[{"extern":"1","date_updated":"2026-05-18T09:07:29Z","external_id":{"pmid":["12573217"]},"doi":"10.1016/S0960-9822(03)00012-5","_id":"3922","oa_version":"Published Version","year":"2003","pmid":1,"issue":"3","publisher":"Elsevier","type":"journal_article","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T12:05:54Z","date_published":"2003-02-04T00:00:00Z","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/S0960-9822(03)00012-5"}],"quality_controlled":"1","day":"04","OA_type":"free access","title":"Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla ants","publication_status":"published","abstract":[{"lang":"eng","text":"Dispersal is advantageous, but, at the same time, it implies high costs and risks. Due to these counteracting selection pressures, many species evolved dispersal polymorphisms, which, in ants, are typically restricted to the female sex (queens). Male polymorphism is presently only known from a few genera, such as Cardiocondyla, in which winged dispersing males coexist with wingless fighter males that mate exclusively inside their maternal nests. We studied the developmental mechanisms underlying these alternative male morphs and found that, first, male dimorphism is not genetically determined, but is induced by environmental conditions (decreasing temperature and density). Second, male morph is not yet fixed at the egg stage, but it differentiates during larval development. This flexible developmental pattern of male morphs allows Cardiocondyla ant colonies to react quickly to changes in their environment. Under good conditions, they invest exclusively in philopatric wingless males. But, when environmental conditions turn bad, colonies start to produce winged dispersal males, even though these males require a many times higher investment by the colony than their much smaller wingless counterparts. Cardiocondyla ants share this potential of optimal resource allocation with other colonial animals and some seed dimorphic plants."}],"intvolume":"        13","OA_place":"publisher","publication":"Current Biology","month":"02","volume":13,"publist_id":"2234","oa":1,"article_processing_charge":"No","citation":{"ieee":"S. Cremer and J. Heinze, “Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla ants,” <i>Current Biology</i>, vol. 13, no. 3. Elsevier, pp. 219–223, 2003.","mla":"Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental Induction of Winged Dispersal Males in Cardiocondyla Ants.” <i>Current Biology</i>, vol. 13, no. 3, Elsevier, 2003, pp. 219–23, doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00012-5\">10.1016/S0960-9822(03)00012-5</a>.","short":"S. Cremer, J. Heinze, Current Biology 13 (2003) 219–223.","ama":"Cremer S, Heinze J. Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla ants. <i>Current Biology</i>. 2003;13(3):219-223. doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00012-5\">10.1016/S0960-9822(03)00012-5</a>","apa":"Cremer, S., &#38; Heinze, J. (2003). Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla ants. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0960-9822(03)00012-5\">https://doi.org/10.1016/S0960-9822(03)00012-5</a>","chicago":"Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental Induction of Winged Dispersal Males in Cardiocondyla Ants.” <i>Current Biology</i>. Elsevier, 2003. <a href=\"https://doi.org/10.1016/S0960-9822(03)00012-5\">https://doi.org/10.1016/S0960-9822(03)00012-5</a>.","ista":"Cremer S, Heinze J. 2003. Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla ants. Current Biology. 13(3), 219–223."},"page":"219 - 223","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-2193-3868","full_name":"Cremer, Sylvia","last_name":"Cremer","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia"},{"first_name":"Jürgen","last_name":"Heinze","full_name":"Heinze, Jürgen"}]},{"day":"17","quality_controlled":"1","intvolume":"      2598","abstract":[{"text":"We give analytic inclusion-exclusion formulas for the area and perimeter derivatives of a union of finitely many disks in the plane.","lang":"eng"}],"publication":"Computer Science in Perspective: Essays Dedicated to Thomas Ottmann","publication_status":"published","title":"Area and perimeter derivatives of a union of disks","publication_identifier":{"isbn":["9783540005797"]},"month":"02","scopus_import":"1","volume":2598,"language":[{"iso":"eng"}],"author":[{"first_name":"Ho","last_name":"Cheng","full_name":"Cheng, Ho"},{"last_name":"Edelsbrunner","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert","orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert"}],"citation":{"mla":"Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of a Union of Disks.” <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>, vol. 2598, Springer, 2003, pp. 88–97, doi:<a href=\"https://doi.org/10.1007/3-540-36477-3_7\">10.1007/3-540-36477-3_7</a>.","ieee":"H. Cheng and H. Edelsbrunner, “Area and perimeter derivatives of a union of disks,” in <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>, vol. 2598, Springer, 2003, pp. 88–97.","apa":"Cheng, H., &#38; Edelsbrunner, H. (2003). Area and perimeter derivatives of a union of disks. In <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i> (Vol. 2598, pp. 88–97). Springer. <a href=\"https://doi.org/10.1007/3-540-36477-3_7\">https://doi.org/10.1007/3-540-36477-3_7</a>","ama":"Cheng H, Edelsbrunner H. Area and perimeter derivatives of a union of disks. In: <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>. Vol 2598. Springer; 2003:88-97. doi:<a href=\"https://doi.org/10.1007/3-540-36477-3_7\">10.1007/3-540-36477-3_7</a>","ista":"Cheng H, Edelsbrunner H. 2003.Area and perimeter derivatives of a union of disks. In: Computer Science in Perspective: Essays Dedicated to Thomas Ottmann. LNCS, vol. 2598, 88–97.","chicago":"Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of a Union of Disks.” In <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>, 2598:88–97. Springer, 2003. <a href=\"https://doi.org/10.1007/3-540-36477-3_7\">https://doi.org/10.1007/3-540-36477-3_7</a>.","short":"H. Cheng, H. Edelsbrunner, in:, Computer Science in Perspective: Essays Dedicated to Thomas Ottmann, Springer, 2003, pp. 88–97."},"article_processing_charge":"No","page":"88 - 97","publist_id":"2132","acknowledgement":"Partially supported by NSF under grant DMS-98-73945 and CCR-00-86013.","extern":"1","date_updated":"2024-02-27T12:15:02Z","oa_version":"None","_id":"3991","alternative_title":["LNCS"],"doi":"10.1007/3-540-36477-3_7","publisher":"Springer","type":"book_chapter","year":"2003","date_published":"2003-02-17T00:00:00Z","status":"public","date_created":"2018-12-11T12:06:18Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17"},{"author":[{"full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner"},{"first_name":"Patrice","last_name":"Koehl","full_name":"Koehl, Patrice"}],"language":[{"iso":"eng"}],"page":"2203 - 2208","citation":{"short":"H. Edelsbrunner, P. Koehl, PNAS 100 (2003) 2203–2208.","ista":"Edelsbrunner H, Koehl P. 2003. The weighted-volume derivative of a space-filling diagram. PNAS. 100(5), 2203–2208.","chicago":"Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative of a Space-Filling Diagram.” <i>PNAS</i>. National Academy of Sciences, 2003. <a href=\"https://doi.org/10.1073/pnas.0537830100\">https://doi.org/10.1073/pnas.0537830100</a>.","ama":"Edelsbrunner H, Koehl P. The weighted-volume derivative of a space-filling diagram. <i>PNAS</i>. 2003;100(5):2203-2208. doi:<a href=\"https://doi.org/10.1073/pnas.0537830100\">10.1073/pnas.0537830100</a>","apa":"Edelsbrunner, H., &#38; Koehl, P. (2003). The weighted-volume derivative of a space-filling diagram. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.0537830100\">https://doi.org/10.1073/pnas.0537830100</a>","ieee":"H. Edelsbrunner and P. Koehl, “The weighted-volume derivative of a space-filling diagram,” <i>PNAS</i>, vol. 100, no. 5. National Academy of Sciences, pp. 2203–2208, 2003.","mla":"Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative of a Space-Filling Diagram.” <i>PNAS</i>, vol. 100, no. 5, National Academy of Sciences, 2003, pp. 2203–08, doi:<a href=\"https://doi.org/10.1073/pnas.0537830100\">10.1073/pnas.0537830100</a>."},"article_processing_charge":"No","oa":1,"publist_id":"2133","publication_identifier":{"issn":["0027-8424"]},"volume":100,"scopus_import":"1","month":"03","publication":"PNAS","abstract":[{"lang":"eng","text":"Computing the volume occupied by individual atoms in macromolecular structures has been the subject of research for several decades. This interest has grown in the recent years, because weighted volumes are widely used in implicit solvent models. Applications of the latter in molecular mechanics simulations require that the derivatives of these weighted volumes be known. In this article, we give a formula for the volume derivative of a molecule modeled as a space-filling diagram made up of balls in motion. The formula is given in terms of the weights, radii, and distances between the centers as well as the sizes of the facets of the power diagram restricted to the space-filling diagram. Special attention is given to the detection and treatment of singularities as well as discontinuities of the derivative."}],"intvolume":"       100","publication_status":"published","title":"The weighted-volume derivative of a space-filling diagram","day":"04","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151318/"}],"status":"public","date_published":"2003-03-04T00:00:00Z","date_created":"2018-12-11T12:06:19Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_type":"original","type":"journal_article","publisher":"National Academy of Sciences","issue":"5","pmid":1,"year":"2003","oa_version":"Published Version","_id":"3992","doi":"10.1073/pnas.0537830100","external_id":{"pmid":["12601153"]},"date_updated":"2024-02-27T12:31:59Z","extern":"1"},{"publisher":"Springer nature","type":"journal_article","article_type":"original","publication_identifier":{"eissn":["1432-0444"],"issnl":["0179-5376"]},"month":"05","year":"2003","volume":30,"language":[{"iso":"eng"}],"author":[{"first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833"},{"first_name":"John","last_name":"Harer","full_name":"Harer, John"},{"first_name":"Afra","last_name":"Zomorodian","full_name":"Zomorodian, Afra"}],"article_processing_charge":"No","date_published":"2003-05-01T00:00:00Z","citation":{"apa":"Edelsbrunner, H., Harer, J., &#38; Zomorodian, A. (2003). Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds. <i>Discrete &#38; Computational Geometry</i>. Springer nature. <a href=\"https://doi.org/10.1007/s00454-003-2926-5\">https://doi.org/10.1007/s00454-003-2926-5</a>","ama":"Edelsbrunner H, Harer J, Zomorodian A. Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds. <i>Discrete &#38; Computational Geometry</i>. 2003;30:87-107. doi:<a href=\"https://doi.org/10.1007/s00454-003-2926-5\">10.1007/s00454-003-2926-5</a>","ista":"Edelsbrunner H, Harer J, Zomorodian A. 2003. Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds. Discrete &#38; Computational Geometry. 30, 87–107.","chicago":"Edelsbrunner, Herbert, John Harer, and Afra Zomorodian. “Hierarchical Morse-Smale Complexes for Piecewise Linear 2-Manifolds.” <i>Discrete &#38; Computational Geometry</i>. Springer nature, 2003. <a href=\"https://doi.org/10.1007/s00454-003-2926-5\">https://doi.org/10.1007/s00454-003-2926-5</a>.","short":"H. Edelsbrunner, J. Harer, A. Zomorodian, Discrete &#38; Computational Geometry 30 (2003) 87–107.","mla":"Edelsbrunner, Herbert, et al. “Hierarchical Morse-Smale Complexes for Piecewise Linear 2-Manifolds.” <i>Discrete &#38; Computational Geometry</i>, vol. 30, Springer nature, 2003, pp. 87–107, doi:<a href=\"https://doi.org/10.1007/s00454-003-2926-5\">10.1007/s00454-003-2926-5</a>.","ieee":"H. Edelsbrunner, J. Harer, and A. Zomorodian, “Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds,” <i>Discrete &#38; Computational Geometry</i>, vol. 30. Springer nature, pp. 87–107, 2003."},"status":"public","page":"87 - 107","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publist_id":"2134","date_created":"2018-12-11T12:06:19Z","day":"01","extern":"1","date_updated":"2026-05-06T08:08:23Z","quality_controlled":"1","abstract":[{"lang":"eng","text":"We present algorithms for constructing a hierarchy of increasingly coarse Morse-Smale complexes that decompose a piecewise linear 2-manifold. While these complexes are defined only in the smooth category, we extend the construction to the piecewise linearcategory by ensuring structural integrity and simulating differentiability. We then simplify Morse-Smale complexes by canceling pairs of critical points in order of increasing persistence."}],"intvolume":"        30","oa_version":"None","publication":"Discrete & Computational Geometry","_id":"3993","title":"Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds","publication_status":"published","OA_type":"closed access","doi":"10.1007/s00454-003-2926-5"},{"publisher":"Elsevier","type":"journal_article","article_type":"original","issue":"2","year":"2003","date_published":"2003-10-01T00:00:00Z","status":"public","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2018-12-11T12:06:20Z","keyword":["Computational geometry","Differential geometry","Skin curves","Voronoi diagrams","Delaunay triangulations","Filtrations","Disks","Hyperbolas","Area","Perimeter","Derivatives"],"extern":"1","date_updated":"2026-05-06T08:12:09Z","oa_version":"None","_id":"3994","doi":"10.1016/S0925-7721(02)00124-4","month":"10","volume":26,"language":[{"iso":"eng"}],"author":[{"full_name":"Cheng, Ho","last_name":"Cheng","first_name":"Ho"},{"orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert"}],"citation":{"short":"H. Cheng, H. Edelsbrunner, Computational Geometry 26 (2003) 173–192.","chicago":"Cheng, Ho, and Herbert Edelsbrunner. “Area, Perimeter and Derivatives of a Skin Curve.” <i>Computational Geometry</i>. Elsevier, 2003. <a href=\"https://doi.org/10.1016/S0925-7721(02)00124-4\">https://doi.org/10.1016/S0925-7721(02)00124-4</a>.","ista":"Cheng H, Edelsbrunner H. 2003. Area, perimeter and derivatives of a skin curve. Computational Geometry. 26(2), 173–192.","apa":"Cheng, H., &#38; Edelsbrunner, H. (2003). Area, perimeter and derivatives of a skin curve. <i>Computational Geometry</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0925-7721(02)00124-4\">https://doi.org/10.1016/S0925-7721(02)00124-4</a>","ama":"Cheng H, Edelsbrunner H. Area, perimeter and derivatives of a skin curve. <i>Computational Geometry</i>. 2003;26(2):173-192. doi:<a href=\"https://doi.org/10.1016/S0925-7721(02)00124-4\">10.1016/S0925-7721(02)00124-4</a>","mla":"Cheng, Ho, and Herbert Edelsbrunner. “Area, Perimeter and Derivatives of a Skin Curve.” <i>Computational Geometry</i>, vol. 26, no. 2, Elsevier, 2003, pp. 173–92, doi:<a href=\"https://doi.org/10.1016/S0925-7721(02)00124-4\">10.1016/S0925-7721(02)00124-4</a>.","ieee":"H. Cheng and H. Edelsbrunner, “Area, perimeter and derivatives of a skin curve,” <i>Computational Geometry</i>, vol. 26, no. 2. Elsevier, pp. 173–192, 2003."},"article_processing_charge":"No","page":"173 - 192","publist_id":"2135","day":"01","quality_controlled":"1","abstract":[{"text":"The body defined by a finite collection of disks is a subset of the plane bounded by a tangent continuous curve, which we call the skin. We give analytic formulas for the area, the perimeter, the area derivative, and the perimeter derivative of the body. Given the filtrations of the Delaunay triangulation and the Voronoi diagram of the disks, all formulas can be evaluated in time proportional to the number of disks.","lang":"eng"}],"intvolume":"        26","publication":"Computational Geometry","publication_status":"published","title":"Area, perimeter and derivatives of a skin curve","OA_type":"closed access"},{"publication":"Proceedings of the 14th IEEE Conference on Visualization ","oa_version":"None","abstract":[{"text":"We combine topological and geometric methods to construct a multi-resolution data structure for functions over two-dimensional domains. Starting with the Morse-Smale complex, we construct a topological hierarchy by progressively canceling critical points in pairs. Concurrently, we create a geometric hierarchy by adapting the geometry to the changes in topology. The data structure supports mesh traversal operations similarly to traditional multi-resolution representations.","lang":"eng"}],"_id":"3997","publication_status":"published","title":"A multi-resolution data structure for two-dimensional Morse-Smale functions","doi":"10.1109/VISUAL.2003.1250365","day":"01","quality_controlled":"1","date_updated":"2024-02-27T11:12:50Z","extern":"1","author":[{"first_name":"Peer","last_name":"Bremer","full_name":"Bremer, Peer"},{"full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner"},{"last_name":"Hamann","first_name":"Bernd","full_name":"Hamann, Bernd"},{"full_name":"Pascucci, Valerio","first_name":"Valerio","last_name":"Pascucci"}],"language":[{"iso":"eng"}],"page":"139 - 146","status":"public","date_published":"2003-08-01T00:00:00Z","article_processing_charge":"No","citation":{"short":"P. Bremer, H. Edelsbrunner, B. Hamann, V. Pascucci, in:, Proceedings of the 14th IEEE Conference on Visualization , IEEE, 2003, pp. 139–146.","ista":"Bremer P, Edelsbrunner H, Hamann B, Pascucci V. 2003. A multi-resolution data structure for two-dimensional Morse-Smale functions. Proceedings of the 14th IEEE Conference on Visualization . VIS: IEEE Visualization, 139–146.","chicago":"Bremer, Peer, Herbert Edelsbrunner, Bernd Hamann, and Valerio Pascucci. “A Multi-Resolution Data Structure for Two-Dimensional Morse-Smale Functions.” In <i>Proceedings of the 14th IEEE Conference on Visualization </i>, 139–46. IEEE, 2003. <a href=\"https://doi.org/10.1109/VISUAL.2003.1250365\">https://doi.org/10.1109/VISUAL.2003.1250365</a>.","apa":"Bremer, P., Edelsbrunner, H., Hamann, B., &#38; Pascucci, V. (2003). A multi-resolution data structure for two-dimensional Morse-Smale functions. In <i>Proceedings of the 14th IEEE Conference on Visualization </i> (pp. 139–146). Seattle, WA, USA : IEEE. <a href=\"https://doi.org/10.1109/VISUAL.2003.1250365\">https://doi.org/10.1109/VISUAL.2003.1250365</a>","ama":"Bremer P, Edelsbrunner H, Hamann B, Pascucci V. A multi-resolution data structure for two-dimensional Morse-Smale functions. In: <i>Proceedings of the 14th IEEE Conference on Visualization </i>. IEEE; 2003:139-146. doi:<a href=\"https://doi.org/10.1109/VISUAL.2003.1250365\">10.1109/VISUAL.2003.1250365</a>","mla":"Bremer, Peer, et al. “A Multi-Resolution Data Structure for Two-Dimensional Morse-Smale Functions.” <i>Proceedings of the 14th IEEE Conference on Visualization </i>, IEEE, 2003, pp. 139–46, doi:<a href=\"https://doi.org/10.1109/VISUAL.2003.1250365\">10.1109/VISUAL.2003.1250365</a>.","ieee":"P. Bremer, H. Edelsbrunner, B. Hamann, and V. Pascucci, “A multi-resolution data structure for two-dimensional Morse-Smale functions,” in <i>Proceedings of the 14th IEEE Conference on Visualization </i>, Seattle, WA, USA , 2003, pp. 139–146."},"user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","publist_id":"2131","date_created":"2018-12-11T12:06:21Z","acknowledgement":"This work was performed under the auspices of the U. S. Department of Energy by University of California Lawrence Livermore National Laboratory under contract No. W-7405-Eng-48. H. Edelsbrunner is partially supported by the National Science Foundation (NFS) under grants EIA-99-72879 and CCR-00-86013. B. Hamann is supported by the NSF under contract ACI 9624034, through the LSSDSV program under contract ACI 9982251, and through the NPACI; the National Institute of Mental Health and the NSF under contract NIMH 2 P20 MH60975-06A2; the Lawrence Livermore National Laboratory under ASCI ASAP Level-2 Memorandum Agreement B347878 and under Memorandum Agreement B503159.","publication_identifier":{"isbn":["0780381203"]},"type":"conference","publisher":"IEEE","year":"2003","conference":{"location":"Seattle, WA, USA ","end_date":"2003-10-24","name":"VIS: IEEE Visualization","start_date":"2003-10-19"},"scopus_import":"1","month":"08"},{"conference":{"start_date":"2002-12-06","name":"JCDCG: Japanese Conference on Discrete and Computational Geometry","end_date":"2002-12-09","location":"Tokyo, Japan"},"year":"2003","type":"conference","publisher":"Springer","date_created":"2018-12-11T12:06:21Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","status":"public","date_published":"2003-12-16T00:00:00Z","date_updated":"2024-02-27T11:07:15Z","extern":"1","doi":"10.1007/978-3-540-44400-8_14","alternative_title":["LNCS"],"_id":"3999","oa_version":"None","volume":2866,"scopus_import":"1","month":"12","publication_identifier":{"isbn":["9783540207764"]},"acknowledgement":"NSF under grant CCR-00- 86013.","publist_id":"2127","page":"135 - 151","article_processing_charge":"No","citation":{"ieee":"H. Edelsbrunner and A. Üngör, “Relaxed scheduling in dynamic skin triangulation,” in <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry </i>, Tokyo, Japan, 2003, vol. 2866, pp. 135–151.","mla":"Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic Skin Triangulation.” <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry </i>, vol. 2866, Springer, 2003, pp. 135–51, doi:<a href=\"https://doi.org/10.1007/978-3-540-44400-8_14\">10.1007/978-3-540-44400-8_14</a>.","short":"H. Edelsbrunner, A. Üngör, in:, Proceedings of the Japanese Conference on Discrete and Computational Geometry , Springer, 2003, pp. 135–151.","apa":"Edelsbrunner, H., &#38; Üngör, A. (2003). Relaxed scheduling in dynamic skin triangulation. In <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry </i> (Vol. 2866, pp. 135–151). Tokyo, Japan: Springer. <a href=\"https://doi.org/10.1007/978-3-540-44400-8_14\">https://doi.org/10.1007/978-3-540-44400-8_14</a>","ama":"Edelsbrunner H, Üngör A. Relaxed scheduling in dynamic skin triangulation. In: <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry </i>. Vol 2866. Springer; 2003:135-151. doi:<a href=\"https://doi.org/10.1007/978-3-540-44400-8_14\">10.1007/978-3-540-44400-8_14</a>","chicago":"Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic Skin Triangulation.” In <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry </i>, 2866:135–51. Springer, 2003. <a href=\"https://doi.org/10.1007/978-3-540-44400-8_14\">https://doi.org/10.1007/978-3-540-44400-8_14</a>.","ista":"Edelsbrunner H, Üngör A. 2003. Relaxed scheduling in dynamic skin triangulation. Proceedings of the Japanese Conference on Discrete and Computational Geometry . JCDCG: Japanese Conference on Discrete and Computational Geometry, LNCS, vol. 2866, 135–151."},"author":[{"full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner"},{"first_name":"Alper","last_name":"Üngör","full_name":"Üngör, Alper"}],"language":[{"iso":"eng"}],"quality_controlled":"1","day":"16","publication_status":"published","title":"Relaxed scheduling in dynamic skin triangulation","publication":"Proceedings of the Japanese Conference on Discrete and Computational Geometry ","abstract":[{"text":"We introduce relaxed scheduling as a paradigm for mesh maintenance and demonstrate its applicability to triangulating a skin surface in R-3.","lang":"eng"}],"intvolume":"      2866"},{"type":"journal_article","article_type":"original","publisher":"Company of Biologists","year":"2003","issue":"22","pmid":1,"status":"public","date_published":"2003-11-15T00:00:00Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:13Z","date_updated":"2024-02-27T10:14:21Z","extern":"1","external_id":{"pmid":[" PMC1414802"]},"_id":"4146","oa_version":"None","doi":"10.1242/dev.00758","publication_identifier":{"issn":["1011-6370"]},"volume":130,"scopus_import":"1","month":"11","page":"5375 - 5384","article_processing_charge":"No","citation":{"chicago":"Ulrich, Florian, Miguel Concha, Paul Heid, Ed Voss, Sabine Witzel, Henry Roehl, Masazumi Tada, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and Morphogenesis at the Onset of Zebrafish Gastrulation.” <i>Development</i>. Company of Biologists, 2003. <a href=\"https://doi.org/10.1242/dev.00758\">https://doi.org/10.1242/dev.00758</a>.","ista":"Ulrich F, Concha M, Heid P, Voss E, Witzel S, Roehl H, Tada M, Wilson S, Adams R, Soll D, Heisenberg C-PJ. 2003. Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development. 130(22), 5375–5384.","ama":"Ulrich F, Concha M, Heid P, et al. Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. <i>Development</i>. 2003;130(22):5375-5384. doi:<a href=\"https://doi.org/10.1242/dev.00758\">10.1242/dev.00758</a>","apa":"Ulrich, F., Concha, M., Heid, P., Voss, E., Witzel, S., Roehl, H., … Heisenberg, C.-P. J. (2003). Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. <i>Development</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/dev.00758\">https://doi.org/10.1242/dev.00758</a>","short":"F. Ulrich, M. Concha, P. Heid, E. Voss, S. Witzel, H. Roehl, M. Tada, S. Wilson, R. Adams, D. Soll, C.-P.J. Heisenberg, Development 130 (2003) 5375–5384.","mla":"Ulrich, Florian, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and Morphogenesis at the Onset of Zebrafish Gastrulation.” <i>Development</i>, vol. 130, no. 22, Company of Biologists, 2003, pp. 5375–84, doi:<a href=\"https://doi.org/10.1242/dev.00758\">10.1242/dev.00758</a>.","ieee":"F. Ulrich <i>et al.</i>, “Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation,” <i>Development</i>, vol. 130, no. 22. Company of Biologists, pp. 5375–5384, 2003."},"author":[{"last_name":"Ulrich","first_name":"Florian","full_name":"Ulrich, Florian"},{"first_name":"Miguel","last_name":"Concha","full_name":"Concha, Miguel"},{"last_name":"Heid","first_name":"Paul","full_name":"Heid, Paul"},{"full_name":"Voss, Ed","first_name":"Ed","last_name":"Voss"},{"full_name":"Witzel, Sabine","first_name":"Sabine","last_name":"Witzel"},{"last_name":"Roehl","first_name":"Henry","full_name":"Roehl, Henry"},{"first_name":"Masazumi","last_name":"Tada","full_name":"Tada, Masazumi"},{"first_name":"Stephen","last_name":"Wilson","full_name":"Wilson, Stephen"},{"last_name":"Adams","first_name":"Richard","full_name":"Adams, Richard"},{"full_name":"Soll, David","first_name":"David","last_name":"Soll"},{"last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J"}],"language":[{"iso":"eng"}],"acknowledgement":"We thank Jennifer Geiger, Mathias Köppen, Christian Dahmann and Marcos Gonzalez-Gaitan for helpful comments on earlier versions of this manuscript,Beate Kilian for technical assistance, Ugur Yalcin, Katrin Anczok and Viktor Schnabel for help with the image analysis, Vinzenz Link for programming Excel Macros and Harald Brush-Janovjak for extensive reviews of the statistics part of this work. We are grateful to Kurt Anderson and Jan Peychl for help with the confocal microscopy. P.J.H., E.V. and D.R.S. are supported by NIH grant HD-18577, The W.M Keck Foundation and the Developmental Studies Hybridoma Bank(DSHB), P.J.H. by The American Cancer Society (grant # PF-01-110-01-CSM),M.L.C. and S.W.W. by the Wellcome Trust, M.T. by an MRC Career Development Award, and F.U. and C.P.H. by an Emmy-Noether-Fellowship from the DFG.","oa":1,"publist_id":"1975","quality_controlled":"1","day":"15","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414802/"}],"title":"Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation","publication_status":"published","publication":"Development","abstract":[{"lang":"eng","text":"During vertebrate gastrulation, highly coordinated cellular rearrangements lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm. In zebrafish, silberblick (slb)/wnt11 regulates normal gastrulation movements by activating a signalling pathway similar to the Frizzled-signalling pathway, which establishes epithelial planar cell polarity (PCP) in Drosophila. However, the cellular mechanisms by which slb/wnt11 functions during zebrafish gastrulation are still unclear. Using high-resolution two-photon confocal imaging followed by computer-assisted reconstruction and motion analysis, we have analysed the movement and morphology of individual cells in three dimensions during the course of gastrulation. We show that in slb-mutant embryos, hypoblast cells within the forming germ ring have slower, less directed migratory movements at the onset of gastrulation. These aberrant cell movements are accompanied by defects in the orientation of cellular processes along the individual movement directions of these cells. We conclude that slb/wnt11-mediated orientation of cellular processes plays a role in facilitating and stabilising movements of hypoblast cells in the germ ring, thereby pointing at a novel function of the slb/wnt11 signalling pathway for the regulation of migratory cell movements at early stages of gastrulation."}],"intvolume":"       130"},{"day":"01","quality_controlled":"1","publication":"Developmental Cell","intvolume":"         5","abstract":[{"text":"Recent studies show that signaling through integrin receptors is required for normal cell movements during Xenopus gastrulation. Integrins function in this process by modulating the activity of cadherin adhesion molecules within tissues undergoing convergence and extension movements.","lang":"eng"}],"publication_status":"published","title":"Adhesive crosstalk in gastrulation","volume":5,"month":"08","scopus_import":"1","publication_identifier":{"issn":["1534-5807"],"eissn":["1878-1551"]},"publist_id":"1949","author":[{"first_name":"Juan","last_name":"Montero","full_name":"Montero, Juan"},{"last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J"}],"language":[{"iso":"eng"}],"page":"190 - 191","citation":{"apa":"Montero, J., &#38; Heisenberg, C.-P. J. (2003). Adhesive crosstalk in gastrulation. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/S1534-5807(03)00235-1\">https://doi.org/10.1016/S1534-5807(03)00235-1</a>","ama":"Montero J, Heisenberg C-PJ. Adhesive crosstalk in gastrulation. <i>Developmental Cell</i>. 2003;5(2):190-191. doi:<a href=\"https://doi.org/10.1016/S1534-5807(03)00235-1\">10.1016/S1534-5807(03)00235-1</a>","ista":"Montero J, Heisenberg C-PJ. 2003. Adhesive crosstalk in gastrulation. Developmental Cell. 5(2), 190–191.","chicago":"Montero, Juan, and Carl-Philipp J Heisenberg. “Adhesive Crosstalk in Gastrulation.” <i>Developmental Cell</i>. Cell Press, 2003. <a href=\"https://doi.org/10.1016/S1534-5807(03)00235-1\">https://doi.org/10.1016/S1534-5807(03)00235-1</a>.","short":"J. Montero, C.-P.J. Heisenberg, Developmental Cell 5 (2003) 190–191.","mla":"Montero, Juan, and Carl-Philipp J. Heisenberg. “Adhesive Crosstalk in Gastrulation.” <i>Developmental Cell</i>, vol. 5, no. 2, Cell Press, 2003, pp. 190–91, doi:<a href=\"https://doi.org/10.1016/S1534-5807(03)00235-1\">10.1016/S1534-5807(03)00235-1</a>.","ieee":"J. Montero and C.-P. J. Heisenberg, “Adhesive crosstalk in gastrulation,” <i>Developmental Cell</i>, vol. 5, no. 2. Cell Press, pp. 190–191, 2003."},"article_processing_charge":"No","external_id":{"pmid":["12919669 "]},"date_updated":"2024-02-27T09:54:53Z","extern":"1","doi":"10.1016/S1534-5807(03)00235-1","oa_version":"None","_id":"4168","pmid":1,"issue":"2","year":"2003","type":"journal_article","article_type":"original","publisher":"Cell Press","date_created":"2018-12-11T12:07:21Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","status":"public","date_published":"2003-08-01T00:00:00Z"},{"day":"05","quality_controlled":"1","intvolume":"        13","abstract":[{"text":"Background: During vertebrate gastrulation, cell polarization and migration are core components in the cellular rearrangements that lead to the formation of the three germ layers, ectoderm, mesoderm, and endoderm. Previous studies have implicated the Wnt/planar cell polarity (PCP) signaling pathway in controlling cell morphology and movement during gastrulation. However, cell polarization and directed cell migration are reduced but not completely abolished in the absence of Wnt/PCP signals; this observation indicates that other signaling pathways must be involved. Results: We show that Phosphoinositide 3-Kinases (PI3Ks) are required at the onset of zebrafish gastrulation in mesendodermal cells for process formation and cell polarization. Platelet Derived Growth Factor (PDGF) functions upstream of PI3K, while Protein Kinase B (PKB), a downstream effector of PI3K activity, localizes to the leading edge of migrating mesendodermal cells. In the absence of PI3K activity, PKB localization and cell polarization are strongly reduced in mesendodermal cells and are followed by slower but still highly coordinated and directed movements of these cells. Conclusions: We have identified a novel role of a signaling pathway comprised of PDGF, PI3K, and PKB in the control of morphogenetic cell movements during gastrulation. Furthermore, our findings provide insight into the relationship between cell polarization and directed cell migration at the onset of zebrafish gastrulation.","lang":"eng"}],"publication":"Current Biology","title":"Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells","publication_status":"published","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"scopus_import":"1","month":"08","volume":13,"language":[{"iso":"eng"}],"author":[{"full_name":"Montero, Juan","last_name":"Montero","first_name":"Juan"},{"last_name":"Kilian","first_name":"Beate","full_name":"Kilian, Beate"},{"first_name":"Joanne","last_name":"Chan","full_name":"Chan, Joanne"},{"last_name":"Bayliss","first_name":"Peter","full_name":"Bayliss, Peter"},{"id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566"}],"article_processing_charge":"No","citation":{"ieee":"J. Montero, B. Kilian, J. Chan, P. Bayliss, and C.-P. J. Heisenberg, “Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells,” <i>Current Biology</i>, vol. 13, no. 15. Cell Press, pp. 1279–1289, 2003.","mla":"Montero, Juan, et al. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth and Cell Polarization of Gastrulating Mesendodermal Cells.” <i>Current Biology</i>, vol. 13, no. 15, Cell Press, 2003, pp. 1279–89, doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00505-0\">10.1016/S0960-9822(03)00505-0</a>.","short":"J. Montero, B. Kilian, J. Chan, P. Bayliss, C.-P.J. Heisenberg, Current Biology 13 (2003) 1279–1289.","chicago":"Montero, Juan, Beate Kilian, Joanne Chan, Peter Bayliss, and Carl-Philipp J Heisenberg. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth and Cell Polarization of Gastrulating Mesendodermal Cells.” <i>Current Biology</i>. Cell Press, 2003. <a href=\"https://doi.org/10.1016/S0960-9822(03)00505-0\">https://doi.org/10.1016/S0960-9822(03)00505-0</a>.","ista":"Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. 2003. Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. Current Biology. 13(15), 1279–1289.","ama":"Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. <i>Current Biology</i>. 2003;13(15):1279-1289. doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00505-0\">10.1016/S0960-9822(03)00505-0</a>","apa":"Montero, J., Kilian, B., Chan, J., Bayliss, P., &#38; Heisenberg, C.-P. J. (2003). Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/S0960-9822(03)00505-0\">https://doi.org/10.1016/S0960-9822(03)00505-0</a>"},"page":"1279 - 1289","publist_id":"1950","acknowledgement":"We would like to thank Jennifer Geiger, Juan Hurl& Hannu Mansu-koski, Florian Raible, Marino Zerial, Steve Wilson, and Kurt Anderson for critical reading of earlier versions of this manuscript. We thank Erez Raz, Bart Vanhaesebroeck, and Lukas Roth for sending us the pCS2-PH-GFP-nos, the p1IOCAAX, and the pCS2-actin-GFP constructs, respectively. We are grateful to Marino Zerial and his lab for encouraging us to start this work and providing us with the dnP13K construct and to Florian Ulrich and Franziska Friedrich for help with the confocal microscope and artwork, respectively. We thank Gunter Junghanns and Evelyn Lehmann for excellent fish care. C.-P.H. is supported by an Emmy-Noother-Fellowship from the Deutsche Forschungsgemeinschaft. ","external_id":{"pmid":[" 12906787"]},"extern":"1","date_updated":"2024-02-27T10:03:37Z","oa_version":"None","_id":"4169","doi":"10.1016/S0960-9822(03)00505-0","publisher":"Cell Press","type":"journal_article","article_type":"original","pmid":1,"issue":"15","year":"2003","date_published":"2003-08-05T00:00:00Z","status":"public","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:22Z"},{"publication":"Mechanisms of Development","abstract":[{"text":"Wnt genes play important roles in regulating patterning and morphogenesis during vertebrate gastrulation. In zebrafish, slb/wnt11 is required for convergence and extension movements, but not cell fate specification during gastrulation. To determine if other Wnt genes functionally interact with slb/wnt11, we analysed the role of ppt/wnt5 during zebrafish gastrulation. ppt/wnt5 is maternally provided and zygotically expressed at all stages during gastrulation. The analysis of ppt mutant embryos reveals that Ppt/Wnt5 regulates cell elongation and convergent extension movements in posterior regions of the gastrula, while its function in more anterior regions is largely redundant to that of Slb/Wnt11. Frizzled-2 functions downstream of ppt/wnt5, indicating that it might act as a receptor for Ppt/Wnt5 in this process. The characterisation of the role of Ppt/Wnt5 provides insight into the functional diversity of Wnt genes in regulating vertebrate gastrulation movements. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.","lang":"eng"}],"intvolume":"       120","title":"The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation","publication_status":"published","day":"01","quality_controlled":"1","author":[{"last_name":"Kilian","first_name":"Beate","full_name":"Kilian, Beate"},{"full_name":"Mansukoski, Hannu","first_name":"Hannu","last_name":"Mansukoski"},{"first_name":"Filipa","last_name":"Barbosa","full_name":"Barbosa, Filipa"},{"first_name":"Florian","last_name":"Ulrich","full_name":"Ulrich, Florian"},{"full_name":"Tada, Masazumi","first_name":"Masazumi","last_name":"Tada"},{"full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","last_name":"Heisenberg"}],"language":[{"iso":"eng"}],"page":"467 - 476","citation":{"ista":"Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. 2003. The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mechanisms of Development. 120(4), 467–476.","chicago":"Kilian, Beate, Hannu Mansukoski, Filipa Barbosa, Florian Ulrich, Masazumi Tada, and Carl-Philipp J Heisenberg. “The Role of Ppt/Wnt5 in Regulating Cell Shape and Movement during Zebrafish Gastrulation.” <i>Mechanisms of Development</i>. Elsevier, 2003. <a href=\"https://doi.org/10.1016/S0925-4773(03)00004-2\">https://doi.org/10.1016/S0925-4773(03)00004-2</a>.","apa":"Kilian, B., Mansukoski, H., Barbosa, F., Ulrich, F., Tada, M., &#38; Heisenberg, C.-P. J. (2003). The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. <i>Mechanisms of Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0925-4773(03)00004-2\">https://doi.org/10.1016/S0925-4773(03)00004-2</a>","ama":"Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. <i>Mechanisms of Development</i>. 2003;120(4):467-476. doi:<a href=\"https://doi.org/10.1016/S0925-4773(03)00004-2\">10.1016/S0925-4773(03)00004-2</a>","short":"B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, C.-P.J. Heisenberg, Mechanisms of Development 120 (2003) 467–476.","ieee":"B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, and C.-P. J. Heisenberg, “The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation,” <i>Mechanisms of Development</i>, vol. 120, no. 4. Elsevier, pp. 467–476, 2003.","mla":"Kilian, Beate, et al. “The Role of Ppt/Wnt5 in Regulating Cell Shape and Movement during Zebrafish Gastrulation.” <i>Mechanisms of Development</i>, vol. 120, no. 4, Elsevier, 2003, pp. 467–76, doi:<a href=\"https://doi.org/10.1016/S0925-4773(03)00004-2\">10.1016/S0925-4773(03)00004-2</a>."},"article_processing_charge":"No","publist_id":"1934","acknowledgement":"We thank Michael Brand, Florian Raible, Gerlinde Reim, Tobias Langenberg, Jennifer Geiger and Kate Poole for helpful comments on earlier versions of this manuscript. We are grateful to Henry Roehl and Christiane Nüsslein Volhard for sending us the ppt mutant stock. M.T. was supported by a Career Development Fellowship from the MRC. B.K., H.M. and C.P.H. are supported by an Emmy Noether-Fellowship from the DFG.","publication_identifier":{"issn":["0925-4773"]},"volume":120,"month":"04","scopus_import":"1","oa_version":"None","_id":"4185","doi":"10.1016/S0925-4773(03)00004-2","external_id":{"pmid":["12676324 "]},"date_updated":"2024-02-27T09:46:39Z","extern":"1","status":"public","date_published":"2003-04-01T00:00:00Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:27Z","type":"journal_article","article_type":"original","publisher":"Elsevier","pmid":1,"issue":"4","year":"2003"},{"language":[{"iso":"eng"}],"author":[{"full_name":"Navarro, Arcadio","first_name":"Arcadio","last_name":"Navarro"},{"last_name":"Barton","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H"}],"article_processing_charge":"No","citation":{"mla":"Navarro, Arcadio, and Nicholas H. Barton. “Accumulating Postzygotic Isolation Genes in Parapatry: A New Twist on Chromosomal Speciation.” <i>Evolution; International Journal of Organic Evolution</i>, vol. 57, no. 3, Wiley-Blackwell, 2003, pp. 447–59, doi:<a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb01537.x\">10.1111/j.0014-3820.2003.tb01537.x</a>.","ieee":"A. Navarro and N. H. Barton, “Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation,” <i>Evolution; International Journal of Organic Evolution</i>, vol. 57, no. 3. Wiley-Blackwell, pp. 447–459, 2003.","ama":"Navarro A, Barton NH. Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation. <i>Evolution; International Journal of Organic Evolution</i>. 2003;57(3):447-459. doi:<a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb01537.x\">10.1111/j.0014-3820.2003.tb01537.x</a>","apa":"Navarro, A., &#38; Barton, N. H. (2003). Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation. <i>Evolution; International Journal of Organic Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb01537.x\">https://doi.org/10.1111/j.0014-3820.2003.tb01537.x</a>","chicago":"Navarro, Arcadio, and Nicholas H Barton. “Accumulating Postzygotic Isolation Genes in Parapatry: A New Twist on Chromosomal Speciation.” <i>Evolution; International Journal of Organic Evolution</i>. Wiley-Blackwell, 2003. <a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb01537.x\">https://doi.org/10.1111/j.0014-3820.2003.tb01537.x</a>.","ista":"Navarro A, Barton NH. 2003. Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation. Evolution; International Journal of Organic Evolution. 57(3), 447–459.","short":"A. Navarro, N.H. Barton, Evolution; International Journal of Organic Evolution 57 (2003) 447–459."},"page":"447 - 459","publist_id":"1840","acknowledgement":"We thank A. Andrés, C. Bartolomé, J. Bertranpetit, F. Calafell, B. Charlesworth, D. Charlesworth, F. Depaulis, S. Gavrilets, T. Johnson, P. Keightley, M. Kirkpatrik, A. Kondrashov, H. Laayouni, X. Maside, M. Noor, D. Ortiz-Barrientos,\r\nL. Rieseberg, and T. Vines for valuable discussion and criticism. The detailed comments of B. Charlesworth, D. Charlesworth, and F. Depaulis greatly improved the original manuscript. AN is particularly grateful to X. Maside, who was a patient guide through the jungle of speciation. This work was supported by the NERC grant GR3/11635 (United Kingdom). AN is funded by the Ramón y Cajal Program (Spain).","publication_identifier":{"issn":["0014-3820"]},"scopus_import":"1","month":"03","volume":57,"abstract":[{"lang":"eng","text":"Chromosomal rearrangements can promote reproductive isolation by reducing recombination along a large section of the genome. We model the effects of the genetic barrier to gene flow caused by a chromosomal rearrangement on the rate of accumulation of postzygotic isolation genes in parapatry. We find that, if reproductive isolation is produced by the accumulation in parapatry of sets of alleles compatible within but incompatible across species, chromosomal rearrangements are far more likely to favor it than classical genetic barriers without chromosomal changes. New evidence of the role of chromosomal rearrangements in parapatric speciation suggests that postzygotic isolation is often due to the accumulation of such incompatibilities. The model makes testable qualitative predictions about the genetic signature of speciation."}],"intvolume":"        57","publication":"Evolution; International Journal of Organic Evolution","publication_status":"published","title":"Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation","day":"01","quality_controlled":"1","date_published":"2003-03-01T00:00:00Z","status":"public","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:52Z","publisher":"Wiley-Blackwell","type":"journal_article","article_type":"original","issue":"3","pmid":1,"year":"2003","oa_version":"None","_id":"4254","doi":"10.1111/j.0014-3820.2003.tb01537.x","external_id":{"pmid":["12703935 "]},"extern":"1","date_updated":"2024-01-23T10:21:57Z"},{"doi":"10.1126/science.1080600 ","_id":"4255","oa_version":"None","date_updated":"2024-02-26T13:37:51Z","extern":"1","external_id":{"pmid":[" 12690198"]},"user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:53Z","status":"public","date_published":"2003-04-11T00:00:00Z","year":"2003","pmid":1,"issue":"5617","article_type":"original","type":"journal_article","publisher":"American Association for the Advancement of Science","publication_status":"published","title":"Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes","publication":"Science","intvolume":"       300","abstract":[{"text":"Humans and their closest evolutionary relatives, the chimpanzees, differ in ∼1.24% of their genomic DNA sequences. The fraction of these changes accumulated during the speciation processes that have separated the two lineages may be of special relevance in understanding the basis of their differences. We analyzed human and chimpanzee sequence data to search for the patterns of divergence and polymorphism predicted by a theoretical model of speciation. According to the model, positively selected changes should accumulate in chromosomes that present fixed structural differences, such as inversions, between the two species. Protein evolution was more than 2.2 times faster in chromosomes that had undergone structural rearrangements compared with colinear chromosomes. Also, nucleotide variability is slightly lower in rearranged chromosomes. These patterns of divergence and polymorphism may be, at least in part, the molecular footprint of speciation events in the human and chimpanzee lineages. ","lang":"eng"}],"quality_controlled":"1","day":"11","publist_id":"1841","page":"321 - 324","article_processing_charge":"No","citation":{"short":"A. Navarro, N.H. Barton, Science 300 (2003) 321–324.","chicago":"Navarro, Arcadio, and Nicholas H Barton. “Chromosomal Speciation and Molecular Divergence -- Accelerated Evolution in Rearranged Chromosomes.” <i>Science</i>. American Association for the Advancement of Science, 2003. <a href=\"https://doi.org/10.1126/science.1080600 \">https://doi.org/10.1126/science.1080600 </a>.","ista":"Navarro A, Barton NH. 2003. Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. Science. 300(5617), 321–324.","apa":"Navarro, A., &#38; Barton, N. H. (2003). Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1080600 \">https://doi.org/10.1126/science.1080600 </a>","ama":"Navarro A, Barton NH. Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. <i>Science</i>. 2003;300(5617):321-324. doi:<a href=\"https://doi.org/10.1126/science.1080600 \">10.1126/science.1080600 </a>","ieee":"A. Navarro and N. H. Barton, “Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes,” <i>Science</i>, vol. 300, no. 5617. American Association for the Advancement of Science, pp. 321–324, 2003.","mla":"Navarro, Arcadio, and Nicholas H. Barton. “Chromosomal Speciation and Molecular Divergence -- Accelerated Evolution in Rearranged Chromosomes.” <i>Science</i>, vol. 300, no. 5617, American Association for the Advancement of Science, 2003, pp. 321–24, doi:<a href=\"https://doi.org/10.1126/science.1080600 \">10.1126/science.1080600 </a>."},"author":[{"full_name":"Navarro, Arcadio","last_name":"Navarro","first_name":"Arcadio"},{"full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","last_name":"Barton"}],"language":[{"iso":"eng"}],"volume":300,"month":"04","scopus_import":"1","publication_identifier":{"issn":["0036-8075"]}},{"publication_identifier":{"issn":["0960-9822"]},"scopus_import":"1","month":"08","volume":13,"citation":{"ieee":"N. H. Barton and W. Zuidema, “The erratic path towards complexity,” <i>Current Biology</i>, vol. 13, no. 16. Cell Press, pp. R649–R651, 2003.","mla":"Barton, Nicholas H., and Willem Zuidema. “The Erratic Path towards Complexity.” <i>Current Biology</i>, vol. 13, no. 16, Cell Press, 2003, pp. R649–51, doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00573-6\">10.1016/S0960-9822(03)00573-6</a>.","short":"N.H. Barton, W. Zuidema, Current Biology 13 (2003) R649–R651.","ama":"Barton NH, Zuidema W. The erratic path towards complexity. <i>Current Biology</i>. 2003;13(16):R649-R651. doi:<a href=\"https://doi.org/10.1016/S0960-9822(03)00573-6\">10.1016/S0960-9822(03)00573-6</a>","apa":"Barton, N. H., &#38; Zuidema, W. (2003). The erratic path towards complexity. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/S0960-9822(03)00573-6\">https://doi.org/10.1016/S0960-9822(03)00573-6</a>","ista":"Barton NH, Zuidema W. 2003. The erratic path towards complexity. Current Biology. 13(16), R649–R651.","chicago":"Barton, Nicholas H, and Willem Zuidema. “The Erratic Path towards Complexity.” <i>Current Biology</i>. Cell Press, 2003. <a href=\"https://doi.org/10.1016/S0960-9822(03)00573-6\">https://doi.org/10.1016/S0960-9822(03)00573-6</a>."},"article_processing_charge":"No","page":"R649 - R651","language":[{"iso":"eng"}],"author":[{"full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton"},{"full_name":"Zuidema, Willem","first_name":"Willem","last_name":"Zuidema"}],"publist_id":"1838","quality_controlled":"1","day":"19","publication_status":"published","title":"The erratic path towards complexity","intvolume":"        13","abstract":[{"lang":"eng","text":"Artificial Life models may shed new light on the long-standing challenge for evolutionary biology of explaining the origins of complex organs. Real progress on this issue, however, requires Artificial Life researchers to take seriously the tools and insights from population genetics."}],"publication":"Current Biology","publisher":"Cell Press","type":"journal_article","article_type":"original","year":"2003","issue":"16","date_published":"2003-08-19T00:00:00Z","status":"public","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:53Z","extern":"1","date_updated":"2024-01-23T09:41:33Z","_id":"4256","oa_version":"Published Version","doi":"10.1016/S0960-9822(03)00573-6"},{"page":"99 - 125","status":"public","citation":{"mla":"Charlesworth, Brian, et al. “The Effects of Genetic and Geographic Structure on Neutral Variation.” <i>Annual Review of Ecology and Systematics</i>, vol. 34, Annual Reviews, 2003, pp. 99–125, doi:<a href=\"https://doi.org/10.1146/annurev.ecolsys.34.011802.132359\">10.1146/annurev.ecolsys.34.011802.132359</a>.","ieee":"B. Charlesworth, D. Charlesworth, and N. H. Barton, “The effects of genetic and geographic structure on neutral variation,” <i>Annual Review of Ecology and Systematics</i>, vol. 34. Annual Reviews, pp. 99–125, 2003.","ista":"Charlesworth B, Charlesworth D, Barton NH. 2003. The effects of genetic and geographic structure on neutral variation. Annual Review of Ecology and Systematics. 34, 99–125.","chicago":"Charlesworth, Brian, Deborah Charlesworth, and Nicholas H Barton. “The Effects of Genetic and Geographic Structure on Neutral Variation.” <i>Annual Review of Ecology and Systematics</i>. Annual Reviews, 2003. <a href=\"https://doi.org/10.1146/annurev.ecolsys.34.011802.132359\">https://doi.org/10.1146/annurev.ecolsys.34.011802.132359</a>.","ama":"Charlesworth B, Charlesworth D, Barton NH. The effects of genetic and geographic structure on neutral variation. <i>Annual Review of Ecology and Systematics</i>. 2003;34:99-125. doi:<a href=\"https://doi.org/10.1146/annurev.ecolsys.34.011802.132359\">10.1146/annurev.ecolsys.34.011802.132359</a>","apa":"Charlesworth, B., Charlesworth, D., &#38; Barton, N. H. (2003). The effects of genetic and geographic structure on neutral variation. <i>Annual Review of Ecology and Systematics</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev.ecolsys.34.011802.132359\">https://doi.org/10.1146/annurev.ecolsys.34.011802.132359</a>","short":"B. Charlesworth, D. Charlesworth, N.H. Barton, Annual Review of Ecology and Systematics 34 (2003) 99–125."},"date_published":"2003-11-01T00:00:00Z","article_processing_charge":"No","author":[{"last_name":"Charlesworth","first_name":"Brian","full_name":"Charlesworth, Brian"},{"full_name":"Charlesworth, Deborah","first_name":"Deborah","last_name":"Charlesworth"},{"orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H"}],"language":[{"iso":"eng"}],"publist_id":"1839","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:53Z","publication_identifier":{"issn":["1543-592X"]},"type":"journal_article","article_type":"original","publisher":"Annual Reviews","year":"2003","volume":34,"month":"11","_id":"4257","publication_status":"published","title":"The effects of genetic and geographic structure on neutral variation","publication":"Annual Review of Ecology and Systematics","oa_version":"None","abstract":[{"lang":"eng","text":"Variation within a species may be structured both geographically and by genetic background. We review the effects of such structuring on neutral variants, using a framework based on the coalescent process. Short-term effects of sex differences and age structure can be averaged out using fast timescale approximations, allowing a simple general treatment of effective population size and migration. We consider the effects of geographic structure on variation within and between local populations, first in general terms, and then for specific migration models. We discuss the close parallels between geographic structure and stable types of genetic structure caused by selection, including balancing selection and background selection. The effects of departures from stability, such as selective sweeps and population bottlenecks, are also described. Methods for distinguishing population history from the effects of ongoing gene flow are discussed. We relate the theoretical results to observed patterns of variation in natural populations."}],"intvolume":"        34","doi":"10.1146/annurev.ecolsys.34.011802.132359","date_updated":"2024-01-23T10:15:44Z","quality_controlled":"1","extern":"1","day":"01"},{"oa_version":"None","_id":"4338","doi":"10.1111/j.0014-3820.2003.tb00595.x","extern":"1","date_updated":"2024-01-23T09:16:43Z","date_published":"2003-08-01T00:00:00Z","status":"public","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:08:20Z","publisher":"Wiley-Blackwell","article_type":"original","type":"journal_article","issue":"8","year":"2003","abstract":[{"text":"Mosaic hybrid zones arise when ecologically differentiated taxa hybridize across a network of habitat patches. Frequent interbreeding across a small-scale patchwork can erode species differences that might have been preserved in a clinal hybrid zone. In particular, the rapid breakdown of neutral divergence sets an upper limit to the time for which differences at marker loci can persist. We present here a case study of a mosaic hybrid zone between the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae) near Apahida in Romania. In our 20 × 20 km study area, we detected no evidence of a clinal transition but found a strong association between aquatic habitat and mean allele frequencies at four molecular markers. In particular, pure populations of B. bombina in ponds appear to cause massive introgression into the surrounding B. variegata gene pool found in temporary aquatic sites. Nevertheless, the genetic structure of these hybrid populations was remarkably similar to those of a previously studied transect near Pescenica (Croatia), which had both clinal and mosaic features: estimates of heterozygote deficit and linkage disequilibrium in each country are similar. In Apahida, the observed strong linkage disequilibria should stem from an imperfect habitat preference that guides most (but not all) adults into the habitats to which they are adapted. In the absence of a clinal structure, the inferred migration rate between habitats implies that associations between selected loci and neutral markers should break down rapidly. Although plausible selection strengths can maintain differentiation at those loci adapting the toads to either permanent or temporary breeding sites, the divergence at neutral markers must be transient. The hybrid zone may be approaching a state in which the gene pools are homogenized at all but the selected loci, not dissimilar from an early stage of sympatric divergence.","lang":"eng"}],"intvolume":"        57","publication":"Evolution","publication_status":"published","title":"On the maintenance of reproductive isolation in a mosaic hybrid zone between the toads Bombina bombina and B. variegata","day":"01","quality_controlled":"1","language":[{"iso":"eng"}],"author":[{"first_name":"Timothy","last_name":"Vines","full_name":"Vines, Timothy"},{"last_name":"Kohler","first_name":"S C","full_name":"Kohler, S C"},{"first_name":"M","last_name":"Thiel","full_name":"Thiel, M"},{"full_name":"Ghira, Ioan","first_name":"Ioan","last_name":"Ghira"},{"last_name":"Sands","first_name":"T R","full_name":"Sands, T R"},{"first_name":"Catriona","last_name":"Maccallum","full_name":"Maccallum, Catriona"},{"orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H"},{"first_name":"Beate","last_name":"Nürnberger","full_name":"Nürnberger, Beate"}],"citation":{"mla":"Vines, Timothy, et al. “On the Maintenance of Reproductive Isolation in a Mosaic Hybrid Zone between the Toads Bombina Bombina and B. Variegata.” <i>Evolution</i>, vol. 57, no. 8, Wiley-Blackwell, 2003, pp. 1876–88, doi:<a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb00595.x\">10.1111/j.0014-3820.2003.tb00595.x</a>.","ieee":"T. Vines <i>et al.</i>, “On the maintenance of reproductive isolation in a mosaic hybrid zone between the toads Bombina bombina and B. variegata,” <i>Evolution</i>, vol. 57, no. 8. Wiley-Blackwell, pp. 1876–1888, 2003.","chicago":"Vines, Timothy, S C Kohler, M Thiel, Ioan Ghira, T R Sands, Catriona Maccallum, Nicholas H Barton, and Beate Nürnberger. “On the Maintenance of Reproductive Isolation in a Mosaic Hybrid Zone between the Toads Bombina Bombina and B. Variegata.” <i>Evolution</i>. Wiley-Blackwell, 2003. <a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb00595.x\">https://doi.org/10.1111/j.0014-3820.2003.tb00595.x</a>.","ista":"Vines T, Kohler SC, Thiel M, Ghira I, Sands TR, Maccallum C, Barton NH, Nürnberger B. 2003. On the maintenance of reproductive isolation in a mosaic hybrid zone between the toads Bombina bombina and B. variegata. Evolution. 57(8), 1876–1888.","apa":"Vines, T., Kohler, S. C., Thiel, M., Ghira, I., Sands, T. R., Maccallum, C., … Nürnberger, B. (2003). On the maintenance of reproductive isolation in a mosaic hybrid zone between the toads Bombina bombina and B. variegata. <i>Evolution</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb00595.x\">https://doi.org/10.1111/j.0014-3820.2003.tb00595.x</a>","ama":"Vines T, Kohler SC, Thiel M, et al. On the maintenance of reproductive isolation in a mosaic hybrid zone between the toads Bombina bombina and B. variegata. <i>Evolution</i>. 2003;57(8):1876-1888. doi:<a href=\"https://doi.org/10.1111/j.0014-3820.2003.tb00595.x\">10.1111/j.0014-3820.2003.tb00595.x</a>","short":"T. Vines, S.C. Kohler, M. Thiel, I. Ghira, T.R. Sands, C. Maccallum, N.H. Barton, B. Nürnberger, Evolution 57 (2003) 1876–1888."},"article_processing_charge":"No","page":"1876 - 1888","publist_id":"1692","acknowledgement":"We thank G. Mara and T. Galbena for enthusiastic field\r\nassistance, A. Hofmann and R. Sieglstetter for access to their\r\nunpublished data, B. Fo¨rg-Brey and G. Praetzel for help in\r\nthe lab. Helpful comments on a previous version of the man-\r\nuscript were provided by R. Ennos, J. Szymura, F. Balloux,\r\nJ. Bridle, L. Kruuk, F. Bonhomme, M. Arnold, and two anon-\r\nymous reviewers. We also thank A. Pinggera for providing\r\nthe cover illustration. This work was supported by Natural\r\nEnvironment Research Council studentships to THV and TRS\r\nand Deutsche Forschungsgemeinschaft grant Nu 51/2-1 to BN.","publication_identifier":{"issn":["0014-3820"]},"scopus_import":"1","month":"08","volume":57},{"quality_controlled":"1","day":"20","main_file_link":[{"url":"https://doi.org/10.1086/344927","open_access":"1"}],"title":"Probing the reionization history of the universe using the cosmic microwave background polarization","publication_status":"published","publication":"The Astrophysical Journal","abstract":[{"lang":"eng","text":"The recent discovery of a Gunn-Peterson (GP) trough in the spectrum of the redshift 6.28 SDSS quasar has raised the tantalizing possibility that we have detected the reionization of the universe. However, a neutral fraction (of hydrogen) as small as 0.1% is sufficient to cause the GP trough; hence, its detection alone cannot rule out reionization at a much earlier epoch. The cosmic microwave background (CMB) polarization anisotropy offers an alternative way to explore the dark age of the universe. We show that for most models constrained by the current CMB data and by the discovery of a GP trough (showing that reionization occurred at z > 6.3), Microwave Anisotropy Probe (MAP) can detect the reionization signature in the polarization power spectrum. The expected 1 σ error on the measurement of the electron optical depth is around 0.03 with a weak dependence on the value of that optical depth. Such a constraint on the optical depth will allow MAP to achieve a 1 σ error on the amplitude of the primordial power spectrum of 6%. MAP with 2 yr (Planck with 1 yr) of observation can distinguish a model with 50% (6%) partial ionization between redshifts of 6.3 and 20 from a model in which hydrogen was completely neutral at redshifts greater than 6.3. Planck will be able to distinguish between different reionization histories even when they imply the same optical depth to electron scattering for the CMB photons."}],"intvolume":"       583","publication_identifier":{"issn":["0004-637X","1538-4357"]},"volume":583,"month":"01","scopus_import":"1","page":"24-32","citation":{"short":"M. Kaplinghat, M. Chu, Z. Haiman, G.P. Holder, L. Knox, C. Skordis, The Astrophysical Journal 583 (2003) 24–32.","ista":"Kaplinghat M, Chu M, Haiman Z, Holder GP, Knox L, Skordis C. 2003. Probing the reionization history of the universe using the cosmic microwave background polarization. The Astrophysical Journal. 583(1), 24–32.","chicago":"Kaplinghat, Manoj, Mike Chu, Zoltán Haiman, Gilbert P. Holder, Lloyd Knox, and Constantinos Skordis. “Probing the Reionization History of the Universe Using the Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2003. <a href=\"https://doi.org/10.1086/344927\">https://doi.org/10.1086/344927</a>.","ama":"Kaplinghat M, Chu M, Haiman Z, Holder GP, Knox L, Skordis C. Probing the reionization history of the universe using the cosmic microwave background polarization. <i>The Astrophysical Journal</i>. 2003;583(1):24-32. doi:<a href=\"https://doi.org/10.1086/344927\">10.1086/344927</a>","apa":"Kaplinghat, M., Chu, M., Haiman, Z., Holder, G. P., Knox, L., &#38; Skordis, C. (2003). Probing the reionization history of the universe using the cosmic microwave background polarization. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.1086/344927\">https://doi.org/10.1086/344927</a>","mla":"Kaplinghat, Manoj, et al. “Probing the Reionization History of the Universe Using the Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>, vol. 583, no. 1, American Astronomical Society, 2003, pp. 24–32, doi:<a href=\"https://doi.org/10.1086/344927\">10.1086/344927</a>.","ieee":"M. Kaplinghat, M. Chu, Z. Haiman, G. P. Holder, L. Knox, and C. Skordis, “Probing the reionization history of the universe using the cosmic microwave background polarization,” <i>The Astrophysical Journal</i>, vol. 583, no. 1. American Astronomical Society, pp. 24–32, 2003."},"article_processing_charge":"No","author":[{"last_name":"Kaplinghat","first_name":"Manoj","full_name":"Kaplinghat, Manoj"},{"first_name":"Mike","last_name":"Chu","full_name":"Chu, Mike"},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","full_name":"Haiman, Zoltán"},{"full_name":"Holder, Gilbert P.","last_name":"Holder","first_name":"Gilbert P."},{"full_name":"Knox, Lloyd","last_name":"Knox","first_name":"Lloyd"},{"full_name":"Skordis, Constantinos","first_name":"Constantinos","last_name":"Skordis"}],"language":[{"iso":"eng"}],"oa":1,"date_updated":"2024-09-26T14:15:21Z","extern":"1","_id":"17741","oa_version":"Published Version","doi":"10.1086/344927","article_type":"original","type":"journal_article","publisher":"American Astronomical Society","year":"2003","issue":"1","status":"public","date_published":"2003-01-20T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2024-09-06T09:25:08Z"},{"publication":"Monthly Notices of the Royal Astronomical Society","abstract":[{"text":"Recent results by the WMAP satellite suggest that the intergalactic medium was significantly reionized at redshifts as high as z~17. At this early epoch, the first ionizing sources likely appeared in the shallow potential wells of mini-halos with virial temperatures T < 10^4 K. Once such an ionizing source turns off, its surrounding HII region Compton cools and recombines. Nonetheless, we show that the ``fossil'' HII regions left behind remain at high adiabats, prohibiting gas accretion and cooling in subsequent generations of mini-halos. Thus, early star formation is self-limiting. We quantify this effect to show that star formation in mini-halos cannot account for the bulk of the electron scattering opacity measured by WMAP, which must be due to more massive objects. We argue that gas entropy, rather than IGM metallicity, regulates the evolution of the global ionizing emissivity, and impedes full reionization until lower redshifts. We discuss several important consequences of this early entropy floor for reionization. It reduces gas clumping, curtailing the required photon budget for reionization. An entropy floor also prevents H2 formation and cooling, due to reduced gas densities: it greatly enhances feedback from UV photodissociation of H2. An early X-ray background would also furnish an entropy floor to the entire IGM; thus, X-rays impede rather than enhance H2 formation. Future 21cm observations may probe the topology of fossil HII regions.","lang":"eng"}],"intvolume":"       346","publication_status":"published","title":"Fossil H ii regions: Self-limiting star formation at high redshift","day":"01","quality_controlled":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1046/j.1365-2966.2003.07103.x"}],"author":[{"full_name":"Oh, S. Peng","last_name":"Oh","first_name":"S. Peng"},{"first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","last_name":"Haiman","full_name":"Haiman, Zoltán"}],"language":[{"iso":"eng"}],"page":"456-472","citation":{"ieee":"S. P. Oh and Z. Haiman, “Fossil H ii regions: Self-limiting star formation at high redshift,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 346, no. 2. Oxford University Press, pp. 456–472, 2003.","mla":"Oh, S. Peng, and Zoltán Haiman. “Fossil H Ii Regions: Self-Limiting Star Formation at High Redshift.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 346, no. 2, Oxford University Press, 2003, pp. 456–72, doi:<a href=\"https://doi.org/10.1046/j.1365-2966.2003.07103.x\">10.1046/j.1365-2966.2003.07103.x</a>.","ista":"Oh SP, Haiman Z. 2003. Fossil H ii regions: Self-limiting star formation at high redshift. Monthly Notices of the Royal Astronomical Society. 346(2), 456–472.","chicago":"Oh, S. Peng, and Zoltán Haiman. “Fossil H Ii Regions: Self-Limiting Star Formation at High Redshift.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2003. <a href=\"https://doi.org/10.1046/j.1365-2966.2003.07103.x\">https://doi.org/10.1046/j.1365-2966.2003.07103.x</a>.","ama":"Oh SP, Haiman Z. Fossil H ii regions: Self-limiting star formation at high redshift. <i>Monthly Notices of the Royal Astronomical Society</i>. 2003;346(2):456-472. doi:<a href=\"https://doi.org/10.1046/j.1365-2966.2003.07103.x\">10.1046/j.1365-2966.2003.07103.x</a>","apa":"Oh, S. P., &#38; Haiman, Z. (2003). Fossil H ii regions: Self-limiting star formation at high redshift. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1046/j.1365-2966.2003.07103.x\">https://doi.org/10.1046/j.1365-2966.2003.07103.x</a>","short":"S.P. Oh, Z. Haiman, Monthly Notices of the Royal Astronomical Society 346 (2003) 456–472."},"article_processing_charge":"No","oa":1,"publication_identifier":{"issn":["0035-8711"]},"volume":346,"scopus_import":"1","month":"12","oa_version":"Published Version","alternative_title":["Fossil H ii regions"],"_id":"17748","doi":"10.1046/j.1365-2966.2003.07103.x","date_updated":"2024-09-26T15:00:48Z","extern":"1","status":"public","date_published":"2003-12-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2024-09-06T09:36:17Z","article_type":"original","type":"journal_article","publisher":"Oxford University Press","issue":"2","year":"2003"},{"doi":"10.1086/368246","_id":"17750","oa_version":"Published Version","extern":"1","date_updated":"2024-09-30T07:33:02Z","date_created":"2024-09-06T09:38:08Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_published":"2003-04-01T00:00:00Z","status":"public","year":"2003","issue":"4","publisher":"American Astronomical Society","type":"journal_article","article_type":"original","publication_status":"published","title":"A survey of z > 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z > 6","intvolume":"       125","abstract":[{"text":"We present the discovery of three new quasars at z>6 in 1300 deg^2 of SDSS imaging data, J114816.64+525150.3 (z=6.43), J104845.05+463718.3 (z=6.23) and J163033.90+401209.6 (z=6.05). The first two objects have weak Ly alpha emission lines; their redshifts are determined from the positions of the Lyman break. They are only accurate to 0.05 and could be affected by the presence of broad absorption line systems. The last object has a Ly alpha strength more typical of lower redshift quasars. Based on a sample of six quasars at z>5.7 that cover 2870 deg^2 presented in this paper and in Paper I, we estimate the comoving density of luminous quasars at z 6 and M_{1450} < -26.8 to be (8 +/- 3)x10^{-10} Mpc^{-3} (for H_0 = 50 km/s/Mpc, Omega = 1). HST imaging of two z>5.7 quasars and high-resolution ground-based images (seeing 0.4'') of three additional z>5.7 quasars show that none of them is gravitationally lensed. The luminosity distribution of the high-redshfit quasar sample suggests the bright end slope of the quasar luminosity function at z 6 is shallower than Psi L^{-3.5} (2-sigma), consistent with the absence of strongly lensed objects.","lang":"eng"}],"publication":"The Astronomical Journal","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1086/368246"}],"quality_controlled":"1","day":"01","oa":1,"citation":{"chicago":"Fan, Xiaohui, Michael A. Strauss, Donald P. Schneider, Robert H. Becker, Richard L. White, Zoltán Haiman, Michael Gregg, et al. “A Survey of z &#62; 5.7 Quasars in the Sloan Digital Sky Survey. II. Discovery of Three Additional Quasars at z &#62; 6.” <i>The Astronomical Journal</i>. American Astronomical Society, 2003. <a href=\"https://doi.org/10.1086/368246\">https://doi.org/10.1086/368246</a>.","ista":"Fan X, Strauss MA, Schneider DP, Becker RH, White RL, Haiman Z, Gregg M, Pentericci L, Grebel EK, Narayanan VK, Loh Y-S, Richards GT, Gunn JE, Lupton RH, Knapp GR, Ivezić Ž, Brandt WN, Collinge M, Hao L, Harbeck D, Prada F, Schaye J, Strateva I, Zakamska N, Anderson S, Brinkmann J, Bahcall NA, Lamb DQ, Okamura S, Szalay A, York DG. 2003. A survey of z &#62; 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z &#62; 6. The Astronomical Journal. 125(4), 1649–1659.","apa":"Fan, X., Strauss, M. A., Schneider, D. P., Becker, R. H., White, R. L., Haiman, Z., … York, D. G. (2003). A survey of z &#62; 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z &#62; 6. <i>The Astronomical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.1086/368246\">https://doi.org/10.1086/368246</a>","ama":"Fan X, Strauss MA, Schneider DP, et al. A survey of z &#62; 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z &#62; 6. <i>The Astronomical Journal</i>. 2003;125(4):1649-1659. doi:<a href=\"https://doi.org/10.1086/368246\">10.1086/368246</a>","short":"X. Fan, M.A. Strauss, D.P. Schneider, R.H. Becker, R.L. White, Z. Haiman, M. Gregg, L. Pentericci, E.K. Grebel, V.K. Narayanan, Y.-S. Loh, G.T. Richards, J.E. Gunn, R.H. Lupton, G.R. Knapp, Ž. Ivezić, W.N. Brandt, M. Collinge, L. Hao, D. Harbeck, F. Prada, J. Schaye, I. Strateva, N. Zakamska, S. Anderson, J. Brinkmann, N.A. Bahcall, D.Q. Lamb, S. Okamura, A. Szalay, D.G. York, The Astronomical Journal 125 (2003) 1649–1659.","mla":"Fan, Xiaohui, et al. “A Survey of z &#62; 5.7 Quasars in the Sloan Digital Sky Survey. II. Discovery of Three Additional Quasars at z &#62; 6.” <i>The Astronomical Journal</i>, vol. 125, no. 4, American Astronomical Society, 2003, pp. 1649–59, doi:<a href=\"https://doi.org/10.1086/368246\">10.1086/368246</a>.","ieee":"X. Fan <i>et al.</i>, “A survey of z &#62; 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z &#62; 6,” <i>The Astronomical Journal</i>, vol. 125, no. 4. American Astronomical Society, pp. 1649–1659, 2003."},"article_processing_charge":"No","page":"1649-1659","language":[{"iso":"eng"}],"author":[{"last_name":"Fan","first_name":"Xiaohui","full_name":"Fan, Xiaohui"},{"full_name":"Strauss, Michael A.","first_name":"Michael A.","last_name":"Strauss"},{"full_name":"Schneider, Donald P.","last_name":"Schneider","first_name":"Donald P."},{"full_name":"Becker, Robert H.","last_name":"Becker","first_name":"Robert H."},{"full_name":"White, Richard L.","first_name":"Richard L.","last_name":"White"},{"full_name":"Haiman, Zoltán","last_name":"Haiman","first_name":"Zoltán","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36"},{"full_name":"Gregg, Michael","last_name":"Gregg","first_name":"Michael"},{"full_name":"Pentericci, Laura","first_name":"Laura","last_name":"Pentericci"},{"first_name":"Eva K.","last_name":"Grebel","full_name":"Grebel, Eva K."},{"first_name":"Vijay K.","last_name":"Narayanan","full_name":"Narayanan, Vijay K."},{"first_name":"Yeong-Shang","last_name":"Loh","full_name":"Loh, Yeong-Shang"},{"last_name":"Richards","first_name":"Gordon T.","full_name":"Richards, Gordon T."},{"full_name":"Gunn, James E.","first_name":"James E.","last_name":"Gunn"},{"full_name":"Lupton, Robert H.","last_name":"Lupton","first_name":"Robert H."},{"full_name":"Knapp, Gillian R.","first_name":"Gillian R.","last_name":"Knapp"},{"first_name":"Željko","last_name":"Ivezić","full_name":"Ivezić, Željko"},{"full_name":"Brandt, W. N.","first_name":"W. N.","last_name":"Brandt"},{"last_name":"Collinge","first_name":"Matthew","full_name":"Collinge, Matthew"},{"full_name":"Hao, Lei","last_name":"Hao","first_name":"Lei"},{"full_name":"Harbeck, Daniel","last_name":"Harbeck","first_name":"Daniel"},{"full_name":"Prada, Francisco","first_name":"Francisco","last_name":"Prada"},{"last_name":"Schaye","first_name":"Joop","full_name":"Schaye, Joop"},{"first_name":"Iskra","last_name":"Strateva","full_name":"Strateva, Iskra"},{"first_name":"Nadia","last_name":"Zakamska","full_name":"Zakamska, Nadia"},{"full_name":"Anderson, Scott","first_name":"Scott","last_name":"Anderson"},{"last_name":"Brinkmann","first_name":"Jon","full_name":"Brinkmann, Jon"},{"last_name":"Bahcall","first_name":"Neta A.","full_name":"Bahcall, Neta A."},{"first_name":"Don Q.","last_name":"Lamb","full_name":"Lamb, Don Q."},{"full_name":"Okamura, Sadanori","last_name":"Okamura","first_name":"Sadanori"},{"last_name":"Szalay","first_name":"Alex","full_name":"Szalay, Alex"},{"full_name":"York, Donald G.","last_name":"York","first_name":"Donald G."}],"scopus_import":"1","month":"04","volume":125,"publication_identifier":{"issn":["0004-6256","1538-3881"]}},{"oa":1,"language":[{"iso":"eng"}],"author":[{"last_name":"Haiman","id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","full_name":"Haiman, Zoltán"},{"first_name":"Gilbert P.","last_name":"Holder","full_name":"Holder, Gilbert P."}],"article_processing_charge":"No","citation":{"ieee":"Z. Haiman and G. P. Holder, “The reionization history at high redshifts. I. Physical models and new constraints from cosmic microwave background polarization,” <i>The Astrophysical Journal</i>, vol. 595, no. 1. American Astronomical Society, pp. 1–12, 2003.","mla":"Haiman, Zoltán, and Gilbert P. Holder. “The Reionization History at High Redshifts. I. Physical Models and New Constraints from Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>, vol. 595, no. 1, American Astronomical Society, 2003, pp. 1–12, doi:<a href=\"https://doi.org/10.1086/377337\">10.1086/377337</a>.","ista":"Haiman Z, Holder GP. 2003. The reionization history at high redshifts. I. Physical models and new constraints from cosmic microwave background polarization. The Astrophysical Journal. 595(1), 1–12.","chicago":"Haiman, Zoltán, and Gilbert P. Holder. “The Reionization History at High Redshifts. I. Physical Models and New Constraints from Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>. American Astronomical Society, 2003. <a href=\"https://doi.org/10.1086/377337\">https://doi.org/10.1086/377337</a>.","ama":"Haiman Z, Holder GP. The reionization history at high redshifts. I. Physical models and new constraints from cosmic microwave background polarization. <i>The Astrophysical Journal</i>. 2003;595(1):1-12. doi:<a href=\"https://doi.org/10.1086/377337\">10.1086/377337</a>","apa":"Haiman, Z., &#38; Holder, G. P. (2003). The reionization history at high redshifts. I. Physical models and new constraints from cosmic microwave background polarization. <i>The Astrophysical Journal</i>. American Astronomical Society. <a href=\"https://doi.org/10.1086/377337\">https://doi.org/10.1086/377337</a>","short":"Z. Haiman, G.P. Holder, The Astrophysical Journal 595 (2003) 1–12."},"page":"1-12","month":"09","scopus_import":"1","volume":595,"publication_identifier":{"issn":["0004-637X","1538-4357"]},"intvolume":"       595","abstract":[{"lang":"eng","text":"The recent discovery of a high optical depth tau to Thomson scattering from the WMAP data implies that significant reionization took place at redshifts z~15. This discovery has important implications for the sources of reionization, and allows, for the first time, constraints to be placed on physical reionization scenarios out to redshift z~20. Using a new suite of semi-analytic reionization models, we show that the high value of tau requires a surprisingly high efficiency epsilon of the first generation of UV sources for injecting ionizing photons into the intergalactic medium. We find that no simple reionization model can be consistent with the combination of the WMAP result with data from the z<6.5 universe. Satisfying both constraints requires either of the following: (i) H_2 molecules form efficiently at z~20, survive feedback processes, and allow UV sources in halos with virial temperatures below Tvir=10^4 K to contribute substantially to reionization, or (ii) the efficiency epsilon in halos with Tvir>10^4K decreased by a factor of ~ 30 between (z~20) and (z~6). We discuss the relevant physical issues to produce either scenario, and argue that both options are viable, and allowed by current data. In detailed models of the reionization history, we find that the evolution of the ionized fractions in the two scenarios have distinctive features that Planck can distinguish at 3 sigma significance. At the high WMAP value for tau, Planck will also be able to provide tight statistical constraints on reionization model parameters, and elucidate much of the physics at the end of the Dark Ages. The sources responsible for the high optical depth discovered by WMAP should be directly detectable out to z~15 by the James Webb Space Telescope."}],"publication":"The Astrophysical Journal","title":"The reionization history at high redshifts. I. Physical models and new constraints from cosmic microwave background polarization","publication_status":"published","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1086/377337"}],"day":"20","quality_controlled":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_created":"2024-09-06T09:42:24Z","date_published":"2003-09-20T00:00:00Z","status":"public","issue":"1","year":"2003","publisher":"American Astronomical Society","article_type":"original","type":"journal_article","doi":"10.1086/377337","oa_version":"Published Version","_id":"17754","extern":"1","date_updated":"2024-09-30T08:02:54Z"}]