---
OA_place: publisher
OA_type: hybrid
_id: '19744'
abstract:
- lang: eng
  text: We consider the problem of refuting equivalence of probabilistic programs,
    i.e., the problem of proving that two probabilistic programs induce different
    output distributions. We study this problem in the context of programs with conditioning
    (i.e., with observe and score statements), where the output distribution is conditioned
    by the event that all the observe statements along a run evaluate to true, and
    where the probability densities of different runs may be updated via the score
    statements. Building on a recent work on programs without conditioning, we present
    a new equivalence refutation method for programs with conditioning. Our method
    is based on weighted restarting, a novel transformation of probabilistic programs
    with conditioning to the output equivalent probabilistic programs without conditioning
    that we introduce in this work. Our method is the first to be both a) fully automated,
    and b) providing provably correct answers. We demonstrate the applicability of
    our method on a set of programs from the probabilistic inference literature.
acknowledgement: This work was partially supported by ERC CoG 863818 (ForM-SMArt)
  and Austrian Science Fund (FWF) 10.55776/COE12. Petr Novotný is supported by the
  Czech Science Foundation grant no. GA23-06963S.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Ehsan
  full_name: Kafshdar Goharshadi, Ehsan
  id: 103b4fa0-896a-11ed-bdf8-87b697bef40d
  last_name: Kafshdar Goharshadi
  orcid: 0000-0002-8595-0587
- first_name: Petr
  full_name: Novotný, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotný
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
citation:
  ama: 'Chatterjee K, Goharshady E, Novotný P, Zikelic D. Refuting equivalence in
    probabilistic programs with conditioning. In: <i>31st International Conference
    on Tools and Algorithms for the Construction and Analysis of Systems</i>. Vol
    15697. Springer Nature; 2025:279-300. doi:<a href="https://doi.org/10.1007/978-3-031-90653-4_14">10.1007/978-3-031-90653-4_14</a>'
  apa: 'Chatterjee, K., Goharshady, E., Novotný, P., &#38; Zikelic, D. (2025). Refuting
    equivalence in probabilistic programs with conditioning. In <i>31st International
    Conference on Tools and Algorithms for the Construction and Analysis of Systems</i>
    (Vol. 15697, pp. 279–300). Hamilton, ON, Canada: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-90653-4_14">https://doi.org/10.1007/978-3-031-90653-4_14</a>'
  chicago: Chatterjee, Krishnendu, Ehsan Goharshady, Petr Novotný, and Dorde Zikelic.
    “Refuting Equivalence in Probabilistic Programs with Conditioning.” In <i>31st
    International Conference on Tools and Algorithms for the Construction and Analysis
    of Systems</i>, 15697:279–300. Springer Nature, 2025. <a href="https://doi.org/10.1007/978-3-031-90653-4_14">https://doi.org/10.1007/978-3-031-90653-4_14</a>.
  ieee: K. Chatterjee, E. Goharshady, P. Novotný, and D. Zikelic, “Refuting equivalence
    in probabilistic programs with conditioning,” in <i>31st International Conference
    on Tools and Algorithms for the Construction and Analysis of Systems</i>, Hamilton,
    ON, Canada, 2025, vol. 15697, pp. 279–300.
  ista: 'Chatterjee K, Goharshady E, Novotný P, Zikelic D. 2025. Refuting equivalence
    in probabilistic programs with conditioning. 31st International Conference on
    Tools and Algorithms for the Construction and Analysis of Systems. TACAS: Tools
    and Algorithms for the Construction and Analysis of Systems, LNCS, vol. 15697,
    279–300.'
  mla: Chatterjee, Krishnendu, et al. “Refuting Equivalence in Probabilistic Programs
    with Conditioning.” <i>31st International Conference on Tools and Algorithms for
    the Construction and Analysis of Systems</i>, vol. 15697, Springer Nature, 2025,
    pp. 279–300, doi:<a href="https://doi.org/10.1007/978-3-031-90653-4_14">10.1007/978-3-031-90653-4_14</a>.
  short: K. Chatterjee, E. Goharshady, P. Novotný, D. Zikelic, in:, 31st International
    Conference on Tools and Algorithms for the Construction and Analysis of Systems,
    Springer Nature, 2025, pp. 279–300.
conference:
  end_date: 2025-05-08
  location: Hamilton, ON, Canada
  name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
  start_date: 2025-05-03
corr_author: '1'
date_created: 2025-05-25T22:17:10Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-06-02T11:16:13Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-031-90653-4_14
ec_funded: 1
external_id:
  arxiv:
  - '2501.06579'
file:
- access_level: open_access
  checksum: 7dcd85e7e753bfa994c10b3cf9ebc185
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  creator: dernst
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  date_updated: 2025-06-02T11:13:49Z
  file_id: '19773'
  file_name: 2025_TACAS_Chatterjee_Goharshadi.pdf
  file_size: 532181
  relation: main_file
  success: 1
file_date_updated: 2025-06-02T11:13:49Z
has_accepted_license: '1'
intvolume: '     15697'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Published Version
page: 279-300
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: 31st International Conference on Tools and Algorithms for the Construction
  and Analysis of Systems
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783031906527'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Refuting equivalence in probabilistic programs with conditioning
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15697
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '19771'
abstract:
- lang: eng
  text: "This artifact allows to review and reproduce the Isabelle proofs and practical
    experiments from the paper *Fixed Point Certificates for Reachability and Expected
    Rewards in MDPs*.\r\nThe contents are two-fold:\r\nFirst, the artifact contains
    a formally verified certificate checker for the certificates presented in the
    paper.\r\nThe formal Isabelle/HOL proofs of the background theory can be inspected,
    checked by Isabelle and the code extraction can be retraced.\r\n\r\nSecond, the
    artifact contains a modified version of the model checking tool `Storm` with support
    for certificate generation. Together with the provided scripts and benchmark files,
    this allows to reproduce the experiments from the paper.\r\nAn appropriate subset
    of the experiments is given to allow a review in a timely manner. In addition,
    original logfiles from our experiments are provided, allowing a detailed inspection.\r\n\r\nThe
    package includes convenient installation scripts for [the TACAS 2023 VM](https://doi.org/10.5281/zenodo.7113223)
    (based on Ubuntu 22.04).\r\nA native installation on Linux or macOS systems (including
    the newer ARM-based machines) is also possible."
article_processing_charge: No
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Tim
  full_name: Quatmann, Tim
  last_name: Quatmann
- first_name: Maximilian
  full_name: Schäffeler, Maximilian
  last_name: Schäffeler
- first_name: Maximilian
  full_name: Weininger, Maximilian
  id: 02ab0197-cc70-11ed-ab61-918e71f56881
  last_name: Weininger
- first_name: Tobias
  full_name: Winkler, Tobias
  last_name: Winkler
- first_name: Daniel
  full_name: Zilken, Daniel
  id: d8ebc24a-3f98-11f0-9044-8296d4f39ab3
  last_name: Zilken
citation:
  ama: 'Chatterjee K, Quatmann T, Schäffeler M, Weininger M, Winkler T, Zilken D.
    Artifact: Fixed point certificates for reachability and expected rewards in MDPs.
    2025. doi:<a href="https://doi.org/10.5281/ZENODO.14626585">10.5281/ZENODO.14626585</a>'
  apa: 'Chatterjee, K., Quatmann, T., Schäffeler, M., Weininger, M., Winkler, T.,
    &#38; Zilken, D. (2025). Artifact: Fixed point certificates for reachability and
    expected rewards in MDPs. Zenodo. <a href="https://doi.org/10.5281/ZENODO.14626585">https://doi.org/10.5281/ZENODO.14626585</a>'
  chicago: 'Chatterjee, Krishnendu, Tim Quatmann, Maximilian Schäffeler, Maximilian
    Weininger, Tobias Winkler, and Daniel Zilken. “Artifact: Fixed Point Certificates
    for Reachability and Expected Rewards in MDPs.” Zenodo, 2025. <a href="https://doi.org/10.5281/ZENODO.14626585">https://doi.org/10.5281/ZENODO.14626585</a>.'
  ieee: 'K. Chatterjee, T. Quatmann, M. Schäffeler, M. Weininger, T. Winkler, and
    D. Zilken, “Artifact: Fixed point certificates for reachability and expected rewards
    in MDPs.” Zenodo, 2025.'
  ista: 'Chatterjee K, Quatmann T, Schäffeler M, Weininger M, Winkler T, Zilken D.
    2025. Artifact: Fixed point certificates for reachability and expected rewards
    in MDPs, Zenodo, <a href="https://doi.org/10.5281/ZENODO.14626585">10.5281/ZENODO.14626585</a>.'
  mla: 'Chatterjee, Krishnendu, et al. <i>Artifact: Fixed Point Certificates for Reachability
    and Expected Rewards in MDPs</i>. Zenodo, 2025, doi:<a href="https://doi.org/10.5281/ZENODO.14626585">10.5281/ZENODO.14626585</a>.'
  short: K. Chatterjee, T. Quatmann, M. Schäffeler, M. Weininger, T. Winkler, D. Zilken,
    (2025).
date_created: 2025-06-02T10:13:24Z
date_published: 2025-01-09T00:00:00Z
date_updated: 2025-06-02T10:55:35Z
day: '09'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.5281/ZENODO.14626585
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/ZENODO.14626585
month: '01'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '19743'
    relation: used_in_publication
    status: public
status: public
title: 'Artifact: Fixed point certificates for reachability and expected rewards in
  MDPs'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '19776'
abstract:
- lang: eng
  text: We use the circle method to prove that a density 1 of elements in Fq[t] are
    representable as a sum of three cubes of essentially minimal degree from Fq[t],
    assuming the Ratios Conjecture and that char(Fq)>3. Roughly speaking, to do so,
    we upgrade an order of magnitude result to a full asymptotic formula that was
    conjectured by Hooley in the number field setting.
acknowledgement: We thank Alexandra Florea for discussions on cubic Gauss sums over
  function fields, in addition to the anonymous referee for helpful comments. While
  working on this paper the first two authors were supported by a FWF grant (DOI 10.55776/P36278)
  and the third author was supported by the European Union’s Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.
  Open access funding provided by Institute of Science and Technology (IST Austria).
article_number: '65'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Jakob
  full_name: Glas, Jakob
  id: d6423cba-dc74-11ea-a0a7-ee61689ff5fb
  last_name: Glas
- first_name: Victor
  full_name: Wang, Victor
  id: 76096395-aea4-11ed-a680-ab8ebbd3f1b9
  last_name: Wang
  orcid: 0000-0002-0704-7026
citation:
  ama: Browning TD, Glas J, Wang V. Optimal sums of three cubes in Fq[t]. <i>Mathematische
    Zeitschrift</i>. 2025;310(4). doi:<a href="https://doi.org/10.1007/s00209-025-03765-z">10.1007/s00209-025-03765-z</a>
  apa: Browning, T. D., Glas, J., &#38; Wang, V. (2025). Optimal sums of three cubes
    in Fq[t]. <i>Mathematische Zeitschrift</i>. Springer Nature. <a href="https://doi.org/10.1007/s00209-025-03765-z">https://doi.org/10.1007/s00209-025-03765-z</a>
  chicago: Browning, Timothy D, Jakob Glas, and Victor Wang. “Optimal Sums of Three
    Cubes in Fq[T].” <i>Mathematische Zeitschrift</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s00209-025-03765-z">https://doi.org/10.1007/s00209-025-03765-z</a>.
  ieee: T. D. Browning, J. Glas, and V. Wang, “Optimal sums of three cubes in Fq[t],”
    <i>Mathematische Zeitschrift</i>, vol. 310, no. 4. Springer Nature, 2025.
  ista: Browning TD, Glas J, Wang V. 2025. Optimal sums of three cubes in Fq[t]. Mathematische
    Zeitschrift. 310(4), 65.
  mla: Browning, Timothy D., et al. “Optimal Sums of Three Cubes in Fq[T].” <i>Mathematische
    Zeitschrift</i>, vol. 310, no. 4, 65, Springer Nature, 2025, doi:<a href="https://doi.org/10.1007/s00209-025-03765-z">10.1007/s00209-025-03765-z</a>.
  short: T.D. Browning, J. Glas, V. Wang, Mathematische Zeitschrift 310 (2025).
corr_author: '1'
date_created: 2025-06-03T07:30:21Z
date_published: 2025-05-23T00:00:00Z
date_updated: 2025-09-30T12:43:41Z
day: '23'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1007/s00209-025-03765-z
ec_funded: 1
external_id:
  arxiv:
  - '2408.03668 '
  isi:
  - '001494367000001'
file:
- access_level: open_access
  checksum: 6f71e25740c28257bf89b8bf116c2b4d
  content_type: application/pdf
  creator: dernst
  date_created: 2025-06-03T08:28:14Z
  date_updated: 2025-06-03T08:28:14Z
  file_id: '19782'
  file_name: 2025_MathZeitschrift_Browning.pdf
  file_size: 461622
  relation: main_file
  success: 1
file_date_updated: 2025-06-03T08:28:14Z
has_accepted_license: '1'
intvolume: '       310'
isi: 1
issue: '4'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: bd8a4fdc-d553-11ed-ba76-80a0167441a3
  grant_number: P36278
  name: Rational curves via function field analytic number theory
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Mathematische Zeitschrift
publication_identifier:
  eissn:
  - 1432-1823
  issn:
  - 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal sums of three cubes in Fq[t]
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 310
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '10011'
abstract:
- lang: eng
  text: We propose a new weak solution concept for (two-phase) mean curvature flow
    which enjoys both (unconditional) existence and (weak-strong) uniqueness properties.
    These solutions are evolving varifolds, just as in Brakke's formulation, but are
    coupled to the phase volumes by a simple transport equation. First, we show that,
    in the exact same setup as in Ilmanen's proof [J. Differential Geom. 38, 417-461,
    (1993)], any limit point of solutions to the Allen-Cahn equation is a varifold
    solution in our sense. Second, we prove that any calibrated flow in the sense
    of Fischer et al. [arXiv:2003.05478] - and hence any classical solution to mean
    curvature flow-is unique in the class of our new varifold solutions. This is in
    sharp contrast to the case of Brakke flows, which a priori may disappear at any
    given time and are therefore fatally non-unique. Finally, we propose an extension
    of the solution concept to the multi-phase case which is at least guaranteed to
    satisfy a weak-strong uniqueness principle.
acknowledgement: This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (grant agreement No 948819), and from the Deutsche Forschungsgemeinschaft (DFG,
  German Research Foundation) under Germany’s Excellence Strategy – EXC-2047/1 – 390685813.
  The content of this paper was developed and parts of it were written during a visit
  of the first author to the Hausdorff Center of Mathematics (HCM), University of
  Bonn. The hospitality and the support of HCM are gratefully acknowledged.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sebastian
  full_name: Hensel, Sebastian
  id: 4D23B7DA-F248-11E8-B48F-1D18A9856A87
  last_name: Hensel
  orcid: 0000-0001-7252-8072
- first_name: Tim
  full_name: Laux, Tim
  last_name: Laux
citation:
  ama: 'Hensel S, Laux T. A new varifold solution concept for mean curvature flow:
    Convergence of  the Allen-Cahn equation and weak-strong uniqueness. <i>Journal
    of Differential Geometry</i>. 2025;130:209-268. doi:<a href="https://doi.org/10.4310/jdg/1747065796">10.4310/jdg/1747065796</a>'
  apa: 'Hensel, S., &#38; Laux, T. (2025). A new varifold solution concept for mean
    curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness.
    <i>Journal of Differential Geometry</i>. International Press. <a href="https://doi.org/10.4310/jdg/1747065796">https://doi.org/10.4310/jdg/1747065796</a>'
  chicago: 'Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for
    Mean Curvature Flow: Convergence of  the Allen-Cahn Equation and Weak-Strong Uniqueness.”
    <i>Journal of Differential Geometry</i>. International Press, 2025. <a href="https://doi.org/10.4310/jdg/1747065796">https://doi.org/10.4310/jdg/1747065796</a>.'
  ieee: 'S. Hensel and T. Laux, “A new varifold solution concept for mean curvature
    flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness,” <i>Journal
    of Differential Geometry</i>, vol. 130. International Press, pp. 209–268, 2025.'
  ista: 'Hensel S, Laux T. 2025. A new varifold solution concept for mean curvature
    flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness. Journal
    of Differential Geometry. 130, 209–268.'
  mla: 'Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for Mean
    Curvature Flow: Convergence of  the Allen-Cahn Equation and Weak-Strong Uniqueness.”
    <i>Journal of Differential Geometry</i>, vol. 130, International Press, 2025,
    pp. 209–68, doi:<a href="https://doi.org/10.4310/jdg/1747065796">10.4310/jdg/1747065796</a>.'
  short: S. Hensel, T. Laux, Journal of Differential Geometry 130 (2025) 209–268.
corr_author: '1'
date_created: 2021-09-13T12:17:10Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-05-28T09:27:05Z
day: '01'
department:
- _id: JuFi
doi: 10.4310/jdg/1747065796
ec_funded: 1
external_id:
  arxiv:
  - '2109.04233'
intvolume: '       130'
keyword:
- Mean curvature flow
- gradient flows
- varifolds
- weak solutions
- weak-strong uniqueness
- calibrated geometry
- gradient-flow calibrations
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2109.04233
month: '05'
oa: 1
oa_version: Preprint
page: 209-268
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
  call_identifier: H2020
  grant_number: '948819'
  name: Bridging Scales in Random Materials
publication: Journal of Differential Geometry
publication_identifier:
  eissn:
  - 1945-743X
  issn:
  - 0022-040X
publication_status: published
publisher: International Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A new varifold solution concept for mean curvature flow: Convergence of  the
  Allen-Cahn equation and weak-strong uniqueness'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 130
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10045'
abstract:
- lang: eng
  text: "Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem},
    denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize
    function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative
    costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational
    complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai:
    if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial
    time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed
    a theory of discrete convex functions on orientable modular graphs generalizing
    several known classes of functions in discrete convex analysis, such as L♮-convex
    functions. We consider a more general version of the problem in which unary functions
    fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where
    set F⊆(V2) is fixed. We extend the complexity classification above by providing
    an explicit condition on (μ,F) for the problem to be tractable. In order to prove
    the tractability part, we generalize Hirai's theory and define a larger class
    of discrete convex functions. It covers, in particular, another well-known class
    of functions, namely submodular functions on an integer lattice. Finally, we improve
    the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n"
acknowledgement: We thank the anonymous reviewers for their careful reading of our
  manuscript and their many insightful comments and suggestions. Open access funding
  provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Martin
  full_name: Dvorak, Martin
  id: 40ED02A8-C8B4-11E9-A9C0-453BE6697425
  last_name: Dvorak
  orcid: 0000-0001-5293-214X
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
citation:
  ama: Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete
    convexity. <i>Mathematical Programming</i>. 2025;209:279-322. doi:<a href="https://doi.org/10.1007/s10107-024-02064-5">10.1007/s10107-024-02064-5</a>
  apa: Dvorak, M., &#38; Kolmogorov, V. (2025). Generalized minimum 0-extension problem
    and discrete convexity. <i>Mathematical Programming</i>. Springer Nature. <a href="https://doi.org/10.1007/s10107-024-02064-5">https://doi.org/10.1007/s10107-024-02064-5</a>
  chicago: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension
    Problem and Discrete Convexity.” <i>Mathematical Programming</i>. Springer Nature,
    2025. <a href="https://doi.org/10.1007/s10107-024-02064-5">https://doi.org/10.1007/s10107-024-02064-5</a>.
  ieee: M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and
    discrete convexity,” <i>Mathematical Programming</i>, vol. 209. Springer Nature,
    pp. 279–322, 2025.
  ista: Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and
    discrete convexity. Mathematical Programming. 209, 279–322.
  mla: Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem
    and Discrete Convexity.” <i>Mathematical Programming</i>, vol. 209, Springer Nature,
    2025, pp. 279–322, doi:<a href="https://doi.org/10.1007/s10107-024-02064-5">10.1007/s10107-024-02064-5</a>.
  short: M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322.
corr_author: '1'
date_created: 2021-09-27T10:48:23Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2025-05-19T13:52:10Z
day: '01'
ddc:
- '004'
department:
- _id: GradSch
- _id: VlKo
doi: 10.1007/s10107-024-02064-5
external_id:
  arxiv:
  - '2109.10203'
  isi:
  - '001176563300001'
file:
- access_level: open_access
  checksum: 25d9bd490719b45eca84f4d93a06c69f
  content_type: application/pdf
  creator: dernst
  date_created: 2025-04-16T09:36:08Z
  date_updated: 2025-04-16T09:36:08Z
  file_id: '19578'
  file_name: 2025_MathProgramming_Dvorak.pdf
  file_size: 839510
  relation: main_file
  success: 1
file_date_updated: 2025-04-16T09:36:08Z
has_accepted_license: '1'
intvolume: '       209'
isi: 1
keyword:
- minimum 0-extension problem
- metric labeling problem
- discrete metric spaces
- metric extensions
- computational complexity
- valued constraint satisfaction problems
- discrete convex analysis
- L-convex functions
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 279-322
publication: Mathematical Programming
publication_identifier:
  eissn:
  - 1436-4646
  issn:
  - 0025-5610
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized minimum 0-extension problem and discrete convexity
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 209
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20820'
abstract:
- lang: eng
  text: 'The high computational costs of large language models (LLMs) have led to
    a flurry of research on LLM compression, via methods such as quantization, sparsification,
    or structured pruning. A new frontier in this area is given by dynamic, non-uniform
    compression methods, which adjust the compression levels (e.g., sparsity) per-block
    or even per-layer in order to minimize accuracy loss, while guaranteeing a global
    compression threshold. Yet, current methods rely on estimating the "importance"
    of a given layer, implicitly assuming that layers contribute independently to
    the overall compression error. We begin from the motivating observation that this
    independence assumption does not generally hold for LLM compression: pruning a
    model further may even significantly recover performance. To address this, we
    propose EvoPress, a novel evolutionary framework for dynamic LLM compression.
    By formulating dynamic compression as a general optimization problem, EvoPress
    identifies optimal compression profiles in a highly efficient manner, and generalizes
    across diverse models and compression techniques. Via EvoPress, we achieve state-of-the-art
    performance for dynamic compression of Llama, Mistral, and Phi models, setting
    new benchmarks for structural pruning (block/layer dropping), unstructured sparsity,
    and quantization with dynamic bitwidths.'
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Oliver
  full_name: Sieberling, Oliver
  last_name: Sieberling
- first_name: Denis
  full_name: Kuznedelev, Denis
  last_name: Kuznedelev
- first_name: Eldar
  full_name: Kurtic, Eldar
  id: 47beb3a5-07b5-11eb-9b87-b108ec578218
  last_name: Kurtic
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. EvoPress: Accurate dynamic
    model compression via evolutionary search. In: <i>42nd International Conference
    on Machine Learning</i>. Vol 267. ML Research Press; 2025:55556-55590.'
  apa: 'Sieberling, O., Kuznedelev, D., Kurtic, E., &#38; Alistarh, D.-A. (2025).
    EvoPress: Accurate dynamic model compression via evolutionary search. In <i>42nd
    International Conference on Machine Learning</i> (Vol. 267, pp. 55556–55590).
    Vancouver, Canada: ML Research Press.'
  chicago: 'Sieberling, Oliver, Denis Kuznedelev, Eldar Kurtic, and Dan-Adrian Alistarh.
    “EvoPress: Accurate Dynamic Model Compression via Evolutionary Search.” In <i>42nd
    International Conference on Machine Learning</i>, 267:55556–90. ML Research Press,
    2025.'
  ieee: 'O. Sieberling, D. Kuznedelev, E. Kurtic, and D.-A. Alistarh, “EvoPress: Accurate
    dynamic model compression via evolutionary search,” in <i>42nd International Conference
    on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 55556–55590.'
  ista: 'Sieberling O, Kuznedelev D, Kurtic E, Alistarh D-A. 2025. EvoPress: Accurate
    dynamic model compression via evolutionary search. 42nd International Conference
    on Machine Learning. ICML: International Conference on Machine Learning, PMLR,
    vol. 267, 55556–55590.'
  mla: 'Sieberling, Oliver, et al. “EvoPress: Accurate Dynamic Model Compression via
    Evolutionary Search.” <i>42nd International Conference on Machine Learning</i>,
    vol. 267, ML Research Press, 2025, pp. 55556–90.'
  short: O. Sieberling, D. Kuznedelev, E. Kurtic, D.-A. Alistarh, in:, 42nd International
    Conference on Machine Learning, ML Research Press, 2025, pp. 55556–55590.
conference:
  end_date: 2025-07-19
  location: Vancouver, Canada
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2025-07-13
corr_author: '1'
date_created: 2025-12-14T23:02:05Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-12-16T12:34:32Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2410.14649'
file:
- access_level: open_access
  checksum: 1d744fbaeb199b08e8b6f48bc0dd047e
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-16T12:32:40Z
  date_updated: 2025-12-16T12:32:40Z
  file_id: '20828'
  file_name: 2025_ICML_Sieberling.pdf
  file_size: 908379
  relation: main_file
  success: 1
file_date_updated: 2025-12-16T12:32:40Z
has_accepted_license: '1'
intvolume: '       267'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 55556-55590
publication: 42nd International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'EvoPress: Accurate dynamic model compression via evolutionary search'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '20821'
abstract:
- lang: eng
  text: Modern deep neural networks exhibit heterogeneity across numerous layers of
    various types such as residuals, multi-head attention, etc., due to varying structures
    (dimensions, activation functions, etc.), distinct representation characteristics,
    which impact predictions. We develop a general layer-wise quantization framework
    with tight variance and code-length bounds, adapting to the heterogeneities over
    the course of training. We then apply a new layer-wise quantization technique
    within distributed variational inequalities (VIs), proposing a novel Quantized
    Optimistic Dual Averaging (QODA) algorithm with adaptive learning rates, which
    achieves competitive convergence rates for monotone VIs. We empirically show that
    QODA achieves up to a 150% speedup over the baselines in end-to-end training time
    for training Wasserstein GAN on 12+GPUs.
acknowledgement: "This work was supported by Hasler Foundation Program: Hasler Responsible
  AI (project number 21043). The research was also sponsored by the Army Research
  Office and was accomplished under Grant Number W911NF-24-1-0048. This work was further
  funded by the Swiss National Science Foundation (SNSF) under grant number 200021_205011.
  We also acknowledge project A11 of the Swiss National Supercomputing Centre (CSCS)
  for providing computing resources. Dan Alistarh and Ilia Markov were supported in
  part through the ERC Proofof-Concept grant FastML (Grant Agreement 101158077). Ali
  Ramezani-Kebrya was supported by the Research Council of Norway through FRIPRO Grant
  under project number 356103, its Centres of Excellence scheme, Integreat - Norwegian
  Centre for knowledge-driven machine learning under\r\nproject number 332645 - and
  its Centre for Research-based Innovation funding scheme (Visual Intelligence under
  grant no. 309439)."
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Anh Duc
  full_name: Nguyen, Anh Duc
  last_name: Nguyen
- first_name: Ilia
  full_name: Markov, Ilia
  id: D0CF4148-C985-11E9-8066-0BDEE5697425
  last_name: Markov
- first_name: Frank Zhengqing
  full_name: Wu, Frank Zhengqing
  last_name: Wu
- first_name: Ali
  full_name: Ramezani-Kebrya, Ali
  last_name: Ramezani-Kebrya
- first_name: Kimon
  full_name: Antonakopoulos, Kimon
  last_name: Antonakopoulos
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Volkan
  full_name: Cevher, Volkan
  last_name: Cevher
citation:
  ama: 'Nguyen AD, Markov I, Wu FZ, et al. Layer-wise quantization for quantized optimistic
    dual averaging. In: <i>42nd International Conference on Machine Learning</i>.
    Vol 267. ML Research Press; 2025:46026-46072.'
  apa: 'Nguyen, A. D., Markov, I., Wu, F. Z., Ramezani-Kebrya, A., Antonakopoulos,
    K., Alistarh, D.-A., &#38; Cevher, V. (2025). Layer-wise quantization for quantized
    optimistic dual averaging. In <i>42nd International Conference on Machine Learning</i>
    (Vol. 267, pp. 46026–46072). Vancouver, Canada: ML Research Press.'
  chicago: Nguyen, Anh Duc, Ilia Markov, Frank Zhengqing Wu, Ali Ramezani-Kebrya,
    Kimon Antonakopoulos, Dan-Adrian Alistarh, and Volkan Cevher. “Layer-Wise Quantization
    for Quantized Optimistic Dual Averaging.” In <i>42nd International Conference
    on Machine Learning</i>, 267:46026–72. ML Research Press, 2025.
  ieee: A. D. Nguyen <i>et al.</i>, “Layer-wise quantization for quantized optimistic
    dual averaging,” in <i>42nd International Conference on Machine Learning</i>,
    Vancouver, Canada, 2025, vol. 267, pp. 46026–46072.
  ista: 'Nguyen AD, Markov I, Wu FZ, Ramezani-Kebrya A, Antonakopoulos K, Alistarh
    D-A, Cevher V. 2025. Layer-wise quantization for quantized optimistic dual averaging.
    42nd International Conference on Machine Learning. ICML: International Conference
    on Machine Learning, PMLR, vol. 267, 46026–46072.'
  mla: Nguyen, Anh Duc, et al. “Layer-Wise Quantization for Quantized Optimistic Dual
    Averaging.” <i>42nd International Conference on Machine Learning</i>, vol. 267,
    ML Research Press, 2025, pp. 46026–72.
  short: A.D. Nguyen, I. Markov, F.Z. Wu, A. Ramezani-Kebrya, K. Antonakopoulos, D.-A.
    Alistarh, V. Cevher, in:, 42nd International Conference on Machine Learning, ML
    Research Press, 2025, pp. 46026–46072.
conference:
  end_date: 2025-07-19
  location: Vancouver, Canada
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2025-07-13
date_created: 2025-12-14T23:02:06Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-12-16T12:46:54Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2505.14371'
file:
- access_level: open_access
  checksum: a7edf0e4304171a3e035842b3aab1704
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-16T12:45:41Z
  date_updated: 2025-12-16T12:45:41Z
  file_id: '20830'
  file_name: 2025_ICML_Nguyen.pdf
  file_size: 756213
  relation: main_file
  success: 1
file_date_updated: 2025-12-16T12:45:41Z
has_accepted_license: '1'
intvolume: '       267'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 46026-46072
project:
- _id: 8e35c14b-16d5-11f0-9cad-a3fc35339161
  grant_number: '101158077'
  name: 'FastML: Efficient and Cost-Effective Distributed Machine Learning'
publication: 42nd International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Layer-wise quantization for quantized optimistic dual averaging
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20844'
abstract:
- lang: eng
  text: "We introduce and construct a new proof system called Non-interactive Arguments
    of Knowledge or Space (NArKoS), where a space-bounded prover can convince a verifier
    they know a secret, while having access to sufficient space allows one to forge
    indistinguishable proofs without the secret.\r\nAn application of NArKoS are space-deniable
    proofs, which are proofs of knowledge (say for authentication in access control)
    that are sound when executed by a lightweight device like a smart-card or an RFID
    chip that cannot have much storage, but are deniable (in the strong sense of online
    deniability) as the verifier, like a card reader, can efficiently forge such proofs.\r\nWe
    construct NArKoS in the random oracle model using an OR-proof combining a sigma
    protocol (for the proof of knowledge of the secret) with a new proof system called
    simulatable Proof of Transient Space (simPoTS). We give two different constructions
    of simPoTS, one based on labelling graphs with high pebbling complexity, a technique
    used in the construction of memory-hard functions and proofs of space, and a more
    practical construction based on the verifiable space-hard functions from TCC’24
    where a prover must compute a root of a sparse polynomial. In both cases, the
    main challenge is making the proofs efficiently simulatable."
acknowledgement: "Jesko Dujmovic: Funded by the European Union (ERC, LACONIC, 101041207).
  Views and opinions expressed are however those of the author(s) only and do not
  necessarily reflect those of the European Union or the European Research Council.
  Neither the European Union nor the granting authority can be held responsible for
  them.\r\nChristoph U. Günther and Krzysztof Pietrzak: This research was funded in
  whole or in part by the Austrian Science Fund (FWF) 10.55776/F85. For open access
  purposes, the author has applied a CC BY public copyright license to any author-accepted
  manuscript version arising from this submission."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Jesko
  full_name: Dujmovic, Jesko
  last_name: Dujmovic
- first_name: Christoph Ullrich
  full_name: Günther, Christoph Ullrich
  id: ec98511c-eb8e-11eb-b029-edd25d7271a1
  last_name: Günther
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Dujmovic J, Günther CU, Pietrzak KZ. Space-deniable proofs. In: <i>23rd International
    Conference on Theory of Cryptography</i>. Vol 16271. Springer Nature; 2025:171-202.
    doi:<a href="https://doi.org/10.1007/978-3-032-12290-2_6">10.1007/978-3-032-12290-2_6</a>'
  apa: 'Dujmovic, J., Günther, C. U., &#38; Pietrzak, K. Z. (2025). Space-deniable
    proofs. In <i>23rd International Conference on Theory of Cryptography</i> (Vol.
    16271, pp. 171–202). Aarhus, Denmark: Springer Nature. <a href="https://doi.org/10.1007/978-3-032-12290-2_6">https://doi.org/10.1007/978-3-032-12290-2_6</a>'
  chicago: Dujmovic, Jesko, Christoph Ullrich Günther, and Krzysztof Z Pietrzak. “Space-Deniable
    Proofs.” In <i>23rd International Conference on Theory of Cryptography</i>, 16271:171–202.
    Springer Nature, 2025. <a href="https://doi.org/10.1007/978-3-032-12290-2_6">https://doi.org/10.1007/978-3-032-12290-2_6</a>.
  ieee: J. Dujmovic, C. U. Günther, and K. Z. Pietrzak, “Space-deniable proofs,” in
    <i>23rd International Conference on Theory of Cryptography</i>, Aarhus, Denmark,
    2025, vol. 16271, pp. 171–202.
  ista: 'Dujmovic J, Günther CU, Pietrzak KZ. 2025. Space-deniable proofs. 23rd International
    Conference on Theory of Cryptography. TCC: Theory of Cryptography, LNCS, vol.
    16271, 171–202.'
  mla: Dujmovic, Jesko, et al. “Space-Deniable Proofs.” <i>23rd International Conference
    on Theory of Cryptography</i>, vol. 16271, Springer Nature, 2025, pp. 171–202,
    doi:<a href="https://doi.org/10.1007/978-3-032-12290-2_6">10.1007/978-3-032-12290-2_6</a>.
  short: J. Dujmovic, C.U. Günther, K.Z. Pietrzak, in:, 23rd International Conference
    on Theory of Cryptography, Springer Nature, 2025, pp. 171–202.
conference:
  end_date: 2025-12-05
  location: Aarhus, Denmark
  name: 'TCC: Theory of Cryptography'
  start_date: 2025-12-01
corr_author: '1'
date_created: 2025-12-21T23:01:33Z
date_published: 2025-12-05T00:00:00Z
date_updated: 2025-12-29T11:44:16Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-032-12290-2_6
intvolume: '     16271'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2025/1723
month: '12'
oa: 1
oa_version: Preprint
page: 171-202
project:
- _id: 34a34d57-11ca-11ed-8bc3-a2688a8724e1
  grant_number: F8509
  name: Security and Privacy by Design for Complex Systems
publication: 23rd International Conference on Theory of Cryptography
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783032122896'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Space-deniable proofs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16271
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20847'
abstract:
- lang: eng
  text: "We report on an experimental active matter system with motion restricted
    to four cardinal directions. Our particles are magnetite-doped colloidal spheres
    driven by the Quincke electrorotational instability. The absence of a magnetic
    field (|\U0001D469|=0) leads to circular trajectories interspersed with short
    spontaneous runs. Intermediate fields (|\U0001D469|≲20mT) linearize the motion
    along the axis perpendicular to \U0001D469. At high magnetic fields, we observe
    the surprising emergence of a second, distinct linearization along the axis parallel
    to \U0001D469. With numerical simulations, we show that this behavior can be explained
    by anisotropic magnetic susceptibility."
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: ScienComp
- _id: LifeSc
acknowledgement: "This research was funded in whole or in part by the Austrian Science
  Fund (FWF) [Grant DOI: 10.55776/ESP298]. This project has received funding from
  the European Research Council (ERC) under the European Union’s Horizon 2020 research
  and innovation programme (Grant\r\nAgreement No. 949120). This research was supported
  by the Scientific Service Units of The Institute of Science and Technology Austria
  (ISTA) through resources provided by the Miba Machine Shop, Nanofabrication Facility,
  Scientific Computing Facility, and Lab Support Facility. We wish to acknowledge
  the crucial contributions of Alexandre Morin in getting the project off the ground,
  and Jack Merrin for creating the SU-8 deposition protocol used in the construction
  of our\r\ncells. We also wish to thank Kimberley Modic and Hamza Nasir for their
  work on single-particle characterization. "
article_number: '065418'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Eavan
  full_name: Fitzgerald, Eavan
  id: 2df8ab8f-080d-11ed-979a-bfe651ca3afa
  last_name: Fitzgerald
- first_name: Cécile
  full_name: Clavaud, Cécile
  id: 5f654c5d-04a1-11eb-ab36-ba9ffec58bd8
  last_name: Clavaud
  orcid: 0000-0002-1843-3803
- first_name: Debasish
  full_name: Das, Debasish
  last_name: Das
- first_name: Isaac C
  full_name: Lenton, Isaac C
  id: a550210f-223c-11ec-8182-e2d45e817efb
  last_name: Lenton
  orcid: 0000-0002-5010-6984
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
citation:
  ama: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. Rolling at right
    angles: Magnetic anisotropy enables dual-anisotropic active matter. <i>Physical
    Review E</i>. 2025;112(6). doi:<a href="https://doi.org/10.1103/1ss8-31rb">10.1103/1ss8-31rb</a>'
  apa: 'Fitzgerald, E., Clavaud, C., Das, D., Lenton, I. C., &#38; Waitukaitis, S.
    R. (2025). Rolling at right angles: Magnetic anisotropy enables dual-anisotropic
    active matter. <i>Physical Review E</i>. American Physical Society. <a href="https://doi.org/10.1103/1ss8-31rb">https://doi.org/10.1103/1ss8-31rb</a>'
  chicago: 'Fitzgerald, Eavan, Cécile Clavaud, Debasish Das, Isaac C Lenton, and Scott
    R Waitukaitis. “Rolling at Right Angles: Magnetic Anisotropy Enables Dual-Anisotropic
    Active Matter.” <i>Physical Review E</i>. American Physical Society, 2025. <a
    href="https://doi.org/10.1103/1ss8-31rb">https://doi.org/10.1103/1ss8-31rb</a>.'
  ieee: 'E. Fitzgerald, C. Clavaud, D. Das, I. C. Lenton, and S. R. Waitukaitis, “Rolling
    at right angles: Magnetic anisotropy enables dual-anisotropic active matter,”
    <i>Physical Review E</i>, vol. 112, no. 6. American Physical Society, 2025.'
  ista: 'Fitzgerald E, Clavaud C, Das D, Lenton IC, Waitukaitis SR. 2025. Rolling
    at right angles: Magnetic anisotropy enables dual-anisotropic active matter. Physical
    Review E. 112(6), 065418.'
  mla: 'Fitzgerald, Eavan, et al. “Rolling at Right Angles: Magnetic Anisotropy Enables
    Dual-Anisotropic Active Matter.” <i>Physical Review E</i>, vol. 112, no. 6, 065418,
    American Physical Society, 2025, doi:<a href="https://doi.org/10.1103/1ss8-31rb">10.1103/1ss8-31rb</a>.'
  short: E. Fitzgerald, C. Clavaud, D. Das, I.C. Lenton, S.R. Waitukaitis, Physical
    Review E 112 (2025).
corr_author: '1'
date_created: 2025-12-21T23:01:34Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2025-12-29T11:19:34Z
day: '01'
ddc:
- '530'
department:
- _id: ScWa
doi: 10.1103/1ss8-31rb
ec_funded: 1
external_id:
  arxiv:
  - '2508.05643'
file:
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  checksum: d593e933f976c3f3cde37ad66539d57d
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-29T11:15:42Z
  date_updated: 2025-12-29T11:15:42Z
  file_id: '20862'
  file_name: 2025_PhysReviewE_Fitzgerald.pdf
  file_size: 2131491
  relation: main_file
  success: 1
file_date_updated: 2025-12-29T11:15:42Z
has_accepted_license: '1'
intvolume: '       112'
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: bd8eede5-d553-11ed-ba76-eaded0d13485
  grant_number: E 298
  name: 'MixQUIckR: Mixing with QUIncke Rollers'
- _id: 0aa60e99-070f-11eb-9043-a6de6bdc3afa
  call_identifier: H2020
  grant_number: '949120'
  name: 'Tribocharge: a multi-scale approach to an enduring problem in physics'
publication: Physical Review E
publication_identifier:
  eissn:
  - 2470-0053
  issn:
  - 2470-0045
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Rolling at right angles: Magnetic anisotropy enables dual-anisotropic active
  matter'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20851'
abstract:
- lang: eng
  text: High-voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material
    for high power density in lithium-ion batteries. However, it suffers from poor
    cycle life associated with the rock-salt phase transformation. This study presents
    a straightforward synthesis approach to enhance the electrochemical performance
    of LiNi0.5Mn1.5O4 through a synergistic solid-state modification with LiF and
    AlF3. This dual modification promotes rapid Li⁺ diffusion, enables near-complete
    delithiation/lithiation, approaching the theoretical capacity of disordered LiNi0.5Mn1.5O4,
    and, more importantly, effectively mitigates the formation of the rock-salt phase,
    thereby enhancing structural stability, as confirmed by operando X-ray absorption
    spectroscopy (XAS) and synchrotron X-ray diffraction (SXRD). As a result, the
    optimized LiNi0.5Mn1.5O4 (10 mg AlF3 + 30 mg LiF) delivers high reversible capacities
    of 142.1, 139.1, 129.2, 121.6, 110.3, 93.5, and 76.1 mAh∙g−1 at 0.2C, 0.5C, 1.0C,
    2.0C, 3.0C, 4.0C, and 5.0C, respectively. Full cells using graphite as the anode
    and a high-loading cathode exhibit excellent cycling performance. They retain
    80% of their capacity after 200 cycles at 0.5C within a voltage window of 3.5–4.9
    V with cathode loading of 11 mg∙cm−2. The findings of this study will significantly
    advance high-power LiNi0.5Mn1.5O4 materials, offering improved battery life and
    thereby enhancing their potential for practical applications.
acknowledged_ssus:
- _id: EM-Fac
- _id: NanoFab
acknowledgement: 'This work was supported by the European Commission-financed project
  IntelLigent (HORIZON-CL5-2021-D2-01-02) with project ID number 101069765. In collaboration
  with ALBA staff, the operando SXRD and XAS experiments were performed at BL-16-NOTOS
  beamline at ALBA Synchrotron Light Source (experiment number: 2023097765). This
  research was supported by the Scientific Service Units (SSU) of the Institute of
  Science and Technology Austria (ISTA) through resources provided by the Electron
  Microscopy Facility (EMF) and the Nanofabrication Facility (NFF), and M.I. and S.H.
  acknowledge financial support from ISTA and the Werner Siemens Foundation. Jordi
  Jacas Biendicho acknowledges the fellowship RYC2021-034994-I, funded by MICIU/AEI/10.13039/501100011033
  and the European Union «NextGenerationEU»/PRTR». Jordi Llorca is a Serra Húnter
  Fellow and is grateful to projects MICIN/AEI/FEDER PID2021-124572OB-C31 and Maria
  de Maeztu Units of Excellence Programme CEX2023-001300-M, and GC 2021 SGR 01061.'
article_number: e15962
article_processing_charge: Yes
article_type: original
author:
- first_name: Xingqi
  full_name: Chang, Xingqi
  last_name: Chang
- first_name: Carlos
  full_name: Escudero, Carlos
  last_name: Escudero
- first_name: Ashley P.
  full_name: Black, Ashley P.
  last_name: Black
- first_name: Sharona
  full_name: Horta, Sharona
  id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc
  last_name: Horta
- first_name: Elías
  full_name: Martínez, Elías
  last_name: Martínez
- first_name: Xuan
  full_name: Lu, Xuan
  last_name: Lu
- first_name: Jordi
  full_name: Llorca, Jordi
  last_name: Llorca
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Jordi Jacas
  full_name: Biendicho, Jordi Jacas
  last_name: Biendicho
- first_name: Andreu
  full_name: Cabot, Andreu
  last_name: Cabot
citation:
  ama: Chang X, Escudero C, Black AP, et al. Mitigating the rock-salt phase transformation
    in disordered LNMO through synergetic solid-state AlF3/LiF modifications. <i>Advanced
    Science</i>. 2025. doi:<a href="https://doi.org/10.1002/advs.202515962">10.1002/advs.202515962</a>
  apa: Chang, X., Escudero, C., Black, A. P., Horta, S., Martínez, E., Lu, X., … Cabot,
    A. (2025). Mitigating the rock-salt phase transformation in disordered LNMO through
    synergetic solid-state AlF3/LiF modifications. <i>Advanced Science</i>. Wiley.
    <a href="https://doi.org/10.1002/advs.202515962">https://doi.org/10.1002/advs.202515962</a>
  chicago: Chang, Xingqi, Carlos Escudero, Ashley P. Black, Sharona Horta, Elías Martínez,
    Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, and Andreu Cabot.
    “Mitigating the Rock-Salt Phase Transformation in Disordered LNMO through Synergetic
    Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>. Wiley, 2025. <a
    href="https://doi.org/10.1002/advs.202515962">https://doi.org/10.1002/advs.202515962</a>.
  ieee: X. Chang <i>et al.</i>, “Mitigating the rock-salt phase transformation in
    disordered LNMO through synergetic solid-state AlF3/LiF modifications,” <i>Advanced
    Science</i>. Wiley, 2025.
  ista: Chang X, Escudero C, Black AP, Horta S, Martínez E, Lu X, Llorca J, Ibáñez
    M, Biendicho JJ, Cabot A. 2025. Mitigating the rock-salt phase transformation
    in disordered LNMO through synergetic solid-state AlF3/LiF modifications. Advanced
    Science., e15962.
  mla: Chang, Xingqi, et al. “Mitigating the Rock-Salt Phase Transformation in Disordered
    LNMO through Synergetic Solid-State AlF3/LiF Modifications.” <i>Advanced Science</i>,
    e15962, Wiley, 2025, doi:<a href="https://doi.org/10.1002/advs.202515962">10.1002/advs.202515962</a>.
  short: X. Chang, C. Escudero, A.P. Black, S. Horta, E. Martínez, X. Lu, J. Llorca,
    M. Ibáñez, J.J. Biendicho, A. Cabot, Advanced Science (2025).
date_created: 2025-12-21T23:01:35Z
date_published: 2025-12-12T00:00:00Z
date_updated: 2025-12-29T10:15:43Z
day: '12'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1002/advs.202515962
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa_version: Published Version
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: Advanced Science
publication_identifier:
  eissn:
  - 2198-3844
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mitigating the rock-salt phase transformation in disordered LNMO through synergetic
  solid-state AlF3/LiF modifications
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20857'
abstract:
- lang: eng
  text: 'Evolutionary games provide a flexible mathematical framework for many problems
    in biology and social evolution. Prisoners’ dilemma, and in particular, the important
    special case of donation games, represents social dilemmas where cooperation is
    mutually beneficial, yet defection is preferred by selfish agents. In evolutionary
    games on networks, the agents interact over a population structure. The existence
    of population structures that promote cooperative behavior is a fascinating and
    active research topic. Previous research establishes structures promoting cooperation
    in the limit of weak selection where the benefit-to-cost ratio β exceeds 1.5.
    The existence of such structures for medium and strong selection for 1 < ß < 2
    and for weak selection for 1 < ß < 1.5 has been a long-standing open question.
    First, we answer the open questions in the affirmative: For every selection strength
    and every ß > 1, we construct networks promoting cooperation. Second, we present
    a robustness result with respect to β and selection strength: Our structures promote
    cooperation for a range of these parameter values rather than specific parameter
    values. Finally, we supplement our theoretical results with simulation results
    on small population structures that show the effectiveness of our construction
    over well-studied population structures.'
acknowledgement: J.S. and K.C. were supported by the European Research Council CoG
  863818 (ForM-SMArt) and Austrian Science Fund (FWF) 10.55776/COE12.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jakub
  full_name: Svoboda, Jakub
  id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
  last_name: Svoboda
  orcid: 0000-0002-1419-3267
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
citation:
  ama: Svoboda J, Chatterjee K. Promoters of cooperation in evolutionary games. <i>Proceedings
    of the National Academy of Sciences</i>. 2025;122(51):e2524109122. doi:<a href="https://doi.org/10.1073/pnas.2524109122">10.1073/pnas.2524109122</a>
  apa: Svoboda, J., &#38; Chatterjee, K. (2025). Promoters of cooperation in evolutionary
    games. <i>Proceedings of the National Academy of Sciences</i>. National Academy
    of Sciences. <a href="https://doi.org/10.1073/pnas.2524109122">https://doi.org/10.1073/pnas.2524109122</a>
  chicago: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in
    Evolutionary Games.” <i>Proceedings of the National Academy of Sciences</i>. National
    Academy of Sciences, 2025. <a href="https://doi.org/10.1073/pnas.2524109122">https://doi.org/10.1073/pnas.2524109122</a>.
  ieee: J. Svoboda and K. Chatterjee, “Promoters of cooperation in evolutionary games,”
    <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 51. National
    Academy of Sciences, p. e2524109122, 2025.
  ista: Svoboda J, Chatterjee K. 2025. Promoters of cooperation in evolutionary games.
    Proceedings of the National Academy of Sciences. 122(51), e2524109122.
  mla: Svoboda, Jakub, and Krishnendu Chatterjee. “Promoters of Cooperation in Evolutionary
    Games.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no.
    51, National Academy of Sciences, 2025, p. e2524109122, doi:<a href="https://doi.org/10.1073/pnas.2524109122">10.1073/pnas.2524109122</a>.
  short: J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences
    122 (2025) e2524109122.
corr_author: '1'
date_created: 2025-12-28T23:01:26Z
date_published: 2025-12-15T00:00:00Z
date_updated: 2026-02-16T12:34:04Z
day: '15'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1073/pnas.2524109122
ec_funded: 1
external_id:
  pmid:
  - '41397136'
file:
- access_level: open_access
  checksum: dd50b62a1efc28c0133fe9c11dbee53c
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-29T09:36:50Z
  date_updated: 2025-12-29T09:36:50Z
  file_id: '20860'
  file_name: 2025_PNAS_Svoboda.pdf
  file_size: 2308124
  relation: main_file
  success: 1
file_date_updated: 2025-12-29T09:36:50Z
has_accepted_license: '1'
intvolume: '       122'
issue: '51'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: e2524109122
pmid: 1
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  eissn:
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Promoters of cooperation in evolutionary games
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 122
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20858'
abstract:
- lang: eng
  text: Targeted antigen delivery to immune cells, particularly dendritic cells, has
    emerged as a promising strategy to enhance therapeutic efficacy of vaccines, while
    minimizing adverse effects associated with conventional immunization. In this
    study, we use our previously described small glycomimetic molecule that is selectively
    recognized by the Langerhans cell (LC)-specific surface receptor Langerin and
    demonstrate specific delivery of protein antigens to these specialized dendritic
    cells. Our results show that Langerin-mediated antigen delivery significantly
    enhances the immune response in vivo, resulting in increased expansion and activation
    of antigen-specific T cells, compared to immunization with unmodified antigen.
    We demonstrate the feasibility of our LC-targeted platform for immune cell-specific
    immunization with protein antigen and underscore the potential of LCs as an access
    point for next-generation vaccines and immunotherapies.
acknowledgement: This project was generously supported by Seedfinancing (grant no.
  P2282679) of the Austrian Bundesministerium für Digitalisierung und Wirtschaftsstandort
  and the Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation,
  und Technologie, handled by the Austrian Wirtschaftsservice (aws), as well as by
  Life Science Call 2022 (grant no. FO999896442) of the Austrian Research Promotion
  Agency (FFG). We thank Mag. Michael Schunn from the PCF of the Institute of Science
  and Technology Austria for his continuous technical support.
article_processing_charge: No
article_type: original
author:
- first_name: Ramona
  full_name: Rica, Ramona
  last_name: Rica
- first_name: Klara
  full_name: Klein, Klara
  last_name: Klein
- first_name: Litty
  full_name: Johnson, Litty
  last_name: Johnson
- first_name: Gabriele
  full_name: Carta, Gabriele
  last_name: Carta
- first_name: Mirza
  full_name: Sarcevic, Mirza
  last_name: Sarcevic
- first_name: Freyja
  full_name: Langer, Freyja
  id: 3C1BE782-F248-11E8-B48F-1D18A9856A87
  last_name: Langer
- first_name: Christoph
  full_name: Rademacher, Christoph
  last_name: Rademacher
- first_name: Robert
  full_name: Wawrzinek, Robert
  last_name: Wawrzinek
- first_name: Federica
  full_name: Quattrone, Federica
  last_name: Quattrone
- first_name: Florian
  full_name: Sparber, Florian
  last_name: Sparber
citation:
  ama: Rica R, Klein K, Johnson L, et al. Langerhans cell-targeted protein delivery
    enhances antigen-specific cellular immune response. <i>Molecular Therapy</i>.
    doi:<a href="https://doi.org/10.1016/j.ymthe.2025.10.008">10.1016/j.ymthe.2025.10.008</a>
  apa: Rica, R., Klein, K., Johnson, L., Carta, G., Sarcevic, M., Langer, F., … Sparber,
    F. (n.d.). Langerhans cell-targeted protein delivery enhances antigen-specific
    cellular immune response. <i>Molecular Therapy</i>. Elsevier. <a href="https://doi.org/10.1016/j.ymthe.2025.10.008">https://doi.org/10.1016/j.ymthe.2025.10.008</a>
  chicago: Rica, Ramona, Klara Klein, Litty Johnson, Gabriele Carta, Mirza Sarcevic,
    Freyja Langer, Christoph Rademacher, Robert Wawrzinek, Federica Quattrone, and
    Florian Sparber. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific
    Cellular Immune Response.” <i>Molecular Therapy</i>. Elsevier, n.d. <a href="https://doi.org/10.1016/j.ymthe.2025.10.008">https://doi.org/10.1016/j.ymthe.2025.10.008</a>.
  ieee: R. Rica <i>et al.</i>, “Langerhans cell-targeted protein delivery enhances
    antigen-specific cellular immune response,” <i>Molecular Therapy</i>. Elsevier.
  ista: Rica R, Klein K, Johnson L, Carta G, Sarcevic M, Langer F, Rademacher C, Wawrzinek
    R, Quattrone F, Sparber F. Langerhans cell-targeted protein delivery enhances
    antigen-specific cellular immune response. Molecular Therapy.
  mla: Rica, Ramona, et al. “Langerhans Cell-Targeted Protein Delivery Enhances Antigen-Specific
    Cellular Immune Response.” <i>Molecular Therapy</i>, Elsevier, doi:<a href="https://doi.org/10.1016/j.ymthe.2025.10.008">10.1016/j.ymthe.2025.10.008</a>.
  short: R. Rica, K. Klein, L. Johnson, G. Carta, M. Sarcevic, F. Langer, C. Rademacher,
    R. Wawrzinek, F. Quattrone, F. Sparber, Molecular Therapy (n.d.).
date_created: 2025-12-28T23:01:26Z
date_published: 2025-10-04T00:00:00Z
date_updated: 2025-12-29T09:55:05Z
day: '04'
department:
- _id: PreCl
doi: 10.1016/j.ymthe.2025.10.008
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2025.05.05.652195
month: '10'
oa: 1
oa_version: Preprint
publication: Molecular Therapy
publication_identifier:
  eissn:
  - 1525-0024
  issn:
  - 1525-0016
publication_status: inpress
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Langerhans cell-targeted protein delivery enhances antigen-specific cellular
  immune response
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20859'
abstract:
- lang: eng
  text: Effective immune responses rely on the efficient migration of leukocytes.
    Yet, how temperature regulates migration dynamics at the single-cell level has
    remained poorly understood. Using zebrafish embryos and mouse tissue explants,
    we found that temperature positively regulates leukocyte migration speed, exploration,
    and arrival frequencies to wounds and lymph vessels. Complementary 2D and 3D cultures
    revealed that this thermokinetic control of cell migration is conserved across
    immune cell types, independently of the 3D tissue environment. By applying precise
    (sub-)cellular temperature modulation, we identified a rapid and reversible thermo-response
    that depends on myosin II activity. Small physiological increases in temperature
    (1°C –2°C), as present during fever-like conditions, profoundly increased immune
    responses by accelerating arrival times at lymphatic vessels and tissue wounds.
    These findings identify myosin-II-dependent actomyosin contractility as a critical
    mechanical structure regulating single-cell thermo-adaptability, with physiological
    implications for tuning the speed of immune responses in vivo.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: 'The authors would like to acknowledge the Super Resolution Light
  Microcopy and Nanoscopy (SLN) Facility of ICFO for their support with imaging experiments,
  Johann Osmond (Nanofabrication laboratory, ICFO) for the design and production of
  molds for generating confinement coverslip, Merche Rivas for cell culture of immune
  cells and further support from the CRG Core Facilities for Genomics and Advanced
  Light Microscopy. We would like to thank Michael Sixt for discussions on this work
  and the Quidant, Ruprecht, and Wieser lab members for critical reading of the manuscript.
  This research was supported by the Scientific Service Units (SSU) of IST-Austria
  through resources provided by the Nanofabrication Facility (NFF). C.A. acknowledges
  the funding from the European Union’s Horizon 2020 research and innovation programme
  under the Marie Skłodowska-Curie grant agreement no 847517 and V.V. from the ICFOstepstone
  – PhD Programme funded by the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement no 665884. S.W. acknowledges
  support through the Spanish Ministry of Economy and Competitiveness via MINECO’s
  Plan Nacional (BFU2017-86296-P). V.R. acknowledges funding from the European Union’s
  HORIZON-EIC-2021-PATHFINDEROPEN program under grant agreement no. 101046620 and
  European Union''s Horizon Europe program under the grant agreement no. 101072123.
  E.K. acknowledges funding by a fellowship of the Ministry of Innovation, Science
  and Research of North-Rhine-Westphalia (AZ: 421-8.03.03.02-137069) and the Deutsche
  Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence
  Strategy – EXC 2151 – 390873048 and by the TRA Life and Health (University of Bonn)
  as part of the Excellence Strategy of the federal and state governments.'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Iván
  full_name: Company-Garrido, Iván
  last_name: Company-Garrido
- first_name: Alberto
  full_name: Zurita Carpio, Alberto
  last_name: Zurita Carpio
- first_name: Mariona
  full_name: Colomer-Rosell, Mariona
  last_name: Colomer-Rosell
- first_name: Bernard
  full_name: Ciraulo, Bernard
  last_name: Ciraulo
- first_name: Ronja
  full_name: Molkenbur, Ronja
  last_name: Molkenbur
- first_name: Peter
  full_name: Lanzerstorfer, Peter
  last_name: Lanzerstorfer
- first_name: Fabio
  full_name: Pezzano, Fabio
  last_name: Pezzano
- first_name: Costanza
  full_name: Agazzi, Costanza
  last_name: Agazzi
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Saumey
  full_name: Jain, Saumey
  last_name: Jain
- first_name: Jeroen M.
  full_name: Jacques, Jeroen M.
  last_name: Jacques
- first_name: Valeria
  full_name: Venturini, Valeria
  last_name: Venturini
- first_name: Christian
  full_name: Knapp, Christian
  last_name: Knapp
- first_name: Yufei
  full_name: Xie, Yufei
  last_name: Xie
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Julian
  full_name: Weghuber, Julian
  last_name: Weghuber
- first_name: Marcel
  full_name: Schaaf, Marcel
  last_name: Schaaf
- first_name: Romain
  full_name: Quidant, Romain
  last_name: Quidant
- first_name: Eva
  full_name: Kiermaier, Eva
  id: 3EB04B78-F248-11E8-B48F-1D18A9856A87
  last_name: Kiermaier
  orcid: 0000-0001-6165-5738
- first_name: Jaime
  full_name: Ortega Arroyo, Jaime
  last_name: Ortega Arroyo
- first_name: Verena
  full_name: Ruprecht, Verena
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Stefan
  full_name: Wieser, Stefan
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
citation:
  ama: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, et al. Myosin II regulates
    cellular thermo-adaptability and the efficiency of immune responses. <i>Developmental
    Cell</i>. 2025. doi:<a href="https://doi.org/10.1016/j.devcel.2025.10.006">10.1016/j.devcel.2025.10.006</a>
  apa: Company-Garrido, I., Zurita Carpio, A., Colomer-Rosell, M., Ciraulo, B., Molkenbur,
    R., Lanzerstorfer, P., … Wieser, S. (2025). Myosin II regulates cellular thermo-adaptability
    and the efficiency of immune responses. <i>Developmental Cell</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.devcel.2025.10.006">https://doi.org/10.1016/j.devcel.2025.10.006</a>
  chicago: Company-Garrido, Iván, Alberto Zurita Carpio, Mariona Colomer-Rosell, Bernard
    Ciraulo, Ronja Molkenbur, Peter Lanzerstorfer, Fabio Pezzano, et al. “Myosin II
    Regulates Cellular Thermo-Adaptability and the Efficiency of Immune Responses.”
    <i>Developmental Cell</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.devcel.2025.10.006">https://doi.org/10.1016/j.devcel.2025.10.006</a>.
  ieee: I. Company-Garrido <i>et al.</i>, “Myosin II regulates cellular thermo-adaptability
    and the efficiency of immune responses,” <i>Developmental Cell</i>. Elsevier,
    2025.
  ista: Company-Garrido I, Zurita Carpio A, Colomer-Rosell M, Ciraulo B, Molkenbur
    R, Lanzerstorfer P, Pezzano F, Agazzi C, Hauschild R, Jain S, Jacques JM, Venturini
    V, Knapp C, Xie Y, Merrin J, Weghuber J, Schaaf M, Quidant R, Kiermaier E, Ortega
    Arroyo J, Ruprecht V, Wieser S. 2025. Myosin II regulates cellular thermo-adaptability
    and the efficiency of immune responses. Developmental Cell.
  mla: Company-Garrido, Iván, et al. “Myosin II Regulates Cellular Thermo-Adaptability
    and the Efficiency of Immune Responses.” <i>Developmental Cell</i>, Elsevier,
    2025, doi:<a href="https://doi.org/10.1016/j.devcel.2025.10.006">10.1016/j.devcel.2025.10.006</a>.
  short: I. Company-Garrido, A. Zurita Carpio, M. Colomer-Rosell, B. Ciraulo, R. Molkenbur,
    P. Lanzerstorfer, F. Pezzano, C. Agazzi, R. Hauschild, S. Jain, J.M. Jacques,
    V. Venturini, C. Knapp, Y. Xie, J. Merrin, J. Weghuber, M. Schaaf, R. Quidant,
    E. Kiermaier, J. Ortega Arroyo, V. Ruprecht, S. Wieser, Developmental Cell (2025).
date_created: 2025-12-28T23:01:27Z
date_published: 2025-11-04T00:00:00Z
date_updated: 2025-12-29T09:23:58Z
day: '04'
ddc:
- '570'
department:
- _id: Bio
- _id: NanoFab
doi: 10.1016/j.devcel.2025.10.006
external_id:
  pmid:
  - '41192429'
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2025.10.006
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Myosin II regulates cellular thermo-adaptability and the efficiency of immune
  responses
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20866'
abstract:
- lang: eng
  text: In this work, we present hypernode automata as a specification formalism for
    hyperproperties of systems whose executions may be misaligned among themselves,
    such as concurrent systems. These automata consist of nodes labeled with hypernode
    logic formulas and transitions marked with synchronizing actions. Hypernode logic
    formulas establish relations between sequences of variable values among different
    system executions. This logic enables both synchronous and asynchronous analysis
    of traces. In its asynchronous view on execution traces, hypernode formulas establish
    relations on the order of value changes for each variable without correlating
    their timing. In both views, the analysis of different execution traces is synchronized
    through the transitions of hypernode automata. By combining logic’s declarative
    nature with automata’s procedural power, hypernode automata seamlessly integrate
    asynchronicity requirements at the node level with synchronicity between node
    transitions. We show that the model-checking problem for hypernode automata is
    decidable for specifications where each node specifies either a synchronous or
    an asynchronous requirement for the system’s executions, but not both.
acknowledgement: This work was supported in part by the Austrian Science Fund (FWF)
  SFB project SpyCoDe 10.55776/F85, by the FWF projects ZK-35 and W1255-N23, and by
  the ERC Advanced Grant VAMOS 101020093. Open access funding provided by Institute
  of Science and Technology (IST Austria).
article_number: '43'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Ezio
  full_name: Bartocci, Ezio
  last_name: Bartocci
- first_name: Marek
  full_name: Chalupa, Marek
  id: 87e34708-d6c6-11ec-9f5b-9391e7be2463
  last_name: Chalupa
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Dejan
  full_name: Nickovic, Dejan
  id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
  last_name: Nickovic
- first_name: Ana
  full_name: Oliveira da Costa, Ana
  id: f347ec37-6676-11ee-b395-a888cb7b4fb4
  last_name: Oliveira da Costa
  orcid: 0000-0002-8741-5799
citation:
  ama: Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode
    automata. <i>Acta Informatica</i>. 2025;62(4). doi:<a href="https://doi.org/10.1007/s00236-025-00509-8">10.1007/s00236-025-00509-8</a>
  apa: Bartocci, E., Chalupa, M., Henzinger, T. A., Nickovic, D., &#38; Oliveira da
    Costa, A. (2025). Hypernode automata. <i>Acta Informatica</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00236-025-00509-8">https://doi.org/10.1007/s00236-025-00509-8</a>
  chicago: Bartocci, Ezio, Marek Chalupa, Thomas A Henzinger, Dejan Nickovic, and
    Ana Oliveira da Costa. “Hypernode Automata.” <i>Acta Informatica</i>. Springer
    Nature, 2025. <a href="https://doi.org/10.1007/s00236-025-00509-8">https://doi.org/10.1007/s00236-025-00509-8</a>.
  ieee: E. Bartocci, M. Chalupa, T. A. Henzinger, D. Nickovic, and A. Oliveira da
    Costa, “Hypernode automata,” <i>Acta Informatica</i>, vol. 62, no. 4. Springer
    Nature, 2025.
  ista: Bartocci E, Chalupa M, Henzinger TA, Nickovic D, Oliveira da Costa A. 2025.
    Hypernode automata. Acta Informatica. 62(4), 43.
  mla: Bartocci, Ezio, et al. “Hypernode Automata.” <i>Acta Informatica</i>, vol.
    62, no. 4, 43, Springer Nature, 2025, doi:<a href="https://doi.org/10.1007/s00236-025-00509-8">10.1007/s00236-025-00509-8</a>.
  short: E. Bartocci, M. Chalupa, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa,
    Acta Informatica 62 (2025).
corr_author: '1'
date_created: 2025-12-29T12:07:12Z
date_published: 2025-12-09T00:00:00Z
date_updated: 2026-01-05T12:27:41Z
day: '09'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/s00236-025-00509-8
ec_funded: 1
external_id:
  arxiv:
  - '2305.02836'
file:
- access_level: open_access
  checksum: 06ed45a1218ad8464818803ae2968aaf
  content_type: application/pdf
  creator: dernst
  date_created: 2026-01-05T12:26:43Z
  date_updated: 2026-01-05T12:26:43Z
  file_id: '20944'
  file_name: 2025_ActaInformatica_Bartocci.pdf
  file_size: 7117003
  relation: main_file
  success: 1
file_date_updated: 2026-01-05T12:26:43Z
has_accepted_license: '1'
intvolume: '        62'
issue: '4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
- _id: 34a1b658-11ca-11ed-8bc3-c75229f0241e
  grant_number: F8502
  name: Interface Theory for Security and Privacy
publication: Acta Informatica
publication_identifier:
  eissn:
  - 1432-0525
  issn:
  - 0001-5903
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '14405'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Hypernode automata
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 62
year: '2025'
...
---
OA_type: closed access
_id: '20868'
abstract:
- lang: eng
  text: Residents of low-latitude megacities face growing vulnerability to humid-heat
    stress under urbanization and global warming, yet limited research has assessed
    the morbidity burden of mental and behavioral disorders (MBDs) linked to humid-heat
    exposures in these cities. Here we quantify the hospital admissions of MBDs in
    Shanghai, a megacity of over 25 million inhabitants, attributable to humid heat,
    and project future burdens under various greenhouse gas (GHG)-emission and population
    scenarios. Humid heat drives a higher morbidity burden than high temperature alone,
    especially in humid-heat nights. Without population change, the humid-heat-related
    morbidity burden of MBDs would increase by 68.2% (95% empirical confidence interval
    56.7%–81.6%) under the highest-GHG-emission scenario by the 2090s, while 8,465
    (95% empirical confidence interval 6,928–10,053) cases would be avoided by reducing
    emissions to the lowest pathway. With projected population decline, the attributable
    hospital admissions will decrease toward century’s end. These findings highlight
    the benefit of GHG mitigation in reducing the growing MBD risks posed by extreme
    humid heat.
acknowledgement: 'This research was supported by the National Natural Science Foundation
  of China (grants 42288101 and 42175066) and Shanghai International Science and Technology
  Partnership Project (grant 21230780200). G.S. is supported by the China Brain Project
  (grant 2025ZD0215100), the National Natural Science Foundation of China (grant 82150710554),
  the Chinese National Key Project (grant 2023YFE0199700), the National Natural Science
  Foundation of China (grant W2541022) and the EC Horizon Europe: environMENTAL project.'
article_processing_charge: No
article_type: original
author:
- first_name: Chen
  full_name: Liang, Chen
  last_name: Liang
- first_name: Jiacan
  full_name: Yuan, Jiacan
  last_name: Yuan
- first_name: Renhe
  full_name: Zhang, Renhe
  last_name: Zhang
- first_name: Xu
  full_name: Tang, Xu
  last_name: Tang
- first_name: Gunter
  full_name: Schumann, Gunter
  last_name: Schumann
- first_name: Esther
  full_name: Hitchen, Esther
  last_name: Hitchen
- first_name: Elli
  full_name: Polemiti, Elli
  last_name: Polemiti
- first_name: Emin
  full_name: Serin, Emin
  last_name: Serin
- first_name: Hedi
  full_name: Kebir, Hedi
  last_name: Kebir
- first_name: Tristram A.
  full_name: Lett, Tristram A.
  last_name: Lett
- first_name: Nilakshi
  full_name: Vaidya, Nilakshi
  last_name: Vaidya
- first_name: Jean-Charles
  full_name: Roy, Jean-Charles
  last_name: Roy
- first_name: Henrik
  full_name: Walter, Henrik
  last_name: Walter
- first_name: Andreas
  full_name: Heinz, Andreas
  last_name: Heinz
- first_name: Markus
  full_name: Ralser, Markus
  last_name: Ralser
- first_name: Sven
  full_name: Twardziok, Sven
  last_name: Twardziok
- first_name: Roland
  full_name: Eils, Roland
  last_name: Eils
- first_name: Marcel
  full_name: Jentsch, Marcel
  last_name: Jentsch
- first_name: Ulrike-Helene
  full_name: Taron, Ulrike-Helene
  last_name: Taron
- first_name: Tatjana
  full_name: Schütz, Tatjana
  last_name: Schütz
- first_name: Kerstin
  full_name: Schepanski, Kerstin
  last_name: Schepanski
- first_name: Tobias
  full_name: Banaschewski, Tobias
  last_name: Banaschewski
- first_name: Maja
  full_name: Neidhart, Maja
  last_name: Neidhart
- first_name: Andreas
  full_name: Meyer-Lindenberg, Andreas
  last_name: Meyer-Lindenberg
- first_name: Heike
  full_name: Tost, Heike
  last_name: Tost
- first_name: Nathalie
  full_name: Holz, Nathalie
  last_name: Holz
- first_name: Emanuel
  full_name: Schwarz, Emanuel
  last_name: Schwarz
- first_name: Argyris
  full_name: Stringaris, Argyris
  last_name: Stringaris
- first_name: Nina
  full_name: Christmann, Nina
  last_name: Christmann
- first_name: Karina
  full_name: Janson, Karina
  last_name: Janson
- first_name: Frauke
  full_name: Nees, Frauke
  last_name: Nees
- first_name: Maja
  full_name: Neidhart, Maja
  last_name: Neidhart
- first_name: Beke
  full_name: Seefried, Beke
  last_name: Seefried
- first_name: Rieke
  full_name: Aden, Rieke
  last_name: Aden
- first_name: Ole A.
  full_name: Andreassen, Ole A.
  last_name: Andreassen
- first_name: Lars T.
  full_name: Westlye, Lars T.
  last_name: Westlye
- first_name: Dennis
  full_name: van der Meer, Dennis
  last_name: van der Meer
- first_name: Sara
  full_name: Fernández-Cabello, Sara
  last_name: Fernández-Cabello
- first_name: Rikka
  full_name: Kjelkenes, Rikka
  last_name: Kjelkenes
- first_name: Helga
  full_name: Ask, Helga
  last_name: Ask
- first_name: Michael
  full_name: Rapp, Michael
  last_name: Rapp
- first_name: Mira
  full_name: Tschorn, Mira
  last_name: Tschorn
- first_name: Sarah Jane
  full_name: Böttger, Sarah Jane
  last_name: Böttger
- first_name: Andre
  full_name: Marquand, Andre
  last_name: Marquand
- first_name: Antoine
  full_name: Bernas, Antoine
  last_name: Bernas
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Mel
  full_name: Slater, Mel
  last_name: Slater
- first_name: Jaime
  full_name: Gallego, Jaime
  last_name: Gallego
- first_name: Álvaro
  full_name: Pastor, Álvaro
  last_name: Pastor
- first_name: Guillem
  full_name: Feixas, Guillem
  last_name: Feixas
- first_name: Francisco José
  full_name: Eiroa-Orosa, Francisco José
  last_name: Eiroa-Orosa
- first_name: Markus M.
  full_name: Nöthen, Markus M.
  last_name: Nöthen
- first_name: Andreas J.
  full_name: Forstner, Andreas J.
  last_name: Forstner
- first_name: Isabelle
  full_name: Claus, Isabelle
  last_name: Claus
- first_name: Carina
  full_name: Mathey, Carina
  last_name: Mathey
- first_name: Stefanie
  full_name: Heilmann-Heimbach, Stefanie
  last_name: Heilmann-Heimbach
- first_name: Per
  full_name: Hoffmann, Per
  last_name: Hoffmann
- first_name: Abigail
  full_name: Miller, Abigail
  last_name: Miller
- first_name: Peter
  full_name: Sommer, Peter
  last_name: Sommer
- first_name: Karen
  full_name: Schmitt, Karen
  last_name: Schmitt
- first_name: Johannes
  full_name: Wilbertz, Johannes
  last_name: Wilbertz
- first_name: Myrto
  full_name: Patraskaki, Myrto
  last_name: Patraskaki
- first_name: Viktor
  full_name: Jirsa, Viktor
  last_name: Jirsa
- first_name: Spase
  full_name: Petkoski, Spase
  last_name: Petkoski
- first_name: Anastasios-Polykarpos
  full_name: Athanasiadis, Anastasios-Polykarpos
  last_name: Athanasiadis
- first_name: Bernhard
  full_name: Spanlang, Bernhard
  last_name: Spanlang
- first_name: Charlie
  full_name: Pearmund, Charlie
  last_name: Pearmund
- first_name: Sören
  full_name: Hese, Sören
  last_name: Hese
- first_name: Paul
  full_name: Renner, Paul
  last_name: Renner
- first_name: Tianye
  full_name: Jia, Tianye
  last_name: Jia
- first_name: Xiao
  full_name: Chang, Xiao
  last_name: Chang
- first_name: Yuxiang
  full_name: Dai, Yuxiang
  last_name: Dai
- first_name: Yunman
  full_name: Xia, Yunman
  last_name: Xia
- first_name: Yuzhu
  full_name: Li, Yuzhu
  last_name: Li
- first_name: Yanqing
  full_name: Zhang, Yanqing
  last_name: Zhang
- first_name: Vince
  full_name: Calhoun, Vince
  last_name: Calhoun
- first_name: Paul
  full_name: Thompson, Paul
  last_name: Thompson
- first_name: Nicholas
  full_name: Clinton, Nicholas
  last_name: Clinton
- first_name: Sylvane
  full_name: Desrivières, Sylvane
  last_name: Desrivières
- first_name: Kofoworola
  full_name: Agunbiade, Kofoworola
  last_name: Agunbiade
- first_name: Xinyang
  full_name: Yu, Xinyang
  last_name: Yu
- first_name: Zuo
  full_name: Zhang, Zuo
  last_name: Zhang
- first_name: Di
  full_name: Chen, Di
  last_name: Chen
- first_name: Allan H.
  full_name: Young, Allan H.
  last_name: Young
- first_name: Ameli
  full_name: Schwalber, Ameli
  last_name: Schwalber
- first_name: Vanessa
  full_name: Köhler, Vanessa
  last_name: Köhler
- first_name: Bernd
  full_name: Stahl, Bernd
  last_name: Stahl
- first_name: George
  full_name: Ogoh, George
  last_name: Ogoh
- first_name: Tamara
  full_name: Schikowski, Tamara
  last_name: Schikowski
- first_name: Ragnhild
  full_name: Brandlistuen, Ragnhild
  last_name: Brandlistuen
citation:
  ama: Liang C, Yuan J, Zhang R, et al. Projecting the morbidity burden of mental
    and behavioral disorders associated with increasing humid heat in Shanghai. <i>Nature
    Mental Health</i>. 2025;3(12):1532-1544. doi:<a href="https://doi.org/10.1038/s44220-025-00519-y">10.1038/s44220-025-00519-y</a>
  apa: Liang, C., Yuan, J., Zhang, R., Tang, X., Schumann, G., Hitchen, E., … Brandlistuen,
    R. (2025). Projecting the morbidity burden of mental and behavioral disorders
    associated with increasing humid heat in Shanghai. <i>Nature Mental Health</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s44220-025-00519-y">https://doi.org/10.1038/s44220-025-00519-y</a>
  chicago: Liang, Chen, Jiacan Yuan, Renhe Zhang, Xu Tang, Gunter Schumann, Esther
    Hitchen, Elli Polemiti, et al. “Projecting the Morbidity Burden of Mental and
    Behavioral Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature
    Mental Health</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s44220-025-00519-y">https://doi.org/10.1038/s44220-025-00519-y</a>.
  ieee: C. Liang <i>et al.</i>, “Projecting the morbidity burden of mental and behavioral
    disorders associated with increasing humid heat in Shanghai,” <i>Nature Mental
    Health</i>, vol. 3, no. 12. Springer Nature, pp. 1532–1544, 2025.
  ista: Liang C, Yuan J, Zhang R, Tang X, Schumann G, Hitchen E, Polemiti E, Serin
    E, Kebir H, Lett TA, Vaidya N, Roy J-C, Walter H, Heinz A, Ralser M, Twardziok
    S, Eils R, Jentsch M, Taron U-H, Schütz T, Schepanski K, Banaschewski T, Neidhart
    M, Meyer-Lindenberg A, Tost H, Holz N, Schwarz E, Stringaris A, Christmann N,
    Janson K, Nees F, Neidhart M, Seefried B, Aden R, Andreassen OA, Westlye LT, van
    der Meer D, Fernández-Cabello S, Kjelkenes R, Ask H, Rapp M, Tschorn M, Böttger
    SJ, Marquand A, Bernas A, Novarino G, Slater M, Gallego J, Pastor Á, Feixas G,
    Eiroa-Orosa FJ, Nöthen MM, Forstner AJ, Claus I, Mathey C, Heilmann-Heimbach S,
    Hoffmann P, Miller A, Sommer P, Schmitt K, Wilbertz J, Patraskaki M, Jirsa V,
    Petkoski S, Athanasiadis A-P, Spanlang B, Pearmund C, Hese S, Renner P, Jia T,
    Chang X, Dai Y, Xia Y, Li Y, Zhang Y, Calhoun V, Thompson P, Clinton N, Desrivières
    S, Agunbiade K, Yu X, Zhang Z, Chen D, Young AH, Schwalber A, Köhler V, Stahl
    B, Ogoh G, Schikowski T, Brandlistuen R. 2025. Projecting the morbidity burden
    of mental and behavioral disorders associated with increasing humid heat in Shanghai.
    Nature Mental Health. 3(12), 1532–1544.
  mla: Liang, Chen, et al. “Projecting the Morbidity Burden of Mental and Behavioral
    Disorders Associated with Increasing Humid Heat in Shanghai.” <i>Nature Mental
    Health</i>, vol. 3, no. 12, Springer Nature, 2025, pp. 1532–44, doi:<a href="https://doi.org/10.1038/s44220-025-00519-y">10.1038/s44220-025-00519-y</a>.
  short: C. Liang, J. Yuan, R. Zhang, X. Tang, G. Schumann, E. Hitchen, E. Polemiti,
    E. Serin, H. Kebir, T.A. Lett, N. Vaidya, J.-C. Roy, H. Walter, A. Heinz, M. Ralser,
    S. Twardziok, R. Eils, M. Jentsch, U.-H. Taron, T. Schütz, K. Schepanski, T. Banaschewski,
    M. Neidhart, A. Meyer-Lindenberg, H. Tost, N. Holz, E. Schwarz, A. Stringaris,
    N. Christmann, K. Janson, F. Nees, M. Neidhart, B. Seefried, R. Aden, O.A. Andreassen,
    L.T. Westlye, D. van der Meer, S. Fernández-Cabello, R. Kjelkenes, H. Ask, M.
    Rapp, M. Tschorn, S.J. Böttger, A. Marquand, A. Bernas, G. Novarino, M. Slater,
    J. Gallego, Á. Pastor, G. Feixas, F.J. Eiroa-Orosa, M.M. Nöthen, A.J. Forstner,
    I. Claus, C. Mathey, S. Heilmann-Heimbach, P. Hoffmann, A. Miller, P. Sommer,
    K. Schmitt, J. Wilbertz, M. Patraskaki, V. Jirsa, S. Petkoski, A.-P. Athanasiadis,
    B. Spanlang, C. Pearmund, S. Hese, P. Renner, T. Jia, X. Chang, Y. Dai, Y. Xia,
    Y. Li, Y. Zhang, V. Calhoun, P. Thompson, N. Clinton, S. Desrivières, K. Agunbiade,
    X. Yu, Z. Zhang, D. Chen, A.H. Young, A. Schwalber, V. Köhler, B. Stahl, G. Ogoh,
    T. Schikowski, R. Brandlistuen, Nature Mental Health 3 (2025) 1532–1544.
date_created: 2025-12-29T12:11:28Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-01-05T12:02:29Z
day: '01'
department:
- _id: GaNo
doi: 10.1038/s44220-025-00519-y
intvolume: '         3'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 1532-1544
project:
- _id: 349d1832-11ca-11ed-8bc3-d79b574010e0
  grant_number: '101057429'
  name: Reducing the impact of major environmental challenges on mental health
publication: Nature Mental Health
publication_identifier:
  issn:
  - 2731-6076
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Projecting the morbidity burden of mental and behavioral disorders associated
  with increasing humid heat in Shanghai
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2025'
...
---
OA_type: closed access
_id: '20869'
abstract:
- lang: eng
  text: "Premise: What maintains trait divergence in the face of gene flow? Two varieties
    of wild snapdragon (Antirrhinum majus) characterized by divergent flower color
    hybridize in their native range. Selection on flower color genes is indicated
    by sharp clines, but the selective agents have not been demonstrated. Although
    previous work has focused on pollinators, pigmentation genes can also contribute
    to abiotic stress tolerance. We hypothesized that pigmentation in A. majus mediates
    stress tolerance, which could contribute to hybrid zone maintenance through parental
    niche divergence or hybrid maladaptation. Specifically, we tested whether morphotype
    mediates drought tolerance in an experiment comparing magenta-flowered var. pseudomajus,
    yellow-flowered var. striatum, and their pink-flowered hybrid cross.\r\nMethods:
    We experimentally compared drought tolerance of each morphotype from allopatric
    crosses within and between varieties using three greenhouse treatments. Control
    plants were watered as needed, while drought-treated plants were watered half
    as often, either from the transplant stage (“early” drought), or from flowering
    onset (“late” drought).\r\nResults: Parental morphotypes responded identically
    to drought in fitness and most phenotypic traits. However, hybrids had lower survival
    (14%) under late drought stress than parental morphotypes (70%). All hybrids that
    flowered in the late drought treatment died, compared to ~20% of flowering parental
    morphotypes.\r\nConclusions: Hybrid maladaptation to abiotic stress could potentially
    contribute to flower color divergence in the face of gene flow in A. majus. Further
    research should test the relevance of our results to field conditions and explicitly
    probe the role of flower color genes in drought tolerance."
acknowledgement: Thank you to Doug Schemske and Nick Barton forcritically reviewing
  the manuscript, Beatriz Pablo Car-mona for assisting with data collection, Melinda
  Pickupand Eva Cereghetti for seedlings, and Louise Arathoon,Ksenia Khudiakova, Georg
  Rieckh, Daria Shiplina, andAnja Westram for help with experimental maintenance.We
  sincerely thank the Associate Editor Brenda Grewelland two anonymous reviewers for
  their thoughtfulcomments and suggestions, which substantially improved the clarity
  and quality of our manuscript. C.B. receivedfunding from the European Union's Horizon
  2020 researchand innovation programme under the Marie Skłodowska‐Curie Grant Agreement
  No. 754411
article_number: e70129
article_processing_charge: No
article_type: original
author:
- first_name: Alexandre
  full_name: Fuster‐Calvo, Alexandre
  last_name: Fuster‐Calvo
- first_name: Coline C.
  full_name: Jaworski, Coline C.
  last_name: Jaworski
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
- first_name: Carina
  full_name: Baskett, Carina
  id: 3B4A7CE2-F248-11E8-B48F-1D18A9856A87
  last_name: Baskett
  orcid: 0000-0002-7354-8574
citation:
  ama: Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. Reduced fitness under drought
    stress in F1 hybrids of Antirrhinum majus varieties with divergent flower colors.
    <i>American Journal of Botany</i>. 2025;112(12). doi:<a href="https://doi.org/10.1002/ajb2.70129">10.1002/ajb2.70129</a>
  apa: Fuster‐Calvo, A., Jaworski, C. C., Ellis, T., &#38; Baskett, C. (2025). Reduced
    fitness under drought stress in F1 hybrids of Antirrhinum majus varieties with
    divergent flower colors. <i>American Journal of Botany</i>. Wiley. <a href="https://doi.org/10.1002/ajb2.70129">https://doi.org/10.1002/ajb2.70129</a>
  chicago: Fuster‐Calvo, Alexandre, Coline C. Jaworski, Thomas Ellis, and Carina Baskett.
    “Reduced Fitness under Drought Stress in F1 Hybrids of Antirrhinum Majus Varieties
    with Divergent Flower Colors.” <i>American Journal of Botany</i>. Wiley, 2025.
    <a href="https://doi.org/10.1002/ajb2.70129">https://doi.org/10.1002/ajb2.70129</a>.
  ieee: A. Fuster‐Calvo, C. C. Jaworski, T. Ellis, and C. Baskett, “Reduced fitness
    under drought stress in F1 hybrids of Antirrhinum majus varieties with divergent
    flower colors,” <i>American Journal of Botany</i>, vol. 112, no. 12. Wiley, 2025.
  ista: Fuster‐Calvo A, Jaworski CC, Ellis T, Baskett C. 2025. Reduced fitness under
    drought stress in F1 hybrids of Antirrhinum majus varieties with divergent flower
    colors. American Journal of Botany. 112(12), e70129.
  mla: Fuster‐Calvo, Alexandre, et al. “Reduced Fitness under Drought Stress in F1
    Hybrids of Antirrhinum Majus Varieties with Divergent Flower Colors.” <i>American
    Journal of Botany</i>, vol. 112, no. 12, e70129, Wiley, 2025, doi:<a href="https://doi.org/10.1002/ajb2.70129">10.1002/ajb2.70129</a>.
  short: A. Fuster‐Calvo, C.C. Jaworski, T. Ellis, C. Baskett, American Journal of
    Botany 112 (2025).
date_created: 2025-12-29T12:14:26Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-01-05T11:56:22Z
day: '01'
department:
- _id: NiBa
doi: 10.1002/ajb2.70129
ec_funded: 1
external_id:
  pmid:
  - '41327576 '
intvolume: '       112'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: American Journal of Botany
publication_identifier:
  eissn:
  - 1537-2197
  issn:
  - 0002-9122
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/Alex-Fuster/hybrids_drought
scopus_import: '1'
status: public
title: Reduced fitness under drought stress in F1 hybrids of Antirrhinum majus varieties
  with divergent flower colors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20925'
abstract:
- lang: eng
  text: 'We prove normal typicality and dynamical typicality for a (centered) random
    block-band matrix model with block-dependent variances. A key feature of our model
    is that we achieve intermediate equilibration times, an aspect that has not been
    proven rigorously in any model before. Our proof builds on recently established
    concentration estimates for products of resolvents of Wigner type random matrices
    (Erdős and Riabov in Commun Math Phys 405(12): 282, 2024) and an intricate analysis
    of the deterministic approximation.'
acknowledgement: L.E. and J.H. are supported by the ERC Advanced Grant “RMTBeyond”
  No. 101020331. Moreover, J.H. acknowledges (partial) financial support by the ERC
  Consolidator Grant “ProbQuant” (jointly with the Swiss State Secretariat for Education,
  Research and Innovation). C.V. was (partially) supported by the German Academic
  Scholarship Foundation and the Deutsche Forschungsgemeinschaft (DFG, German Research
  Foundation) – TRR 352 – Project-ID 470903074. Moreover, C.V. acknowledges (partial)
  financial support by the ERC Starting Grant “FermiMath" No. 101040991 and the ERC
  Consolidator Grant “RAMBAS” No. 10104424, funded by the European Union. Open access
  funding provided by Institute of Science and Technology (IST Austria).
article_number: '5'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Cornelia
  full_name: Vogel, Cornelia
  id: 1cd0554a-ea28-11f0-9f40-ff76440883cd
  last_name: Vogel
citation:
  ama: Erdös L, Henheik SJ, Vogel C. Normal typicality and dynamical typicality for
    a random block-band matrix model. <i>Letters in Mathematical Physics</i>. 2025;116.
    doi:<a href="https://doi.org/10.1007/s11005-025-02037-5">10.1007/s11005-025-02037-5</a>
  apa: Erdös, L., Henheik, S. J., &#38; Vogel, C. (2025). Normal typicality and dynamical
    typicality for a random block-band matrix model. <i>Letters in Mathematical Physics</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s11005-025-02037-5">https://doi.org/10.1007/s11005-025-02037-5</a>
  chicago: Erdös, László, Sven Joscha Henheik, and Cornelia Vogel. “Normal Typicality
    and Dynamical Typicality for a Random Block-Band Matrix Model.” <i>Letters in
    Mathematical Physics</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s11005-025-02037-5">https://doi.org/10.1007/s11005-025-02037-5</a>.
  ieee: L. Erdös, S. J. Henheik, and C. Vogel, “Normal typicality and dynamical typicality
    for a random block-band matrix model,” <i>Letters in Mathematical Physics</i>,
    vol. 116. Springer Nature, 2025.
  ista: Erdös L, Henheik SJ, Vogel C. 2025. Normal typicality and dynamical typicality
    for a random block-band matrix model. Letters in Mathematical Physics. 116, 5.
  mla: Erdös, László, et al. “Normal Typicality and Dynamical Typicality for a Random
    Block-Band Matrix Model.” <i>Letters in Mathematical Physics</i>, vol. 116, 5,
    Springer Nature, 2025, doi:<a href="https://doi.org/10.1007/s11005-025-02037-5">10.1007/s11005-025-02037-5</a>.
  short: L. Erdös, S.J. Henheik, C. Vogel, Letters in Mathematical Physics 116 (2025).
corr_author: '1'
date_created: 2026-01-04T23:01:33Z
date_published: 2025-12-26T00:00:00Z
date_updated: 2026-01-05T11:22:25Z
day: '26'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s11005-025-02037-5
ec_funded: 1
external_id:
  pmid:
  - '41459414'
has_accepted_license: '1'
intvolume: '       116'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s11005-025-02037-5
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Letters in Mathematical Physics
publication_identifier:
  eissn:
  - 1573-0530
  issn:
  - 0377-9017
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Normal typicality and dynamical typicality for a random block-band matrix model
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20929'
abstract:
- lang: eng
  text: Insulin/insulin-like growth factor signaling inhibits FOXO transcription factors
    to control development, homeostasis, and aging. Here, we use proximity labeling
    to identify proteins interacting with the C. elegans FOXO DAF-16. We show that
    in well-fed, unstressed animals harboring active insulin signaling, DAF-16 forms
    a complex with the PAR-1/MARK serine/threonine kinase, a key regulator of cell
    polarity. PAR-1 inhibits DAF-16 accumulation and promotes DAF-16 phosphorylation
    at S249, at a conserved motif that PAR-1/human MARK2 phosphorylates in vitro.
    DAF-2 insulin-like receptor signaling stimulates DAF-16 S249 phosphorylation,
    suggesting DAF-2 activates PAR-1. DAF-2 also promotes PAR-1 expression by inhibiting
    DAF-16. PAR-1 knockdown, or DAF-16 S249A, prolong lifespan, whereas phosphomimetic
    DAF-16 S249D suppresses the longevity of daf-2 mutants. At low insulin signaling,
    DAF-16 proximity labeling highlights transcription factors, chromatin regulators,
    and DNA repair proteins. One interactor, the zinc finger/homeobox protein ZFH-2/ZFHX3,
    forms a complex with DAF-16 and prolongs lifespan. Our work provides entry points
    for hypothesis-driven studies of FOXO function and longevity.
acknowledged_ssus:
- _id: Bio
acknowledgement: We thank de Bono lab members for helpful comments on the manuscript,
  and the Mass Spec Facility at the Max Perutz Labs, notably WeiQiang Chen and Markus
  Hartl, for invaluable discussions and comments on mass spec analyses of worm samples.
  All LC-MS/MS analyses were performed on instruments of the Vienna BioCenter Core
  Facilities (VBCF). Microscopy was supported by the Scientific Services Units (SSU)
  of ISTA through resources provided by the Imaging & Optics Facility (IOF). We are
  grateful to Dr. Geraldine Seydoux (Johns Hopkins University) for worm strains and
  plasmids, and Dr. Seung-Jae V. Lee (KAIST) for RNAi clones. We are grateful to Ekaterina
  Lashmanova for designing the daf-16::TbID::mNG::3xFLAG knock-in construct and for
  her outstanding support in the lab. This work was supported by a Wellcome Investigator
  Award (209504/A/17/Z) to MdB and an ISTplus Fellowship to MA (Marie Sklodowska-Curie
  agreement No 754411).
article_number: '11355'
article_processing_charge: Yes
article_type: original
author:
- first_name: Murat
  full_name: Artan, Murat
  id: C407B586-6052-11E9-B3AE-7006E6697425
  last_name: Artan
  orcid: 0000-0001-8945-6992
- first_name: Hanna
  full_name: Schön, Hanna
  id: C8E17EDC-D7AA-11E9-B7B7-45ECE5697425
  last_name: Schön
- first_name: Mario
  full_name: De Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: De Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Artan M, Schön H, de Bono M. Proximity labeling of DAF-16 FOXO highlights aging
    regulatory proteins. <i>Nature Communications</i>. 2025;16. doi:<a href="https://doi.org/10.1038/s41467-025-66409-0">10.1038/s41467-025-66409-0</a>
  apa: Artan, M., Schön, H., &#38; de Bono, M. (2025). Proximity labeling of DAF-16
    FOXO highlights aging regulatory proteins. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-025-66409-0">https://doi.org/10.1038/s41467-025-66409-0</a>
  chicago: Artan, Murat, Hanna Schön, and Mario de Bono. “Proximity Labeling of DAF-16
    FOXO Highlights Aging Regulatory Proteins.” <i>Nature Communications</i>. Springer
    Nature, 2025. <a href="https://doi.org/10.1038/s41467-025-66409-0">https://doi.org/10.1038/s41467-025-66409-0</a>.
  ieee: M. Artan, H. Schön, and M. de Bono, “Proximity labeling of DAF-16 FOXO highlights
    aging regulatory proteins,” <i>Nature Communications</i>, vol. 16. Springer Nature,
    2025.
  ista: Artan M, Schön H, de Bono M. 2025. Proximity labeling of DAF-16 FOXO highlights
    aging regulatory proteins. Nature Communications. 16, 11355.
  mla: Artan, Murat, et al. “Proximity Labeling of DAF-16 FOXO Highlights Aging Regulatory
    Proteins.” <i>Nature Communications</i>, vol. 16, 11355, Springer Nature, 2025,
    doi:<a href="https://doi.org/10.1038/s41467-025-66409-0">10.1038/s41467-025-66409-0</a>.
  short: M. Artan, H. Schön, M. de Bono, Nature Communications 16 (2025).
corr_author: '1'
date_created: 2026-01-04T23:01:34Z
date_published: 2025-12-11T00:00:00Z
date_updated: 2026-01-05T11:00:03Z
day: '11'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1038/s41467-025-66409-0
ec_funded: 1
external_id:
  pmid:
  - '41381452'
file:
- access_level: open_access
  checksum: 748e2e003b878b85b6048d51621d6aae
  content_type: application/pdf
  creator: dernst
  date_created: 2026-01-05T10:58:28Z
  date_updated: 2026-01-05T10:58:28Z
  file_id: '20941'
  file_name: 2025_NatureComm_Artan.pdf
  file_size: 1642352
  relation: main_file
  success: 1
file_date_updated: 2026-01-05T10:58:28Z
has_accepted_license: '1'
intvolume: '        16'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 23870BE8-32DE-11EA-91FC-C7463DDC885E
  grant_number: 209504/A/17/Z
  name: Molecular mechanisms of neural circuit function
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Proximity labeling of DAF-16 FOXO highlights aging regulatory proteins
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20935'
abstract:
- lang: eng
  text: In situ cryo-electron tomography (cryo-ET) has emerged as the method of choice
    to investigate the structures of biomolecules in their native context. However,
    challenges remain for the efficient production and sharing of large-scale cryo-ET
    datasets. Here, we combined cryogenic plasma-based focused ion beam (cryo-PFIB)
    milling with recent advances in cryo-ET acquisition and processing to generate
    a dataset of 1,829 annotated tomograms of the green alga Chlamydomonas reinhardtii,
    which we provide as a community resource to drive method development and inspire
    biological discovery. To assay data quality, we performed subtomogram averaging
    of both soluble and membrane-bound complexes ranging in size from >3 MDa to ∼200
    kDa, including 80S ribosomes, Rubisco, nucleosomes, microtubules, clathrin, photosystem
    II, and mitochondrial ATP synthase. The majority of these density maps reached
    sub-nanometer resolution, demonstrating the potential of this C. reinhardtii dataset
    as well as the promise of modern cryo-ET workflows and open data sharing to empower
    visual proteomics.
acknowledgement: Calculations were performed at the Max Planck Institute of Biochemistry
  and the Raven Supercomputer of the Max Planck Computing and Data Facility (MPCDF)
  in Garching, Germany; at the sciCORE (http://scicore.unibas.ch/) scientific computing
  center at the University of Basel, Switzerland; and at Thermo Fisher Scientific,
  in Eindhoven, the Netherlands. This work was supported by Thermo Fisher Scientific.
  All lamella preparations and tilt-series collections used in this work were conducted
  at Thermo Fisher R&D facilities in Brno and Eindhoven, utilizing Arctis and Krios
  microscopes. This work was also supported by the ERC consolidator grant “cryOcean”
  (fulfilled by the Swiss State Secretariat for Education, Research and Innovation,
  M822.00045) as well as a Swiss Nanoscience Institute PhD school grant to B.D.E.
  and P.V.d.S., an EMBO long-term postdoctoral fellowship (ALTF-383-2022) to G.T.,
  an SNSF Postdoctoral Fellowship (project 210561) to F.W., a Boehringer Ingelheim
  Fonds fellowship to L.L., and by the Max Planck Society to J.A.G.B. and J.M.P.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Ron
  full_name: Kelley, Ron
  last_name: Kelley
- first_name: Sagar
  full_name: Khavnekar, Sagar
  last_name: Khavnekar
- first_name: Ricardo D.
  full_name: Righetto, Ricardo D.
  last_name: Righetto
- first_name: Jessica
  full_name: Heebner, Jessica
  last_name: Heebner
- first_name: Martin
  full_name: Obr, Martin
  id: 4741CA5A-F248-11E8-B48F-1D18A9856A87
  last_name: Obr
  orcid: 0000-0003-1756-6564
- first_name: Xianjun
  full_name: Zhang, Xianjun
  last_name: Zhang
- first_name: Saikat
  full_name: Chakraborty, Saikat
  last_name: Chakraborty
- first_name: Grigory
  full_name: Tagiltsev, Grigory
  last_name: Tagiltsev
- first_name: Alicia
  full_name: Michael, Alicia
  id: 6437c950-2a03-11ee-914d-d6476dd7b75c
  last_name: Michael
  orcid: 0000-0002-6080-839X
- first_name: Sofie
  full_name: Van Dorst, Sofie
  last_name: Van Dorst
- first_name: Florent
  full_name: Waltz, Florent
  last_name: Waltz
- first_name: Caitlyn L.
  full_name: Mccafferty, Caitlyn L.
  last_name: Mccafferty
- first_name: Lorenz
  full_name: Lamm, Lorenz
  last_name: Lamm
- first_name: Simon
  full_name: Zufferey, Simon
  last_name: Zufferey
- first_name: Philippe
  full_name: Van Der Stappen, Philippe
  last_name: Van Der Stappen
- first_name: Hugo
  full_name: Van Den Hoek, Hugo
  last_name: Van Den Hoek
- first_name: Wojciech
  full_name: Wietrzynski, Wojciech
  last_name: Wietrzynski
- first_name: Pavol
  full_name: Harar, Pavol
  id: e03d953a-6e8c-11ef-99e4-f0717d385cd5
  last_name: Harar
  orcid: 0000-0001-5206-1794
- first_name: William
  full_name: Wan, William
  last_name: Wan
- first_name: John A.G.
  full_name: Briggs, John A.G.
  last_name: Briggs
- first_name: Jürgen M.
  full_name: Plitzko, Jürgen M.
  last_name: Plitzko
- first_name: Benjamin D.
  full_name: Engel, Benjamin D.
  last_name: Engel
- first_name: Abhay
  full_name: Kotecha, Abhay
  last_name: Kotecha
citation:
  ama: Kelley R, Khavnekar S, Righetto RD, et al. Toward community-driven visual proteomics
    with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. <i>Molecular
    Cell</i>. doi:<a href="https://doi.org/10.1016/j.molcel.2025.11.029">10.1016/j.molcel.2025.11.029</a>
  apa: Kelley, R., Khavnekar, S., Righetto, R. D., Heebner, J., Obr, M., Zhang, X.,
    … Kotecha, A. (n.d.). Toward community-driven visual proteomics with large-scale
    cryo-electron tomography of Chlamydomonas reinhardtii. <i>Molecular Cell</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.molcel.2025.11.029">https://doi.org/10.1016/j.molcel.2025.11.029</a>
  chicago: Kelley, Ron, Sagar Khavnekar, Ricardo D. Righetto, Jessica Heebner, Martin
    Obr, Xianjun Zhang, Saikat Chakraborty, et al. “Toward Community-Driven Visual
    Proteomics with Large-Scale Cryo-Electron Tomography of Chlamydomonas Reinhardtii.”
    <i>Molecular Cell</i>. Elsevier, n.d. <a href="https://doi.org/10.1016/j.molcel.2025.11.029">https://doi.org/10.1016/j.molcel.2025.11.029</a>.
  ieee: R. Kelley <i>et al.</i>, “Toward community-driven visual proteomics with large-scale
    cryo-electron tomography of Chlamydomonas reinhardtii,” <i>Molecular Cell</i>.
    Elsevier.
  ista: Kelley R, Khavnekar S, Righetto RD, Heebner J, Obr M, Zhang X, Chakraborty
    S, Tagiltsev G, Michael AK, Van Dorst S, Waltz F, Mccafferty CL, Lamm L, Zufferey
    S, Van Der Stappen P, Van Den Hoek H, Wietrzynski W, Harar P, Wan W, Briggs JAG,
    Plitzko JM, Engel BD, Kotecha A. Toward community-driven visual proteomics with
    large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell.
  mla: Kelley, Ron, et al. “Toward Community-Driven Visual Proteomics with Large-Scale
    Cryo-Electron Tomography of Chlamydomonas Reinhardtii.” <i>Molecular Cell</i>,
    Elsevier, doi:<a href="https://doi.org/10.1016/j.molcel.2025.11.029">10.1016/j.molcel.2025.11.029</a>.
  short: R. Kelley, S. Khavnekar, R.D. Righetto, J. Heebner, M. Obr, X. Zhang, S.
    Chakraborty, G. Tagiltsev, A.K. Michael, S. Van Dorst, F. Waltz, C.L. Mccafferty,
    L. Lamm, S. Zufferey, P. Van Der Stappen, H. Van Den Hoek, W. Wietrzynski, P.
    Harar, W. Wan, J.A.G. Briggs, J.M. Plitzko, B.D. Engel, A. Kotecha, Molecular
    Cell (n.d.).
date_created: 2026-01-04T23:01:36Z
date_published: 2025-12-19T00:00:00Z
date_updated: 2026-01-05T08:32:47Z
day: '19'
ddc:
- '570'
department:
- _id: AlMi
doi: 10.1016/j.molcel.2025.11.029
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.molcel.2025.11.029
month: '12'
oa: 1
oa_version: Published Version
publication: Molecular Cell
publication_identifier:
  eissn:
  - 1097-4164
  issn:
  - 1097-2765
publication_status: inpress
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Toward community-driven visual proteomics with large-scale cryo-electron tomography
  of Chlamydomonas reinhardtii
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_type: closed access
_id: '20973'
abstract:
- lang: eng
  text: CuAgSe-based materials are attractive for low-temperature thermoelectric (TE)
    applications but are limited by bipolar conduction and relatively high thermal
    conductivity. Herein, we report a ligand-free aqueous synthesis of Te-doped CuAgSe
    (CuAgSe1-xTex), where structural and electronic modulation improve carrier transport
    and suppress phonon propagation. Ex-situ time-resolved X-ray diffraction reveals
    a spontaneous growth mechanism, while density functional theory calculations show
    that Te-5s and 5p orbitals hybridization generates localized states and an asymmetric
    density of states, thereby enhancing the Seebeck coefficient. Electron microscopy
    and strain analyses confirm that Te-doping introduces a high density of lattice
    dislocations and grain boundaries, leading to a reduced lattice thermal conductivity
    of 0.11 W m−1K−1 at 443 K. These synergistic effects translate into device-level
    performance—the first integrated CuAgSe thermoelectric modules, exhibit a maximum
    cooling temperature difference of 27.3 K, and power density of 0.34 W cm−2 with
    a conversion efficiency of 3.6% at a modest temperature gradient of 136 K. These
    results demonstrate that CuAgSe1-xTex enables efficient energy harvesting and
    localized cooling under small temperature gradient, underscoring the importance
    of structural and electronic design beyond conventional zT benchmarks.
acknowledgement: K.H.L. acknowledges financial support from the National Natural Science
  Foundation of China (NSFC) (Grant Number 22208293) and the National Foreign Expert
  Project (Y20240175). Y.L. acknowledges funding from the NSFC (Grant Number 22209034),
  the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province
  (Grant Number 2022LCX002), and the Fundamental Research Funds for the Central Universities
  (JZ2024HGTB0239). Y.Z. acknowledges funding from the NSFC (Grant Number 52502313)
  and Wenzhou Basic Scientific Research Project (Grant Number G20240034). Q. W. acknowledges
  financial support from the NSFC (Grant Number 22208292), the High-Level Overseas-Educated
  Talents Return Program, and the “Pioneer” and “Leading Goose” R&D Program of Zhejiang
  [2025C04021]. K.H.L., Q. W., and X. Y. also acknowledge the Research Funds of the
  Institute of Zhejiang University-Quzhou (Grants No. IZQ2022RCZX101, IZQ2021RCZX003,
  IZQ2021RCZX002, and IZQ2024KJ0004). M.H. acknowledges the funding from the Australian
  Research Council and the iLAuNCH Trailblazer, Department of Education, Australia.
  M.H. acknowledges the computational support from the National Computational Infrastructure
  (NCI), Australia, and Pawsey Supercomputing Centre, Australia.
article_number: e13035
article_processing_charge: No
article_type: original
author:
- first_name: Weite
  full_name: Meng, Weite
  last_name: Meng
- first_name: Mingquan
  full_name: Li, Mingquan
  last_name: Li
- first_name: Qingyue
  full_name: Wang, Qingyue
  last_name: Wang
- first_name: Pingan
  full_name: Song, Pingan
  last_name: Song
- first_name: Xuan
  full_name: Yang, Xuan
  last_name: Yang
- first_name: Wen Jun
  full_name: Wang, Wen Jun
  last_name: Wang
- first_name: Min
  full_name: Hong, Min
  last_name: Hong
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Andreu
  full_name: Cabot, Andreu
  last_name: Cabot
- first_name: Yu
  full_name: Zhang, Yu
  last_name: Zhang
- first_name: Yu
  full_name: Liu, Yu
  last_name: Liu
- first_name: Khak Ho
  full_name: Lim, Khak Ho
  last_name: Lim
citation:
  ama: Meng W, Li M, Wang Q, et al. Efficient near room temperature thermoelectric
    cooling and power generation with CuAgSe. <i>Small</i>. 2025. doi:<a href="https://doi.org/10.1002/smll.202513035">10.1002/smll.202513035</a>
  apa: Meng, W., Li, M., Wang, Q., Song, P., Yang, X., Wang, W. J., … Lim, K. H. (2025).
    Efficient near room temperature thermoelectric cooling and power generation with
    CuAgSe. <i>Small</i>. Wiley. <a href="https://doi.org/10.1002/smll.202513035">https://doi.org/10.1002/smll.202513035</a>
  chicago: Meng, Weite, Mingquan Li, Qingyue Wang, Pingan Song, Xuan Yang, Wen Jun
    Wang, Min Hong, et al. “Efficient near Room Temperature Thermoelectric Cooling
    and Power Generation with CuAgSe.” <i>Small</i>. Wiley, 2025. <a href="https://doi.org/10.1002/smll.202513035">https://doi.org/10.1002/smll.202513035</a>.
  ieee: W. Meng <i>et al.</i>, “Efficient near room temperature thermoelectric cooling
    and power generation with CuAgSe,” <i>Small</i>. Wiley, 2025.
  ista: Meng W, Li M, Wang Q, Song P, Yang X, Wang WJ, Hong M, Ibáñez M, Cabot A,
    Zhang Y, Liu Y, Lim KH. 2025. Efficient near room temperature thermoelectric cooling
    and power generation with CuAgSe. Small., e13035.
  mla: Meng, Weite, et al. “Efficient near Room Temperature Thermoelectric Cooling
    and Power Generation with CuAgSe.” <i>Small</i>, e13035, Wiley, 2025, doi:<a href="https://doi.org/10.1002/smll.202513035">10.1002/smll.202513035</a>.
  short: W. Meng, M. Li, Q. Wang, P. Song, X. Yang, W.J. Wang, M. Hong, M. Ibáñez,
    A. Cabot, Y. Zhang, Y. Liu, K.H. Lim, Small (2025).
date_created: 2026-01-11T23:01:34Z
date_published: 2025-12-30T00:00:00Z
date_updated: 2026-01-12T09:37:19Z
day: '30'
department:
- _id: MaIb
doi: 10.1002/smll.202513035
external_id:
  pmid:
  - '41470065'
language:
- iso: eng
month: '12'
oa_version: None
pmid: 1
publication: Small
publication_identifier:
  eissn:
  - 1613-6829
  issn:
  - 1613-6810
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficient near room temperature thermoelectric cooling and power generation
  with CuAgSe
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
