"Takasuka D, Becker T, Bao J. 2026. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. Journal of Advances in Modeling Earth Systems. 18(3), e2025MS005343.","ieee":"D. Takasuka, T. Becker, and J. Bao, “Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3. Wiley, 2026.","ama":"Takasuka D, Becker T, Bao J. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. 2026;18(3). doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>","mla":"Takasuka, Daisuke, et al. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3, e2025MS005343, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>.","chicago":"Takasuka, Daisuke, Tobias Becker, and Jiawei Bao. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>."},"project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020"}],"scopus_import":"1","day":"01","date_created":"2026-04-05T22:01:31Z","article_type":"original","corr_author":"1","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"author":[{"first_name":"Daisuke","last_name":"Takasuka","full_name":"Takasuka, Daisuke"},{"full_name":"Becker, Tobias","first_name":"Tobias","last_name":"Becker"},{"last_name":"Bao","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","first_name":"Jiawei","full_name":"Bao, Jiawei"}],"article_processing_charge":"Yes","department":[{"_id":"CaMu"}],"abstract":[{"text":"We compare three global kilometer-scale models (ICON, IFS and NICAM) to clarify the advantages and challenges of high-resolution global weather and climate modeling, using different approaches to represent convection, from fully parameterized to fully explicit. Our analysis focuses on tropical precipitation characteristics spanning a wide range of spatio-temporal scales—including the diurnal cycle, extreme precipitation, convective organization, and the Madden-Julian Oscillation (MJO)—along with interactions between convection and the thermodynamic environment. All three models commonly show weaker convective organization with smaller precipitation cells than observed, though the strength of the bias varies by model. This diversity is introduced by differences in the representation of (a) convective initiation affected by the convective sensitivity to moisture and (b) tropospheric moistening associated with deep convection. Models with stronger thermodynamic-convection coupling increase environmental moisture near convection, thereby enhancing convective organization. This has important upscale effects on the MJO; while IFS and NICAM capture its eastward propagation well, ICON has difficulty reproducing it. The amplitudes and phases of precipitation diurnal cycles over land show much greater disagreement among the models than over ocean, influenced by how convection is initiated. Biases in rain evaporation and cold pool formation hinder the propagation of mesoscale convection, leading to errors such as the misrepresentation of nocturnal convection moving off the coast of Sumatra in IFS and ICON. These results highlight the importance of thermodynamic-convection coupling in realistically simulating tropical convection across scales. To improve this coupling, kilometer-scale models require better representation of the interaction between resolved convection and three-dimensional turbulent mixing.","lang":"eng"}],"doi":"10.1029/2025MS005343","ddc":["550"],"intvolume":"        18","oa":1,"has_accepted_license":"1","language":[{"iso":"eng"}],"_id":"21657","issue":"3","date_updated":"2026-06-16T10:43:35Z","file_date_updated":"2026-04-07T09:11:23Z","file":[{"date_updated":"2026-04-07T09:11:23Z","access_level":"open_access","file_size":3854313,"checksum":"ca7dac4bab31348d0640ed22580c6dce","date_created":"2026-04-07T09:11:23Z","file_name":"2026_JAMES_Takasuka.pdf","relation":"main_file","success":1,"creator":"dernst","file_id":"21665","content_type":"application/pdf"}],"fulldoi":"https://doi.org/10.1029/2025MS005343","year":"2026","month":"03","publisher":"Wiley","volume":18},{"citation":{"chicago":"Hartmanns, Arnd, Sebastian Junges, Tim Quatmann, and Maximilian Weininger. “The Revised Practitioner’s Guide to MDP Model Checking Algorithms.” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s10009-026-00848-y\">https://doi.org/10.1007/s10009-026-00848-y</a>.","mla":"Hartmanns, Arnd, et al. “The Revised Practitioner’s Guide to MDP Model Checking Algorithms.” <i>International Journal on Software Tools for Technology Transfer</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s10009-026-00848-y\">10.1007/s10009-026-00848-y</a>.","ama":"Hartmanns A, Junges S, Quatmann T, Weininger M. The revised practitioner’s guide to MDP model checking algorithms. <i>International Journal on Software Tools for Technology Transfer</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s10009-026-00848-y\">10.1007/s10009-026-00848-y</a>","ieee":"A. Hartmanns, S. Junges, T. Quatmann, and M. Weininger, “The revised practitioner’s guide to MDP model checking algorithms,” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2026.","ista":"Hartmanns A, Junges S, Quatmann T, Weininger M. 2026. The revised practitioner’s guide to MDP model checking algorithms. International Journal on Software Tools for Technology Transfer.","short":"A. Hartmanns, S. Junges, T. Quatmann, M. Weininger, International Journal on Software Tools for Technology Transfer (2026).","apa":"Hartmanns, A., Junges, S., Quatmann, T., &#38; Weininger, M. (2026). The revised practitioner’s guide to MDP model checking algorithms. <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10009-026-00848-y\">https://doi.org/10.1007/s10009-026-00848-y</a>"},"project":[{"call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"related_material":{"record":[{"id":"21668","relation":"software","status":"public"}]},"acknowledgement":"This research was funded by the European Union’s Horizon 2020 research and innovation programme under Marie Skłodowska-Curie grant agreements 101008233 (MISSION)\r\nand 101034413 (IST-BRIDGE), by the Interreg North Sea project STORM_SAFE, by a KI-Starter grant from the Ministerium für Kultur und Wissenschaft NRW, by NWO VENI grant no. 639.021.754, and by NWO VIDI grant VI.Vidi.223.110 (TruSTy). Experiments were performed with computing resources granted by RWTH Aachen University under project rwth1632.","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","article_type":"original","scopus_import":"1","day":"09","date_created":"2026-04-05T22:01:32Z","date_published":"2026-03-09T00:00:00Z","title":"The revised practitioner’s guide to MDP model checking algorithms","oa_version":"Published Version","ec_funded":1,"quality_controlled":"1","publication_identifier":{"eissn":["1433-2787"],"issn":["1433-2779"]},"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"International Journal on Software Tools for Technology Transfer","publication_status":"epub_ahead","OA_type":"hybrid","OA_place":"publisher","date_updated":"2026-04-07T09:52:54Z","main_file_link":[{"url":"https://doi.org/10.1007/s10009-026-00848-y","open_access":"1"}],"keyword":["Quantitative model checking","Markov decision process","Linear programming","Value iteration","Policy iteration"],"fulldoi":"https://doi.org/10.1007/s10009-026-00848-y","month":"03","year":"2026","publisher":"Springer Nature","abstract":[{"lang":"eng","text":"Model checking undiscounted reachability and expected-reward properties on Markov decision processes (MDPs) are key for the verification of systems that act under uncertainty. Popular algorithms are policy iteration and variants of value iteration; in tool competitions, most participants rely on the latter. These algorithms generally need worst-case exponential time. However, the problem can equally be formulated as a linear programme, solvable in polynomial time. In this paper, we give a detailed overview of today’s state-of-the-art algorithms for MDP model checking with a focus on performance and correctness. We highlight their fundamental differences, and describe various optimizations and implementation variants. We experimentally compare floating-point and exact-arithmetic implementations of all algorithms on three benchmark sets using two probabilistic model checkers. Our results show that (optimistic) value iteration is a sensible default, but other algorithms are preferable in specific settings. This paper thereby provides a guide for MDP verification practitioners—tool builders and users alike."}],"department":[{"_id":"KrCh"}],"article_processing_charge":"Yes (in subscription journal)","doi":"10.1007/s10009-026-00848-y","author":[{"full_name":"Hartmanns, Arnd","first_name":"Arnd","last_name":"Hartmanns"},{"first_name":"Sebastian","last_name":"Junges","full_name":"Junges, Sebastian"},{"first_name":"Tim","last_name":"Quatmann","full_name":"Quatmann, Tim"},{"first_name":"Maximilian","id":"02ab0197-cc70-11ed-ab61-918e71f56881","orcid":"0000-0002-0163-2152","last_name":"Weininger","full_name":"Weininger, Maximilian"}],"_id":"21661","oa":1,"has_accepted_license":"1","ddc":["000"],"language":[{"iso":"eng"}]},{"date_updated":"2026-04-28T13:35:53Z","file_date_updated":"2026-04-21T06:07:22Z","file":[{"checksum":"2cd4ae120b14b244f5b2f50eaae0efc1","file_size":1544417,"date_updated":"2026-04-21T06:07:22Z","access_level":"open_access","success":1,"relation":"main_file","file_name":"Gio_Casallas_2026.pdf","content_type":"application/pdf","creator":"acasalla","file_id":"21756","date_created":"2026-04-21T06:07:22Z"}],"fulldoi":"https://doi.org/10.1029/2025gl119921","month":"04","year":"2026","publisher":"Wiley","volume":53,"author":[{"full_name":"Biagioli, Giovanni","first_name":"Giovanni","last_name":"Biagioli"},{"first_name":"Giulio","last_name":"Mandorli","full_name":"Mandorli, Giulio"},{"last_name":"Freischem","first_name":"Lilli Johanna","full_name":"Freischem, Lilli Johanna"},{"full_name":"Casallas Garcia, Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","first_name":"Alejandro","orcid":"0000-0002-1988-5035","last_name":"Casallas Garcia"},{"full_name":"Tompkins, Adrian Mark","first_name":"Adrian Mark","last_name":"Tompkins"}],"article_processing_charge":"Yes","abstract":[{"lang":"eng","text":"Tropical shallow clouds are a major source of uncertainty in Earth's climate sensitivity, especially through their spatial arrangement, which global climate models do not represent. Efforts to understand their organization have partly relied on classifying observed scenes, identifying four patterns as archetypal regimes. Here we analyze geostationary satellite imagery of the western tropical Atlantic using the L‐function, a tool based on point pattern theory that quantifies cloud organization across spatial scales. Classical examples of the four patterns show distinct L‐function fingerprints, revealing their characteristic clustering and regularity scales and aiding physical interpretation. Yet, when evaluating many scenes at fixed spatial scales, the L‐function distribution lacks the distinct modes expected from discrete regimes. This is corroborated by analyses of other organization indices employing diverse approaches, from inter‐cloud nearest‐neighbor distances to fractal analysis. Implications for the parameterization of mesoscale cloud organization in climate models are discussed."}],"department":[{"_id":"CaMu"}],"doi":"10.1029/2025gl119921","ddc":["550"],"intvolume":"        53","has_accepted_license":"1","oa":1,"language":[{"iso":"eng"}],"_id":"21755","issue":"8","DOAJ_listed":"1","acknowledgement":"GB was supported by an ICTP Postdoctoral Research Fellowship Agreement. GM was supported by the CNRS. AC was supported by the European Union's Horizon 2020 research and innovation programme Marie Sklodowska-Curie Grant agreement No 101034413. LJF acknowledges funding from the NERC Doctoral Training Partnership in Environmental Research Grant NE/S007474/1. We thank three anonymous reviewers and Jiawei Bao for their insightful comments, which greatly improved this manuscript.","citation":{"mla":"Biagioli, Giovanni, et al. “Spatial Patterns of Shallow Clouds: Challenging the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>, vol. 53, no. 8, e2025GL119921, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2025gl119921\">10.1029/2025gl119921</a>.","chicago":"Biagioli, Giovanni, Giulio Mandorli, Lilli Johanna Freischem, Alejandro Casallas Garcia, and Adrian Mark Tompkins. “Spatial Patterns of Shallow Clouds: Challenging the Concept of Defined Regimes.” <i>Geophysical Research Letters</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2025gl119921\">https://doi.org/10.1029/2025gl119921</a>.","ama":"Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. Spatial patterns of shallow clouds: Challenging the concept of defined regimes. <i>Geophysical Research Letters</i>. 2026;53(8). doi:<a href=\"https://doi.org/10.1029/2025gl119921\">10.1029/2025gl119921</a>","ista":"Biagioli G, Mandorli G, Freischem LJ, Casallas Garcia A, Tompkins AM. 2026. Spatial patterns of shallow clouds: Challenging the concept of defined regimes. Geophysical Research Letters. 53(8), e2025GL119921.","ieee":"G. Biagioli, G. Mandorli, L. J. Freischem, A. Casallas Garcia, and A. M. Tompkins, “Spatial patterns of shallow clouds: Challenging the concept of defined regimes,” <i>Geophysical Research Letters</i>, vol. 53, no. 8. Wiley, 2026.","apa":"Biagioli, G., Mandorli, G., Freischem, L. J., Casallas Garcia, A., &#38; Tompkins, A. M. (2026). Spatial patterns of shallow clouds: Challenging the concept of defined regimes. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2025gl119921\">https://doi.org/10.1029/2025gl119921</a>","short":"G. Biagioli, G. Mandorli, L.J. Freischem, A. Casallas Garcia, A.M. Tompkins, Geophysical Research Letters 53 (2026)."},"project":[{"call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"scopus_import":"1","day":"28","date_created":"2026-04-21T06:04:41Z","article_type":"original","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"quality_controlled":"1","PlanS_conform":"1","date_published":"2026-04-28T00:00:00Z","ec_funded":1,"article_number":"e2025GL119921","oa_version":"Published Version","title":"Spatial patterns of shallow clouds: Challenging the concept of defined regimes","publication":"Geophysical Research Letters","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","status":"public","OA_type":"gold","OA_place":"publisher","publication_identifier":{"issn":["0094-8276"],"eissn":["1944-8007"]}},{"date_updated":"2026-04-28T13:08:39Z","file_date_updated":"2026-04-28T13:06:00Z","file":[{"date_created":"2026-04-28T13:06:00Z","success":1,"relation":"main_file","file_name":"2026_AstrophysicalJournal_PerezCouto.pdf","content_type":"application/pdf","file_id":"21773","creator":"dernst","date_updated":"2026-04-28T13:06:00Z","access_level":"open_access","checksum":"c3daf49261a9933c079854c38eec316f","file_size":2905627}],"fulldoi":"https://doi.org/10.3847/1538-4357/ae56ff","volume":1001,"year":"2026","month":"04","publisher":"IOP Publishing","author":[{"first_name":"X.","last_name":"Pérez-Couto","full_name":"Pérez-Couto, X."},{"id":"a8df4360-4328-11ee-8f1a-e502d0c83fc2","orcid":"0000-0002-3150-8988","first_name":"Santiago","last_name":"Torres Rodriguez","full_name":"Torres Rodriguez, Santiago"},{"full_name":"Villaver, E.","first_name":"E.","last_name":"Villaver"},{"full_name":"Mustill, A. J.","last_name":"Mustill","first_name":"A. J."},{"full_name":"Manteiga, M.","first_name":"M.","last_name":"Manteiga"}],"abstract":[{"text":"3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua and 2I/Borisov. Its unusually high excess velocity and active cometary nature make it a key probe of the Galactic population of icy planetesimals. Understanding its origin requires its past trajectory through the Galaxy to be traced and the possible role of stellar encounters to be assessed, both as a potential origin and a perturber to its orbit. We integrated the orbit of 3I/ATLAS backward in time for 10 Myr, together with a sample of Gaia DR3 stars with high-quality astrometry and radial velocities, to identify close passages within 2 pc. We identify 93 nominal encounters, 62 of which are significant at the 2σ level. However, none of these encounters produced any meaningful perturbation. The strongest perturber Gaia DR3 6863591389529611264 at 0.30 pc and with a relative velocity of 35 km s−1, imparted only a velocity change of ∣Δv∣  ≃  5  ×  10−4 km s−1 to the orbit of 3I/ATLAS. Our results indicate that no stellar flybys within the past 10 Myr and 500 pc contained in Gaia DR3 can account for the present trajectory of 3I/ATLAS or be associated with its origin. We further show that 3I/ATLAS is kinematically consistent with a thin-disk population, despite its large peculiar velocity.","lang":"eng"}],"department":[{"_id":"LiBu"}],"article_processing_charge":"Yes","doi":"10.3847/1538-4357/ae56ff","oa":1,"has_accepted_license":"1","intvolume":"      1001","ddc":["520"],"external_id":{"arxiv":["2509.07678"]},"language":[{"iso":"eng"}],"issue":"2","_id":"21760","acknowledgement":"We thank the anonymous referee for a careful reading of the manuscript and for constructive comments that improved the paper. X.P.C. and S.T. thank J.L. Gragera-Más and Ylva Götberg for their valuable feedback and comments. X.P.C. acknowledges financial support from the Spanish National Programme for the Promotion of Talent and its Employability grant PRE2022-104959 cofunded by the European Social Fund. S.T. acknowledges the funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. E.V. acknowledges support from the DISCOBOLO project funded by the Spanish Ministerio de Ciencia, Innovación y Universidades under grant PID2021-127289NB-I00. A.J.M. acknowledges support from the Swedish National Space Agency (Career grant 2023-00146). X.P.C. and M.M. acknowledge support from the Spanish Ministerio de Ciencia, Innovaciòn y Universidades under grants PID2021122842OB-C22 and PID2024-157964OB-C22; from the Xunta de Galicia and the European Union (FEDER Galicia 2021-2027 Program) Ref. ED431B 2024/21, ED431B 2024/02, and CITIC ED431G 2023/01. This work has made use of data from the European Space Agency (ESA) Gaia mission and processed by the Gaia Data Processing and Analysis Consortium (DPAC). Funding for the DPAC has been provided by national institutions, particularly the institutions participating in the Gaia Multilateral Agreement.","DOAJ_listed":"1","citation":{"short":"X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A.J. Mustill, M. Manteiga, The Astrophysical Journal 1001 (2026).","apa":"Pérez-Couto, X., Torres Rodriguez, S., Villaver, E., Mustill, A. J., &#38; Manteiga, M. (2026). 3I/ATLAS: In search of the witnesses to its voyage. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae56ff\">https://doi.org/10.3847/1538-4357/ae56ff</a>","ieee":"X. Pérez-Couto, S. Torres Rodriguez, E. Villaver, A. J. Mustill, and M. Manteiga, “3I/ATLAS: In search of the witnesses to its voyage,” <i>The Astrophysical Journal</i>, vol. 1001, no. 2. IOP Publishing, 2026.","ista":"Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 2026. 3I/ATLAS: In search of the witnesses to its voyage. The Astrophysical Journal. 1001(2), 146.","ama":"Pérez-Couto X, Torres Rodriguez S, Villaver E, Mustill AJ, Manteiga M. 3I/ATLAS: In search of the witnesses to its voyage. <i>The Astrophysical Journal</i>. 2026;1001(2). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae56ff\">10.3847/1538-4357/ae56ff</a>","chicago":"Pérez-Couto, X., Santiago Torres Rodriguez, E. Villaver, A. J. Mustill, and M. Manteiga. “3I/ATLAS: In Search of the Witnesses to Its Voyage.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae56ff\">https://doi.org/10.3847/1538-4357/ae56ff</a>.","mla":"Pérez-Couto, X., et al. “3I/ATLAS: In Search of the Witnesses to Its Voyage.” <i>The Astrophysical Journal</i>, vol. 1001, no. 2, 146, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae56ff\">10.3847/1538-4357/ae56ff</a>."},"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"article_type":"original","arxiv":1,"scopus_import":"1","date_created":"2026-04-26T22:01:46Z","day":"20","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","quality_controlled":"1","PlanS_conform":"1","date_published":"2026-04-20T00:00:00Z","article_number":"146","title":"3I/ATLAS: In search of the witnesses to its voyage","oa_version":"Published Version","ec_funded":1,"status":"public","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"The Astrophysical Journal","OA_place":"publisher","OA_type":"gold","publication_identifier":{"eissn":["1538-4357"],"issn":["0004-637X"]}},{"citation":{"short":"P. Morawski, K.H. Petrova, Electronic Journal of Combinatorics 33 (2026).","apa":"Morawski, P., &#38; Petrova, K. H. (2026). Randomly perturbed digraphs also have bounded-degree spanning trees. <i>Electronic Journal of Combinatorics</i>. Electronic Journal of Combinatorics. <a href=\"https://doi.org/10.37236/13316\">https://doi.org/10.37236/13316</a>","ieee":"P. Morawski and K. H. Petrova, “Randomly perturbed digraphs also have bounded-degree spanning trees,” <i>Electronic Journal of Combinatorics</i>, vol. 33, no. 2. Electronic Journal of Combinatorics, 2026.","ista":"Morawski P, Petrova KH. 2026. Randomly perturbed digraphs also have bounded-degree spanning trees. Electronic Journal of Combinatorics. 33(2), P2.24.","ama":"Morawski P, Petrova KH. Randomly perturbed digraphs also have bounded-degree spanning trees. <i>Electronic Journal of Combinatorics</i>. 2026;33(2). doi:<a href=\"https://doi.org/10.37236/13316\">10.37236/13316</a>","chicago":"Morawski, Patryk, and Kalina H Petrova. “Randomly Perturbed Digraphs Also Have Bounded-Degree Spanning Trees.” <i>Electronic Journal of Combinatorics</i>. Electronic Journal of Combinatorics, 2026. <a href=\"https://doi.org/10.37236/13316\">https://doi.org/10.37236/13316</a>.","mla":"Morawski, Patryk, and Kalina H. Petrova. “Randomly Perturbed Digraphs Also Have Bounded-Degree Spanning Trees.” <i>Electronic Journal of Combinatorics</i>, vol. 33, no. 2, P2.24, Electronic Journal of Combinatorics, 2026, doi:<a href=\"https://doi.org/10.37236/13316\">10.37236/13316</a>."},"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"acknowledgement":"We thank the anonymous referees for many helpful comments on an earlier version of this\r\narticle. Kalina Petrova was supported by grant no. CRSII5 173721 of the Swiss National\r\nScience Foundation, and by the European Union’s Horizon 2020 research and innovation\r\nprogramme under the Marie Sk lodowska-Curie grant agreement No. 101034413","DOAJ_listed":"1","license":"https://creativecommons.org/licenses/by-nd/4.0/","type":"journal_article","tmp":{"short":"CC BY-ND (4.0)","image":"/image/cc_by_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nd/4.0/legalcode","name":"Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)"},"day":"08","date_created":"2026-05-17T22:02:11Z","scopus_import":"1","article_type":"original","arxiv":1,"corr_author":"1","date_published":"2026-05-08T00:00:00Z","ec_funded":1,"article_number":"P2.24","oa_version":"Published Version","title":"Randomly perturbed digraphs also have bounded-degree spanning trees","quality_controlled":"1","publication_identifier":{"eissn":["1077-8926"]},"publication":"Electronic Journal of Combinatorics","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","status":"public","OA_type":"gold","OA_place":"publisher","file_date_updated":"2026-05-18T08:46:26Z","file":[{"date_created":"2026-05-18T08:46:26Z","relation":"main_file","file_name":"2026_ElectrJournCombinatorics_Morawski.pdf","success":1,"file_id":"21893","creator":"dernst","content_type":"application/pdf","access_level":"open_access","date_updated":"2026-05-18T08:46:26Z","checksum":"9e8402cb2e8870ba7ded9ae7b308201a","file_size":399969}],"date_updated":"2026-05-18T08:50:18Z","fulldoi":"https://doi.org/10.37236/13316","month":"05","year":"2026","publisher":"Electronic Journal of Combinatorics","volume":33,"article_processing_charge":"Yes","department":[{"_id":"MaKw"}],"abstract":[{"text":"We show that a randomly perturbed digraph, where we start with a dense digraph Dα and add a small number of random edges to it, will typically contain a fixed orientation of a bounded-degree spanning tree. This answers a question posed by Araujo, Balogh, Krueger, Piga and Treglown and generalizes the corresponding result for randomly perturbed graphs by Krivelevich, Kwan and Sudakov. More specifically, we prove that there exists a constant c=c(α,Δ) such that if \r\nT is an oriented tree with maximum degree Δ and Dα is an n-vertex digraph with minimum semidegree αn, then the graph obtained by adding cn uniformly random edges to Dα will contain T with high probability.","lang":"eng"}],"doi":"10.37236/13316","author":[{"last_name":"Morawski","first_name":"Patryk","full_name":"Morawski, Patryk"},{"full_name":"Petrova, Kalina H","last_name":"Petrova","first_name":"Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381"}],"_id":"21884","issue":"2","ddc":["510"],"has_accepted_license":"1","intvolume":"        33","oa":1,"language":[{"iso":"eng"}],"external_id":{"arxiv":["2306.14648"]}},{"author":[{"full_name":"Christoph, Micha","first_name":"Micha","last_name":"Christoph"},{"last_name":"Nenadov","first_name":"Rajko","full_name":"Nenadov, Rajko"},{"last_name":"Petrova","first_name":"Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","full_name":"Petrova, Kalina H"}],"page":"254-267","article_processing_charge":"Yes (via OA deal)","abstract":[{"text":"We show that if n is odd and p>=Clog n/n, then with high probability Hamilton cycles in G(n,p) span its cycle space. More generally, we show this holds for a class of graphs satisfying certain natural pseudorandom properties. The proof is based on a novel idea of parity-switchers, which can be thought of as analogues of absorbers in the context of cycle spaces. As another application of our method, we show that Hamilton cycles in a near-Dirac graph G, that is, a graph G with odd n vertices and minimum degree n/2+C for sufficiently large constant C, span its cycle space.\r\n","lang":"eng"}],"department":[{"_id":"MaKw"}],"doi":"10.1016/j.jctb.2025.09.002","ddc":["510"],"oa":1,"has_accepted_license":"1","intvolume":"       176","language":[{"iso":"eng"}],"external_id":{"arxiv":["2402.01447"],"isi":["001585783400001"]},"_id":"20422","date_updated":"2026-01-05T13:29:52Z","file_date_updated":"2026-01-05T13:29:34Z","file":[{"checksum":"60676af4af4b3243ba187e7d65440d99","file_size":688924,"access_level":"open_access","date_updated":"2026-01-05T13:29:34Z","creator":"dernst","file_id":"20953","content_type":"application/pdf","file_name":"2026_JourCombTheoryB_Christoph.pdf","relation":"main_file","success":1,"date_created":"2026-01-05T13:29:34Z"}],"fulldoi":"https://doi.org/10.1016/j.jctb.2025.09.002","year":"2026","month":"01","publisher":"Elsevier","volume":176,"quality_controlled":"1","PlanS_conform":"1","date_published":"2026-01-01T00:00:00Z","ec_funded":1,"oa_version":"Published Version","title":"The Hamilton space of pseudorandom graphs","publication":"Journal of Combinatorial Theory Series B","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","OA_type":"hybrid","OA_place":"publisher","publication_identifier":{"eissn":["1096-0902"],"issn":["0095-8956"]},"acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Image 1 Part of this research was conducted while the author was at Department of Computer Science, ETH Zürich, Switzerland. This author was supported by grant no. CRSII5 173721 of the Swiss National Science Foundation.","citation":{"ama":"Christoph M, Nenadov R, Petrova KH. The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. 2026;176:254-267. doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>","chicago":"Christoph, Micha, Rajko Nenadov, and Kalina H Petrova. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>.","mla":"Christoph, Micha, et al. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>, vol. 176, Elsevier, 2026, pp. 254–67, doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>.","short":"M. Christoph, R. Nenadov, K.H. Petrova, Journal of Combinatorial Theory Series B 176 (2026) 254–267.","apa":"Christoph, M., Nenadov, R., &#38; Petrova, K. H. (2026). The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>","ieee":"M. Christoph, R. Nenadov, and K. H. Petrova, “The Hamilton space of pseudorandom graphs,” <i>Journal of Combinatorial Theory Series B</i>, vol. 176. Elsevier, pp. 254–267, 2026.","ista":"Christoph M, Nenadov R, Petrova KH. 2026. The Hamilton space of pseudorandom graphs. Journal of Combinatorial Theory Series B. 176, 254–267."},"project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020"}],"day":"01","scopus_import":"1","date_created":"2025-10-05T22:01:34Z","arxiv":1,"article_type":"original","isi":1,"corr_author":"1","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"}},{"department":[{"_id":"MaKw"}],"abstract":[{"text":"In his study of graph codes, Alon introduced the concept of the odd-Ramsey number of a family of graphs H in Kn, defined as the minimum number of colours needed to colour the edges of K so that every copy of a graph H E H intersects some colour class in an odd number of edges. In this paper, we focus on complete bipartite graphs. First, we completely resolve the problem when H is the family of all spanning complete bipartite graphs on n vertices. We then focus on its subfamilies, that is, {Kt,n-t : t E T} for a fixed set of integers T c [[n/2]]. We prove that the odd-Ramsey problem is equivalent to determining the maximum dimension of a linear binary code avoiding codewords of given weights, and leverage known results from coding theory to deduce asymptotically tight bounds in our setting. We conclude with bounds for the odd-Ramsey numbers of fixed (that is, non-spanning) complete bipartite subgraphs.","lang":"eng"}],"article_processing_charge":"Yes (via OA deal)","doi":"10.1016/j.ejc.2025.104235","author":[{"last_name":"Boyadzhiyska","first_name":"Simona","full_name":"Boyadzhiyska, Simona"},{"full_name":"Das, Shagnik","last_name":"Das","first_name":"Shagnik"},{"first_name":"Thomas","last_name":"Lesgourgues","full_name":"Lesgourgues, Thomas"},{"full_name":"Petrova, Kalina H","last_name":"Petrova","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","first_name":"Kalina H"}],"_id":"20482","has_accepted_license":"1","intvolume":"       131","oa":1,"ddc":["500"],"external_id":{"isi":["001573380700001"],"arxiv":["2410.05887"]},"language":[{"iso":"eng"}],"file_date_updated":"2026-01-05T13:34:40Z","file":[{"file_name":"2026_EuropJourCombinatorics_Boyadzhiyska.pdf","relation":"main_file","success":1,"file_id":"20954","creator":"dernst","content_type":"application/pdf","date_created":"2026-01-05T13:34:40Z","file_size":563029,"checksum":"52883daa217398396cbf9b8ad9ddae92","date_updated":"2026-01-05T13:34:40Z","access_level":"open_access"}],"date_updated":"2026-01-05T13:34:48Z","fulldoi":"https://doi.org/10.1016/j.ejc.2025.104235","volume":131,"month":"01","year":"2026","publisher":"Elsevier","date_published":"2026-01-01T00:00:00Z","oa_version":"Published Version","article_number":"104235","title":"Odd-Ramsey numbers of complete bipartite graphs","ec_funded":1,"quality_controlled":"1","PlanS_conform":"1","publication_identifier":{"issn":["0195-6698"]},"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"European Journal of Combinatorics","publication_status":"published","OA_place":"publisher","OA_type":"hybrid","citation":{"ama":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. 2026;131. doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>","mla":"Boyadzhiyska, Simona, et al. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>, vol. 131, 104235, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>.","chicago":"Boyadzhiyska, Simona, Shagnik Das, Thomas Lesgourgues, and Kalina H Petrova. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>.","apa":"Boyadzhiyska, S., Das, S., Lesgourgues, T., &#38; Petrova, K. H. (2026). Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>","short":"S. Boyadzhiyska, S. Das, T. Lesgourgues, K.H. Petrova, European Journal of Combinatorics 131 (2026).","ista":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. 2026. Odd-Ramsey numbers of complete bipartite graphs. European Journal of Combinatorics. 131, 104235.","ieee":"S. Boyadzhiyska, S. Das, T. Lesgourgues, and K. H. Petrova, “Odd-Ramsey numbers of complete bipartite graphs,” <i>European Journal of Combinatorics</i>, vol. 131. Elsevier, 2026."},"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413"}],"acknowledgement":"The authors would like to thank Gilles Zémor for a helpful clarification on [3], Deepak Bal and Patrick Bennett for bringing [25] to their attention, and both referees for several helpful comments.\r\nS.B.: Most of this research was conducted while the author was at the School of Mathematics, University of Birmingham, Birmingham, United Kingdom. The research leading to these results was supported by EPSRC, United Kingdom, grant no. EP/V048287/1 and by ERC Advanced Grants “GeoScape”, no. 882971 and “ERMiD”, no. 101054936. There are no additional data beyond that contained within the main manuscript.\r\nS.D.: Research supported by Taiwan NSTC grants 111-2115-M-002-009-MY2 and 113-2628-M-002-008-MY4.\r\nK.P.: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Parts of this research was conducted while K.P. was at the Department of Computer Science, ETH Zürich, Switzerland, supported by Swiss National Science Foundation, Switzerland , grant no. CRSII5 173721.","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","arxiv":1,"article_type":"original","scopus_import":"1","day":"01","date_created":"2025-10-16T13:14:34Z","corr_author":"1","isi":1},{"related_material":{"record":[{"status":"public","relation":"earlier_version","id":"15168"}]},"acknowledgement":"This research was supported by the Charles University project PRIMUS/21/SCI/014, by the Ministry of Education, Youth\r\nand Sports of the Czech Republic under the project MSCAfellow5_MUNI (CZ.02.01.01/00/22_010/0003229), and by the\r\nAustrian Science Fund (FWF project P31312-N35). This research was funded by UKRI EP/X024431/1 and by a Clarendon\r\nFund Scholarship. This project has received funding from the European Union’s Horizon 2020 research and innovation\r\nprogramme under the Marie Skłodowska-Curie Grant Agreement No 101034413.\r\n","project":[{"_id":"26611F5C-B435-11E9-9278-68D0E5697425","grant_number":"P31312","name":"Algorithms for Embeddings and Homotopy Theory","call_identifier":"FWF"},{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"citation":{"mla":"Filakovský, Marek, et al. “Hardness of Linearly Ordered 4-Colouring of 3-Colourable 3-Uniform Hypergraphs.” <i>ACM Transactions on Computation Theory</i>, vol. 18, no. 2, 10, Association for Computing Machinery, 2026, doi:<a href=\"https://doi.org/10.1145/3779121\">10.1145/3779121</a>.","chicago":"Filakovský, Marek, Tamio Vesa Nakajima, Jakub Opršal, Gianluca Tasinato, and Uli Wagner. “Hardness of Linearly Ordered 4-Colouring of 3-Colourable 3-Uniform Hypergraphs.” <i>ACM Transactions on Computation Theory</i>. Association for Computing Machinery, 2026. <a href=\"https://doi.org/10.1145/3779121\">https://doi.org/10.1145/3779121</a>.","ama":"Filakovský M, Nakajima TV, Opršal J, Tasinato G, Wagner U. Hardness of linearly ordered 4-colouring of 3-colourable 3-uniform hypergraphs. <i>ACM Transactions on Computation Theory</i>. 2026;18(2). doi:<a href=\"https://doi.org/10.1145/3779121\">10.1145/3779121</a>","ista":"Filakovský M, Nakajima TV, Opršal J, Tasinato G, Wagner U. 2026. Hardness of linearly ordered 4-colouring of 3-colourable 3-uniform hypergraphs. ACM Transactions on Computation Theory. 18(2), 10.","ieee":"M. Filakovský, T. V. Nakajima, J. Opršal, G. Tasinato, and U. Wagner, “Hardness of linearly ordered 4-colouring of 3-colourable 3-uniform hypergraphs,” <i>ACM Transactions on Computation Theory</i>, vol. 18, no. 2. Association for Computing Machinery, 2026.","apa":"Filakovský, M., Nakajima, T. V., Opršal, J., Tasinato, G., &#38; Wagner, U. (2026). Hardness of linearly ordered 4-colouring of 3-colourable 3-uniform hypergraphs. <i>ACM Transactions on Computation Theory</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3779121\">https://doi.org/10.1145/3779121</a>","short":"M. Filakovský, T.V. Nakajima, J. Opršal, G. Tasinato, U. Wagner, ACM Transactions on Computation Theory 18 (2026)."},"corr_author":"1","article_type":"original","arxiv":1,"scopus_import":"1","date_created":"2026-07-05T22:01:37Z","day":"04","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","PlanS_conform":"1","quality_controlled":"1","article_number":"10","title":"Hardness of linearly ordered 4-colouring of 3-colourable 3-uniform hypergraphs","oa_version":"Published Version","ec_funded":1,"date_published":"2026-05-04T00:00:00Z","OA_place":"publisher","OA_type":"gold","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"ACM Transactions on Computation Theory","publication_identifier":{"issn":["1942-3454"],"eissn":["1942-3462"]},"date_updated":"2026-07-06T09:06:29Z","file":[{"checksum":"0399ab94085878fc810084845eabd627","file_size":941518,"access_level":"open_access","date_updated":"2026-07-06T09:03:02Z","success":1,"relation":"main_file","file_name":"2026_TransactionsGraphics_Filakovsky.pdf","content_type":"application/pdf","creator":"dernst","file_id":"22252","date_created":"2026-07-06T09:03:02Z"}],"file_date_updated":"2026-07-06T09:03:02Z","volume":18,"year":"2026","month":"05","publisher":"Association for Computing Machinery","keyword":["Constraint satisfaction problem","hypergraph colouring","promise problem","topological methods"],"fulldoi":"https://doi.org/10.1145/3779121","supplementarymaterial":"no","author":[{"full_name":"Filakovský, Marek","last_name":"Filakovský","first_name":"Marek","id":"3E8AF77E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Nakajima","first_name":"Tamio Vesa","full_name":"Nakajima, Tamio Vesa"},{"last_name":"Opršal","first_name":"Jakub","orcid":"0000-0003-1245-3456","id":"ec596741-c539-11ec-b829-c79322a91242","full_name":"Opršal, Jakub"},{"full_name":"Tasinato, Gianluca","first_name":"Gianluca","id":"0433290C-AF8F-11E9-A4C7-F729E6697425","last_name":"Tasinato"},{"full_name":"Wagner, Uli","last_name":"Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","first_name":"Uli","orcid":"0000-0002-1494-0568"}],"doi":"10.1145/3779121","abstract":[{"text":"A linearly ordered (LO) k-colouring of a hypergraph is a colouring of its vertices with colours 1, …, k such that each edge contains a unique maximal colour. Deciding whether an input hypergraph admits LO k-colouring with a fixed number of colours is NP-complete (and in the special case of graphs, LO colouring coincides with the usual graph colouring).\r\nHere, we investigate the complexity of approximating the “linearly ordered chromatic number” of a hypergraph. We prove that the following promise problem is NP-complete: Given a 3-uniform hypergraph, distinguish between the case that it is LO 3-colourable, and the case that it is not even LO 4-colourable. We prove this result by a combination of algebraic, topological, and combinatorial methods, building on and extending a topological approach for studying approximate graph colouring introduced by Krokhin, Opršal, Wrochna, and Živný (2023).","lang":"eng"}],"department":[{"_id":"UlWa"}],"researchdata_availability":"no","article_processing_charge":"Yes","external_id":{"arxiv":["2312.12981"]},"language":[{"iso":"eng"}],"das_tickbox":"0","oa":1,"has_accepted_license":"1","intvolume":"        18","ddc":["500"],"_id":"22247","issue":"2"},{"ec_funded":1,"oa_version":"Published Version","title":"Average sizes of mixed character sums","date_published":"2026-01-01T00:00:00Z","PlanS_conform":"1","quality_controlled":"1","publication_identifier":{"eissn":["1473-7124"],"issn":["0308-2105"]},"OA_place":"publisher","OA_type":"hybrid","publication_status":"epub_ahead","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Proceedings of the Royal Society of Edinburgh: Section A Mathematics","status":"public","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"citation":{"ista":"Wang V, Xu M. 2026. Average sizes of mixed character sums. Proceedings of the Royal Society of Edinburgh: Section A Mathematics., 1–15.","ieee":"V. Wang and M. Xu, “Average sizes of mixed character sums,” <i>Proceedings of the Royal Society of Edinburgh: Section A Mathematics</i>. Cambridge University Press, pp. 1–15, 2026.","apa":"Wang, V., &#38; Xu, M. (2026). Average sizes of mixed character sums. <i>Proceedings of the Royal Society of Edinburgh: Section A Mathematics</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/prm.2026.10123\">https://doi.org/10.1017/prm.2026.10123</a>","short":"V. Wang, M. Xu, Proceedings of the Royal Society of Edinburgh: Section A Mathematics (2026) 1–15.","mla":"Wang, Victor, and Max Xu. “Average Sizes of Mixed Character Sums.” <i>Proceedings of the Royal Society of Edinburgh: Section A Mathematics</i>, Cambridge University Press, 2026, pp. 1–15, doi:<a href=\"https://doi.org/10.1017/prm.2026.10123\">10.1017/prm.2026.10123</a>.","chicago":"Wang, Victor, and Max Xu. “Average Sizes of Mixed Character Sums.” <i>Proceedings of the Royal Society of Edinburgh: Section A Mathematics</i>. Cambridge University Press, 2026. <a href=\"https://doi.org/10.1017/prm.2026.10123\">https://doi.org/10.1017/prm.2026.10123</a>.","ama":"Wang V, Xu M. Average sizes of mixed character sums. <i>Proceedings of the Royal Society of Edinburgh: Section A Mathematics</i>. 2026:1-15. doi:<a href=\"https://doi.org/10.1017/prm.2026.10123\">10.1017/prm.2026.10123</a>"},"acknowledgement":"We thank Ofir Gorodetsky, Andrew Granville, Adam Harper, Youness Lamzouri,\r\nKannan Soundararajan, Ping Xi, and Matt Young for their interest, helpful discussions, and comments. Special thanks are due to Jonathan Bober, Oleksiy Klurman,\r\nand Besfort Shala for sending us a letter about Question 1.3, and to Hung Bui\r\nfor informing us of [7]. V.W. thanks Stanford University for its hospitality and is supported by the European Union’s Horizon 2020 research and innovation program\r\nunder the Marie Skłodowska–Curie Grant Agreement No. 101034413. M.X. is supported by a Simons Junior Fellowship from the Simons Society of Fellows at the\r\nSimons Foundation.","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"corr_author":"1","date_created":"2026-03-02T10:09:23Z","article_type":"original","arxiv":1,"doi":"10.1017/prm.2026.10123","article_processing_charge":"Yes (via OA deal)","researchdata_availability":"no","department":[{"_id":"TiBr"}],"abstract":[{"lang":"eng","text":"We prove that the average size of a mixed character sum (math. formular) (for a suitable smooth function w) is on the order of √x for all irrational real θ satisfying a weak Diophantine condition, where χ is drawn from the family of Dirichlet characters modulo a large prime r and where x 6 r. In contrast, it was proved by Harper that the average size is o(√x) for rational θ. Certain quadratic Diophantine equations play a key role in the present paper. "}],"author":[{"full_name":"Wang, Victor","orcid":"0000-0002-0704-7026","id":"76096395-aea4-11ed-a680-ab8ebbd3f1b9","first_name":"Victor","last_name":"Wang"},{"full_name":"Xu, Max","first_name":"Max","last_name":"Xu"}],"page":"1-15","_id":"21385","das_tickbox":"0","language":[{"iso":"eng"}],"external_id":{"arxiv":["2411.14181"]},"ddc":["510"],"oa":1,"has_accepted_license":"1","date_updated":"2026-07-16T08:39:57Z","main_file_link":[{"url":"https://doi.org/10.1017/prm.2026.10123","open_access":"1"}],"year":"2026","publisher":"Cambridge University Press","month":"01","fulldoi":"https://doi.org/10.1017/prm.2026.10123","supplementarymaterial":"no"},{"_id":"17437","external_id":{"isi":["001287455300001"]},"language":[{"iso":"eng"}],"das_tickbox":"1","has_accepted_license":"1","intvolume":"        31","oa":1,"ddc":["510"],"doi":"10.1007/s00031-024-09873-0","dataavailabilitystatement":"Not applicable.","department":[{"_id":"TaHa"}],"abstract":[{"lang":"eng","text":"We prove that the zero-fiber of the moment map of a totally negative quiver has rational singularities. Our proof consists in generalizing dimension bounds on jet spaces of this fiber, which were introduced by Budur. We also transfer the rational singularities property to other moduli spaces of objects in 2-Calabi-Yau categories, based on recent work of Davison. This has interesting arithmetic applications on quiver moment maps and moduli spaces of objects in 2-Calabi-Yau categories. First, we generalize results of Wyss on the asymptotic behaviour of counts of jets of quiver moment maps over finite fields. Moreover, we interpret the limit of counts of jets on a given moduli space as its p-adic volume under a canonical measure analogous to the measure built by Carocci, Orecchia and Wyss on certain moduli spaces of coherent sheaves."}],"researchdata_availability":"not applicable","article_processing_charge":"Yes (via OA deal)","page":"1047-1083","author":[{"full_name":"Vernet, Tanguy","last_name":"Vernet","id":"19f1e3bf-c59a-11ee-a1af-ed269948817b","first_name":"Tanguy"}],"volume":31,"publisher":"Springer Nature","year":"2026","month":"03","supplementarymaterial":"no","fulldoi":"https://doi.org/10.1007/s00031-024-09873-0","file":[{"date_created":"2026-07-23T05:50:09Z","creator":"dernst","file_id":"22385","content_type":"application/pdf","file_name":"2026_TransformationGroups_Vernet.pdf","relation":"main_file","success":1,"access_level":"open_access","date_updated":"2026-07-23T05:50:09Z","checksum":"8985b4154b730284d3412ddc9e55d965","file_size":912029}],"file_date_updated":"2026-07-23T05:50:09Z","date_updated":"2026-07-23T05:51:07Z","publication_identifier":{"eissn":["1531-586X"],"issn":["1083-4362"]},"OA_type":"hybrid","OA_place":"publisher","status":"public","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Transformation Groups","title":"Rational singularities for moment maps of totally negative quivers","oa_version":"Published Version","ec_funded":1,"date_published":"2026-03-01T00:00:00Z","PlanS_conform":"1","quality_controlled":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article","corr_author":"1","isi":1,"article_type":"original","day":"01","scopus_import":"1","date_created":"2024-08-18T22:01:04Z","project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"citation":{"ama":"Vernet T. Rational singularities for moment maps of totally negative quivers. <i>Transformation Groups</i>. 2026;31:1047-1083. doi:<a href=\"https://doi.org/10.1007/s00031-024-09873-0\">10.1007/s00031-024-09873-0</a>","chicago":"Vernet, Tanguy. “Rational Singularities for Moment Maps of Totally Negative Quivers.” <i>Transformation Groups</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00031-024-09873-0\">https://doi.org/10.1007/s00031-024-09873-0</a>.","mla":"Vernet, Tanguy. “Rational Singularities for Moment Maps of Totally Negative Quivers.” <i>Transformation Groups</i>, vol. 31, Springer Nature, 2026, pp. 1047–83, doi:<a href=\"https://doi.org/10.1007/s00031-024-09873-0\">10.1007/s00031-024-09873-0</a>.","short":"T. Vernet, Transformation Groups 31 (2026) 1047–1083.","apa":"Vernet, T. (2026). Rational singularities for moment maps of totally negative quivers. <i>Transformation Groups</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00031-024-09873-0\">https://doi.org/10.1007/s00031-024-09873-0</a>","ieee":"T. Vernet, “Rational singularities for moment maps of totally negative quivers,” <i>Transformation Groups</i>, vol. 31. Springer Nature, pp. 1047–1083, 2026.","ista":"Vernet T. 2026. Rational singularities for moment maps of totally negative quivers. Transformation Groups. 31, 1047–1083."},"mathsc":["14B05","14D23","14G20","16G20"],"acknowledgement":"I would like to warmly thank Dimitri Wyss for his guidance and supervision and Nero Budur for helpful discussions and answering all my questions on his previous works. I would also like to thank Francesca Carocci, Ben Davison, Lucien Hennecart and Olivier Schiffmann for helpful remarks and discussions during the writing of this paper. Finally, I would like to thank the anonymous referees for their careful reading and suggesting improvements in the exposition.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria). This work was supported by the Swiss National Science Foundation [No. 196960]. This project has also received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413."},{"file":[{"date_created":"2026-07-23T12:10:28Z","content_type":"application/pdf","creator":"dernst","file_id":"22398","success":1,"file_name":"2026_QuartJourRoyalMeteorobiolSoc_Agasthya.pdf","relation":"main_file","access_level":"open_access","date_updated":"2026-07-23T12:10:28Z","checksum":"8dd4d4d3ad027a4d26cbe5b1d66371e9","file_size":2665988}],"file_date_updated":"2026-07-23T12:10:28Z","date_updated":"2026-07-23T12:11:25Z","year":"2026","publisher":"Wiley","month":"01","volume":152,"supplementarymaterial":"yes","fulldoi":"https://doi.org/10.1002/qj.70044","dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author, L. Agasthya, upon reasonable request.","doi":"10.1002/qj.70044","researchdata_availability":"no","article_processing_charge":"Yes (via OA deal)","department":[{"_id":"CaMu"}],"abstract":[{"lang":"eng","text":"Moist convection is a fundamental process occurring in the Earth's atmosphere. It plays a central role in the weather and climate of the Tropics, where, to first order, the heating of the atmosphere by convection is in balance with the cooling of the atmosphere by the emission of radiation to outer space. In this study, we use a cloud-resolving model in radiative–convective equilibrium with an imposed constant rate of radiative cooling and study the response of moist convection to varying this rate of radiative cooling. In particular, we study two types of simulation: varying air temperature (VAT) simulations, where the air temperature is allowed to adjust to the imposed radiative cooling, and constant air temperature (CAT) simulations, where the surface temperature is tuned to ensure that the atmospheric temperature profile in the domain is constant. We recover the previously known result that, in response to increasing radiative cooling, the area of convection expands rapidly, while the intensity of convection does not change. We find that this response is explained by the increased boundary-layer variability in simulations with greater radiative cooling, which compensates for the decreasing temperature by adding a larger initial velocity close to the cloud base. We also propose a fundamental scaling of the non-dimensional cumulus mass flux in moist convection, which is robust across models of different complexity. We aim to bridge the gap between highly idealised prototypes of moist convection, such as the “Rainy–Bénard convection” introduced by Vallis et al., and comprehensive cloud-resolving models."}],"author":[{"full_name":"Agasthya, Lokahith N","last_name":"Agasthya","first_name":"Lokahith N","id":"cd100965-0804-11ed-9c55-f4878ff4e877"},{"full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","orcid":"0000-0001-5836-5350","first_name":"Caroline J","last_name":"Muller"}],"issue":"775","_id":"20590","language":[{"iso":"eng"}],"das_tickbox":"1","external_id":{"isi":["001595821400001"]},"ddc":["550"],"intvolume":"       152","has_accepted_license":"1","oa":1,"project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413"},{"name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","grant_number":"805041","_id":"629205d8-2b32-11ec-9570-e1356ff73576","call_identifier":"H2020"}],"citation":{"ista":"Agasthya LN, Muller CJ. 2026. Moist convection and radiative cooling: Dynamical response and scaling. Quarterly Journal of the Royal Meteorological Society. 152(775), e70044.","ieee":"L. N. Agasthya and C. J. Muller, “Moist convection and radiative cooling: Dynamical response and scaling,” <i>Quarterly Journal of the Royal Meteorological Society</i>, vol. 152, no. 775. Wiley, 2026.","apa":"Agasthya, L. N., &#38; Muller, C. J. (2026). Moist convection and radiative cooling: Dynamical response and scaling. <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley. <a href=\"https://doi.org/10.1002/qj.70044\">https://doi.org/10.1002/qj.70044</a>","short":"L.N. Agasthya, C.J. Muller, Quarterly Journal of the Royal Meteorological Society 152 (2026).","mla":"Agasthya, Lokahith N., and Caroline J. Muller. “Moist Convection and Radiative Cooling: Dynamical Response and Scaling.” <i>Quarterly Journal of the Royal Meteorological Society</i>, vol. 152, no. 775, e70044, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/qj.70044\">10.1002/qj.70044</a>.","chicago":"Agasthya, Lokahith N, and Caroline J Muller. “Moist Convection and Radiative Cooling: Dynamical Response and Scaling.” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/qj.70044\">https://doi.org/10.1002/qj.70044</a>.","ama":"Agasthya LN, Muller CJ. Moist convection and radiative cooling: Dynamical response and scaling. <i>Quarterly Journal of the Royal Meteorological Society</i>. 2026;152(775). doi:<a href=\"https://doi.org/10.1002/qj.70044\">10.1002/qj.70044</a>"},"acknowledgement":"The authors gratefully acknowledge discussions with Professor Robert Plant (University of Reading, UK), Professor Steve Sherwood (University of New South Wales, Australia), Professor Steve Tobias, Professor Douglas Parker, and Gregory Dritschel (University of Leeds, UK). Discussions with colleagues at the Institute of Science and Technology Austria played a large role in shaping this study. The authors are particularly grateful for inputs and discussions from Dr. Jiawei Bao, Dr. Alejandro Casallas, and Alzbeta Pechacova.\r\nThis project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska–Curie grant agreement No. 101034413. C. Muller gratefully acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). This research was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp). Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","type":"journal_article","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"isi":1,"corr_author":"1","day":"01","scopus_import":"1","date_created":"2025-11-02T23:01:34Z","article_type":"original","ec_funded":1,"article_number":"e70044","title":"Moist convection and radiative cooling: Dynamical response and scaling","oa_version":"Published Version","date_published":"2026-01-01T00:00:00Z","PlanS_conform":"1","quality_controlled":"1","publication_identifier":{"issn":["0035-9009"],"eissn":["1477-870X"]},"acknowledged_ssus":[{"_id":"ScienComp"}],"OA_place":"publisher","OA_type":"hybrid","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Quarterly Journal of the Royal Meteorological Society","publication_status":"published","status":"public"},{"citation":{"mla":"Ruzicka, Filip, et al. “A Century of Theories of Balancing Selection.” <i>Biological Reviews</i>, vol. 101, no. 2, 804–825, Wiley, 2026, doi:<a href=\"https://doi.org/10.1111/brv.70103\">10.1111/brv.70103</a>.","chicago":"Ruzicka, Filip, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, et al. “A Century of Theories of Balancing Selection.” <i>Biological Reviews</i>. Wiley, 2026. <a href=\"https://doi.org/10.1111/brv.70103\">https://doi.org/10.1111/brv.70103</a>.","ama":"Ruzicka F, Zwoinska MK, Goedert D, et al. A century of theories of balancing selection. <i>Biological Reviews</i>. 2026;101(2). doi:<a href=\"https://doi.org/10.1111/brv.70103\">10.1111/brv.70103</a>","ista":"Ruzicka F, Zwoinska MK, Goedert D, Kokko H, Li Richter X, Moodie IR, Nilén S, Olito C, Svensson EI, Czuppon P, Connallon T. 2026. A century of theories of balancing selection. Biological Reviews. 101(2), 804–825.","ieee":"F. Ruzicka <i>et al.</i>, “A century of theories of balancing selection,” <i>Biological Reviews</i>, vol. 101, no. 2. Wiley, 2026.","apa":"Ruzicka, F., Zwoinska, M. K., Goedert, D., Kokko, H., Li Richter, X., Moodie, I. R., … Connallon, T. (2026). A century of theories of balancing selection. <i>Biological Reviews</i>. Wiley. <a href=\"https://doi.org/10.1111/brv.70103\">https://doi.org/10.1111/brv.70103</a>","short":"F. Ruzicka, M.K. Zwoinska, D. Goedert, H. Kokko, X. Li Richter, I.R. Moodie, S. Nilén, C. Olito, E.I. Svensson, P. Czuppon, T. Connallon, Biological Reviews 101 (2026)."},"project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020"}],"acknowledgement":"We thank Brian Charlesworth, Deborah Charlesworth, and Sally Otto for extensive comments and suggestions. We also thank Göran Arnqvist, Adam Eyre-Walker, Philip Hedrick, Jitka Polechová, and Henrique Teotónio for further helpful comments on the manuscript. This work was supported by a H2020 Marie Skłodowska-Curie COFUND Action fellowship (#101034413, to F. R.), the Birgitta Sintring Foundation (#S2024-0007, to M. K. Z.), the Research Council of Norway (302619, to D. G.), the Alexander von Humboldt Foundation (to H. K.), the Swiss National Science Foundation (#211549, to X. L. R.), the Swedish Research Council (#2022-03603, to CO; #2020-03123, to E. I. S.) and the European Research Council (ERC-2023-STG-#101117517, to C. O.). We are particularly grateful to the European Society for Evolutionary Biology for funding a Special Topics Network workshop (to T. C., H. K., E. I. S.), from which this review began. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","license":"https://creativecommons.org/licenses/by-nc/4.0/","tmp":{"short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"type":"journal_article","article_type":"original","date_created":"2025-11-19T09:43:50Z","scopus_import":"1","day":"01","corr_author":"1","isi":1,"date_published":"2026-04-01T00:00:00Z","article_number":"804-825","title":"A century of theories of balancing selection","oa_version":"Published Version","ec_funded":1,"quality_controlled":"1","publication_identifier":{"issn":["1464-7931"],"eissn":["1469-185X"]},"status":"public","publication_status":"published","publication":"Biological Reviews","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","OA_type":"hybrid","file_date_updated":"2026-07-27T08:07:35Z","file":[{"date_created":"2026-07-27T08:07:35Z","content_type":"application/pdf","creator":"dernst","file_id":"22409","success":1,"file_name":"2026_BiologicalReviews_Ruzicka.pdf","relation":"main_file","access_level":"open_access","date_updated":"2026-07-27T08:07:35Z","checksum":"167d95cf0570d6e3653ab349b2a4355c","file_size":1757556}],"date_updated":"2026-07-27T08:08:09Z","pmid":1,"keyword":["evolutionary theory","population genetics","balancing selection","heterozygote advantage","trade-offs","negative frequency-dependent selection","fitness variation","mathematical modelling"],"supplementarymaterial":"yes","fulldoi":"https://doi.org/10.1111/brv.70103","volume":101,"publisher":"Wiley","month":"04","year":"2026","abstract":[{"lang":"eng","text":"Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short. Explaining the extensive genetic variation of fitness‐related traits is thus a longstanding puzzle in evolutionary biology, with cascading implications for ecology, conservation, and human health. Balancing selection – an umbrella term for scenarios in which natural selection maintains genetic variation – is a century‐old explanation to resolve this puzzle that has gained recent momentum from genome‐scale methods for detecting it. Yet evaluating whether balancing selection can, in fact, resolve the puzzle is challenging, given the logistical constraints of distinguishing balancing selection from alternative hypotheses and the daunting collection of theoretical models that formally underpin this debate. Here, we track the development of balancing selection theory over the last century and provide an accessible review of this rich collection of models. We first outline the range of biological scenarios that can generate balancing selection. We then examine how fundamental features of genetic systems – non‐random mating between individuals, ploidy levels, genetic drift, linkage, and genetic architectures of traits – have been progressively incorporated into the theory. We end by linking these theoretical predictions to ongoing empirical efforts to understand the evolutionary processes that explain genetic variation."}],"department":[{"_id":"BeVi"}],"researchdata_availability":"no","article_processing_charge":"Yes (via OA deal)","doi":"10.1111/brv.70103","author":[{"first_name":"Filip","id":"347955dd-57b0-11ee-9095-c28bdd368f4b","last_name":"Ruzicka","full_name":"Ruzicka, Filip"},{"first_name":"Martyna K.","last_name":"Zwoinska","full_name":"Zwoinska, Martyna K."},{"last_name":"Goedert","first_name":"Debora","full_name":"Goedert, Debora"},{"full_name":"Kokko, Hanna","first_name":"Hanna","last_name":"Kokko"},{"full_name":"Li Richter, Xiang‐Yi","last_name":"Li Richter","first_name":"Xiang‐Yi"},{"full_name":"Moodie, Iain R.","last_name":"Moodie","first_name":"Iain R."},{"first_name":"Sofie","last_name":"Nilén","full_name":"Nilén, Sofie"},{"last_name":"Olito","first_name":"Colin","full_name":"Olito, Colin"},{"first_name":"Erik I.","last_name":"Svensson","full_name":"Svensson, Erik I."},{"first_name":"Peter","last_name":"Czuppon","full_name":"Czuppon, Peter"},{"last_name":"Connallon","first_name":"Tim","full_name":"Connallon, Tim"}],"issue":"2","_id":"20655","has_accepted_license":"1","oa":1,"intvolume":"       101","ddc":["570"],"external_id":{"isi":["001614285900001"],"pmid":["41235821 "]},"language":[{"iso":"eng"}],"das_tickbox":"0"},{"corr_author":"1","article_type":"original","date_created":"2026-02-12T10:13:02Z","scopus_import":"1","day":"01","tmp":{"short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"type":"journal_article","acknowledgement":"This article is based on chapter 5 of the PhD thesis of A. Casallas. The authors thank Graziano Giuliani for discussions on the boundary-condition experiments. A. Casallas was supported by a PhD fellowship awarded by the Abdus Salam International Centre for Theoretical Physics. A. Casallas also acknowledges support by the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 101034413. C. Muller acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). The authors gratefully acknowledge Daniel Hernández-Deckers, Lokahith Agasthya, Chris Holloway, and Paolina Cerlini for their valuable feedback and insightful discussions. They are especially thankful to Bety Pechacova for suggesting the use of SHAP to complement their analysis. They also thank the two anonymous reviewers for their constructive comments, which improved the quality and clarity of the article significantly. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"},{"name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","_id":"629205d8-2b32-11ec-9570-e1356ff73576","grant_number":"805041","call_identifier":"H2020"}],"citation":{"short":"A. Casallas Garcia, A. Mark Tompkins, C.J. Muller, Quarterly Journal of the Royal Meteorological Society 152 (2026).","apa":"Casallas Garcia, A., Mark Tompkins, A., &#38; Muller, C. J. (2026). Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>","ieee":"A. Casallas Garcia, A. Mark Tompkins, and C. J. Muller, “Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events,” <i>Quarterly Journal of the Royal Meteorological Society</i>, vol. 152, no. 777. Wiley, 2026.","ista":"Casallas Garcia A, Mark Tompkins A, Muller CJ. 2026. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society. 152(777), e70131.","ama":"Casallas Garcia A, Mark Tompkins A, Muller CJ. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. <i>Quarterly Journal of the Royal Meteorological Society</i>. 2026;152(777). doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>","chicago":"Casallas Garcia, Alejandro, Adrian Mark Tompkins, and Caroline J Muller. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>. Wiley, 2026. <a href=\"https://doi.org/10.1002/qj.70131\">https://doi.org/10.1002/qj.70131</a>.","mla":"Casallas Garcia, Alejandro, et al. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” <i>Quarterly Journal of the Royal Meteorological Society</i>, vol. 152, no. 777, e70131, Wiley, 2026, doi:<a href=\"https://doi.org/10.1002/qj.70131\">10.1002/qj.70131</a>."},"OA_place":"publisher","OA_type":"hybrid","status":"public","publication":"Quarterly Journal of the Royal Meteorological Society","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication_identifier":{"issn":["0035-9009"],"eissn":["1477-870X"]},"quality_controlled":"1","article_number":"e70131","oa_version":"Published Version","title":"Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events","ec_funded":1,"date_published":"2026-04-01T00:00:00Z","volume":152,"year":"2026","month":"04","publisher":"Wiley","fulldoi":"https://doi.org/10.1002/qj.70131","supplementarymaterial":"yes","date_updated":"2026-07-27T11:10:50Z","file":[{"file_size":11133215,"checksum":"3edd5dee1459dcf62973ae501270be8c","access_level":"open_access","date_updated":"2026-07-27T11:09:24Z","content_type":"application/pdf","file_id":"22419","creator":"dernst","success":1,"relation":"main_file","file_name":"2026_QuarterlyJourRoyalMeteorolSoc_Casallas.pdf","date_created":"2026-07-27T11:09:24Z"}],"file_date_updated":"2026-07-27T11:09:24Z","language":[{"iso":"eng"}],"das_tickbox":"1","oa":1,"has_accepted_license":"1","intvolume":"       152","ddc":["550"],"issue":"777","_id":"21217","author":[{"last_name":"Casallas Garcia","orcid":"0000-0002-1988-5035","first_name":"Alejandro","id":"92081129-2d75-11ef-a48d-b04dd7a2385a","full_name":"Casallas Garcia, Alejandro"},{"full_name":"Mark Tompkins, Adrian","last_name":"Mark Tompkins","first_name":"Adrian"},{"full_name":"Muller, Caroline J","first_name":"Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","orcid":"0000-0001-5836-5350","last_name":"Muller"}],"doi":"10.1002/qj.70131","dataavailabilitystatement":"The data that support the findings of this study are available from the corresponding author, Alejandro Casallas, upon reasonable request.","department":[{"_id":"CaMu"}],"abstract":[{"lang":"eng","text":"This study investigates the mechanisms driving clustered convection and the breakdown of the Intertropical Convergence Zone (ITCZ) over the Western Pacific Warm Pool using high‐resolution cloud‐resolving simulations and machine‐learning sensitivity experiments. Results show that ITCZ breakdown episodes, marked by spatially homogeneous convection and weakened meridional moisture gradients, are triggered primarily by anomalous moisture advection linked to the equatorial Rossby‐wave activity. While large‐scale moisture advection regulates the background convective state strongly, it is the surface and low‐level meridional winds that dominate transitions between clustered and random convection. Simulations demonstrate that moisture alone can sustain convective clustering, but breakdown episodes are more persistent and widespread when coupled with southerly meridional advection. These findings confirm that wave‐driven advection acts as a regulatory mechanism, periodically disrupting convective clustering and reshaping the meridional moisture gradient. This modulation of organization by wave‐induced breakdown events is critical for understanding tropical convection variability and its implications for the climate system."}],"article_processing_charge":"Yes (via OA deal)","researchdata_availability":"upon request"},{"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2507.11387","open_access":"1"}],"supplementarymaterial":"no","fulldoi":"https://doi.org/10.1142/S0218202526410010","year":"2026","publisher":"World Scientific Publishing","month":"06","volume":36,"date_updated":"2026-07-27T12:11:38Z","_id":"21504","issue":"6","intvolume":"        36","oa":1,"language":[{"iso":"eng"}],"das_tickbox":"0","external_id":{"arxiv":["2507.11387"]},"researchdata_availability":"no","article_processing_charge":"No","department":[{"_id":"JaMa"}],"abstract":[{"lang":"eng","text":"Selecting an appropriate divergence measure is a critical aspect of machine learning, as it directly impacts model performance. Among the most widely used, we find the Kullback–Leibler (KL) divergence, originally introduced in kinetic theory as a measure of relative entropy between probability distributions. Just as in machine learning, the ability to quantify the proximity of probability distributions plays a central role in kinetic theory. In this paper, we present a comparative review of divergence measures rooted in kinetic theory, highlighting their theoretical foundations and exploring their potential applications in machine learning and artificial intelligence."}],"doi":"10.1142/S0218202526410010","author":[{"full_name":"Auricchio, Gennaro","last_name":"Auricchio","first_name":"Gennaro"},{"last_name":"Brigati","id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1","first_name":"Giovanni","full_name":"Brigati, Giovanni"},{"full_name":"Giudici, Paolo","first_name":"Paolo","last_name":"Giudici"},{"full_name":"Toscani, Giuseppe","first_name":"Giuseppe","last_name":"Toscani"}],"page":"1185-1233","type":"journal_article","scopus_import":"1","day":"01","date_created":"2026-03-29T22:07:08Z","arxiv":1,"article_type":"original","citation":{"ama":"Auricchio G, Brigati G, Giudici P, Toscani G. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. 2026;36(6):1185-1233. doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>","chicago":"Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>.","mla":"Auricchio, Gennaro, et al. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>, vol. 36, no. 6, World Scientific Publishing, 2026, pp. 1185–233, doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>.","short":"G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and Methods in Applied Sciences 36 (2026) 1185–1233.","apa":"Auricchio, G., Brigati, G., Giudici, P., &#38; Toscani, G. (2026). From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>","ieee":"G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties,” <i>Mathematical Models and Methods in Applied Sciences</i>, vol. 36, no. 6. World Scientific Publishing, pp. 1185–1233, 2026.","ista":"Auricchio G, Brigati G, Giudici P, Toscani G. 2026. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. Mathematical Models and Methods in Applied Sciences. 36(6), 1185–1233."},"project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"acknowledgement":"This work has been written within the activities of GNCS and GNFM groups of INdAM (Italian\r\nNational Institute of High Mathematics). G.B. has been funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 101034413. P.G. has been funded by the European Union - NextGenerationEU, in the framework of the GRINSGrowing Resilient, INclusive and Sustainable (GRINS PE00000018).","mathsc":["35B40","35L60","35K55","35Q70","35Q91","35Q92"],"publication_identifier":{"eissn":["1793-6314"],"issn":["0218-2025"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publication":"Mathematical Models and Methods in Applied Sciences","status":"public","OA_type":"green","OA_place":"repository","date_published":"2026-06-01T00:00:00Z","ec_funded":1,"title":"From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties","oa_version":"Preprint","quality_controlled":"1"},{"page":"931-940","author":[{"full_name":"Olmeda, Fabrizio","last_name":"Olmeda","id":"69dbf5fb-8a76-11ed-866b-fb486d8b5689","first_name":"Fabrizio"},{"full_name":"Lohoff, Tim","first_name":"Tim","last_name":"Lohoff"},{"full_name":"Kafetzopoulos, Ioannis","first_name":"Ioannis","last_name":"Kafetzopoulos"},{"full_name":"Clark, Stephen J.","first_name":"Stephen J.","last_name":"Clark"},{"full_name":"Benson, Laura","first_name":"Laura","last_name":"Benson"},{"full_name":"Santos, Fatima","first_name":"Fatima","last_name":"Santos"},{"last_name":"Krueger","first_name":"Felix","full_name":"Krueger, Felix"},{"first_name":"Simon","last_name":"Walker","full_name":"Walker, Simon"},{"first_name":"Wolf","last_name":"Reik","full_name":"Reik, Wolf"},{"full_name":"Rulands, Steffen","last_name":"Rulands","first_name":"Steffen"}],"doi":"10.1038/s41567-026-03263-x","dataavailabilitystatement":"All sequencing datasets reported in this paper are available on Gene Expression Omnibus (GEO) under accession GSE166226. STORM localization data are available on Zenodo (https://doi.org/10.5281/zenodo.18965309)57. Raw images are available upon request. Code for computing the correlation functions and STORM analysis are available via GitHub at https://github.com/srulands/inference_of_spatio-temporal_processes.","abstract":[{"text":"The development of complex tissues relies on the precise assignment of cell identity. At the molecular scale, this process depends on the deposition of epigenetic modifications—such as methylation—that are regulated by complex biochemical networks and occur at specific regions on the DNA and chromatin. Here we show that despite the complexity of epigenetic regulation, dynamical scaling and self-similarity of DNA methylation marks emerge in embryonic development. Drawing on single-cell multi-omics experiments, super-resolution microscopy and statistical physics, we demonstrate that these phenomena originate in dynamical feedback between DNA methylation and the formation of nanoscale dynamic chromatin aggregates. These nanoscale processes lead to genome-wide increase in DNA methylation marks following a power law and self-similar correlation functions. Using this framework, we identify methylation patterns that precede gene expression changes in embryonic symmetry breaking. Our work identifies linear sequencing measurements as a laboratory to study mesoscopic biophysical processes in vivo.","lang":"eng"}],"department":[{"_id":"EdHa"}],"article_processing_charge":"Yes (via OA deal)","researchdata_availability":"yes","external_id":{"pmid":["42318073"]},"das_tickbox":"1","language":[{"iso":"eng"}],"intvolume":"        22","has_accepted_license":"1","oa":1,"ddc":["570"],"_id":"21849","date_updated":"2026-07-27T13:56:09Z","file":[{"date_created":"2026-07-27T13:54:58Z","success":1,"relation":"main_file","file_name":"2026_NaturePhysics_Olmeda.pdf","content_type":"application/pdf","file_id":"22591","creator":"dernst","date_updated":"2026-07-27T13:54:58Z","access_level":"open_access","file_size":7932222,"checksum":"58e7734f1ebaf6def642140cb489f08f"}],"file_date_updated":"2026-07-27T13:54:58Z","volume":22,"month":"06","publisher":"Springer Nature","year":"2026","pmid":1,"supplementarymaterial":"yes","fulldoi":"https://doi.org/10.1038/s41567-026-03263-x","PlanS_conform":"1","quality_controlled":"1","title":"Scaling and self-similarity in the formation of the embryonic epigenome","oa_version":"Published Version","ec_funded":1,"date_published":"2026-06-01T00:00:00Z","OA_place":"publisher","OA_type":"hybrid","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Nature Physics","publication_status":"published","publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"acknowledgement":"We thank all members of the W.R. and S.R. laboratories, F. Piazza, B. D. Simons, and F. Jülicher for helpful discussions. We thank M. Ciarchi for providing annotations for the chromatin compartments. S.R. is a member of the Center for Nano Science (CeNS). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement number 950349). Research in W.R.’s laboratory was supported by the Biotechnology and Biological Sciences Research Council (BB/K010867/1), Wellcome (095645/Z/11/Z) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (EpiCell lineage 882798). F.O. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement number 101034413. Open access funding provided by Max Planck Society.","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413"}],"citation":{"ama":"Olmeda F, Lohoff T, Kafetzopoulos I, et al. Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. 2026;22:931-940. doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>","mla":"Olmeda, Fabrizio, et al. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>, vol. 22, Springer Nature, 2026, pp. 931–40, doi:<a href=\"https://doi.org/10.1038/s41567-026-03263-x\">10.1038/s41567-026-03263-x</a>.","chicago":"Olmeda, Fabrizio, Tim Lohoff, Ioannis Kafetzopoulos, Stephen J. Clark, Laura Benson, Fatima Santos, Felix Krueger, Simon Walker, Wolf Reik, and Steffen Rulands. “Scaling and Self-Similarity in the Formation of the Embryonic Epigenome.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>.","apa":"Olmeda, F., Lohoff, T., Kafetzopoulos, I., Clark, S. J., Benson, L., Santos, F., … Rulands, S. (2026). Scaling and self-similarity in the formation of the embryonic epigenome. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-026-03263-x\">https://doi.org/10.1038/s41567-026-03263-x</a>","short":"F. Olmeda, T. Lohoff, I. Kafetzopoulos, S.J. Clark, L. Benson, F. Santos, F. Krueger, S. Walker, W. Reik, S. Rulands, Nature Physics 22 (2026) 931–940.","ista":"Olmeda F, Lohoff T, Kafetzopoulos I, Clark SJ, Benson L, Santos F, Krueger F, Walker S, Reik W, Rulands S. 2026. Scaling and self-similarity in the formation of the embryonic epigenome. Nature Physics. 22, 931–940.","ieee":"F. Olmeda <i>et al.</i>, “Scaling and self-similarity in the formation of the embryonic epigenome,” <i>Nature Physics</i>, vol. 22. Springer Nature, pp. 931–940, 2026."},"article_type":"original","scopus_import":"1","date_created":"2026-05-10T22:02:16Z","day":"01","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"type":"journal_article"}]