[{"type":"journal_article","file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_updated":"2025-04-16T09:36:08Z","checksum":"25d9bd490719b45eca84f4d93a06c69f","file_size":839510,"file_id":"19578","file_name":"2025_MathProgramming_Dvorak.pdf","date_created":"2025-04-16T09:36:08Z","content_type":"application/pdf","success":1}],"oa":1,"keyword":["minimum 0-extension problem","metric labeling problem","discrete metric spaces","metric extensions","computational complexity","valued constraint satisfaction problems","discrete convex analysis","L-convex functions"],"date_created":"2021-09-27T10:48:23Z","abstract":[{"text":"Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem}, denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai: if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed a theory of discrete convex functions on orientable modular graphs generalizing several known classes of functions in discrete convex analysis, such as L♮-convex functions. We consider a more general version of the problem in which unary functions fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where set F⊆(V2) is fixed. We extend the complexity classification above by providing an explicit condition on (μ,F) for the problem to be tractable. In order to prove the tractability part, we generalize Hirai's theory and define a larger class of discrete convex functions. It covers, in particular, another well-known class of functions, namely submodular functions on an integer lattice. Finally, we improve the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n","lang":"eng"}],"status":"public","quality_controlled":"1","arxiv":1,"corr_author":"1","article_type":"original","page":"279-322","scopus_import":"1","day":"01","doi":"10.1007/s10107-024-02064-5","year":"2025","author":[{"full_name":"Dvorak, Martin","id":"40ED02A8-C8B4-11E9-A9C0-453BE6697425","orcid":"0000-0001-5293-214X","last_name":"Dvorak","first_name":"Martin"},{"first_name":"Vladimir","last_name":"Kolmogorov","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","full_name":"Kolmogorov, Vladimir"}],"title":"Generalized minimum 0-extension problem and discrete convexity","month":"01","ddc":["004"],"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"isi":1,"acknowledgement":"We thank the anonymous reviewers for their careful reading of our manuscript and their many insightful comments and suggestions. Open access funding provided by Institute of Science and Technology (IST Austria).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2025-04-16T09:36:08Z","intvolume":"       209","license":"https://creativecommons.org/licenses/by/4.0/","publication":"Mathematical Programming","volume":209,"date_published":"2025-01-01T00:00:00Z","oa_version":"Published Version","publisher":"Springer Nature","publication_status":"published","has_accepted_license":"1","OA_place":"publisher","OA_type":"hybrid","language":[{"iso":"eng"}],"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"citation":{"chicago":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>.","ieee":"M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and discrete convexity,” <i>Mathematical Programming</i>, vol. 209. Springer Nature, pp. 279–322, 2025.","mla":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>, vol. 209, Springer Nature, 2025, pp. 279–322, doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>.","ama":"Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. 2025;209:279-322. doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>","ista":"Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and discrete convexity. Mathematical Programming. 209, 279–322.","short":"M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322.","apa":"Dvorak, M., &#38; Kolmogorov, V. (2025). Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>"},"publication_identifier":{"issn":["0025-5610"],"eissn":["1436-4646"]},"external_id":{"isi":["001176563300001"],"arxiv":["2109.10203"]},"_id":"10045","article_processing_charge":"Yes (via OA deal)","date_updated":"2025-05-19T13:52:10Z"},{"author":[{"first_name":"Oliver","last_name":"Sieberling","full_name":"Sieberling, Oliver"},{"full_name":"Kuznedelev, Denis","first_name":"Denis","last_name":"Kuznedelev"},{"first_name":"Eldar","last_name":"Kurtic","id":"47beb3a5-07b5-11eb-9b87-b108ec578218","full_name":"Kurtic, Eldar"},{"full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian","last_name":"Alistarh"}],"year":"2025","day":"01","scopus_import":"1","page":"55556-55590","ddc":["000"],"month":"05","title":"EvoPress: Accurate dynamic model compression via evolutionary search","abstract":[{"text":"The high computational costs of large language models (LLMs) have led to a flurry of research on LLM compression, via methods such as quantization, sparsification, or structured pruning. A new frontier in this area is given by dynamic, non-uniform compression methods, which adjust the compression levels (e.g., sparsity) per-block or even per-layer in order to minimize accuracy loss, while guaranteeing a global compression threshold. Yet, current methods rely on estimating the \"importance\" of a given layer, implicitly assuming that layers contribute independently to the overall compression error. We begin from the motivating observation that this independence assumption does not generally hold for LLM compression: pruning a model further may even significantly recover performance. To address this, we propose EvoPress, a novel evolutionary framework for dynamic LLM compression. By formulating dynamic compression as a general optimization problem, EvoPress identifies optimal compression profiles in a highly efficient manner, and generalizes across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art performance for dynamic compression of Llama, Mistral, and Phi models, setting new benchmarks for structural pruning (block/layer dropping), unstructured sparsity, and quantization with dynamic bitwidths.","lang":"eng"}],"date_created":"2025-12-14T23:02:05Z","file":[{"success":1,"file_name":"2025_ICML_Sieberling.pdf","date_created":"2025-12-16T12:32:40Z","content_type":"application/pdf","access_level":"open_access","creator":"dernst","date_updated":"2025-12-16T12:32:40Z","relation":"main_file","file_id":"20828","checksum":"1d744fbaeb199b08e8b6f48bc0dd047e","file_size":908379}],"oa":1,"type":"conference","corr_author":"1","quality_controlled":"1","arxiv":1,"status":"public","external_id":{"arxiv":["2410.14649"]},"citation":{"ieee":"O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate dynamic model compression via evolutionary search,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.","chicago":"Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In <i>42nd International Conference on Machine Learning</i>, 267:55556–90. ML Research Press, 2025.","ista":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate dynamic model compression via evolutionary search. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 55556–55590.","short":"O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590.","mla":"Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 55556–90.","ama":"Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic model compression via evolutionary search. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:55556-55590.","apa":"Sieberling, O., Kuznedelev, D., Kurtic, E., &#38; Alistarh, D.-A. (2025). EvoPress: Accurate dynamic model compression via evolutionary search. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 55556–55590). Vancouver, Canada: ML Research Press."},"publication_identifier":{"eissn":["2640-3498"]},"department":[{"_id":"DaAl"}],"OA_type":"gold","language":[{"iso":"eng"}],"OA_place":"publisher","has_accepted_license":"1","date_updated":"2025-12-16T12:34:32Z","article_processing_charge":"No","_id":"20820","publication":"42nd International Conference on Machine Learning","intvolume":"       267","file_date_updated":"2025-12-16T12:32:40Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","alternative_title":["PMLR"],"conference":{"end_date":"2025-07-19","name":"ICML: International Conference on Machine Learning","location":"Vancouver, Canada","start_date":"2025-07-13"},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_status":"published","publisher":"ML Research Press","oa_version":"Published Version","date_published":"2025-05-01T00:00:00Z","volume":267},{"year":"2025","author":[{"last_name":"Nguyen","first_name":"Anh Duc","full_name":"Nguyen, Anh Duc"},{"id":"D0CF4148-C985-11E9-8066-0BDEE5697425","full_name":"Markov, Ilia","first_name":"Ilia","last_name":"Markov"},{"full_name":"Wu, Frank Zhengqing","last_name":"Wu","first_name":"Frank Zhengqing"},{"full_name":"Ramezani-Kebrya, Ali","last_name":"Ramezani-Kebrya","first_name":"Ali"},{"last_name":"Antonakopoulos","first_name":"Kimon","full_name":"Antonakopoulos, Kimon"},{"last_name":"Alistarh","first_name":"Dan-Adrian","orcid":"0000-0003-3650-940X","full_name":"Alistarh, Dan-Adrian","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Volkan","last_name":"Cevher","full_name":"Cevher, Volkan"}],"project":[{"grant_number":"101158077","_id":"8e35c14b-16d5-11f0-9cad-a3fc35339161","name":"FastML: Efficient and Cost-Effective Distributed Machine Learning"}],"scopus_import":"1","page":"46026-46072","day":"01","ddc":["000"],"month":"05","title":"Layer-wise quantization for quantized optimistic dual averaging","abstract":[{"lang":"eng","text":"Modern deep neural networks exhibit heterogeneity across numerous layers of various types such as residuals, multi-head attention, etc., due to varying structures (dimensions, activation functions, etc.), distinct representation characteristics, which impact predictions. We develop a general layer-wise quantization framework with tight variance and code-length bounds, adapting to the heterogeneities over the course of training. We then apply a new layer-wise quantization technique within distributed variational inequalities (VIs), proposing a novel Quantized Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which achieves competitive convergence rates for monotone VIs. We empirically show that QODA achieves up to a 150% speedup over the baselines in end-to-end training time for training Wasserstein GAN on 12+GPUs."}],"date_created":"2025-12-14T23:02:06Z","oa":1,"file":[{"file_id":"20830","file_size":756213,"checksum":"a7edf0e4304171a3e035842b3aab1704","date_updated":"2025-12-16T12:45:41Z","creator":"dernst","access_level":"open_access","relation":"main_file","success":1,"date_created":"2025-12-16T12:45:41Z","content_type":"application/pdf","file_name":"2025_ICML_Nguyen.pdf"}],"type":"conference","arxiv":1,"quality_controlled":"1","status":"public","external_id":{"arxiv":["2505.14371"]},"department":[{"_id":"DaAl"}],"citation":{"chicago":"Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya, Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” In <i>42nd International Conference on Machine Learning</i>, 267:46026–72. ML Research Press, 2025.","ieee":"A. D. Nguyen <i>et al.</i>, “Layer-wise quantization for quantized optimistic dual averaging,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 46026–46072.","ama":"Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic dual averaging. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:46026-46072.","mla":"Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual Averaging.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 46026–72.","short":"A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A. Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 46026–46072.","ista":"Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 46026–46072.","apa":"Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos, K., Alistarh, D.-A., &#38; Cevher, V. (2025). Layer-wise quantization for quantized optimistic dual averaging. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press."},"publication_identifier":{"eissn":["2640-3498"]},"has_accepted_license":"1","OA_type":"gold","OA_place":"publisher","language":[{"iso":"eng"}],"article_processing_charge":"No","date_updated":"2025-12-16T12:46:54Z","_id":"20821","publication":"42nd International Conference on Machine Learning","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       267","file_date_updated":"2025-12-16T12:45:41Z","conference":{"end_date":"2025-07-19","start_date":"2025-07-13","location":"Vancouver, Canada","name":"ICML: International Conference on Machine Learning"},"acknowledgement":"This work was supported by Hasler Foundation Program: Hasler Responsible AI (project number 21043). The research was also sponsored by the Army Research Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011. We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS) for providing computing resources. Dan Alistarh and Ilia Markov were supported in part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian Centre for knowledge-driven machine learning under\r\nproject number 332645 - and its Centre for Research-based Innovation funding scheme (Visual Intelligence under grant no. 309439).","alternative_title":["PMLR"],"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publisher":"ML Research Press","publication_status":"published","oa_version":"Published Version","volume":267,"date_published":"2025-05-01T00:00:00Z"},{"oa_version":"Preprint","date_published":"2025-12-05T00:00:00Z","volume":16271,"publication_status":"published","publisher":"Springer Nature","acknowledgement":"Jesko Dujmovic: Funded by the European Union (ERC, LACONIC, 101041207). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them.\r\nChristoph U. Günther and Krzysztof Pietrzak: This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.","alternative_title":["LNCS"],"conference":{"end_date":"2025-12-05","start_date":"2025-12-01","location":"Aarhus, Denmark","name":"TCC: Theory of Cryptography"},"publication":"23rd International Conference on Theory of Cryptography","intvolume":"     16271","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-12-29T11:44:16Z","article_processing_charge":"No","_id":"20844","OA_type":"green","language":[{"iso":"eng"}],"OA_place":"repository","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783032122896"]},"citation":{"ista":"Dujmovic J, Günther CU, Pietrzak KZ. 2025. Space-deniable proofs. 23rd International Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol. 16271, 171–202.","short":"J. Dujmovic, C.U. Günther, K.Z. Pietrzak, in:, 23rd International Conference on Theory of Cryptography, Springer Nature, 2025, pp. 171–202.","mla":"Dujmovic, Jesko, et al. “Space-Deniable Proofs.” <i>23rd International Conference on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 171–202, doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">10.1007/978-3-032-12290-2_6</a>.","ama":"Dujmovic J, Günther CU, Pietrzak KZ. Space-deniable proofs. In: <i>23rd International Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:171-202. doi:<a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">10.1007/978-3-032-12290-2_6</a>","apa":"Dujmovic, J., Günther, C. U., &#38; Pietrzak, K. Z. (2025). Space-deniable proofs. In <i>23rd International Conference on Theory of Cryptography</i> (Vol. 16271, pp. 171–202). Aarhus, Denmark: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">https://doi.org/10.1007/978-3-032-12290-2_6</a>","ieee":"J. Dujmovic, C. U. Günther, and K. Z. Pietrzak, “Space-deniable proofs,” in <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark, 2025, vol. 16271, pp. 171–202.","chicago":"Dujmovic, Jesko, Christoph Ullrich Günther, and Krzysztof Z Pietrzak. “Space-Deniable Proofs.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:171–202. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-3-032-12290-2_6\">https://doi.org/10.1007/978-3-032-12290-2_6</a>."},"department":[{"_id":"KrPi"}],"quality_controlled":"1","status":"public","corr_author":"1","oa":1,"type":"conference","abstract":[{"lang":"eng","text":"We introduce and construct a new proof system called Non-interactive Arguments of Knowledge or Space (NArKoS), where a space-bounded prover can convince a verifier they know a secret, while having access to sufficient space allows one to forge indistinguishable proofs without the secret.\r\nAn application of NArKoS are space-deniable proofs, which are proofs of knowledge (say for authentication in access control) that are sound when executed by a lightweight device like a smart-card or an RFID chip that cannot have much storage, but are deniable (in the strong sense of online deniability) as the verifier, like a card reader, can efficiently forge such proofs.\r\nWe construct NArKoS in the random oracle model using an OR-proof combining a sigma protocol (for the proof of knowledge of the secret) with a new proof system called simulatable Proof of Transient Space (simPoTS). We give two different constructions of simPoTS, one based on labelling graphs with high pebbling complexity, a technique used in the construction of memory-hard functions and proofs of space, and a more practical construction based on the verifiable space-hard functions from TCC’24 where a prover must compute a root of a sparse polynomial. In both cases, the main challenge is making the proofs efficiently simulatable."}],"main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2025/1723"}],"date_created":"2025-12-21T23:01:33Z","month":"12","title":"Space-deniable proofs","author":[{"last_name":"Dujmovic","first_name":"Jesko","full_name":"Dujmovic, Jesko"},{"last_name":"Günther","first_name":"Christoph Ullrich","id":"ec98511c-eb8e-11eb-b029-edd25d7271a1","full_name":"Günther, Christoph Ullrich"},{"last_name":"Pietrzak","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654","full_name":"Pietrzak, Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87"}],"project":[{"name":"Security and Privacy by Design for Complex Systems","grant_number":"F8509","_id":"34a34d57-11ca-11ed-8bc3-a2688a8724e1"}],"doi":"10.1007/978-3-032-12290-2_6","year":"2025","day":"05","scopus_import":"1","page":"171-202"},{"file_date_updated":"2025-12-29T11:15:42Z","intvolume":"       112","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Physical Review E","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"This research was funded in whole or in part by the Austrian Science Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant\r\nAgreement No. 949120). This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge the crucial contributions of Alexandre Morin in getting the project off the ground, and Jack Merrin for creating the SU-8 deposition protocol used in the construction of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their work on single-particle characterization. ","publication_status":"published","publisher":"American Physical Society","volume":112,"date_published":"2025-12-01T00:00:00Z","ec_funded":1,"oa_version":"Published Version","publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"citation":{"chicago":"Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>.","ieee":"E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter,” <i>Physical Review E</i>, vol. 112, no. 6. American Physical Society, 2025.","ama":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. 2025;112(6). doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>","mla":"Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic Active Matter.” <i>Physical Review E</i>, vol. 112, no. 6, 065418, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/1ss8-31rb\">10.1103/1ss8-31rb</a>.","short":"E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical Review E 112 (2025).","ista":"Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical Review E. 112(6), 065418.","apa":"Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., &#38; Waitukaitis, S. R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/1ss8-31rb\">https://doi.org/10.1103/1ss8-31rb</a>"},"department":[{"_id":"ScWa"}],"external_id":{"arxiv":["2508.05643"]},"OA_type":"hybrid","OA_place":"publisher","language":[{"iso":"eng"}],"has_accepted_license":"1","issue":"6","_id":"20847","date_updated":"2025-12-29T11:19:34Z","article_processing_charge":"Yes (via OA deal)","date_created":"2025-12-21T23:01:34Z","abstract":[{"lang":"eng","text":"We report on an experimental active matter system with motion restricted to four cardinal directions. Our particles are magnetite-doped colloidal spheres driven by the Quincke electrorotational instability. The absence of a magnetic field (|𝑩|=0) leads to circular trajectories interspersed with short spontaneous runs. Intermediate fields (|𝑩|≲20mT) linearize the motion along the axis perpendicular to 𝑩. At high magnetic fields, we observe the surprising emergence of a second, distinct linearization along the axis parallel to 𝑩. With numerical simulations, we show that this behavior can be explained by anisotropic magnetic susceptibility."}],"type":"journal_article","oa":1,"file":[{"success":1,"file_name":"2025_PhysReviewE_Fitzgerald.pdf","content_type":"application/pdf","date_created":"2025-12-29T11:15:42Z","file_id":"20862","checksum":"d593e933f976c3f3cde37ad66539d57d","file_size":2131491,"creator":"dernst","access_level":"open_access","date_updated":"2025-12-29T11:15:42Z","relation":"main_file"}],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"corr_author":"1","status":"public","arxiv":1,"quality_controlled":"1","day":"01","scopus_import":"1","author":[{"full_name":"Fitzgerald, Eavan","id":"2df8ab8f-080d-11ed-979a-bfe651ca3afa","last_name":"Fitzgerald","first_name":"Eavan"},{"last_name":"Clavaud","first_name":"Cécile","orcid":"0000-0002-1843-3803","full_name":"Clavaud, Cécile","id":"5f654c5d-04a1-11eb-ab36-ba9ffec58bd8"},{"full_name":"Das, Debasish","first_name":"Debasish","last_name":"Das"},{"full_name":"Lenton, Isaac C","id":"a550210f-223c-11ec-8182-e2d45e817efb","last_name":"Lenton","first_name":"Isaac C","orcid":"0000-0002-5010-6984"},{"first_name":"Scott R","last_name":"Waitukaitis","orcid":"0000-0002-2299-3176","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","full_name":"Waitukaitis, Scott R"}],"project":[{"_id":"bd8eede5-d553-11ed-ba76-eaded0d13485","grant_number":"E 298","name":"MixQUIckR: Mixing with QUIncke Rollers"},{"_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa","call_identifier":"H2020","grant_number":"949120","name":"Tribocharge: a multi-scale approach to an enduring problem in physics"}],"year":"2025","doi":"10.1103/1ss8-31rb","article_type":"original","article_number":"065418","ddc":["530"],"PlanS_conform":"1","title":"Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active matter","month":"12"},{"oa_version":"Published Version","date_published":"2025-12-12T00:00:00Z","publication_status":"epub_ahead","publisher":"Wiley","acknowledgement":"This work was supported by the European Commission-financed project IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This research was supported by the Scientific Service Units (SSU) of the Institute of Science and Technology Austria (ISTA) through resources provided by the Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H. acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033 and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Advanced Science","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-12-29T10:15:43Z","article_processing_charge":"Yes","_id":"20851","language":[{"iso":"eng"}],"OA_place":"publisher","OA_type":"gold","has_accepted_license":"1","publication_identifier":{"eissn":["2198-3844"]},"citation":{"chicago":"Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez, Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>.","ieee":"X. Chang <i>et al.</i>, “Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications,” <i>Advanced Science</i>. Wiley, 2025.","ama":"Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. 2025. doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>","mla":"Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>, e15962, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/advs.202515962\">10.1002/advs.202515962</a>.","ista":"Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez M, Biendicho JJ, Cabot A. 2025. Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced Science., e15962.","short":"X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca, M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science (2025).","apa":"Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot, A. (2025). Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. Wiley. <a href=\"https://doi.org/10.1002/advs.202515962\">https://doi.org/10.1002/advs.202515962</a>"},"department":[{"_id":"MaIb"}],"quality_controlled":"1","status":"public","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"type":"journal_article","abstract":[{"text":"High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material for high power density in lithium-ion batteries. However, it suffers from poor cycle life associated with the rock-salt phase transformation. This study presents a straightforward synthesis approach to enhance the electrochemical performance of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4, and, more importantly, effectively mitigates the formation of the rock-salt phase, thereby enhancing structural stability, as confirmed by operando X-ray absorption spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C, 2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode and a high-loading cathode exhibit excellent cycling performance. They retain 80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9 V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and thereby enhancing their potential for practical applications.","lang":"eng"}],"date_created":"2025-12-21T23:01:35Z","month":"12","title":"Mitigating the rock-salt phase transformation in disordered LNMO through synergetic solid-state AlF3/LiF modifications","ddc":["540"],"PlanS_conform":"1","article_number":"e15962","article_type":"original","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"author":[{"full_name":"Chang, Xingqi","last_name":"Chang","first_name":"Xingqi"},{"full_name":"Escudero, Carlos","last_name":"Escudero","first_name":"Carlos"},{"first_name":"Ashley P.","last_name":"Black","full_name":"Black, Ashley P."},{"full_name":"Horta, Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","first_name":"Sharona"},{"first_name":"Elías","last_name":"Martínez","full_name":"Martínez, Elías"},{"full_name":"Lu, Xuan","last_name":"Lu","first_name":"Xuan"},{"first_name":"Jordi","last_name":"Llorca","full_name":"Llorca, Jordi"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","first_name":"Maria"},{"first_name":"Jordi Jacas","last_name":"Biendicho","full_name":"Biendicho, Jordi Jacas"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"}],"doi":"10.1002/advs.202515962","year":"2025","day":"12","DOAJ_listed":"1","scopus_import":"1"},{"pmid":1,"department":[{"_id":"KrCh"}],"citation":{"chicago":"Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2524109122\">https://doi.org/10.1073/pnas.2524109122</a>.","ieee":"J. Svoboda and K. Chatterjee, “Promoters of cooperation in evolutionary games,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 51. National Academy of Sciences, p. e2524109122, 2025.","apa":"Svoboda, J., &#38; Chatterjee, K. (2025). Promoters of cooperation in evolutionary games. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2524109122\">https://doi.org/10.1073/pnas.2524109122</a>","mla":"Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary Games.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 51, National Academy of Sciences, 2025, p. e2524109122, doi:<a href=\"https://doi.org/10.1073/pnas.2524109122\">10.1073/pnas.2524109122</a>.","ama":"Svoboda J, Chatterjee K. Promoters of cooperation in evolutionary games. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(51):e2524109122. doi:<a href=\"https://doi.org/10.1073/pnas.2524109122\">10.1073/pnas.2524109122</a>","ista":"Svoboda J, Chatterjee K. 2025. Promoters of cooperation in evolutionary games. Proceedings of the National Academy of Sciences. 122(51), e2524109122.","short":"J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences 122 (2025) e2524109122."},"publication_identifier":{"eissn":["1091-6490"]},"external_id":{"pmid":["41397136"]},"has_accepted_license":"1","OA_place":"publisher","language":[{"iso":"eng"}],"OA_type":"hybrid","issue":"51","_id":"20857","article_processing_charge":"Yes (in subscription journal)","date_updated":"2026-02-16T12:34:04Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       122","file_date_updated":"2025-12-29T09:36:50Z","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","publication":"Proceedings of the National Academy of Sciences","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"acknowledgement":"J.S. and K.C. were supported by the European Research Council CoG 863818 (ForM-SMArt) and Austrian Science Fund (FWF) 10.55776/COE12.","publisher":"National Academy of Sciences","publication_status":"published","volume":122,"date_published":"2025-12-15T00:00:00Z","oa_version":"Published Version","ec_funded":1,"page":"e2524109122","scopus_import":"1","day":"15","doi":"10.1073/pnas.2524109122","year":"2025","project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","grant_number":"863818"}],"author":[{"full_name":"Svoboda, Jakub","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","orcid":"0000-0002-1419-3267","first_name":"Jakub","last_name":"Svoboda"},{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X","first_name":"Krishnendu","last_name":"Chatterjee"}],"article_type":"original","ddc":["000"],"title":"Promoters of cooperation in evolutionary games","month":"12","date_created":"2025-12-28T23:01:26Z","abstract":[{"text":"Evolutionary games provide a flexible mathematical framework for many problems in biology and social evolution. Prisoners’ dilemma, and in particular, the important special case of donation games, represents social dilemmas where cooperation is mutually beneficial, yet defection is preferred by selfish agents. In evolutionary games on networks, the agents interact over a population structure. The existence of population structures that promote cooperative behavior is a fascinating and active research topic. Previous research establishes structures promoting cooperation in the limit of weak selection where the benefit-to-cost ratio β exceeds 1.5. The existence of such structures for medium and strong selection for 1 < ß < 2 and for weak selection for 1 < ß < 1.5 has been a long-standing open question. First, we answer the open questions in the affirmative: For every selection strength and every ß > 1, we construct networks promoting cooperation. Second, we present a robustness result with respect to β and selection strength: Our structures promote cooperation for a range of these parameter values rather than specific parameter values. Finally, we supplement our theoretical results with simulation results on small population structures that show the effectiveness of our construction over well-studied population structures.","lang":"eng"}],"type":"journal_article","file":[{"relation":"main_file","date_updated":"2025-12-29T09:36:50Z","access_level":"open_access","creator":"dernst","file_size":2308124,"checksum":"dd50b62a1efc28c0133fe9c11dbee53c","file_id":"20860","content_type":"application/pdf","date_created":"2025-12-29T09:36:50Z","file_name":"2025_PNAS_Svoboda.pdf","success":1}],"oa":1,"corr_author":"1","status":"public","quality_controlled":"1"},{"scopus_import":"1","day":"04","year":"2025","doi":"10.1016/j.ymthe.2025.10.008","author":[{"last_name":"Rica","first_name":"Ramona","full_name":"Rica, Ramona"},{"full_name":"Klein, Klara","last_name":"Klein","first_name":"Klara"},{"last_name":"Johnson","first_name":"Litty","full_name":"Johnson, Litty"},{"full_name":"Carta, Gabriele","last_name":"Carta","first_name":"Gabriele"},{"last_name":"Sarcevic","first_name":"Mirza","full_name":"Sarcevic, Mirza"},{"id":"3C1BE782-F248-11E8-B48F-1D18A9856A87","full_name":"Langer, Freyja","last_name":"Langer","first_name":"Freyja"},{"full_name":"Rademacher, Christoph","first_name":"Christoph","last_name":"Rademacher"},{"first_name":"Robert","last_name":"Wawrzinek","full_name":"Wawrzinek, Robert"},{"last_name":"Quattrone","first_name":"Federica","full_name":"Quattrone, Federica"},{"full_name":"Sparber, Florian","last_name":"Sparber","first_name":"Florian"}],"article_type":"original","title":"Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response","month":"10","date_created":"2025-12-28T23:01:26Z","main_file_link":[{"url":"https://doi.org/10.1101/2025.05.05.652195","open_access":"1"}],"abstract":[{"lang":"eng","text":"Targeted antigen delivery to immune cells, particularly dendritic cells, has emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while minimizing adverse effects associated with conventional immunization. In this study, we use our previously described small glycomimetic molecule that is selectively recognized by the Langerhans cell (LC)-specific surface receptor Langerin and demonstrate specific delivery of protein antigens to these specialized dendritic cells. Our results show that Langerin-mediated antigen delivery significantly enhances the immune response in vivo, resulting in increased expansion and activation of antigen-specific T cells, compared to immunization with unmodified antigen. We demonstrate the feasibility of our LC-targeted platform for immune cell-specific immunization with protein antigen and underscore the potential of LCs as an access point for next-generation vaccines and immunotherapies."}],"type":"journal_article","oa":1,"status":"public","quality_controlled":"1","department":[{"_id":"PreCl"}],"publication_identifier":{"issn":["1525-0016"],"eissn":["1525-0024"]},"citation":{"ieee":"R. Rica <i>et al.</i>, “Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response,” <i>Molecular Therapy</i>. Elsevier.","chicago":"Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic, Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” <i>Molecular Therapy</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">https://doi.org/10.1016/j.ymthe.2025.10.008</a>.","short":"R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher, R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy (n.d.).","ista":"Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek R, Quattrone F, Sparber F. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. Molecular Therapy.","ama":"Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. <i>Molecular Therapy</i>. doi:<a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">10.1016/j.ymthe.2025.10.008</a>","mla":"Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific Cellular Immune Response.” <i>Molecular Therapy</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">10.1016/j.ymthe.2025.10.008</a>.","apa":"Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber, F. (n.d.). Langerhans cell-targeted protein delivery enhances antigen-specific cellular immune response. <i>Molecular Therapy</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ymthe.2025.10.008\">https://doi.org/10.1016/j.ymthe.2025.10.008</a>"},"language":[{"iso":"eng"}],"OA_place":"repository","OA_type":"green","_id":"20858","article_processing_charge":"No","date_updated":"2025-12-29T09:55:05Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Molecular Therapy","acknowledgement":"This project was generously supported by Seedfinancing (grant no. P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation, und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science and Technology Austria for his continuous technical support.","publisher":"Elsevier","publication_status":"inpress","date_published":"2025-10-04T00:00:00Z","oa_version":"Preprint"},{"publication_status":"epub_ahead","publisher":"Elsevier","oa_version":"Published Version","date_published":"2025-11-04T00:00:00Z","publication":"Developmental Cell","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"The authors would like to acknowledge the Super Resolution Light Microcopy and Nanoscopy (SLN) Facility of ICFO for their support with imaging experiments, Johann Osmond (Nanofabrication laboratory, ICFO) for the design and production of molds for generating confinement coverslip, Merche Rivas for cell culture of immune cells and further support from the CRG Core Facilities for Genomics and Advanced Light Microscopy. We would like to thank Michael Sixt for discussions on this work and the Quidant, Ruprecht, and Wieser lab members for critical reading of the manuscript. This research was supported by the Scientific Service Units (SSU) of IST-Austria through resources provided by the Nanofabrication Facility (NFF). C.A. acknowledges the funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 847517 and V.V. from the ICFOstepstone – PhD Programme funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no 665884. S.W. acknowledges support through the Spanish Ministry of Economy and Competitiveness via MINECO’s Plan Nacional (BFU2017-86296-P). V.R. acknowledges funding from the European Union’s HORIZON-EIC-2021-PATHFINDEROPEN program under grant agreement no. 101046620 and European Union's Horizon Europe program under the grant agreement no. 101072123. E.K. acknowledges funding by a fellowship of the Ministry of Innovation, Science and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2151 – 390873048 and by the TRA Life and Health (University of Bonn) as part of the Excellence Strategy of the federal and state governments.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2025-12-29T09:23:58Z","article_processing_charge":"Yes (in subscription journal)","_id":"20859","external_id":{"pmid":["41192429"]},"publication_identifier":{"issn":["1534-5807"],"eissn":["1878-1551"]},"citation":{"apa":"Company-Garrido, I., Zurita Carpio, A., Colomer-Rosell, M., Ciraulo, B., Molkenbur, R., Lanzerstorfer, P., … Wieser, S. (2025). Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. <i>Developmental Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">https://doi.org/10.1016/j.devcel.2025.10.006</a>","short":"I. Company-Garrido, A. Zurita Carpio, M. Colomer-Rosell, B. Ciraulo, R. Molkenbur, P. Lanzerstorfer, F. Pezzano, C. Agazzi, R. Hauschild, S. Jain, J.M. Jacques, V. Venturini, C. Knapp, Y. Xie, J. Merrin, J. Weghuber, M. Schaaf, R. Quidant, E. Kiermaier, J. Ortega Arroyo, V. Ruprecht, S. Wieser, Developmental Cell (2025).","ista":"Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, Ciraulo B, Molkenbur R, Lanzerstorfer P, Pezzano F, Agazzi C, Hauschild R, Jain S, Jacques JM, Venturini V, Knapp C, Xie Y, Merrin J, Weghuber J, Schaaf M, Quidant R, Kiermaier E, Ortega Arroyo J, Ruprecht V, Wieser S. 2025. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. Developmental Cell.","ama":"Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, et al. Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses. <i>Developmental Cell</i>. 2025. doi:<a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">10.1016/j.devcel.2025.10.006</a>","mla":"Company-Garrido, Iván, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” <i>Developmental Cell</i>, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">10.1016/j.devcel.2025.10.006</a>.","ieee":"I. Company-Garrido <i>et al.</i>, “Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses,” <i>Developmental Cell</i>. Elsevier, 2025.","chicago":"Company-Garrido, Iván, Alberto Zurita Carpio, Mariona Colomer-Rosell, Bernard Ciraulo, Ronja Molkenbur, Peter Lanzerstorfer, Fabio Pezzano, et al. “Myosin II Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.” <i>Developmental Cell</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.devcel.2025.10.006\">https://doi.org/10.1016/j.devcel.2025.10.006</a>."},"department":[{"_id":"Bio"},{"_id":"NanoFab"}],"pmid":1,"OA_place":"publisher","OA_type":"hybrid","language":[{"iso":"eng"}],"has_accepted_license":"1","quality_controlled":"1","status":"public","abstract":[{"text":"Effective immune responses rely on the efficient migration of leukocytes. Yet, how temperature regulates migration dynamics at the single-cell level has remained poorly understood. Using zebrafish embryos and mouse tissue explants, we found that temperature positively regulates leukocyte migration speed, exploration, and arrival frequencies to wounds and lymph vessels. Complementary 2D and 3D cultures revealed that this thermokinetic control of cell migration is conserved across immune cell types, independently of the 3D tissue environment. By applying precise (sub-)cellular temperature modulation, we identified a rapid and reversible thermo-response that depends on myosin II activity. Small physiological increases in temperature (1°C –2°C), as present during fever-like conditions, profoundly increased immune responses by accelerating arrival times at lymphatic vessels and tissue wounds. These findings identify myosin-II-dependent actomyosin contractility as a critical mechanical structure regulating single-cell thermo-adaptability, with physiological implications for tuning the speed of immune responses in vivo.","lang":"eng"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.devcel.2025.10.006","open_access":"1"}],"date_created":"2025-12-28T23:01:27Z","acknowledged_ssus":[{"_id":"NanoFab"}],"oa":1,"type":"journal_article","ddc":["570"],"PlanS_conform":"1","month":"11","title":"Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses","author":[{"full_name":"Company-Garrido, Iván","first_name":"Iván","last_name":"Company-Garrido"},{"full_name":"Zurita Carpio, Alberto","last_name":"Zurita Carpio","first_name":"Alberto"},{"last_name":"Colomer-Rosell","first_name":"Mariona","full_name":"Colomer-Rosell, Mariona"},{"first_name":"Bernard","last_name":"Ciraulo","full_name":"Ciraulo, Bernard"},{"full_name":"Molkenbur, Ronja","first_name":"Ronja","last_name":"Molkenbur"},{"full_name":"Lanzerstorfer, Peter","last_name":"Lanzerstorfer","first_name":"Peter"},{"full_name":"Pezzano, Fabio","first_name":"Fabio","last_name":"Pezzano"},{"full_name":"Agazzi, Costanza","first_name":"Costanza","last_name":"Agazzi"},{"full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9843-3522","first_name":"Robert","last_name":"Hauschild"},{"full_name":"Jain, Saumey","last_name":"Jain","first_name":"Saumey"},{"last_name":"Jacques","first_name":"Jeroen M.","full_name":"Jacques, Jeroen M."},{"full_name":"Venturini, Valeria","last_name":"Venturini","first_name":"Valeria"},{"last_name":"Knapp","first_name":"Christian","full_name":"Knapp, Christian"},{"first_name":"Yufei","last_name":"Xie","full_name":"Xie, Yufei"},{"first_name":"Jack","last_name":"Merrin","orcid":"0000-0001-5145-4609","full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Julian","last_name":"Weghuber","full_name":"Weghuber, Julian"},{"full_name":"Schaaf, Marcel","last_name":"Schaaf","first_name":"Marcel"},{"full_name":"Quidant, Romain","first_name":"Romain","last_name":"Quidant"},{"id":"3EB04B78-F248-11E8-B48F-1D18A9856A87","full_name":"Kiermaier, Eva","first_name":"Eva","last_name":"Kiermaier","orcid":"0000-0001-6165-5738"},{"full_name":"Ortega Arroyo, Jaime","last_name":"Ortega Arroyo","first_name":"Jaime"},{"full_name":"Ruprecht, Verena","id":"4D71A03A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4088-8633","last_name":"Ruprecht","first_name":"Verena"},{"full_name":"Wieser, Stefan","id":"355AA5A0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2670-2217","first_name":"Stefan","last_name":"Wieser"}],"year":"2025","doi":"10.1016/j.devcel.2025.10.006","day":"04","scopus_import":"1","article_type":"original"},{"date_updated":"2026-01-05T12:27:41Z","article_processing_charge":"Yes (via OA deal)","_id":"20866","issue":"4","language":[{"iso":"eng"}],"OA_place":"publisher","OA_type":"hybrid","has_accepted_license":"1","external_id":{"arxiv":["2305.02836"]},"publication_identifier":{"eissn":["1432-0525"],"issn":["0001-5903"]},"citation":{"ista":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025. Hypernode automata. Acta Informatica. 62(4), 43.","short":"E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, Acta Informatica 62 (2025).","mla":"Bartocci, Ezio, et al. “Hypernode Automata.” <i>Acta Informatica</i>, vol. 62, no. 4, 43, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>.","ama":"Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata. <i>Acta Informatica</i>. 2025;62(4). doi:<a href=\"https://doi.org/10.1007/s00236-025-00509-8\">10.1007/s00236-025-00509-8</a>","apa":"Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A. (2025). Hypernode automata. <i>Acta Informatica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>","ieee":"E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode automata,” <i>Acta Informatica</i>, vol. 62, no. 4. Springer Nature, 2025.","chicago":"Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da Costa. “Hypernode Automata.” <i>Acta Informatica</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00236-025-00509-8\">https://doi.org/10.1007/s00236-025-00509-8</a>."},"department":[{"_id":"ToHe"}],"ec_funded":1,"oa_version":"Published Version","volume":62,"date_published":"2025-12-09T00:00:00Z","publication_status":"published","publisher":"Springer Nature","acknowledgement":"This work was supported in part by the Austrian Science Fund (FWF) SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute of Science and Technology (IST Austria).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Acta Informatica","intvolume":"        62","file_date_updated":"2026-01-05T12:26:43Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"12","title":"Hypernode automata","ddc":["000"],"related_material":{"record":[{"relation":"earlier_version","status":"public","id":"14405"}]},"article_number":"43","article_type":"original","project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","call_identifier":"H2020","grant_number":"101020093","name":"Vigilant Algorithmic Monitoring of Software"},{"_id":"34a1b658-11ca-11ed-8bc3-c75229f0241e","grant_number":"F8502","name":"Interface Theory for Security and Privacy"}],"author":[{"full_name":"Bartocci, Ezio","last_name":"Bartocci","first_name":"Ezio"},{"first_name":"Marek","last_name":"Chalupa","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463","full_name":"Chalupa, Marek"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","full_name":"Henzinger, Thomas A","orcid":"0000-0002-2985-7724","last_name":"Henzinger","first_name":"Thomas A"},{"first_name":"Dejan","last_name":"Nickovic","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87","full_name":"Nickovic, Dejan"},{"orcid":"0000-0002-8741-5799","first_name":"Ana","last_name":"Oliveira da Costa","full_name":"Oliveira da Costa, Ana","id":"f347ec37-6676-11ee-b395-a888cb7b4fb4"}],"doi":"10.1007/s00236-025-00509-8","year":"2025","day":"09","scopus_import":"1","arxiv":1,"quality_controlled":"1","status":"public","corr_author":"1","oa":1,"file":[{"file_name":"2025_ActaInformatica_Bartocci.pdf","date_created":"2026-01-05T12:26:43Z","content_type":"application/pdf","success":1,"relation":"main_file","access_level":"open_access","creator":"dernst","date_updated":"2026-01-05T12:26:43Z","checksum":"06ed45a1218ad8464818803ae2968aaf","file_size":7117003,"file_id":"20944"}],"type":"journal_article","abstract":[{"text":"In this work, we present hypernode automata as a specification formalism for hyperproperties of systems whose executions may be misaligned among themselves, such as concurrent systems. These automata consist of nodes labeled with hypernode logic formulas and transitions marked with synchronizing actions. Hypernode logic formulas establish relations between sequences of variable values among different system executions. This logic enables both synchronous and asynchronous analysis of traces. In its asynchronous view on execution traces, hypernode formulas establish relations on the order of value changes for each variable without correlating their timing. In both views, the analysis of different execution traces is synchronized through the transitions of hypernode automata. By combining logic’s declarative nature with automata’s procedural power, hypernode automata seamlessly integrate asynchronicity requirements at the node level with synchronicity between node transitions. We show that the model-checking problem for hypernode automata is decidable for specifications where each node specifies either a synchronous or an asynchronous requirement for the system’s executions, but not both.","lang":"eng"}],"date_created":"2025-12-29T12:07:12Z"},{"abstract":[{"lang":"eng","text":"Residents of low-latitude megacities face growing vulnerability to humid-heat stress under urbanization and global warming, yet limited research has assessed the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat exposures in these cities. Here we quantify the hospital admissions of MBDs in Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat, and project future burdens under various greenhouse gas (GHG)-emission and population scenarios. Humid heat drives a higher morbidity burden than high temperature alone, especially in humid-heat nights. Without population change, the humid-heat-related morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval 56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465 (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing emissions to the lowest pathway. With projected population decline, the attributable hospital admissions will decrease toward century’s end. These findings highlight the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme humid heat."}],"date_created":"2025-12-29T12:11:28Z","type":"journal_article","quality_controlled":"1","status":"public","doi":"10.1038/s44220-025-00519-y","year":"2025","author":[{"last_name":"Liang","first_name":"Chen","full_name":"Liang, Chen"},{"full_name":"Yuan, Jiacan","first_name":"Jiacan","last_name":"Yuan"},{"full_name":"Zhang, Renhe","last_name":"Zhang","first_name":"Renhe"},{"full_name":"Tang, Xu","first_name":"Xu","last_name":"Tang"},{"full_name":"Schumann, Gunter","last_name":"Schumann","first_name":"Gunter"},{"last_name":"Hitchen","first_name":"Esther","full_name":"Hitchen, Esther"},{"full_name":"Polemiti, Elli","last_name":"Polemiti","first_name":"Elli"},{"last_name":"Serin","first_name":"Emin","full_name":"Serin, Emin"},{"last_name":"Kebir","first_name":"Hedi","full_name":"Kebir, Hedi"},{"full_name":"Lett, Tristram A.","first_name":"Tristram A.","last_name":"Lett"},{"first_name":"Nilakshi","last_name":"Vaidya","full_name":"Vaidya, Nilakshi"},{"full_name":"Roy, Jean-Charles","first_name":"Jean-Charles","last_name":"Roy"},{"first_name":"Henrik","last_name":"Walter","full_name":"Walter, Henrik"},{"last_name":"Heinz","first_name":"Andreas","full_name":"Heinz, Andreas"},{"last_name":"Ralser","first_name":"Markus","full_name":"Ralser, Markus"},{"last_name":"Twardziok","first_name":"Sven","full_name":"Twardziok, Sven"},{"full_name":"Eils, Roland","first_name":"Roland","last_name":"Eils"},{"last_name":"Jentsch","first_name":"Marcel","full_name":"Jentsch, Marcel"},{"last_name":"Taron","first_name":"Ulrike-Helene","full_name":"Taron, Ulrike-Helene"},{"last_name":"Schütz","first_name":"Tatjana","full_name":"Schütz, Tatjana"},{"last_name":"Schepanski","first_name":"Kerstin","full_name":"Schepanski, Kerstin"},{"first_name":"Tobias","last_name":"Banaschewski","full_name":"Banaschewski, Tobias"},{"last_name":"Neidhart","first_name":"Maja","full_name":"Neidhart, Maja"},{"first_name":"Andreas","last_name":"Meyer-Lindenberg","full_name":"Meyer-Lindenberg, Andreas"},{"full_name":"Tost, Heike","last_name":"Tost","first_name":"Heike"},{"full_name":"Holz, Nathalie","last_name":"Holz","first_name":"Nathalie"},{"full_name":"Schwarz, Emanuel","first_name":"Emanuel","last_name":"Schwarz"},{"last_name":"Stringaris","first_name":"Argyris","full_name":"Stringaris, Argyris"},{"full_name":"Christmann, Nina","first_name":"Nina","last_name":"Christmann"},{"full_name":"Janson, Karina","first_name":"Karina","last_name":"Janson"},{"first_name":"Frauke","last_name":"Nees","full_name":"Nees, Frauke"},{"full_name":"Neidhart, Maja","last_name":"Neidhart","first_name":"Maja"},{"first_name":"Beke","last_name":"Seefried","full_name":"Seefried, Beke"},{"full_name":"Aden, Rieke","last_name":"Aden","first_name":"Rieke"},{"full_name":"Andreassen, Ole A.","last_name":"Andreassen","first_name":"Ole A."},{"last_name":"Westlye","first_name":"Lars T.","full_name":"Westlye, Lars T."},{"first_name":"Dennis","last_name":"van der Meer","full_name":"van der Meer, Dennis"},{"last_name":"Fernández-Cabello","first_name":"Sara","full_name":"Fernández-Cabello, Sara"},{"full_name":"Kjelkenes, Rikka","first_name":"Rikka","last_name":"Kjelkenes"},{"first_name":"Helga","last_name":"Ask","full_name":"Ask, Helga"},{"full_name":"Rapp, Michael","last_name":"Rapp","first_name":"Michael"},{"last_name":"Tschorn","first_name":"Mira","full_name":"Tschorn, Mira"},{"last_name":"Böttger","first_name":"Sarah Jane","full_name":"Böttger, Sarah Jane"},{"first_name":"Andre","last_name":"Marquand","full_name":"Marquand, Andre"},{"full_name":"Bernas, Antoine","last_name":"Bernas","first_name":"Antoine"},{"first_name":"Gaia","last_name":"Novarino","orcid":"0000-0002-7673-7178","full_name":"Novarino, Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Slater","first_name":"Mel","full_name":"Slater, Mel"},{"full_name":"Gallego, Jaime","first_name":"Jaime","last_name":"Gallego"},{"full_name":"Pastor, Álvaro","last_name":"Pastor","first_name":"Álvaro"},{"full_name":"Feixas, Guillem","first_name":"Guillem","last_name":"Feixas"},{"full_name":"Eiroa-Orosa, Francisco José","last_name":"Eiroa-Orosa","first_name":"Francisco José"},{"full_name":"Nöthen, Markus M.","first_name":"Markus M.","last_name":"Nöthen"},{"full_name":"Forstner, Andreas J.","first_name":"Andreas J.","last_name":"Forstner"},{"last_name":"Claus","first_name":"Isabelle","full_name":"Claus, Isabelle"},{"full_name":"Mathey, Carina","last_name":"Mathey","first_name":"Carina"},{"full_name":"Heilmann-Heimbach, Stefanie","last_name":"Heilmann-Heimbach","first_name":"Stefanie"},{"first_name":"Per","last_name":"Hoffmann","full_name":"Hoffmann, Per"},{"full_name":"Miller, Abigail","last_name":"Miller","first_name":"Abigail"},{"full_name":"Sommer, Peter","first_name":"Peter","last_name":"Sommer"},{"first_name":"Karen","last_name":"Schmitt","full_name":"Schmitt, Karen"},{"last_name":"Wilbertz","first_name":"Johannes","full_name":"Wilbertz, Johannes"},{"first_name":"Myrto","last_name":"Patraskaki","full_name":"Patraskaki, Myrto"},{"first_name":"Viktor","last_name":"Jirsa","full_name":"Jirsa, Viktor"},{"last_name":"Petkoski","first_name":"Spase","full_name":"Petkoski, Spase"},{"full_name":"Athanasiadis, Anastasios-Polykarpos","last_name":"Athanasiadis","first_name":"Anastasios-Polykarpos"},{"full_name":"Spanlang, Bernhard","last_name":"Spanlang","first_name":"Bernhard"},{"full_name":"Pearmund, Charlie","last_name":"Pearmund","first_name":"Charlie"},{"full_name":"Hese, Sören","last_name":"Hese","first_name":"Sören"},{"full_name":"Renner, Paul","first_name":"Paul","last_name":"Renner"},{"full_name":"Jia, Tianye","first_name":"Tianye","last_name":"Jia"},{"first_name":"Xiao","last_name":"Chang","full_name":"Chang, Xiao"},{"first_name":"Yuxiang","last_name":"Dai","full_name":"Dai, Yuxiang"},{"last_name":"Xia","first_name":"Yunman","full_name":"Xia, Yunman"},{"full_name":"Li, Yuzhu","first_name":"Yuzhu","last_name":"Li"},{"full_name":"Zhang, Yanqing","last_name":"Zhang","first_name":"Yanqing"},{"last_name":"Calhoun","first_name":"Vince","full_name":"Calhoun, Vince"},{"full_name":"Thompson, Paul","last_name":"Thompson","first_name":"Paul"},{"full_name":"Clinton, Nicholas","first_name":"Nicholas","last_name":"Clinton"},{"full_name":"Desrivières, Sylvane","first_name":"Sylvane","last_name":"Desrivières"},{"first_name":"Kofoworola","last_name":"Agunbiade","full_name":"Agunbiade, Kofoworola"},{"full_name":"Yu, Xinyang","last_name":"Yu","first_name":"Xinyang"},{"full_name":"Zhang, Zuo","first_name":"Zuo","last_name":"Zhang"},{"full_name":"Chen, Di","last_name":"Chen","first_name":"Di"},{"first_name":"Allan H.","last_name":"Young","full_name":"Young, Allan H."},{"first_name":"Ameli","last_name":"Schwalber","full_name":"Schwalber, Ameli"},{"full_name":"Köhler, Vanessa","first_name":"Vanessa","last_name":"Köhler"},{"full_name":"Stahl, Bernd","first_name":"Bernd","last_name":"Stahl"},{"first_name":"George","last_name":"Ogoh","full_name":"Ogoh, George"},{"last_name":"Schikowski","first_name":"Tamara","full_name":"Schikowski, Tamara"},{"last_name":"Brandlistuen","first_name":"Ragnhild","full_name":"Brandlistuen, Ragnhild"}],"project":[{"grant_number":"101057429","_id":"349d1832-11ca-11ed-8bc3-d79b574010e0","name":"Reducing the impact of major environmental challenges on mental health"}],"scopus_import":"1","page":"1532-1544","day":"01","article_type":"original","month":"12","title":"Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai","publication":"Nature Mental Health","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"         3","acknowledgement":"This research was supported by the National Natural Science Foundation of China (grants 42288101 and 42175066) and Shanghai International Science and Technology Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554), the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.","publisher":"Springer Nature","publication_status":"published","oa_version":"None","date_published":"2025-12-01T00:00:00Z","volume":3,"department":[{"_id":"GaNo"}],"publication_identifier":{"issn":["2731-6076"]},"citation":{"short":"C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti, E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser, S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski, M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris, N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen, L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M. Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater, J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner, I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer, K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis, B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia, Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade, X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh, T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544.","ista":"Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N, Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G, Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S, Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V, Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T, Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. Nature Mental Health. 3(12), 1532–1544.","ama":"Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. 2025;3(12):1532-1544. doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>","mla":"Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:<a href=\"https://doi.org/10.1038/s44220-025-00519-y\">10.1038/s44220-025-00519-y</a>.","apa":"Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen, R. (2025). Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>","ieee":"C. Liang <i>et al.</i>, “Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai,” <i>Nature Mental Health</i>, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025.","chicago":"Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental Health</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s44220-025-00519-y\">https://doi.org/10.1038/s44220-025-00519-y</a>."},"language":[{"iso":"eng"}],"OA_type":"closed access","issue":"12","article_processing_charge":"No","date_updated":"2026-01-05T12:02:29Z","_id":"20868"},{"_id":"20869","article_processing_charge":"No","date_updated":"2026-01-05T11:56:22Z","issue":"12","OA_type":"closed access","language":[{"iso":"eng"}],"department":[{"_id":"NiBa"}],"pmid":1,"publication_identifier":{"issn":["0002-9122"],"eissn":["1537-2197"]},"citation":{"apa":"Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., &#38; Baskett, C. (2025). Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. Wiley. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>","ama":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. <i>American Journal of Botany</i>. 2025;112(12). doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>","mla":"Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>, vol. 112, no. 12, e70129, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/ajb2.70129\">10.1002/ajb2.70129</a>.","ista":"Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors. American Journal of Botany. 112(12), e70129.","short":"A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of Botany 112 (2025).","chicago":"Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett. “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American Journal of Botany</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/ajb2.70129\">https://doi.org/10.1002/ajb2.70129</a>.","ieee":"A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors,” <i>American Journal of Botany</i>, vol. 112, no. 12. Wiley, 2025."},"external_id":{"pmid":["41327576 "]},"volume":112,"date_published":"2025-12-01T00:00:00Z","oa_version":"None","ec_funded":1,"publisher":"Wiley","publication_status":"published","acknowledgement":"Thank you to Doug Schemske and Nick Barton forcritically reviewing the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for their thoughtfulcomments and suggestions, which substantially improved the clarity and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon 2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement No. 754411","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       112","publication":"American Journal of Botany","title":"Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors","month":"12","related_material":{"link":[{"relation":"software","url":"https://github.com/Alex-Fuster/hybrids_drought"}]},"article_type":"original","article_number":"e70129","scopus_import":"1","day":"01","doi":"10.1002/ajb2.70129","year":"2025","project":[{"grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships"}],"author":[{"full_name":"Fuster‐Calvo, Alexandre","last_name":"Fuster‐Calvo","first_name":"Alexandre"},{"full_name":"Jaworski, Coline C.","first_name":"Coline C.","last_name":"Jaworski"},{"full_name":"Ellis, Thomas","id":"3153D6D4-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas","last_name":"Ellis","orcid":"0000-0002-8511-0254"},{"first_name":"Carina","last_name":"Baskett","orcid":"0000-0002-7354-8574","id":"3B4A7CE2-F248-11E8-B48F-1D18A9856A87","full_name":"Baskett, Carina"}],"status":"public","quality_controlled":"1","type":"journal_article","date_created":"2025-12-29T12:14:26Z","abstract":[{"lang":"eng","text":"Premise: What maintains trait divergence in the face of gene flow? Two varieties of wild snapdragon (Antirrhinum majus) characterized by divergent flower color hybridize in their native range. Selection on flower color genes is indicated by sharp clines, but the selective agents have not been demonstrated. Although previous work has focused on pollinators, pigmentation genes can also contribute to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates stress tolerance, which could contribute to hybrid zone maintenance through parental niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus, yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods: We experimentally compared drought tolerance of each morphotype from allopatric crosses within and between varieties using three greenhouse treatments. Control plants were watered as needed, while drought-treated plants were watered half as often, either from the transplant stage (“early” drought), or from flowering onset (“late” drought).\r\nResults: Parental morphotypes responded identically to drought in fitness and most phenotypic traits. However, hybrids had lower survival (14%) under late drought stress than parental morphotypes (70%). All hybrids that flowered in the late drought treatment died, compared to ~20% of flowering parental morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially contribute to flower color divergence in the face of gene flow in A. majus. Further research should test the relevance of our results to field conditions and explicitly probe the role of flower color genes in drought tolerance."}]},{"article_processing_charge":"Yes (via OA deal)","date_updated":"2026-01-05T11:22:25Z","_id":"20925","has_accepted_license":"1","OA_place":"publisher","language":[{"iso":"eng"}],"OA_type":"hybrid","external_id":{"pmid":["41459414"]},"pmid":1,"department":[{"_id":"LaEr"}],"citation":{"ista":"Erdös L, Henheik SJ, Vogel C. 2025. Normal typicality and dynamical typicality for a random block-band matrix model. Letters in Mathematical Physics. 116, 5.","short":"L. Erdös, S.J. Henheik, C. Vogel, Letters in Mathematical Physics 116 (2025).","mla":"Erdös, László, et al. “Normal Typicality and Dynamical Typicality for a Random Block-Band Matrix Model.” <i>Letters in Mathematical Physics</i>, vol. 116, 5, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s11005-025-02037-5\">10.1007/s11005-025-02037-5</a>.","ama":"Erdös L, Henheik SJ, Vogel C. Normal typicality and dynamical typicality for a random block-band matrix model. <i>Letters in Mathematical Physics</i>. 2025;116. doi:<a href=\"https://doi.org/10.1007/s11005-025-02037-5\">10.1007/s11005-025-02037-5</a>","apa":"Erdös, L., Henheik, S. J., &#38; Vogel, C. (2025). Normal typicality and dynamical typicality for a random block-band matrix model. <i>Letters in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11005-025-02037-5\">https://doi.org/10.1007/s11005-025-02037-5</a>","ieee":"L. Erdös, S. J. Henheik, and C. Vogel, “Normal typicality and dynamical typicality for a random block-band matrix model,” <i>Letters in Mathematical Physics</i>, vol. 116. Springer Nature, 2025.","chicago":"Erdös, László, Sven Joscha Henheik, and Cornelia Vogel. “Normal Typicality and Dynamical Typicality for a Random Block-Band Matrix Model.” <i>Letters in Mathematical Physics</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s11005-025-02037-5\">https://doi.org/10.1007/s11005-025-02037-5</a>."},"publication_identifier":{"issn":["0377-9017"],"eissn":["1573-0530"]},"oa_version":"Published Version","ec_funded":1,"date_published":"2025-12-26T00:00:00Z","volume":116,"publisher":"Springer Nature","publication_status":"epub_ahead","acknowledgement":"L.E. and J.H. are supported by the ERC Advanced Grant “RMTBeyond” No. 101020331. Moreover, J.H. acknowledges (partial) financial support by the ERC Consolidator Grant “ProbQuant” (jointly with the Swiss State Secretariat for Education, Research and Innovation). C.V. was (partially) supported by the German Academic Scholarship Foundation and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – TRR 352 – Project-ID 470903074. Moreover, C.V. acknowledges (partial) financial support by the ERC Starting Grant “FermiMath\" No. 101040991 and the ERC Consolidator Grant “RAMBAS” No. 10104424, funded by the European Union. Open access funding provided by Institute of Science and Technology (IST Austria).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"Letters in Mathematical Physics","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       116","month":"12","title":"Normal typicality and dynamical typicality for a random block-band matrix model","PlanS_conform":"1","ddc":["510"],"article_number":"5","article_type":"original","year":"2025","doi":"10.1007/s11005-025-02037-5","author":[{"full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","first_name":"László","last_name":"Erdös"},{"first_name":"Sven Joscha","last_name":"Henheik","orcid":"0000-0003-1106-327X","full_name":"Henheik, Sven Joscha","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb"},{"id":"1cd0554a-ea28-11f0-9f40-ff76440883cd","full_name":"Vogel, Cornelia","first_name":"Cornelia","last_name":"Vogel"}],"project":[{"name":"Random matrices beyond Wigner-Dyson-Mehta","_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020","grant_number":"101020331"}],"scopus_import":"1","day":"26","quality_controlled":"1","status":"public","corr_author":"1","oa":1,"type":"journal_article","main_file_link":[{"url":"https://doi.org/10.1007/s11005-025-02037-5","open_access":"1"}],"abstract":[{"lang":"eng","text":"We prove normal typicality and dynamical typicality for a (centered) random block-band matrix model with block-dependent variances. A key feature of our model is that we achieve intermediate equilibration times, an aspect that has not been proven rigorously in any model before. Our proof builds on recently established concentration estimates for products of resolvents of Wigner type random matrices (Erdős and Riabov in Commun Math Phys 405(12): 282, 2024) and an intricate analysis of the deterministic approximation."}],"date_created":"2026-01-04T23:01:33Z"},{"abstract":[{"text":"Insulin/insulin-like growth factor signaling inhibits FOXO transcription factors to control development, homeostasis, and aging. Here, we use proximity labeling to identify proteins interacting with the C. elegans FOXO DAF-16. We show that in well-fed, unstressed animals harboring active insulin signaling, DAF-16 forms a complex with the PAR-1/MARK serine/threonine kinase, a key regulator of cell polarity. PAR-1 inhibits DAF-16 accumulation and promotes DAF-16 phosphorylation at S249, at a conserved motif that PAR-1/human MARK2 phosphorylates in vitro. DAF-2 insulin-like receptor signaling stimulates DAF-16 S249 phosphorylation, suggesting DAF-2 activates PAR-1. DAF-2 also promotes PAR-1 expression by inhibiting DAF-16. PAR-1 knockdown, or DAF-16 S249A, prolong lifespan, whereas phosphomimetic DAF-16 S249D suppresses the longevity of daf-2 mutants. At low insulin signaling, DAF-16 proximity labeling highlights transcription factors, chromatin regulators, and DNA repair proteins. One interactor, the zinc finger/homeobox protein ZFH-2/ZFHX3, forms a complex with DAF-16 and prolongs lifespan. Our work provides entry points for hypothesis-driven studies of FOXO function and longevity.","lang":"eng"}],"date_created":"2026-01-04T23:01:34Z","file":[{"success":1,"file_name":"2025_NatureComm_Artan.pdf","date_created":"2026-01-05T10:58:28Z","content_type":"application/pdf","creator":"dernst","access_level":"open_access","date_updated":"2026-01-05T10:58:28Z","relation":"main_file","file_id":"20941","checksum":"748e2e003b878b85b6048d51621d6aae","file_size":1642352}],"oa":1,"acknowledged_ssus":[{"_id":"Bio"}],"type":"journal_article","corr_author":"1","quality_controlled":"1","status":"public","author":[{"id":"C407B586-6052-11E9-B3AE-7006E6697425","full_name":"Artan, Murat","first_name":"Murat","last_name":"Artan","orcid":"0000-0001-8945-6992"},{"first_name":"Hanna","last_name":"Schön","id":"C8E17EDC-D7AA-11E9-B7B7-45ECE5697425","full_name":"Schön, Hanna"},{"full_name":"De Bono, Mario","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8347-0443","last_name":"De Bono","first_name":"Mario"}],"project":[{"call_identifier":"H2020","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships"},{"name":"Molecular mechanisms of neural circuit function","_id":"23870BE8-32DE-11EA-91FC-C7463DDC885E","grant_number":"209504/A/17/Z"}],"year":"2025","doi":"10.1038/s41467-025-66409-0","DOAJ_listed":"1","day":"11","scopus_import":"1","article_number":"11355","article_type":"original","ddc":["570"],"PlanS_conform":"1","month":"12","title":"Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins","publication":"Nature Communications","intvolume":"        16","file_date_updated":"2026-01-05T10:58:28Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank de Bono lab members for helpful comments on the manuscript, and the Mass Spec Facility at the Max Perutz Labs, notably WeiQiang Chen and Markus Hartl, for invaluable discussions and comments on mass spec analyses of worm samples. All LC-MS/MS analyses were performed on instruments of the Vienna BioCenter Core Facilities (VBCF). Microscopy was supported by the Scientific Services Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF). We are grateful to Dr. Geraldine Seydoux (Johns Hopkins University) for worm strains and plasmids, and Dr. Seung-Jae V. Lee (KAIST) for RNAi clones. We are grateful to Ekaterina Lashmanova for designing the daf-16::TbID::mNG::3xFLAG knock-in construct and for her outstanding support in the lab. This work was supported by a Wellcome Investigator Award (209504/A/17/Z) to MdB and an ISTplus Fellowship to MA (Marie Sklodowska-Curie agreement No 754411).","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_status":"published","publisher":"Springer Nature","ec_funded":1,"oa_version":"Published Version","date_published":"2025-12-11T00:00:00Z","volume":16,"external_id":{"pmid":["41381452"]},"publication_identifier":{"eissn":["2041-1723"]},"citation":{"short":"M. Artan, H. Schön, M. de Bono, Nature Communications 16 (2025).","ista":"Artan M, Schön H, de Bono M. 2025. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. Nature Communications. 16, 11355.","ama":"Artan M, Schön H, de Bono M. Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>","mla":"Artan, Murat, et al. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>, vol. 16, 11355, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-66409-0\">10.1038/s41467-025-66409-0</a>.","apa":"Artan, M., Schön, H., &#38; de Bono, M. (2025). Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>","ieee":"M. Artan, H. Schön, and M. de Bono, “Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","chicago":"Artan, Murat, Hanna Schön, and Mario de Bono. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-66409-0\">https://doi.org/10.1038/s41467-025-66409-0</a>."},"department":[{"_id":"MaDe"}],"pmid":1,"OA_place":"publisher","OA_type":"gold","language":[{"iso":"eng"}],"has_accepted_license":"1","date_updated":"2026-01-05T11:00:03Z","article_processing_charge":"Yes","_id":"20929"},{"OA_place":"publisher","OA_type":"hybrid","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1097-2765"],"eissn":["1097-4164"]},"citation":{"chicago":"Kelley, Ron, Sagar Khavnekar, Ricardo D. Righetto, Jessica Heebner, Martin Obr, Xianjun Zhang, Saikat Chakraborty, et al. “Toward Community-Driven Visual Proteomics with Large-Scale Cryo-Electron Tomography of Chlamydomonas Reinhardtii.” <i>Molecular Cell</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.molcel.2025.11.029\">https://doi.org/10.1016/j.molcel.2025.11.029</a>.","ieee":"R. Kelley <i>et al.</i>, “Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii,” <i>Molecular Cell</i>. Elsevier.","apa":"Kelley, R., Khavnekar, S., Righetto, R. D., Heebner, J., Obr, M., Zhang, X., … Kotecha, A. (n.d.). Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2025.11.029\">https://doi.org/10.1016/j.molcel.2025.11.029</a>","mla":"Kelley, Ron, et al. “Toward Community-Driven Visual Proteomics with Large-Scale Cryo-Electron Tomography of Chlamydomonas Reinhardtii.” <i>Molecular Cell</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.molcel.2025.11.029\">10.1016/j.molcel.2025.11.029</a>.","ama":"Kelley R, Khavnekar S, Righetto RD, et al. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. <i>Molecular Cell</i>. doi:<a href=\"https://doi.org/10.1016/j.molcel.2025.11.029\">10.1016/j.molcel.2025.11.029</a>","ista":"Kelley R, Khavnekar S, Righetto RD, Heebner J, Obr M, Zhang X, Chakraborty S, Tagiltsev G, Michael AK, Van Dorst S, Waltz F, Mccafferty CL, Lamm L, Zufferey S, Van Der Stappen P, Van Den Hoek H, Wietrzynski W, Harar P, Wan W, Briggs JAG, Plitzko JM, Engel BD, Kotecha A. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell.","short":"R. Kelley, S. Khavnekar, R.D. Righetto, J. Heebner, M. Obr, X. Zhang, S. Chakraborty, G. Tagiltsev, A.K. Michael, S. Van Dorst, F. Waltz, C.L. Mccafferty, L. Lamm, S. Zufferey, P. Van Der Stappen, H. Van Den Hoek, W. Wietrzynski, P. Harar, W. Wan, J.A.G. Briggs, J.M. Plitzko, B.D. Engel, A. Kotecha, Molecular Cell (n.d.)."},"department":[{"_id":"AlMi"}],"_id":"20935","date_updated":"2026-01-05T08:32:47Z","article_processing_charge":"Yes (in subscription journal)","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"Calculations were performed at the Max Planck Institute of Biochemistry and the Raven Supercomputer of the Max Planck Computing and Data Facility (MPCDF) in Garching, Germany; at the sciCORE (http://scicore.unibas.ch/) scientific computing center at the University of Basel, Switzerland; and at Thermo Fisher Scientific, in Eindhoven, the Netherlands. This work was supported by Thermo Fisher Scientific. All lamella preparations and tilt-series collections used in this work were conducted at Thermo Fisher R&D facilities in Brno and Eindhoven, utilizing Arctis and Krios microscopes. This work was also supported by the ERC consolidator grant “cryOcean” (fulfilled by the Swiss State Secretariat for Education, Research and Innovation, M822.00045) as well as a Swiss Nanoscience Institute PhD school grant to B.D.E. and P.V.d.S., an EMBO long-term postdoctoral fellowship (ALTF-383-2022) to G.T., an SNSF Postdoctoral Fellowship (project 210561) to F.W., a Boehringer Ingelheim Fonds fellowship to L.L., and by the Max Planck Society to J.A.G.B. and J.M.P.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Molecular Cell","date_published":"2025-12-19T00:00:00Z","oa_version":"Published Version","publication_status":"inpress","publisher":"Elsevier","article_type":"original","day":"19","scopus_import":"1","author":[{"full_name":"Kelley, Ron","first_name":"Ron","last_name":"Kelley"},{"full_name":"Khavnekar, Sagar","last_name":"Khavnekar","first_name":"Sagar"},{"full_name":"Righetto, Ricardo D.","last_name":"Righetto","first_name":"Ricardo D."},{"full_name":"Heebner, Jessica","last_name":"Heebner","first_name":"Jessica"},{"last_name":"Obr","first_name":"Martin","orcid":"0000-0003-1756-6564","full_name":"Obr, Martin","id":"4741CA5A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Xianjun","last_name":"Zhang","full_name":"Zhang, Xianjun"},{"full_name":"Chakraborty, Saikat","last_name":"Chakraborty","first_name":"Saikat"},{"full_name":"Tagiltsev, Grigory","last_name":"Tagiltsev","first_name":"Grigory"},{"first_name":"Alicia","last_name":"Michael","orcid":"0000-0002-6080-839X","id":"6437c950-2a03-11ee-914d-d6476dd7b75c","full_name":"Michael, Alicia"},{"full_name":"Van Dorst, Sofie","first_name":"Sofie","last_name":"Van Dorst"},{"full_name":"Waltz, Florent","first_name":"Florent","last_name":"Waltz"},{"full_name":"Mccafferty, Caitlyn L.","first_name":"Caitlyn L.","last_name":"Mccafferty"},{"last_name":"Lamm","first_name":"Lorenz","full_name":"Lamm, Lorenz"},{"first_name":"Simon","last_name":"Zufferey","full_name":"Zufferey, Simon"},{"full_name":"Van Der Stappen, Philippe","first_name":"Philippe","last_name":"Van Der Stappen"},{"full_name":"Van Den Hoek, Hugo","first_name":"Hugo","last_name":"Van Den Hoek"},{"full_name":"Wietrzynski, Wojciech","first_name":"Wojciech","last_name":"Wietrzynski"},{"full_name":"Harar, Pavol","id":"e03d953a-6e8c-11ef-99e4-f0717d385cd5","first_name":"Pavol","last_name":"Harar","orcid":"0000-0001-5206-1794"},{"full_name":"Wan, William","last_name":"Wan","first_name":"William"},{"full_name":"Briggs, John A.G.","last_name":"Briggs","first_name":"John A.G."},{"first_name":"Jürgen M.","last_name":"Plitzko","full_name":"Plitzko, Jürgen M."},{"last_name":"Engel","first_name":"Benjamin D.","full_name":"Engel, Benjamin D."},{"full_name":"Kotecha, Abhay","last_name":"Kotecha","first_name":"Abhay"}],"doi":"10.1016/j.molcel.2025.11.029","year":"2025","title":"Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii","month":"12","ddc":["570"],"PlanS_conform":"1","type":"journal_article","oa":1,"date_created":"2026-01-04T23:01:36Z","abstract":[{"text":"In situ cryo-electron tomography (cryo-ET) has emerged as the method of choice to investigate the structures of biomolecules in their native context. However, challenges remain for the efficient production and sharing of large-scale cryo-ET datasets. Here, we combined cryogenic plasma-based focused ion beam (cryo-PFIB) milling with recent advances in cryo-ET acquisition and processing to generate a dataset of 1,829 annotated tomograms of the green alga Chlamydomonas reinhardtii, which we provide as a community resource to drive method development and inspire biological discovery. To assay data quality, we performed subtomogram averaging of both soluble and membrane-bound complexes ranging in size from >3 MDa to ∼200 kDa, including 80S ribosomes, Rubisco, nucleosomes, microtubules, clathrin, photosystem II, and mitochondrial ATP synthase. The majority of these density maps reached sub-nanometer resolution, demonstrating the potential of this C. reinhardtii dataset as well as the promise of modern cryo-ET workflows and open data sharing to empower visual proteomics.","lang":"eng"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.molcel.2025.11.029","open_access":"1"}],"status":"public","quality_controlled":"1"},{"OA_type":"closed access","language":[{"iso":"eng"}],"external_id":{"pmid":["41470065"]},"publication_identifier":{"issn":["1613-6810"],"eissn":["1613-6829"]},"citation":{"mla":"Meng, Weite, et al. “Efficient near Room Temperature Thermoelectric Cooling and Power Generation with CuAgSe.” <i>Small</i>, e13035, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/smll.202513035\">10.1002/smll.202513035</a>.","ama":"Meng W, Li M, Wang Q, et al. Efficient near room temperature thermoelectric cooling and power generation with CuAgSe. <i>Small</i>. 2025. doi:<a href=\"https://doi.org/10.1002/smll.202513035\">10.1002/smll.202513035</a>","short":"W. Meng, M. Li, Q. Wang, P. Song, X. Yang, W.J. Wang, M. Hong, M. Ibáñez, A. Cabot, Y. Zhang, Y. Liu, K.H. Lim, Small (2025).","ista":"Meng W, Li M, Wang Q, Song P, Yang X, Wang WJ, Hong M, Ibáñez M, Cabot A, Zhang Y, Liu Y, Lim KH. 2025. Efficient near room temperature thermoelectric cooling and power generation with CuAgSe. Small., e13035.","apa":"Meng, W., Li, M., Wang, Q., Song, P., Yang, X., Wang, W. J., … Lim, K. H. (2025). Efficient near room temperature thermoelectric cooling and power generation with CuAgSe. <i>Small</i>. Wiley. <a href=\"https://doi.org/10.1002/smll.202513035\">https://doi.org/10.1002/smll.202513035</a>","chicago":"Meng, Weite, Mingquan Li, Qingyue Wang, Pingan Song, Xuan Yang, Wen Jun Wang, Min Hong, et al. “Efficient near Room Temperature Thermoelectric Cooling and Power Generation with CuAgSe.” <i>Small</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/smll.202513035\">https://doi.org/10.1002/smll.202513035</a>.","ieee":"W. Meng <i>et al.</i>, “Efficient near room temperature thermoelectric cooling and power generation with CuAgSe,” <i>Small</i>. Wiley, 2025."},"pmid":1,"department":[{"_id":"MaIb"}],"date_updated":"2026-01-12T09:37:19Z","article_processing_charge":"No","_id":"20973","acknowledgement":"K.H.L. acknowledges financial support from the National Natural Science Foundation of China (NSFC) (Grant Number 22208293) and the National Foreign Expert Project (Y20240175). Y.L. acknowledges funding from the NSFC (Grant Number 22209034), the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province (Grant Number 2022LCX002), and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). Y.Z. acknowledges funding from the NSFC (Grant Number 52502313) and Wenzhou Basic Scientific Research Project (Grant Number G20240034). Q. W. acknowledges financial support from the NSFC (Grant Number 22208292), the High-Level Overseas-Educated Talents Return Program, and the “Pioneer” and “Leading Goose” R&D Program of Zhejiang [2025C04021]. K.H.L., Q. W., and X. Y. also acknowledge the Research Funds of the Institute of Zhejiang University-Quzhou (Grants No. IZQ2022RCZX101, IZQ2021RCZX003, IZQ2021RCZX002, and IZQ2024KJ0004). M.H. acknowledges the funding from the Australian Research Council and the iLAuNCH Trailblazer, Department of Education, Australia. M.H. acknowledges the computational support from the National Computational Infrastructure (NCI), Australia, and Pawsey Supercomputing Centre, Australia.","publication":"Small","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","date_published":"2025-12-30T00:00:00Z","publication_status":"epub_ahead","publisher":"Wiley","article_number":"e13035","article_type":"original","author":[{"last_name":"Meng","first_name":"Weite","full_name":"Meng, Weite"},{"full_name":"Li, Mingquan","last_name":"Li","first_name":"Mingquan"},{"full_name":"Wang, Qingyue","last_name":"Wang","first_name":"Qingyue"},{"first_name":"Pingan","last_name":"Song","full_name":"Song, Pingan"},{"full_name":"Yang, Xuan","last_name":"Yang","first_name":"Xuan"},{"full_name":"Wang, Wen Jun","first_name":"Wen Jun","last_name":"Wang"},{"last_name":"Hong","first_name":"Min","full_name":"Hong, Min"},{"first_name":"Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria"},{"full_name":"Cabot, Andreu","last_name":"Cabot","first_name":"Andreu"},{"last_name":"Zhang","first_name":"Yu","full_name":"Zhang, Yu"},{"first_name":"Yu","last_name":"Liu","full_name":"Liu, Yu"},{"full_name":"Lim, Khak Ho","first_name":"Khak Ho","last_name":"Lim"}],"doi":"10.1002/smll.202513035","year":"2025","day":"30","scopus_import":"1","month":"12","title":"Efficient near room temperature thermoelectric cooling and power generation with CuAgSe","type":"journal_article","abstract":[{"text":"CuAgSe-based materials are attractive for low-temperature thermoelectric (TE) applications but are limited by bipolar conduction and relatively high thermal conductivity. Herein, we report a ligand-free aqueous synthesis of Te-doped CuAgSe (CuAgSe1-xTex), where structural and electronic modulation improve carrier transport and suppress phonon propagation. Ex-situ time-resolved X-ray diffraction reveals a spontaneous growth mechanism, while density functional theory calculations show that Te-5s and 5p orbitals hybridization generates localized states and an asymmetric density of states, thereby enhancing the Seebeck coefficient. Electron microscopy and strain analyses confirm that Te-doping introduces a high density of lattice dislocations and grain boundaries, leading to a reduced lattice thermal conductivity of 0.11 W m−1K−1 at 443 K. These synergistic effects translate into device-level performance—the first integrated CuAgSe thermoelectric modules, exhibit a maximum cooling temperature difference of 27.3 K, and power density of 0.34 W cm−2 with a conversion efficiency of 3.6% at a modest temperature gradient of 136 K. These results demonstrate that CuAgSe1-xTex enables efficient energy harvesting and localized cooling under small temperature gradient, underscoring the importance of structural and electronic design beyond conventional zT benchmarks.","lang":"eng"}],"date_created":"2026-01-11T23:01:34Z","quality_controlled":"1","status":"public"},{"publisher":"Cambridge: Alliance of Diamond Open Access Journals","publication_status":"published","volume":2025,"date_published":"2025-09-01T00:00:00Z","oa_version":"Published Version","ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"      2025","file_date_updated":"2026-02-12T07:50:47Z","publication":"Discrete Analysis","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"Supported by FWF grant (DOI 10.55776/P36278), Supported by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant\r\nAgreement No. 101034413.","_id":"21003","article_processing_charge":"No","date_updated":"2026-02-12T08:03:12Z","department":[{"_id":"TiBr"}],"citation":{"ieee":"T. D. Browning and M. Verzobio, “Counting integer points on affine surfaces with a side condition,” <i>Discrete Analysis</i>, vol. 2025. Cambridge: Alliance of Diamond Open Access Journals, 2025.","chicago":"Browning, Timothy D, and Matteo Verzobio. “Counting Integer Points on Affine Surfaces with a Side Condition.” <i>Discrete Analysis</i>. Cambridge: Alliance of Diamond Open Access Journals, 2025. <a href=\"https://doi.org/10.19086/da.143787\">https://doi.org/10.19086/da.143787</a>.","short":"T.D. Browning, M. Verzobio, Discrete Analysis 2025 (2025).","ista":"Browning TD, Verzobio M. 2025. Counting integer points on affine surfaces with a side condition. Discrete Analysis. 2025, 12.","ama":"Browning TD, Verzobio M. Counting integer points on affine surfaces with a side condition. <i>Discrete Analysis</i>. 2025;2025. doi:<a href=\"https://doi.org/10.19086/da.143787\">10.19086/da.143787</a>","mla":"Browning, Timothy D., and Matteo Verzobio. “Counting Integer Points on Affine Surfaces with a Side Condition.” <i>Discrete Analysis</i>, vol. 2025, 12, Cambridge: Alliance of Diamond Open Access Journals, 2025, doi:<a href=\"https://doi.org/10.19086/da.143787\">10.19086/da.143787</a>.","apa":"Browning, T. D., &#38; Verzobio, M. (2025). Counting integer points on affine surfaces with a side condition. <i>Discrete Analysis</i>. Cambridge: Alliance of Diamond Open Access Journals. <a href=\"https://doi.org/10.19086/da.143787\">https://doi.org/10.19086/da.143787</a>"},"publication_identifier":{"eissn":["2397-3129"]},"external_id":{"arxiv":["2408.11453"]},"has_accepted_license":"1","language":[{"iso":"eng"}],"OA_place":"publisher","OA_type":"diamond","corr_author":"1","status":"public","arxiv":1,"date_created":"2026-01-18T23:02:44Z","abstract":[{"text":"We extend work of Heath-Brown and Salberger, based on the determinant method, to provide a uniform upper bound for the number of integral points of bounded height on an affine surface, which are subject to a polynomial congruence condition. This is applied to get a new uniform bound for points on diagonal quadric surfaces, and to a problem about the representation of integers as a sum of four unlike powers.","lang":"eng"}],"type":"journal_article","oa":1,"file":[{"relation":"main_file","creator":"dernst","access_level":"open_access","date_updated":"2026-02-12T07:50:47Z","checksum":"3d38e850b40f3e1abbfd30073bd4388a","file_size":393625,"file_id":"21214","file_name":"2025_DiscreteAnalysis_Browning.pdf","content_type":"application/pdf","date_created":"2026-02-12T07:50:47Z","success":1}],"ddc":["510"],"title":"Counting integer points on affine surfaces with a side condition","month":"09","scopus_import":"1","day":"01","year":"2025","doi":"10.19086/da.143787","project":[{"name":"Rational curves via function field analytic number theory","grant_number":"P36278","_id":"bd8a4fdc-d553-11ed-ba76-80a0167441a3"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"}],"author":[{"full_name":"Browning, Timothy D","id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","orcid":"0000-0002-8314-0177"},{"id":"7aa8f170-131e-11ed-88e1-a9efd01027cb","full_name":"Verzobio, Matteo","first_name":"Matteo","last_name":"Verzobio","orcid":"0000-0002-0854-0306"}],"article_type":"original","article_number":"12"},{"oa_version":"Published Version","date_published":"2025-10-01T00:00:00Z","volume":21,"publisher":"Association for Computing Machinery","publication_status":"published","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication":"ACM Transactions on Algorithms","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-01-21T09:38:09Z","intvolume":"        21","article_processing_charge":"Yes (via OA deal)","date_updated":"2026-01-21T09:46:26Z","_id":"21007","issue":"4","has_accepted_license":"1","OA_type":"hybrid","OA_place":"publisher","language":[{"iso":"eng"}],"external_id":{"arxiv":["2307.00115"]},"department":[{"_id":"VlKo"}],"citation":{"apa":"Kolmogorov, V. (2025). A simpler and parallelizable O(√log n)-approximation algorithm for SPARSEST CUT. <i>ACM Transactions on Algorithms</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3748723\">https://doi.org/10.1145/3748723</a>","mla":"Kolmogorov, Vladimir. “A Simpler and Parallelizable O(√log n)-Approximation Algorithm for SPARSEST CUT.” <i>ACM Transactions on Algorithms</i>, vol. 21, no. 4, Association for Computing Machinery, 2025, pp. 1–22, doi:<a href=\"https://doi.org/10.1145/3748723\">10.1145/3748723</a>.","ama":"Kolmogorov V. A simpler and parallelizable O(√log n)-approximation algorithm for SPARSEST CUT. <i>ACM Transactions on Algorithms</i>. 2025;21(4):1-22. doi:<a href=\"https://doi.org/10.1145/3748723\">10.1145/3748723</a>","short":"V. Kolmogorov, ACM Transactions on Algorithms 21 (2025) 1–22.","ista":"Kolmogorov V. 2025. A simpler and parallelizable O(√log n)-approximation algorithm for SPARSEST CUT. ACM Transactions on Algorithms. 21(4), 1–22.","chicago":"Kolmogorov, Vladimir. “A Simpler and Parallelizable O(√log n)-Approximation Algorithm for SPARSEST CUT.” <i>ACM Transactions on Algorithms</i>. Association for Computing Machinery, 2025. <a href=\"https://doi.org/10.1145/3748723\">https://doi.org/10.1145/3748723</a>.","ieee":"V. Kolmogorov, “A simpler and parallelizable O(√log n)-approximation algorithm for SPARSEST CUT,” <i>ACM Transactions on Algorithms</i>, vol. 21, no. 4. Association for Computing Machinery, pp. 1–22, 2025."},"publication_identifier":{"eissn":["1549-6333"],"issn":["1549-6325"]},"quality_controlled":"1","arxiv":1,"status":"public","corr_author":"1","file":[{"success":1,"file_name":"2025_ACMToA_Kolmogorov.pdf","content_type":"application/pdf","date_created":"2026-01-21T09:38:09Z","file_id":"21031","checksum":"4a80fdb1e3711b9a2768d2bb8f6d3b4e","file_size":2208302,"access_level":"open_access","creator":"dernst","date_updated":"2026-01-21T09:38:09Z","relation":"main_file"}],"oa":1,"type":"journal_article","abstract":[{"lang":"eng","text":"Currently, the best known tradeoff between approximation ratio and complexity for the Sparsest Cut problem is achieved by the algorithm in [Sherman, FOCS 2009]: it computes O(√(log n)/ε)-approximation using O(nε logO(1) n) maxflows for any ε∈[Θ(1/log n),Θ(1)]. It works by solving the SDP relaxation of [Arora-Rao-Vazirani, STOC 2004] using the Multiplicative Weights Update algorithm (MW) of [Arora-Kale, JACM 2016]. To implement one MW step, Sherman approximately solves a multicommodity flow problem using another application of MW. Nested MW steps are solved via a certain \"chaining\" algorithm that combines results of multiple calls to the maxflow algorithm. We present an alternative approach that avoids solving the multicommodity flow problem and instead computes \"violating paths\". This simplifies Sherman's algorithm by removing a need for a nested application of MW, and also allows parallelization: we show how to compute O(√(log n)/ε)-approximation via O(logO(1) n) maxflows using O(nε) processors. We also revisit Sherman's chaining algorithm, and present a simpler version together with a new analysis."}],"date_created":"2026-01-20T10:04:02Z","month":"10","title":"A simpler and parallelizable O(√log n)-approximation algorithm for SPARSEST CUT","PlanS_conform":"1","ddc":["510"],"related_material":{"record":[{"id":"17236","relation":"shorter_version","status":"public"}]},"article_type":"original","doi":"10.1145/3748723","year":"2025","author":[{"id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov","first_name":"Vladimir"}],"scopus_import":"1","page":"1-22","day":"01"},{"_id":"21016","title":"Identifying cobordisms using kernel persistence","date_updated":"2026-01-21T10:34:57Z","month":"05","article_processing_charge":"No","citation":{"mla":"Bleile, Yossi, et al. “Identifying Cobordisms Using Kernel Persistence.” <i>ArXiv</i>, 2505.17858, doi:<a href=\"https://doi.org/10.48550/arXiv.2505.17858\">10.48550/arXiv.2505.17858</a>.","ama":"Bleile Y, Fajstrup L, Heiss T, Svane AM, Sørensen SS. Identifying cobordisms using kernel persistence. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2505.17858\">10.48550/arXiv.2505.17858</a>","short":"Y. Bleile, L. Fajstrup, T. Heiss, A.M. Svane, S.S. Sørensen, ArXiv (n.d.).","ista":"Bleile Y, Fajstrup L, Heiss T, Svane AM, Sørensen SS. Identifying cobordisms using kernel persistence. arXiv, 2505.17858.","apa":"Bleile, Y., Fajstrup, L., Heiss, T., Svane, A. M., &#38; Sørensen, S. S. (n.d.). Identifying cobordisms using kernel persistence. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2505.17858\">https://doi.org/10.48550/arXiv.2505.17858</a>","chicago":"Bleile, Yossi, Lisbeth Fajstrup, Teresa Heiss, Anne Marie Svane, and Søren Strandskov Sørensen. “Identifying Cobordisms Using Kernel Persistence.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2505.17858\">https://doi.org/10.48550/arXiv.2505.17858</a>.","ieee":"Y. Bleile, L. Fajstrup, T. Heiss, A. M. Svane, and S. S. Sørensen, “Identifying cobordisms using kernel persistence,” <i>arXiv</i>. ."},"day":"23","department":[{"_id":"HeEd"}],"external_id":{"arxiv":["2505.17858"]},"project":[{"name":"Alpha Shape Theory Extended","grant_number":"788183","call_identifier":"H2020","_id":"266A2E9E-B435-11E9-9278-68D0E5697425"}],"author":[{"full_name":"Bleile, Yossi","id":"920a7385-7995-11ef-9bfd-8c434cd8f3c2","orcid":"0000-0002-4861-9174","last_name":"Bleile","first_name":"Yossi"},{"first_name":"Lisbeth","last_name":"Fajstrup","full_name":"Fajstrup, Lisbeth"},{"orcid":"0000-0002-1780-2689","last_name":"Heiss","first_name":"Teresa","id":"4879BB4E-F248-11E8-B48F-1D18A9856A87","full_name":"Heiss, Teresa"},{"full_name":"Svane, Anne Marie","first_name":"Anne Marie","last_name":"Svane"},{"full_name":"Sørensen, Søren Strandskov","last_name":"Sørensen","first_name":"Søren Strandskov"}],"doi":"10.48550/arXiv.2505.17858","year":"2025","language":[{"iso":"eng"}],"OA_place":"repository","article_number":"2505.17858","publication_status":"submitted","status":"public","date_published":"2025-05-23T00:00:00Z","arxiv":1,"ec_funded":1,"oa_version":"Preprint","date_created":"2026-01-20T10:12:21Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Motivated by applications in chemistry, we give a homlogical definition of tunnels, or more generally cobordisms, connecting disjoint parts of a cell complex. For a filtered complex, this defines a persistence module. We give a method for identifying birth and death times using kernel persistence and a matrix reduction algorithm for pairing birth and death times."}],"publication":"arXiv","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2505.17858","open_access":"1"}],"type":"preprint","acknowledgement":"Y. B. B. and L. F. were funded by the Independent Research Fund Denmark, grant\r\nnumber 1026-00037. T. H. was partially supported by the European Research Council\r\n(ERC) Horizon 2020, grant number 788183.","oa":1},{"abstract":[{"text":"In many scientific experiments, the data annotating cost constraints the pace for testing novel hypotheses. Yet, modern machine learning pipelines offer a promising solution—provided their predictions yield correct conclusions. We focus on Prediction-Powered Causal Inferences (PPCI), i.e., estimating the treatment effect in an unlabeled target experiment, relying on training data with the same outcome annotated but potentially different treatment or effect modifiers. We first show that conditional calibration guarantees valid PPCI at population level. Then, we introduce a sufficient representation constraint transferring validity across experiments, which we propose to enforce in practice in Deconfounded Empirical Risk Minimization, our new model-agnostic training objective. We validate our method on synthetic and real-world scientific data, solving impossible problem instances for Empirical Risk Minimization even with standard invariance constraints. In particular, for the first time, we achieve valid causal inference on a scientific experiment with complex recording and no human annotations, fine-tuning a foundational model on our similar annotated experiment.","lang":"eng"}],"date_created":"2026-01-29T14:35:11Z","file":[{"success":1,"content_type":"application/pdf","date_created":"2026-01-29T14:35:02Z","file_name":"17546_Prediction_Powered_Causa.pdf","date_updated":"2026-01-29T14:35:02Z","access_level":"open_access","creator":"flocatel","relation":"main_file","file_id":"21077","file_size":8489023,"checksum":"92467fa566cd36671a6a3b9e71ae0f71"}],"oa":1,"type":"conference","quality_controlled":"1","status":"public","author":[{"last_name":"Cadei","first_name":"Riccardo","full_name":"Cadei, Riccardo","id":"0fa8b76f-72f0-11ef-b75a-a5da96e5ad6b"},{"full_name":"Demirel, Ilker","first_name":"Ilker","last_name":"Demirel"},{"full_name":"De Bartolomeis, Piersilvio","last_name":"De Bartolomeis","first_name":"Piersilvio"},{"full_name":"Lindorfer, Lukas","id":"85f0e6d3-06b3-11ec-8982-8c5049fa4455","first_name":"Lukas","last_name":"Lindorfer"},{"last_name":"Cremer","first_name":"Sylvia","orcid":"0000-0002-2193-3868","full_name":"Cremer, Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Cordelia","last_name":"Schmid","full_name":"Schmid, Cordelia"},{"full_name":"Locatello, Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683","first_name":"Francesco","last_name":"Locatello"}],"year":"2025","day":"15","ddc":["000"],"month":"12","title":"Prediction-powered causal inferences","publication":"39th Annual Conference on Neural Information Processing Systems","intvolume":"        38","file_date_updated":"2026-01-29T14:35:02Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank the Causal Learning and Artificial Intelligence group at ISTA for the continuous feedback on the project and valuable discussions. We thank the Social Immunity group at ISTA, particularly Jinook Oh, for the annotation program and Michaela Hoenigsberger for supporting our ecological experiment. Riccardo Cadei is supported by a Google Research Scholar Award and a Google Initiated Gift to Francesco Locatello. This research was funded in part by the Austrian Science Fund (FWF) 10.55776/COE12). It was further partially supported by the ISTA Interdisciplinary Project Committee for the collaborative project “ALED” between Francesco Locatello and Sylvia Cremer. For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.","alternative_title":["Advances in Neural Information Processing Systems"],"conference":{"start_date":"2025-12-02","name":"NeurIPS: Neural Information Processing Systems","location":"San Diego, CA, United States","end_date":"2025-12-07"},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_status":"epub_ahead","publisher":"Neural Information Processing Systems Foundation","oa_version":"Published Version","date_published":"2025-12-15T00:00:00Z","volume":38,"publication_identifier":{"issn":["1049-5258"]},"citation":{"chicago":"Cadei, Riccardo, Ilker Demirel, Piersilvio De Bartolomeis, Lukas Lindorfer, Sylvia Cremer, Cordelia Schmid, and Francesco Locatello. “Prediction-Powered Causal Inferences.” In <i>39th Annual Conference on Neural Information Processing Systems</i>, Vol. 38. Neural Information Processing Systems Foundation, 2025.","ieee":"R. Cadei <i>et al.</i>, “Prediction-powered causal inferences,” in <i>39th Annual Conference on Neural Information Processing Systems</i>, San Diego, CA, United States, 2025, vol. 38.","mla":"Cadei, Riccardo, et al. “Prediction-Powered Causal Inferences.” <i>39th Annual Conference on Neural Information Processing Systems</i>, vol. 38, Neural Information Processing Systems Foundation, 2025.","ama":"Cadei R, Demirel I, De Bartolomeis P, et al. Prediction-powered causal inferences. In: <i>39th Annual Conference on Neural Information Processing Systems</i>. Vol 38. Neural Information Processing Systems Foundation; 2025.","short":"R. Cadei, I. Demirel, P. De Bartolomeis, L. Lindorfer, S. Cremer, C. Schmid, F. Locatello, in:, 39th Annual Conference on Neural Information Processing Systems, Neural Information Processing Systems Foundation, 2025.","ista":"Cadei R, Demirel I, De Bartolomeis P, Lindorfer L, Cremer S, Schmid C, Locatello F. 2025. Prediction-powered causal inferences. 39th Annual Conference on Neural Information Processing Systems. NeurIPS: Neural Information Processing Systems, Advances in Neural Information Processing Systems, vol. 38.","apa":"Cadei, R., Demirel, I., De Bartolomeis, P., Lindorfer, L., Cremer, S., Schmid, C., &#38; Locatello, F. (2025). Prediction-powered causal inferences. In <i>39th Annual Conference on Neural Information Processing Systems</i> (Vol. 38). San Diego, CA, United States: Neural Information Processing Systems Foundation."},"department":[{"_id":"FrLo"},{"_id":"SyCr"}],"language":[{"iso":"eng"}],"OA_place":"publisher","OA_type":"gold","has_accepted_license":"1","date_updated":"2026-02-16T11:39:33Z","article_processing_charge":"No","_id":"21076"}]
