---
_id: '11124'
abstract:
- lang: eng
text: Ran GTPase plays important roles in nucleocytoplasmic transport in interphase
[1, 2] and in both spindle formation and nuclear envelope (NE) assembly during
mitosis [3, 4, 5]. The latter functions rely on the presence of high local concentrations
of GTP-bound Ran near mitotic chromatin [3, 4, 5]. RanGTP localization has been
proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1,
with chromatin [6, 7, 8, 9], but Ran is shown here to bind directly to chromatin
in two modes, either dependent or independent of RCC1, and, where bound, to increase
the affinity of chromatin for NE membranes. We propose that the Ran binding capacity
of chromatin contributes to localized spindle and NE assembly.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Daniel
full_name: Bilbao-Cortés, Daniel
last_name: Bilbao-Cortés
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Gernot
full_name: Längst, Gernot
last_name: Längst
- first_name: Peter B.
full_name: Becker, Peter B.
last_name: Becker
- first_name: Iain W.
full_name: Mattaj, Iain W.
last_name: Mattaj
citation:
ama: Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW. Ran binds to chromatin
by two distinct mechanisms. Current Biology. 2002;12(13):1151-1156. doi:10.1016/s0960-9822(02)00927-2
apa: Bilbao-Cortés, D., Hetzer, M., Längst, G., Becker, P. B., & Mattaj, I.
W. (2002). Ran binds to chromatin by two distinct mechanisms. Current Biology.
Elsevier BV. https://doi.org/10.1016/s0960-9822(02)00927-2
chicago: Bilbao-Cortés, Daniel, Martin Hetzer, Gernot Längst, Peter B. Becker, and
Iain W. Mattaj. “Ran Binds to Chromatin by Two Distinct Mechanisms.” Current
Biology. Elsevier BV, 2002. https://doi.org/10.1016/s0960-9822(02)00927-2.
ieee: D. Bilbao-Cortés, M. Hetzer, G. Längst, P. B. Becker, and I. W. Mattaj, “Ran
binds to chromatin by two distinct mechanisms,” Current Biology, vol. 12,
no. 13. Elsevier BV, pp. 1151–1156, 2002.
ista: Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW. 2002. Ran binds
to chromatin by two distinct mechanisms. Current Biology. 12(13), 1151–1156.
mla: Bilbao-Cortés, Daniel, et al. “Ran Binds to Chromatin by Two Distinct Mechanisms.”
Current Biology, vol. 12, no. 13, Elsevier BV, 2002, pp. 1151–56, doi:10.1016/s0960-9822(02)00927-2.
short: D. Bilbao-Cortés, M. Hetzer, G. Längst, P.B. Becker, I.W. Mattaj, Current
Biology 12 (2002) 1151–1156.
date_created: 2022-04-07T07:57:31Z
date_published: 2002-07-09T00:00:00Z
date_updated: 2022-07-18T08:58:05Z
day: '09'
doi: 10.1016/s0960-9822(02)00927-2
extern: '1'
external_id:
pmid:
- '12121625'
intvolume: ' 12'
issue: '13'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/S0960-9822(02)00927-2
month: '07'
oa: 1
oa_version: Published Version
page: 1151-1156
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ran binds to chromatin by two distinct mechanisms
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 12
year: '2002'
...
---
_id: '11123'
abstract:
- lang: eng
text: The small GTPase Ran is a key regulator of nucleocytoplasmic transport during
interphase. The asymmetric distribution of the GTP-bound form of Ran across the
nuclear envelope — that is, large quantities in the nucleus compared with small
quantities in the cytoplasm — determines the directionality of many nuclear transport
processes. Recent findings that Ran also functions in spindle formation and nuclear
envelope assembly during mitosis suggest that Ran has a general role in chromatin-centred
processes. Ran functions in these events as a signal for chromosome position.
article_processing_charge: No
article_type: original
author:
- first_name: Martin W
full_name: HETZER, Martin W
id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
last_name: HETZER
orcid: 0000-0002-2111-992X
- first_name: Oliver J.
full_name: Gruss, Oliver J.
last_name: Gruss
- first_name: Iain W.
full_name: Mattaj, Iain W.
last_name: Mattaj
citation:
ama: Hetzer M, Gruss OJ, Mattaj IW. The Ran GTPase as a marker of chromosome position
in spindle formation and nuclear envelope assembly. Nature Cell Biology.
2002;4(7):E177-E184. doi:10.1038/ncb0702-e177
apa: Hetzer, M., Gruss, O. J., & Mattaj, I. W. (2002). The Ran GTPase as a marker
of chromosome position in spindle formation and nuclear envelope assembly. Nature
Cell Biology. Springer Nature. https://doi.org/10.1038/ncb0702-e177
chicago: Hetzer, Martin, Oliver J. Gruss, and Iain W. Mattaj. “The Ran GTPase as
a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.”
Nature Cell Biology. Springer Nature, 2002. https://doi.org/10.1038/ncb0702-e177.
ieee: M. Hetzer, O. J. Gruss, and I. W. Mattaj, “The Ran GTPase as a marker of chromosome
position in spindle formation and nuclear envelope assembly,” Nature Cell Biology,
vol. 4, no. 7. Springer Nature, pp. E177–E184, 2002.
ista: Hetzer M, Gruss OJ, Mattaj IW. 2002. The Ran GTPase as a marker of chromosome
position in spindle formation and nuclear envelope assembly. Nature Cell Biology.
4(7), E177–E184.
mla: Hetzer, Martin, et al. “The Ran GTPase as a Marker of Chromosome Position in
Spindle Formation and Nuclear Envelope Assembly.” Nature Cell Biology,
vol. 4, no. 7, Springer Nature, 2002, pp. E177–84, doi:10.1038/ncb0702-e177.
short: M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) E177–E184.
date_created: 2022-04-07T07:57:19Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2022-07-18T08:58:03Z
day: '01'
doi: 10.1038/ncb0702-e177
extern: '1'
external_id:
pmid:
- '12105431'
intvolume: ' 4'
issue: '7'
keyword:
- Cell Biology
language:
- iso: eng
month: '07'
oa_version: None
page: E177-E184
pmid: 1
publication: Nature Cell Biology
publication_identifier:
eissn:
- 1476-4679
issn:
- 1465-7392
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Ran GTPase as a marker of chromosome position in spindle formation and
nuclear envelope assembly
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 4
year: '2002'
...
---
_id: '12659'
abstract:
- lang: eng
text: "For many years considerable efforts have been put into investigating and
modelling hydrological processes of mountainous catchments. On the one hand, the
complexity and intrinsically high variability of the involved processes as well
as insufficient knowledge of the underlying physical mechanisms still induce large
uncertainties in understanding observed phenomena and predicting the behaviour
of the system. On the other hand, the demand for models that are able to simulate
mountainous water resource systems is increasing because of the needs related
to both water exploitation and water conservation, which clearly call for an integrated
vision and modelling of these systems.\r\nAccordingly, this paper moves from a
brief survey of the most significant achievements in mountain hydrology to discuss
what could be future challenging issues related to the broader spectrum of questions,
which hydrologic modelling of mountainous river systems may face in the next decades.
Firstly, reference is made to existing methodologies for modelling alpine water
systems, focussing on some specific aspects that provide a basis for the discussion
of the weaknesses and perspectives of present simulation tools. The future is
thus discussed, delineating some of the research challenges that may foster a
comprehensive and integrated vision of water related issues in mountainous regions."
article_processing_charge: No
article_type: original
author:
- first_name: Paolo
full_name: Burlando, Paolo
last_name: Burlando
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Ulrich
full_name: Strasser, Ulrich
last_name: Strasser
citation:
ama: Burlando P, Pellicciotti F, Strasser U. Modelling mountainous water systems
between learning and speculating looking for challenges. Hydrology Research.
2002;33(1):47-74. doi:10.2166/nh.2002.0004
apa: Burlando, P., Pellicciotti, F., & Strasser, U. (2002). Modelling mountainous
water systems between learning and speculating looking for challenges. Hydrology
Research. IWA Publishing. https://doi.org/10.2166/nh.2002.0004
chicago: Burlando, Paolo, Francesca Pellicciotti, and Ulrich Strasser. “Modelling
Mountainous Water Systems between Learning and Speculating Looking for Challenges.”
Hydrology Research. IWA Publishing, 2002. https://doi.org/10.2166/nh.2002.0004.
ieee: P. Burlando, F. Pellicciotti, and U. Strasser, “Modelling mountainous water
systems between learning and speculating looking for challenges,” Hydrology
Research, vol. 33, no. 1. IWA Publishing, pp. 47–74, 2002.
ista: Burlando P, Pellicciotti F, Strasser U. 2002. Modelling mountainous water
systems between learning and speculating looking for challenges. Hydrology Research.
33(1), 47–74.
mla: Burlando, Paolo, et al. “Modelling Mountainous Water Systems between Learning
and Speculating Looking for Challenges.” Hydrology Research, vol. 33, no.
1, IWA Publishing, 2002, pp. 47–74, doi:10.2166/nh.2002.0004.
short: P. Burlando, F. Pellicciotti, U. Strasser, Hydrology Research 33 (2002) 47–74.
date_created: 2023-02-20T08:19:02Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-02-20T08:30:15Z
day: '01'
doi: 10.2166/nh.2002.0004
extern: '1'
intvolume: ' 33'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.2166/nh.2002.0004
month: '02'
oa: 1
oa_version: Published Version
page: 47-74
publication: Hydrology Research
publication_identifier:
eissn:
- 2224-7955
issn:
- 0029-1277
publication_status: published
publisher: IWA Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling mountainous water systems between learning and speculating looking
for challenges
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2002'
...
---
_id: '1738'
abstract:
- lang: eng
text: New dyes of the type Ru(II)(bdmpp)(bpy) [where bdmpp is 2,6-bis(3,5-dimethyl-N-pyrazoyl)pyridine
and bpy is 2,2′-bipyridine-4,4′-dicarboxylic acid] are prepared and characterized
by infra-red (IR), mass (MS) and electrospray mass spectroscopy (ES-MS) as well
as 1H NMR (1D and 2D) spectroscopies. The compounds present broad and very high
intensity MLCT absorption bands in the visible and can be chemically anchored
on TiO2 films via ester-like linkage involving carboxylato groups. These complexes
have been tested with success as potential molecular antennas in dye-sensitized
solar cells. Both opaque and transparent nanocrystalline TiO2 thin film electrodes
obtained by a doctor blade technique sensitized by these complexes were incorporated
in a sandwich type regenerative photoelectrochemical solar cell containing 0.1M
LiI +0.01M I2 in propylene carbonate as well as a platinized conductive glass
counter electrode. The cell was characterized by Raman spectroscopy under anodic
and cathodic bias. Two new vibration bands were observed in the lower frequency
region. The first one at 112 cm-1 is due to tri-iodide formed on the photoactive
electrode, and the second one at 167 cm-1 is a sign of the dye/iodide interaction
and corresponds to a vibration in a chemically stable "DI" intermediate
species. Under direct sunlight illumination (solar irradiance of 60 mW/cm2) by
using a composite polymer solid state electrolyte, the cell ITO/TiO2/[Ru(II)(bdmpp)(bpy)(NCS)](PF6)/electrolyte/Pt-ITO
produced a continuous photocurrent as high as 4.29mA/cm2, and gave IPCE values
about half of the corresponding values obtained by the standard N3 dye under the
same conditions. The photovoltage is about 600 mV and the overall energy conversion
cell's efficiency is as high as 1.72%.
author:
- first_name: Polycarpos
full_name: Falaras, Polycarpos
last_name: Falaras
- first_name: Katerina
full_name: Chryssou, Katerina
last_name: Chryssou
- first_name: Thomas
full_name: Stergiopoulos, Thomas
last_name: Stergiopoulos
- first_name: Ioannis
full_name: Arabatzis, Ioannis M
last_name: Arabatzis
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Vincent
full_name: Catalano, Vincent J
last_name: Catalano
- first_name: Raif
full_name: Kurtaran, Raif
last_name: Kurtaran
- first_name: Anne
full_name: Hugot-Le Goff, Anne
last_name: Hugot Le Goff
- first_name: Marie
full_name: Bernard, Marie C
last_name: Bernard
citation:
ama: 'Falaras P, Chryssou K, Stergiopoulos T, et al. Dye-sensitization of titanium
dioxide thin films by Ru(II)-bpp-bpy complexes. In: Vol 4801. SPIE; 2002:125-135.
doi:10.1117/12.452446'
apa: Falaras, P., Chryssou, K., Stergiopoulos, T., Arabatzis, I., Katsaros, G.,
Catalano, V., … Bernard, M. (2002). Dye-sensitization of titanium dioxide thin
films by Ru(II)-bpp-bpy complexes (Vol. 4801, pp. 125–135). Presented at the Organic
Photovoltaics, SPIE. https://doi.org/10.1117/12.452446
chicago: Falaras, Polycarpos, Katerina Chryssou, Thomas Stergiopoulos, Ioannis Arabatzis,
Georgios Katsaros, Vincent Catalano, Raif Kurtaran, Anne Hugot Le Goff, and Marie
Bernard. “Dye-Sensitization of Titanium Dioxide Thin Films by Ru(II)-Bpp-Bpy Complexes,”
4801:125–35. SPIE, 2002. https://doi.org/10.1117/12.452446.
ieee: P. Falaras et al., “Dye-sensitization of titanium dioxide thin films
by Ru(II)-bpp-bpy complexes,” presented at the Organic Photovoltaics, 2002, vol.
4801, pp. 125–135.
ista: Falaras P, Chryssou K, Stergiopoulos T, Arabatzis I, Katsaros G, Catalano
V, Kurtaran R, Hugot Le Goff A, Bernard M. 2002. Dye-sensitization of titanium
dioxide thin films by Ru(II)-bpp-bpy complexes. Organic Photovoltaics vol. 4801,
125–135.
mla: Falaras, Polycarpos, et al. Dye-Sensitization of Titanium Dioxide Thin Films
by Ru(II)-Bpp-Bpy Complexes. Vol. 4801, SPIE, 2002, pp. 125–35, doi:10.1117/12.452446.
short: P. Falaras, K. Chryssou, T. Stergiopoulos, I. Arabatzis, G. Katsaros, V.
Catalano, R. Kurtaran, A. Hugot Le Goff, M. Bernard, in:, SPIE, 2002, pp. 125–135.
conference:
name: Organic Photovoltaics
date_created: 2018-12-11T11:53:45Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:53Z
day: '01'
doi: 10.1117/12.452446
extern: 1
intvolume: ' 4801'
month: '01'
page: 125 - 135
publication_status: published
publisher: SPIE
publist_id: '5385'
quality_controlled: 0
status: public
title: Dye-sensitization of titanium dioxide thin films by Ru(II)-bpp-bpy complexes
type: conference
volume: 4801
year: '2002'
...
---
_id: '1739'
abstract:
- lang: eng
text: Poly(ethylene oxide)/titania polymer electrolyte based photoelectrochemical
cells have been fabricated with Ru(dcbpy)2(NCS)2 complex as the sensitizer and
nanoporous TiO2 films as photoanodes. The introduction of the titania filler into
the poly(ethylene oxide) matrix reduces the crystallinity of the polymer and enhances
the mobility of the 1-/13 - redox couple, resulting in outstanding overall conversion
efficiency (4.2% under direct sunlight illumination) of the corresponding dye-sensitized
nanocrystalline TiO2 solar cell, one of the best efficiencies reported to date
for a solid-state device.
acknowledgement: 'Financial support from NCSR “Demokritos” and GSRT-Greece is greatly
acknowledged. '
author:
- first_name: Thomas
full_name: Stergiopoulos, Thomas
last_name: Stergiopoulos
- first_name: Iannis
full_name: Arabatzis, Iannis M
last_name: Arabatzis
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Polycarpos
full_name: Falaras, Polycarpos
last_name: Falaras
citation:
ama: Stergiopoulos T, Arabatzis I, Katsaros G, Falaras P. Binary Polyethylene Oxide/Titania
Solid-State Redox Electrolyte for Highly Efficient Nanocrystalline TiO2 Photoelectrochemical
Cells. Nano Letters. 2002;2(11):1259-1261. doi:10.1021/nl025798u
apa: Stergiopoulos, T., Arabatzis, I., Katsaros, G., & Falaras, P. (2002). Binary
Polyethylene Oxide/Titania Solid-State Redox Electrolyte for Highly Efficient
Nanocrystalline TiO2 Photoelectrochemical Cells. Nano Letters. American
Chemical Society. https://doi.org/10.1021/nl025798u
chicago: Stergiopoulos, Thomas, Iannis Arabatzis, Georgios Katsaros, and Polycarpos
Falaras. “Binary Polyethylene Oxide/Titania Solid-State Redox Electrolyte for
Highly Efficient Nanocrystalline TiO2 Photoelectrochemical Cells.” Nano Letters.
American Chemical Society, 2002. https://doi.org/10.1021/nl025798u.
ieee: T. Stergiopoulos, I. Arabatzis, G. Katsaros, and P. Falaras, “Binary Polyethylene
Oxide/Titania Solid-State Redox Electrolyte for Highly Efficient Nanocrystalline
TiO2 Photoelectrochemical Cells,” Nano Letters, vol. 2, no. 11. American
Chemical Society, pp. 1259–1261, 2002.
ista: Stergiopoulos T, Arabatzis I, Katsaros G, Falaras P. 2002. Binary Polyethylene
Oxide/Titania Solid-State Redox Electrolyte for Highly Efficient Nanocrystalline
TiO2 Photoelectrochemical Cells. Nano Letters. 2(11), 1259–1261.
mla: Stergiopoulos, Thomas, et al. “Binary Polyethylene Oxide/Titania Solid-State
Redox Electrolyte for Highly Efficient Nanocrystalline TiO2 Photoelectrochemical
Cells.” Nano Letters, vol. 2, no. 11, American Chemical Society, 2002,
pp. 1259–61, doi:10.1021/nl025798u.
short: T. Stergiopoulos, I. Arabatzis, G. Katsaros, P. Falaras, Nano Letters 2 (2002)
1259–1261.
date_created: 2018-12-11T11:53:45Z
date_published: 2002-11-01T00:00:00Z
date_updated: 2021-01-12T06:52:53Z
day: '01'
doi: 10.1021/nl025798u
extern: 1
intvolume: ' 2'
issue: '11'
month: '11'
page: 1259 - 1261
publication: Nano Letters
publication_status: published
publisher: American Chemical Society
publist_id: '5386'
quality_controlled: 0
status: public
title: Binary Polyethylene Oxide/Titania Solid-State Redox Electrolyte for Highly
Efficient Nanocrystalline TiO2 Photoelectrochemical Cells
type: journal_article
volume: 2
year: '2002'
...
---
_id: '2339'
alternative_title:
- Contemporary Mathematics
author:
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: 'Seiringer R. Symmetry breaking in a model of a rotating Bose gas. In: Weder
R, Exner P, Grébert B, eds. Vol 307. World Scientific Publishing; 2002:281-286.
doi:10.1090/conm/307'
apa: 'Seiringer, R. (2002). Symmetry breaking in a model of a rotating Bose gas.
In R. Weder, P. Exner, & B. Grébert (Eds.) (Vol. 307, pp. 281–286). Presented
at the QMath: Mathematical Results in Quantum Physics, World Scientific Publishing.
https://doi.org/10.1090/conm/307'
chicago: Seiringer, Robert. “Symmetry Breaking in a Model of a Rotating Bose Gas.”
edited by Richardo Weder, Pavel Exner, and Benoit Grébert, 307:281–86. World Scientific
Publishing, 2002. https://doi.org/10.1090/conm/307.
ieee: 'R. Seiringer, “Symmetry breaking in a model of a rotating Bose gas,” presented
at the QMath: Mathematical Results in Quantum Physics, 2002, vol. 307, pp. 281–286.'
ista: 'Seiringer R. 2002. Symmetry breaking in a model of a rotating Bose gas. QMath:
Mathematical Results in Quantum Physics, Contemporary Mathematics, vol. 307, 281–286.'
mla: Seiringer, Robert. Symmetry Breaking in a Model of a Rotating Bose Gas.
Edited by Richardo Weder et al., vol. 307, World Scientific Publishing, 2002,
pp. 281–86, doi:10.1090/conm/307.
short: R. Seiringer, in:, R. Weder, P. Exner, B. Grébert (Eds.), World Scientific
Publishing, 2002, pp. 281–286.
conference:
name: 'QMath: Mathematical Results in Quantum Physics'
date_created: 2018-12-11T11:57:05Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2021-01-12T06:56:53Z
day: '01'
doi: 10.1090/conm/307
editor:
- first_name: Richardo
full_name: Weder, Richardo
last_name: Weder
- first_name: Pavel
full_name: Exner, Pavel
last_name: Exner
- first_name: Benoit
full_name: Grébert, Benoit
last_name: Grébert
extern: 1
intvolume: ' 307'
month: '01'
page: 281 - 286
publication_status: published
publisher: World Scientific Publishing
publist_id: '4587'
quality_controlled: 0
status: public
title: Symmetry breaking in a model of a rotating Bose gas
type: conference
volume: 307
year: '2002'
...
---
_id: '2351'
abstract:
- lang: eng
text: We study the Gross-Pitaevskii functional for a rotating two-dimensional Bose
gas in a trap. We prove that there is a breaking of the rotational symmetry in
the ground state; more precisely, for any value of the angular velocity and for
large enough values of the interaction strength, the ground state of the functional
is not an eigenfunction of the angular momentum. This has interesting consequences
on the Bose gas with spin; in particular, the ground state energy depends non-trivially
on the number of spin components, and the different components do not have the
same wave function. For the special case of a harmonic trap potential, we give
explicit upper and lower bounds on the critical coupling constant for symmetry
breaking.
author:
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Seiringer R. Gross-Pitaevskii theory of the rotating Bose gas. Communications
in Mathematical Physics. 2002;229(3):491-509. doi:10.1007/s00220-002-0695-2
apa: Seiringer, R. (2002). Gross-Pitaevskii theory of the rotating Bose gas. Communications
in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-002-0695-2
chicago: Seiringer, Robert. “Gross-Pitaevskii Theory of the Rotating Bose Gas.”
Communications in Mathematical Physics. Springer, 2002. https://doi.org/10.1007/s00220-002-0695-2.
ieee: R. Seiringer, “Gross-Pitaevskii theory of the rotating Bose gas,” Communications
in Mathematical Physics, vol. 229, no. 3. Springer, pp. 491–509, 2002.
ista: Seiringer R. 2002. Gross-Pitaevskii theory of the rotating Bose gas. Communications
in Mathematical Physics. 229(3), 491–509.
mla: Seiringer, Robert. “Gross-Pitaevskii Theory of the Rotating Bose Gas.” Communications
in Mathematical Physics, vol. 229, no. 3, Springer, 2002, pp. 491–509, doi:10.1007/s00220-002-0695-2.
short: R. Seiringer, Communications in Mathematical Physics 229 (2002) 491–509.
date_created: 2018-12-11T11:57:09Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2021-01-12T06:56:57Z
day: '01'
doi: 10.1007/s00220-002-0695-2
extern: 1
intvolume: ' 229'
issue: '3'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0110010
month: '09'
oa: 1
page: 491 - 509
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4575'
quality_controlled: 0
status: public
title: Gross-Pitaevskii theory of the rotating Bose gas
type: journal_article
volume: 229
year: '2002'
...
---
_id: '2349'
abstract:
- lang: eng
text: The Bose-Einstein condensation (BEC) of the ground state of bosonic atoms
in a trap was discussed. The BEC was proved for bosons with two-body repulsive
interaction potentials in the dilute limit, starting from the basic Schrodinger
equation. The BEC was 100% into the state which minimized the Gross-Pitaevskii
energy functional. The analysis also included rigorous proof of BEC in a physically
realistic, continuum model.
author:
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lieb É, Seiringer R. Proof of Bose-Einstein condensation for dilute trapped
gases. Physical Review Letters. 2002;88(17):1704091-1704094. doi:10.1103/PhysRevLett.88.170409
apa: Lieb, É., & Seiringer, R. (2002). Proof of Bose-Einstein condensation for
dilute trapped gases. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.88.170409
chicago: Lieb, Élliott, and Robert Seiringer. “Proof of Bose-Einstein Condensation
for Dilute Trapped Gases.” Physical Review Letters. American Physical Society,
2002. https://doi.org/10.1103/PhysRevLett.88.170409.
ieee: É. Lieb and R. Seiringer, “Proof of Bose-Einstein condensation for dilute
trapped gases,” Physical Review Letters, vol. 88, no. 17. American Physical
Society, pp. 1704091–1704094, 2002.
ista: Lieb É, Seiringer R. 2002. Proof of Bose-Einstein condensation for dilute
trapped gases. Physical Review Letters. 88(17), 1704091–1704094.
mla: Lieb, Élliott, and Robert Seiringer. “Proof of Bose-Einstein Condensation for
Dilute Trapped Gases.” Physical Review Letters, vol. 88, no. 17, American
Physical Society, 2002, pp. 1704091–94, doi:10.1103/PhysRevLett.88.170409.
short: É. Lieb, R. Seiringer, Physical Review Letters 88 (2002) 1704091–1704094.
date_created: 2018-12-11T11:57:08Z
date_published: 2002-04-29T00:00:00Z
date_updated: 2021-01-12T06:56:56Z
day: '29'
doi: 10.1103/PhysRevLett.88.170409
extern: 1
intvolume: ' 88'
issue: '17'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0112032
month: '04'
oa: 1
page: 1704091 - 1704094
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '4577'
quality_controlled: 0
status: public
title: Proof of Bose-Einstein condensation for dilute trapped gases
type: journal_article
volume: 88
year: '2002'
...
---
_id: '2352'
abstract:
- lang: eng
text: We present a generalization of the Fefferman-de la Llave decomposition of
the Coulomb potential to quite arbitrary radial functions V on ℝn going to zero
at infinity. This generalized decomposition can be used to extend previous results
on N-body quantum systems with Coulomb interaction to a more general class of
interactions. As an example of such an application, we derive the high density
asymptotics of the ground state energy of jellium with Yukawa interaction in the
thermodynamic limit, using a correlation estimate by Graf and Solovej.
author:
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Hainzl C, Seiringer R. General decomposition of radial functions on ℝn and
applications to N-body quantum systems. Letters in Mathematical Physics.
2002;61(1):75-84. doi:10.1023/A:1020204818938
apa: Hainzl, C., & Seiringer, R. (2002). General decomposition of radial functions
on ℝn and applications to N-body quantum systems. Letters in Mathematical Physics.
Springer. https://doi.org/10.1023/A:1020204818938
chicago: Hainzl, Christian, and Robert Seiringer. “General Decomposition of Radial
Functions on ℝn and Applications to N-Body Quantum Systems.” Letters in Mathematical
Physics. Springer, 2002. https://doi.org/10.1023/A:1020204818938.
ieee: C. Hainzl and R. Seiringer, “General decomposition of radial functions on
ℝn and applications to N-body quantum systems,” Letters in Mathematical Physics,
vol. 61, no. 1. Springer, pp. 75–84, 2002.
ista: Hainzl C, Seiringer R. 2002. General decomposition of radial functions on
ℝn and applications to N-body quantum systems. Letters in Mathematical Physics.
61(1), 75–84.
mla: Hainzl, Christian, and Robert Seiringer. “General Decomposition of Radial Functions
on ℝn and Applications to N-Body Quantum Systems.” Letters in Mathematical
Physics, vol. 61, no. 1, Springer, 2002, pp. 75–84, doi:10.1023/A:1020204818938.
short: C. Hainzl, R. Seiringer, Letters in Mathematical Physics 61 (2002) 75–84.
date_created: 2018-12-11T11:57:09Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2021-01-12T06:56:58Z
day: '01'
doi: 10.1023/A:1020204818938
extern: 1
intvolume: ' 61'
issue: '1'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0107011
month: '07'
oa: 1
page: 75 - 84
publication: Letters in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4576'
quality_controlled: 0
status: public
title: General decomposition of radial functions on ℝn and applications to N-body
quantum systems
type: journal_article
volume: 61
year: '2002'
...
---
_id: '2617'
abstract:
- lang: eng
text: Synapses exhibit different short-term plasticity patterns and this behaviour
influences information processing in neuronal networks. We tested how the short-term
plasticity of excitatory postsynaptic currents (EPSCs) depends on the postsynaptic
cell type, identified by axonal arborizations and molecular markers in the hippocampal
CA1 area. Three distinct types of short-term synaptic behaviour (facilitating,
depressing and combined facilitating-depressing) were defined by fitting a dynamic
neurotransmission model to the data. Approximately 75 % of the oriens-lacunosum-moleculare
(O-LM) interneurones received facilitating EPSCs, but in three of 12 O-LM cells
EPSCs also showed significant depression. Over 90 % of the O-LM cells were immunopositive
for somatostatin and mGluR1α and all tested cells were decorated by strongly mGluR7a
positive axon terminals. Responses in eight of 12 basket cells were described
well with a model involving only depression, but the other cells displayed combined
facilitating-depressing EPSCs. No apparent difference was found between the plasticity
of EPSCs in cholecystokinin- or parvalbumin-containing basket cells. In oriens-bistratified
cells (O-Bi), two of nine cells showed facilitating EPSCs, another two depressing,
and the remaining five cells combined facilitating-depressing EPSCs. Seven of
10 cells tested for somatostatin were immunopositive, but mGluR1α was detectable
only in two of 11 tested cells. Furthermore, most O-Bi cells projected to the
CA3 area and the subiculum, as well as outside the hippocampal formation. Postsynaptic
responses to action potentials recorded in vivo from a CA1 place cell were modelled,
and revealed great differences between and within cell types. Our results demonstrate
that the short-term plasticity of EPSCs is cell type dependent, but with significant
heterogeneity within all three interneurone populations.
author:
- first_name: Attila
full_name: Losonczy, Attila
last_name: Losonczy
- first_name: Limei
full_name: Zhang, Limei
last_name: Zhang
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
- first_name: Zoltán
full_name: Nusser, Zoltán
last_name: Nusser
citation:
ama: Losonczy A, Zhang L, Shigemoto R, Somogyi P, Nusser Z. Cell type dependence
and variability in the short-term plasticity of EPSCs in identified mouse hippocampal
interneurones. Journal of Physiology. 2002;542(1):193-210. doi:10.1113/jphysiol.2002.020024
apa: Losonczy, A., Zhang, L., Shigemoto, R., Somogyi, P., & Nusser, Z. (2002).
Cell type dependence and variability in the short-term plasticity of EPSCs in
identified mouse hippocampal interneurones. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2002.020024
chicago: Losonczy, Attila, Limei Zhang, Ryuichi Shigemoto, Péter Somogyi, and Zoltán
Nusser. “Cell Type Dependence and Variability in the Short-Term Plasticity of
EPSCs in Identified Mouse Hippocampal Interneurones.” Journal of Physiology.
Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2002.020024.
ieee: A. Losonczy, L. Zhang, R. Shigemoto, P. Somogyi, and Z. Nusser, “Cell type
dependence and variability in the short-term plasticity of EPSCs in identified
mouse hippocampal interneurones,” Journal of Physiology, vol. 542, no.
1. Wiley-Blackwell, pp. 193–210, 2002.
ista: Losonczy A, Zhang L, Shigemoto R, Somogyi P, Nusser Z. 2002. Cell type dependence
and variability in the short-term plasticity of EPSCs in identified mouse hippocampal
interneurones. Journal of Physiology. 542(1), 193–210.
mla: Losonczy, Attila, et al. “Cell Type Dependence and Variability in the Short-Term
Plasticity of EPSCs in Identified Mouse Hippocampal Interneurones.” Journal
of Physiology, vol. 542, no. 1, Wiley-Blackwell, 2002, pp. 193–210, doi:10.1113/jphysiol.2002.020024.
short: A. Losonczy, L. Zhang, R. Shigemoto, P. Somogyi, Z. Nusser, Journal of Physiology
542 (2002) 193–210.
date_created: 2018-12-11T11:58:42Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2021-01-12T06:58:36Z
day: '01'
doi: 10.1113/jphysiol.2002.020024
extern: 1
intvolume: ' 542'
issue: '1'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290398/
month: '07'
oa: 1
page: 193 - 210
publication: Journal of Physiology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4281'
quality_controlled: 0
status: public
title: Cell type dependence and variability in the short-term plasticity of EPSCs
in identified mouse hippocampal interneurones
type: journal_article
volume: 542
year: '2002'
...
---
_id: '2708'
alternative_title:
- Contemporary Mathematics
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: 'Erdös L. Two dimensional Pauli operator via scalar potential. In: Vol 307.
World Scientific Publishing; 2002:129-133. doi:10.1090/conm/307'
apa: 'Erdös, L. (2002). Two dimensional Pauli operator via scalar potential (Vol.
307, pp. 129–133). Presented at the QMath: Mathematical Results in Quantum Physics,
World Scientific Publishing. https://doi.org/10.1090/conm/307'
chicago: Erdös, László. “Two Dimensional Pauli Operator via Scalar Potential,” 307:129–33.
World Scientific Publishing, 2002. https://doi.org/10.1090/conm/307.
ieee: 'L. Erdös, “Two dimensional Pauli operator via scalar potential,” presented
at the QMath: Mathematical Results in Quantum Physics, 2002, vol. 307, pp. 129–133.'
ista: 'Erdös L. 2002. Two dimensional Pauli operator via scalar potential. QMath:
Mathematical Results in Quantum Physics, Contemporary Mathematics, vol. 307, 129–133.'
mla: Erdös, László. Two Dimensional Pauli Operator via Scalar Potential.
Vol. 307, World Scientific Publishing, 2002, pp. 129–33, doi:10.1090/conm/307.
short: L. Erdös, in:, World Scientific Publishing, 2002, pp. 129–133.
conference:
name: 'QMath: Mathematical Results in Quantum Physics'
date_created: 2018-12-11T11:59:11Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2021-01-12T06:59:11Z
day: '01'
doi: 10.1090/conm/307
extern: 1
intvolume: ' 307'
month: '01'
page: 129 - 133
publication_status: published
publisher: World Scientific Publishing
publist_id: '4188'
quality_controlled: 0
status: public
title: Two dimensional Pauli operator via scalar potential
type: conference
volume: 307
year: '2002'
...
---
_id: '2991'
abstract:
- lang: eng
text: Polar auxin transport controls multiple aspects of plant development including
differential growth, embryo and root patterning and vascular tissue differentiation.
Identification of proteins involved in this process and availability of new tools
enabling `visualization' of auxin and auxin routes in planta largely contributed
to the significant progress that has recently been made. New data support classical
concepts, but several recent findings are likely to challenge our view on the
mechanism of auxin transport. The aim of this review is to provide a comprehensive
overview of the polar auxin transport field. It starts with classical models resulting
from physiological studies, describes the genetic contributions and discusses
the molecular basis of auxin influx and efflux. Finally, selected questions are
presented in the context of developmental biology, integrating available data
from different fields.
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
citation:
ama: Friml J, Palme K. Polar auxin transport - Old questions and new concepts? Plant
Molecular Biology. 2002;49(3-4):273-284. doi:10.1023/A:1015248926412
apa: Friml, J., & Palme, K. (2002). Polar auxin transport - Old questions and
new concepts? Plant Molecular Biology. Springer. https://doi.org/10.1023/A:1015248926412
chicago: Friml, Jiří, and Klaus Palme. “Polar Auxin Transport - Old Questions and
New Concepts?” Plant Molecular Biology. Springer, 2002. https://doi.org/10.1023/A:1015248926412.
ieee: J. Friml and K. Palme, “Polar auxin transport - Old questions and new concepts?,”
Plant Molecular Biology, vol. 49, no. 3–4. Springer, pp. 273–284, 2002.
ista: Friml J, Palme K. 2002. Polar auxin transport - Old questions and new concepts?
Plant Molecular Biology. 49(3–4), 273–284.
mla: Friml, Jiří, and Klaus Palme. “Polar Auxin Transport - Old Questions and New
Concepts?” Plant Molecular Biology, vol. 49, no. 3–4, Springer, 2002, pp.
273–84, doi:10.1023/A:1015248926412.
short: J. Friml, K. Palme, Plant Molecular Biology 49 (2002) 273–284.
date_created: 2018-12-11T12:00:44Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2021-01-12T07:40:17Z
day: '01'
doi: 10.1023/A:1015248926412
extern: '1'
intvolume: ' 49'
issue: 3-4
language:
- iso: eng
month: '06'
oa_version: None
page: 273 - 284
publication: Plant Molecular Biology
publication_status: published
publisher: Springer
publist_id: '3712'
quality_controlled: '1'
status: public
title: Polar auxin transport - Old questions and new concepts?
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 49
year: '2002'
...
---
_id: '3508'
abstract:
- lang: eng
text: A method of automatic conversion of a physical object into a three-dimensional
digital model. The method acquires a set of measured data points on the surface
of a physical model. From the measured data points, the method reconstructs a
digital model of the physical object using a Delaunay complex of the points, a
flow strcuture of the simplicies in the Delaunay complex and retracting the Delaunay
complex into a digital model of the physical object using the flow structure.
The method then outputs the digital model of the physical object.
applicant:
- Raindrop Geomagic, Inc.
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Ping
full_name: Fu, Ping
last_name: Fu
citation:
ama: Edelsbrunner H, Fu P. Methods of generating three-dimensional digital models
of objects by wrapping point cloud data points. 2002.
apa: Edelsbrunner, H., & Fu, P. (2002). Methods of generating three-dimensional
digital models of objects by wrapping point cloud data points.
chicago: Edelsbrunner, Herbert, and Ping Fu. “Methods of Generating Three-Dimensional
Digital Models of Objects by Wrapping Point Cloud Data Points,” 2002.
ieee: H. Edelsbrunner and P. Fu, “Methods of generating three-dimensional digital
models of objects by wrapping point cloud data points.” 2002.
ista: Edelsbrunner H, Fu P. 2002. Methods of generating three-dimensional digital
models of objects by wrapping point cloud data points.
mla: Edelsbrunner, Herbert, and Ping Fu. Methods of Generating Three-Dimensional
Digital Models of Objects by Wrapping Point Cloud Data Points. 2002.
short: H. Edelsbrunner, P. Fu, (2002).
date_created: 2018-12-11T12:03:42Z
date_published: 2002-04-23T00:00:00Z
date_updated: 2022-01-05T14:09:36Z
day: '23'
extern: '1'
ipc: G16Z99/00 ; G06K9/28 ; G06T17/10 ; G06T17/20
ipn: US6377865B1
main_file_link:
- open_access: '1'
url: https://patents.google.com/patent/US6377865B1
month: '04'
oa: 1
oa_version: Published Version
publication_date: 2002-04-23
publist_id: '2879'
status: public
title: Methods of generating three-dimensional digital models of objects by wrapping
point cloud data points
type: patent
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2002'
...
---
_id: '3448'
author:
- first_name: Sanhita
full_name: Mallick, Sanhita
last_name: Mallick
- first_name: Krishnendu
full_name: Krishnendu Chatterjee
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Arif
full_name: Merchant, Arif N
last_name: Merchant
- first_name: Pallab
full_name: Dasgupta, Pallab
last_name: Dasgupta
citation:
ama: 'Mallick S, Chatterjee K, Merchant A, Dasgupta P. Implementation of shape grammar
for plan analysis. In: Elsevier; 2002.'
apa: 'Mallick, S., Chatterjee, K., Merchant, A., & Dasgupta, P. (2002). Implementation
of shape grammar for plan analysis. Presented at the IT-Built: Information Technology
For Built Environment, Elsevier.'
chicago: Mallick, Sanhita, Krishnendu Chatterjee, Arif Merchant, and Pallab Dasgupta.
“Implementation of Shape Grammar for Plan Analysis.” Elsevier, 2002.
ieee: 'S. Mallick, K. Chatterjee, A. Merchant, and P. Dasgupta, “Implementation
of shape grammar for plan analysis,” presented at the IT-Built: Information Technology
For Built Environment, 2002.'
ista: 'Mallick S, Chatterjee K, Merchant A, Dasgupta P. 2002. Implementation of
shape grammar for plan analysis. IT-Built: Information Technology For Built Environment.'
mla: Mallick, Sanhita, et al. Implementation of Shape Grammar for Plan Analysis.
Elsevier, 2002.
short: S. Mallick, K. Chatterjee, A. Merchant, P. Dasgupta, in:, Elsevier, 2002.
conference:
name: 'IT-Built: Information Technology For Built Environment'
date_created: 2018-12-11T12:03:23Z
date_published: 2002-01-15T00:00:00Z
date_updated: 2021-01-12T07:43:31Z
day: '15'
extern: 1
month: '01'
publication_status: published
publisher: Elsevier
publist_id: '2939'
quality_controlled: 0
status: public
title: Implementation of shape grammar for plan analysis
type: conference
year: '2002'
...
---
_id: '4414'
abstract:
- lang: eng
text: "This dissertation investigates game-theoretic approaches to the algorithmic
analysis of concurrent, reactive systems. A concurrent system comprises a number
of components working concurrently; a reactive system maintains an ongoing interaction
with its environment. Traditional approaches to the formal analysis of concurrent
reactive systems usually view the system as an unstructured state-transition graphs;
instead, we view them as collections of interacting components, where each one
is an open system which accepts inputs from the other components. The interactions
among the components are naturally modeled as games.\r\n\r\nAdopting this game-theoretic
view, we study three related problems pertaining to the verification and synthesis
of systems. Firstly, we propose two novel game-theoretic techniques for the model-checking
of concurrent reactive systems, and improve the performance of model-checking.
The first technique discovers an error as soon as it cannot be prevented, which
can be long before it actually occurs. This technique is based on the key observation
that "unpreventability" is a local property to a module: an error is
unpreventable in a module state if no environment can prevent it. The second technique
attempts to decompose a model-checking proof into smaller proof obligations by
constructing abstract modules automatically, using reachability and "unpreventability"
information about the concrete modules. Three increasingly powerful proof decomposition
rules are proposed and we show that in practice, the resulting abstract modules
are often significantly smaller than the concrete modules and can drastically
reduce the space and time requirements for verification. Both techniques fall
into the category of compositional reasoning.\r\n\r\nSecondly, we investigate
the composition and control of synchronous systems. An essential property of synchronous
systems for compositional reasoning is non-blocking. In the composition of synchronous
systems, however, due to circular causal dependency of input and output signals,
non-blocking is not always guaranteed. Blocking compositions of systems can be
ruled out semantically, by insisting on the existence of certain fixed points,
or syntactically, by equipping systems with types, which make the dependencies
between input and output signals transparent. We characterize various typing mechanisms
in game-theoretic terms, and study their effects on the controller synthesis problem.
We show that our typing systems are general enough to capture interesting real-life
synchronous systems such as all delay-insensitive digital circuits. We then study
their corresponding single-step control problems --a restricted form of controller
synthesis problem whose solutions can be iterated in appropriate manners to solve
all LTL controller synthesis problems. We also consider versions of the controller
synthesis problem in which the type of the controller is given. We show that the
solution of these fixed-type control problems requires the evaluation of partially
ordered (Henkin) quantifiers on boolean formulas, and is therefore harder (nondeterministic
exponential time) than more traditional control questions.\r\n\r\nThirdly, we
study the synthesis of a class of open systems, namely, uninitialized state machines.
The sequential synthesis problem, which is closely related to Church's solvability
problem, asks, given a specification in the form of a binary relation between
input and output streams, for the construction of a finite-state stream transducer
that converts inputs to appropriate outputs. For efficiency reasons, practical
sequential hardware is often designed to operate without prior initialization.
Such hardware designs can be modeled by uninitialized state machines, which are
required to satisfy their specification if started from any state. We solve the
sequential synthesis problem for uninitialized systems, that is, we construct
uninitialized finite-state stream transducers. We consider specifications given
by LTL formulas, deterministic, nondeterministic, universal, and alternating Buechi
automata. We solve this uninitialized synthesis problem by reducing it to the
well-understood initialized synthesis problem. While our solution is straightforward,
it leads, for some specification formalisms, to upper bounds that are exponentially
worse than the complexity of the corresponding initialized problems. However,
we prove lower bounds to show that our simple solutions are optimal for all considered
specification formalisms. The lower bound proofs require nontrivial generic reductions."
article_processing_charge: No
author:
- first_name: Freddy
full_name: Mang, Freddy
last_name: Mang
citation:
ama: Mang F. Games in open systems verification and synthesis. 2002:1-116.
apa: Mang, F. (2002). Games in open systems verification and synthesis. University
of California, Berkeley.
chicago: Mang, Freddy. “Games in Open Systems Verification and Synthesis.” University
of California, Berkeley, 2002.
ieee: F. Mang, “Games in open systems verification and synthesis,” University of
California, Berkeley, 2002.
ista: Mang F. 2002. Games in open systems verification and synthesis. University
of California, Berkeley.
mla: Mang, Freddy. Games in Open Systems Verification and Synthesis. University
of California, Berkeley, 2002, pp. 1–116.
short: F. Mang, Games in Open Systems Verification and Synthesis, University of
California, Berkeley, 2002.
date_created: 2018-12-11T12:08:44Z
date_published: 2002-05-01T00:00:00Z
date_updated: 2021-01-12T07:56:48Z
day: '01'
extern: '1'
language:
- iso: eng
month: '05'
oa_version: None
page: 1 - 116
publication_status: published
publisher: University of California, Berkeley
publist_id: '315'
status: public
supervisor:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000-0002-2985-7724
title: Games in open systems verification and synthesis
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2002'
...
---
_id: '6158'
abstract:
- lang: eng
text: Wild isolates of Caenorhabditis elegans can feed either alone or in groups1,2.
This natural variation in behaviour is associated with a single residue difference
in NPR-1, a predicted G-protein-coupled neuropeptide receptor related to Neuropeptide
Y receptors2. Here we show that the NPR-1 isoform associated with solitary feeding
acts in neurons exposed to the body fluid to inhibit social feeding. Furthermore,
suppressing the activity of these neurons, called AQR, PQR and URX, using an activated
K+ channel, inhibits social feeding. NPR-1 activity in AQR, PQR and URX neurons
seems to suppress social feeding by antagonizing signalling through a cyclic GMP-gated
ion channel encoded by tax-2 and tax-4. We show that mutations in tax-2 or tax-4
disrupt social feeding, and that tax-4 is required in several neurons for social
feeding, including one or more of AQR, PQR and URX. The AQR, PQR and URX neurons
are unusual in C. elegans because they are directly exposed to the pseudocoelomic
body fluid3. Our data suggest a model in which these neurons integrate antagonistic
signals to control the choice between social and solitary feeding behaviour.
author:
- first_name: Juliet C.
full_name: Coates, Juliet C.
last_name: Coates
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Coates JC, de Bono M. Antagonistic pathways in neurons exposed to body fluid
regulate social feeding in Caenorhabditis elegans. Nature. 2002;419(6910):925-929.
doi:10.1038/nature01170
apa: Coates, J. C., & de Bono, M. (2002). Antagonistic pathways in neurons exposed
to body fluid regulate social feeding in Caenorhabditis elegans. Nature.
Springer Nature. https://doi.org/10.1038/nature01170
chicago: Coates, Juliet C., and Mario de Bono. “Antagonistic Pathways in Neurons
Exposed to Body Fluid Regulate Social Feeding in Caenorhabditis Elegans.” Nature.
Springer Nature, 2002. https://doi.org/10.1038/nature01170.
ieee: J. C. Coates and M. de Bono, “Antagonistic pathways in neurons exposed to
body fluid regulate social feeding in Caenorhabditis elegans,” Nature,
vol. 419, no. 6910. Springer Nature, pp. 925–929, 2002.
ista: Coates JC, de Bono M. 2002. Antagonistic pathways in neurons exposed to body
fluid regulate social feeding in Caenorhabditis elegans. Nature. 419(6910), 925–929.
mla: Coates, Juliet C., and Mario de Bono. “Antagonistic Pathways in Neurons Exposed
to Body Fluid Regulate Social Feeding in Caenorhabditis Elegans.” Nature,
vol. 419, no. 6910, Springer Nature, 2002, pp. 925–29, doi:10.1038/nature01170.
short: J.C. Coates, M. de Bono, Nature 419 (2002) 925–929.
date_created: 2019-03-21T10:09:20Z
date_published: 2002-10-31T00:00:00Z
date_updated: 2021-01-12T08:06:26Z
day: '31'
doi: 10.1038/nature01170
extern: '1'
external_id:
pmid:
- '12410311'
intvolume: ' 419'
issue: '6910'
language:
- iso: eng
month: '10'
oa_version: None
page: 925-929
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Antagonistic pathways in neurons exposed to body fluid regulate social feeding
in Caenorhabditis elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 419
year: '2002'
...
---
_id: '6159'
abstract:
- lang: eng
text: 'Natural Caenorhabditis elegans isolates exhibit either social or solitary
feeding on bacteria. We show here that social feeding is induced by nociceptive
neurons that detect adverse or stressful conditions. Ablation of the nociceptive
neurons ASH and ADL transforms social animals into solitary feeders. Social feeding
is probably due to the sensation of noxious chemicals by ASH and ADL neurons;
it requires the genes ocr-2 and osm-9, which encode TRP-related transduction channels,
and odr-4 and odr-8, which are required to localize sensory chemoreceptors to
cilia. Other sensory neurons may suppress social feeding, as social feeding in
ocr-2 and odr-4 mutants is restored by mutations in osm-3, a gene required for
the development of 26 ciliated sensory neurons. Our data suggest a model for regulation
of social feeding by opposing sensory inputs: aversive inputs to nociceptive neurons
promote social feeding, whereas antagonistic inputs from neurons that express
osm-3 inhibit aggregation.'
author:
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
- first_name: David M.
full_name: Tobin, David M.
last_name: Tobin
- first_name: M. Wayne
full_name: Davis, M. Wayne
last_name: Davis
- first_name: Leon
full_name: Avery, Leon
last_name: Avery
- first_name: Cornelia I.
full_name: Bargmann, Cornelia I.
last_name: Bargmann
citation:
ama: de Bono M, Tobin DM, Davis MW, Avery L, Bargmann CI. Social feeding in Caenorhabditis
elegans is induced by neurons that detect aversive stimuli. Nature. 2002;419(6910):899-903.
doi:10.1038/nature01169
apa: de Bono, M., Tobin, D. M., Davis, M. W., Avery, L., & Bargmann, C. I. (2002).
Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive
stimuli. Nature. Springer Nature. https://doi.org/10.1038/nature01169
chicago: Bono, Mario de, David M. Tobin, M. Wayne Davis, Leon Avery, and Cornelia
I. Bargmann. “Social Feeding in Caenorhabditis Elegans Is Induced by Neurons That
Detect Aversive Stimuli.” Nature. Springer Nature, 2002. https://doi.org/10.1038/nature01169.
ieee: M. de Bono, D. M. Tobin, M. W. Davis, L. Avery, and C. I. Bargmann, “Social
feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli,”
Nature, vol. 419, no. 6910. Springer Nature, pp. 899–903, 2002.
ista: de Bono M, Tobin DM, Davis MW, Avery L, Bargmann CI. 2002. Social feeding
in Caenorhabditis elegans is induced by neurons that detect aversive stimuli.
Nature. 419(6910), 899–903.
mla: de Bono, Mario, et al. “Social Feeding in Caenorhabditis Elegans Is Induced
by Neurons That Detect Aversive Stimuli.” Nature, vol. 419, no. 6910, Springer
Nature, 2002, pp. 899–903, doi:10.1038/nature01169.
short: M. de Bono, D.M. Tobin, M.W. Davis, L. Avery, C.I. Bargmann, Nature 419 (2002)
899–903.
date_created: 2019-03-21T10:27:04Z
date_published: 2002-10-31T00:00:00Z
date_updated: 2021-01-12T08:06:27Z
day: '31'
doi: 10.1038/nature01169
extern: '1'
external_id:
pmid:
- '12410303'
intvolume: ' 419'
issue: '6910'
language:
- iso: eng
month: '10'
oa_version: None
page: 899-903
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Social feeding in Caenorhabditis elegans is induced by neurons that detect
aversive stimuli
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 419
year: '2002'
...
---
_id: '4631'
abstract:
- lang: eng
text: We present a theory of timed interfaces, which is capable of specifying both
the timing of the inputs a component expects from the environment, and the timing
of the outputs it can produce. Two timed interfaces are compatible if there is
a way to use them together such that their timing expectations are met. Our theory
provides algorithms for checking the compatibility between two interfaces and
for deriving the composite interface; the theory can thus be viewed as a type
system for real-time interaction. Technically, a timed interface is encoded as
a timed game between two players, representing the inputs and outputs of the component.
The algorithms for compatibility checking and interface composition are thus derived
from algorithms for solving timed games.
acknowledgement: This research was supported in part by the NSF CAREER award CCR-0132780,
the NSF grant CCR-9988172 the AFOSR MURI grant F49620-00-1-0327, the DARPA PCES
grant F33615-00-C-1693, the MARCO GSRC grant 98-DT-660, and the ONR grant N00014-02-1-0671.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Mariëlle
full_name: Stoelinga, Mariëlle
last_name: Stoelinga
citation:
ama: 'De Alfaro L, Henzinger TA, Stoelinga M. Timed interfaces. In: Proceedings
of the 2nd International Conference on Embedded Software. Vol 2491. ACM; 2002:108-122.
doi:10.1007/3-540-45828-X_9'
apa: 'De Alfaro, L., Henzinger, T. A., & Stoelinga, M. (2002). Timed interfaces.
In Proceedings of the 2nd International Conference on Embedded Software
(Vol. 2491, pp. 108–122). Grenoble, France: ACM. https://doi.org/10.1007/3-540-45828-X_9'
chicago: De Alfaro, Luca, Thomas A Henzinger, and Mariëlle Stoelinga. “Timed Interfaces.”
In Proceedings of the 2nd International Conference on Embedded Software,
2491:108–22. ACM, 2002. https://doi.org/10.1007/3-540-45828-X_9.
ieee: L. De Alfaro, T. A. Henzinger, and M. Stoelinga, “Timed interfaces,” in Proceedings
of the 2nd International Conference on Embedded Software, Grenoble, France,
2002, vol. 2491, pp. 108–122.
ista: 'De Alfaro L, Henzinger TA, Stoelinga M. 2002. Timed interfaces. Proceedings
of the 2nd International Conference on Embedded Software. EMSOFT: Embedded Software
, LNCS, vol. 2491, 108–122.'
mla: De Alfaro, Luca, et al. “Timed Interfaces.” Proceedings of the 2nd International
Conference on Embedded Software, vol. 2491, ACM, 2002, pp. 108–22, doi:10.1007/3-540-45828-X_9.
short: L. De Alfaro, T.A. Henzinger, M. Stoelinga, in:, Proceedings of the 2nd International
Conference on Embedded Software, ACM, 2002, pp. 108–122.
conference:
end_date: 2002-10-09
location: Grenoble, France
name: 'EMSOFT: Embedded Software '
start_date: 2002-10-07
date_created: 2018-12-11T12:09:51Z
date_published: 2002-10-24T00:00:00Z
date_updated: 2023-06-02T10:00:32Z
day: '24'
doi: 10.1007/3-540-45828-X_9
extern: '1'
intvolume: ' 2491'
language:
- iso: eng
month: '10'
oa_version: None
page: 108 - 122
publication: Proceedings of the 2nd International Conference on Embedded Software
publication_identifier:
isbn:
- '9783540443070'
publication_status: published
publisher: ACM
publist_id: '76'
quality_controlled: '1'
status: public
title: Timed interfaces
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2491
year: '2002'
...
---
_id: '4562'
abstract:
- lang: eng
text: We present interface models that describe both the input assumptions of a
component, and its output behavior. By enabling us to check that the input assumptions
of a component are met in a design, interface models provide a compatibility check
for component-based design. When refining a design into an implementation, interface
models require that the output behavior of a component satisfies the design specification
only when the input assumptions of the specification are satisfied, yielding greater
flexibility in the choice of implementations. Technically, our interface models
are games between two players, Input and Output; the duality of the players accounts
for the dual roles of inputs and outputs in composition and refinement. We present
two interface models in detail, one for a simple synchronous form of interaction
between components typical in hardware, and the other for more complex synchronous
interactions on bidirectional connections. As an example, we specify the interface
of a bidirectional bus, with the input assumption that at any time at most one
component has write access to the bus. For these interface models, we present
algorithms for compatibility and refinement checking, and we describe efficient
symbolic implementations.
acknowledgement: This research was supported in part by the AFOSR grant F49620-00-1-0327,
the DARPA grant F33615-00-C-1693, the MARCO grant 98-DT-660, the NSF grant CCR-9988172,
the SRC grant 99-TJ-683.003, and the NSF CAREER award CCR-0132780.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Arindam
full_name: Chakrabarti, Arindam
last_name: Chakrabarti
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Freddy
full_name: Mang, Freddy
last_name: Mang
citation:
ama: 'Chakrabarti A, De Alfaro L, Henzinger TA, Mang F. Synchronous and bidirectional
component interfaces. In: Proceedings of the 14th International Conference
on Computer Aided Verification. Vol 2404. Springer; 2002:414-427. doi:10.1007/3-540-45657-0_34'
apa: 'Chakrabarti, A., De Alfaro, L., Henzinger, T. A., & Mang, F. (2002). Synchronous
and bidirectional component interfaces. In Proceedings of the 14th International
Conference on Computer Aided Verification (Vol. 2404, pp. 414–427). Copenhagen,
Denmark: Springer. https://doi.org/10.1007/3-540-45657-0_34'
chicago: Chakrabarti, Arindam, Luca De Alfaro, Thomas A Henzinger, and Freddy Mang.
“Synchronous and Bidirectional Component Interfaces.” In Proceedings of the
14th International Conference on Computer Aided Verification, 2404:414–27.
Springer, 2002. https://doi.org/10.1007/3-540-45657-0_34.
ieee: A. Chakrabarti, L. De Alfaro, T. A. Henzinger, and F. Mang, “Synchronous and
bidirectional component interfaces,” in Proceedings of the 14th International
Conference on Computer Aided Verification, Copenhagen, Denmark, 2002, vol.
2404, pp. 414–427.
ista: 'Chakrabarti A, De Alfaro L, Henzinger TA, Mang F. 2002. Synchronous and bidirectional
component interfaces. Proceedings of the 14th International Conference on Computer
Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 2404, 414–427.'
mla: Chakrabarti, Arindam, et al. “Synchronous and Bidirectional Component Interfaces.”
Proceedings of the 14th International Conference on Computer Aided Verification,
vol. 2404, Springer, 2002, pp. 414–27, doi:10.1007/3-540-45657-0_34.
short: A. Chakrabarti, L. De Alfaro, T.A. Henzinger, F. Mang, in:, Proceedings of
the 14th International Conference on Computer Aided Verification, Springer, 2002,
pp. 414–427.
conference:
end_date: 2002-07-31
location: Copenhagen, Denmark
name: 'CAV: Computer Aided Verification'
start_date: 2002-07-27
date_created: 2018-12-11T12:09:29Z
date_published: 2002-06-19T00:00:00Z
date_updated: 2023-06-02T12:01:22Z
day: '19'
doi: 10.1007/3-540-45657-0_34
extern: '1'
intvolume: ' 2404'
language:
- iso: eng
month: '06'
oa_version: None
page: 414 - 427
publication: Proceedings of the 14th International Conference on Computer Aided Verification
publication_identifier:
isbn:
- '9783540439974'
publication_status: published
publisher: Springer
publist_id: '146'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synchronous and bidirectional component interfaces
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2404
year: '2002'
...
---
_id: '4565'
abstract:
- lang: eng
text: "In the literature, we find several formulations of the control\r\nproblem
for timed and hybrid systems. We argue that formulations where\r\na controller
can cause an action at any point in dense (rational or real)\r\ntime are problematic,
by presenting an example where the controller\r\nmust act faster and faster, yet
causes no Zeno effects (say, the control\r\nactions are at times 0, 1/2, 1, 1
1/4, 2, 2 1/8, 3, 3 1/16 ,...). Such a controller is,\r\nof course, not implementable
in software. Such controllers are avoided by formulations where the controller
can cause actions only at discrete (integer) points in time. While the resulting
control problem is well- understood if the time unit, or “sampling rate” of the
controller, is fixed a priori, we define a novel, stronger formulation: the discrete-time
control problem with unknown sampling rate asks if a sampling controller exists
for some sampling rate. We prove that this problem is undecidable even in the
special case of timed automata."
acknowledgement: "Partially supported by the FNRS, Belgium, under grant 1.5.096.01.\r\nPartially
supported by the DARPA SEC grant F33615-C-98-3614, the AFOSR MURI grant F49620-00-1-0327,
the NSF Theory grant CCR-9988172, and the MARCO GSRC grant 98-DT-660.\r\nPartially
supported by a “Crédit aux chercheurs” from the Belgian National Fund for Scientific
Research."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Franck
full_name: Cassez, Franck
last_name: Cassez
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
citation:
ama: 'Cassez F, Henzinger TA, Raskin J. A comparison of control problems for timed
and hybrid systems. In: Proceedings of the 5th International Workshop on Hybrid
Systems: Computation and Control. Vol 2289. Springer; 2002:134-148. doi:10.1007/3-540-45873-5_13'
apa: 'Cassez, F., Henzinger, T. A., & Raskin, J. (2002). A comparison of control
problems for timed and hybrid systems. In Proceedings of the 5th International
Workshop on Hybrid Systems: Computation and Control (Vol. 2289, pp. 134–148).
Stanford, CA, USA: Springer. https://doi.org/10.1007/3-540-45873-5_13'
chicago: 'Cassez, Franck, Thomas A Henzinger, and Jean Raskin. “A Comparison of
Control Problems for Timed and Hybrid Systems.” In Proceedings of the 5th International
Workshop on Hybrid Systems: Computation and Control, 2289:134–48. Springer,
2002. https://doi.org/10.1007/3-540-45873-5_13.'
ieee: 'F. Cassez, T. A. Henzinger, and J. Raskin, “A comparison of control problems
for timed and hybrid systems,” in Proceedings of the 5th International Workshop
on Hybrid Systems: Computation and Control, Stanford, CA, USA, 2002, vol.
2289, pp. 134–148.'
ista: 'Cassez F, Henzinger TA, Raskin J. 2002. A comparison of control problems
for timed and hybrid systems. Proceedings of the 5th International Workshop on
Hybrid Systems: Computation and Control. HSCC: Hybrid Systems - Computation and
Control, LNCS, vol. 2289, 134–148.'
mla: 'Cassez, Franck, et al. “A Comparison of Control Problems for Timed and Hybrid
Systems.” Proceedings of the 5th International Workshop on Hybrid Systems:
Computation and Control, vol. 2289, Springer, 2002, pp. 134–48, doi:10.1007/3-540-45873-5_13.'
short: 'F. Cassez, T.A. Henzinger, J. Raskin, in:, Proceedings of the 5th International
Workshop on Hybrid Systems: Computation and Control, Springer, 2002, pp. 134–148.'
conference:
end_date: 2002-03-27
location: Stanford, CA, USA
name: 'HSCC: Hybrid Systems - Computation and Control'
start_date: 2002-03-25
date_created: 2018-12-11T12:09:30Z
date_published: 2002-03-14T00:00:00Z
date_updated: 2023-06-02T10:29:10Z
day: '14'
doi: 10.1007/3-540-45873-5_13
extern: '1'
intvolume: ' 2289'
language:
- iso: eng
month: '03'
oa_version: None
page: 134 - 148
publication: 'Proceedings of the 5th International Workshop on Hybrid Systems: Computation
and Control'
publication_identifier:
isbn:
- '9783540433217'
publication_status: published
publisher: Springer
publist_id: '144'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A comparison of control problems for timed and hybrid systems
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2289
year: '2002'
...
---
_id: '4595'
abstract:
- lang: eng
text: 'Temporal logic comes in two varieties: linear-time temporal logic assumes
implicit universal quantification over all paths that are generated by the execution
of a system; branching-time temporal logic allows explicit existential and universal
quantification over all paths. We introduce a third, more general variety of temporal
logic: alternating-time temporal logic offers selective quantification over those
paths that are possible outcomes of games, such as the game in which the system
and the environment alternate moves. While linear-time and branching-time logics
are natural specification languages for closed systems, alternating-time logics
are natural specification languages for open systems. For example, by preceding
the temporal operator "eventually" with a selective path quantifier,
we can specify that in the game between the system and the environment, the system
has a strategy to reach a certain state. The problems of receptiveness, realizability,
and controllability can be formulated as model-checking problems for alternating-time
formulas. Depending on whether or not we admit arbitrary nesting of selective
path quantifiers and temporal operators, we obtain the two alternating-time temporal
logics ATL and ATL*.ATL and ATL* are interpreted over concurrent game structures.
Every state transition of a concurrent game structure results from a choice of
moves, one for each player. The players represent individual components and the
environment of an open system. Concurrent game structures can capture various
forms of synchronous composition for open systems, and if augmented with fairness
constraints, also asynchronous composition. Over structures without fairness constraints,
the model-checking complexity of ATL is linear in the size of the game structure
and length of the formula, and the symbolic model-checking algorithm for CTL extends
with few modifications to ATL. Over structures with weak-fairness constraints,
ATL model checking requires the solution of 1-pair Rabin games, and can be done
in polynomial time. Over structures with strong-fairness constraints, ATL model
checking requires the solution of games with Boolean combinations of Büchi conditions,
and can be done in PSPACE. In the case of ATL*, the model-checking problem is
closely related to the synthesis problem for linear-time formulas, and requires
doubly exponential time.'
acknowledgement: We thank Luca de Alfaro, Kousha Etessami, Salvatore La Torre, P.
Madhusudan, Amir Pnueli, Moshe Vardi, Thomas Wilke, and Mihalis Yannakakis for helpful
discussions. We also thank Freddy Mang for comments on a draft of this manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Rajeev
full_name: Alur, Rajeev
last_name: Alur
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
citation:
ama: Alur R, Henzinger TA, Kupferman O. Alternating-time temporal logic. Journal
of the ACM. 2002;49(5):672-713. doi:10.1145/585265.585270
apa: Alur, R., Henzinger, T. A., & Kupferman, O. (2002). Alternating-time temporal
logic. Journal of the ACM. ACM. https://doi.org/10.1145/585265.585270
chicago: Alur, Rajeev, Thomas A Henzinger, and Orna Kupferman. “Alternating-Time
Temporal Logic.” Journal of the ACM. ACM, 2002. https://doi.org/10.1145/585265.585270.
ieee: R. Alur, T. A. Henzinger, and O. Kupferman, “Alternating-time temporal logic,”
Journal of the ACM, vol. 49, no. 5. ACM, pp. 672–713, 2002.
ista: Alur R, Henzinger TA, Kupferman O. 2002. Alternating-time temporal logic.
Journal of the ACM. 49(5), 672–713.
mla: Alur, Rajeev, et al. “Alternating-Time Temporal Logic.” Journal of the ACM,
vol. 49, no. 5, ACM, 2002, pp. 672–713, doi:10.1145/585265.585270.
short: R. Alur, T.A. Henzinger, O. Kupferman, Journal of the ACM 49 (2002) 672–713.
date_created: 2018-12-11T12:09:40Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-06-02T10:07:22Z
day: '01'
doi: 10.1145/585265.585270
extern: '1'
intvolume: ' 49'
issue: '5'
language:
- iso: eng
month: '09'
oa_version: None
page: 672 - 713
publication: Journal of the ACM
publication_identifier:
issn:
- 0004-5411
publication_status: published
publisher: ACM
publist_id: '110'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Alternating-time temporal logic
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 49
year: '2002'
...
---
_id: '4471'
abstract:
- lang: eng
text: The sequential synthesis problem, which is closely related to Church’s solvability
problem, asks, given a specification in the form of a binary relation between
input and output streams, for the construction of a finite-state stream transducer
that converts inputs to appropriate outputs. For efficiency reasons, practical
sequential hardware is often designed to operate without prior initialization.
Such hardware designs can be modeled by uninitialized state machines, which are
required to satisfy their specification if started from any state. In this paper
we solve the sequential synthesis problem for uninitialized systems, that is,
we construct uninitialized finite-state stream transducers. We consider specifications
given by LTL formulas, deterministic, nondeterministic, universal, and alternating
Büchi automata. We solve this uninitialized synthesis problem by reducing it to
the well-understood initialized synthesis problem. While our solution is straightforward,
it leads, for some specification formalisms, to upper bounds that are exponentially
worse than the complexity of the corresponding initialized problems. However,
we prove lower bounds to show that our simple solutions are optimal for all considered
specification formalisms. We also study the problem of deciding whether a given
specification is uninitialized, that is, if its uninitialized and initialized
synthesis problems coincide. We show that this problem has, for each specification
formalism, the same complexity as the equivalence problem.
acknowledgement: This research was supported in part by the SRC contract 99-TJ-683.003,
the DARPA contract NAG2-1214, and the NSF grant CCR-9988172.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Sriram
full_name: Krishnan, Sriram
last_name: Krishnan
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
- first_name: Freddy
full_name: Mang, Freddy
last_name: Mang
citation:
ama: 'Henzinger TA, Krishnan S, Kupferman O, Mang F. Synthesis of uninitialized
systems. In: Proceedings of the 29th International Colloquium on Automata,
Languages and Programming. Vol 2380. Springer; 2002:644-656. doi:10.1007/3-540-45465-9_55'
apa: 'Henzinger, T. A., Krishnan, S., Kupferman, O., & Mang, F. (2002). Synthesis
of uninitialized systems. In Proceedings of the 29th International Colloquium
on Automata, Languages and Programming (Vol. 2380, pp. 644–656). Malaga, Spain:
Springer. https://doi.org/10.1007/3-540-45465-9_55'
chicago: Henzinger, Thomas A, Sriram Krishnan, Orna Kupferman, and Freddy Mang.
“Synthesis of Uninitialized Systems.” In Proceedings of the 29th International
Colloquium on Automata, Languages and Programming, 2380:644–56. Springer,
2002. https://doi.org/10.1007/3-540-45465-9_55.
ieee: T. A. Henzinger, S. Krishnan, O. Kupferman, and F. Mang, “Synthesis of uninitialized
systems,” in Proceedings of the 29th International Colloquium on Automata,
Languages and Programming, Malaga, Spain, 2002, vol. 2380, pp. 644–656.
ista: 'Henzinger TA, Krishnan S, Kupferman O, Mang F. 2002. Synthesis of uninitialized
systems. Proceedings of the 29th International Colloquium on Automata, Languages
and Programming. ICALP: Automata, Languages and Programming, LNCS, vol. 2380,
644–656.'
mla: Henzinger, Thomas A., et al. “Synthesis of Uninitialized Systems.” Proceedings
of the 29th International Colloquium on Automata, Languages and Programming,
vol. 2380, Springer, 2002, pp. 644–56, doi:10.1007/3-540-45465-9_55.
short: T.A. Henzinger, S. Krishnan, O. Kupferman, F. Mang, in:, Proceedings of the
29th International Colloquium on Automata, Languages and Programming, Springer,
2002, pp. 644–656.
conference:
end_date: 2002-07-13
location: Malaga, Spain
name: 'ICALP: Automata, Languages and Programming'
start_date: 2002-07-08
date_created: 2018-12-11T12:09:01Z
date_published: 2002-06-26T00:00:00Z
date_updated: 2023-06-05T08:05:13Z
day: '26'
doi: 10.1007/3-540-45465-9_55
extern: '1'
intvolume: ' 2380'
language:
- iso: eng
month: '06'
oa_version: None
page: 644 - 656
publication: Proceedings of the 29th International Colloquium on Automata, Languages
and Programming
publication_identifier:
isbn:
- '9783540438649'
publication_status: published
publisher: Springer
publist_id: '257'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis of uninitialized systems
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2380
year: '2002'
...
---
_id: '4474'
abstract:
- lang: eng
text: 'The simulation preorder for labeled transition systems is defined locally,
and operationally, as a game that relates states with their immediate successor
states. Simulation enjoys many appealing properties. First, simulation has a denotational
characterization: system S simulates system I iff every computation tree embedded
in the unrolling of I can be embedded also in the unrolling of S. Second, simulation
has a logical characterization: S simulates I iff every universal branching-time
formula satisfied by S is satisfied also by I. It follows that simulation is a
suitable notion of implementation, and it is the coarsest abstraction of a system
that preserves universal branching-time properties. Third, based on its local
definition, simulation between finite-state systems can be checked in polynomial
time. Finally, simulation implies trace containment, which cannot be defined locally
and requires polynomial space for verification. Hence simulation is widely used
both in manual and in automatic verification. Liveness assumptions about transition
systems are typically modeled using fairness constraints. Existing notions of
simulation for fair transition systems, however, are not local, and as a result,
many appealing properties of the simulation preorder are lost. We propose a new
view of fair simulation by extending the local definition of simulation to account
for fairness: system View the MathML sourcefairly simulates system View the MathML
source iff in the simulation game, there is a strategy that matches with each
fair computation of View the MathML source a fair computation of View the MathML
source. Our definition enjoys a denotational characterization and has a logical
characterization: View the MathML source fairly simulates View the MathML source
iff every fair computation tree (whose infinite paths are fair) embedded in the
unrolling of View the MathML source can be embedded also in the unrolling of View
the MathML source or, equivalently, iff every Fair-∀AFMC formula satisfied by
View the MathML source is satisfied also by View the MathML source (∀AFMC is the
universal fragment of the alternation-free μ-calculus). The locality of the definition
leads us to a polynomial-time algorithm for checking fair simulation for finite-state
systems with weak and strong fairness constraints. Finally, fair simulation implies
fair trace containment and is therefore useful as an efficiently computable local
criterion for proving linear-time abstraction hierarchies of fair systems.'
acknowledgement: We thank Ramin Hojati, Doron Bustan, and the anonymous reviewers
for their comments on this paper.
article_processing_charge: No
article_type: original
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
- first_name: Sriram
full_name: Rajamani, Sriram
last_name: Rajamani
citation:
ama: Henzinger TA, Kupferman O, Rajamani S. Fair simulation. Information and
Computation. 2002;173(1):64-81. doi:10.1006/inco.2001.3085
apa: Henzinger, T. A., Kupferman, O., & Rajamani, S. (2002). Fair simulation.
Information and Computation. Elsevier. https://doi.org/10.1006/inco.2001.3085
chicago: Henzinger, Thomas A, Orna Kupferman, and Sriram Rajamani. “Fair Simulation.”
Information and Computation. Elsevier, 2002. https://doi.org/10.1006/inco.2001.3085.
ieee: T. A. Henzinger, O. Kupferman, and S. Rajamani, “Fair simulation,” Information
and Computation, vol. 173, no. 1. Elsevier, pp. 64–81, 2002.
ista: Henzinger TA, Kupferman O, Rajamani S. 2002. Fair simulation. Information
and Computation. 173(1), 64–81.
mla: Henzinger, Thomas A., et al. “Fair Simulation.” Information and Computation,
vol. 173, no. 1, Elsevier, 2002, pp. 64–81, doi:10.1006/inco.2001.3085.
short: T.A. Henzinger, O. Kupferman, S. Rajamani, Information and Computation 173
(2002) 64–81.
date_created: 2018-12-11T12:09:02Z
date_published: 2002-02-25T00:00:00Z
date_updated: 2023-06-05T07:53:27Z
day: '25'
doi: 10.1006/inco.2001.3085
extern: '1'
intvolume: ' 173'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0890540101930858?via%3Dihub
month: '02'
oa: 1
oa_version: Published Version
page: 64 - 81
publication: Information and Computation
publication_identifier:
issn:
- 0890-5401
publication_status: published
publisher: Elsevier
publist_id: '255'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fair simulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 173
year: '2002'
...
---
_id: '4563'
abstract:
- lang: eng
text: We present a formal methodology and tool for uncovering errors in the interaction
of software modules. Our methodology consists of a suite of languages for defining
software interfaces, and algorithms for checking interface compatibility. We focus
on interfaces that explain the method-call dependencies between software modules.
Such an interface makes assumptions about the environment in the form of call
and availability constraints. A call constraint restricts the accessibility of
local methods to certain external methods. An availability constraint restricts
the accessibility of local methods to certain states of the module. For example,
the interface for a file server with local methods open and read may assert that
a file cannot be read without having been opened. Checking interface compatibility
requires the solution of games, and in the presence of availability constraints,
of pushdown games. Based on this methodology, we have implemented a tool that
has uncovered incompatibilities in TinyOS, a small operating system for sensor
nodes in adhoc networks.
acknowledgement: This research was supported in part by the AFOSR grant F49620-00-1-0327,
the DARPA grant F33615-00-C-1693, the MARCO grant 98-DT-660, the NSF grants CCR-9988172,
CCR-0085949, CCR-0132780, the SRC grant 99-TJ-683, and the Polish KBN grant 7-T11C-027-20.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Arindam
full_name: Chakrabarti, Arindam
last_name: Chakrabarti
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Marcin
full_name: Jurdziński, Marcin
last_name: Jurdziński
- first_name: Freddy
full_name: Mang, Freddy
last_name: Mang
citation:
ama: 'Chakrabarti A, De Alfaro L, Henzinger TA, Jurdziński M, Mang F. Interface
compatibility checking for software modules. In: Proceedings of the 14th International
Conference on Computer Aided Verification. Vol 2404. Springer; 2002:428-441.
doi:10.1007/3-540-45657-0_35'
apa: 'Chakrabarti, A., De Alfaro, L., Henzinger, T. A., Jurdziński, M., & Mang,
F. (2002). Interface compatibility checking for software modules. In Proceedings
of the 14th International Conference on Computer Aided Verification (Vol.
2404, pp. 428–441). Copenhagen, Denmark: Springer. https://doi.org/10.1007/3-540-45657-0_35'
chicago: Chakrabarti, Arindam, Luca De Alfaro, Thomas A Henzinger, Marcin Jurdziński,
and Freddy Mang. “Interface Compatibility Checking for Software Modules.” In Proceedings
of the 14th International Conference on Computer Aided Verification, 2404:428–41.
Springer, 2002. https://doi.org/10.1007/3-540-45657-0_35.
ieee: A. Chakrabarti, L. De Alfaro, T. A. Henzinger, M. Jurdziński, and F. Mang,
“Interface compatibility checking for software modules,” in Proceedings of
the 14th International Conference on Computer Aided Verification, Copenhagen,
Denmark, 2002, vol. 2404, pp. 428–441.
ista: 'Chakrabarti A, De Alfaro L, Henzinger TA, Jurdziński M, Mang F. 2002. Interface
compatibility checking for software modules. Proceedings of the 14th International
Conference on Computer Aided Verification. CAV: Computer Aided Verification, LNCS,
vol. 2404, 428–441.'
mla: Chakrabarti, Arindam, et al. “Interface Compatibility Checking for Software
Modules.” Proceedings of the 14th International Conference on Computer Aided
Verification, vol. 2404, Springer, 2002, pp. 428–41, doi:10.1007/3-540-45657-0_35.
short: A. Chakrabarti, L. De Alfaro, T.A. Henzinger, M. Jurdziński, F. Mang, in:,
Proceedings of the 14th International Conference on Computer Aided Verification,
Springer, 2002, pp. 428–441.
conference:
end_date: 2002-07-31
location: Copenhagen, Denmark
name: 'CAV: Computer Aided Verification'
start_date: 2002-07-27
date_created: 2018-12-11T12:09:30Z
date_published: 2002-06-19T00:00:00Z
date_updated: 2023-06-05T07:38:10Z
day: '19'
doi: 10.1007/3-540-45657-0_35
extern: '1'
intvolume: ' 2404'
language:
- iso: eng
month: '06'
oa_version: None
page: 428 - 441
publication: Proceedings of the 14th International Conference on Computer Aided Verification
publication_identifier:
isbn:
- ' 9783540439974'
publication_status: published
publisher: Springer
publist_id: '147'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interface compatibility checking for software modules
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2404
year: '2002'
...
---
_id: '4472'
abstract:
- lang: eng
text: 'We present a methodology and tool for verifying and certifying systems code.
The verification is based on the lazy-abstraction paradigm for intertwining the
following three logical steps: construct a predicate abstraction from the code,
model check the abstraction, and automatically refine the abstraction based on
counterexample analysis. The certification is based on the proof-carrying code
paradigm. Lazy abstraction enables the automatic construction of small proof certificates.
The methodology is implemented in Blast, the Berkeley Lazy Abstraction Software
verification Tool. We describe our experience applying Blast to Linux and Windows
device drivers. Given the C code for a driver and for a temporal-safety monitor,
Blast automatically generates an easily checkable correctness certificate if the
driver satisfies the specification, and an error trace otherwise.'
acknowledgement: This work was supported in part by the NSF ITR grants CCR-0085949,
CCR-0081588, the NSF Career grant CCR-9875171, the DARPA PCES grant F33615-00-C-1693,
the MARCO GSRC grant 98-DT-660, the SRC contract 99-TJ-683, a Microsoft fellowship,
and gifts from AT&T Research and Microsoft Research.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: George
full_name: Necula, George
last_name: Necula
- first_name: Ranjit
full_name: Jhala, Ranjit
last_name: Jhala
- first_name: Grégoire
full_name: Sutre, Grégoire
last_name: Sutre
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
- first_name: Westley
full_name: Weimer, Westley
last_name: Weimer
citation:
ama: 'Henzinger TA, Necula G, Jhala R, Sutre G, Majumdar R, Weimer W. Temporal safety
proofs for systems code. In: Proceedings of the 14th International Conference
on Computer Aided Verification. Vol 2404. Springer; 2002:526-538. doi:10.1007/3-540-45657-0_45'
apa: 'Henzinger, T. A., Necula, G., Jhala, R., Sutre, G., Majumdar, R., & Weimer,
W. (2002). Temporal safety proofs for systems code. In Proceedings of the 14th
International Conference on Computer Aided Verification (Vol. 2404, pp. 526–538).
Copenhagen, Denmark: Springer. https://doi.org/10.1007/3-540-45657-0_45'
chicago: Henzinger, Thomas A, George Necula, Ranjit Jhala, Grégoire Sutre, Ritankar
Majumdar, and Westley Weimer. “Temporal Safety Proofs for Systems Code.” In Proceedings
of the 14th International Conference on Computer Aided Verification, 2404:526–38.
Springer, 2002. https://doi.org/10.1007/3-540-45657-0_45.
ieee: T. A. Henzinger, G. Necula, R. Jhala, G. Sutre, R. Majumdar, and W. Weimer,
“Temporal safety proofs for systems code,” in Proceedings of the 14th International
Conference on Computer Aided Verification, Copenhagen, Denmark, 2002, vol.
2404, pp. 526–538.
ista: 'Henzinger TA, Necula G, Jhala R, Sutre G, Majumdar R, Weimer W. 2002. Temporal
safety proofs for systems code. Proceedings of the 14th International Conference
on Computer Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 2404,
526–538.'
mla: Henzinger, Thomas A., et al. “Temporal Safety Proofs for Systems Code.” Proceedings
of the 14th International Conference on Computer Aided Verification, vol.
2404, Springer, 2002, pp. 526–38, doi:10.1007/3-540-45657-0_45.
short: T.A. Henzinger, G. Necula, R. Jhala, G. Sutre, R. Majumdar, W. Weimer, in:,
Proceedings of the 14th International Conference on Computer Aided Verification,
Springer, 2002, pp. 526–538.
conference:
end_date: 2002-07-31
location: Copenhagen, Denmark
name: 'CAV: Computer Aided Verification'
start_date: 2002-07-27
date_created: 2018-12-11T12:09:01Z
date_published: 2002-06-19T00:00:00Z
date_updated: 2023-06-05T08:11:32Z
day: '19'
doi: 10.1007/3-540-45657-0_45
extern: '1'
intvolume: ' 2404'
language:
- iso: eng
month: '06'
oa_version: None
page: 526 - 538
publication: Proceedings of the 14th International Conference on Computer Aided Verification
publication_identifier:
isbn:
- '9783540439974'
publication_status: published
publisher: Springer
publist_id: '258'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Temporal safety proofs for systems code
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2404
year: '2002'
...
---
_id: '4470'
abstract:
- lang: eng
text: Giotto is a platform-independent language for specifying software for high-performance
control applications. In this paper we present a new approach to the compilation
of Giotto. Following this approach, the Giotto compiler generates code for a virtual
machine, called the E machine, which can be ported to different platforms. The
Giotto compiler also checks if the generated E code is time safe for a given platform,
that is, if the platform offers sufficient performance to ensure that the E code
is executed in a timely fashion that conforms with the Giotto semantics. Time-safety
checking requires a schedulability analysis. We show that while for arbitrary
E code, the analysis is exponential, for E code generated from typical Giotto
programs, the analysis is polynomial. This supports our claim that Giotto identifies
a useful fragment of embedded programs.
acknowledgement: Supported in part by the DARPA SEC grant F33615-C-98-3614, MARCO
GSRC grant 98-DT-660, AFOSR MURI grant F49620-00-1-0327, NSF grant CCR-9988172,
and a Microsoft Research Fellowship.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Christoph
full_name: Kirsch, Christoph
last_name: Kirsch
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
- first_name: Slobodan
full_name: Matic, Slobodan
last_name: Matic
citation:
ama: 'Henzinger TA, Kirsch C, Majumdar R, Matic S. Time-safety checking for embedded
programs. In: Proceedings of the 2nd International Conference on Embedded Software.
Vol 2491. ACM; 2002:76-92. doi:10.1007/3-540-45828-X_7'
apa: 'Henzinger, T. A., Kirsch, C., Majumdar, R., & Matic, S. (2002). Time-safety
checking for embedded programs. In Proceedings of the 2nd International Conference
on Embedded Software (Vol. 2491, pp. 76–92). Grenoble, France: ACM. https://doi.org/10.1007/3-540-45828-X_7'
chicago: Henzinger, Thomas A, Christoph Kirsch, Ritankar Majumdar, and Slobodan
Matic. “Time-Safety Checking for Embedded Programs.” In Proceedings of the
2nd International Conference on Embedded Software, 2491:76–92. ACM, 2002.
https://doi.org/10.1007/3-540-45828-X_7.
ieee: T. A. Henzinger, C. Kirsch, R. Majumdar, and S. Matic, “Time-safety checking
for embedded programs,” in Proceedings of the 2nd International Conference
on Embedded Software, Grenoble, France, 2002, vol. 2491, pp. 76–92.
ista: 'Henzinger TA, Kirsch C, Majumdar R, Matic S. 2002. Time-safety checking for
embedded programs. Proceedings of the 2nd International Conference on Embedded
Software. EMSOFT: Embedded Software , LNCS, vol. 2491, 76–92.'
mla: Henzinger, Thomas A., et al. “Time-Safety Checking for Embedded Programs.”
Proceedings of the 2nd International Conference on Embedded Software, vol.
2491, ACM, 2002, pp. 76–92, doi:10.1007/3-540-45828-X_7.
short: T.A. Henzinger, C. Kirsch, R. Majumdar, S. Matic, in:, Proceedings of the
2nd International Conference on Embedded Software, ACM, 2002, pp. 76–92.
conference:
end_date: 2002-10-09
location: Grenoble, France
name: 'EMSOFT: Embedded Software '
start_date: 2002-10-07
date_created: 2018-12-11T12:09:01Z
date_published: 2002-09-25T00:00:00Z
date_updated: 2023-06-05T08:50:59Z
day: '25'
doi: 10.1007/3-540-45828-X_7
extern: '1'
intvolume: ' 2491'
language:
- iso: eng
month: '09'
oa_version: None
page: 76 - 92
publication: Proceedings of the 2nd International Conference on Embedded Software
publication_identifier:
isbn:
- '9783540443070'
publication_status: published
publisher: ACM
publist_id: '259'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Time-safety checking for embedded programs
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2491
year: '2002'
...
---
_id: '4444'
abstract:
- lang: eng
text: The Embedded Machine is a virtual machine that mediates in real time the interaction
between software processes and physical processes. It separates the compilation
of embedded programs into two phases. The first, platform-independent compiler
phase generates E code (code executed by the Embedded Machine), which supervises
the timing ---not the scheduling--- of application tasks relative to external
events, such as clock ticks and sensor interrupts. E~code is portable and exhibits,
given an input behavior, predictable (i.e., deterministic) timing and output behavior.
The second, platform-dependent compiler phase checks the time safety of the E
code, that is, whether platform performance (determined by the hardware) and platform
utilization (determined by the scheduler of the operating system) enable its timely
execution. We have used the Embedded Machine to compile and execute high-performance
control applications written in Giotto, such as the flight control system of an
autonomous model helicopter.
acknowledgement: This research was supported in part by the DARPA SEC grant F33615-C-98-3614,
the MARCO GSRC grant 98-DT- 660, the AFOSR MURI grant F49620-00-1-0327, and the
NSF ITR grant CCR-0085949.
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Christoph
full_name: Kirsch, Christoph
last_name: Kirsch
citation:
ama: 'Henzinger TA, Kirsch C. The embedded machine: predictable, portable real-time
code. In: Proceedings of the ACM SIGPLAN 2002 Conference on Programming Language
Design and Implementation. ACM; 2002:315-326. doi:10.1145/512529.512567'
apa: 'Henzinger, T. A., & Kirsch, C. (2002). The embedded machine: predictable,
portable real-time code. In Proceedings of the ACM SIGPLAN 2002 conference
on Programming language design and implementation (pp. 315–326). Berlin, Germany:
ACM. https://doi.org/10.1145/512529.512567'
chicago: 'Henzinger, Thomas A, and Christoph Kirsch. “The Embedded Machine: Predictable,
Portable Real-Time Code.” In Proceedings of the ACM SIGPLAN 2002 Conference
on Programming Language Design and Implementation, 315–26. ACM, 2002. https://doi.org/10.1145/512529.512567.'
ieee: 'T. A. Henzinger and C. Kirsch, “The embedded machine: predictable, portable
real-time code,” in Proceedings of the ACM SIGPLAN 2002 conference on Programming
language design and implementation, Berlin, Germany, 2002, pp. 315–326.'
ista: 'Henzinger TA, Kirsch C. 2002. The embedded machine: predictable, portable
real-time code. Proceedings of the ACM SIGPLAN 2002 conference on Programming
language design and implementation. PLDI: Programming Languages Design and Implementation,
315–326.'
mla: 'Henzinger, Thomas A., and Christoph Kirsch. “The Embedded Machine: Predictable,
Portable Real-Time Code.” Proceedings of the ACM SIGPLAN 2002 Conference on
Programming Language Design and Implementation, ACM, 2002, pp. 315–26, doi:10.1145/512529.512567.'
short: T.A. Henzinger, C. Kirsch, in:, Proceedings of the ACM SIGPLAN 2002 Conference
on Programming Language Design and Implementation, ACM, 2002, pp. 315–326.
conference:
end_date: 2002-06-19
location: Berlin, Germany
name: 'PLDI: Programming Languages Design and Implementation'
start_date: 2002-06-17
date_created: 2018-12-11T12:08:53Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-05T09:02:23Z
day: '01'
doi: 10.1145/512529.512567
extern: '1'
language:
- iso: eng
month: '06'
oa_version: None
page: 315 - 326
publication: Proceedings of the ACM SIGPLAN 2002 conference on Programming language
design and implementation
publication_identifier:
isbn:
- '9781581134636'
publication_status: published
publisher: ACM
publist_id: '284'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The embedded machine: predictable, portable real-time code'
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '4476'
abstract:
- lang: eng
text: 'One approach to model checking software is based on the abstract-check-refine
paradigm: build an abstract model, then check the desired property, and if the
check fails, refine the model and start over. We introduce the concept of lazy
abstraction to integrate and optimize the three phases of the abstract-check-refine
loop. Lazy abstraction continuously builds and refines a single abstract model
on demand, driven by the model checker, so that different parts of the model may
exhibit different degrees of precision, namely just enough to verify the desired
property. We present an algorithm for model checking safety properties using lazy
abstraction and describe an implementation of the algorithm applied to C programs.
We also provide sufficient conditions for the termination of the method.'
acknowledgement: "We thank Wes Weimer and Jeff Foster for many useful discussions.
\r\n"
article_processing_charge: No
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Ranjit
full_name: Jhala, Ranjit
last_name: Jhala
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
- first_name: Grégoire
full_name: Sutre, Grégoire
last_name: Sutre
citation:
ama: 'Henzinger TA, Jhala R, Majumdar R, Sutre G. Lazy abstraction. In: Proceedings
of the 29th ACM SIGPLAN-SIGACT Symposium on Principles of Programming Languages.
ACM; 2002:58-70. doi:10.1145/503272.503279'
apa: 'Henzinger, T. A., Jhala, R., Majumdar, R., & Sutre, G. (2002). Lazy abstraction.
In Proceedings of the 29th ACM SIGPLAN-SIGACT symposium on Principles of programming
languages (pp. 58–70). Portland, OR, USA: ACM. https://doi.org/10.1145/503272.503279'
chicago: Henzinger, Thomas A, Ranjit Jhala, Ritankar Majumdar, and Grégoire Sutre.
“Lazy Abstraction.” In Proceedings of the 29th ACM SIGPLAN-SIGACT Symposium
on Principles of Programming Languages, 58–70. ACM, 2002. https://doi.org/10.1145/503272.503279.
ieee: T. A. Henzinger, R. Jhala, R. Majumdar, and G. Sutre, “Lazy abstraction,”
in Proceedings of the 29th ACM SIGPLAN-SIGACT symposium on Principles of programming
languages, Portland, OR, USA, 2002, pp. 58–70.
ista: 'Henzinger TA, Jhala R, Majumdar R, Sutre G. 2002. Lazy abstraction. Proceedings
of the 29th ACM SIGPLAN-SIGACT symposium on Principles of programming languages.
POPL: Principles of Programming Languages, 58–70.'
mla: Henzinger, Thomas A., et al. “Lazy Abstraction.” Proceedings of the 29th
ACM SIGPLAN-SIGACT Symposium on Principles of Programming Languages, ACM,
2002, pp. 58–70, doi:10.1145/503272.503279.
short: T.A. Henzinger, R. Jhala, R. Majumdar, G. Sutre, in:, Proceedings of the
29th ACM SIGPLAN-SIGACT Symposium on Principles of Programming Languages, ACM,
2002, pp. 58–70.
conference:
end_date: 2002-01-18
location: Portland, OR, USA
name: 'POPL: Principles of Programming Languages'
start_date: 2002-01-16
date_created: 2018-12-11T12:09:03Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-05T07:45:53Z
day: '01'
doi: 10.1145/503272.503279
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 58 - 70
publication: Proceedings of the 29th ACM SIGPLAN-SIGACT symposium on Principles of
programming languages
publication_identifier:
isbn:
- '9781581134506'
publication_status: published
publisher: ACM
publist_id: '254'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lazy abstraction
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '4473'
abstract:
- lang: eng
text: 'The simulation preorder on state transition systems is widely accepted as
a useful notion of refinement, both in its own right and as an efficiently checkable
sufficient condition for trace containment. For composite systems, due to the
exponential explosion of the state space, there is a need for decomposing a simulation
check of the form P ≤s Q, denoting "P is simulated by Q," into simpler
simulation checks on the components of P and Q. We present an assume-guarantee
rule that enables such a decomposition. To the best of our knowledge, this is
the first assume-guarantee rule that applies to a refinement relation different
from trace containment. Our rule is circular, and its soundness proof requires
induction on trace trees. The proof is constructive: given simulation relations
that witness the simulation preorder between corresponding components of P and
Q, we provide a procedure for constructing a witness relation for P ≤s Q. We also
extend our assume-guarantee rule to account for fairness constraints on transition
systems.'
article_processing_charge: No
article_type: original
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Shaz
full_name: Qadeer, Shaz
last_name: Qadeer
- first_name: Sriram
full_name: Rajamani, Sriram
last_name: Rajamani
- first_name: Serdar
full_name: Tasiran, Serdar
last_name: Tasiran
citation:
ama: Henzinger TA, Qadeer S, Rajamani S, Tasiran S. An assume-guarantee rule for
checking simulation. ACM Transactions on Programming Languages and Systems
(TOPLAS). 2002;24(1):51-64. doi:10.1145/509705.509707
apa: Henzinger, T. A., Qadeer, S., Rajamani, S., & Tasiran, S. (2002). An assume-guarantee
rule for checking simulation. ACM Transactions on Programming Languages and
Systems (TOPLAS). ACM. https://doi.org/10.1145/509705.509707
chicago: Henzinger, Thomas A, Shaz Qadeer, Sriram Rajamani, and Serdar Tasiran.
“An Assume-Guarantee Rule for Checking Simulation.” ACM Transactions on Programming
Languages and Systems (TOPLAS). ACM, 2002. https://doi.org/10.1145/509705.509707.
ieee: T. A. Henzinger, S. Qadeer, S. Rajamani, and S. Tasiran, “An assume-guarantee
rule for checking simulation,” ACM Transactions on Programming Languages and
Systems (TOPLAS), vol. 24, no. 1. ACM, pp. 51–64, 2002.
ista: Henzinger TA, Qadeer S, Rajamani S, Tasiran S. 2002. An assume-guarantee rule
for checking simulation. ACM Transactions on Programming Languages and Systems
(TOPLAS). 24(1), 51–64.
mla: Henzinger, Thomas A., et al. “An Assume-Guarantee Rule for Checking Simulation.”
ACM Transactions on Programming Languages and Systems (TOPLAS), vol. 24,
no. 1, ACM, 2002, pp. 51–64, doi:10.1145/509705.509707.
short: T.A. Henzinger, S. Qadeer, S. Rajamani, S. Tasiran, ACM Transactions on Programming
Languages and Systems (TOPLAS) 24 (2002) 51–64.
date_created: 2018-12-11T12:09:02Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-05T07:59:47Z
day: '01'
doi: 10.1145/509705.509707
extern: '1'
intvolume: ' 24'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 51 - 64
publication: ACM Transactions on Programming Languages and Systems (TOPLAS)
publication_identifier:
issn:
- 0164-0925
publication_status: published
publisher: ACM
publist_id: '256'
quality_controlled: '1'
scopus_import: '1'
status: public
title: An assume-guarantee rule for checking simulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 24
year: '2002'
...
---
_id: '4423'
abstract:
- lang: eng
text: Automation control systems typically incorporate legacy code and components
that were originally designed to operate independently. Furthermore, they operate
under stringent safety and timing constraints. Current design strategies deal
with these requirements and characteristics with ad hoc approaches. In particular,
when designing control laws, implementation constraints are often ignored or cursorily
estimated. Indeed, costly redesigns are needed after a prototype of the control
system is built due to missed timing constraints and subtle transient errors.
In this paper, we use the concepts of platform-based design, and the Giotto programming
language, to develop a methodology for the design of automation control systems
that builds in modularity and correct-by-construction procedures. We illustrate
our strategy by describing the (successful) application of the methodology to
the design of a time-based control system for a rotorcraft Uninhabited Aerial
Vehicle (UAV).
acknowledgement: "Research supported in part by DARPA under contract no.F33615-98-C-3614,
Software Enabled Control, administered by\r\nAFRL, Dayton OH."
article_processing_charge: No
author:
- first_name: Benjamin
full_name: Horowitz, Benjamin
last_name: Horowitz
- first_name: Judith
full_name: Liebman, Judith
last_name: Liebman
- first_name: Cedric
full_name: Ma, Cedric
last_name: Ma
- first_name: T John
full_name: Koo, T John
last_name: Koo
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Alberto
full_name: Sangiovanni Vincentelli, Alberto
last_name: Sangiovanni Vincentelli
- first_name: Shankar
full_name: Sastry, Shankar
last_name: Sastry
citation:
ama: 'Horowitz B, Liebman J, Ma C, et al. Embedded software design and system integration
for rotorcraft UAV using platforms. In: Proceedings of the 15th Triennial World
Congress of the International Federation of Automatic Control. Vol 15. Elsevier;
2002. doi:10.3182/20020721-6-ES-1901.01628'
apa: 'Horowitz, B., Liebman, J., Ma, C., Koo, T. J., Henzinger, T. A., Sangiovanni
Vincentelli, A., & Sastry, S. (2002). Embedded software design and system
integration for rotorcraft UAV using platforms. In Proceedings of the 15th
Triennial World Congress of the International Federation of Automatic Control
(Vol. 15). Barcelona, Spain: Elsevier. https://doi.org/10.3182/20020721-6-ES-1901.01628'
chicago: Horowitz, Benjamin, Judith Liebman, Cedric Ma, T John Koo, Thomas A Henzinger,
Alberto Sangiovanni Vincentelli, and Shankar Sastry. “Embedded Software Design
and System Integration for Rotorcraft UAV Using Platforms.” In Proceedings
of the 15th Triennial World Congress of the International Federation of Automatic
Control, Vol. 15. Elsevier, 2002. https://doi.org/10.3182/20020721-6-ES-1901.01628.
ieee: B. Horowitz et al., “Embedded software design and system integration
for rotorcraft UAV using platforms,” in Proceedings of the 15th Triennial World
Congress of the International Federation of Automatic Control, Barcelona,
Spain, 2002, vol. 15, no. 1.
ista: 'Horowitz B, Liebman J, Ma C, Koo TJ, Henzinger TA, Sangiovanni Vincentelli
A, Sastry S. 2002. Embedded software design and system integration for rotorcraft
UAV using platforms. Proceedings of the 15th Triennial World Congress of the International
Federation of Automatic Control. IFAC: World Congress on Automatic Control vol.
15.'
mla: Horowitz, Benjamin, et al. “Embedded Software Design and System Integration
for Rotorcraft UAV Using Platforms.” Proceedings of the 15th Triennial World
Congress of the International Federation of Automatic Control, vol. 15, no.
1, Elsevier, 2002, doi:10.3182/20020721-6-ES-1901.01628.
short: B. Horowitz, J. Liebman, C. Ma, T.J. Koo, T.A. Henzinger, A. Sangiovanni
Vincentelli, S. Sastry, in:, Proceedings of the 15th Triennial World Congress
of the International Federation of Automatic Control, Elsevier, 2002.
conference:
end_date: 2002-07-26
location: Barcelona, Spain
name: 'IFAC: World Congress on Automatic Control'
start_date: 2002-07-21
date_created: 2018-12-11T12:08:47Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2023-06-05T09:55:10Z
day: '01'
doi: 10.3182/20020721-6-ES-1901.01628
extern: '1'
intvolume: ' 15'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
publication: Proceedings of the 15th Triennial World Congress of the International
Federation of Automatic Control
publication_identifier:
issn:
- 1474-6670
publication_status: published
publisher: Elsevier
publist_id: '306'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Embedded software design and system integration for rotorcraft UAV using platforms
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2002'
...
---
_id: '4421'
abstract:
- lang: eng
text: We demonstrate the feasibility and benefits of Giotto-based control software
development by reimplementing the autopilot system of an autonomously flying model
helicopter. Giotto offers a clean separation between the platform-independent
concerns of software functionality and I/O timing, and the platform-dependent
concerns of software scheduling and execution. Functionality code such as code
computing control laws can be generated automatically from Simulink models or,
as in the case of this project, inherited from a legacy system. I/O timing code
is generated automatically from Giotto models that specify real-time requirements
such as task frequencies and actuator update rates. We extend Simulink to support
the design of Giotto models, and from these models, the automatic generation of
Giotto code that supervises the interaction of the functionality code with the
physical environment. The Giotto compiler performs a schedulability analysis on
the Giotto code, and generates timing code for the helicopter platform. The Giotto
methodology guarantees the stringent hard real-time requirements of the autopilot
system, and at the same time supports the automation of the software development
process in a way that produces a transparent software architecture with predictable
behavior and reusable components.
acknowledgement: This research was supported in part by the DARPA SEC grant F33615-C-98-3614,
the MARCO GSRC grant 98-DT-660, and the AFOSR MURI grant F49620-00-1-0327.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Christoph
full_name: Kirsch, Christoph
last_name: Kirsch
- first_name: Marco
full_name: Sanvido, Marco
last_name: Sanvido
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Wolfgang
full_name: Pree, Wolfgang
last_name: Pree
citation:
ama: 'Kirsch C, Sanvido M, Henzinger TA, Pree W. A Giotto-based helicopter control
system. In: Proceedings of the 2nd International Conference on Embedded Software.
Vol 2491. ACM; 2002:46-60. doi:10.1007/3-540-45828-X_5'
apa: 'Kirsch, C., Sanvido, M., Henzinger, T. A., & Pree, W. (2002). A Giotto-based
helicopter control system. In Proceedings of the 2nd International Conference
on Embedded Software (Vol. 2491, pp. 46–60). Grenoble, France: ACM. https://doi.org/10.1007/3-540-45828-X_5'
chicago: Kirsch, Christoph, Marco Sanvido, Thomas A Henzinger, and Wolfgang Pree.
“A Giotto-Based Helicopter Control System.” In Proceedings of the 2nd International
Conference on Embedded Software, 2491:46–60. ACM, 2002. https://doi.org/10.1007/3-540-45828-X_5.
ieee: C. Kirsch, M. Sanvido, T. A. Henzinger, and W. Pree, “A Giotto-based helicopter
control system,” in Proceedings of the 2nd International Conference on Embedded
Software, Grenoble, France, 2002, vol. 2491, pp. 46–60.
ista: 'Kirsch C, Sanvido M, Henzinger TA, Pree W. 2002. A Giotto-based helicopter
control system. Proceedings of the 2nd International Conference on Embedded Software.
EMSOFT: Embedded Software , LNCS, vol. 2491, 46–60.'
mla: Kirsch, Christoph, et al. “A Giotto-Based Helicopter Control System.” Proceedings
of the 2nd International Conference on Embedded Software, vol. 2491, ACM,
2002, pp. 46–60, doi:10.1007/3-540-45828-X_5.
short: C. Kirsch, M. Sanvido, T.A. Henzinger, W. Pree, in:, Proceedings of the 2nd
International Conference on Embedded Software, ACM, 2002, pp. 46–60.
conference:
end_date: 2002-10-09
location: Grenoble, France
name: 'EMSOFT: Embedded Software '
start_date: 2002-10-07
date_created: 2018-12-11T12:08:46Z
date_published: 2002-09-25T00:00:00Z
date_updated: 2023-06-05T13:07:20Z
day: '25'
doi: 10.1007/3-540-45828-X_5
extern: '1'
intvolume: ' 2491'
language:
- iso: eng
month: '09'
oa_version: None
page: 46 - 60
publication: Proceedings of the 2nd International Conference on Embedded Software
publication_identifier:
isbn:
- '9783540443070'
publication_status: published
publisher: ACM
publist_id: '310'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A Giotto-based helicopter control system
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2491
year: '2002'
...
---
_id: '4422'
abstract:
- lang: eng
text: "Behavioral properties of open systems can be formalized as objectives in
two-player games. Turn-based games model asynchronous interaction between the
players (the system and its environment) by interleaving their moves. Concurrent
games model synchronous interaction: the players always move simultaneously. Infinitary
winning criteria are considered: Büchi, co-Büchi, and more general parity conditions.
A generalization of determinacy for parity games to concurrent parity games demands
probabilistic (mixed) strategies: either player 1 has a mixed strategy to win
with probability 1 (almost-sure winning), or player 2 has a mixed strategy to
win with positive probability.\r\nThis work provides efficient reductions of concurrent
probabilistic Büchi and co-Büchi games to turn-based games with Büchi condition
and parity winning condition with three priorities, respectively. From a theoretical
point of view, the latter reduction shows that one can trade the probabilistic
nature of almost-sure winning for a more general parity (fairness) condition.
The reductions improve understanding of concurrent games and provide an alternative
simple proof of determinacy of concurrent Büchi and co-Büchi games. From a practical
point of view, the reductions turn solvers of turn-based games into solvers of
concurrent probabilistic games. Thus improvements in the well-studied algorithms
for the former carry over immediately to the latter. In particular, a recent improvement
in the complexity of solving turn-based parity games yields an improvement in
time complexity of solving concurrent probabilistic co-Büchi games from cubic
to quadratic."
acknowledgement: This research was supported in part by the Polish KBN grant 7-T11C-027-20,
the AFOSR MURI grant F49620-00-1-0327, and the NSF Theory grant CCR-9988172.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Marcin
full_name: Jurdziński, Marcin
last_name: Jurdziński
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Jurdziński M, Kupferman O, Henzinger TA. Trading probability for fairness.
In: Proceedings of the 16th International Workshop on Computer Science Logic.
Vol 2471. Springer; 2002:292-305. doi:10.1007/3-540-45793-3_20'
apa: 'Jurdziński, M., Kupferman, O., & Henzinger, T. A. (2002). Trading probability
for fairness. In Proceedings of the 16th International Workshop on Computer
Science Logic (Vol. 2471, pp. 292–305). Edinburgh, Scotland: Springer. https://doi.org/10.1007/3-540-45793-3_20'
chicago: Jurdziński, Marcin, Orna Kupferman, and Thomas A Henzinger. “Trading Probability
for Fairness.” In Proceedings of the 16th International Workshop on Computer
Science Logic, 2471:292–305. Springer, 2002. https://doi.org/10.1007/3-540-45793-3_20.
ieee: M. Jurdziński, O. Kupferman, and T. A. Henzinger, “Trading probability for
fairness,” in Proceedings of the 16th International Workshop on Computer Science
Logic, Edinburgh, Scotland, 2002, vol. 2471, pp. 292–305.
ista: 'Jurdziński M, Kupferman O, Henzinger TA. 2002. Trading probability for fairness.
Proceedings of the 16th International Workshop on Computer Science Logic. CSL:
Computer Science Logic, LNCS, vol. 2471, 292–305.'
mla: Jurdziński, Marcin, et al. “Trading Probability for Fairness.” Proceedings
of the 16th International Workshop on Computer Science Logic, vol. 2471, Springer,
2002, pp. 292–305, doi:10.1007/3-540-45793-3_20.
short: M. Jurdziński, O. Kupferman, T.A. Henzinger, in:, Proceedings of the 16th
International Workshop on Computer Science Logic, Springer, 2002, pp. 292–305.
conference:
location: Edinburgh, Scotland
name: 'CSL: Computer Science Logic'
date_created: 2018-12-11T12:08:46Z
date_published: 2002-09-09T00:00:00Z
date_updated: 2023-06-05T10:02:54Z
day: '09'
doi: 10.1007/3-540-45793-3_20
extern: '1'
intvolume: ' 2471'
language:
- iso: eng
month: '09'
oa_version: None
page: 292 - 305
publication: Proceedings of the 16th International Workshop on Computer Science Logic
publication_identifier:
isbn:
- '9783540442400'
publication_status: published
publisher: Springer
publist_id: '308'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Trading probability for fairness
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2471
year: '2002'
...
---
_id: '4413'
abstract:
- lang: eng
text: 'An essential problem in component-based design is how to compose components
designed in isolation. Several approaches have been proposed for specifying component
interfaces that capture behavioral aspects such as interaction protocols, and
for verifying interface compatibility. Likewise, several approaches have been
developed for synthesizing converters between incompatible protocols. In this
paper, we introduce the notion of adaptability as the property that two interfaces
have when they can be made compatible by communicating through a converter that
meets specified requirements. We show that verifying adaptability and synthesizing
an appropriate converter are two faces of the same coin: adaptability can be formalized
and solved using a game-theoretic framework, and then the converter can be synthesized
as a strategy that always wins the game. Finally we show that this framework can
be related to the rectification problem in trace theory.'
acknowledgement: "The authors would like to thank Jerry Burch of the Cadence Berkeley
Labs for many insightful discussions and suggestions.\r\n"
article_processing_charge: No
author:
- first_name: Roberto
full_name: Passerone, Roberto
last_name: Passerone
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Alberto
full_name: Sangiovanni Vincentelli, Alberto
last_name: Sangiovanni Vincentelli
citation:
ama: 'Passerone R, De Alfaro L, Henzinger TA, Sangiovanni Vincentelli A. Convertibility
verification and converter synthesis: Two faces of the same coin. In: Proceedings
of the 11th IEEE/ACM International Conference on Computer-Aided Design. IEEE;
2002:132-139. doi:10.1145/774572.774592'
apa: 'Passerone, R., De Alfaro, L., Henzinger, T. A., & Sangiovanni Vincentelli,
A. (2002). Convertibility verification and converter synthesis: Two faces of the
same coin. In Proceedings of the 11th IEEE/ACM international conference on
Computer-aided design (pp. 132–139). San Jose, CA, USA: IEEE. https://doi.org/10.1145/774572.774592'
chicago: 'Passerone, Roberto, Luca De Alfaro, Thomas A Henzinger, and Alberto Sangiovanni
Vincentelli. “Convertibility Verification and Converter Synthesis: Two Faces of
the Same Coin.” In Proceedings of the 11th IEEE/ACM International Conference
on Computer-Aided Design, 132–39. IEEE, 2002. https://doi.org/10.1145/774572.774592.'
ieee: 'R. Passerone, L. De Alfaro, T. A. Henzinger, and A. Sangiovanni Vincentelli,
“Convertibility verification and converter synthesis: Two faces of the same coin,”
in Proceedings of the 11th IEEE/ACM international conference on Computer-aided
design, San Jose, CA, USA, 2002, pp. 132–139.'
ista: 'Passerone R, De Alfaro L, Henzinger TA, Sangiovanni Vincentelli A. 2002.
Convertibility verification and converter synthesis: Two faces of the same coin.
Proceedings of the 11th IEEE/ACM international conference on Computer-aided design.
ICCAD: Computer-Aided Design, 132–139.'
mla: 'Passerone, Roberto, et al. “Convertibility Verification and Converter Synthesis:
Two Faces of the Same Coin.” Proceedings of the 11th IEEE/ACM International
Conference on Computer-Aided Design, IEEE, 2002, pp. 132–39, doi:10.1145/774572.774592.'
short: R. Passerone, L. De Alfaro, T.A. Henzinger, A. Sangiovanni Vincentelli, in:,
Proceedings of the 11th IEEE/ACM International Conference on Computer-Aided Design,
IEEE, 2002, pp. 132–139.
conference:
end_date: 2002-11-14
location: San Jose, CA, USA
name: 'ICCAD: Computer-Aided Design'
start_date: 2002-11-10
date_created: 2018-12-11T12:08:44Z
date_published: 2002-11-01T00:00:00Z
date_updated: 2023-06-05T14:21:46Z
day: '01'
doi: 10.1145/774572.774592
extern: '1'
language:
- iso: eng
month: '11'
oa_version: None
page: 132 - 139
publication: Proceedings of the 11th IEEE/ACM international conference on Computer-aided
design
publication_identifier:
isbn:
- '9780780376076'
publication_status: published
publisher: IEEE
publist_id: '318'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Convertibility verification and converter synthesis: Two faces of the same
coin'
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '4262'
abstract:
- lang: eng
text: Natural populations are structured spatially into local populations and genetically
into diverse ‘genetic backgrounds’ defined by different combinations of selected
alleles. If selection maintains genetic backgrounds at constant frequency then
neutral diversity is enhanced. By contrast, if background frequencies fluctuate
then diversity is reduced. Provided that the population size of each background
is large enough, these effects can be described by the structured coalescent process.
Almost all the extant results based on the coalescent deal with a single selected
locus. Yet we know that very large numbers of genes are under selection and that
any substantial effects are likely to be due to the cumulative effects of many
loci. Here, we set up a general framework for the extension of the coalescent
to multilocus scenarios and we use it to study the simplest model, where strong
balancing selection acting on a set of n loci maintains 2n backgrounds at constant
frequencies and at linkage equilibrium. Analytical results show that the expected
linked neutral diversity increases exponentially with the number of selected loci
and can become extremely large. However, simulation results reveal that the structured
coalescent approach breaks down when the number of backgrounds approaches the
population size, because of stochastic fluctuations in background frequencies.
A new method is needed to extend the structured coalescent to cases with large
numbers of backgrounds.
acknowledgement: "We thank B. Charlesworth, D. Charlesworth and F. Depaulis for valuable
discussion and criticism. We are also\r\ngrateful to an anonymous reviewer, who
pointed out an imprecision in the original manuscript. This work was\r\nsupported
by the BBSRC."
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Arcadio
full_name: Navarro, Arcadio
last_name: Navarro
citation:
ama: 'Barton NH, Navarro A. Extending the coalescent to multilocus systems: the
case of balancing selection. Genetical Research. 2002;79(2):129-139. doi:10.1017/S0016672301005493'
apa: 'Barton, N. H., & Navarro, A. (2002). Extending the coalescent to multilocus
systems: the case of balancing selection. Genetical Research. Cambridge
University Press. https://doi.org/10.1017/S0016672301005493'
chicago: 'Barton, Nicholas H, and Arcadio Navarro. “Extending the Coalescent to
Multilocus Systems: The Case of Balancing Selection.” Genetical Research.
Cambridge University Press, 2002. https://doi.org/10.1017/S0016672301005493.'
ieee: 'N. H. Barton and A. Navarro, “Extending the coalescent to multilocus systems:
the case of balancing selection,” Genetical Research, vol. 79, no. 2. Cambridge
University Press, pp. 129–139, 2002.'
ista: 'Barton NH, Navarro A. 2002. Extending the coalescent to multilocus systems:
the case of balancing selection. Genetical Research. 79(2), 129–139.'
mla: 'Barton, Nicholas H., and Arcadio Navarro. “Extending the Coalescent to Multilocus
Systems: The Case of Balancing Selection.” Genetical Research, vol. 79,
no. 2, Cambridge University Press, 2002, pp. 129–39, doi:10.1017/S0016672301005493.'
short: N.H. Barton, A. Navarro, Genetical Research 79 (2002) 129–139.
date_created: 2018-12-11T12:07:55Z
date_published: 2002-05-23T00:00:00Z
date_updated: 2023-06-06T11:23:19Z
day: '23'
doi: 10.1017/S0016672301005493
extern: '1'
external_id:
pmid:
- '12073551'
intvolume: ' 79'
issue: '2'
language:
- iso: eng
month: '05'
oa_version: None
page: 129 - 139
pmid: 1
publication: Genetical Research
publication_identifier:
issn:
- 0016-6723
publication_status: published
publisher: Cambridge University Press
publist_id: '1832'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Extending the coalescent to multilocus systems: the case of balancing selection'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 79
year: '2002'
...
---
_id: '4260'
abstract:
- lang: eng
text: 'We calculate the fixation probability of a beneficial allele that arises
as the result of a unique mutation in an asexual population that is subject to
recurrent deleterious mutation at rate U. Our analysis is an extension of previous
works, which make a biologically restrictive assumption that selection against
deleterious alleles is stronger than that on the beneficial allele of interest.
We show that when selection against deleterious alleles is weak, beneficial alleles
that confer a selective advantage that is small relative to U have greatly reduced
probabilities of fixation. We discuss the consequences of this effect for the
distribution of effects of alleles fixed during adaptation. We show that a selective
sweep will increase the fixation probabilities of other beneficial mutations arising
during some short interval afterward. We use the calculated fixation probabilities
to estimate the expected rate of fitness improvement in an asexual population
when beneficial alleles arise continually at some low rate proportional to U.
We estimate the rate of mutation that is optimal in the sense that it maximizes
this rate of fitness improvement. Again, this analysis relaxes the assumption
made previously that selection against deleterious alleles is stronger than on
beneficial alleles. '
acknowledgement: "We thank Brian Charlesworth, Arcadi Navarro, Allen Orr, Sally Otto,
Mario Pineda-Krch, Rosie Redfield, Olivier Tenaillon, and two anonymous reviewers
for discussions and/or helpful comments on the\r\nmanuscript. T.J. is supported
by Wellcome Trust International Prize Travelling Research Fellowship no. 061530.
N.B. is supported by the Biotechnology and Biological Sciences Research Council
and by the Natural Environment Research Council."
article_processing_charge: No
article_type: original
author:
- first_name: Toby
full_name: Johnson, Toby
last_name: Johnson
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Johnson T, Barton NH. The effect of deleterious alleles on adaptation in asexual
populations. Genetics. 2002;162(1):395-411. doi:10.1093/genetics/162.1.395
apa: Johnson, T., & Barton, N. H. (2002). The effect of deleterious alleles
on adaptation in asexual populations. Genetics. Genetics Society of America.
https://doi.org/10.1093/genetics/162.1.395
chicago: Johnson, Toby, and Nicholas H Barton. “The Effect of Deleterious Alleles
on Adaptation in Asexual Populations.” Genetics. Genetics Society of America,
2002. https://doi.org/10.1093/genetics/162.1.395.
ieee: T. Johnson and N. H. Barton, “The effect of deleterious alleles on adaptation
in asexual populations,” Genetics, vol. 162, no. 1. Genetics Society of
America, pp. 395–411, 2002.
ista: Johnson T, Barton NH. 2002. The effect of deleterious alleles on adaptation
in asexual populations. Genetics. 162(1), 395–411.
mla: Johnson, Toby, and Nicholas H. Barton. “The Effect of Deleterious Alleles on
Adaptation in Asexual Populations.” Genetics, vol. 162, no. 1, Genetics
Society of America, 2002, pp. 395–411, doi:10.1093/genetics/162.1.395.
short: T. Johnson, N.H. Barton, Genetics 162 (2002) 395–411.
date_created: 2018-12-11T12:07:54Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-06-06T11:45:48Z
day: '01'
doi: 10.1093/genetics/162.1.395
extern: '1'
external_id:
pmid:
- '12242249'
intvolume: ' 162'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462245/
month: '09'
oa: 1
oa_version: None
page: 395 - 411
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1833'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effect of deleterious alleles on adaptation in asexual populations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 162
year: '2002'
...
---
_id: '4349'
abstract:
- lang: eng
text: 'Bayesian inference is becoming a common statistical approach to phylogenetic
estimation because, among other reasons, it allows for rapid analysis of large
data sets with complex evolutionary models. Conveniently, Bayesian phylogenetic
methods use currently available stochastic models of sequence evolution. However,
as with other model-based approaches, the results of Bayesian inference are conditional
on the assumed model of evolution: inadequate models (models that poorly fit the
data) may result in erroneous inferences. In this article, I present a Bayesian
phylogenetic method that evaluates the adequacy of evolutionary models using posterior
predictive distributions. By evaluating a model''s posterior predictive performance,
an adequate model can be selected for a Bayesian phylogenetic study. Although
I present a single test statistic that assesses the overall (global) performance
of a phylogenetic model, a variety of test statistics can be tailored to evaluate
specific features (local performance) of evolutionary models to identify sources
failure. The method presented here, unlike the likelihood-ratio test and parametric
bootstrap, accounts for uncertainty in the phylogeny and model parameters.'
acknowledgement: "This work was supported by grants from the NSF to John Huelsenbeck
(MCB-0075404 and DEB0075406), to whom I am grateful for his support throughout this
project. Also, I would like to express my deep thanks to Andrea Betancourt, John
Huelsenbeck, Kelly Dyer, Rasmus Nielsen, and Frederick Ronquist for taking the time
to read early versions of the\r\nmanuscript. Each and every one of them provided
invaluable comments, that ultimately made the manuscript better. John Huelsenbeck,
Bret Larget, Rasmus Nielsen, Ken Karol, and Andrea Betancourt patiently listened
to me drone on about this project, and offered insightful comments that benefited
this work, and for this they have my deepest gratitude. And finally, I would like
to thank two anonymous reviewers who gave critical attention to the manuscript and
provided valuable comments."
article_processing_charge: No
article_type: original
author:
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Bollback JP. Bayesian model adequacy and choice in phylogenetics. Molecular
Biology and Evolution. 2002;19(7):1171-1180. doi:10.1093/oxfordjournals.molbev.a004175
apa: Bollback, J. P. (2002). Bayesian model adequacy and choice in phylogenetics.
Molecular Biology and Evolution. Oxford University Press. https://doi.org/10.1093/oxfordjournals.molbev.a004175
chicago: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.”
Molecular Biology and Evolution. Oxford University Press, 2002. https://doi.org/10.1093/oxfordjournals.molbev.a004175.
ieee: J. P. Bollback, “Bayesian model adequacy and choice in phylogenetics,” Molecular
Biology and Evolution, vol. 19, no. 7. Oxford University Press, pp. 1171–80,
2002.
ista: Bollback JP. 2002. Bayesian model adequacy and choice in phylogenetics. Molecular
Biology and Evolution. 19(7), 1171–80.
mla: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.”
Molecular Biology and Evolution, vol. 19, no. 7, Oxford University Press,
2002, pp. 1171–80, doi:10.1093/oxfordjournals.molbev.a004175.
short: J.P. Bollback, Molecular Biology and Evolution 19 (2002) 1171–80.
date_created: 2018-12-11T12:08:24Z
date_published: 2002-03-25T00:00:00Z
date_updated: 2023-06-06T09:18:18Z
day: '25'
doi: 10.1093/oxfordjournals.molbev.a004175
extern: '1'
external_id:
pmid:
- '12082136 '
intvolume: ' 19'
issue: '7'
language:
- iso: eng
month: '03'
oa_version: None
page: 1171 - 80
pmid: 1
publication: Molecular Biology and Evolution
publication_identifier:
issn:
- 0737-4038
publication_status: published
publisher: Oxford University Press
publist_id: '1112'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bayesian model adequacy and choice in phylogenetics
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 19
year: '2002'
...
---
_id: '4263'
abstract:
- lang: eng
text: 'We introduce a general recursion for the probability of identity in state
of two individuals sampled from a population subject to mutation, migration, and
random drift in a two-dimensional continuum. The recursion allows for the interactions
induced by density-dependent regulation of the population, which are inevitable
in a continuous population. We give explicit series expansions for large neighbourhood
size and for low mutation rates respectively and investigate the accuracy of the
classical Malécot formula for these general models. When neighbourhood size is
small, this formula does not give the identity even over large scales. However,
for large neighbourhood size, it is an accurate approximation which summarises
the local population structure in terms of three quantities: the effective dispersal
rate, σe; the effective population density, ρe; and a local scale, κ, at which
local interactions become significant. The results are illustrated by simulations.'
acknowledgement: This work was supported by grants from the EPSRC (GR/L10048 and an
advanced fellowship for A.M.E.) and NERC (GR3/11635) and by the Darwin Trust of
Edinburgh. We thank Anja Sturm for her assistance with the project and anonymous
reviewers for helpful comments. This paper is dedicated to Charlotte, A.M.E.’s daughter
born during the gestation of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Frantz
full_name: Depaulis, Frantz
last_name: Depaulis
- first_name: Alison
full_name: Etheridge, Alison
last_name: Etheridge
citation:
ama: Barton NH, Depaulis F, Etheridge A. Neutral evolution in spatially continuous
populations. Theoretical Population Biology. 2002;61(1):31-48. doi:10.1006/tpbi.2001.1557
apa: Barton, N. H., Depaulis, F., & Etheridge, A. (2002). Neutral evolution
in spatially continuous populations. Theoretical Population Biology. Academic
Press. https://doi.org/10.1006/tpbi.2001.1557
chicago: Barton, Nicholas H, Frantz Depaulis, and Alison Etheridge. “Neutral Evolution
in Spatially Continuous Populations.” Theoretical Population Biology. Academic
Press, 2002. https://doi.org/10.1006/tpbi.2001.1557.
ieee: N. H. Barton, F. Depaulis, and A. Etheridge, “Neutral evolution in spatially
continuous populations,” Theoretical Population Biology, vol. 61, no. 1.
Academic Press, pp. 31–48, 2002.
ista: Barton NH, Depaulis F, Etheridge A. 2002. Neutral evolution in spatially continuous
populations. Theoretical Population Biology. 61(1), 31–48.
mla: Barton, Nicholas H., et al. “Neutral Evolution in Spatially Continuous Populations.”
Theoretical Population Biology, vol. 61, no. 1, Academic Press, 2002, pp.
31–48, doi:10.1006/tpbi.2001.1557.
short: N.H. Barton, F. Depaulis, A. Etheridge, Theoretical Population Biology 61
(2002) 31–48.
date_created: 2018-12-11T12:07:55Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-06-06T09:57:49Z
day: '01'
doi: 10.1006/tpbi.2001.1557
extern: '1'
external_id:
pmid:
- '11895381'
intvolume: ' 61'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 31 - 48
pmid: 1
publication: Theoretical Population Biology
publication_identifier:
issn:
- 0040-5809
publication_status: published
publisher: Academic Press
publist_id: '1830'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Neutral evolution in spatially continuous populations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 61
year: '2002'
...
---
_id: '4261'
abstract:
- lang: eng
text: Until recently, it was impracticable to identify the genes that are responsible
for variation in continuous traits, or to directly observe the effects of their
different alleles. Now, the abundance of genetic markers has made it possible
to identify quantitative trait loci (QTL) — the regions of a chromosome or, ideally,
individual sequence variants that are responsible for trait variation. What kind
of QTL do we expect to find and what can our observations of QTL tell us about
how organisms evolve? The key to understanding the evolutionary significance of
QTL is to understand the nature of inherited variation, not in the immediate mechanistic
sense of how genes influence phenotype, but, rather, to know what evolutionary
forces maintain genetic variability.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Peter
full_name: Keightley, Peter
last_name: Keightley
citation:
ama: Barton NH, Keightley P. Understanding quantitative genetic variation. Nature
Reviews Genetics. 2002;3:11-21. doi:10.1038/nrg700
apa: Barton, N. H., & Keightley, P. (2002). Understanding quantitative genetic
variation. Nature Reviews Genetics. Nature Publishing Group. https://doi.org/10.1038/nrg700
chicago: Barton, Nicholas H, and Peter Keightley. “Understanding Quantitative Genetic
Variation.” Nature Reviews Genetics. Nature Publishing Group, 2002. https://doi.org/10.1038/nrg700.
ieee: N. H. Barton and P. Keightley, “Understanding quantitative genetic variation,”
Nature Reviews Genetics, vol. 3. Nature Publishing Group, pp. 11–21, 2002.
ista: Barton NH, Keightley P. 2002. Understanding quantitative genetic variation.
Nature Reviews Genetics. 3, 11–21.
mla: Barton, Nicholas H., and Peter Keightley. “Understanding Quantitative Genetic
Variation.” Nature Reviews Genetics, vol. 3, Nature Publishing Group, 2002,
pp. 11–21, doi:10.1038/nrg700.
short: N.H. Barton, P. Keightley, Nature Reviews Genetics 3 (2002) 11–21.
date_created: 2018-12-11T12:07:55Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-06T10:07:00Z
day: '01'
doi: 10.1038/nrg700
extern: '1'
external_id:
pmid:
- '11823787'
intvolume: ' 3'
language:
- iso: eng
month: '01'
oa_version: None
page: 11 - 21
pmid: 1
publication: Nature Reviews Genetics
publication_identifier:
issn:
- 1471-0056
publication_status: published
publisher: Nature Publishing Group
publist_id: '1831'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Understanding quantitative genetic variation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 3
year: '2002'
...
---
_id: '4347'
abstract:
- lang: eng
text: 'Phylogenetic trees can be rooted by a number of criteria. Here, we introduce
a Bayesian method for inferring the root of a phylogenetic tree by using one of
several criteria: the outgroup, molecular clock, and nonreversible model of DNA
substitution. We perform simulation analyses to examine the relative ability of
these three criteria to correctly identify the root of the tree. The outgroup
and molecular clock criteria were best able to identify the root of the tree,
whereas the nonreversible model was able to identify the root only when the substitution
process was highly nonreversible. We also examined the performance of the criteria
for a tree of four species for which the topology and root position are well supported.
Results of the analyses of these data are consistent with the simulation results.'
article_processing_charge: No
article_type: original
author:
- first_name: John
full_name: Huelsenbeck, John
last_name: Huelsenbeck
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
- first_name: Amy
full_name: Levine, Amy
last_name: Levine
citation:
ama: Huelsenbeck J, Bollback JP, Levine A. Inferring the root of a phylogenetic
tree. Systematic Biology. 2002;51(1):32-43. doi:10.1080/106351502753475862
apa: Huelsenbeck, J., Bollback, J. P., & Levine, A. (2002). Inferring the root
of a phylogenetic tree. Systematic Biology. Oxford University Press. https://doi.org/10.1080/106351502753475862
chicago: Huelsenbeck, John, Jonathan P Bollback, and Amy Levine. “Inferring the
Root of a Phylogenetic Tree.” Systematic Biology. Oxford University Press,
2002. https://doi.org/10.1080/106351502753475862.
ieee: J. Huelsenbeck, J. P. Bollback, and A. Levine, “Inferring the root of a phylogenetic
tree,” Systematic Biology, vol. 51, no. 1. Oxford University Press, pp.
32–43, 2002.
ista: Huelsenbeck J, Bollback JP, Levine A. 2002. Inferring the root of a phylogenetic
tree. Systematic Biology. 51(1), 32–43.
mla: Huelsenbeck, John, et al. “Inferring the Root of a Phylogenetic Tree.” Systematic
Biology, vol. 51, no. 1, Oxford University Press, 2002, pp. 32–43, doi:10.1080/106351502753475862.
short: J. Huelsenbeck, J.P. Bollback, A. Levine, Systematic Biology 51 (2002) 32–43.
date_created: 2018-12-11T12:08:23Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-06-06T09:53:27Z
day: '01'
doi: 10.1080/106351502753475862
extern: '1'
external_id:
pmid:
- '11943091'
intvolume: ' 51'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 32 - 43
pmid: 1
publication: Systematic Biology
publication_identifier:
issn:
- 0039-7989
publication_status: published
publisher: Oxford University Press
publist_id: '1113'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inferring the root of a phylogenetic tree
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 51
year: '2002'
...
---
_id: '4407'
abstract:
- lang: eng
text: 'This paper presents a complete axiomatization of two decidable propositional
real-time linear temporal logics: Event Clock Logic (EventClockTL) and Metric
Interval Temporal Logic with past (MetricIntervalTL). The completeness proof consists
of an effective proof building procedure for EventClockTL. From this result we
obtain a complete axiomatization of MetricIntervalTL by providing axioms translating
MetricIntervalTL formulae into EventClockTL formulae, the two logics being equally
expressive. Our proof is structured to yield axiomatizations also for interesting
fragments of these logics, such as the linear temporal logic of the real numbers
(TLR).'
article_processing_charge: No
article_type: original
author:
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
- first_name: Pierre
full_name: Schobbens, Pierre
last_name: Schobbens
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: Raskin J, Schobbens P, Henzinger TA. Axioms for real-time logics. Theoretical
Computer Science. 2002;274(1-2):151-182. doi:10.1016/S0304-3975(00)00308-X
apa: Raskin, J., Schobbens, P., & Henzinger, T. A. (2002). Axioms for real-time
logics. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/S0304-3975(00)00308-X
chicago: Raskin, Jean, Pierre Schobbens, and Thomas A Henzinger. “Axioms for Real-Time
Logics.” Theoretical Computer Science. Elsevier, 2002. https://doi.org/10.1016/S0304-3975(00)00308-X.
ieee: J. Raskin, P. Schobbens, and T. A. Henzinger, “Axioms for real-time logics,”
Theoretical Computer Science, vol. 274, no. 1–2. Elsevier, pp. 151–182,
2002.
ista: Raskin J, Schobbens P, Henzinger TA. 2002. Axioms for real-time logics. Theoretical
Computer Science. 274(1–2), 151–182.
mla: Raskin, Jean, et al. “Axioms for Real-Time Logics.” Theoretical Computer
Science, vol. 274, no. 1–2, Elsevier, 2002, pp. 151–82, doi:10.1016/S0304-3975(00)00308-X.
short: J. Raskin, P. Schobbens, T.A. Henzinger, Theoretical Computer Science 274
(2002) 151–182.
date_created: 2018-12-11T12:08:42Z
date_published: 2002-03-01T00:00:00Z
date_updated: 2023-06-06T09:10:56Z
day: '01'
doi: 10.1016/S0304-3975(00)00308-X
extern: '1'
intvolume: ' 274'
issue: 1-2
language:
- iso: eng
month: '03'
oa_version: None
page: 151 - 182
publication: Theoretical Computer Science
publication_identifier:
issn:
- 0304-3975
publication_status: published
publisher: Elsevier
publist_id: '324'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Axioms for real-time logics
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 274
year: '2002'
...
---
_id: '4258'
abstract:
- lang: eng
text: We studied the effect of multilocus balancing selection on neutral nucleotide
variability at linked sites by simulating a model where diallelic polymorphisms
are maintained at an arbitrary number of selected loci by means of symmetric overdominance.
Different combinations of alleles define different genetic backgrounds that subdivide
the population and strongly affect variability. Several multilocus fitness regimes
with different degrees of epistasis and gametic disequilibrium are allowed. Analytical
results based on a multilocus extension of the structured coalescent predict that
the expected linked neutral diversity increases exponentially with the number
of selected loci and can become extremely large. Our simulation results show that
although variability increases with the number of genetic backgrounds that are
maintained in the population, it is reduced by random fluctuations in the frequencies
of those backgrounds and does not reach high levels even in very large populations.
We also show that previous results on balancing selection in single-locus systems
do not extend to the multilocus scenario in a straightforward way. Different patterns
of linkage disequilibrium and of the frequency spectrum of neutral mutations are
expected under different degrees of epistasis. Interestingly, the power to detect
balancing selection using deviations from a neutral distribution of allele frequencies
seems to be diminished under the fitness regime that leads to the largest increase
of variability over the neutral case. This and other results are discussed in
the light of data from the Mhc.
acknowledgement: We thank P. Andolfatto, P. Awadalla, B. Charlesworth, D. Charles-
Guillaudeux, T., M. Janer, G. K. S. Wong, T. Spies and D. E. Geraghty, F. Depaulis,
S. Otto, J. Rozas, and three anonymous reviewers for valuable discussion and criticism.
A.N. is grateful to F. Depaulis, whose comments were particularly helpful (and extremely
funny), and to D. Charlesworth, whose ideas made this work readable. This work was
supported by Biotechnology and Biological Sciences Research Council/Engineering
and Physical Sciences Research Council.
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
full_name: Navarro, Arcadio
last_name: Navarro
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Navarro A, Barton NH. The effects of multilocus balancing selection on neutral
variability. Genetics. 2002;161(2):849-863. doi:10.1093/genetics/161.2.849
apa: Navarro, A., & Barton, N. H. (2002). The effects of multilocus balancing
selection on neutral variability. Genetics. Genetics Society of America.
https://doi.org/10.1093/genetics/161.2.849
chicago: Navarro, Arcadio, and Nicholas H Barton. “The Effects of Multilocus Balancing
Selection on Neutral Variability.” Genetics. Genetics Society of America,
2002. https://doi.org/10.1093/genetics/161.2.849.
ieee: A. Navarro and N. H. Barton, “The effects of multilocus balancing selection
on neutral variability,” Genetics, vol. 161, no. 2. Genetics Society of
America, pp. 849–863, 2002.
ista: Navarro A, Barton NH. 2002. The effects of multilocus balancing selection
on neutral variability. Genetics. 161(2), 849–863.
mla: Navarro, Arcadio, and Nicholas H. Barton. “The Effects of Multilocus Balancing
Selection on Neutral Variability.” Genetics, vol. 161, no. 2, Genetics
Society of America, 2002, pp. 849–63, doi:10.1093/genetics/161.2.849.
short: A. Navarro, N.H. Barton, Genetics 161 (2002) 849–863.
date_created: 2018-12-11T12:07:53Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-06T12:02:32Z
day: '01'
doi: 10.1093/genetics/161.2.849
extern: '1'
external_id:
pmid:
- '12072479'
intvolume: ' 161'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462137/
month: '06'
oa: 1
oa_version: Published Version
page: 849 - 863
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1835'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effects of multilocus balancing selection on neutral variability
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 161
year: '2002'
...
---
_id: '4259'
abstract:
- lang: eng
text: 'We extend current multilocus models to describe the effects of migration,
recombination, selection, and nonrandom mating on sets of genes in diploids with
varied modes of inheritance, allowing us to consider the patterns of nuclear and
cytonuclear associations (disequilibria) under various models of migration. We
show the relationship between the multilocus notation recently presented by Kirkpatrick,
Johnson, and Barton (developed from previous work by Barton and Turelli) and the
cytonuclear parameterization of Asmussen, Arnold, and Avise and extend this notation
to describe associations between cytoplasmic elements and multiple nuclear genes.
Under models with sexual symmetry, both nuclear-nuclear and cytonuclear disequilibria
are equivalent. They differ, however, in cases involving some type of sexual asymmetry,
which is then reflected in the asymmetric inheritance of cytoplasmic markers.
An example given is the case of different migration rates in males and females;
simulations using 2, 3, 4, or 5 unlinked autosomal markers with a maternally inherited
cytoplasmic marker illustrate how nuclear-nuclear and cytonuclear associations
can be used to separately estimate female and male migration rates. The general
framework developed here allows us to investigate conditions where associations
between loci with different modes of inheritance are not equivalent and to use
this nonequivalence to test for deviations from simple models of admixture. '
acknowledgement: The authors thank Toby Johnson for his helpful comments on this manuscript.
This work was supported by a National Science Foundation NATO postdoctoral fellowship
and National Science Foundation grants DEB-9813335 and DEB-0108242 to M.E.O.; N.H.B.
gratefully acknowledges the support of the Darwin Trust of Edinburgh and the National
Environmental Research Council.
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Orive, Maria
last_name: Orive
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Orive M, Barton NH. Associations between cytoplasmic and nuclear loci in hybridizing
populations. Genetics. 2002;162(3):1469-1485. doi:10.1093/genetics/162.3.1469
apa: Orive, M., & Barton, N. H. (2002). Associations between cytoplasmic and
nuclear loci in hybridizing populations. Genetics. Genetics Society of
America. https://doi.org/10.1093/genetics/162.3.1469
chicago: Orive, Maria, and Nicholas H Barton. “Associations between Cytoplasmic
and Nuclear Loci in Hybridizing Populations.” Genetics. Genetics Society
of America, 2002. https://doi.org/10.1093/genetics/162.3.1469.
ieee: M. Orive and N. H. Barton, “Associations between cytoplasmic and nuclear loci
in hybridizing populations,” Genetics, vol. 162, no. 3. Genetics Society
of America, pp. 1469–1485, 2002.
ista: Orive M, Barton NH. 2002. Associations between cytoplasmic and nuclear loci
in hybridizing populations. Genetics. 162(3), 1469–1485.
mla: Orive, Maria, and Nicholas H. Barton. “Associations between Cytoplasmic and
Nuclear Loci in Hybridizing Populations.” Genetics, vol. 162, no. 3, Genetics
Society of America, 2002, pp. 1469–85, doi:10.1093/genetics/162.3.1469.
short: M. Orive, N.H. Barton, Genetics 162 (2002) 1469–1485.
date_created: 2018-12-11T12:07:54Z
date_published: 2002-11-01T00:00:00Z
date_updated: 2023-06-06T12:19:54Z
day: '01'
doi: 10.1093/genetics/162.3.1469
extern: '1'
external_id:
pmid:
- '12454089'
intvolume: ' 162'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462324/
month: '11'
oa: 1
oa_version: Published Version
page: 1469 - 1485
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1836'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Associations between cytoplasmic and nuclear loci in hybridizing populations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 162
year: '2002'
...
---
_id: '4209'
abstract:
- lang: eng
text: We have identified widerborst (wdb), a B' regulatory subunit of PP2A, as a
conserved component of planar cell polarization mechanisms in both Drosophila
and in zebrafish. In Drosophila, wdb acts at two steps during planar polarization
of wing epithelial cells. It is required to organize tissue polarity proteins
into proximal and distal cortical domains, thus determining wing hair orientation.
It is also needed to generate the polarized membrane outgrowth that becomes the
wing hair. Widerborst activates the catalytic subunit of PP2A and localizes to
the distal side of a planar microtubule web that lies at the level of apical cell
junctions. This suggests that polarized PP2A activation along the planar microtubule
web is important for planar polarization. In zebrafish, two wdb homologs are required
for convergent extension during gastrulation, supporting the conjecture that Drosophila
planar cell polarization and vertebrate gastrulation movements are regulated by
similar mechanisms.
acknowledgement: We gratefully acknowledge Bianca Habermann for assistance with bioinformatics,
Jens Rietdorf and Arshad Desai for help with deconvolution, and Tadashi Uemura and
Rick Fehon for providing antibodies. Arshad Desai, Christian Dahmann, Tony Hyman
and Elly Tanaka provided helpful comments on the manuscript. Part of this work was
performed at the EMBL in Heidelberg.
article_processing_charge: No
article_type: original
author:
- first_name: Michael
full_name: Hannus, Michael
last_name: Hannus
- first_name: Fabian
full_name: Feiguin, Fabian
last_name: Feiguin
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Suzanne
full_name: Eaton, Suzanne
last_name: Eaton
citation:
ama: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. Planar cell polarization requires
Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development.
2002;129(14):3493-3503. doi:10.1242/dev.129.14.3493
apa: Hannus, M., Feiguin, F., Heisenberg, C.-P. J., & Eaton, S. (2002). Planar
cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase
2A. Development. Company of Biologists. https://doi.org/10.1242/dev.129.14.3493
chicago: Hannus, Michael, Fabian Feiguin, Carl-Philipp J Heisenberg, and Suzanne
Eaton. “Planar Cell Polarization Requires Widerborst, a B′ Regulatory Subunit
of Protein Phosphatase 2A.” Development. Company of Biologists, 2002. https://doi.org/10.1242/dev.129.14.3493.
ieee: M. Hannus, F. Feiguin, C.-P. J. Heisenberg, and S. Eaton, “Planar cell polarization
requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A,” Development,
vol. 129, no. 14. Company of Biologists, pp. 3493–3503, 2002.
ista: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. 2002. Planar cell polarization
requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development.
129(14), 3493–3503.
mla: Hannus, Michael, et al. “Planar Cell Polarization Requires Widerborst, a B′
Regulatory Subunit of Protein Phosphatase 2A.” Development, vol. 129, no.
14, Company of Biologists, 2002, pp. 3493–503, doi:10.1242/dev.129.14.3493.
short: M. Hannus, F. Feiguin, C.-P.J. Heisenberg, S. Eaton, Development 129 (2002)
3493–3503.
date_created: 2018-12-11T12:07:36Z
date_published: 2002-07-15T00:00:00Z
date_updated: 2023-06-06T14:07:49Z
day: '15'
doi: 10.1242/dev.129.14.3493
extern: '1'
external_id:
pmid:
- '12091318'
intvolume: ' 129'
issue: '14'
language:
- iso: eng
month: '07'
oa_version: None
page: 3493 - 3503
pmid: 1
publication: Development
publication_identifier:
issn:
- 0950-1991
publication_status: published
publisher: Company of Biologists
publist_id: '1909'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein
phosphatase 2A
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 129
year: '2002'
...
---
_id: '4207'
abstract:
- lang: eng
text: Vertebrate homologues of the Strabismus/van Gogh (stbm/vang) gene have been
implicated in patterning and morphogenesis during gastrulation. Recent work shows
that stbm/vang is mutated in zebrafish trilobite mutants and that stbm/vang is
required for morphogenesis but not patterning during zebrafish gastrulation.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Heisenberg C-PJ. Wnt signalling: Refocusing on Strabismus. Current Biology.
2002;12(19):R657-R659. doi:10.1016/S0960-9822(02)01160-0'
apa: 'Heisenberg, C.-P. J. (2002). Wnt signalling: Refocusing on Strabismus. Current
Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)01160-0'
chicago: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.”
Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)01160-0.'
ieee: 'C.-P. J. Heisenberg, “Wnt signalling: Refocusing on Strabismus,” Current
Biology, vol. 12, no. 19. Cell Press, pp. R657–R659, 2002.'
ista: 'Heisenberg C-PJ. 2002. Wnt signalling: Refocusing on Strabismus. Current
Biology. 12(19), R657–R659.'
mla: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.” Current
Biology, vol. 12, no. 19, Cell Press, 2002, pp. R657–59, doi:10.1016/S0960-9822(02)01160-0.'
short: C.-P.J. Heisenberg, Current Biology 12 (2002) R657–R659.
date_created: 2018-12-11T12:07:35Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-06-06T15:09:53Z
day: '01'
doi: 10.1016/S0960-9822(02)01160-0
extern: '1'
external_id:
pmid:
- '12361585'
intvolume: ' 12'
issue: '19'
language:
- iso: eng
month: '10'
oa_version: None
page: R657 - R659
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1912'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Wnt signalling: Refocusing on Strabismus'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '4194'
abstract:
- lang: eng
text: Cells at the anterior boundary of the neural plate (ANB) can induce telencephalic
gene expression when transplanted to more posterior regions. Here, we identify
a secreted Frizzled-related Wnt antagonist, Tic, that is expressed in ANB cells
and can cell nonautonomously promote telencephalic gene expression in a concentration-dependent
manner. Moreover, abrogation of Tlc function compromises telencephalic development.
We also identify Wnt8b as a locally acting modulator of regional fate in the anterior
neural plate and a likely target for antagonism by Tic. Finally, we show that
tlc expression is regulated by signals that establish early antero-posterior and
dorso-ventral ectodermal pattern. From these studies, we propose that local antagonism
of Wnt activity within the anterior ectoderm is required to establish the telencephalon.
acknowledgement: We thank many of our colleagues, especially Randy Moon, for providing reagents used
in this study. This study was supported by the Wellcome Trust, MRC, and BBSRC to
S.W.W. and C.H. S.W.W. is a Wellcome Trust Senior Research Fellow.
article_processing_charge: No
article_type: original
author:
- first_name: Corinne
full_name: Houart, Corinne
last_name: Houart
- first_name: Luca
full_name: Caneparo, Luca
last_name: Caneparo
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: K Anukampa
full_name: Barth, K Anukampa
last_name: Barth
- first_name: Masaya
full_name: Take Uchi, Masaya
last_name: Take Uchi
- first_name: Stephen
full_name: Wilson, Stephen
last_name: Wilson
citation:
ama: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. Establishment
of the telencephalon during gastrulation by local antagonism of Wnt signaling.
Neuron. 2002;35(2):255-265. doi:10.1016/S0896-6273(02)00751-1
apa: Houart, C., Caneparo, L., Heisenberg, C.-P. J., Barth, K. A., Take Uchi, M.,
& Wilson, S. (2002). Establishment of the telencephalon during gastrulation
by local antagonism of Wnt signaling. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)00751-1
chicago: Houart, Corinne, Luca Caneparo, Carl-Philipp J Heisenberg, K Anukampa Barth,
Masaya Take Uchi, and Stephen Wilson. “Establishment of the Telencephalon during
Gastrulation by Local Antagonism of Wnt Signaling.” Neuron. Elsevier, 2002.
https://doi.org/10.1016/S0896-6273(02)00751-1.
ieee: C. Houart, L. Caneparo, C.-P. J. Heisenberg, K. A. Barth, M. Take Uchi, and
S. Wilson, “Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling,” Neuron, vol. 35, no. 2. Elsevier, pp. 255–265, 2002.
ista: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. 2002.
Establishment of the telencephalon during gastrulation by local antagonism of
Wnt signaling. Neuron. 35(2), 255–265.
mla: Houart, Corinne, et al. “Establishment of the Telencephalon during Gastrulation
by Local Antagonism of Wnt Signaling.” Neuron, vol. 35, no. 2, Elsevier,
2002, pp. 255–65, doi:10.1016/S0896-6273(02)00751-1.
short: C. Houart, L. Caneparo, C.-P.J. Heisenberg, K.A. Barth, M. Take Uchi, S.
Wilson, Neuron 35 (2002) 255–265.
date_created: 2018-12-11T12:07:30Z
date_published: 2002-07-18T00:00:00Z
date_updated: 2023-06-07T09:43:19Z
day: '18'
doi: 10.1016/S0896-6273(02)00751-1
extern: '1'
external_id:
pmid:
- '12160744'
intvolume: ' 35'
issue: '2'
language:
- iso: eng
month: '07'
oa_version: None
page: 255 - 265
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '1925'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 35
year: '2002'
...
---
_id: '4148'
abstract:
- lang: eng
text: Members of the Wnt family have been implicated in a variety of developmental
processes including axis formation, Patterning of the central nervous system and
tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway
similar to that involved in the establishment of planar cell polarity in Drosophila
regulates convergent extension movements during zebrafish and Xenopus gastrulation.
This finding provides a good starting point to dissect the complex cell biology
and genetic regulation of vertebrate gastrulation movements.
acknowledgement: We would like to thank Steve Wilson for encouraging us to write this
article and for critical comments on this manuscript, and Lila Solnica-Krezel for
communicating results prior to publication. MT is supported by an MRC Career Development
Award, MLC by a Wellcome Trust Fellowship and CPH by an Emmy–Noether–Fellowship
from the DFG.
article_processing_charge: No
article_type: original
author:
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Miguel
full_name: Concha, Miguel
last_name: Concha
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Tada M, Concha M, Heisenberg C-PJ. Non-canonical Wnt signalling and regulation
of gastrulation movements. Seminars in Cell & Developmental Biology.
2002;13(3):251-260. doi:10.1016/S1084-9521(02)00052-6
apa: Tada, M., Concha, M., & Heisenberg, C.-P. J. (2002). Non-canonical Wnt
signalling and regulation of gastrulation movements. Seminars in Cell &
Developmental Biology. Academic Press. https://doi.org/10.1016/S1084-9521(02)00052-6
chicago: Tada, Masazumi, Miguel Concha, and Carl-Philipp J Heisenberg. “Non-Canonical
Wnt Signalling and Regulation of Gastrulation Movements.” Seminars in Cell
& Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084-9521(02)00052-6.
ieee: M. Tada, M. Concha, and C.-P. J. Heisenberg, “Non-canonical Wnt signalling
and regulation of gastrulation movements,” Seminars in Cell & Developmental
Biology, vol. 13, no. 3. Academic Press, pp. 251–260, 2002.
ista: Tada M, Concha M, Heisenberg C-PJ. 2002. Non-canonical Wnt signalling and
regulation of gastrulation movements. Seminars in Cell & Developmental Biology.
13(3), 251–260.
mla: Tada, Masazumi, et al. “Non-Canonical Wnt Signalling and Regulation of Gastrulation
Movements.” Seminars in Cell & Developmental Biology, vol. 13, no.
3, Academic Press, 2002, pp. 251–60, doi:10.1016/S1084-9521(02)00052-6.
short: M. Tada, M. Concha, C.-P.J. Heisenberg, Seminars in Cell & Developmental
Biology 13 (2002) 251–260.
date_created: 2018-12-11T12:07:13Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-07T09:50:14Z
day: '01'
doi: 10.1016/S1084-9521(02)00052-6
extern: '1'
external_id:
pmid:
- '12137734'
intvolume: ' 13'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 251 - 260
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1973'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-canonical Wnt signalling and regulation of gastrulation movements
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4196'
abstract:
- lang: eng
text: During vertebrate gastrulation, large cellular rearrangements lead to the
formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish
offer many genetic and experimental advantages for studying vertebrate gastrulation
movements. For instance, several mutants, including silberblick, knypek and trilobite,
exhibit defects in morphogenesis during gastrulation. The identification of the
genes mutated in these lines together with the analysis of the mutant phenotypes
has provided new insights into the molecular and cellular mechanisms that underlie
vertebrate gastrulation movements.
acknowledgement: We would like to thank Miguel Concha, Will Norton, Tim Geach, Suzanne
Eaton, Kimbo Kotovic, Jenny Geiger and Steve Wilson for critical comments on this
manuscript, and Lila Solnica-Krezel for providing results prior to publication.
C.-P.H. is supported by an Emmy-Noether-Fellowship from the DFG and M.T. by an MRC
Career Development Award.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Zebrafish gastrulation movements: bridging cell and
developmental biology. Seminars in Cell & Developmental Biology. 2002;13(6):471-479.
doi:10.1016/S1084952102001003'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Zebrafish gastrulation movements:
bridging cell and developmental biology. Seminars in Cell & Developmental
Biology. Academic Press. https://doi.org/10.1016/S1084952102001003'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Zebrafish Gastrulation
Movements: Bridging Cell and Developmental Biology.” Seminars in Cell &
Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084952102001003.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Zebrafish gastrulation movements: bridging
cell and developmental biology,” Seminars in Cell & Developmental Biology,
vol. 13, no. 6. Academic Press, pp. 471–479, 2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Zebrafish gastrulation movements: bridging
cell and developmental biology. Seminars in Cell & Developmental Biology.
13(6), 471–479.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Zebrafish Gastrulation Movements:
Bridging Cell and Developmental Biology.” Seminars in Cell & Developmental
Biology, vol. 13, no. 6, Academic Press, 2002, pp. 471–79, doi:10.1016/S1084952102001003.'
short: C.-P.J. Heisenberg, M. Tada, Seminars in Cell & Developmental Biology
13 (2002) 471–479.
date_created: 2018-12-11T12:07:31Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-07T09:28:48Z
day: '01'
doi: 10.1016/S1084952102001003
extern: '1'
external_id:
pmid:
- '12468250'
intvolume: ' 13'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 471 - 479
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1920'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zebrafish gastrulation movements: bridging cell and developmental biology'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4199'
abstract:
- lang: eng
text: Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm)
gene, a key player in planar cell polarity signalling in Drosophila, show that
vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation
where it modulates two distinct Wnt signals.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Wnt signalling: A moving picture emerges from van
gogh. Current Biology. 2002;12(4):R126-R128. doi:10.1016/S0960-9822(02)00704-2'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Wnt signalling: A moving picture
emerges from van gogh. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00704-2'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00704-2.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Wnt signalling: A moving picture emerges
from van gogh,” Current Biology, vol. 12, no. 4. Cell Press, pp. R126–R128,
2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Wnt signalling: A moving picture emerges from
van gogh. Current Biology. 12(4), R126–R128.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology, vol. 12, no. 4, Cell Press,
2002, pp. R126–28, doi:10.1016/S0960-9822(02)00704-2.'
short: C.-P.J. Heisenberg, M. Tada, Current Biology 12 (2002) R126–R128.
date_created: 2018-12-11T12:07:32Z
date_published: 2002-02-19T00:00:00Z
date_updated: 2023-06-07T08:54:35Z
day: '19'
doi: 10.1016/S0960-9822(02)00704-2
extern: '1'
external_id:
pmid:
- '11864583'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: R126 - R128
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1919'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Wnt signalling: A moving picture emerges from van gogh'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '4139'
abstract:
- lang: eng
text: Pilot studies in England by Stopka and Macdonald revealed that allogrooming
in the Old World wood mouse, Apodemus sylvaticus, is a commodity that males can
trade for reproductive benefits with females. This study, which used a combination
of field study and observations in experimental enclosures, revealed that specific
experimental conditions such as group-size and sex-ratio manipulations have a
significant effect on the pattern of allogrooming exchanged between individuals.
Furthermore, females from the Czech population were more likely to associate with
each other as revealed by the clustering of activity centers of females (i.e.,
as opposed to almost exclusive ranges in English populations), and also by the
higher intensity of allogrooming exchanged between females (i.e., virtually lacking
in the previous experiment with English mice). Therefore, geographic variation
and specific social conditions seem to be important driving factors for allogrooming
behavior. Together with changes in overall grooming patterns, allogrooming between
males and females remained invariably asymmetrical over all four experimental
groups (i.e., two conditions for each sex) in that males provided more allogrooming
to females than they received from them.
article_processing_charge: No
article_type: original
author:
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: P.
full_name: Stopka, P.
last_name: Stopka
citation:
ama: Polechova J, Stopka P. Geometry of social relationships in the Old World wood
mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 2002;80(8):1383-1388.
doi:10.1139/z02-128
apa: Polechova, J., & Stopka, P. (2002). Geometry of social relationships in
the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology.
NRC Research Press. https://doi.org/10.1139/z02-128
chicago: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the
Old World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology.
NRC Research Press, 2002. https://doi.org/10.1139/z02-128.
ieee: J. Polechova and P. Stopka, “Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus,” Canadian Journal of Zoology, vol. 80,
no. 8. NRC Research Press, pp. 1383–1388, 2002.
ista: Polechova J, Stopka P. 2002. Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 80(8), 1383–1388.
mla: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the Old
World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology, vol.
80, no. 8, NRC Research Press, 2002, pp. 1383–88, doi:10.1139/z02-128.
short: J. Polechova, P. Stopka, Canadian Journal of Zoology 80 (2002) 1383–1388.
date_created: 2018-12-11T12:07:10Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T12:53:35Z
day: '01'
doi: 10.1139/z02-128
extern: '1'
intvolume: ' 80'
issue: '8'
language:
- iso: eng
month: '01'
oa_version: None
page: 1383 - 1388
publication: Canadian Journal of Zoology
publication_identifier:
issn:
- 0008-4301
publication_status: published
publisher: NRC Research Press
publist_id: '1981'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 80
year: '2002'
...
---
_id: '4003'
abstract:
- lang: eng
text: The writhing number measures the global geometry of a closed space curve or
knot. We show that this measure is related to the average winding number of its
Gauss map. Using this relationship, we give an algorithm for computing the writhing
number for a polygonal knot with n edges in time roughly proportional to n(1.6).
We also implement a different, simple algorithm and provide experimental evidence
for its practical efficiency.
acknowledgement: NSF under grants CCR-00-86013 and EIA-9972879, NSF under grant CCR-97-12088.
article_processing_charge: No
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Yusu
full_name: Wang, Yusu
last_name: Wang
citation:
ama: 'Agarwal P, Edelsbrunner H, Wang Y. Computing the writhing number of a polygonal
knot. In: Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms.
SIAM; 2002:791-799.'
apa: 'Agarwal, P., Edelsbrunner, H., & Wang, Y. (2002). Computing the writhing
number of a polygonal knot. In Proceedings of the 13th annual ACM-SIAM symposium
on Discrete algorithms (pp. 791–799). San Francisco, CA, USA: SIAM.'
chicago: Agarwal, Pankaj, Herbert Edelsbrunner, and Yusu Wang. “Computing the Writhing
Number of a Polygonal Knot.” In Proceedings of the 13th Annual ACM-SIAM Symposium
on Discrete Algorithms, 791–99. SIAM, 2002.
ieee: P. Agarwal, H. Edelsbrunner, and Y. Wang, “Computing the writhing number of
a polygonal knot,” in Proceedings of the 13th annual ACM-SIAM symposium on
Discrete algorithms, San Francisco, CA, USA, 2002, pp. 791–799.
ista: 'Agarwal P, Edelsbrunner H, Wang Y. 2002. Computing the writhing number of
a polygonal knot. Proceedings of the 13th annual ACM-SIAM symposium on Discrete
algorithms. SODA: Symposium on Discrete Algorithms, 791–799.'
mla: Agarwal, Pankaj, et al. “Computing the Writhing Number of a Polygonal Knot.”
Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms,
SIAM, 2002, pp. 791–99.
short: P. Agarwal, H. Edelsbrunner, Y. Wang, in:, Proceedings of the 13th Annual
ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2002, pp. 791–799.
conference:
end_date: 2002-01-08
location: San Francisco, CA, USA
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2002-01-06
date_created: 2018-12-11T12:06:23Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T13:50:04Z
day: '01'
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://dl.acm.org/doi/10.5555/545381.545485
month: '01'
oa_version: None
page: 791 - 799
publication: Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms
publication_identifier:
isbn:
- '9780898715132'
publication_status: published
publisher: SIAM
publist_id: '2125'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Computing the writhing number of a polygonal knot
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '3995'
abstract:
- lang: eng
text: This article is a survey of research areas in which motion plays a pivotal
role. The aim of the article is to review current approaches to modeling motion
together with related data structures and algorithms, and to summarize the challenges
that lie ahead in producing a more unified theory of motion representation that
would be useful across several disciplines.
acknowledgement: "This article is based on the report of the Workshop on Algorithmic
Issues in Modeling Motion, sponsored\r\nby an NSF grant CCR-00-83-033 and an Army
Research Office grant DAAD 19-00-1-0478, held on August 6\r\nand 7, 2000 at Duke
University, Durham, NC."
article_processing_charge: No
article_type: original
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Leonidas
full_name: Guibas, Leonidas
last_name: Guibas
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Jeff
full_name: Erickson, Jeff
last_name: Erickson
- first_name: Michael
full_name: Isard, Michael
last_name: Isard
- first_name: Sariel
full_name: Har Peled, Sariel
last_name: Har Peled
- first_name: John
full_name: Hershberger, John
last_name: Hershberger
- first_name: Christian
full_name: Jensen, Christian
last_name: Jensen
- first_name: Lydia
full_name: Kavraki, Lydia
last_name: Kavraki
- first_name: Patrice
full_name: Koehl, Patrice
last_name: Koehl
- first_name: Ming
full_name: Lin, Ming
last_name: Lin
- first_name: Dinesh
full_name: Manocha, Dinesh
last_name: Manocha
- first_name: Dimitris
full_name: Metaxas, Dimitris
last_name: Metaxas
- first_name: Brian
full_name: Mirtich, Brian
last_name: Mirtich
- first_name: David
full_name: Mount, David
last_name: Mount
- first_name: Sankara
full_name: Muthukrishnan, Sankara
last_name: Muthukrishnan
- first_name: Dinesh
full_name: Pai, Dinesh
last_name: Pai
- first_name: Elisha
full_name: Sacks, Elisha
last_name: Sacks
- first_name: Jack
full_name: Snoeyink, Jack
last_name: Snoeyink
- first_name: Subhash
full_name: Suri, Subhash
last_name: Suri
- first_name: Ouri
full_name: Wolefson, Ouri
last_name: Wolefson
citation:
ama: Agarwal P, Guibas L, Edelsbrunner H, et al. Algorithmic issues in modeling
motion. ACM Computing Surveys. 2002;34(4):550-572. doi:10.1145/592642.592647
apa: Agarwal, P., Guibas, L., Edelsbrunner, H., Erickson, J., Isard, M., Har Peled,
S., … Wolefson, O. (2002). Algorithmic issues in modeling motion. ACM Computing
Surveys. ACM. https://doi.org/10.1145/592642.592647
chicago: Agarwal, Pankaj, Leonidas Guibas, Herbert Edelsbrunner, Jeff Erickson,
Michael Isard, Sariel Har Peled, John Hershberger, et al. “Algorithmic Issues
in Modeling Motion.” ACM Computing Surveys. ACM, 2002. https://doi.org/10.1145/592642.592647.
ieee: P. Agarwal et al., “Algorithmic issues in modeling motion,” ACM
Computing Surveys, vol. 34, no. 4. ACM, pp. 550–572, 2002.
ista: Agarwal P, Guibas L, Edelsbrunner H, Erickson J, Isard M, Har Peled S, Hershberger
J, Jensen C, Kavraki L, Koehl P, Lin M, Manocha D, Metaxas D, Mirtich B, Mount
D, Muthukrishnan S, Pai D, Sacks E, Snoeyink J, Suri S, Wolefson O. 2002. Algorithmic
issues in modeling motion. ACM Computing Surveys. 34(4), 550–572.
mla: Agarwal, Pankaj, et al. “Algorithmic Issues in Modeling Motion.” ACM Computing
Surveys, vol. 34, no. 4, ACM, 2002, pp. 550–72, doi:10.1145/592642.592647.
short: P. Agarwal, L. Guibas, H. Edelsbrunner, J. Erickson, M. Isard, S. Har Peled,
J. Hershberger, C. Jensen, L. Kavraki, P. Koehl, M. Lin, D. Manocha, D. Metaxas,
B. Mirtich, D. Mount, S. Muthukrishnan, D. Pai, E. Sacks, J. Snoeyink, S. Suri,
O. Wolefson, ACM Computing Surveys 34 (2002) 550–572.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:34:25Z
day: '01'
doi: 10.1145/592642.592647
extern: '1'
intvolume: ' 34'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 550 - 572
publication: ACM Computing Surveys
publication_identifier:
issn:
- 0360-0300
publication_status: published
publisher: ACM
publist_id: '2129'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Algorithmic issues in modeling motion
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 34
year: '2002'
...
---
_id: '4000'
abstract:
- lang: eng
text: We present fast implementations of a hybrid algorithm for reporting box and
cube intersections. Our algorithm initially takes a divide-and-conquer approach
and switches to simpler algorithms for low numbers of boxes. We use our implementations
as engines to solve problems about geometric primitives. We look at two such problems
in the category of quality analysis of surface triangulations.
acknowledgement: Center for Simulation of Advanced Rockets funded by the U.S. Department
of Energy under Subcontract B341494, NSF under grant CCR-96-19542 and ARO under
grant DAAG55-98-1-0177.
article_processing_charge: No
article_type: original
author:
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: Zomorodian A, Edelsbrunner H. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 2002;12(1-2):143-172.
doi:10.1142/S0218195902000785
apa: Zomorodian, A., & Edelsbrunner, H. (2002). Fast software for box intersections.
International Journal of Computational Geometry and Applications. World
Scientific Publishing. https://doi.org/10.1142/S0218195902000785
chicago: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications. World
Scientific Publishing, 2002. https://doi.org/10.1142/S0218195902000785.
ieee: A. Zomorodian and H. Edelsbrunner, “Fast software for box intersections,”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2. World Scientific Publishing, pp. 143–172, 2002.
ista: Zomorodian A, Edelsbrunner H. 2002. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 12(1–2), 143–172.
mla: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2, World Scientific Publishing, 2002, pp. 143–72, doi:10.1142/S0218195902000785.
short: A. Zomorodian, H. Edelsbrunner, International Journal of Computational Geometry
and Applications 12 (2002) 143–172.
date_created: 2018-12-11T12:06:22Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T11:20:09Z
day: '01'
doi: 10.1142/S0218195902000785
extern: '1'
intvolume: ' 12'
issue: 1-2
language:
- iso: eng
month: '01'
oa_version: None
page: 143 - 172
publication: International Journal of Computational Geometry and Applications
publication_identifier:
issn:
- 0218-1959
publication_status: published
publisher: World Scientific Publishing
publist_id: '2128'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast software for box intersections
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3998'
abstract:
- lang: eng
text: We present results on a two-step improvement of mesh quality in three-dimensional
Delaunay triangulations. The first step refines the triangulation by inserting
sinks and eliminates tetrahedra with large circumradius over shortest edge length
ratio. The second step assigns weights to the vertices to eliminate slivers. Our
experimental findings provide evidence for the practical effectiveness of sliver
exudation.
acknowledgement: NSF under grants CCR-97-12088 and DMS 98-73945, NSF under grands
EIA-9972879 and CCR-00-86013 and by ARO under grant DAAG55-98-1- 0177.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Damrong
full_name: Guoy, Damrong
last_name: Guoy
citation:
ama: Edelsbrunner H, Guoy D. An experimental study of sliver exudation. Engineering
with Computers. 2002;18(3):229-240. doi:10.1007/s003660200020
apa: Edelsbrunner, H., & Guoy, D. (2002). An experimental study of sliver exudation.
Engineering with Computers. Springer. https://doi.org/10.1007/s003660200020
chicago: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver
Exudation.” Engineering with Computers. Springer, 2002. https://doi.org/10.1007/s003660200020.
ieee: H. Edelsbrunner and D. Guoy, “An experimental study of sliver exudation,”
Engineering with Computers, vol. 18, no. 3. Springer, pp. 229–240, 2002.
ista: Edelsbrunner H, Guoy D. 2002. An experimental study of sliver exudation. Engineering
with Computers. 18(3), 229–240.
mla: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver Exudation.”
Engineering with Computers, vol. 18, no. 3, Springer, 2002, pp. 229–40,
doi:10.1007/s003660200020.
short: H. Edelsbrunner, D. Guoy, Engineering with Computers 18 (2002) 229–240.
date_created: 2018-12-11T12:06:21Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-06-13T11:14:44Z
day: '01'
doi: 10.1007/s003660200020
extern: '1'
intvolume: ' 18'
issue: '3'
language:
- iso: eng
month: '10'
oa_version: None
page: 229 - 240
publication: Engineering with Computers
publication_identifier:
issn:
- 0177-0667
publication_status: published
publisher: Springer
publist_id: '2126'
quality_controlled: '1'
scopus_import: '1'
status: public
title: An experimental study of sliver exudation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 18
year: '2002'
...
---
_id: '3802'
abstract:
- lang: eng
text: The presynaptic Ca2+ signal is a key determinant of transmitter release at
chemical synapses. In cortical synaptic terminals, however, little is known about
the kinetic properties of the presynaptic Ca2+ channels. To investigate the timing
and magnitude of the presynaptic Ca2+ inflow, we performed whole-cell patch-clamp
recordings from mossy fiber boutons (MFBs) in rat hippocampus. MFBs showed large
high-voltage-activated Ca(2+) currents, with a maximal amplitude of approximately
100 pA at a membrane potential of 0 mV. Both activation and deactivation were
fast, with time constants in the submillisecond range at a temperature of approximately
23 degrees C. An MFB action potential (AP) applied as a voltage-clamp command
evoked a transient Ca2+ current with an average amplitude of approximately 170
pA and a half-duration of 580 microsec. A prepulse to +40 mV had only minimal
effects on the AP-evoked Ca2+ current, indicating that presynaptic APs open the
voltage-gated Ca2+ channels very effectively. On the basis of the experimental
data, we developed a kinetic model with four closed states and one open state,
linked by voltage-dependent rate constants. Simulations of the Ca2+ current could
reproduce the experimental data, including the large amplitude and rapid time
course of the current evoked by MFB APs. Furthermore, the simulations indicate
that the shape of the presynaptic AP and the gating kinetics of the Ca2+ channels
are tuned to produce a maximal Ca2+ influx during a minimal period of time. The
precise timing and high efficacy of Ca2+ channel activation at this cortical glutamatergic
synapse may be important for synchronous transmitter release and temporal information
processing.
acknowledgement: J.B. was supported by grants from the Deutsche Forschungsgemeinschaft
(Bi 642/1-2 and SFB 505/C9). We thank Dr. U. Kraushaar, Dr. S. Hefft, and C. Schmidt-Hieber
for critically reading this manuscript, F. Heyde for secretarial help, and A. Blomenkamp
and K. Winterhalter for technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bischofberger J, Geiger J, Jonas PM. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience.
2002;22(24):10593-10602. doi:10.1523/JNEUROSCI.22-24-10593.2002
apa: Bischofberger, J., Geiger, J., & Jonas, P. M. (2002). Timing and efficacy
of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of
Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002
chicago: Bischofberger, Josef, Jörg Geiger, and Peter M Jonas. “Timing and Efficacy
of Ca(2+) Channel Activation in Hippocampal Mossy Fiber Boutons.” Journal of
Neuroscience. Society for Neuroscience, 2002. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002.
ieee: J. Bischofberger, J. Geiger, and P. M. Jonas, “Timing and efficacy of Ca(2+)
channel activation in hippocampal mossy fiber boutons,” Journal of Neuroscience,
vol. 22, no. 24. Society for Neuroscience, pp. 10593–10602, 2002.
ista: Bischofberger J, Geiger J, Jonas PM. 2002. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 22(24),
10593–10602.
mla: Bischofberger, Josef, et al. “Timing and Efficacy of Ca(2+) Channel Activation
in Hippocampal Mossy Fiber Boutons.” Journal of Neuroscience, vol. 22,
no. 24, Society for Neuroscience, 2002, pp. 10593–602, doi:10.1523/JNEUROSCI.22-24-10593.2002.
short: J. Bischofberger, J. Geiger, P.M. Jonas, Journal of Neuroscience 22 (2002)
10593–10602.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T13:19:45Z
day: '01'
doi: 10.1523/JNEUROSCI.22-24-10593.2002
extern: '1'
external_id:
pmid:
- '12486151'
intvolume: ' 22'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758411/
month: '12'
oa: 1
oa_version: Published Version
page: 10593 - 10602
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2407'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber
boutons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 22
year: '2002'
...
---
_id: '3919'
abstract:
- lang: eng
text: Hamilton's concept of local mate competition (LMC) is the standard model to
explain female-biased sex ratios in solitary Hymenoptera. In social Hymenoptera,
however, LMC has remained controversial, mainly because manipulation of sex allocation
by workers in response to relatedness asymmetries is an additional powerful mechanism
of female bias. Furthermore, the predominant mating systems in the social insects
are thought to make LMC unlikely. Nevertheless, several species exist in which
dispersal of males is limited and mating occurs in the nest. Some of these species,
such as the ant Cardiocondyla obscurior, have evolved dimorphic males, with one
morph being specialized for dispersal and the other for fighting with nest-mate
males over access to females. Such life history, combining sociality and alternative
reproductive tactics in males, provides a unique opportunity to test the power
of LMC as a selective force leading to female-biased sex ratios in social Hymenoptera.
We show that, in concordance with LMC predictions, an experimental increase in
queen number leads to a shift in sex allocation in favour of non-dispersing males,
but does not influence the proportion of disperser males. Furthermore, we can
assign this change in sex allocation at the colony level to the queens and rule
out worker manipulation.
acknowledgement: 'We thank A. F. G. Bourke, J. J. Boomsma, S. Foitzik, M. Sixt,C.
Anderson and C. Schubart for improving the manuscript, and E. Sixt for ant illustrations (figure 2). This study was
funded by the DFG (Deutsche Forschungsgemeinschaft: He1623/7-2).'
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Heinze J. Adaptive production of fighter males: queens of the ant
Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 2002;269(1489):417-422.
doi:10.1098/rspb.2001.1892'
apa: 'Cremer, S., & Heinze, J. (2002). Adaptive production of fighter males:
queens of the ant Cardiocondyla adjust the sex ratio under local mate competition.
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The. https://doi.org/10.1098/rspb.2001.1892'
chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The, 2002. https://doi.org/10.1098/rspb.2001.1892.'
ieee: 'S. Cremer and J. Heinze, “Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition,” Proceedings
of the Royal Society of London Series B Biological Sciences, vol. 269, no.
1489. Royal Society, The, pp. 417–422, 2002.'
ista: 'Cremer S, Heinze J. 2002. Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 269(1489), 417–422.'
mla: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences,
vol. 269, no. 1489, Royal Society, The, 2002, pp. 417–22, doi:10.1098/rspb.2001.1892.'
short: S. Cremer, J. Heinze, Proceedings of the Royal Society of London Series B
Biological Sciences 269 (2002) 417–422.
date_created: 2018-12-11T12:05:53Z
date_published: 2002-02-22T00:00:00Z
date_updated: 2023-06-13T11:52:17Z
day: '22'
doi: 10.1098/rspb.2001.1892
extern: '1'
external_id:
pmid:
- '11886631'
intvolume: ' 269'
issue: '1489'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1690910/
month: '02'
oa: 1
oa_version: None
page: 417 - 422
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_identifier:
issn:
- 0962-8452
publication_status: published
publisher: Royal Society, The
publist_id: '2231'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Adaptive production of fighter males: queens of the ant Cardiocondyla adjust
the sex ratio under local mate competition'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 269
year: '2002'
...
---
_id: '3924'
abstract:
- lang: eng
text: 'Males of the ant Cardiocondyla show a dispersal dimorphism of a winged and
wingless morph. The loss of flight has lead to morphological reductions in the
wingless (ergatoid) males and also affected body size, eye size and pigmentation.
As ergatoid males mate exclusively inside the maternal nest, they underlie increased
male-male competition and therefore have also evolved additional changes in behaviour
and physiology: in contrast to winged males, ergatoid males are highly aggressive
towards each other and their spermatogenesis is prolonged compared to all other
hymenopteran males. In addition to these two male morphs, we found males with
an intermediate appearance. These "intermorphic" males provide a transitional
stage between normal males in most investigated morphological and physiological
parameters. As they are produced extremely rarely and only in colonies that switch
between pure ergatoid to mixed male production, we argue that they likely represent
a developmental mistake. Parallels between the determination of male morphs and
female castes (queen-worker dimorphism and worker polymorphism) might help to
understand how the large potential of phenotypic plasticity in both sexes of social
insects is realised during development.'
acknowledgement: We would like to thank S. Karpeles for histological analysis of the
winged males and S. Buchhauser for help with the photographs. This study was funded
by the DFG (grant He1623/12–1).
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Birgit
full_name: Lautenschläger, Birgit
last_name: Lautenschläger
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Cremer S, Lautenschläger B, Heinze J. A transitional stage between the ergatoid
and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
2002;49(3):221-228. doi:10.1007/s00040-002-8305-z
apa: Cremer, S., Lautenschläger, B., & Heinze, J. (2002). A transitional stage
between the ergatoid and winged male morph in the ant Cardiocondyla obscurior.
Insectes Sociaux. Springer. https://doi.org/10.1007/s00040-002-8305-z
chicago: Cremer, Sylvia, Birgit Lautenschläger, and Jürgen Heinze. “A Transitional
Stage between the Ergatoid and Winged Male Morph in the Ant Cardiocondyla Obscurior.”
Insectes Sociaux. Springer, 2002. https://doi.org/10.1007/s00040-002-8305-z.
ieee: S. Cremer, B. Lautenschläger, and J. Heinze, “A transitional stage between
the ergatoid and winged male morph in the ant Cardiocondyla obscurior,” Insectes
Sociaux, vol. 49, no. 3. Springer, pp. 221–228, 2002.
ista: Cremer S, Lautenschläger B, Heinze J. 2002. A transitional stage between the
ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
49(3), 221–228.
mla: Cremer, Sylvia, et al. “A Transitional Stage between the Ergatoid and Winged
Male Morph in the Ant Cardiocondyla Obscurior.” Insectes Sociaux, vol.
49, no. 3, Springer, 2002, pp. 221–28, doi:10.1007/s00040-002-8305-z.
short: S. Cremer, B. Lautenschläger, J. Heinze, Insectes Sociaux 49 (2002) 221–228.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-04-05T00:00:00Z
date_updated: 2023-06-13T11:44:08Z
day: '05'
doi: 10.1007/s00040-002-8305-z
extern: '1'
intvolume: ' 49'
issue: '3'
language:
- iso: eng
month: '04'
oa_version: None
page: 221 - 228
publication: Insectes Sociaux
publication_identifier:
issn:
- 0020-1812
publication_status: published
publisher: Springer
publist_id: '2229'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A transitional stage between the ergatoid and winged male morph in the ant
Cardiocondyla obscurior
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 49
year: '2002'
...
---
_id: '3925'
abstract:
- lang: eng
text: Males of the tropical ant Cardiocondyla obscurior are either wingless and
aggressive or winged and docile, and both compete for access to virgin queens
in the nest1, 2. Although the fighter males (ergatoids) attack and kill other
ergatoids, they tolerate and even attempt to mate with their winged rivals. Here
we show that the winged males avoid the aggression of wingless males by mimicking
the chemical bouquet of virgin queens, but that their mating success is not reduced
as a result. This example of female mimicry by vigorous males is surprising, as
in other species it is typically used as a protective strategy by weaker males,
and may explain the coexistence and equal mating success of two male morphs.
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Sledge M, Heinze J. Chemical mimicry: Male ants disguised by the
queen’s bouquet. Nature. 2002;419:897-897. doi:10.1038/419897a'
apa: 'Cremer, S., Sledge, M., & Heinze, J. (2002). Chemical mimicry: Male ants
disguised by the queen’s bouquet. Nature. Nature Publishing Group. https://doi.org/10.1038/419897a'
chicago: 'Cremer, Sylvia, Matthew Sledge, and Jürgen Heinze. “Chemical Mimicry:
Male Ants Disguised by the Queen’s Bouquet.” Nature. Nature Publishing
Group, 2002. https://doi.org/10.1038/419897a.'
ieee: 'S. Cremer, M. Sledge, and J. Heinze, “Chemical mimicry: Male ants disguised
by the queen’s bouquet,” Nature, vol. 419. Nature Publishing Group, pp.
897–897, 2002.'
ista: 'Cremer S, Sledge M, Heinze J. 2002. Chemical mimicry: Male ants disguised
by the queen’s bouquet. Nature. 419, 897–897.'
mla: 'Cremer, Sylvia, et al. “Chemical Mimicry: Male Ants Disguised by the Queen’s
Bouquet.” Nature, vol. 419, Nature Publishing Group, 2002, pp. 897–897,
doi:10.1038/419897a.'
short: S. Cremer, M. Sledge, J. Heinze, Nature 419 (2002) 897–897.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-10-31T00:00:00Z
date_updated: 2023-06-13T11:47:19Z
day: '31'
doi: 10.1038/419897a
extern: '1'
external_id:
pmid:
- '12410300'
intvolume: ' 419'
language:
- iso: eng
month: '10'
oa_version: None
page: 897 - 897
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '2230'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Chemical mimicry: Male ants disguised by the queen''s bouquet'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 419
year: '2002'
...
---
_id: '3996'
abstract:
- lang: eng
text: We formalize a notion of topological simplification within the framework of
a filtration, which is the history of a growing complex. We classify a topological
change that happens during growth as either a feature or noise depending on its
lifetime or persistence within the filtration. We give fast algorithms for computing
persistence and experimental evidence for their speed and utility.
acknowledgement: "We thank Jeff Erickson and John Harer for helpful discussions during
early stages of this\r\npaper. We also thank Daniel Huson for the zeolite dataset
Z, Thomas LaBean for the DNA\r\ndataset D, and the Stanford Graphics Lab for the
Buddha dataset S. To generate the bone\r\ndataset B, we sampled an iso-surface generated
by Dominique Attali. The volume data\r\nTopological Persistence and Simplification
533 was provided by Francoise Peyrin from CNRS CREATIS in Lyon and was issued from
¸ Synchrotron Radiation Microtomography from the ID19 beamline at ESRF in Grenoble.\r\nWe
generated Fig. 17 using the Protein Explorer [6]."
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: David
full_name: Letscher, David
last_name: Letscher
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
citation:
ama: Edelsbrunner H, Letscher D, Zomorodian A. Topological persistence and simplification.
Discrete & Computational Geometry. 2002;28(4):511-533. doi:10.1007/s00454-002-2885-2
apa: Edelsbrunner, H., Letscher, D., & Zomorodian, A. (2002). Topological persistence
and simplification. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-002-2885-2
chicago: Edelsbrunner, Herbert, David Letscher, and Afra Zomorodian. “Topological
Persistence and Simplification.” Discrete & Computational Geometry.
Springer, 2002. https://doi.org/10.1007/s00454-002-2885-2.
ieee: H. Edelsbrunner, D. Letscher, and A. Zomorodian, “Topological persistence
and simplification,” Discrete & Computational Geometry, vol. 28, no.
4. Springer, pp. 511–533, 2002.
ista: Edelsbrunner H, Letscher D, Zomorodian A. 2002. Topological persistence and
simplification. Discrete & Computational Geometry. 28(4), 511–533.
mla: Edelsbrunner, Herbert, et al. “Topological Persistence and Simplification.”
Discrete & Computational Geometry, vol. 28, no. 4, Springer, 2002,
pp. 511–33, doi:10.1007/s00454-002-2885-2.
short: H. Edelsbrunner, D. Letscher, A. Zomorodian, Discrete & Computational
Geometry 28 (2002) 511–533.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:41:19Z
day: '01'
doi: 10.1007/s00454-002-2885-2
extern: '1'
intvolume: ' 28'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 511 - 533
publication: Discrete & Computational Geometry
publication_identifier:
issn:
- 0179-5376
publication_status: published
publisher: Springer
publist_id: '2130'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Topological persistence and simplification
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 28
year: '2002'
...
---
_id: '3920'
abstract:
- lang: eng
text: A particular Solid Injector needle, suitable for GC-MS analyses of small specimens,
is described together with its application in a study on ants.
acknowledgement: "We thank Giancarlo Bucelli and Gloriano Moneti (Centro Interdipartimentale\r\ndi
Spettrometria di Massa, Università di Firenze) for their help. Funding was\r\nprovided
by the MURST “60%” and Italian CNR “40%” funds, as well as through\r\nthe research
network “Social evolution” of the Universities of Aarhus, Firenze,\r\nKeele, Sheffield,
Uppsala, Würzburg and the ETH of Zürich financed by the\r\nEuropean commission via
the Training and Mobility of Researchers (TMR)\r\nprogramme. "
article_processing_charge: No
article_type: original
author:
- first_name: Stefano
full_name: Turillazzi, Stefano
last_name: Turillazzi
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Turillazzi S, Sledge M, Cremer S, Heinze J. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 2002;4:169-175.
apa: Turillazzi, S., Sledge, M., Cremer, S., & Heinze, J. (2002). A method for
analysing small-size specimens in GC-MS. Insect Social Life. Elsevier.
chicago: Turillazzi, Stefano, Matthew Sledge, Sylvia Cremer, and Jürgen Heinze.
“A Method for Analysing Small-Size Specimens in GC-MS.” Insect Social Life.
Elsevier, 2002.
ieee: S. Turillazzi, M. Sledge, S. Cremer, and J. Heinze, “A method for analysing
small-size specimens in GC-MS,” Insect Social Life, vol. 4. Elsevier, pp.
169–175, 2002.
ista: Turillazzi S, Sledge M, Cremer S, Heinze J. 2002. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 4, 169–175.
mla: Turillazzi, Stefano, et al. “A Method for Analysing Small-Size Specimens in
GC-MS.” Insect Social Life, vol. 4, Elsevier, 2002, pp. 169–75.
short: S. Turillazzi, M. Sledge, S. Cremer, J. Heinze, Insect Social Life 4 (2002)
169–175.
date_created: 2018-12-11T12:05:54Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T12:57:06Z
day: '01'
extern: '1'
intvolume: ' 4'
language:
- iso: eng
month: '01'
oa_version: None
page: 169 - 175
publication: Insect Social Life
publication_status: published
publisher: Elsevier
publist_id: '2232'
quality_controlled: '1'
status: public
title: A method for analysing small-size specimens in GC-MS
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 4
year: '2002'
...
---
_id: '3800'
abstract:
- lang: eng
text: Networks of GABAergic interneurons are of critical importance for the generation
of gamma frequency oscillations in the brain. To examine the underlying synaptic
mechanisms, we made paired recordings from "basket cells" (BCs) in different
subfields of hippocampal slices, using transgenic mice that express enhanced green
fluorescent protein (EGFP) under the control of the parvalbumin promoter. Unitary
inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time
course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8
ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively
(33-34 degrees C). The decay of unitary IPSCs at BC-BC synapses was significantly
faster than that at BC-principal cell synapses, indicating target cell-specific
differences in IPSC kinetics. In addition, electrical coupling was found in a
subset of BC-BC pairs. To examine whether an interneuron network with fast inhibitory
synapses can act as a gamma frequency oscillator, we developed an interneuron
network model based on experimentally determined properties. In comparison to
previous interneuron network models, our model was able to generate oscillatory
activity with higher coherence over a broad range of frequencies (20-110 Hz).
In this model, high coherence and flexibility in frequency control emerge from
the combination of synaptic properties, network structure, and electrical coupling.
acknowledgement: We thank Drs. J. Bischofberger, M. Heckmann, and R. Traub for critically
reading the manuscript. This work was supported by Deutsche Forschungsgemeinschaft
Grants SFB 505/C5 (to P.J.) and SFB 505/C6 (to M.F. and P.J.), Human Frontiers Science
Program Organization Grant RG0017/1998-B (to P.J.), and grants from the Alexander-von-Humboldt
Foundation (to P.J. and M.F.), the Schilling Foundation (to H.M.), and Novartis
(to H.M.).
article_processing_charge: No
article_type: original
author:
- first_name: Marlene
full_name: Bartos, Marlene
last_name: Bartos
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Axel
full_name: Meyer, Axel
last_name: Meyer
- first_name: Hannah
full_name: Monyer, Hannah
last_name: Monyer
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bartos M, Vida I, Frotscher M, et al. Fast synaptic inhibition promotes synchronized
gamma oscillations in hippocampal interneuron networks. PNAS. 2002;99(20):13222-13227.
doi:10.1073/pnas.192233099
apa: Bartos, M., Vida, I., Frotscher, M., Meyer, A., Monyer, H., Geiger, J., &
Jonas, P. M. (2002). Fast synaptic inhibition promotes synchronized gamma oscillations
in hippocampal interneuron networks. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.192233099
chicago: Bartos, Marlene, Imre Vida, Michael Frotscher, Axel Meyer, Hannah Monyer,
Jörg Geiger, and Peter M Jonas. “Fast Synaptic Inhibition Promotes Synchronized
Gamma Oscillations in Hippocampal Interneuron Networks.” PNAS. National
Academy of Sciences, 2002. https://doi.org/10.1073/pnas.192233099.
ieee: M. Bartos et al., “Fast synaptic inhibition promotes synchronized gamma
oscillations in hippocampal interneuron networks,” PNAS, vol. 99, no. 20.
National Academy of Sciences, pp. 13222–13227, 2002.
ista: Bartos M, Vida I, Frotscher M, Meyer A, Monyer H, Geiger J, Jonas PM. 2002.
Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks. PNAS. 99(20), 13222–13227.
mla: Bartos, Marlene, et al. “Fast Synaptic Inhibition Promotes Synchronized Gamma
Oscillations in Hippocampal Interneuron Networks.” PNAS, vol. 99, no. 20,
National Academy of Sciences, 2002, pp. 13222–27, doi:10.1073/pnas.192233099.
short: M. Bartos, I. Vida, M. Frotscher, A. Meyer, H. Monyer, J. Geiger, P.M. Jonas,
PNAS 99 (2002) 13222–13227.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-09-16T00:00:00Z
date_updated: 2023-07-10T13:35:18Z
day: '16'
doi: 10.1073/pnas.192233099
extern: '1'
external_id:
pmid:
- '12235359'
intvolume: ' 99'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130614/
month: '09'
oa: 1
oa_version: Published Version
page: 13222 - 13227
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2409'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 99
year: '2002'
...
---
_id: '3803'
abstract:
- lang: eng
text: Mossy fiber (MF) synapses are key stations for flow of information through
the hippocampal formation. A major component of the output of the MF system is
directed towards inhibitory interneurons. Recent studies have revealed that the
functional properties of MF-interneuron synapses differ substantially from those
of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum
lucidum represent a continuum of functional subtypes, in which the subunit composition
of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a
coordinated manner.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Bischofberger J, Jonas PM. TwoB or not twoB: differential transmission at
glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 2002;25(12):600-603. doi:10.1016/S0166-2236(02)02259-2'
apa: 'Bischofberger, J., & Jonas, P. M. (2002). TwoB or not twoB: differential
transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus.
Trends in Neurosciences. Elsevier. https://doi.org/10.1016/S0166-2236(02)02259-2'
chicago: 'Bischofberger, Josef, and Peter M Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences. Elsevier, 2002. https://doi.org/10.1016/S0166-2236(02)02259-2.'
ieee: 'J. Bischofberger and P. M. Jonas, “TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus,” Trends
in Neurosciences, vol. 25, no. 12. Elsevier, pp. 600–603, 2002.'
ista: 'Bischofberger J, Jonas PM. 2002. TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 25(12), 600–603.'
mla: 'Bischofberger, Josef, and Peter M. Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences, vol. 25, no. 12, Elsevier, 2002, pp. 600–03, doi:10.1016/S0166-2236(02)02259-2.'
short: J. Bischofberger, P.M. Jonas, Trends in Neurosciences 25 (2002) 600–603.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-07-10T13:22:24Z
day: '01'
doi: 10.1016/S0166-2236(02)02259-2
extern: '1'
external_id:
pmid:
- '12446120'
intvolume: ' 25'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 600 - 603
pmid: 1
publication: Trends in Neurosciences
publication_identifier:
issn:
- 0166-2236
publication_status: published
publisher: Elsevier
publist_id: '2408'
quality_controlled: '1'
status: public
title: 'TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron
synapses in the hippocampus'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 25
year: '2002'
...
---
_id: '3801'
abstract:
- lang: eng
text: 'To examine possible interactions between fast depression and modulation of
inhibitory synaptic transmission in the hippocampus, we recorded from pairs of
synaptically connected basket cells (BCs) and granule cells (GCs) in the dentate
gyrus of rat brain slices at 34 degrees C. Multiple-pulse depression (MPD) was
examined in trains of 5 or 10 inhibitory postsynaptic currents (IPSCs) evoked
at frequencies of 10-100 Hz under several conditions that inhibit transmitter
release: block of voltage-dependent Ca2+ channels by Cd2+ (10 microM), activation
of gamma-amino-butyric acid type B receptors (GABA(B)Rs) by baclofen (10 microM)
and activation of muscarinic acetylcholine receptors (mAchRs) by carbachol (2
microM). All manipulations led to a substantial inhibition of synaptic transmission,
reducing the amplitude of the first IPSC in the train (IPSC1) by 72%, 61% and
29%, respectively. However, MPD was largely preserved under these conditions (0.34
in control versus 0.31, 0.50 and 0.47 in the respective conditions at 50 Hz).
Similarly, a theta burst stimulation (TBS) protocol reduced IPSC1 by 54%, but
left MPD unchanged (0.40 in control and 0.39 during TBS). Analysis of both fractions
of transmission failures and coefficients of variation (CV) of IPSC peak amplitudes
suggested that MPD had a presynaptic expression site, independent of release probability.
In conclusion, different types of presynaptic modulation of inhibitory synaptic
transmission converge on a reduction of synaptic strength, while short-term dynamics
are largely unchanged.'
acknowledgement: We thank Drs M. Bartos, J. Bischofberger, M. Heckmann and
I. Vida for critically reading the manuscript, Dr K. Götz for providing information about pharmacological properties of
inhibitory hippocampal synapses, and A. Blomenkamp and K. Winterhalter for
technical assistance. This work was supported by Deutsche Forschungsgemeinschaft
grants to P.J. (Jo-248/2-2,SFB 505/C5) and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Stefan
full_name: Hefft, Stefan
last_name: Hefft
- first_name: Udo
full_name: Kraushaar, Udo
last_name: Kraushaar
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Hefft S, Kraushaar U, Geiger J, Jonas PM. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 2002;539(Pt 1):201-208. doi:10.1113/jphysiol.2001.013455
apa: Hefft, S., Kraushaar, U., Geiger, J., & Jonas, P. M. (2002). Presynaptic
short-term depression is maintained during regulation of transmitter release at
a GABAergic synapse in rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013455
chicago: Hefft, Stefan, Udo Kraushaar, Jörg Geiger, and Peter M Jonas. “Presynaptic
Short-Term Depression Is Maintained during Regulation of Transmitter Release at
a GABAergic Synapse in Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell,
2002. https://doi.org/10.1113/jphysiol.2001.013455.
ieee: S. Hefft, U. Kraushaar, J. Geiger, and P. M. Jonas, “Presynaptic short-term
depression is maintained during regulation of transmitter release at a GABAergic
synapse in rat hippocampus,” Journal of Physiology, vol. 539, no. Pt 1.
Wiley-Blackwell, pp. 201–8, 2002.
ista: Hefft S, Kraushaar U, Geiger J, Jonas PM. 2002. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 539(Pt 1), 201–8.
mla: Hefft, Stefan, et al. “Presynaptic Short-Term Depression Is Maintained during
Regulation of Transmitter Release at a GABAergic Synapse in Rat Hippocampus.”
Journal of Physiology, vol. 539, no. Pt 1, Wiley-Blackwell, 2002, pp. 201–08,
doi:10.1113/jphysiol.2001.013455.
short: S. Hefft, U. Kraushaar, J. Geiger, P.M. Jonas, Journal of Physiology 539
(2002) 201–8.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-07-11T10:01:12Z
day: '01'
doi: 10.1113/jphysiol.2001.013455
extern: '1'
external_id:
pmid:
- '11850513'
intvolume: ' 539'
issue: Pt 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290140/
month: '02'
oa: 1
oa_version: Published Version
page: 201 - 8
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2410'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Presynaptic short-term depression is maintained during regulation of transmitter
release at a GABAergic synapse in rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 539
year: '2002'
...
---
_id: '3799'
abstract:
- lang: eng
text: 'GABAergic interneurones are diverse in their morphological and functional
properties. Perisomatic inhibitory cells show fast spiking during sustained current
injection, whereas dendritic inhibitory cells fire action potentials with lower
frequency. We examined functional and molecular properties of K(+) channels in
interneurones with horizontal dendrites in stratum oriens-alveus (OA) of the hippocampal
CA1 region, which mainly comprise somatostatin-positive dendritic inhibitory cells.
Voltage-gated K(+) currents in nucleated patches isolated from OA interneurones
consisted of three major components: a fast delayed rectifier K(+) current component
that was highly sensitive to external 4-aminopyridine (4-AP) and tetraethylammonium
(TEA) (half-maximal inhibitory concentrations < 0.1 mM for both blockers),
a slow delayed rectifier K(+) current component that was sensitive to high concentrations
of TEA, but insensitive to 4-AP, and a rapidly inactivating A-type K(+) current
component that was blocked by high concentrations of 4-AP, but resistant to TEA.
The relative contributions of these components to the macroscopic K(+) current
were estimated as 57 +/- 5, 25 +/- 6, and 19 +/- 2 %, respectively. Dendrotoxin,
a selective blocker of Kv1 channels had only minimal effects on K(+) currents
in nucleated patches. Coapplication of the membrane-permeant cAMP analogue 8-(4-chlorophenylthio)-adenosine
3'':5''-cyclic monophosphate (cpt-cAMP) and the phosphodiesterase blocker isobutyl-methylxanthine
(IBMX) resulted in a selective inhibition of the fast delayed rectifier K(+) current
component. This inhibition was absent in the presence of the protein kinase A
(PKA) inhibitor H-89, implying the involvement of PKA-mediated phosphorylation.
Single-cell reverse transcription-polymerase chain reaction (RT-PCR) analysis
revealed a high abundance of Kv3.2 mRNA in OA interneurones, whereas the expression
level of Kv3.1 mRNA was markedly lower. Similarly, RT-PCR analysis showed a high
abundance of Kv4.3 mRNA, whereas Kv4.2 mRNA was undetectable. This suggests that
the fast delayed rectifier K(+) current and the A-type K(+) current component
are mediated predominantly by homomeric Kv3.2 and Kv4.3 channels. Selective modulation
of Kv3.2 channels in OA interneurones by cAMP is likely to be an important factor
regulating the activity of dendritic inhibitory cells in principal neurone-interneurone
microcircuits.'
acknowledgement: We thank Drs J. Bischofberger, M. Heckmann, and I. Vida for critically
reading the manuscript, and A. Blomenkamp and K. Winterhalter for technical assistance.
This work was supported by a scholarship from the Deutscher Akademischer Austansch
dienst to C.-C. L., a Deutsche Forschungsgemeinschaft grant to P. J. (SFB 505/C5),
and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Cheng
full_name: Lien, Cheng
last_name: Lien
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Jobst
full_name: Schultz, Jobst
last_name: Schultz
- first_name: Heimo
full_name: Ehmke, Heimo
last_name: Ehmke
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. Gating, modulation and subunit
composition of voltage-gated K(+) channels in dendritic inhibitory interneurones
of rat hippocampus. Journal of Physiology. 2002;538(Pt 2):405-419. doi:10.1113/jphysiol.2001.013066
apa: Lien, C., Martina, M., Schultz, J., Ehmke, H., & Jonas, P. M. (2002). Gating,
modulation and subunit composition of voltage-gated K(+) channels in dendritic
inhibitory interneurones of rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013066
chicago: Lien, Cheng, Marco Martina, Jobst Schultz, Heimo Ehmke, and Peter M Jonas.
“Gating, Modulation and Subunit Composition of Voltage-Gated K(+) Channels in
Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal of Physiology.
Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2001.013066.
ieee: C. Lien, M. Martina, J. Schultz, H. Ehmke, and P. M. Jonas, “Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus,” Journal of Physiology, vol. 538, no.
Pt 2. Wiley-Blackwell, pp. 405–419, 2002.
ista: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. 2002. Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus. Journal of Physiology. 538(Pt 2), 405–419.
mla: Lien, Cheng, et al. “Gating, Modulation and Subunit Composition of Voltage-Gated
K(+) Channels in Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal
of Physiology, vol. 538, no. Pt 2, Wiley-Blackwell, 2002, pp. 405–19, doi:10.1113/jphysiol.2001.013066.
short: C. Lien, M. Martina, J. Schultz, H. Ehmke, P.M. Jonas, Journal of Physiology
538 (2002) 405–419.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-11T12:32:26Z
day: '01'
doi: 10.1113/jphysiol.2001.013066
extern: '1'
external_id:
pmid:
- '11790809'
intvolume: ' 538'
issue: Pt 2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290075/
month: '01'
oa: 1
oa_version: Published Version
page: 405 - 419
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2411'
quality_controlled: '1'
status: public
title: Gating, modulation and subunit composition of voltage-gated K(+) channels in
dendritic inhibitory interneurones of rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 538
year: '2002'
...
---
_id: '3621'
abstract:
- lang: eng
text: In 1991, Barton and Turelli developed recursions to describe the evolution
of multilocus systems under arbitrary forms of selection. This article generalizes
their approach to allow for arbitrary modes of inheritance, including diploidy,
polyploidy, sex linkage, cytoplasmic inheritance, and genomic imprinting. The
framework is also extended to allow for other deterministic evolutionary forces,
including migration and mutation. Exact recursions that fully describe the state
of the population are presented; these are implemented in a computer algebra package
(available on the Web at http://helios.bto.ed.ac.uk/evolgen). Despite the generality
of our framework, it can describe evolutionary dynamics exactly by just two equations.
These recursions can be further simplified using a "quasi-linkage equilibrium"
(QLE) approximation. We illustrate the methods by finding the effect of natural
selection, sexual selection, mutation, and migration on the genetic composition
of a population.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Kirkpatrick, Mark
last_name: Kirkpatrick
- first_name: Toby
full_name: Johnson, Toby
last_name: Johnson
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Kirkpatrick M, Johnson T, Barton NH. General models of multilocus evolution.
Genetics. 2002;161(4):1727-1750. doi:10.1093/genetics/161.4.1727
apa: Kirkpatrick, M., Johnson, T., & Barton, N. H. (2002). General models of
multilocus evolution. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/161.4.1727
chicago: Kirkpatrick, Mark, Toby Johnson, and Nicholas H Barton. “General Models
of Multilocus Evolution.” Genetics. Genetics Society of America, 2002.
https://doi.org/10.1093/genetics/161.4.1727.
ieee: M. Kirkpatrick, T. Johnson, and N. H. Barton, “General models of multilocus
evolution,” Genetics, vol. 161, no. 4. Genetics Society of America, pp.
1727–1750, 2002.
ista: Kirkpatrick M, Johnson T, Barton NH. 2002. General models of multilocus evolution.
Genetics. 161(4), 1727–1750.
mla: Kirkpatrick, Mark, et al. “General Models of Multilocus Evolution.” Genetics,
vol. 161, no. 4, Genetics Society of America, 2002, pp. 1727–50, doi:10.1093/genetics/161.4.1727.
short: M. Kirkpatrick, T. Johnson, N.H. Barton, Genetics 161 (2002) 1727–1750.
date_created: 2018-12-11T12:04:17Z
date_published: 2002-08-01T00:00:00Z
date_updated: 2023-07-11T13:20:26Z
day: '01'
doi: 10.1093/genetics/161.4.1727
extern: '1'
external_id:
pmid:
- '12196414'
intvolume: ' 161'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462196/
month: '08'
oa: 1
oa_version: Published Version
page: 1727 - 1750
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '2762'
quality_controlled: '1'
scopus_import: '1'
status: public
title: General models of multilocus evolution
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 161
year: '2002'
...
---
_id: '3757'
abstract:
- lang: eng
text: A central problem in biology is determining how genes interact as parts of
functional networks. Creation and analysis of synthetic networks, composed of
well-characterized genetic elements, provide a framework for theoretical modeling.
Here, with the use of a combinatorial method, a library of networks with varying
connectivity was generated in Escherichia coli. These networks were composed of
genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well
as the corresponding promoters. They displayed phenotypic behaviors resembling
binary logical circuits, with two chemical “inputs” and a fluorescent protein
“output.” Within this simple system, diverse computational functions arose through
changes in network connectivity. Combinatorial synthesis provides an alternative
approach for studying biological networks, as well as an efficient method for
producing diverse phenotypes in vivo.
article_processing_charge: No
article_type: original
author:
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Michael
full_name: Elowitz, Michael
last_name: Elowitz
- first_name: Weihong
full_name: Hsing, Weihong
last_name: Hsing
- first_name: Stanislas
full_name: Leibler, Stanislas
last_name: Leibler
citation:
ama: Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic
networks. Science. 2002;296(5572):1466-1470. doi:10.1126/science.1067407
apa: Guet, C. C., Elowitz, M., Hsing, W., & Leibler, S. (2002). Combinatorial
synthesis of genetic networks. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1067407
chicago: Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial
Synthesis of Genetic Networks.” Science. American Association for the Advancement
of Science, 2002. https://doi.org/10.1126/science.1067407.
ieee: C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis
of genetic networks,” Science, vol. 296, no. 5572. American Association
for the Advancement of Science, pp. 1466–1470, 2002.
ista: Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic
networks. Science. 296(5572), 1466–1470.
mla: Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” Science,
vol. 296, no. 5572, American Association for the Advancement of Science, 2002,
pp. 1466–70, doi:10.1126/science.1067407.
short: C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470.
date_created: 2018-12-11T12:05:00Z
date_published: 2002-05-24T00:00:00Z
date_updated: 2023-07-11T12:48:53Z
day: '24'
doi: 10.1126/science.1067407
extern: '1'
external_id:
pmid:
- '12029133'
intvolume: ' 296'
issue: '5572'
language:
- iso: eng
month: '05'
oa_version: None
page: 1466 - 1470
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2471'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Combinatorial synthesis of genetic networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 296
year: '2002'
...
---
_id: '3497'
abstract:
- lang: eng
text: The use of advanced patch-clamp recording techniques in brain slices, such
as simultaneous recording from multiple neurons and recording from dendrites or
presynaptic terminals, demands slices of the highest quality. In this context
the mechanics of the tissue slicer are an important factor. Ideally, a tissue
slicer should generate large-amplitude and high-frequency movements of the cutting
blade in a horizontal axis, with minimal vibrations in the vertical axis. We developed
a vibroslicer that fulfils these in part conflicting requirements. The oscillator
is a permanent-magnet-coil-leaf-spring system. Using an auto-resonant mechano-electrical
feedback circuit, large horizontal oscillations (up to 3 mm peak-to-peak) with
high frequency (,90 Hz) are generated. To minimize vertical vibrations, an adjustment
mechanism was employed that allowed alignment of the cutting edge of the blade
with the major axis of the oscillation. A vibroprobe device was used to monitor
vertical vibrations during adjustment. The system is based on the shading of the
light path between a light-emitting diode (LED) and a photodiode. Vibroprobe monitoring
revealed that the vibroslicer, after appropriate adjustment, generated vertical
vibrations of <1 µm, significantly less than many commercial tissue slicers.
Light- and electron-microscopic analysis of surface layers of slices cut with
the vibroslicer showed that cellular elements, dendritic processes and presynaptic
terminals are well preserved under these conditions, as required for patch-clamp
recording from these structures.
acknowledgement: "We thank Dr. M. Frotscher for reading the manuscript, and H. Kressner,
R. Laufersweiler, and A. Bühler for help with the construction of several prototypes
of vibroslicer and vibroprobe. We also thank A. Blomenkamp, K. Winterhalter, B.
Joch, and A. Schneider for technical assistance. This work was supported by grants
of the Deutsche Forschungsgemeinschaft\r\n(SFB 505/C5, C6) and the Human Frontiers
Science Program Organization (RG0017/1998-B)."
article_processing_charge: No
article_type: original
author:
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Joseph
full_name: Bischofberger, Joseph
last_name: Bischofberger
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Ulrich
full_name: Fröbe, Ulrich
last_name: Fröbe
- first_name: S
full_name: Pfitzinger, S
last_name: Pfitzinger
- first_name: H.
full_name: Weber, H.
last_name: Weber
- first_name: Klaus
full_name: Haverkampf, Klaus
last_name: Haverkampf
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Geiger J, Bischofberger J, Vida I, et al. Patch-clamp recording in brain slices
with improved slicer technology. Pflugers Archiv : European Journal of Physiology.
2002;443(3):491-501. doi:10.1007/s00424-001-0735-3'
apa: 'Geiger, J., Bischofberger, J., Vida, I., Fröbe, U., Pfitzinger, S., Weber,
H., … Jonas, P. M. (2002). Patch-clamp recording in brain slices with improved
slicer technology. Pflugers Archiv : European Journal of Physiology. Springer.
https://doi.org/10.1007/s00424-001-0735-3'
chicago: 'Geiger, Jörg, Joseph Bischofberger, Imre Vida, Ulrich Fröbe, S Pfitzinger,
H. Weber, Klaus Haverkampf, and Peter M Jonas. “Patch-Clamp Recording in Brain
Slices with Improved Slicer Technology.” Pflugers Archiv : European Journal
of Physiology. Springer, 2002. https://doi.org/10.1007/s00424-001-0735-3.'
ieee: 'J. Geiger et al., “Patch-clamp recording in brain slices with improved
slicer technology,” Pflugers Archiv : European Journal of Physiology, vol.
443, no. 3. Springer, pp. 491–501, 2002.'
ista: 'Geiger J, Bischofberger J, Vida I, Fröbe U, Pfitzinger S, Weber H, Haverkampf
K, Jonas PM. 2002. Patch-clamp recording in brain slices with improved slicer
technology. Pflugers Archiv : European Journal of Physiology. 443(3), 491–501.'
mla: 'Geiger, Jörg, et al. “Patch-Clamp Recording in Brain Slices with Improved
Slicer Technology.” Pflugers Archiv : European Journal of Physiology, vol.
443, no. 3, Springer, 2002, pp. 491–501, doi:10.1007/s00424-001-0735-3.'
short: 'J. Geiger, J. Bischofberger, I. Vida, U. Fröbe, S. Pfitzinger, H. Weber,
K. Haverkampf, P.M. Jonas, Pflugers Archiv : European Journal of Physiology 443
(2002) 491–501.'
date_created: 2018-12-11T12:03:38Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-17T07:36:37Z
day: '01'
doi: 10.1007/s00424-001-0735-3
extern: '1'
external_id:
pmid:
- '11810221'
intvolume: ' 443'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 491 - 501
pmid: 1
publication: 'Pflugers Archiv : European Journal of Physiology'
publication_identifier:
issn:
- 0031-6768
publication_status: published
publisher: Springer
publist_id: '2890'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Patch-clamp recording in brain slices with improved slicer technology
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 443
year: '2002'
...
---
_id: '3533'
abstract:
- lang: eng
text: 'Information in neuronal networks is thought to be represented by the rate
of discharge and the temporal relationship between the discharging neurons. The
discharge frequency of neurons is affected by their afferents and intrinsic properties,
and shows great individual variability. The temporal coordination of neurons is
greatly facilitated by network oscillations. In the hippocampus, population synchrony
fluctuates during theta and gamma oscillations (10-100 ms scale) and can increase
almost 10-fold during sharp wave bursts. Despite these large changes in excitability
in the sub-second scale, longer-term (minute-scale) firing rates of individual
neurons are relatively constant in an unchanging environment. As a result, mean
hippocampal output remains stable over time. To understand the mechanisms responsible
for this homeostasis, we address the following issues: (i) Can firing rates of
single cells be modified? (ii) Once modified, what mechanism(s) can maintain the
changes? We show that firing rates of hippocampal pyramidal cells can be altered
in a novel environment and by Hebbian pairing of physiological input patterns
with postsynaptic burst discharge. We also illustrate a competition between single
spikes and the occurrence of spike bursts. Since spike-inducing (suprathreshold)
inputs decrease the ability of strong (''teaching'') inputs to induce a burst
discharge, we propose that the single spike versus burst competition presents
a homeostatic regulatory mechanism to maintain synaptic strength and, consequently,
firing rate in pyramidal cells.'
article_processing_charge: No
article_type: original
author:
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: George
full_name: Dragoi, George
last_name: Dragoi
- first_name: Kenneth
full_name: Harris, Kenneth
last_name: Harris
- first_name: D.
full_name: Henze, D.
last_name: Henze
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
citation:
ama: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic
maintenance of neuronal excitability by burst discharges in vivo. Cerebral
Cortex. 2002;12(9):893-899. doi:10.1093/cercor/12.9.893
apa: Buzsáki, G., Csicsvari, J. L., Dragoi, G., Harris, K., Henze, D., & Hirase,
H. (2002). Homeostatic maintenance of neuronal excitability by burst discharges
in vivo. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/12.9.893
chicago: Buzsáki, György, Jozsef L Csicsvari, George Dragoi, Kenneth Harris, D.
Henze, and Hajima Hirase. “Homeostatic Maintenance of Neuronal Excitability by
Burst Discharges in Vivo.” Cerebral Cortex. Oxford University Press, 2002.
https://doi.org/10.1093/cercor/12.9.893.
ieee: G. Buzsáki, J. L. Csicsvari, G. Dragoi, K. Harris, D. Henze, and H. Hirase,
“Homeostatic maintenance of neuronal excitability by burst discharges in vivo,”
Cerebral Cortex, vol. 12, no. 9. Oxford University Press, pp. 893–899,
2002.
ista: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. 2002. Homeostatic
maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex.
12(9), 893–899.
mla: Buzsáki, György, et al. “Homeostatic Maintenance of Neuronal Excitability by
Burst Discharges in Vivo.” Cerebral Cortex, vol. 12, no. 9, Oxford University
Press, 2002, pp. 893–99, doi:10.1093/cercor/12.9.893.
short: G. Buzsáki, J.L. Csicsvari, G. Dragoi, K. Harris, D. Henze, H. Hirase, Cerebral
Cortex 12 (2002) 893–899.
date_created: 2018-12-11T12:03:50Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-07-17T07:27:12Z
day: '01'
doi: 10.1093/cercor/12.9.893
extern: '1'
external_id:
pmid:
- '12183388'
intvolume: ' 12'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 893 - 899
pmid: 1
publication: Cerebral Cortex
publication_identifier:
issn:
- 1047-3211
publication_status: published
publisher: Oxford University Press
publist_id: '2851'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Homeostatic maintenance of neuronal excitability by burst discharges in vivo
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3424'
abstract:
- lang: eng
text: "We give a brief overview of the current understanding of the explosion mechanism
of core collapse supernovae. Our main focus is the impact of rotation on the explosion.
Recent observations of the polarization of the light emitted by supernova explosions
indicate that there are large deviations from spherical symmetry in the very heart
of the explosion the origin of which is unknown. We use the new approach of a
three dimensional test particle based simulation to simulate the infall phase
of a supernova event. The underlying microphysics is simplified to make this computationally
possible. A systematic study of the influence of rotation mainly during the infall
phase of the collapse of a typical iron core is performed. Indications for significant
deviations from spherical symmetry are found in our very rapidly rotating models.
© 2002 American Institute of Physics\r\n"
alternative_title:
- Exotic Clustering, American Institute of Physics Conference Proceedings
article_processing_charge: No
author:
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Wolfgang
full_name: Bauer, Wolfgang
last_name: Bauer
citation:
ama: 'Bollenbach MT, Bauer W. 3d supernovae collapse calculations. In: Vol 644.
American Institute of Physics; 2002:219-232. doi:10.1063/1.1523196 '
apa: 'Bollenbach, M. T., & Bauer, W. (2002). 3d supernovae collapse calculations
(Vol. 644, pp. 219–232). Presented at the CRIS: Catania Relativistic Ion Studies
, Catania, Italy: American Institute of Physics. https://doi.org/10.1063/1.1523196 '
chicago: Bollenbach, Mark Tobias, and Wolfgang Bauer. “3d Supernovae Collapse Calculations,”
644:219–32. American Institute of Physics, 2002. https://doi.org/10.1063/1.1523196 .
ieee: 'M. T. Bollenbach and W. Bauer, “3d supernovae collapse calculations,” presented
at the CRIS: Catania Relativistic Ion Studies , Catania, Italy, 2002, vol. 644,
pp. 219–232.'
ista: 'Bollenbach MT, Bauer W. 2002. 3d supernovae collapse calculations. CRIS:
Catania Relativistic Ion Studies , Exotic Clustering, American Institute of Physics
Conference Proceedings, vol. 644, 219–232.'
mla: Bollenbach, Mark Tobias, and Wolfgang Bauer. 3d Supernovae Collapse Calculations.
Vol. 644, American Institute of Physics, 2002, pp. 219–32, doi:10.1063/1.1523196 .
short: M.T. Bollenbach, W. Bauer, in:, American Institute of Physics, 2002, pp.
219–232.
conference:
end_date: 2002-06-14
location: Catania, Italy
name: 'CRIS: Catania Relativistic Ion Studies '
start_date: 2002-06-10
date_created: 2018-12-11T12:03:15Z
date_published: 2002-11-26T00:00:00Z
date_updated: 2023-07-17T11:05:27Z
day: '26'
doi: '10.1063/1.1523196 '
extern: '1'
intvolume: ' 644'
language:
- iso: eng
month: '11'
oa_version: None
page: 219 - 232
publication_identifier:
isbn:
- '9781510832008'
publication_status: published
publisher: American Institute of Physics
publist_id: '2977'
quality_controlled: '1'
status: public
title: 3d supernovae collapse calculations
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 644
year: '2002'
...
---
_id: '2988'
abstract:
- lang: eng
text: Coordination of cell and tissue polarity commonly involves directional signaling
[1]. In the Arabidopsis root epidermis, cell polarity is revealed by basal, root
tip-oriented, hair outgrowth from hair-forming cells (trichoblasts) [2]. The plant
hormone auxin displays polar movements [1, 3] and accumulates at maximum concentration
in the root tip [4, 5]. The application of polar auxin transport inhibitors [3]
evokes changes in trichoblast polarity only at high concentrations and after long-term
application [2, 4]. Thus, it remains open whether components of the auxin transport
machinery mediate establishment of trichoblast polarity. Here we report that the
presumptive auxin influx carrier AUX1 [6, 7] contributes to apical-basal hair
cell polarity. AUX1 function is required for polarity changes induced by exogenous
application of the auxin 2,4-D, a preferential influx carrier substrate. Similar
to aux1 mutants, the vesicle trafficking inhibitor brefeldin A (BFA) interferes
with polar hair initiation, and AUX1 function is required for BFA-mediated polarity
changes. Consistently, BFA inhibits membrane trafficking of AUX1, trichoblast
hyperpolarization induced by 2,4-D, and alters the distal auxin maximum. Our results
identify AUX1 as one component of a novel BFA-sensitive auxin transport pathway
polarizing cells toward a hormone maximum.
article_processing_charge: No
article_type: original
author:
- first_name: Markus
full_name: Grebe, Markus
last_name: Grebe
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Göran
full_name: Sandberg, Göran
last_name: Sandberg
- first_name: Maarten
full_name: Terlou, Maarten
last_name: Terlou
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
citation:
ama: Grebe M, Friml J, Swarup R, et al. Cell polarity signaling in Arabidopsis involves
a BFA sensitive auxin influx pathway. Current Biology. 2002;12(4):329-334.
doi:10.1016/S0960-9822(02)00654-1
apa: Grebe, M., Friml, J., Swarup, R., Ljung, K., Sandberg, G., Terlou, M., … Scheres,
B. (2002). Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin
influx pathway. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00654-1
chicago: Grebe, Markus, Jiří Friml, Ranjan Swarup, Karin Ljung, Göran Sandberg,
Maarten Terlou, Klaus Palme, Malcolm Bennett, and Ben Scheres. “Cell Polarity
Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” Current
Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00654-1.
ieee: M. Grebe et al., “Cell polarity signaling in Arabidopsis involves a
BFA sensitive auxin influx pathway,” Current Biology, vol. 12, no. 4. Cell
Press, pp. 329–334, 2002.
ista: Grebe M, Friml J, Swarup R, Ljung K, Sandberg G, Terlou M, Palme K, Bennett
M, Scheres B. 2002. Cell polarity signaling in Arabidopsis involves a BFA sensitive
auxin influx pathway. Current Biology. 12(4), 329–334.
mla: Grebe, Markus, et al. “Cell Polarity Signaling in Arabidopsis Involves a BFA
Sensitive Auxin Influx Pathway.” Current Biology, vol. 12, no. 4, Cell
Press, 2002, pp. 329–34, doi:10.1016/S0960-9822(02)00654-1.
short: M. Grebe, J. Friml, R. Swarup, K. Ljung, G. Sandberg, M. Terlou, K. Palme,
M. Bennett, B. Scheres, Current Biology 12 (2002) 329–334.
date_created: 2018-12-11T12:00:43Z
date_published: 2002-02-19T00:00:00Z
date_updated: 2023-07-17T12:15:28Z
day: '19'
doi: 10.1016/S0960-9822(02)00654-1
extern: '1'
external_id:
pmid:
- '11864575'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 329 - 334
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '3714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx
pathway
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3421'
abstract:
- lang: eng
text: Single molecule experiments provide insight into the individuality of biological
macromolecules, their unique function, reaction pathways, trajectories and molecular
interactions. The exceptional signal-to-noise ratio of the atomic force microscope
allows individual proteins to be imaged under physiologically relevant conditions
at a lateral resolution of 0.5–1 nm and a vertical resolution of 0.1–0.2 nm. Recently,
it has become possible to observe single molecule events using this technique.
This capability is reviewed on various water-soluble and membrane proteins. Examples
of the observation of function, variability, and assembly of single proteins are
discussed. Statistical analysis is important to extend conclusions derived from
single molecule experiments to protein species. Such approaches allow the classification
of protein conformations and movements. Recent developments of probe microscopy
techniques allow simultaneous measurement of multiple signals on individual macromolecules,
and greatly extend the range of experiments possible for probing biological systems
at the molecular level. Biologists exploring molecular mechanisms will benefit
from a burgeoning of scanning probe microscopes and of their future combination
with molecular biological experiments.
article_processing_charge: No
article_type: review
author:
- first_name: Daniel
full_name: Mueller, Daniel
last_name: Mueller
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Tiina
full_name: Lehto, Tiina
last_name: Lehto
- first_name: Lars
full_name: Kuerschner, Lars
last_name: Kuerschner
- first_name: Kurt
full_name: Anderson, Kurt
last_name: Anderson
citation:
ama: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. Observing structure,
function and assembly of single proteins by AFM. Progress in Biophysics and
Molecular Biology. 2002;79(1-3):1-43. doi:10.1016/S0079-6107(02)00009-3
apa: Mueller, D., Janovjak, H. L., Lehto, T., Kuerschner, L., & Anderson, K.
(2002). Observing structure, function and assembly of single proteins by AFM.
Progress in Biophysics and Molecular Biology. Elsevier. https://doi.org/10.1016/S0079-6107(02)00009-3
chicago: Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt
Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.”
Progress in Biophysics and Molecular Biology. Elsevier, 2002. https://doi.org/10.1016/S0079-6107(02)00009-3.
ieee: D. Mueller, H. L. Janovjak, T. Lehto, L. Kuerschner, and K. Anderson, “Observing
structure, function and assembly of single proteins by AFM,” Progress in Biophysics
and Molecular Biology, vol. 79, no. 1–3. Elsevier, pp. 1–43, 2002.
ista: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. 2002. Observing
structure, function and assembly of single proteins by AFM. Progress in Biophysics
and Molecular Biology. 79(1–3), 1–43.
mla: Mueller, Daniel, et al. “Observing Structure, Function and Assembly of Single
Proteins by AFM.” Progress in Biophysics and Molecular Biology, vol. 79,
no. 1–3, Elsevier, 2002, pp. 1–43, doi:10.1016/S0079-6107(02)00009-3.
short: D. Mueller, H.L. Janovjak, T. Lehto, L. Kuerschner, K. Anderson, Progress
in Biophysics and Molecular Biology 79 (2002) 1–43.
date_created: 2018-12-11T12:03:14Z
date_published: 2002-05-01T00:00:00Z
date_updated: 2023-07-17T11:36:32Z
day: '01'
doi: 10.1016/S0079-6107(02)00009-3
extern: '1'
external_id:
pmid:
- '12225775'
intvolume: ' 79'
issue: 1-3
language:
- iso: eng
month: '05'
oa_version: None
page: 1 - 43
pmid: 1
publication: Progress in Biophysics and Molecular Biology
publication_identifier:
issn:
- 0079-6107
publication_status: published
publisher: Elsevier
publist_id: '2980'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Observing structure, function and assembly of single proteins by AFM
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 79
year: '2002'
...
---
_id: '2989'
abstract:
- lang: eng
text: In contrast to animals, little is known about pattern formation in plants.
Physiological and genetic data suggest the involvement of the phytohormone auxin
in this process. Here, we characterize a novel member of the PIN family of putative
auxin efflux carriers, Arabidopsis PIN4, that is localized in developing and mature
root meristems. Atpin4 mutants are defective in establishment and maintenance
of endogenous auxin gradients, fail to canalize externally applied auxin, and
display various patterning defects in both embryonic and seedling roots. We propose
a role for AtPIN4 in generating a sink for auxin below the quiescent center of
the root meristem that is essential for auxin distribution and patterning.
acknowledgement: We thank Petra Tänzler, Michaela Lehnen, and Thomas Steinmann for
technical help. We acknowledge the Arabidopsis Biological Resource Center (Columbus,
OH) and Thomas Altman for providing material. We also gratefully acknowledge the
ADIS service group for DNA sequencing and ZIGIA (Center for Functional Genomics
in Arabidopsis) for the En lines. We are grateful to our colleagues, particularly
Leo Gälweiler, Niko Geldner, Matthias Godde, and Kathrin Schrick for critical reading
of the manuscript. This work was supported by a fellowship of the Deutscher Akademischer
Austauschdienset (J.F.), the Deutsche Forschungsgemeinschaft (Schwerpunktprogramm
Phytohormone), the European Communities Biotechnology Programs, the Fonds der Chemischen
Industrie, and the INCO-Copernicus Program.
article_processing_charge: No
article_type: original
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Ikram
full_name: Blilou, Ikram
last_name: Blilou
- first_name: Justyna
full_name: Wiśniewska, Justyna
last_name: Wiśniewska
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Scott
full_name: Woody, Scott
last_name: Woody
- first_name: Göran
full_name: Sandberg, Göran
last_name: Sandberg
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
citation:
ama: Friml J, Benková E, Blilou I, et al. AtPIN4 mediates sink-driven auxin gradients
and root patterning in Arabidopsis. Cell. 2002;108(5):661-673. doi:10.1016/S0092-8674(02)00656-6
apa: Friml, J., Benková, E., Blilou, I., Wiśniewska, J., Hamann, T., Ljung, K.,
… Palme, K. (2002). AtPIN4 mediates sink-driven auxin gradients and root patterning
in Arabidopsis. Cell. Cell Press. https://doi.org/10.1016/S0092-8674(02)00656-6
chicago: Friml, Jiří, Eva Benková, Ikram Blilou, Justyna Wiśniewska, Thorsten Hamann,
Karin Ljung, Scott Woody, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients
and Root Patterning in Arabidopsis.” Cell. Cell Press, 2002. https://doi.org/10.1016/S0092-8674(02)00656-6.
ieee: J. Friml et al., “AtPIN4 mediates sink-driven auxin gradients and root
patterning in Arabidopsis,” Cell, vol. 108, no. 5. Cell Press, pp. 661–673,
2002.
ista: Friml J, Benková E, Blilou I, Wiśniewska J, Hamann T, Ljung K, Woody S, Sandberg
G, Scheres B, Jürgens G, Palme K. 2002. AtPIN4 mediates sink-driven auxin gradients
and root patterning in Arabidopsis. Cell. 108(5), 661–673.
mla: Friml, Jiří, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning
in Arabidopsis.” Cell, vol. 108, no. 5, Cell Press, 2002, pp. 661–73, doi:10.1016/S0092-8674(02)00656-6.
short: J. Friml, E. Benková, I. Blilou, J. Wiśniewska, T. Hamann, K. Ljung, S. Woody,
G. Sandberg, B. Scheres, G. Jürgens, K. Palme, Cell 108 (2002) 661–673.
date_created: 2018-12-11T12:00:43Z
date_published: 2002-03-08T00:00:00Z
date_updated: 2023-07-17T11:57:40Z
day: '08'
doi: 10.1016/S0092-8674(02)00656-6
extern: '1'
external_id:
pmid:
- '11893337'
intvolume: ' 108'
issue: '5'
language:
- iso: eng
month: '03'
oa_version: None
page: 661 - 673
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Cell Press
publist_id: '3713'
quality_controlled: '1'
scopus_import: '1'
status: public
title: AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 108
year: '2002'
...
---
_id: '3422'
abstract:
- lang: eng
text: Quantitative real-time PCR represents a highly sensitive and powerful technique
for the quantitation of nucleic acids. It has a tremendous potential for the high-throughput
analysis of gene expression in research and routine diagnostics. However, the
major hurdle is not the practical performance of the experiments themselves but
rather the efficient evaluation and the mathematical and statistical analysis
of the enormous amount of data gained by this technology, as these functions are
not included in the software provided by the manufacturers of the detection systems.
In this work, we focus on the mathematical evaluation and analysis of the data
generated by quantitative real-time PCR, the calculation of the final results,
the propagation of experimental variation of the measured values to the final
results, and the statistical analysis. We developed a Microsoft Excel-based software
application coded in Visual Basic for Applications, called Q-Gene, which addresses
these points. Q-Gene manages and expedites the planning, performance, and evaluation
of quantitative real-time PCR experiments, as well as the mathematical and statistical
analysis, storage, and graphical presentation of the data. The Q-Gene software
application is a tool to cope with complex quantitative real-time PCR experiments
at a high-throughput scale and considerably expedites and rationalizes the experimental
setup, data analysis, and data management while ensuring highest reproducibility.
article_processing_charge: No
article_type: original
author:
- first_name: Patrick
full_name: Müller, Patrick
last_name: Müller
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Andre
full_name: Miserez, Andre
last_name: Miserez
- first_name: Zuzana
full_name: Dobbie, Zuzana
last_name: Dobbie
citation:
ama: Müller P, Janovjak HL, Miserez A, Dobbie Z. Processing of gene expression data
generated by quantitative real-time RT-PCR. Biotechniques. 2002;32(6):1372-1379.
apa: Müller, P., Janovjak, H. L., Miserez, A., & Dobbie, Z. (2002). Processing
of gene expression data generated by quantitative real-time RT-PCR. Biotechniques.
Informa Healthcare.
chicago: Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing
of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques.
Informa Healthcare, 2002.
ieee: P. Müller, H. L. Janovjak, A. Miserez, and Z. Dobbie, “Processing of gene
expression data generated by quantitative real-time RT-PCR,” Biotechniques,
vol. 32, no. 6. Informa Healthcare, pp. 1372–1379, 2002.
ista: Müller P, Janovjak HL, Miserez A, Dobbie Z. 2002. Processing of gene expression
data generated by quantitative real-time RT-PCR. Biotechniques. 32(6), 1372–1379.
mla: Müller, Patrick, et al. “Processing of Gene Expression Data Generated by Quantitative
Real-Time RT-PCR.” Biotechniques, vol. 32, no. 6, Informa Healthcare, 2002,
pp. 1372–79.
short: P. Müller, H.L. Janovjak, A. Miserez, Z. Dobbie, Biotechniques 32 (2002)
1372–1379.
date_created: 2018-12-11T12:03:15Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-17T11:29:06Z
day: '01'
extern: '1'
external_id:
pmid:
- '12074169'
intvolume: ' 32'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 1372 - 1379
pmid: 1
publication: Biotechniques
publication_identifier:
issn:
- 0736-6205
publication_status: published
publisher: Informa Healthcare
publist_id: '2979'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Processing of gene expression data generated by quantitative real-time RT-PCR
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 32
year: '2002'
...
---
_id: '3140'
abstract:
- lang: eng
text: The maturation of synaptic structures depends on inductive interactions between
axons and their prospective targets. One example of such an interaction is the
influence of proprioceptive sensory axons on the differentiation of muscle spindles.
We have monitored the expression of three transcription factors, Egr3, Pea3, and
Erm, that delineate early muscle spindle development in an assay of muscle spindle-inducing
signals. We provide genetic evidence that Neuregulin1 (Nrg1) is required for proprioceptive
afferent-evoked induction of muscle spindle differentiation in the mouse. Ig-Nrg1
isoforms are preferentially expressed by proprioceptive sensory neurons and are
sufficient to induce muscle spindle differentiation in vivo, whereas CRD-Nrg1
isoforms are broadly expressed in sensory and motor neurons but are not required
for muscle spindle induction.
acknowledgement: We thank L. Role for generously providing the CRD-Nrg1 mutant allele
for these studies, L. Parada and D. Anderson for sharing the TrkC and Ngn1 mouse
strains, W. Tourtellotte for providing Egr3 mutant mice, E. Avetisova for expert
technical assistance, X. Yang for experimental help in the initial phase of these
studies, A. Garratt for advice with ErbB antibodies, and L. Role and G. Fischbach
for helpful discussions. The CRD-Nrg1 mutant allele was generated in the lab of
Dr. Lorna Role, with the support of NIH grant NS29071. S.A. and S.H. were supported
by a grant from the Swiss National Science Foundation and the Kanton of Basel-Stadt.
S.J.B. was supported by grants from the NINDS. N.A.S. was supported by a Howard
Hughes Medical Institute Postdoctoral Fellowship for Physicians and a Career Development
Award from the NINDS. T.M.J. was supported by grants from NINDS and is an Investigator
of the Howard Hughes Medical Institute.
article_processing_charge: No
article_type: original
author:
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Neil
full_name: Shneider, Neil
last_name: Shneider
- first_name: Carmen
full_name: Birchmeier, Carmen
last_name: Birchmeier
- first_name: Steven
full_name: Burden, Steven
last_name: Burden
- first_name: Thomas
full_name: Jessell, Thomas
last_name: Jessell
- first_name: Silvia
full_name: Arber, Silvia
last_name: Arber
citation:
ama: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. A role
for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002;36(6):1035-1049.
doi:10.1016/S0896-6273(02)01101-7
apa: Hippenmeyer, S., Shneider, N., Birchmeier, C., Burden, S., Jessell, T., &
Arber, S. (2002). A role for Neuregulin1 signaling in muscle spindle differentiation.
Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)01101-7
chicago: Hippenmeyer, Simon, Neil Shneider, Carmen Birchmeier, Steven Burden, Thomas
Jessell, and Silvia Arber. “A Role for Neuregulin1 Signaling in Muscle Spindle
Differentiation.” Neuron. Elsevier, 2002. https://doi.org/10.1016/S0896-6273(02)01101-7.
ieee: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, and S.
Arber, “A role for Neuregulin1 signaling in muscle spindle differentiation,” Neuron,
vol. 36, no. 6. Elsevier, pp. 1035–1049, 2002.
ista: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. 2002.
A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 36(6),
1035–1049.
mla: Hippenmeyer, Simon, et al. “A Role for Neuregulin1 Signaling in Muscle Spindle
Differentiation.” Neuron, vol. 36, no. 6, Elsevier, 2002, pp. 1035–49,
doi:10.1016/S0896-6273(02)01101-7.
short: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, S. Arber,
Neuron 36 (2002) 1035–1049.
date_created: 2018-12-11T12:01:37Z
date_published: 2002-12-19T00:00:00Z
date_updated: 2023-07-17T11:46:43Z
day: '19'
doi: 10.1016/S0896-6273(02)01101-7
extern: '1'
external_id:
pmid:
- '12495620'
intvolume: ' 36'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 1035 - 1049
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '3558'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A role for Neuregulin1 signaling in muscle spindle differentiation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 36
year: '2002'
...
---
_id: '3423'
article_processing_charge: No
author:
- first_name: Wolfgang
full_name: Bauer, Wolfgang
last_name: Bauer
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Marko
full_name: Kleine Berkenbusch, Marko
last_name: Kleine Berkenbusch
- first_name: Holger
full_name: Harreis, Holger
last_name: Harreis
citation:
ama: 'Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. The percolation interpretation
of the nuclear fragmentation phase transition. In: Proceedings of the 18th
Winter Workshop on Nuclear Dynamics. EP Systema; 2002:111-118.'
apa: 'Bauer, W., Bollenbach, M. T., Kleine Berkenbusch, M., & Harreis, H. (2002).
The percolation interpretation of the nuclear fragmentation phase transition.
In Proceedings of the 18th Winter Workshop on Nuclear Dynamics (pp. 111–118).
Nassau, Bahamas: EP Systema.'
chicago: Bauer, Wolfgang, Mark Tobias Bollenbach, Marko Kleine Berkenbusch, and
Holger Harreis. “The Percolation Interpretation of the Nuclear Fragmentation Phase
Transition.” In Proceedings of the 18th Winter Workshop on Nuclear Dynamics,
111–18. EP Systema, 2002.
ieee: W. Bauer, M. T. Bollenbach, M. Kleine Berkenbusch, and H. Harreis, “The percolation
interpretation of the nuclear fragmentation phase transition,” in Proceedings
of the 18th Winter Workshop on Nuclear Dynamics, Nassau, Bahamas, 2002, pp.
111–118.
ista: Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. 2002. The percolation
interpretation of the nuclear fragmentation phase transition. Proceedings of the
18th Winter Workshop on Nuclear Dynamics. Winter Workshop on Nuclear Dynamics,
111–118.
mla: Bauer, Wolfgang, et al. “The Percolation Interpretation of the Nuclear Fragmentation
Phase Transition.” Proceedings of the 18th Winter Workshop on Nuclear Dynamics,
EP Systema, 2002, pp. 111–18.
short: W. Bauer, M.T. Bollenbach, M. Kleine Berkenbusch, H. Harreis, in:, Proceedings
of the 18th Winter Workshop on Nuclear Dynamics, EP Systema, 2002, pp. 111–118.
conference:
end_date: 2002-01-22
location: Nassau, Bahamas
name: Winter Workshop on Nuclear Dynamics
start_date: 2002-01-20
date_created: 2018-12-11T12:03:15Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-17T11:15:14Z
day: '01'
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 111 - 118
publication: Proceedings of the 18th Winter Workshop on Nuclear Dynamics
publication_status: published
publisher: EP Systema
publist_id: '2978'
status: public
title: The percolation interpretation of the nuclear fragmentation phase transition
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2986'
abstract:
- lang: eng
text: Long-standing models propose that plant growth responses to light or gravity
are mediated by asymmetric distribution of the phytohormone auxin. Physiological
studies implicated a specific transport system that relocates auxin laterally,
thereby effecting differential growth; however, neither the molecular components
of this system nor the cellular mechanism of auxin redistribution on light or
gravity perception have been identified. Here, we show that auxin accumulates
asymmetrically during differential growth in an efflux-dependent manner. Mutations
in the Arabidopsis gene PIN3, a regulator of auxin efflux, alter differential
growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating
predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane
and to vesicles that cycle in an actin-dependent manner. In the root columella,
PIN3 is positioned symmetrically at the plasma membrane but rapidly relocalizes
laterally on gravity stimulation. Our data indicate that PIN3 is a component of
the lateral auxin transport system regulating tropic growth. In addition, actin-dependent
relocalization of PIN3 in response to gravity provides a mechanism for redirecting
auxin flux to trigger asymmetric growth.
acknowledgement: We thank G. Jürgens for enabling J.F. to accomplish part of this
work in his laboratory; P. Tänzler and M. Sauer for technical assistance; H. Vahlenkamp
for technical assistance in immunocytochemistry; M. Estelle for providing material
and suggestions; T. Altman for BAC filter sets; the ADIS (Automated DNA Isolation
and Sequencing) service group for DNA sequencing; ZIGIA (Center for Functional Genomics
in Arabidopsis) for the En lines; and N. Geldner, T. Hamann, G. Jürgens, K. Schrick
and C. Schwechheimer for comments and critical reading of the manuscript. This work
was supported by a fellowship of the DAAD (J.F.), the DFG (Schwerpunktprogramm Phytohormone),
the Fonds der chemischen Industrie, the European Communities Biotechnology Programs,
the INCO-Copernicus Program and the European Space Agency MAP-Biotechnology Programme
article_processing_charge: No
article_type: original
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Justyna
full_name: Wiśniewska, Justyna
last_name: Wiśniewska
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Kurt
full_name: Mendgen, Kurt
last_name: Mendgen
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
citation:
ama: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. Lateral relocation of
auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 2002;415(6873):806-809.
doi:10.1038/415806a
apa: Friml, J., Wiśniewska, J., Benková, E., Mendgen, K., & Palme, K. (2002).
Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis.
Nature. Nature Publishing Group. https://doi.org/10.1038/415806a
chicago: Friml, Jiří, Justyna Wiśniewska, Eva Benková, Kurt Mendgen, and Klaus Palme.
“Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.”
Nature. Nature Publishing Group, 2002. https://doi.org/10.1038/415806a.
ieee: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, and K. Palme, “Lateral relocation
of auxin efflux regulator PIN3 mediates tropism in Arabidopsis,” Nature,
vol. 415, no. 6873. Nature Publishing Group, pp. 806–809, 2002.
ista: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. 2002. Lateral relocation
of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 415(6873),
806–809.
mla: Friml, Jiří, et al. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates
Tropism in Arabidopsis.” Nature, vol. 415, no. 6873, Nature Publishing
Group, 2002, pp. 806–09, doi:10.1038/415806a.
short: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, K. Palme, Nature 415 (2002)
806–809.
date_created: 2018-12-11T12:00:42Z
date_published: 2002-02-14T00:00:00Z
date_updated: 2023-07-18T07:30:27Z
day: '14'
doi: 10.1038/415806a
extern: '1'
external_id:
pmid:
- '11845211 '
intvolume: ' 415'
issue: '6873'
language:
- iso: eng
month: '02'
oa_version: None
page: 806 - 809
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '3715'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 415
year: '2002'
...
---
_id: '2987'
abstract:
- lang: eng
text: The hydra mutants of Arabidopsis are characterized by a pleiotropic phenotype
that shows defective embryonic and seedling cell patterning, morphogenesis, and
root growth. We demonstrate that the HYDRA1 gene encodes a Δ8-Δ7 sterol isomerase,
whereas HYDRA2 encodes a sterol C14 reductase, previously identified as the FACKEL
gene product. Seedlings mutant for each gene are similarly defective in the concentrations
of the three major Arabidopsis sterols. Promoter::reporter gene analysis showed
misexpression of the auxin-regulated DR5 and ACS1 promoters and of the epidermal
cell file-specific GL2 promoter in the mutants. The mutants exhibit enhanced responses
to auxin. The phenotypes can be rescued partially by inhibition of auxin and ethylene
signaling but not by exogenous sterols or brassinosteroids. We propose a model
in which correct sterol profiles are required for regulated auxin and ethylene
signaling through effects on membrane function.
acknowledgement: We thank Dr. Ken Feldmann for providing prospective hyd alleles,
Dr. Jane Murfett for providing DR5::GUS seed, Dr. D. Van Der Straeten for providing
ACS1::GUS seed, Dr. John Schiefelbein for providing GL2::GFP seed, and Dr. Ottoline
Leyser for axr1-12 and axr3-1 seed. etr1 and fk seed was obtained from the Nottingham
Arabidopsis Stock Centre. This work was supported by a Biotechnology and Biological
Science Research Council research studentship to M.S., a Durham University studentship
to M.P., and Biotechnology and Biological Science Research Council Grant 12/P02330
to J.T.
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Souter, Martin
last_name: Souter
- first_name: Jennifer
full_name: Topping, Jennifer
last_name: Topping
- first_name: Margaret
full_name: Pullen, Margaret
last_name: Pullen
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Rachel
full_name: Hackett, Rachel
last_name: Hackett
- first_name: Don
full_name: Grierson, Don
last_name: Grierson
- first_name: Keith
full_name: Lindsey, Keith
last_name: Lindsey
citation:
ama: Souter M, Topping J, Pullen M, et al. Hydra mutants of Arabidopsis are defective
in sterol profiles and auxin and ethylene signaling. Plant Cell. 2002;14(5):1017-1031.
doi:10.1105/tpc.001248
apa: Souter, M., Topping, J., Pullen, M., Friml, J., Palme, K., Hackett, R., … Lindsey,
K. (2002). Hydra mutants of Arabidopsis are defective in sterol profiles and auxin
and ethylene signaling. Plant Cell. American Society of Plant Biologists.
https://doi.org/10.1105/tpc.001248
chicago: Souter, Martin, Jennifer Topping, Margaret Pullen, Jiří Friml, Klaus Palme,
Rachel Hackett, Don Grierson, and Keith Lindsey. “Hydra Mutants of Arabidopsis
Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” Plant Cell.
American Society of Plant Biologists, 2002. https://doi.org/10.1105/tpc.001248.
ieee: M. Souter et al., “Hydra mutants of Arabidopsis are defective in sterol
profiles and auxin and ethylene signaling,” Plant Cell, vol. 14, no. 5.
American Society of Plant Biologists, pp. 1017–1031, 2002.
ista: Souter M, Topping J, Pullen M, Friml J, Palme K, Hackett R, Grierson D, Lindsey
K. 2002. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin
and ethylene signaling. Plant Cell. 14(5), 1017–1031.
mla: Souter, Martin, et al. “Hydra Mutants of Arabidopsis Are Defective in Sterol
Profiles and Auxin and Ethylene Signaling.” Plant Cell, vol. 14, no. 5,
American Society of Plant Biologists, 2002, pp. 1017–31, doi:10.1105/tpc.001248.
short: M. Souter, J. Topping, M. Pullen, J. Friml, K. Palme, R. Hackett, D. Grierson,
K. Lindsey, Plant Cell 14 (2002) 1017–1031.
date_created: 2018-12-11T12:00:42Z
date_published: 2002-05-01T00:00:00Z
date_updated: 2023-07-18T07:34:32Z
day: '01'
doi: 10.1105/tpc.001248
extern: '1'
external_id:
pmid:
- '12034894'
intvolume: ' 14'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150604/
month: '05'
oa: 1
oa_version: None
page: 1017 - 1031
pmid: 1
publication: Plant Cell
publication_identifier:
issn:
- 1040-4651
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3716'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and
ethylene signaling
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 14
year: '2002'
...
---
_id: '2866'
abstract:
- lang: eng
text: 'Developmental responses to the plant hormone auxin are thought to be mediated
by interacting pairs from two protein families: short-lived inhibitory IAA proteins
and ARF transcription factors binding to auxin-response elements. Monopteros mutants
lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate
the root meristem during early embryogenesis. Here we show that the bodenlos phenotype
results from an amino-acid exchange in the conserved degradation domain of IAA12.
BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes
are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS
action in root meristem initiation.'
acknowledgement: "We thank C. Maulbetsch for isolating BDL cDNA clones; T. Berleth
and J. Friml for providing clones for in situ probes; K. Harter for making available
the parsley protoplast system; and J. Friml, N. Geldner, M. Griffith, C. Schwechheimer,
D. Weigel, and D. Weijers for helpful comments and critical reading of the manuscript.
This work was supported by Sonderforschungsbereich 446 “Mechanismen des Zellverhaltens
bei Eukaryoten.”\r\n\r\nThe publication costs of this article were defrayed in part
by payment of page charges. This article must therefore be hereby marked “advertisement”
in accordance with 18 USC section 1734 solely to indicate this fact."
article_processing_charge: No
article_type: original
author:
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Isabel
full_name: Bäurle, Isabel
last_name: Bäurle
- first_name: Marika
full_name: Kientz, Marika
last_name: Kientz
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
citation:
ama: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. The Arabidopsis BODENLOS
gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning.
Genes and Development. 2002;16(13):1610-1615. doi:10.1101/gad.229402
apa: Hamann, T., Benková, E., Bäurle, I., Kientz, M., & Jürgens, G. (2002).
The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning. Genes and Development. Cold Spring Harbor Laboratory
Press. https://doi.org/10.1101/gad.229402
chicago: Hamann, Thorsten, Eva Benková, Isabel Bäurle, Marika Kientz, and Gerd Jürgens.
“The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated
Embryo Patterning.” Genes and Development. Cold Spring Harbor Laboratory
Press, 2002. https://doi.org/10.1101/gad.229402.
ieee: T. Hamann, E. Benková, I. Bäurle, M. Kientz, and G. Jürgens, “The Arabidopsis
BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning,” Genes and Development, vol. 16, no. 13. Cold Spring
Harbor Laboratory Press, pp. 1610–1615, 2002.
ista: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. 2002. The Arabidopsis
BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning. Genes and Development. 16(13), 1610–1615.
mla: Hamann, Thorsten, et al. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response
Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” Genes and Development,
vol. 16, no. 13, Cold Spring Harbor Laboratory Press, 2002, pp. 1610–15, doi:10.1101/gad.229402.
short: T. Hamann, E. Benková, I. Bäurle, M. Kientz, G. Jürgens, Genes and Development
16 (2002) 1610–1615.
date_created: 2018-12-11T12:00:01Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2023-07-18T08:26:58Z
day: '01'
doi: 10.1101/gad.229402
extern: '1'
external_id:
pmid:
- '12101120'
intvolume: ' 16'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC186366/
month: '07'
oa: 1
oa_version: Published Version
page: 1610 - 1615
pmid: 1
publication: Genes and Development
publication_identifier:
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '3921'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting
MONOPTEROS-mediated embryo patterning
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 16
year: '2002'
...
---
_id: '2927'
abstract:
- lang: eng
text: 'In the last few years, several new algorithms based on graph cuts have been
developed to solve energy minimization problems in computer vision. Each of these
techniques constructs a graph such that the minimum cut on the graph also minimizes
the energy. Yet because these graph constructions are complex and highly specific
to a particular energy function, graph cuts have seen limited application to date.
In this paper we characterize the energy functions that can be minimized by graph
cuts. Our results are restricted to energy functions with binary variables. However,
our work generalizes many previous constructions, and is easily applicable to
vision problems that involve large numbers of labels, such as stereo, motion,
image restoration and scene reconstruction. We present three main results: a necessary
condition for any energy function that can be minimized by graph cuts; a sufficient
condition for energy functions that can be written as a sum of functions of up
to three variables at a time; and a general-purpose construction to minimize such
an energy function. Researchers who are considering the use of graph cuts to optimize
a particular energy function can use our results to determine if this is possible,
and then follow our construction to create the appropriate graph.'
acknowledgement: We thank Olga Veksler and Yuri Boykov for their careful reading of
this paper, and for valuable comments which greatly improved itsreadibility. We
also thank Ian Jermyn for helping us clarify the paper’s motivation. This research
was supported by NSF grants IIS-9900115 and CCR-0113371, and by a grant from Microsoft
Research.
article_processing_charge: No
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Ramin
full_name: Zabih, Ramin
last_name: Zabih
citation:
ama: 'Kolmogorov V, Zabih R. Multi-camera scene reconstruction via graph cuts. In:
Proceedings of the 7th European Conference on Computer Vision. Springer;
2002:65-81. doi:10.1007/3-540-47977-5_5'
apa: 'Kolmogorov, V., & Zabih, R. (2002). Multi-camera scene reconstruction
via graph cuts. In Proceedings of the 7th European Conference on Computer Vision
(pp. 65–81). Copenhagen, Denmark: Springer. https://doi.org/10.1007/3-540-47977-5_5'
chicago: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction
via Graph Cuts.” In Proceedings of the 7th European Conference on Computer
Vision, 65–81. Springer, 2002. https://doi.org/10.1007/3-540-47977-5_5.
ieee: V. Kolmogorov and R. Zabih, “Multi-camera scene reconstruction via graph cuts,”
in Proceedings of the 7th European Conference on Computer Vision, Copenhagen,
Denmark, 2002, pp. 65–81.
ista: 'Kolmogorov V, Zabih R. 2002. Multi-camera scene reconstruction via graph
cuts. Proceedings of the 7th European Conference on Computer Vision. ECCV: European
Conference on Computer Vision, 65–81.'
mla: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via
Graph Cuts.” Proceedings of the 7th European Conference on Computer Vision,
Springer, 2002, pp. 65–81, doi:10.1007/3-540-47977-5_5.
short: V. Kolmogorov, R. Zabih, in:, Proceedings of the 7th European Conference
on Computer Vision, Springer, 2002, pp. 65–81.
conference:
end_date: 2002-05-31
location: Copenhagen, Denmark
name: 'ECCV: European Conference on Computer Vision'
start_date: 2002-05-28
date_created: 2018-12-11T12:00:23Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T08:20:02Z
day: '01'
doi: 10.1007/3-540-47977-5_5
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 65 - 81
publication: Proceedings of the 7th European Conference on Computer Vision
publication_identifier:
isbn:
- '9783540437468'
publication_status: published
publisher: Springer
publist_id: '3810'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multi-camera scene reconstruction via graph cuts
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2739'
abstract:
- lang: eng
text: We define the two dimensional Pauli operator and identify its core for magnetic
fields that are regular Borel measures. The magnetic field is generated by a scalar
potential hence we bypass the usual A L 2loc condition on the vector potential,
which does not allow to consider such singular fields. We extend the Aharonov-Casher
theorem for magnetic fields that are measures with finite total variation and
we present a counterexample in case of infinite total variation. One of the key
technical tools is a weighted L 2 estimate on a singular integral operator.
acknowledgement: "This work started during the first author’s visit at the Erwin Schrödinger
Institute, Vienna.\r\nValuable discussions with T. Hoffmann-Ostenhof and M. Loss
are gratefully acknowledged. The authors thank\r\nthe referee for careful reading
and comments"
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Vitali
full_name: Vougalter, Vitali
last_name: Vougalter
citation:
ama: Erdös L, Vougalter V. Pauli operator and Aharonov–Casher theorem¶ for measure
valued magnetic fields. Communications in Mathematical Physics. 2002;225(2):399-421.
doi:10.1007/s002200100585
apa: Erdös, L., & Vougalter, V. (2002). Pauli operator and Aharonov–Casher theorem¶
for measure valued magnetic fields. Communications in Mathematical Physics.
Springer. https://doi.org/10.1007/s002200100585
chicago: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher
Theorem¶ for Measure Valued Magnetic Fields.” Communications in Mathematical
Physics. Springer, 2002. https://doi.org/10.1007/s002200100585.
ieee: L. Erdös and V. Vougalter, “Pauli operator and Aharonov–Casher theorem¶ for
measure valued magnetic fields,” Communications in Mathematical Physics,
vol. 225, no. 2. Springer, pp. 399–421, 2002.
ista: Erdös L, Vougalter V. 2002. Pauli operator and Aharonov–Casher theorem¶ for
measure valued magnetic fields. Communications in Mathematical Physics. 225(2),
399–421.
mla: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶
for Measure Valued Magnetic Fields.” Communications in Mathematical Physics,
vol. 225, no. 2, Springer, 2002, pp. 399–421, doi:10.1007/s002200100585.
short: L. Erdös, V. Vougalter, Communications in Mathematical Physics 225 (2002)
399–421.
date_created: 2018-12-11T11:59:21Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-07-18T08:57:54Z
day: '01'
doi: 10.1007/s002200100585
extern: '1'
external_id:
arxiv:
- math-ph/0109015v1
intvolume: ' 225'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 399 - 421
publication: Communications in Mathematical Physics
publication_identifier:
issn:
- 0010-3616
publication_status: published
publisher: Springer
publist_id: '4153'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 225
year: '2002'
...
---
_id: '2738'
abstract:
- lang: eng
text: We consider the long time evolution of a quantum particle weakly interacting
with a phonon field. We show that in the weak coupling limit the Wigner distribution
of the electron density matrix converges to the solution of the linear Boltzmann
equation globally in time. The collision kernel is identified as the sum of an
emission and an absorption term that depend on the equilibrium distribution of
the free phonon modes.
acknowledgement: "This work initially was a joint project with H.-T. Yau and several
ideas\r\npresented here have been developed in collaboration with him. I would like\r\nto
thank him for the invaluable discussions and encouragement through\r\nthe entire
work. Part of this project was completed during several visits at\r\nthe Erwin Schrödinger
Institute, Vienna, and at the Center of Theoretical\r\nStudies, Hsinchu, Taiwan.
The author is grateful for the hospitality and\r\nfinancial support. This work was
partially supported by NSF Grant DMS9970323."
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Erdös L. Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field. Journal of Statistical Physics. 2002;107(5-6):1043-1127.
doi:10.1023/A:1015157624384
apa: Erdös, L. (2002). Linear Boltzmann equation as the long time dynamics of an
electron weakly coupled to a phonon field. Journal of Statistical Physics.
Springer. https://doi.org/10.1023/A:1015157624384
chicago: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of
an Electron Weakly Coupled to a Phonon Field.” Journal of Statistical Physics.
Springer, 2002. https://doi.org/10.1023/A:1015157624384.
ieee: L. Erdös, “Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field,” Journal of Statistical Physics, vol.
107, no. 5–6. Springer, pp. 1043–1127, 2002.
ista: Erdös L. 2002. Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field. Journal of Statistical Physics. 107(5–6), 1043–1127.
mla: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of an Electron
Weakly Coupled to a Phonon Field.” Journal of Statistical Physics, vol.
107, no. 5–6, Springer, 2002, pp. 1043–127, doi:10.1023/A:1015157624384.
short: L. Erdös, Journal of Statistical Physics 107 (2002) 1043–1127.
date_created: 2018-12-11T11:59:20Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-18T09:08:45Z
day: '01'
doi: 10.1023/A:1015157624384
extern: '1'
external_id:
arxiv:
- math-ph/0108025
intvolume: ' 107'
issue: 5-6
language:
- iso: eng
month: '06'
oa_version: Submitted Version
page: 1043 - 1127
publication: Journal of Statistical Physics
publication_identifier:
issn:
- 0022-4715
publication_status: published
publisher: Springer
publist_id: '4154'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Linear Boltzmann equation as the long time dynamics of an electron weakly coupled
to a phonon field
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 107
year: '2002'
...
---
_id: '2740'
abstract:
- lang: eng
text: We show that the lowest eigenvalue of the magnetic Schrödinger operator on
a line bundle over a compact Riemann surface M is bounded by the L1-norm of the
magnetic field B. This implies a similar bound on the multiplicity of the ground
state. An example shows that this degeneracy can indeed be comparable with ∫M
|B| even in case of the trivial bundle.
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Erdös L. Spectral shift and multiplicity of the first eigenvalue of the magnetic
Schrödinger operator in two dimensions. Annales de l’Institut Fourier.
2002;52(6):1833-1874. doi:10.5802/aif.1936
apa: Erdös, L. (2002). Spectral shift and multiplicity of the first eigenvalue of
the magnetic Schrödinger operator in two dimensions. Annales de l’Institut
Fourier. Association des Annales de l’Institut Fourier. https://doi.org/10.5802/aif.1936
chicago: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue
of the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut
Fourier. Association des Annales de l’Institut Fourier, 2002. https://doi.org/10.5802/aif.1936.
ieee: L. Erdös, “Spectral shift and multiplicity of the first eigenvalue of the
magnetic Schrödinger operator in two dimensions,” Annales de l’Institut Fourier,
vol. 52, no. 6. Association des Annales de l’Institut Fourier, pp. 1833–1874,
2002.
ista: Erdös L. 2002. Spectral shift and multiplicity of the first eigenvalue of
the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier.
52(6), 1833–1874.
mla: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of
the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut
Fourier, vol. 52, no. 6, Association des Annales de l’Institut Fourier, 2002,
pp. 1833–74, doi:10.5802/aif.1936.
short: L. Erdös, Annales de l’Institut Fourier 52 (2002) 1833–1874.
date_created: 2018-12-11T11:59:21Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T08:38:34Z
day: '01'
doi: 10.5802/aif.1936
extern: '1'
intvolume: ' 52'
issue: '6'
language:
- iso: eng
month: '01'
oa_version: None
page: 1833-1874
publication: Annales de l'Institut Fourier
publication_identifier:
issn:
- 0373-0956
publication_status: published
publisher: Association des Annales de l'Institut Fourier
publist_id: '4152'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger
operator in two dimensions
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '2002'
...
---
_id: '2737'
abstract:
- lang: eng
text: We derive the time-dependent Schrödinger–Poisson equation as the weak coupling
limit of the N-body linear Schrödinger equation with Coulomb potential.
acknowledgement: "The authors thank the ESI in Vienna and the Austrian START project
“Nonlinear Schrödinger\r\nand quantum Boltzmann equations” of N.J.M. for hospitality
and support. Also, F.G. was supported by the Institut\r\nUniversitaire de France
and N.J.M. by the bilateral Austrian-French “AMADEUS” programme. H.-T.Y. and L.E.
were\r\nsupported by NSF Grants DMS-0072098 and DMS-9970323, respectively"
article_processing_charge: No
article_type: original
author:
- first_name: Claude
full_name: Bardos, Claude
last_name: Bardos
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: François
full_name: Golse, François
last_name: Golse
- first_name: Norbert
full_name: Mauser, Norbert
last_name: Mauser
- first_name: Horng
full_name: Yau, Horng
last_name: Yau
citation:
ama: Bardos C, Erdös L, Golse F, Mauser N, Yau H. Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem. Comptes Rendus Mathematique.
2002;334(6):515-520. doi:10.1016/S1631-073X(02)02253-7
apa: Bardos, C., Erdös, L., Golse, F., Mauser, N., & Yau, H. (2002). Derivation
of the Schrödinger-Poisson equation from the quantum N-body problem. Comptes
Rendus Mathematique. Elsevier. https://doi.org/10.1016/S1631-073X(02)02253-7
chicago: Bardos, Claude, László Erdös, François Golse, Norbert Mauser, and Horng
Yau. “Derivation of the Schrödinger-Poisson Equation from the Quantum N-Body Problem.”
Comptes Rendus Mathematique. Elsevier, 2002. https://doi.org/10.1016/S1631-073X(02)02253-7.
ieee: C. Bardos, L. Erdös, F. Golse, N. Mauser, and H. Yau, “Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem,” Comptes Rendus Mathematique,
vol. 334, no. 6. Elsevier, pp. 515–520, 2002.
ista: Bardos C, Erdös L, Golse F, Mauser N, Yau H. 2002. Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem. Comptes Rendus Mathematique. 334(6),
515–520.
mla: Bardos, Claude, et al. “Derivation of the Schrödinger-Poisson Equation from
the Quantum N-Body Problem.” Comptes Rendus Mathematique, vol. 334, no.
6, Elsevier, 2002, pp. 515–20, doi:10.1016/S1631-073X(02)02253-7.
short: C. Bardos, L. Erdös, F. Golse, N. Mauser, H. Yau, Comptes Rendus Mathematique
334 (2002) 515–520.
date_created: 2018-12-11T11:59:20Z
date_published: 2002-03-30T00:00:00Z
date_updated: 2023-07-18T09:24:24Z
day: '30'
doi: 10.1016/S1631-073X(02)02253-7
extern: '1'
intvolume: ' 334'
issue: '6'
language:
- iso: eng
month: '03'
oa_version: None
page: 515 - 520
publication: Comptes Rendus Mathematique
publication_identifier:
issn:
- 1631-073X
publication_status: published
publisher: Elsevier
publist_id: '4155'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Derivation of the Schrödinger-Poisson equation from the quantum N-body problem
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 334
year: '2002'
...
---
_id: '2624'
abstract:
- lang: eng
text: Metabotropic γ-aminobutyric acid receptors (GABABRs) are involved in modulation
of synaptic transmission and activity of cerebellar and thalamic neurons. We used
subtype-specific antibodies in pre- and postembedding immunohistochemistry combined
with three-dimensional reconstruction of labelled profiles and quantification
of immunoparticles to reveal the subcellular distribution of pre- and postsynaptic
GABABR1a/b and GABABR2 in the rat cerebellum and ventrobasal thalamus. GABABR1a/b
and R2 were extensively colocalized in most brain regions including the cerebellum
and thalamus. In the cerebellum, immunoreactivity for both subtypes was prevalent
in the molecular layer. The most intense immunoreactivity was found in Purkinje
cell spines with a high density of immunoparticles at extrasynaptic sites peaking
at around 240 nm from glutamatergic synapses between spines and parallel fibre
varicosities. This is in contrast to dendrites at sites around GABAergic synapses
where sparse and random distribution was found for both subtypes. In addition,
more than one-tenth of the synaptic membrane specialization of spine-parallel
fibre synapses were labelled at pre- or postsynaptic sites. Weak immunolabelling
for both subtypes was also seen in parallel fibres but only rarely in GABAergic
axons. In the ventrobasal thalamus, immunolabelling for both receptor subtypes
was intense over the dendritic field of thalamocortical cells. Electron microscopy
demonstrated an extrasynaptic localization of GABABR1a/b and R2 exclusively in
postsynaptic elements. Quantitative analysis further revealed the density of GABABR1a/b
around GABAergic synapses was higher than glutamatergic synapses on thalamocortical
cell dendrites. The distinct localization of GABABRs relative to synaptic sites
in the cerebellum and ventrobasal thalamus suggests that GABABRs differentially
regulate activity of different neuronal populations.
acknowledgement: This work was supported by research grants from the Ministry of Education,
Science, Sports and Culture of Japan, and the Japan Society for the Promotion of
Science (P96319). We thank Drs L. Zaborszky and R. Luján for their comments on the
manuscript, Dr M. Watanabe for kindly supplying us with GluRδ2 and AMPA GluR1 antibodies,
Dr R.E. Edwards for rabbit BNPI antibody, and J. Hatakeyama and S. Doi for technical
assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Kazuhiko
full_name: Nakadate, Kazuhiko
last_name: Nakadate
- first_name: Gábor
full_name: Nyíri, Gábor
last_name: Nyíri
- first_name: Takuya
full_name: Notomi, Takuya
last_name: Notomi
- first_name: Barbara
full_name: Malitschek, Barbara
last_name: Malitschek
- first_name: Bernhard
full_name: Bettler, Bernhard
last_name: Bettler
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Kulik Á, Nakadate K, Nyíri G, et al. Distinct localization of GABAB receptors
relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. European
Journal of Neuroscience. 2002;15(2):291-307. doi:10.1046/j.0953-816x.2001.01855.x
apa: Kulik, Á., Nakadate, K., Nyíri, G., Notomi, T., Malitschek, B., Bettler, B.,
& Shigemoto, R. (2002). Distinct localization of GABAB receptors relative
to synaptic sites in the rat cerebellum and ventrobasal thalamus. European
Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.0953-816x.2001.01855.x
chicago: Kulik, Ákos, Kazuhiko Nakadate, Gábor Nyíri, Takuya Notomi, Barbara Malitschek,
Bernhard Bettler, and Ryuichi Shigemoto. “Distinct Localization of GABAB Receptors
Relative to Synaptic Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European
Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.0953-816x.2001.01855.x.
ieee: Á. Kulik et al., “Distinct localization of GABAB receptors relative
to synaptic sites in the rat cerebellum and ventrobasal thalamus,” European
Journal of Neuroscience, vol. 15, no. 2. Wiley-Blackwell, pp. 291–307, 2002.
ista: Kulik Á, Nakadate K, Nyíri G, Notomi T, Malitschek B, Bettler B, Shigemoto
R. 2002. Distinct localization of GABAB receptors relative to synaptic sites in
the rat cerebellum and ventrobasal thalamus. European Journal of Neuroscience.
15(2), 291–307.
mla: Kulik, Ákos, et al. “Distinct Localization of GABAB Receptors Relative to Synaptic
Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European Journal of
Neuroscience, vol. 15, no. 2, Wiley-Blackwell, 2002, pp. 291–307, doi:10.1046/j.0953-816x.2001.01855.x.
short: Á. Kulik, K. Nakadate, G. Nyíri, T. Notomi, B. Malitschek, B. Bettler, R.
Shigemoto, European Journal of Neuroscience 15 (2002) 291–307.
date_created: 2018-12-11T11:58:44Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T13:08:40Z
day: '01'
doi: 10.1046/j.0953-816x.2001.01855.x
extern: '1'
external_id:
pmid:
- '11849296'
intvolume: ' 15'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 291 - 307
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
issn:
- 0953-816X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4275'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct localization of GABAB receptors relative to synaptic sites in the
rat cerebellum and ventrobasal thalamus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2002'
...
---
_id: '2694'
abstract:
- lang: eng
text: We outline the status of rigorous derivations of certain classical evolution
equations as limits of Schrödinger dynamics. We explain two recent results jointly
with H.T. Yau in more details. The first one is the derivation of the linear Boltzmann
equation as the long time limit of the one-body Schrödinger equation with a random
potential. The second one is the mean field limit of high density bosons with
Coulomb interaction that leads to the nonlinear Hartree equation.
alternative_title:
- LNP
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: 'Erdös L. Scaling limits of Schrödinger quantum mechanics. In: Dynamics
of Dissipation. Lecture Notes in Physics. Springer; 2002:487-506. doi:10.1007/3-540-46122-1_19'
apa: Erdös, L. (2002). Scaling limits of Schrödinger quantum mechanics. In Dynamics
of Dissipation (pp. 487–506). Springer. https://doi.org/10.1007/3-540-46122-1_19
chicago: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” In Dynamics
of Dissipation, 487–506. Lecture Notes in Physics. Springer, 2002. https://doi.org/10.1007/3-540-46122-1_19.
ieee: L. Erdös, “Scaling limits of Schrödinger quantum mechanics,” in Dynamics
of Dissipation, Springer, 2002, pp. 487–506.
ista: 'Erdös L. 2002.Scaling limits of Schrödinger quantum mechanics. In: Dynamics
of Dissipation. LNP, , 487–506.'
mla: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” Dynamics
of Dissipation, Springer, 2002, pp. 487–506, doi:10.1007/3-540-46122-1_19.
short: L. Erdös, in:, Dynamics of Dissipation, Springer, 2002, pp. 487–506.
conference:
name: '38th Winter School of Theoretical Physics : Dynamical Semigroups: Dissipation,
Chaos, Quanta'
date_created: 2018-12-11T11:59:06Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T10:23:18Z
day: '01'
doi: 10.1007/3-540-46122-1_19
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 487 - 506
publication: Dynamics of Dissipation
publication_identifier:
isbn:
- '9783540441113'
publication_status: published
publisher: Springer
publist_id: '4203'
quality_controlled: '1'
series_title: Lecture Notes in Physics
status: public
title: Scaling limits of Schrödinger quantum mechanics
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2622'
abstract:
- lang: eng
text: To understand the possible contribution of metabotropic γ-aminobutyric acid
receptors (GABABR) in cortical development, we investigated the expression pattern
and the cellular and subcellular localization of the GABABR1 and GABABR2 subtypes
in the rat neocortex from embryonic day 14 (E14) to adulthood. At the light microscopic
level, both GABABR1 and GABABR2 were detected as early as E14. During prenatal
development, both subtypes were expressed highly in the cortical plate. Using
double immunofluorescence, GABABR1 colocalized with GABABR2 in neurons of the
marginal zone and subplate, indicating that these proteins are coexpressed and
could be forming functional GABABRs during prenatal development in vivo. In contrast,
only GABABR1 but not GABABR2 was detected in the tangentially migratory cells
in the lower intermediate zone. During postnatal development, immunoreactivity
for GABABR1 and GABABR2 was distributed mainly in pyramidal cells. Discrete GABABR1-immunopositive
cell bodies of interneurons were present throughout the neocortex. In addition,
GABABR1 but not GABABR2 was found in identified Cajal-Retzius cells in layer I.
At the electron microscopic level, immunoreactivity for GABABR1 and GABABR2 was
found in dendritic spines and dendritic shafts at extrasynaptic and perisynaptic
sites throughout postnatal development. We further demonstrated the presynaptic
localization of GABABR1 and GABABR2, as well as the association of the receptors
with asymmetrical synaptic junctions. These results indicate potentially important
roles for the GABABRs in the regulation of migratory processes during corticogenesis
and in the modulation of synaptic transmission during early development of cortical
circuitry.
acknowledgement: The authors are grateful to Dr Marco Sassoe-Pogneto for his comments
on a previous version of the manuscript. We also would like to thank to Ms. Courtney
Voelker for the English revision and comments of the manuscript. This work was made
possible by grants from the European Community (QLG3-CT-1999–00192, R.L) and the
Spanish Ministry of Science and Technology (PB97-0582-CO2-01, A.F).
article_processing_charge: No
article_type: original
author:
- first_name: Guillermina
full_name: López Bendito, Guillermina
last_name: López Bendito
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Ole
full_name: Paulsen, Ole
last_name: Paulsen
- first_name: Alfonso
full_name: Fairén, Alfonso
last_name: Fairén
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
citation:
ama: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. Expression
and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during
rat neocortical development. European Journal of Neuroscience. 2002;15(11):1766-1778.
doi:10.1046/j.1460-9568.2002.02032.x
apa: López Bendito, G., Shigemoto, R., Kulik, Á., Paulsen, O., Fairén, A., &
Luján, R. (2002). Expression and distribution of metabotropic GABA receptor subtypes
GABABR1 and GABABR2 during rat neocortical development. European Journal of
Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2002.02032.x
chicago: López Bendito, Guillermina, Ryuichi Shigemoto, Ákos Kulik, Ole Paulsen,
Alfonso Fairén, and Rafael Luján. “Expression and Distribution of Metabotropic
GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.”
European Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.1460-9568.2002.02032.x.
ieee: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, and R. Luján,
“Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and
GABABR2 during rat neocortical development,” European Journal of Neuroscience,
vol. 15, no. 11. Wiley-Blackwell, pp. 1766–1778, 2002.
ista: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. 2002.
Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and
GABABR2 during rat neocortical development. European Journal of Neuroscience.
15(11), 1766–1778.
mla: López Bendito, Guillermina, et al. “Expression and Distribution of Metabotropic
GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.”
European Journal of Neuroscience, vol. 15, no. 11, Wiley-Blackwell, 2002,
pp. 1766–78, doi:10.1046/j.1460-9568.2002.02032.x.
short: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, R. Luján,
European Journal of Neuroscience 15 (2002) 1766–1778.
date_created: 2018-12-11T11:58:43Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-19T07:30:39Z
day: '01'
doi: 10.1046/j.1460-9568.2002.02032.x
extern: '1'
external_id:
pmid:
- '12081656'
intvolume: ' 15'
issue: '11'
language:
- iso: eng
month: '06'
oa_version: None
page: 1766 - 1778
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
issn:
- 0953-816X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4276'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expression and distribution of metabotropic GABA receptor subtypes GABABR1
and GABABR2 during rat neocortical development
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2002'
...
---
_id: '2621'
abstract:
- lang: eng
text: The release properties of glutamatergic nerve terminals are influenced by
a number of factors, including the subtype of voltage-dependent calcium channel
and the presence of presynaptic autoreceptors. Group III metabotropic glutamate
receptors (mGluRs) mediate feedback inhibition of glutamate release by inhibiting
Ca2+ channel activity. By imaging Ca2+ in preparations of cerebrocortical nerve
terminals, we show that voltage-dependent Ca2+ channels are distributed in a heterogeneous
manner in individual nerve terminals. Presynaptic terminals contained only N-type
(47.5%; conotoxin GVIA-sensitive), P/Q-type (3.9%; agatoxin IVA-sensitive), or
both N- and P/Q-type (42.6%) Ca2+ channels, although the remainder of the terminals
(6.1%) were insensitive to these two toxins. In this preparation, two mGluRs with
high and low affinity for L(+)-2-amino-4-phosphonobutyrate were identified by
immunocytochemistry as mGluR4 and mGluR7, respectively. These receptors were responsible
for 22.2 and 24.1% reduction of glutamate release, and they reduced the Ca2+ response
in 24.4 and 30.3% of the nerve terminals, respectively. Interestingly, mGluR4
was largely (73.7%) located in nerve terminals expressing both N- and P/Q-type
Ca2+ channels, whereas mGluR7 was predominantly (69.9%) located in N-type Ca2+
channel-expressing terminals. This specific coexpression of different group III
mGluRs and Ca2+ channels may endow synaptic terminals with distinct release properties
and reveals the existence of a high degree of presynaptic heterogeneity.
acknowledgement: We thank M. Sefton for editorial assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Carmelo
full_name: Millán, Carmelo
last_name: Millán
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: José
full_name: Sánchez Prieto, José
last_name: Sánchez Prieto
citation:
ama: Millán C, Luján R, Shigemoto R, Sánchez Prieto J. Subtype-specific expression
of Group III metabotropic glutamate receptors and Ca2+ channels in single nerve
terminals. Journal of Biological Chemistry. 2002;277(49):47796-47803. doi:10.1074/jbc.M207531200
apa: Millán, C., Luján, R., Shigemoto, R., & Sánchez Prieto, J. (2002). Subtype-specific
expression of Group III metabotropic glutamate receptors and Ca2+ channels in
single nerve terminals. Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M207531200
chicago: Millán, Carmelo, Rafael Luján, Ryuichi Shigemoto, and José Sánchez Prieto.
“Subtype-Specific Expression of Group III Metabotropic Glutamate Receptors and
Ca2+ Channels in Single Nerve Terminals.” Journal of Biological Chemistry.
American Society for Biochemistry and Molecular Biology, 2002. https://doi.org/10.1074/jbc.M207531200.
ieee: C. Millán, R. Luján, R. Shigemoto, and J. Sánchez Prieto, “Subtype-specific
expression of Group III metabotropic glutamate receptors and Ca2+ channels in
single nerve terminals,” Journal of Biological Chemistry, vol. 277, no.
49. American Society for Biochemistry and Molecular Biology, pp. 47796–47803,
2002.
ista: Millán C, Luján R, Shigemoto R, Sánchez Prieto J. 2002. Subtype-specific expression
of Group III metabotropic glutamate receptors and Ca2+ channels in single nerve
terminals. Journal of Biological Chemistry. 277(49), 47796–47803.
mla: Millán, Carmelo, et al. “Subtype-Specific Expression of Group III Metabotropic
Glutamate Receptors and Ca2+ Channels in Single Nerve Terminals.” Journal of
Biological Chemistry, vol. 277, no. 49, American Society for Biochemistry
and Molecular Biology, 2002, pp. 47796–803, doi:10.1074/jbc.M207531200.
short: C. Millán, R. Luján, R. Shigemoto, J. Sánchez Prieto, Journal of Biological
Chemistry 277 (2002) 47796–47803.
date_created: 2018-12-11T11:58:43Z
date_published: 2002-12-02T00:00:00Z
date_updated: 2023-07-19T07:49:19Z
day: '02'
doi: 10.1074/jbc.M207531200
extern: '1'
external_id:
pmid:
- '12376542'
intvolume: ' 277'
issue: '49'
language:
- iso: eng
month: '12'
oa_version: Published Version
page: 47796 - 47803
pmid: 1
publication: Journal of Biological Chemistry
publication_identifier:
issn:
- 0021-9258
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '4277'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Subtype-specific expression of Group III metabotropic glutamate receptors and
Ca2+ channels in single nerve terminals
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 277
year: '2002'
...
---
_id: '2620'
abstract:
- lang: eng
text: An ion channel's function depends largely on its location and density on neurons.
Here we used high-resolution immunolocalization to determine the subcellular distribution
of the hyperpolarization-activated and cyclic-nucleotide-gated channel subunit
1 (HCN1) in rat brain. Light microscopy revealed graded HCN1 immunoreactivity
in apical dendrites of hippocampal, subicular and neocortical layer-5 pyramidal
cells. Quantitative comparison of immunogold densities showed a 60-fold increase
from somatic to distal apical dendritic membranes. Distal dendritic shafts had
16 times more HCN1 labeling than proximal dendrites of similar diameters. At the
same distance from the soma, the density of HCN1 was significantly higher in dendritic
shafts than in spines. Our results reveal the complex cell surface distribution
of voltage-gated ion-channels, and predict its role in increasing the computational
power of single neurons via subcellular domain and input-specific mechanisms.
acknowledgement: Z.N. received grants from the Hungarian Science Foundation (T032309),
the Howard Hughes Medical Institute, the James S. McDonnell Foundation, the Wellcome
Trust and the Boehringer Ingelheim Fund. Z.N. and R.S. received grants from CREST—Japan
Science and Technology Corporation. G.T. is funded by the Wellcome Trust.
article_processing_charge: No
article_type: original
author:
- first_name: Andrea
full_name: Lörincz, Andrea
last_name: Lörincz
- first_name: Takuya
full_name: Notomi, Takuya
last_name: Notomi
- first_name: Gábor
full_name: Tamás, Gábor
last_name: Tamás
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Zoltán
full_name: Nusser, Zoltán
last_name: Nusser
citation:
ama: Lörincz A, Notomi T, Tamás G, Shigemoto R, Nusser Z. Polarized and compartment-dependent
distribution of HCN1 in pyramidal cell dendrites. Nature Neuroscience.
2002;5(11):1185-1193. doi:10.1038/nn962
apa: Lörincz, A., Notomi, T., Tamás, G., Shigemoto, R., & Nusser, Z. (2002).
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn962
chicago: Lörincz, Andrea, Takuya Notomi, Gábor Tamás, Ryuichi Shigemoto, and Zoltán
Nusser. “Polarized and Compartment-Dependent Distribution of HCN1 in Pyramidal
Cell Dendrites.” Nature Neuroscience. Nature Publishing Group, 2002. https://doi.org/10.1038/nn962.
ieee: A. Lörincz, T. Notomi, G. Tamás, R. Shigemoto, and Z. Nusser, “Polarized and
compartment-dependent distribution of HCN1 in pyramidal cell dendrites,” Nature
Neuroscience, vol. 5, no. 11. Nature Publishing Group, pp. 1185–1193, 2002.
ista: Lörincz A, Notomi T, Tamás G, Shigemoto R, Nusser Z. 2002. Polarized and compartment-dependent
distribution of HCN1 in pyramidal cell dendrites. Nature Neuroscience. 5(11),
1185–1193.
mla: Lörincz, Andrea, et al. “Polarized and Compartment-Dependent Distribution of
HCN1 in Pyramidal Cell Dendrites.” Nature Neuroscience, vol. 5, no. 11,
Nature Publishing Group, 2002, pp. 1185–93, doi:10.1038/nn962.
short: A. Lörincz, T. Notomi, G. Tamás, R. Shigemoto, Z. Nusser, Nature Neuroscience
5 (2002) 1185–1193.
date_created: 2018-12-11T11:58:43Z
date_published: 2002-11-01T00:00:00Z
date_updated: 2023-07-25T09:02:48Z
day: '01'
doi: 10.1038/nn962
extern: '1'
external_id:
pmid:
- '12389030'
intvolume: ' 5'
issue: '11'
language:
- iso: eng
month: '11'
oa_version: None
page: 1185 - 1193
pmid: 1
publication: Nature Neuroscience
publication_identifier:
issn:
- 1097-6256
publication_status: published
publisher: Nature Publishing Group
publist_id: '4278'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polarized and compartment-dependent distribution of HCN1 in pyramidal cell
dendrites
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 5
year: '2002'
...
---
_id: '2614'
abstract:
- lang: eng
text: Metabotropic glutamate receptors (mGluRs) from group III reduce glutamate
release. Because these receptors reduce cAMP levels, we explored whether this
signaling pathway contributes to release inhibition caused by mGluRs with low
affinity for L-2-amino-4-phosphonobutyrate (L-AP4). In biochemical experiments
with the population of cerebrocortical nerve terminals we find that L-AP4 (1 mM)
inhibited the Ca2+dependent-evoked release of glutamate by 25%. This inhibitory
effect was largely prevented by the pertussis toxin but was insensitive to inhibitors
of protein kinase C bisindolylmaleimide and protein kinase A H-89. Furthermore,
this inhibition was associated with reduction in N-type Ca2+ channel activity
in the absence of any detectable change in cAMP levels. In the presence of forskolin,
however, L-AP4 decreased the levels of cAMP. The activation of this additional
signaling pathway was very efficient in counteracting the facilitation of glutamate
release induced either by forskolin or the β-adrenergic receptor agonist isoproterenol.
Imaging experiments to measure Ca2+ dynamics in single nerve terminals showed
that L-AP4 strongly reduced the Ca2+ response in 28% of the nerve terminals. Moreover,
immunochemical experiments showed that 25-35% of the nerve terminals that were
immunopositive to synaptophysin were also immunoreactive to the low affinity L-AP4-sensitive
mGluR7. Then, mGluR7 mediates the inhibition of glutamate release caused by 1
mM L-AP4, primarily by a strong inhibition of Ca2+ channels, although high cAMP
uncovers the receptor ability to decrease cAMP.
acknowledgement: We thank Dr. Enrique Castro from Las Palmas University for critical
reading of the manuscript and M. Sefton for editorial assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Carmelo
full_name: Millán, Carmelo
last_name: Millán
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: José
full_name: Sánchez Prieto, José
last_name: Sánchez Prieto
citation:
ama: Millán C, Luján R, Shigemoto R, Sánchez Prieto J. The inhibition of glutamate
release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence
for a strong reduction of Ca2+ entry in single nerve terminals. Journal of
Biological Chemistry. 2002;277(16):14092-14101. doi:10.1074/jbc.M109044200
apa: Millán, C., Luján, R., Shigemoto, R., & Sánchez Prieto, J. (2002). The
inhibition of glutamate release by metabotropic glutamate receptor 7 affects both
[Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve
terminals. Journal of Biological Chemistry. American Society for Biochemistry
and Molecular Biology. https://doi.org/10.1074/jbc.M109044200
chicago: Millán, Carmelo, Rafael Luján, Ryuichi Shigemoto, and José Sánchez Prieto.
“The Inhibition of Glutamate Release by Metabotropic Glutamate Receptor 7 Affects
Both [Ca2+]c and CAMP. Evidence for a Strong Reduction of Ca2+ Entry in Single
Nerve Terminals.” Journal of Biological Chemistry. American Society for
Biochemistry and Molecular Biology, 2002. https://doi.org/10.1074/jbc.M109044200.
ieee: C. Millán, R. Luján, R. Shigemoto, and J. Sánchez Prieto, “The inhibition
of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c
and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals,”
Journal of Biological Chemistry, vol. 277, no. 16. American Society for
Biochemistry and Molecular Biology, pp. 14092–14101, 2002.
ista: Millán C, Luján R, Shigemoto R, Sánchez Prieto J. 2002. The inhibition of
glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and
cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals.
Journal of Biological Chemistry. 277(16), 14092–14101.
mla: Millán, Carmelo, et al. “The Inhibition of Glutamate Release by Metabotropic
Glutamate Receptor 7 Affects Both [Ca2+]c and CAMP. Evidence for a Strong Reduction
of Ca2+ Entry in Single Nerve Terminals.” Journal of Biological Chemistry,
vol. 277, no. 16, American Society for Biochemistry and Molecular Biology, 2002,
pp. 14092–101, doi:10.1074/jbc.M109044200.
short: C. Millán, R. Luján, R. Shigemoto, J. Sánchez Prieto, Journal of Biological
Chemistry 277 (2002) 14092–14101.
date_created: 2018-12-11T11:58:41Z
date_published: 2002-04-19T00:00:00Z
date_updated: 2023-07-25T10:16:44Z
day: '19'
ddc:
- '570'
doi: 10.1074/jbc.M109044200
extern: '1'
external_id:
pmid:
- '11825890'
file:
- access_level: open_access
checksum: 0290fcbbd9153ec654185b0c856f214c
content_type: application/pdf
creator: alisjak
date_created: 2023-07-25T10:13:16Z
date_updated: 2023-07-25T10:13:16Z
file_id: '13309'
file_name: 2002_JBC_Millan.pdf
file_size: 2105520
relation: main_file
success: 1
file_date_updated: 2023-07-25T10:13:16Z
has_accepted_license: '1'
intvolume: ' 277'
issue: '16'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 14092 - 14101
pmid: 1
publication: Journal of Biological Chemistry
publication_identifier:
issn:
- 0021-9258
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '4284'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The inhibition of glutamate release by metabotropic glutamate receptor 7 affects
both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve
terminals
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 277
year: '2002'
...
---
_id: '2613'
abstract:
- lang: eng
text: In this investigation, we report identification and characterization of a
95 kDa postsynaptic density protein (PSD-95)/discs-large/ ZO-1 (PDZ) domain-containing
protein termed tamalin, also recently named GRP1-associated scaffold protein (GRASP),
that interacts with group 1 metabotropic glutamate receptors (mGluRs). The yeast
two-hybrid system and in vitro pull-down assays indicated that the PDZ domain-containing,
amino-terminal half of tamalin directly binds to the class I PDZ-binding motif
of group 1 mGluRs. The C-terminal half of tamalin also bound to cytohesins, the
members of guanine nucleotide exchange factors (GEFs) specific for the ADP-ribosylation
factor (ARF) family of small GTP-binding proteins. Tamalin mRNA is expressed predominantly
in the telencephalic region and highly overlaps with the expression of group 1
mGluR mRNAs. Both tamalin and cytohesin-2 were enriched and codistributed with
mGluR1a in postsynaptic membrane fractions. Importantly, recombinant and native
mGluR1a/tamalin/cytohesin-2 complexes were coimmunoprecipitated from transfected
COS-7 cells and rat brain tissue, respectively. Transfection of tamalin and mutant
tamalin lacking a cytohesin-binding domain caused an increase and decrease in
cell-surface expression of mGluR1a in COS-7 cells, respectively. Furthermore,
adenovirus-mediated expression of tamalin and dominant-negative tamalin facilitated
and reduced the neuritic distribution of endogenous mGluR5 in cultured hippocampal
neurons, respectively. The results indicate that tamalin plays a key role in the
association of group 1 mGluRs with the ARF-specific GEF proteins and contributes
to intracellular trafficking and the macromolecular organization of group 1 mGluRs
at synapses.
acknowledgement: This work was supported in part by research grants from the Ministry
of Education, Science and Culture of Japan. We thank Bert Vogelstein for providing
adenoviral recombination vectors and Haruhiko Bito for a gift of the enolase promoter
and technical advice. We are grateful to Atsushi Nishimune and Satoshi Kaneko for
technical advice and Kumlesh K. Dev for careful reading of this manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Jun
full_name: Kitano, Jun
last_name: Kitano
- first_name: Kouji
full_name: Kimura, Kouji
last_name: Kimura
- first_name: Yoshimitsu
full_name: Yamazaki, Yoshimitsu
last_name: Yamazaki
- first_name: Takeshi
full_name: Soda, Takeshi
last_name: Soda
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Yoshiaki
full_name: Nakajima, Yoshiaki
last_name: Nakajima
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Kitano J, Kimura K, Yamazaki Y, et al. Tamalin, a PDZ domain-containing protein,
links a protein complex formation of group 1 metabotropic glutamate receptors
and the guanine nucleotide exchange factor cytohesins. Journal of Neuroscience.
2002;22(4):1280-1289. doi:10.1523/JNEUROSCI.22-04-01280.2002
apa: Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y.,
& Nakanishi, S. (2002). Tamalin, a PDZ domain-containing protein, links a
protein complex formation of group 1 metabotropic glutamate receptors and the
guanine nucleotide exchange factor cytohesins. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002
chicago: Kitano, Jun, Kouji Kimura, Yoshimitsu Yamazaki, Takeshi Soda, Ryuichi Shigemoto,
Yoshiaki Nakajima, and Shigetada Nakanishi. “Tamalin, a PDZ Domain-Containing
Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors
and the Guanine Nucleotide Exchange Factor Cytohesins.” Journal of Neuroscience.
Society for Neuroscience, 2002. https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002.
ieee: J. Kitano et al., “Tamalin, a PDZ domain-containing protein, links
a protein complex formation of group 1 metabotropic glutamate receptors and the
guanine nucleotide exchange factor cytohesins,” Journal of Neuroscience,
vol. 22, no. 4. Society for Neuroscience, pp. 1280–1289, 2002.
ista: Kitano J, Kimura K, Yamazaki Y, Soda T, Shigemoto R, Nakajima Y, Nakanishi
S. 2002. Tamalin, a PDZ domain-containing protein, links a protein complex formation
of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange
factor cytohesins. Journal of Neuroscience. 22(4), 1280–1289.
mla: Kitano, Jun, et al. “Tamalin, a PDZ Domain-Containing Protein, Links a Protein
Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine
Nucleotide Exchange Factor Cytohesins.” Journal of Neuroscience, vol. 22,
no. 4, Society for Neuroscience, 2002, pp. 1280–89, doi:10.1523/JNEUROSCI.22-04-01280.2002.
short: J. Kitano, K. Kimura, Y. Yamazaki, T. Soda, R. Shigemoto, Y. Nakajima, S.
Nakanishi, Journal of Neuroscience 22 (2002) 1280–1289.
date_created: 2018-12-11T11:58:40Z
date_published: 2002-02-15T00:00:00Z
date_updated: 2023-07-25T11:34:46Z
day: '15'
doi: 10.1523/JNEUROSCI.22-04-01280.2002
extern: '1'
external_id:
pmid:
- '11850456'
intvolume: ' 22'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 1280 - 1289
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '4285'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tamalin, a PDZ domain-containing protein, links a protein complex formation
of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange
factor cytohesins
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 22
year: '2002'
...
---
_id: '2616'
abstract:
- lang: eng
text: Neurons in the rat cerebral cortex are enriched in group I metabotropic glutamate
receptor (mGluR) subtypes and respond to their activation during development.
To understand better the mechanisms by which mGluR1 and mGluR5 mediate these effects,
the goal of this study was to elucidate the expression pattern and to determine
the cellular and the precise subcellular localization of these two receptor subtypes
in the rat neocortex and hippocampus during late prenatal and postnatal development.
At the light microscopic level, mGluR1 α and mGluR5 were first detected in the
cerebral cortex with different expression levels at embryonic day E18. Thus, mGluR5
had a moderate expression, whereas mGluR1 α was detected as a diffuse and weak
labeling. mGluR5 was localized in some Cajal-Retzius cells as well as in other
cell types, such as pioneer neurons of the marginal zone. During postnatal development,
the distribution of the receptors dramatically changed. From P0 to around P10,
mGluR1α was localized in identified, transient Cajal-Retzius cells of neocortex
and hippocampus, until these cells disappear. In addition, a population of interneurons
localized the receptor from the second/third postnatal week. In contrast, mGluR5
was localized mainly in pyramidal cells and in some interneurons, with a neuropilar
staining throughout the cerebral cortex. At the electron microscopic level, the
immunoreactivity for both group I mGluR subtypes was expressed postsynaptically.
Using immunogold methods, mGluR1α and mGluR5 immunoreactivities were found throughout
postnatal development at the edge of postsynaptic specialization of asymmetrical
synapses. These results show that the two group I mGluRs have a differential expression
pattern in neocortex and hippocampus that may suggest roles for the receptors
in the early processing of cortical information and in the control of cortical
developmental events.
acknowledgement: The authors are grateful to Dr Ole Paulsen and Professor Kay Davies
for their comments on the manuscript. We also would like to thank Dr Zoltan Molnar
for his support and Mrs Lucy Jones, Ms Courtney Voelker and Mr David Dongworth for
the English revision of the manuscript. This work was supported by grants from the
European Community (QLG3-CT-1999-00192 to R.L.) and the Spanish Ministerio de Ciencia
y Tecnología (PB97-0582-CO2-01 to A.F.).
article_processing_charge: No
article_type: original
author:
- first_name: Guillermina
full_name: López Bendito, Guillermina
last_name: López Bendito
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Alfonso
full_name: Fairén, Alfonso
last_name: Fairén
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
citation:
ama: López Bendito G, Shigemoto R, Fairén A, Luján R. Differential distribution
of group I metabotropic glutamate receptors during rat cortical development. Cerebral
Cortex. 2002;12(6):625-638. doi:10.1093/cercor/12.6.625
apa: López Bendito, G., Shigemoto, R., Fairén, A., & Luján, R. (2002). Differential
distribution of group I metabotropic glutamate receptors during rat cortical development.
Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/12.6.625
chicago: López Bendito, Guillermina, Ryuichi Shigemoto, Alfonso Fairén, and Rafael
Luján. “Differential Distribution of Group I Metabotropic Glutamate Receptors
during Rat Cortical Development.” Cerebral Cortex. Oxford University Press,
2002. https://doi.org/10.1093/cercor/12.6.625.
ieee: G. López Bendito, R. Shigemoto, A. Fairén, and R. Luján, “Differential distribution
of group I metabotropic glutamate receptors during rat cortical development,”
Cerebral Cortex, vol. 12, no. 6. Oxford University Press, pp. 625–638,
2002.
ista: López Bendito G, Shigemoto R, Fairén A, Luján R. 2002. Differential distribution
of group I metabotropic glutamate receptors during rat cortical development. Cerebral
Cortex. 12(6), 625–638.
mla: López Bendito, Guillermina, et al. “Differential Distribution of Group I Metabotropic
Glutamate Receptors during Rat Cortical Development.” Cerebral Cortex,
vol. 12, no. 6, Oxford University Press, 2002, pp. 625–38, doi:10.1093/cercor/12.6.625.
short: G. López Bendito, R. Shigemoto, A. Fairén, R. Luján, Cerebral Cortex 12 (2002)
625–638.
date_created: 2018-12-11T11:58:41Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-25T09:54:10Z
day: '01'
doi: 10.1093/cercor/12.6.625
extern: '1'
external_id:
pmid:
- '12003862'
intvolume: ' 12'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 625 - 638
pmid: 1
publication: Cerebral Cortex
publication_identifier:
issn:
- 1047-3211
publication_status: published
publisher: Oxford University Press
publist_id: '4282'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Differential distribution of group I metabotropic glutamate receptors during
rat cortical development
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '2619'
abstract:
- lang: eng
text: The release of glutamate and GABA is modulated by presynaptic metabotropic
glutamate receptors (mGluRs). We used immunocytochemical methods to define the
location of the group III receptor mGluR7a in glutamatergic and GABAergic terminals
innervating GABAergic interneurons and pyramidal cells. Immunoreactivity for mGluR7a
was localized in the presynaptic active zone of both identified GABAergic and
presumed glutamatergic terminals. Terminals innervating dendritic spines showed
a variable level of receptor immunoreactivity, ranging from immunonegative to
strongly immunopositive. The frequency of strongly mGluR7a positive terminals
innervating the soma and dendrites of mGluR1α/somatostatin-expressing interneurons
was very high relative to other neurons. On dendrites that received mGluR7a-enriched
glutamatergic innervation, at least 80% of GABAergic terminals were immunopositive
for mGluR7a. On such dendrites virtually all (95%) vasoactive intestinal polypeptide
(VIP) positive (GABAergic) terminals were enriched in mGluR7a. The targets of
VIP/mGluR7a-expressing terminals were mainly (88%) mGluR1α-expressing interneurons,
which were mostly somatostatin immunopositive. Parvalbumin positive terminals
were immunonegative for mGluR7a. Some parvalbumin immunoreactive dendrites received
strongly mGluR7a positive terminals. The subcellular location, as well as the
cell type and synapse-specific distribution of mGluR7a in isocortical neuronal
circuits, is homologous to its distribution in the hippocampus. The specific location
of mGluR7a in the presynaptic active zone of both glutamatergic and GABAergic
synapses may be related to the proximity of calcium channels and the vesicle fusion
machinery. The enrichment of mGluR7a in the main GABAergic, as well as in the
glutamatergic, innervation of mGluR1α/somatostatin-expressing interneurons suggests
that their activation is under unique regulation by extracellular glutamate.
acknowledgement: We thank Dr C. Paspalas for an initial contribution to the immunocytochemistry.
We are grateful for the generous gifts of antibodies from Dr A. Buchan (anti-somatostatin,
Department of Physiology, University of British Columbia, Canada), Dr M. Watanabe
(anti-mGluR1α, Department of Anatomy, Hokkaido University School of Medicine, Sapporo)
and Dr K. Tanaka (anti-GAD, Niigata University, Faculty of Medicine, Department
of Neurology). We thank Dr F. Ferraguti for helpful suggestions during the project
and for his comments on a previous version of the manuscript. We also thank Philip
Cobden, Paul Jays and Laszlo Marton for assistance. Y.D. was supported by a Wellcome
Trust Advanced Training Fellowship.
article_processing_charge: No
article_type: original
author:
- first_name: Yannis
full_name: Dalezios, Yannis
last_name: Dalezios
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: John
full_name: Roberts, John
last_name: Roberts
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Dalezios Y, Luján R, Shigemoto R, Roberts J, Somogyi P. Enrichment of mGluR7a
in the Presynaptic active zones of GABAergic and Non-GABAergic terminals on interneurons
in the rat somatosensory cortex. Cerebral Cortex. 2002;12(9):961-974. doi:10.1093/cercor/12.9.961
apa: Dalezios, Y., Luján, R., Shigemoto, R., Roberts, J., & Somogyi, P. (2002).
Enrichment of mGluR7a in the Presynaptic active zones of GABAergic and Non-GABAergic
terminals on interneurons in the rat somatosensory cortex. Cerebral Cortex.
Oxford University Press. https://doi.org/10.1093/cercor/12.9.961
chicago: Dalezios, Yannis, Rafael Luján, Ryuichi Shigemoto, John Roberts, and Péter
Somogyi. “Enrichment of MGluR7a in the Presynaptic Active Zones of GABAergic and
Non-GABAergic Terminals on Interneurons in the Rat Somatosensory Cortex.” Cerebral
Cortex. Oxford University Press, 2002. https://doi.org/10.1093/cercor/12.9.961.
ieee: Y. Dalezios, R. Luján, R. Shigemoto, J. Roberts, and P. Somogyi, “Enrichment
of mGluR7a in the Presynaptic active zones of GABAergic and Non-GABAergic terminals
on interneurons in the rat somatosensory cortex,” Cerebral Cortex, vol.
12, no. 9. Oxford University Press, pp. 961–974, 2002.
ista: Dalezios Y, Luján R, Shigemoto R, Roberts J, Somogyi P. 2002. Enrichment of
mGluR7a in the Presynaptic active zones of GABAergic and Non-GABAergic terminals
on interneurons in the rat somatosensory cortex. Cerebral Cortex. 12(9), 961–974.
mla: Dalezios, Yannis, et al. “Enrichment of MGluR7a in the Presynaptic Active Zones
of GABAergic and Non-GABAergic Terminals on Interneurons in the Rat Somatosensory
Cortex.” Cerebral Cortex, vol. 12, no. 9, Oxford University Press, 2002,
pp. 961–74, doi:10.1093/cercor/12.9.961.
short: Y. Dalezios, R. Luján, R. Shigemoto, J. Roberts, P. Somogyi, Cerebral Cortex
12 (2002) 961–974.
date_created: 2018-12-11T11:58:42Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-07-25T09:40:49Z
day: '01'
doi: 10.1093/cercor/12.9.961
extern: '1'
external_id:
pmid:
- '12183395'
intvolume: ' 12'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 961 - 974
pmid: 1
publication: Cerebral Cortex
publication_identifier:
issn:
- 1047-3211
publication_status: published
publisher: Oxford University Press
publist_id: '4280'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Enrichment of mGluR7a in the Presynaptic active zones of GABAergic and Non-GABAergic
terminals on interneurons in the rat somatosensory cortex
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '2615'
abstract:
- lang: eng
text: Taste-mGluR4, cloned from taste tissues, is a truncated variant of brain-expressed
mGluR4a (brain-mGluR4), and is known to be a candidate for the receptor involved
in the umami taste sense. Although the expression patterns of taste- and brain-mGluR4
mRNAs have been demonstrated, no mention has so far been made of the expression
of these two mGluR4 proteins in taste tissues. The present study examined the
expression of taste-mGluR4 and brain-mGluR4 proteins in rat taste tissues by using
a specific antibody for mGluR4a which shared a C-terminus of both taste- and brain-mGluR4,
for immunoblot analysis and immunohistochemistry. Immunoblot analysis showed that
both brain-mGluR4 and taste-mGluR4 were expressed in the taste tissues. Taste-mGluR4
was not detected in the cerebellum. The immunoreactive band for brain-mGluR4 protein
was much stronger than that for taste-mGluR4 protein. In the cryosections of fungiform,
foliate and circumvallate papillae, the antibody against taste-mGluR4 exhibited
intense labeling of the taste pores and taste hairs in all the taste buds of gustatory
papillae examined; the immunoreaction to the antibody against brain-mGluR4 was
more intense at the same sites of the taste buds. The portions of the taste bud
cells below the taste pore and surrounding keratinocytes did not show any immunoreactivities.
The results of the present study strongly suggest that, in addition to taste-mGluR4,
brain-mGluR4 may function even more importantly than the former as a receptor
for glutamate, i.e. the umami taste sensation.
article_processing_charge: No
article_type: original
author:
- first_name: Takashi
full_name: Toyono, Takashi
last_name: Toyono
- first_name: Yuji
full_name: Seta, Yuji
last_name: Seta
- first_name: Shinji
full_name: Sataoka, Shinji
last_name: Sataoka
- first_name: Harumi
full_name: Harada, Harumi
id: 2E55CDF2-F248-11E8-B48F-1D18A9856A87
last_name: Harada
orcid: 0000-0001-7429-7896
- first_name: Takahiko
full_name: Morotomi, Takahiko
last_name: Morotomi
- first_name: Shintaro
full_name: Kawano, Shintaro
last_name: Kawano
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kuniaki
full_name: Toyoshima, Kuniaki
last_name: Toyoshima
citation:
ama: Toyono T, Seta Y, Sataoka S, et al. Expression of the metabotropic glutamate
receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae.
Archives of Histology and Cytology. 2002;65(1):91-96. doi:10.1679/aohc.65.91
apa: Toyono, T., Seta, Y., Sataoka, S., Harada, H., Morotomi, T., Kawano, S., …
Toyoshima, K. (2002). Expression of the metabotropic glutamate receptor, mGluR4a,
in the taste hairs of taste buds in rat gustatory papillae. Archives of Histology
and Cytology. Japan Society of Histological Documentation. https://doi.org/10.1679/aohc.65.91
chicago: Toyono, Takashi, Yuji Seta, Shinji Sataoka, Harumi Harada, Takahiko Morotomi,
Shintaro Kawano, Ryuichi Shigemoto, and Kuniaki Toyoshima. “Expression of the
Metabotropic Glutamate Receptor, MGluR4a, in the Taste Hairs of Taste Buds in
Rat Gustatory Papillae.” Archives of Histology and Cytology. Japan Society
of Histological Documentation, 2002. https://doi.org/10.1679/aohc.65.91.
ieee: T. Toyono et al., “Expression of the metabotropic glutamate receptor,
mGluR4a, in the taste hairs of taste buds in rat gustatory papillae,” Archives
of Histology and Cytology, vol. 65, no. 1. Japan Society of Histological Documentation,
pp. 91–96, 2002.
ista: Toyono T, Seta Y, Sataoka S, Harada H, Morotomi T, Kawano S, Shigemoto R,
Toyoshima K. 2002. Expression of the metabotropic glutamate receptor, mGluR4a,
in the taste hairs of taste buds in rat gustatory papillae. Archives of Histology
and Cytology. 65(1), 91–96.
mla: Toyono, Takashi, et al. “Expression of the Metabotropic Glutamate Receptor,
MGluR4a, in the Taste Hairs of Taste Buds in Rat Gustatory Papillae.” Archives
of Histology and Cytology, vol. 65, no. 1, Japan Society of Histological Documentation,
2002, pp. 91–96, doi:10.1679/aohc.65.91.
short: T. Toyono, Y. Seta, S. Sataoka, H. Harada, T. Morotomi, S. Kawano, R. Shigemoto,
K. Toyoshima, Archives of Histology and Cytology 65 (2002) 91–96.
date_created: 2018-12-11T11:58:41Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-25T10:00:15Z
day: '01'
doi: 10.1679/aohc.65.91
extern: '1'
external_id:
pmid:
- '12002614'
intvolume: ' 65'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 91 - 96
pmid: 1
publication: Archives of Histology and Cytology
publication_identifier:
issn:
- 0914-9465
publication_status: published
publisher: Japan Society of Histological Documentation
publist_id: '4283'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs
of taste buds in rat gustatory papillae
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 65
year: '2002'
...
---
_id: '2618'
abstract:
- lang: eng
text: The unipolar brush cell (UBC) is a type of glutamatergic interneuron in the
granular layer of the cerebellum. The UBC brush and a single mossy fiber (MF)
terminal contact each other within a cerebellar glomerulus, forming a giant synapse.
Many UBCs receive input from extrinsic MFs, whereas others are innervated by intrinsic
mossy terminals formed by the axons of other UBCs. In all mammalian species so
far examined, the vestibulocerebellum is enriched of UBCs that are strongly immunoreactive
for the calcium binding protein calretinin (CR) in both the somatodendritic and
axonal compartment. UBCs have postsynaptic ionotropic glutamate receptors and
extrasynaptic metabotropic glutamate receptors that immunocytochemically highlight
their somatodendritic compartment and brush, respectively. In this study on the
mouse cerebellum, we present evidence that immunoreactivities to CR and mGluR1α
define two distinct UBC subsets with partly overlapping distributions in lobule
X (the nodulus). In sections double-labeled for CR and mGluR1α, the patterns of
distributions of CR+/mGluR1α- UBCs and CR-/mGluR1α+ UBCs differed along the mediolateral
and dorsoventral axes of the folium. Moreover, mGluR1α+ UBCs outnumbered CR+ UBCs.
Both UBC subsets were mGluR2/3, GluR2/3, and NMDAR1 immunoreactive. The different
distribution patterns of the two UBC subsets within lobule X suggest that expression
of CR or mGluR1α by UBCs may be afferent-specific and related to the terminal
fields of different vestibular MF afferents.
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Nunzi, Maria
last_name: Nunzi
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Enrico
full_name: Mugnaini, Enrico
last_name: Mugnaini
citation:
ama: Nunzi M, Shigemoto R, Mugnaini E. Differential expression of calretinin and
metabotropic glutamate receptor mGluR1α defines subsets of unipolar brush cells
in mouse cerebellum. Journal of Comparative Neurology. 2002;451(2):189-199.
doi:10.1002/cne.10344
apa: Nunzi, M., Shigemoto, R., & Mugnaini, E. (2002). Differential expression
of calretinin and metabotropic glutamate receptor mGluR1α defines subsets of unipolar
brush cells in mouse cerebellum. Journal of Comparative Neurology. Wiley-Blackwell.
https://doi.org/10.1002/cne.10344
chicago: Nunzi, Maria, Ryuichi Shigemoto, and Enrico Mugnaini. “Differential Expression
of Calretinin and Metabotropic Glutamate Receptor MGluR1α Defines Subsets of Unipolar
Brush Cells in Mouse Cerebellum.” Journal of Comparative Neurology. Wiley-Blackwell,
2002. https://doi.org/10.1002/cne.10344.
ieee: M. Nunzi, R. Shigemoto, and E. Mugnaini, “Differential expression of calretinin
and metabotropic glutamate receptor mGluR1α defines subsets of unipolar brush
cells in mouse cerebellum,” Journal of Comparative Neurology, vol. 451,
no. 2. Wiley-Blackwell, pp. 189–199, 2002.
ista: Nunzi M, Shigemoto R, Mugnaini E. 2002. Differential expression of calretinin
and metabotropic glutamate receptor mGluR1α defines subsets of unipolar brush
cells in mouse cerebellum. Journal of Comparative Neurology. 451(2), 189–199.
mla: Nunzi, Maria, et al. “Differential Expression of Calretinin and Metabotropic
Glutamate Receptor MGluR1α Defines Subsets of Unipolar Brush Cells in Mouse Cerebellum.”
Journal of Comparative Neurology, vol. 451, no. 2, Wiley-Blackwell, 2002,
pp. 189–99, doi:10.1002/cne.10344.
short: M. Nunzi, R. Shigemoto, E. Mugnaini, Journal of Comparative Neurology 451
(2002) 189–199.
date_created: 2018-12-11T11:58:42Z
date_published: 2002-09-16T00:00:00Z
date_updated: 2023-07-25T09:09:48Z
day: '16'
doi: 10.1002/cne.10344
extern: '1'
external_id:
pmid:
- '12209836'
intvolume: ' 451'
issue: '2'
language:
- iso: eng
month: '09'
oa_version: None
page: 189 - 199
pmid: 1
publication: Journal of Comparative Neurology
publication_identifier:
issn:
- 0021-9967
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4279'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Differential expression of calretinin and metabotropic glutamate receptor mGluR1α
defines subsets of unipolar brush cells in mouse cerebellum
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 451
year: '2002'
...
---
_id: '2421'
abstract:
- lang: eng
text: Intersection graphs of disks and of line segments, respectively, have been
well studied, because of both, practical applications and theoretically interesting
properties of these graphs. Despite partial results, the complexity status of
the Clique problem for these two graph classes is still open. Here, we consider
the Clique problem for intersection graphs of ellipses which in a sense, interpolate
between disc and ellipses, and show that it is APX-hard in that case. Moreover,
this holds even if for all ellipses, the ratio of the larger over the smaller
radius is some prescribed number. To our knowledge, this is the first hardness
result for the Clique problem in intersection graphs of objects with finite description
complexity. We also describe a simple approximation algorithm for the case of
ellipses for which the ratio of radii is bounded.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Christoph
full_name: Ambühl, Christoph
last_name: Ambühl
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Ambühl C, Wagner U. On the Clique problem in intersection graphs of ellipses.
In: Proceedings of the 13th International Symposium on Algorithms and Computation.
Vol 2518. Springer; 2002:489-500. doi:10.1007/3-540-36136-7_43'
apa: 'Ambühl, C., & Wagner, U. (2002). On the Clique problem in intersection
graphs of ellipses. In Proceedings of the 13th International Symposium on Algorithms
and Computation (Vol. 2518, pp. 489–500). Vancouver, Canada: Springer. https://doi.org/10.1007/3-540-36136-7_43'
chicago: Ambühl, Christoph, and Uli Wagner. “On the Clique Problem in Intersection
Graphs of Ellipses.” In Proceedings of the 13th International Symposium on
Algorithms and Computation, 2518:489–500. Springer, 2002. https://doi.org/10.1007/3-540-36136-7_43.
ieee: C. Ambühl and U. Wagner, “On the Clique problem in intersection graphs of
ellipses,” in Proceedings of the 13th International Symposium on Algorithms
and Computation, Vancouver, Canada, 2002, vol. 2518, pp. 489–500.
ista: 'Ambühl C, Wagner U. 2002. On the Clique problem in intersection graphs of
ellipses. Proceedings of the 13th International Symposium on Algorithms and Computation.
ISAAC: International Symposium on Algorithms and Computation, LNCS, vol. 2518,
489–500.'
mla: Ambühl, Christoph, and Uli Wagner. “On the Clique Problem in Intersection Graphs
of Ellipses.” Proceedings of the 13th International Symposium on Algorithms
and Computation, vol. 2518, Springer, 2002, pp. 489–500, doi:10.1007/3-540-36136-7_43.
short: C. Ambühl, U. Wagner, in:, Proceedings of the 13th International Symposium
on Algorithms and Computation, Springer, 2002, pp. 489–500.
conference:
end_date: 2002-11-23
location: Vancouver, Canada
name: 'ISAAC: International Symposium on Algorithms and Computation'
start_date: 2002-11-21
date_created: 2018-12-11T11:57:34Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-25T11:48:36Z
day: '01'
doi: 10.1007/3-540-36136-7_43
extern: '1'
intvolume: ' 2518'
language:
- iso: eng
month: '01'
oa_version: None
page: 489 - 500
publication: Proceedings of the 13th International Symposium on Algorithms and Computation
publication_identifier:
isbn:
- '9783540001423'
publication_status: published
publisher: Springer
publist_id: '4504'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the Clique problem in intersection graphs of ellipses
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2518
year: '2002'
...
---
_id: '2353'
abstract:
- lang: eng
text: A commonly used theoretical definition of superfluidity in the ground state
of a Bose gas is based on the response of the system to an imposed velocity field
or, equivalently, to twisted boundary conditions in a box. We are able to carry
out this program in the case of a dilute interacting Bose gas in a trap, and we
prove that a gas with repulsive interactions is 100% superfluid in the dilute
limit in which the Gross-Pitaevskii equation is exact. This is the first example
in an experimentally realistic continuum model in which superfluidity is rigorously
verified.
acknowledgement: E.H.L. was partially supported by the U.S. National Science Foundation,
Grant No. PHY 98-20650. R.S. was supported by the Austrian Science Fund in the from
of an Erwin Schrödinger fellowship.
article_processing_charge: No
article_type: original
author:
- first_name: Élliott
full_name: Lieb, Élliott
last_name: Lieb
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: Lieb É, Seiringer R, Yngvason J. Superfluidity in dilute trapped Bose gases.
Physical Review B - Condensed Matter and Materials Physics. 2002;66(13).
doi:10.1103/PhysRevB.66.134529
apa: Lieb, É., Seiringer, R., & Yngvason, J. (2002). Superfluidity in dilute
trapped Bose gases. Physical Review B - Condensed Matter and Materials Physics.
American Physical Society. https://doi.org/10.1103/PhysRevB.66.134529
chicago: Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “Superfluidity in
Dilute Trapped Bose Gases.” Physical Review B - Condensed Matter and Materials
Physics. American Physical Society, 2002. https://doi.org/10.1103/PhysRevB.66.134529.
ieee: É. Lieb, R. Seiringer, and J. Yngvason, “Superfluidity in dilute trapped Bose
gases,” Physical Review B - Condensed Matter and Materials Physics, vol.
66, no. 13. American Physical Society, 2002.
ista: Lieb É, Seiringer R, Yngvason J. 2002. Superfluidity in dilute trapped Bose
gases. Physical Review B - Condensed Matter and Materials Physics. 66(13).
mla: Lieb, Élliott, et al. “Superfluidity in Dilute Trapped Bose Gases.” Physical
Review B - Condensed Matter and Materials Physics, vol. 66, no. 13, American
Physical Society, 2002, doi:10.1103/PhysRevB.66.134529.
short: É. Lieb, R. Seiringer, J. Yngvason, Physical Review B - Condensed Matter
and Materials Physics 66 (2002).
date_created: 2018-12-11T11:57:10Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-07-25T12:05:47Z
day: '01'
doi: 10.1103/PhysRevB.66.134529
extern: '1'
external_id:
arxiv:
- cond-mat/0205570
intvolume: ' 66'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/cond-mat/0205570
month: '10'
oa: 1
oa_version: None
publication: Physical Review B - Condensed Matter and Materials Physics
publication_identifier:
issn:
- 0163-1829
publication_status: published
publisher: American Physical Society
publist_id: '4573'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Superfluidity in dilute trapped Bose gases
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 66
year: '2002'
...
---
_id: '2420'
abstract:
- lang: eng
text: 'A corner cut in dimension d is a finite subset of N0d that can be separated
from its complement in N0d by an affine hyperplane disjoint from N0d. Corner cuts
were first investigated by Onn and Sturmfels [Adv. Appl. Math. 23 (1999) 29-48],
their original motivation stemmed from computational commutative algebra. Let
us write (Nd0k)cut for the set of corner cuts of cardinality k; in the computational
geometer''s terminology, these are the k-sets of N0d. Among other things, Onn
and Sturmfels give an upper bound of O(k2d(d-1)/(d+1)) for the size of (Nd0k)cut
when the dimension is fixed. In two dimensions, it is known (see [Corteel et al.,
Adv. Appl. Math. 23 (1) (1999) 49-53]) that #(Nd0k)cut = Θ(k log k). We will see
that in general, for any fixed dimension d, the order of magnitude of #(Nd0k)cut
is between kd-1 log k and (k log k)d-1. (It has been communicated to me that the
same bounds have been found independently by G. Rémond.) In fact, the elements
of (Nd0k)cut correspond to the vertices of a certain polytope, and what our proof
shows is that the above upper bound holds for the total number of flags of that
polytope.'
acknowledgement: "I first learned about corner cuts in a seminar talk in which Artur
Andrzejak\r\npresented the results from [6]. My work was initiated by that presentation
and\r\nby the discussions that followed it. I also thank Komei Fukuda, Ingo Schurr,
and\r\nEmo Welzl for helpful comments and discussions."
article_processing_charge: No
article_type: original
author:
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Wagner U. On the number of corner cuts. Advances in Applied Mathematics.
2002;29(2):152-161. doi:10.1016/S0196-8858(02)00014-3
apa: Wagner, U. (2002). On the number of corner cuts. Advances in Applied Mathematics.
ACM. https://doi.org/10.1016/S0196-8858(02)00014-3
chicago: Wagner, Uli. “On the Number of Corner Cuts.” Advances in Applied Mathematics.
ACM, 2002. https://doi.org/10.1016/S0196-8858(02)00014-3.
ieee: U. Wagner, “On the number of corner cuts,” Advances in Applied Mathematics,
vol. 29, no. 2. ACM, pp. 152–161, 2002.
ista: Wagner U. 2002. On the number of corner cuts. Advances in Applied Mathematics.
29(2), 152–161.
mla: Wagner, Uli. “On the Number of Corner Cuts.” Advances in Applied Mathematics,
vol. 29, no. 2, ACM, 2002, pp. 152–61, doi:10.1016/S0196-8858(02)00014-3.
short: U. Wagner, Advances in Applied Mathematics 29 (2002) 152–161.
date_created: 2018-12-11T11:57:33Z
date_published: 2002-08-01T00:00:00Z
date_updated: 2023-07-25T11:55:42Z
day: '01'
doi: 10.1016/S0196-8858(02)00014-3
extern: '1'
intvolume: ' 29'
issue: '2'
language:
- iso: eng
month: '08'
oa_version: None
page: 152 - 161
publication: Advances in Applied Mathematics
publication_identifier:
issn:
- 0196-8858
publication_status: published
publisher: ACM
publist_id: '4505'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the number of corner cuts
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 29
year: '2002'
...
---
_id: '2338'
abstract:
- lang: eng
text: Now that the low temperature properties of quantum-mechanical many-body systems
(bosons) at low density, ρ, can be examined experimentally it is appropriate to
revisit some of the formulas deduced by many authors 4-5 decades ago. For systems
with repulsive (i.e. positive) interaction potentials the experimental low temperature
state and the ground state are effectively synonymous -- and this fact is used
in all modeling. In such cases, the leading term in the energy/particle is 2πℏ2aρ/m
where a is the scattering length of the two-body potential. Owing to the delicate
and peculiar nature of bosonic correlations (such as the strange N7/5 law for
charged bosons), four decades of research failed to establish this plausible formula
rigorously. The only previous lower bound for the energy was found by Dyson in
1957, but it was 14 times too small. The correct asymptotic formula has recently
been obtained by us and this work will be presented. The reason behind the mathematical
difficulties will be emphasized. A different formula, postulated as late as 1971
by Schick, holds in two-dimensions and this, too, will be shown to be correct.
With the aid of the methodology developed to prove the lower bound for the homogeneous
gas, two other problems have been successfully addressed. One is the proof by
us that the Gross-Pitaevskii equation correctly describes the ground state in
the `traps' actually used in the experiments. For this system it is also possible
to prove complete Bose condensation, as we have shown. Another topic is a proof
that Foldy's 1961 theory of a high density Bose gas of charged particles correctly
describes its ground state energy.
alternative_title:
- Current Developments in Mathematics
article_processing_charge: No
author:
- first_name: Élliott
full_name: Lieb, Élliott
last_name: Lieb
- first_name: Jan
full_name: Solovej, Jan
last_name: Solovej
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: 'Lieb É, Solovej J, Seiringer R, Yngvason J. The ground state of the Bose gas.
In: Current Developments in Mathematics, 2001. International Press; 2002:131-178.
doi:10.48550/arXiv.math-ph/0204027'
apa: Lieb, É., Solovej, J., Seiringer, R., & Yngvason, J. (2002). The ground
state of the Bose gas. In Current Developments in Mathematics, 2001 (pp.
131–178). International Press. https://doi.org/10.48550/arXiv.math-ph/0204027
chicago: Lieb, Élliott, Jan Solovej, Robert Seiringer, and Jakob Yngvason. “The
Ground State of the Bose Gas.” In Current Developments in Mathematics, 2001,
131–78. International Press, 2002. https://doi.org/10.48550/arXiv.math-ph/0204027.
ieee: É. Lieb, J. Solovej, R. Seiringer, and J. Yngvason, “The ground state of the
Bose gas,” in Current Developments in Mathematics, 2001, International
Press, 2002, pp. 131–178.
ista: 'Lieb É, Solovej J, Seiringer R, Yngvason J. 2002.The ground state of the
Bose gas. In: Current Developments in Mathematics, 2001. Current Developments
in Mathematics, , 131–178.'
mla: Lieb, Élliott, et al. “The Ground State of the Bose Gas.” Current Developments
in Mathematics, 2001, International Press, 2002, pp. 131–78, doi:10.48550/arXiv.math-ph/0204027.
short: É. Lieb, J. Solovej, R. Seiringer, J. Yngvason, in:, Current Developments
in Mathematics, 2001, International Press, 2002, pp. 131–178.
date_created: 2018-12-11T11:57:04Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-26T08:43:46Z
day: '01'
doi: 10.48550/arXiv.math-ph/0204027
extern: '1'
external_id:
arxiv:
- math-ph/0204027
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0204027
month: '01'
oa: 1
oa_version: Published Version
page: 131 - 178
publication: Current Developments in Mathematics, 2001
publication_identifier:
isbn:
- '9781571461018'
publication_status: published
publisher: International Press
publist_id: '4588'
status: public
title: The ground state of the Bose gas
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '1737'
abstract:
- lang: eng
text: A new solvent-free composite polymer electrolyte consisting of high-molecular
mass polyethylene oxide (PEO) filled with titanium oxide and containing LiI and
I2 was developed. The introduction of the inorganic filler (TiO2 Degussa P25)
into the polymer matrix produces dramatic morphological changes to the host polymer
structure. Upon addition of the inorganic oxide, the surface roughness increases,
with respect to the original polymer and in parallel, the fractal dimension decreases.
Both the thermograms and the atomic force microscope (AFM) pictures confirm the
amorphicity of the composite electrolyte. The polymer sub-units are held together
in a parallel orientation, forming straight long chains of about 500 nm in width,
along which TiO2 spherical particles of about 20-25 nm in diameter are distributed.
The polymer chains separated by the titania particles are arranged in a three-dimensional,
mechanically stable network, that creates free space and voids into which the
iodide/triodide anions can easily migrate. All solid-state dye-sensitized solar
cells fabricated using this composite electrolyte present high efficiencies (typical
maximum incident photon to current efficiency (IPCE) as high as 40% at 520 nm
and overall conversion efficiency (η) of 0.96% (Voc = 0.67 V, Jsc = 2.050 mA/cm2,
FF = 39%) under direct solar irradiation. Further improvement of the photovoltaic
performance is expected by optimization of the electrolyte parameters and of the
cell assembly.
acknowledgement: Financial support from NCSR “Demokritos” (Dimoerevna 598 project),
Empeirikeion Foundation and General Secretariat for Research and Technology of Greece
(EPET II, Greece–France and Greece–Czech Republic bilateral collaboration projects)
is also greatly acknowledged. G. Katsaros thanks the Greek State Scholarships Foundation
(IKY) for fellowship allowance
article_processing_charge: No
author:
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Thomas
full_name: Stergiopoulos, Thomas
last_name: Stergiopoulos
- first_name: Iannis
full_name: Arabatzis, Iannis
last_name: Arabatzis
- first_name: Kyriaki
full_name: Papadokostaki, Kyriaki
last_name: Papadokostaki
- first_name: Polycarpos
full_name: Falaras, Polycarpos
last_name: Falaras
citation:
ama: 'Katsaros G, Stergiopoulos T, Arabatzis I, Papadokostaki K, Falaras P. A solvent-free
composite polymer/inorganic oxide electrolyte for high efficiency solid-state
dye-sensitized solar cells. Journal of Photochemistry and Photobiology A: Chemistry.
2002;149(1-3):191-198. doi:10.1016/S1010-6030(02)00027-8'
apa: 'Katsaros, G., Stergiopoulos, T., Arabatzis, I., Papadokostaki, K., & Falaras,
P. (2002). A solvent-free composite polymer/inorganic oxide electrolyte for high
efficiency solid-state dye-sensitized solar cells. Journal of Photochemistry
and Photobiology A: Chemistry. Elsevier. https://doi.org/10.1016/S1010-6030(02)00027-8'
chicago: 'Katsaros, Georgios, Thomas Stergiopoulos, Iannis Arabatzis, Kyriaki Papadokostaki,
and Polycarpos Falaras. “A Solvent-Free Composite Polymer/Inorganic Oxide Electrolyte
for High Efficiency Solid-State Dye-Sensitized Solar Cells.” Journal of Photochemistry
and Photobiology A: Chemistry. Elsevier, 2002. https://doi.org/10.1016/S1010-6030(02)00027-8.'
ieee: 'G. Katsaros, T. Stergiopoulos, I. Arabatzis, K. Papadokostaki, and P. Falaras,
“A solvent-free composite polymer/inorganic oxide electrolyte for high efficiency
solid-state dye-sensitized solar cells,” Journal of Photochemistry and Photobiology
A: Chemistry, vol. 149, no. 1–3. Elsevier, pp. 191–198, 2002.'
ista: 'Katsaros G, Stergiopoulos T, Arabatzis I, Papadokostaki K, Falaras P. 2002.
A solvent-free composite polymer/inorganic oxide electrolyte for high efficiency
solid-state dye-sensitized solar cells. Journal of Photochemistry and Photobiology
A: Chemistry. 149(1–3), 191–198.'
mla: 'Katsaros, Georgios, et al. “A Solvent-Free Composite Polymer/Inorganic Oxide
Electrolyte for High Efficiency Solid-State Dye-Sensitized Solar Cells.” Journal
of Photochemistry and Photobiology A: Chemistry, vol. 149, no. 1–3, Elsevier,
2002, pp. 191–98, doi:10.1016/S1010-6030(02)00027-8.'
short: 'G. Katsaros, T. Stergiopoulos, I. Arabatzis, K. Papadokostaki, P. Falaras,
Journal of Photochemistry and Photobiology A: Chemistry 149 (2002) 191–198.'
date_created: 2018-12-11T11:53:44Z
date_published: 2002-06-28T00:00:00Z
date_updated: 2023-07-26T08:56:55Z
day: '28'
doi: 10.1016/S1010-6030(02)00027-8
extern: '1'
intvolume: ' 149'
issue: 1-3
language:
- iso: eng
month: '06'
oa_version: None
page: 191 - 198
publication: 'Journal of Photochemistry and Photobiology A: Chemistry'
publication_identifier:
issn:
- 1010-6030
publication_status: published
publisher: Elsevier
publist_id: '5387'
status: public
title: A solvent-free composite polymer/inorganic oxide electrolyte for high efficiency
solid-state dye-sensitized solar cells
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 149
year: '2002'
...
---
_id: '2350'
abstract:
- lang: eng
text: Using the Pauli-Fierz model of non-relativistic quantum electrodynamics, we
calculate the binding energy of an electron in the field of a nucleus of charge
Z and in presence of the quantized radiation field. We consider the case of small
coupling constant α, but fixed Zα and ultraviolet cut-off Λ. We prove that after
renormalizing the mass the binding energy has, to leading order in α, a finite
limit as Λ goes to infinity; i.e., the cut-off can be removed. The expression
for the ground state energy shift thus obtained agrees with Bethe's formula for
small values of Zα, but shows a different behavior for bigger values.
acknowledgement: "We are grateful to Elliott Lieb for helpful discussions. C.H. was
supported by a Marie Curie Fellowship of the European Community programme “Improving
Human Research Potential and the Socioeconomic Knowledge Base” under contract number
HPMFCT-2000-00660 and by the Deutsche Forschungsgemeinschaft, and acknowledges kind
hospitality at Princeton University, where part of this work was done. R.S. was
supported by the Austrian Science Fund in the form of an Erwin Schrödinger Fellowship.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Hainzl C, Seiringer R. Mass renormalization and energy level shift in non-relativistic
QED. Advances in Theoretical and Mathematical Physics. 2002;6(5):847-871.
doi:10.4310/ATMP.2002.v6.n5.a3
apa: Hainzl, C., & Seiringer, R. (2002). Mass renormalization and energy level
shift in non-relativistic QED. Advances in Theoretical and Mathematical Physics.
International Press. https://doi.org/10.4310/ATMP.2002.v6.n5.a3
chicago: Hainzl, Christian, and Robert Seiringer. “Mass Renormalization and Energy
Level Shift in Non-Relativistic QED.” Advances in Theoretical and Mathematical
Physics. International Press, 2002. https://doi.org/10.4310/ATMP.2002.v6.n5.a3.
ieee: C. Hainzl and R. Seiringer, “Mass renormalization and energy level shift in
non-relativistic QED,” Advances in Theoretical and Mathematical Physics,
vol. 6, no. 5. International Press, pp. 847–871, 2002.
ista: Hainzl C, Seiringer R. 2002. Mass renormalization and energy level shift in
non-relativistic QED. Advances in Theoretical and Mathematical Physics. 6(5),
847–871.
mla: Hainzl, Christian, and Robert Seiringer. “Mass Renormalization and Energy Level
Shift in Non-Relativistic QED.” Advances in Theoretical and Mathematical Physics,
vol. 6, no. 5, International Press, 2002, pp. 847–71, doi:10.4310/ATMP.2002.v6.n5.a3.
short: C. Hainzl, R. Seiringer, Advances in Theoretical and Mathematical Physics
6 (2002) 847–871.
date_created: 2018-12-11T11:57:09Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-07-26T08:29:28Z
day: '01'
doi: 10.4310/ATMP.2002.v6.n5.a3
extern: '1'
external_id:
arxiv:
- math-ph/0205044v3
intvolume: ' 6'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0205044
month: '09'
oa: 1
oa_version: Published Version
page: 847 - 871
publication: Advances in Theoretical and Mathematical Physics
publication_identifier:
issn:
- 1095-0761
publication_status: published
publisher: International Press
publist_id: '4574'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mass renormalization and energy level shift in non-relativistic QED
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 6
year: '2002'
...
---
_id: '885'
abstract:
- lang: eng
text: We study fitness landscape in the space of protein sequences by relating sets
of human pathogenic missense mutations in 32 proteins to amino acid substitutions
that occurred in the course of evolution of these proteins. On average, ≈10% of
deviations of a nonhuman protein from its human ortholog are compensated pathogenic
deviations (CPDs), i.e., are caused by an amino acid substitution that, at this
site, would be pathogenic to humans. Normal functioning of a CPD-containing protein
must be caused by other, compensatory deviations of the nonhuman species from
humans. Together, a CPD and the corresponding compensatory deviation form a Dobzhansky-Muller
incompatibility that can be visualized as the corner on a fitness ridge. Thus,
proteins evolve along fitness ridges which contain only ≈10 steps between sucessive
corners. The fraction of CPDs among all deviations of a protein from its human
ortholog does not increase with the evolutionary distance between the proteins,
indicating that subtitutions that carry evolving proteins around these corners
occur in rapid succession, driven by positive selection. Data on fitness of interspecies
hybrids suggest that the compensatory change that makes a CPD fit usually occurs
within the same protein. Data on protein structures and on cooccurrence of amino
acids at different sites of multiple orthologous proteins often make it possible
to provisionally identify the substitution that compensates a partiCUlar CPD.
article_processing_charge: No
article_type: original
author:
- first_name: Alexey
full_name: Kondrashov, Alexey
last_name: Kondrashov
- first_name: Shamil
full_name: Sunyaev, Shamil
last_name: Sunyaev
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Kondrashov A, Sunyaev S, Kondrashov F. Dobzhansky-Muller incompatibilities
in protein evolution. PNAS. 2002;99(23):14878-14883. doi:10.1073/pnas.232565499
apa: Kondrashov, A., Sunyaev, S., & Kondrashov, F. (2002). Dobzhansky-Muller
incompatibilities in protein evolution. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.232565499
chicago: Kondrashov, Alexey, Shamil Sunyaev, and Fyodor Kondrashov. “Dobzhansky-Muller
Incompatibilities in Protein Evolution.” PNAS. National Academy of Sciences,
2002. https://doi.org/10.1073/pnas.232565499.
ieee: A. Kondrashov, S. Sunyaev, and F. Kondrashov, “Dobzhansky-Muller incompatibilities
in protein evolution,” PNAS, vol. 99, no. 23. National Academy of Sciences,
pp. 14878–14883, 2002.
ista: Kondrashov A, Sunyaev S, Kondrashov F. 2002. Dobzhansky-Muller incompatibilities
in protein evolution. PNAS. 99(23), 14878–14883.
mla: Kondrashov, Alexey, et al. “Dobzhansky-Muller Incompatibilities in Protein
Evolution.” PNAS, vol. 99, no. 23, National Academy of Sciences, 2002,
pp. 14878–83, doi:10.1073/pnas.232565499.
short: A. Kondrashov, S. Sunyaev, F. Kondrashov, PNAS 99 (2002) 14878–14883.
date_created: 2018-12-11T11:49:01Z
date_published: 2002-11-12T00:00:00Z
date_updated: 2023-07-26T09:48:37Z
day: '12'
doi: 10.1073/pnas.232565499
extern: '1'
external_id:
pmid:
- '12403824'
intvolume: ' 99'
issue: '23'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137512/
month: '11'
oa: 1
oa_version: Published Version
page: 14878 - 14883
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '6763'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dobzhansky-Muller incompatibilities in protein evolution
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 99
year: '2002'
...