---
OA_place: publisher
OA_type: free access
_id: '3922'
abstract:
- lang: eng
  text: Dispersal is advantageous, but, at the same time, it implies high costs and
    risks. Due to these counteracting selection pressures, many species evolved dispersal
    polymorphisms, which, in ants, are typically restricted to the female sex (queens).
    Male polymorphism is presently only known from a few genera, such as Cardiocondyla,
    in which winged dispersing males coexist with wingless fighter males that mate
    exclusively inside their maternal nests. We studied the developmental mechanisms
    underlying these alternative male morphs and found that, first, male dimorphism
    is not genetically determined, but is induced by environmental conditions (decreasing
    temperature and density). Second, male morph is not yet fixed at the egg stage,
    but it differentiates during larval development. This flexible developmental pattern
    of male morphs allows Cardiocondyla ant colonies to react quickly to changes in
    their environment. Under good conditions, they invest exclusively in philopatric
    wingless males. But, when environmental conditions turn bad, colonies start to
    produce winged dispersal males, even though these males require a many times higher
    investment by the colony than their much smaller wingless counterparts. Cardiocondyla
    ants share this potential of optimal resource allocation with other colonial animals
    and some seed dimorphic plants.
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Jürgen
  full_name: Heinze, Jürgen
  last_name: Heinze
citation:
  ama: 'Cremer S, Heinze J. Stress grows wings: Environmental induction of winged
    dispersal males in Cardiocondyla ants. <i>Current Biology</i>. 2003;13(3):219-223.
    doi:<a href="https://doi.org/10.1016/S0960-9822(03)00012-5">10.1016/S0960-9822(03)00012-5</a>'
  apa: 'Cremer, S., &#38; Heinze, J. (2003). Stress grows wings: Environmental induction
    of winged dispersal males in Cardiocondyla ants. <i>Current Biology</i>. Elsevier.
    <a href="https://doi.org/10.1016/S0960-9822(03)00012-5">https://doi.org/10.1016/S0960-9822(03)00012-5</a>'
  chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental
    Induction of Winged Dispersal Males in Cardiocondyla Ants.” <i>Current Biology</i>.
    Elsevier, 2003. <a href="https://doi.org/10.1016/S0960-9822(03)00012-5">https://doi.org/10.1016/S0960-9822(03)00012-5</a>.'
  ieee: 'S. Cremer and J. Heinze, “Stress grows wings: Environmental induction of
    winged dispersal males in Cardiocondyla ants,” <i>Current Biology</i>, vol. 13,
    no. 3. Elsevier, pp. 219–223, 2003.'
  ista: 'Cremer S, Heinze J. 2003. Stress grows wings: Environmental induction of
    winged dispersal males in Cardiocondyla ants. Current Biology. 13(3), 219–223.'
  mla: 'Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental Induction
    of Winged Dispersal Males in Cardiocondyla Ants.” <i>Current Biology</i>, vol.
    13, no. 3, Elsevier, 2003, pp. 219–23, doi:<a href="https://doi.org/10.1016/S0960-9822(03)00012-5">10.1016/S0960-9822(03)00012-5</a>.'
  short: S. Cremer, J. Heinze, Current Biology 13 (2003) 219–223.
date_created: 2018-12-11T12:05:54Z
date_published: 2003-02-04T00:00:00Z
date_updated: 2026-05-18T09:07:29Z
day: '04'
doi: 10.1016/S0960-9822(03)00012-5
extern: '1'
external_id:
  pmid:
  - '12573217'
fulldoi: https://doi.org/10.1016/S0960-9822(03)00012-5
intvolume: '        13'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/S0960-9822(03)00012-5
month: '02'
oa: 1
oa_version: Published Version
page: 219 - 223
pmid: 1
publication: Current Biology
publication_status: published
publisher: Elsevier
publist_id: '2234'
quality_controlled: '1'
status: public
title: 'Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla
  ants'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2003'
...
---
_id: '3991'
abstract:
- lang: eng
  text: We give analytic inclusion-exclusion formulas for the area and perimeter derivatives
    of a union of finitely many disks in the plane.
acknowledgement: Partially supported by NSF under grant DMS-98-73945 and CCR-00-86013.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ho
  full_name: Cheng, Ho
  last_name: Cheng
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: 'Cheng H, Edelsbrunner H. Area and perimeter derivatives of a union of disks.
    In: <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>.
    Vol 2598. Springer; 2003:88-97. doi:<a href="https://doi.org/10.1007/3-540-36477-3_7">10.1007/3-540-36477-3_7</a>'
  apa: 'Cheng, H., &#38; Edelsbrunner, H. (2003). Area and perimeter derivatives of
    a union of disks. In <i>Computer Science in Perspective: Essays Dedicated to Thomas
    Ottmann</i> (Vol. 2598, pp. 88–97). Springer. <a href="https://doi.org/10.1007/3-540-36477-3_7">https://doi.org/10.1007/3-540-36477-3_7</a>'
  chicago: 'Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of
    a Union of Disks.” In <i>Computer Science in Perspective: Essays Dedicated to
    Thomas Ottmann</i>, 2598:88–97. Springer, 2003. <a href="https://doi.org/10.1007/3-540-36477-3_7">https://doi.org/10.1007/3-540-36477-3_7</a>.'
  ieee: 'H. Cheng and H. Edelsbrunner, “Area and perimeter derivatives of a union
    of disks,” in <i>Computer Science in Perspective: Essays Dedicated to Thomas Ottmann</i>,
    vol. 2598, Springer, 2003, pp. 88–97.'
  ista: 'Cheng H, Edelsbrunner H. 2003.Area and perimeter derivatives of a union of
    disks. In: Computer Science in Perspective: Essays Dedicated to Thomas Ottmann.
    LNCS, vol. 2598, 88–97.'
  mla: 'Cheng, Ho, and Herbert Edelsbrunner. “Area and Perimeter Derivatives of a
    Union of Disks.” <i>Computer Science in Perspective: Essays Dedicated to Thomas
    Ottmann</i>, vol. 2598, Springer, 2003, pp. 88–97, doi:<a href="https://doi.org/10.1007/3-540-36477-3_7">10.1007/3-540-36477-3_7</a>.'
  short: 'H. Cheng, H. Edelsbrunner, in:, Computer Science in Perspective: Essays
    Dedicated to Thomas Ottmann, Springer, 2003, pp. 88–97.'
date_created: 2018-12-11T12:06:18Z
date_published: 2003-02-17T00:00:00Z
date_updated: 2024-02-27T12:15:02Z
day: '17'
doi: 10.1007/3-540-36477-3_7
extern: '1'
fulldoi: https://doi.org/10.1007/3-540-36477-3_7
intvolume: '      2598'
language:
- iso: eng
month: '02'
oa_version: None
page: 88 - 97
publication: 'Computer Science in Perspective: Essays Dedicated to Thomas Ottmann'
publication_identifier:
  isbn:
  - '9783540005797'
publication_status: published
publisher: Springer
publist_id: '2132'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Area and perimeter derivatives of a union of disks
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2598
year: '2003'
...
---
_id: '3992'
abstract:
- lang: eng
  text: Computing the volume occupied by individual atoms in macromolecular structures
    has been the subject of research for several decades. This interest has grown
    in the recent years, because weighted volumes are widely used in implicit solvent
    models. Applications of the latter in molecular mechanics simulations require
    that the derivatives of these weighted volumes be known. In this article, we give
    a formula for the volume derivative of a molecule modeled as a space-filling diagram
    made up of balls in motion. The formula is given in terms of the weights, radii,
    and distances between the centers as well as the sizes of the facets of the power
    diagram restricted to the space-filling diagram. Special attention is given to
    the detection and treatment of singularities as well as discontinuities of the
    derivative.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Patrice
  full_name: Koehl, Patrice
  last_name: Koehl
citation:
  ama: Edelsbrunner H, Koehl P. The weighted-volume derivative of a space-filling
    diagram. <i>PNAS</i>. 2003;100(5):2203-2208. doi:<a href="https://doi.org/10.1073/pnas.0537830100">10.1073/pnas.0537830100</a>
  apa: Edelsbrunner, H., &#38; Koehl, P. (2003). The weighted-volume derivative of
    a space-filling diagram. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.0537830100">https://doi.org/10.1073/pnas.0537830100</a>
  chicago: Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative
    of a Space-Filling Diagram.” <i>PNAS</i>. National Academy of Sciences, 2003.
    <a href="https://doi.org/10.1073/pnas.0537830100">https://doi.org/10.1073/pnas.0537830100</a>.
  ieee: H. Edelsbrunner and P. Koehl, “The weighted-volume derivative of a space-filling
    diagram,” <i>PNAS</i>, vol. 100, no. 5. National Academy of Sciences, pp. 2203–2208,
    2003.
  ista: Edelsbrunner H, Koehl P. 2003. The weighted-volume derivative of a space-filling
    diagram. PNAS. 100(5), 2203–2208.
  mla: Edelsbrunner, Herbert, and Patrice Koehl. “The Weighted-Volume Derivative of
    a Space-Filling Diagram.” <i>PNAS</i>, vol. 100, no. 5, National Academy of Sciences,
    2003, pp. 2203–08, doi:<a href="https://doi.org/10.1073/pnas.0537830100">10.1073/pnas.0537830100</a>.
  short: H. Edelsbrunner, P. Koehl, PNAS 100 (2003) 2203–2208.
date_created: 2018-12-11T12:06:19Z
date_published: 2003-03-04T00:00:00Z
date_updated: 2024-02-27T12:31:59Z
day: '04'
doi: 10.1073/pnas.0537830100
extern: '1'
external_id:
  pmid:
  - '12601153'
fulldoi: https://doi.org/10.1073/pnas.0537830100
intvolume: '       100'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151318/
month: '03'
oa: 1
oa_version: Published Version
page: 2203 - 2208
pmid: 1
publication: PNAS
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2133'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The weighted-volume derivative of a space-filling diagram
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 100
year: '2003'
...
---
OA_type: closed access
_id: '3993'
abstract:
- lang: eng
  text: We present algorithms for constructing a hierarchy of increasingly coarse
    Morse-Smale complexes that decompose a piecewise linear 2-manifold. While these
    complexes are defined only in the smooth category, we extend the construction
    to the piecewise linearcategory by ensuring structural integrity and simulating
    differentiability. We then simplify Morse-Smale complexes by canceling pairs of
    critical points in order of increasing persistence.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: John
  full_name: Harer, John
  last_name: Harer
- first_name: Afra
  full_name: Zomorodian, Afra
  last_name: Zomorodian
citation:
  ama: Edelsbrunner H, Harer J, Zomorodian A. Hierarchical Morse-Smale complexes for
    piecewise linear 2-manifolds. <i>Discrete &#38; Computational Geometry</i>. 2003;30:87-107.
    doi:<a href="https://doi.org/10.1007/s00454-003-2926-5">10.1007/s00454-003-2926-5</a>
  apa: Edelsbrunner, H., Harer, J., &#38; Zomorodian, A. (2003). Hierarchical Morse-Smale
    complexes for piecewise linear 2-manifolds. <i>Discrete &#38; Computational Geometry</i>.
    Springer nature. <a href="https://doi.org/10.1007/s00454-003-2926-5">https://doi.org/10.1007/s00454-003-2926-5</a>
  chicago: Edelsbrunner, Herbert, John Harer, and Afra Zomorodian. “Hierarchical Morse-Smale
    Complexes for Piecewise Linear 2-Manifolds.” <i>Discrete &#38; Computational Geometry</i>.
    Springer nature, 2003. <a href="https://doi.org/10.1007/s00454-003-2926-5">https://doi.org/10.1007/s00454-003-2926-5</a>.
  ieee: H. Edelsbrunner, J. Harer, and A. Zomorodian, “Hierarchical Morse-Smale complexes
    for piecewise linear 2-manifolds,” <i>Discrete &#38; Computational Geometry</i>,
    vol. 30. Springer nature, pp. 87–107, 2003.
  ista: Edelsbrunner H, Harer J, Zomorodian A. 2003. Hierarchical Morse-Smale complexes
    for piecewise linear 2-manifolds. Discrete &#38; Computational Geometry. 30, 87–107.
  mla: Edelsbrunner, Herbert, et al. “Hierarchical Morse-Smale Complexes for Piecewise
    Linear 2-Manifolds.” <i>Discrete &#38; Computational Geometry</i>, vol. 30, Springer
    nature, 2003, pp. 87–107, doi:<a href="https://doi.org/10.1007/s00454-003-2926-5">10.1007/s00454-003-2926-5</a>.
  short: H. Edelsbrunner, J. Harer, A. Zomorodian, Discrete &#38; Computational Geometry
    30 (2003) 87–107.
date_created: 2018-12-11T12:06:19Z
date_published: 2003-05-01T00:00:00Z
date_updated: 2026-05-06T08:08:23Z
day: '01'
doi: 10.1007/s00454-003-2926-5
extern: '1'
fulldoi: https://doi.org/10.1007/s00454-003-2926-5
intvolume: '        30'
language:
- iso: eng
month: '05'
oa_version: None
page: 87 - 107
publication: Discrete & Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issnl:
  - 0179-5376
publication_status: published
publisher: Springer nature
publist_id: '2134'
quality_controlled: '1'
status: public
title: Hierarchical Morse-Smale complexes for piecewise linear 2-manifolds
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 30
year: '2003'
...
---
OA_type: closed access
_id: '3994'
abstract:
- lang: eng
  text: The body defined by a finite collection of disks is a subset of the plane
    bounded by a tangent continuous curve, which we call the skin. We give analytic
    formulas for the area, the perimeter, the area derivative, and the perimeter derivative
    of the body. Given the filtrations of the Delaunay triangulation and the Voronoi
    diagram of the disks, all formulas can be evaluated in time proportional to the
    number of disks.
article_processing_charge: No
article_type: original
author:
- first_name: Ho
  full_name: Cheng, Ho
  last_name: Cheng
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: Cheng H, Edelsbrunner H. Area, perimeter and derivatives of a skin curve. <i>Computational
    Geometry</i>. 2003;26(2):173-192. doi:<a href="https://doi.org/10.1016/S0925-7721(02)00124-4">10.1016/S0925-7721(02)00124-4</a>
  apa: Cheng, H., &#38; Edelsbrunner, H. (2003). Area, perimeter and derivatives of
    a skin curve. <i>Computational Geometry</i>. Elsevier. <a href="https://doi.org/10.1016/S0925-7721(02)00124-4">https://doi.org/10.1016/S0925-7721(02)00124-4</a>
  chicago: Cheng, Ho, and Herbert Edelsbrunner. “Area, Perimeter and Derivatives of
    a Skin Curve.” <i>Computational Geometry</i>. Elsevier, 2003. <a href="https://doi.org/10.1016/S0925-7721(02)00124-4">https://doi.org/10.1016/S0925-7721(02)00124-4</a>.
  ieee: H. Cheng and H. Edelsbrunner, “Area, perimeter and derivatives of a skin curve,”
    <i>Computational Geometry</i>, vol. 26, no. 2. Elsevier, pp. 173–192, 2003.
  ista: Cheng H, Edelsbrunner H. 2003. Area, perimeter and derivatives of a skin curve.
    Computational Geometry. 26(2), 173–192.
  mla: Cheng, Ho, and Herbert Edelsbrunner. “Area, Perimeter and Derivatives of a
    Skin Curve.” <i>Computational Geometry</i>, vol. 26, no. 2, Elsevier, 2003, pp.
    173–92, doi:<a href="https://doi.org/10.1016/S0925-7721(02)00124-4">10.1016/S0925-7721(02)00124-4</a>.
  short: H. Cheng, H. Edelsbrunner, Computational Geometry 26 (2003) 173–192.
date_created: 2018-12-11T12:06:20Z
date_published: 2003-10-01T00:00:00Z
date_updated: 2026-05-06T08:12:09Z
day: '01'
doi: 10.1016/S0925-7721(02)00124-4
extern: '1'
fulldoi: https://doi.org/10.1016/S0925-7721(02)00124-4
intvolume: '        26'
issue: '2'
keyword:
- Computational geometry
- Differential geometry
- Skin curves
- Voronoi diagrams
- Delaunay triangulations
- Filtrations
- Disks
- Hyperbolas
- Area
- Perimeter
- Derivatives
language:
- iso: eng
month: '10'
oa_version: None
page: 173 - 192
publication: Computational Geometry
publication_status: published
publisher: Elsevier
publist_id: '2135'
quality_controlled: '1'
status: public
title: Area, perimeter and derivatives of a skin curve
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 26
year: '2003'
...
---
_id: '3997'
abstract:
- lang: eng
  text: We combine topological and geometric methods to construct a multi-resolution
    data structure for functions over two-dimensional domains. Starting with the Morse-Smale
    complex, we construct a topological hierarchy by progressively canceling critical
    points in pairs. Concurrently, we create a geometric hierarchy by adapting the
    geometry to the changes in topology. The data structure supports mesh traversal
    operations similarly to traditional multi-resolution representations.
acknowledgement: This work was performed under the auspices of the U. S. Department
  of Energy by University of California Lawrence Livermore National Laboratory under
  contract No. W-7405-Eng-48. H. Edelsbrunner is partially supported by the National
  Science Foundation (NFS) under grants EIA-99-72879 and CCR-00-86013. B. Hamann is
  supported by the NSF under contract ACI 9624034, through the LSSDSV program under
  contract ACI 9982251, and through the NPACI; the National Institute of Mental Health
  and the NSF under contract NIMH 2 P20 MH60975-06A2; the Lawrence Livermore National
  Laboratory under ASCI ASAP Level-2 Memorandum Agreement B347878 and under Memorandum
  Agreement B503159.
article_processing_charge: No
author:
- first_name: Peer
  full_name: Bremer, Peer
  last_name: Bremer
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Bernd
  full_name: Hamann, Bernd
  last_name: Hamann
- first_name: Valerio
  full_name: Pascucci, Valerio
  last_name: Pascucci
citation:
  ama: 'Bremer P, Edelsbrunner H, Hamann B, Pascucci V. A multi-resolution data structure
    for two-dimensional Morse-Smale functions. In: <i>Proceedings of the 14th IEEE
    Conference on Visualization </i>. IEEE; 2003:139-146. doi:<a href="https://doi.org/10.1109/VISUAL.2003.1250365">10.1109/VISUAL.2003.1250365</a>'
  apa: 'Bremer, P., Edelsbrunner, H., Hamann, B., &#38; Pascucci, V. (2003). A multi-resolution
    data structure for two-dimensional Morse-Smale functions. In <i>Proceedings of
    the 14th IEEE Conference on Visualization </i> (pp. 139–146). Seattle, WA, USA
    : IEEE. <a href="https://doi.org/10.1109/VISUAL.2003.1250365">https://doi.org/10.1109/VISUAL.2003.1250365</a>'
  chicago: Bremer, Peer, Herbert Edelsbrunner, Bernd Hamann, and Valerio Pascucci.
    “A Multi-Resolution Data Structure for Two-Dimensional Morse-Smale Functions.”
    In <i>Proceedings of the 14th IEEE Conference on Visualization </i>, 139–46. IEEE,
    2003. <a href="https://doi.org/10.1109/VISUAL.2003.1250365">https://doi.org/10.1109/VISUAL.2003.1250365</a>.
  ieee: P. Bremer, H. Edelsbrunner, B. Hamann, and V. Pascucci, “A multi-resolution
    data structure for two-dimensional Morse-Smale functions,” in <i>Proceedings of
    the 14th IEEE Conference on Visualization </i>, Seattle, WA, USA , 2003, pp. 139–146.
  ista: 'Bremer P, Edelsbrunner H, Hamann B, Pascucci V. 2003. A multi-resolution
    data structure for two-dimensional Morse-Smale functions. Proceedings of the 14th
    IEEE Conference on Visualization . VIS: IEEE Visualization, 139–146.'
  mla: Bremer, Peer, et al. “A Multi-Resolution Data Structure for Two-Dimensional
    Morse-Smale Functions.” <i>Proceedings of the 14th IEEE Conference on Visualization
    </i>, IEEE, 2003, pp. 139–46, doi:<a href="https://doi.org/10.1109/VISUAL.2003.1250365">10.1109/VISUAL.2003.1250365</a>.
  short: P. Bremer, H. Edelsbrunner, B. Hamann, V. Pascucci, in:, Proceedings of the
    14th IEEE Conference on Visualization , IEEE, 2003, pp. 139–146.
conference:
  end_date: 2003-10-24
  location: 'Seattle, WA, USA '
  name: 'VIS: IEEE Visualization'
  start_date: 2003-10-19
date_created: 2018-12-11T12:06:21Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-02-27T11:12:50Z
day: '01'
doi: 10.1109/VISUAL.2003.1250365
extern: '1'
fulldoi: https://doi.org/10.1109/VISUAL.2003.1250365
language:
- iso: eng
month: '08'
oa_version: None
page: 139 - 146
publication: 'Proceedings of the 14th IEEE Conference on Visualization '
publication_identifier:
  isbn:
  - '0780381203'
publication_status: published
publisher: IEEE
publist_id: '2131'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A multi-resolution data structure for two-dimensional Morse-Smale functions
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2003'
...
---
_id: '3999'
abstract:
- lang: eng
  text: We introduce relaxed scheduling as a paradigm for mesh maintenance and demonstrate
    its applicability to triangulating a skin surface in R-3.
acknowledgement: NSF under grant CCR-00- 86013.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Alper
  full_name: Üngör, Alper
  last_name: Üngör
citation:
  ama: 'Edelsbrunner H, Üngör A. Relaxed scheduling in dynamic skin triangulation.
    In: <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry
    </i>. Vol 2866. Springer; 2003:135-151. doi:<a href="https://doi.org/10.1007/978-3-540-44400-8_14">10.1007/978-3-540-44400-8_14</a>'
  apa: 'Edelsbrunner, H., &#38; Üngör, A. (2003). Relaxed scheduling in dynamic skin
    triangulation. In <i>Proceedings of the Japanese Conference on Discrete and Computational
    Geometry </i> (Vol. 2866, pp. 135–151). Tokyo, Japan: Springer. <a href="https://doi.org/10.1007/978-3-540-44400-8_14">https://doi.org/10.1007/978-3-540-44400-8_14</a>'
  chicago: Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic
    Skin Triangulation.” In <i>Proceedings of the Japanese Conference on Discrete
    and Computational Geometry </i>, 2866:135–51. Springer, 2003. <a href="https://doi.org/10.1007/978-3-540-44400-8_14">https://doi.org/10.1007/978-3-540-44400-8_14</a>.
  ieee: H. Edelsbrunner and A. Üngör, “Relaxed scheduling in dynamic skin triangulation,”
    in <i>Proceedings of the Japanese Conference on Discrete and Computational Geometry
    </i>, Tokyo, Japan, 2003, vol. 2866, pp. 135–151.
  ista: 'Edelsbrunner H, Üngör A. 2003. Relaxed scheduling in dynamic skin triangulation.
    Proceedings of the Japanese Conference on Discrete and Computational Geometry
    . JCDCG: Japanese Conference on Discrete and Computational Geometry, LNCS, vol.
    2866, 135–151.'
  mla: Edelsbrunner, Herbert, and Alper Üngör. “Relaxed Scheduling in Dynamic Skin
    Triangulation.” <i>Proceedings of the Japanese Conference on Discrete and Computational
    Geometry </i>, vol. 2866, Springer, 2003, pp. 135–51, doi:<a href="https://doi.org/10.1007/978-3-540-44400-8_14">10.1007/978-3-540-44400-8_14</a>.
  short: H. Edelsbrunner, A. Üngör, in:, Proceedings of the Japanese Conference on
    Discrete and Computational Geometry , Springer, 2003, pp. 135–151.
conference:
  end_date: 2002-12-09
  location: Tokyo, Japan
  name: 'JCDCG: Japanese Conference on Discrete and Computational Geometry'
  start_date: 2002-12-06
date_created: 2018-12-11T12:06:21Z
date_published: 2003-12-16T00:00:00Z
date_updated: 2024-02-27T11:07:15Z
day: '16'
doi: 10.1007/978-3-540-44400-8_14
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-540-44400-8_14
intvolume: '      2866'
language:
- iso: eng
month: '12'
oa_version: None
page: 135 - 151
publication: 'Proceedings of the Japanese Conference on Discrete and Computational
  Geometry '
publication_identifier:
  isbn:
  - '9783540207764'
publication_status: published
publisher: Springer
publist_id: '2127'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Relaxed scheduling in dynamic skin triangulation
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2866
year: '2003'
...
---
_id: '4146'
abstract:
- lang: eng
  text: During vertebrate gastrulation, highly coordinated cellular rearrangements
    lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm.
    In zebrafish, silberblick (slb)/wnt11 regulates normal gastrulation movements
    by activating a signalling pathway similar to the Frizzled-signalling pathway,
    which establishes epithelial planar cell polarity (PCP) in Drosophila. However,
    the cellular mechanisms by which slb/wnt11 functions during zebrafish gastrulation
    are still unclear. Using high-resolution two-photon confocal imaging followed
    by computer-assisted reconstruction and motion analysis, we have analysed the
    movement and morphology of individual cells in three dimensions during the course
    of gastrulation. We show that in slb-mutant embryos, hypoblast cells within the
    forming germ ring have slower, less directed migratory movements at the onset
    of gastrulation. These aberrant cell movements are accompanied by defects in the
    orientation of cellular processes along the individual movement directions of
    these cells. We conclude that slb/wnt11-mediated orientation of cellular processes
    plays a role in facilitating and stabilising movements of hypoblast cells in the
    germ ring, thereby pointing at a novel function of the slb/wnt11 signalling pathway
    for the regulation of migratory cell movements at early stages of gastrulation.
acknowledgement: 'We thank Jennifer Geiger, Mathias Köppen, Christian Dahmann and
  Marcos Gonzalez-Gaitan for helpful comments on earlier versions of this manuscript,Beate
  Kilian for technical assistance, Ugur Yalcin, Katrin Anczok and Viktor Schnabel
  for help with the image analysis, Vinzenz Link for programming Excel Macros and
  Harald Brush-Janovjak for extensive reviews of the statistics part of this work.
  We are grateful to Kurt Anderson and Jan Peychl for help with the confocal microscopy.
  P.J.H., E.V. and D.R.S. are supported by NIH grant HD-18577, The W.M Keck Foundation
  and the Developmental Studies Hybridoma Bank(DSHB), P.J.H. by The American Cancer
  Society (grant # PF-01-110-01-CSM),M.L.C. and S.W.W. by the Wellcome Trust, M.T.
  by an MRC Career Development Award, and F.U. and C.P.H. by an Emmy-Noether-Fellowship
  from the DFG.'
article_processing_charge: No
article_type: original
author:
- first_name: Florian
  full_name: Ulrich, Florian
  last_name: Ulrich
- first_name: Miguel
  full_name: Concha, Miguel
  last_name: Concha
- first_name: Paul
  full_name: Heid, Paul
  last_name: Heid
- first_name: Ed
  full_name: Voss, Ed
  last_name: Voss
- first_name: Sabine
  full_name: Witzel, Sabine
  last_name: Witzel
- first_name: Henry
  full_name: Roehl, Henry
  last_name: Roehl
- first_name: Masazumi
  full_name: Tada, Masazumi
  last_name: Tada
- first_name: Stephen
  full_name: Wilson, Stephen
  last_name: Wilson
- first_name: Richard
  full_name: Adams, Richard
  last_name: Adams
- first_name: David
  full_name: Soll, David
  last_name: Soll
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Ulrich F, Concha M, Heid P, et al. Slb/Wnt11 controls hypoblast cell migration
    and morphogenesis at the onset of zebrafish gastrulation. <i>Development</i>.
    2003;130(22):5375-5384. doi:<a href="https://doi.org/10.1242/dev.00758">10.1242/dev.00758</a>
  apa: Ulrich, F., Concha, M., Heid, P., Voss, E., Witzel, S., Roehl, H., … Heisenberg,
    C.-P. J. (2003). Slb/Wnt11 controls hypoblast cell migration and morphogenesis
    at the onset of zebrafish gastrulation. <i>Development</i>. Company of Biologists.
    <a href="https://doi.org/10.1242/dev.00758">https://doi.org/10.1242/dev.00758</a>
  chicago: Ulrich, Florian, Miguel Concha, Paul Heid, Ed Voss, Sabine Witzel, Henry
    Roehl, Masazumi Tada, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and
    Morphogenesis at the Onset of Zebrafish Gastrulation.” <i>Development</i>. Company
    of Biologists, 2003. <a href="https://doi.org/10.1242/dev.00758">https://doi.org/10.1242/dev.00758</a>.
  ieee: F. Ulrich <i>et al.</i>, “Slb/Wnt11 controls hypoblast cell migration and
    morphogenesis at the onset of zebrafish gastrulation,” <i>Development</i>, vol.
    130, no. 22. Company of Biologists, pp. 5375–5384, 2003.
  ista: Ulrich F, Concha M, Heid P, Voss E, Witzel S, Roehl H, Tada M, Wilson S, Adams
    R, Soll D, Heisenberg C-PJ. 2003. Slb/Wnt11 controls hypoblast cell migration
    and morphogenesis at the onset of zebrafish gastrulation. Development. 130(22),
    5375–5384.
  mla: Ulrich, Florian, et al. “Slb/Wnt11 Controls Hypoblast Cell Migration and Morphogenesis
    at the Onset of Zebrafish Gastrulation.” <i>Development</i>, vol. 130, no. 22,
    Company of Biologists, 2003, pp. 5375–84, doi:<a href="https://doi.org/10.1242/dev.00758">10.1242/dev.00758</a>.
  short: F. Ulrich, M. Concha, P. Heid, E. Voss, S. Witzel, H. Roehl, M. Tada, S.
    Wilson, R. Adams, D. Soll, C.-P.J. Heisenberg, Development 130 (2003) 5375–5384.
date_created: 2018-12-11T12:07:13Z
date_published: 2003-11-15T00:00:00Z
date_updated: 2024-02-27T10:14:21Z
day: '15'
doi: 10.1242/dev.00758
extern: '1'
external_id:
  pmid:
  - ' PMC1414802'
fulldoi: https://doi.org/10.1242/dev.00758
intvolume: '       130'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414802/
month: '11'
oa: 1
oa_version: None
page: 5375 - 5384
pmid: 1
publication: Development
publication_identifier:
  issn:
  - 1011-6370
publication_status: published
publisher: Company of Biologists
publist_id: '1975'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset
  of zebrafish gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 130
year: '2003'
...
---
_id: '4168'
abstract:
- lang: eng
  text: Recent studies show that signaling through integrin receptors is required
    for normal cell movements during Xenopus gastrulation. Integrins function in this
    process by modulating the activity of cadherin adhesion molecules within tissues
    undergoing convergence and extension movements.
article_processing_charge: No
article_type: original
author:
- first_name: Juan
  full_name: Montero, Juan
  last_name: Montero
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Montero J, Heisenberg C-PJ. Adhesive crosstalk in gastrulation. <i>Developmental
    Cell</i>. 2003;5(2):190-191. doi:<a href="https://doi.org/10.1016/S1534-5807(03)00235-1">10.1016/S1534-5807(03)00235-1</a>
  apa: Montero, J., &#38; Heisenberg, C.-P. J. (2003). Adhesive crosstalk in gastrulation.
    <i>Developmental Cell</i>. Cell Press. <a href="https://doi.org/10.1016/S1534-5807(03)00235-1">https://doi.org/10.1016/S1534-5807(03)00235-1</a>
  chicago: Montero, Juan, and Carl-Philipp J Heisenberg. “Adhesive Crosstalk in Gastrulation.”
    <i>Developmental Cell</i>. Cell Press, 2003. <a href="https://doi.org/10.1016/S1534-5807(03)00235-1">https://doi.org/10.1016/S1534-5807(03)00235-1</a>.
  ieee: J. Montero and C.-P. J. Heisenberg, “Adhesive crosstalk in gastrulation,”
    <i>Developmental Cell</i>, vol. 5, no. 2. Cell Press, pp. 190–191, 2003.
  ista: Montero J, Heisenberg C-PJ. 2003. Adhesive crosstalk in gastrulation. Developmental
    Cell. 5(2), 190–191.
  mla: Montero, Juan, and Carl-Philipp J. Heisenberg. “Adhesive Crosstalk in Gastrulation.”
    <i>Developmental Cell</i>, vol. 5, no. 2, Cell Press, 2003, pp. 190–91, doi:<a
    href="https://doi.org/10.1016/S1534-5807(03)00235-1">10.1016/S1534-5807(03)00235-1</a>.
  short: J. Montero, C.-P.J. Heisenberg, Developmental Cell 5 (2003) 190–191.
date_created: 2018-12-11T12:07:21Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-02-27T09:54:53Z
day: '01'
doi: 10.1016/S1534-5807(03)00235-1
extern: '1'
external_id:
  pmid:
  - '12919669 '
fulldoi: https://doi.org/10.1016/S1534-5807(03)00235-1
intvolume: '         5'
issue: '2'
language:
- iso: eng
month: '08'
oa_version: None
page: 190 - 191
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - 1878-1551
  issn:
  - 1534-5807
publication_status: published
publisher: Cell Press
publist_id: '1949'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adhesive crosstalk in gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 5
year: '2003'
...
---
_id: '4169'
abstract:
- lang: eng
  text: 'Background: During vertebrate gastrulation, cell polarization and migration
    are core components in the cellular rearrangements that lead to the formation
    of the three germ layers, ectoderm, mesoderm, and endoderm. Previous studies have
    implicated the Wnt/planar cell polarity (PCP) signaling pathway in controlling
    cell morphology and movement during gastrulation. However, cell polarization and
    directed cell migration are reduced but not completely abolished in the absence
    of Wnt/PCP signals; this observation indicates that other signaling pathways must
    be involved. Results: We show that Phosphoinositide 3-Kinases (PI3Ks) are required
    at the onset of zebrafish gastrulation in mesendodermal cells for process formation
    and cell polarization. Platelet Derived Growth Factor (PDGF) functions upstream
    of PI3K, while Protein Kinase B (PKB), a downstream effector of PI3K activity,
    localizes to the leading edge of migrating mesendodermal cells. In the absence
    of PI3K activity, PKB localization and cell polarization are strongly reduced
    in mesendodermal cells and are followed by slower but still highly coordinated
    and directed movements of these cells. Conclusions: We have identified a novel
    role of a signaling pathway comprised of PDGF, PI3K, and PKB in the control of
    morphogenetic cell movements during gastrulation. Furthermore, our findings provide
    insight into the relationship between cell polarization and directed cell migration
    at the onset of zebrafish gastrulation.'
acknowledgement: 'We would like to thank Jennifer Geiger, Juan Hurl& Hannu Mansu-koski,
  Florian Raible, Marino Zerial, Steve Wilson, and Kurt Anderson for critical reading
  of earlier versions of this manuscript. We thank Erez Raz, Bart Vanhaesebroeck,
  and Lukas Roth for sending us the pCS2-PH-GFP-nos, the p1IOCAAX, and the pCS2-actin-GFP
  constructs, respectively. We are grateful to Marino Zerial and his lab for encouraging
  us to start this work and providing us with the dnP13K construct and to Florian
  Ulrich and Franziska Friedrich for help with the confocal microscope and artwork,
  respectively. We thank Gunter Junghanns and Evelyn Lehmann for excellent fish care.
  C.-P.H. is supported by an Emmy-Noother-Fellowship from the Deutsche Forschungsgemeinschaft. '
article_processing_charge: No
article_type: original
author:
- first_name: Juan
  full_name: Montero, Juan
  last_name: Montero
- first_name: Beate
  full_name: Kilian, Beate
  last_name: Kilian
- first_name: Joanne
  full_name: Chan, Joanne
  last_name: Chan
- first_name: Peter
  full_name: Bayliss, Peter
  last_name: Bayliss
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. Phosphoinositide 3-kinase
    is required for process outgrowth and cell polarization of gastrulating mesendodermal
    cells. <i>Current Biology</i>. 2003;13(15):1279-1289. doi:<a href="https://doi.org/10.1016/S0960-9822(03)00505-0">10.1016/S0960-9822(03)00505-0</a>
  apa: Montero, J., Kilian, B., Chan, J., Bayliss, P., &#38; Heisenberg, C.-P. J.
    (2003). Phosphoinositide 3-kinase is required for process outgrowth and cell polarization
    of gastrulating mesendodermal cells. <i>Current Biology</i>. Cell Press. <a href="https://doi.org/10.1016/S0960-9822(03)00505-0">https://doi.org/10.1016/S0960-9822(03)00505-0</a>
  chicago: Montero, Juan, Beate Kilian, Joanne Chan, Peter Bayliss, and Carl-Philipp
    J Heisenberg. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth and
    Cell Polarization of Gastrulating Mesendodermal Cells.” <i>Current Biology</i>.
    Cell Press, 2003. <a href="https://doi.org/10.1016/S0960-9822(03)00505-0">https://doi.org/10.1016/S0960-9822(03)00505-0</a>.
  ieee: J. Montero, B. Kilian, J. Chan, P. Bayliss, and C.-P. J. Heisenberg, “Phosphoinositide
    3-kinase is required for process outgrowth and cell polarization of gastrulating
    mesendodermal cells,” <i>Current Biology</i>, vol. 13, no. 15. Cell Press, pp.
    1279–1289, 2003.
  ista: Montero J, Kilian B, Chan J, Bayliss P, Heisenberg C-PJ. 2003. Phosphoinositide
    3-kinase is required for process outgrowth and cell polarization of gastrulating
    mesendodermal cells. Current Biology. 13(15), 1279–1289.
  mla: Montero, Juan, et al. “Phosphoinositide 3-Kinase Is Required for Process Outgrowth
    and Cell Polarization of Gastrulating Mesendodermal Cells.” <i>Current Biology</i>,
    vol. 13, no. 15, Cell Press, 2003, pp. 1279–89, doi:<a href="https://doi.org/10.1016/S0960-9822(03)00505-0">10.1016/S0960-9822(03)00505-0</a>.
  short: J. Montero, B. Kilian, J. Chan, P. Bayliss, C.-P.J. Heisenberg, Current Biology
    13 (2003) 1279–1289.
date_created: 2018-12-11T12:07:22Z
date_published: 2003-08-05T00:00:00Z
date_updated: 2024-02-27T10:03:37Z
day: '05'
doi: 10.1016/S0960-9822(03)00505-0
extern: '1'
external_id:
  pmid:
  - ' 12906787'
fulldoi: https://doi.org/10.1016/S0960-9822(03)00505-0
intvolume: '        13'
issue: '15'
language:
- iso: eng
month: '08'
oa_version: None
page: 1279 - 1289
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1950'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phosphoinositide 3-kinase is required for process outgrowth and cell polarization
  of gastrulating mesendodermal cells
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2003'
...
---
_id: '4185'
abstract:
- lang: eng
  text: Wnt genes play important roles in regulating patterning and morphogenesis
    during vertebrate gastrulation. In zebrafish, slb/wnt11 is required for convergence
    and extension movements, but not cell fate specification during gastrulation.
    To determine if other Wnt genes functionally interact with slb/wnt11, we analysed
    the role of ppt/wnt5 during zebrafish gastrulation. ppt/wnt5 is maternally provided
    and zygotically expressed at all stages during gastrulation. The analysis of ppt
    mutant embryos reveals that Ppt/Wnt5 regulates cell elongation and convergent
    extension movements in posterior regions of the gastrula, while its function in
    more anterior regions is largely redundant to that of Slb/Wnt11. Frizzled-2 functions
    downstream of ppt/wnt5, indicating that it might act as a receptor for Ppt/Wnt5
    in this process. The characterisation of the role of Ppt/Wnt5 provides insight
    into the functional diversity of Wnt genes in regulating vertebrate gastrulation
    movements. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
acknowledgement: We thank Michael Brand, Florian Raible, Gerlinde Reim, Tobias Langenberg,
  Jennifer Geiger and Kate Poole for helpful comments on earlier versions of this
  manuscript. We are grateful to Henry Roehl and Christiane Nüsslein Volhard for sending
  us the ppt mutant stock. M.T. was supported by a Career Development Fellowship from
  the MRC. B.K., H.M. and C.P.H. are supported by an Emmy Noether-Fellowship from
  the DFG.
article_processing_charge: No
article_type: original
author:
- first_name: Beate
  full_name: Kilian, Beate
  last_name: Kilian
- first_name: Hannu
  full_name: Mansukoski, Hannu
  last_name: Mansukoski
- first_name: Filipa
  full_name: Barbosa, Filipa
  last_name: Barbosa
- first_name: Florian
  full_name: Ulrich, Florian
  last_name: Ulrich
- first_name: Masazumi
  full_name: Tada, Masazumi
  last_name: Tada
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. The role
    of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation.
    <i>Mechanisms of Development</i>. 2003;120(4):467-476. doi:<a href="https://doi.org/10.1016/S0925-4773(03)00004-2">10.1016/S0925-4773(03)00004-2</a>
  apa: Kilian, B., Mansukoski, H., Barbosa, F., Ulrich, F., Tada, M., &#38; Heisenberg,
    C.-P. J. (2003). The role of Ppt/Wnt5 in regulating cell shape and movement during
    zebrafish gastrulation. <i>Mechanisms of Development</i>. Elsevier. <a href="https://doi.org/10.1016/S0925-4773(03)00004-2">https://doi.org/10.1016/S0925-4773(03)00004-2</a>
  chicago: Kilian, Beate, Hannu Mansukoski, Filipa Barbosa, Florian Ulrich, Masazumi
    Tada, and Carl-Philipp J Heisenberg. “The Role of Ppt/Wnt5 in Regulating Cell
    Shape and Movement during Zebrafish Gastrulation.” <i>Mechanisms of Development</i>.
    Elsevier, 2003. <a href="https://doi.org/10.1016/S0925-4773(03)00004-2">https://doi.org/10.1016/S0925-4773(03)00004-2</a>.
  ieee: B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, and C.-P. J. Heisenberg,
    “The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation,”
    <i>Mechanisms of Development</i>, vol. 120, no. 4. Elsevier, pp. 467–476, 2003.
  ista: Kilian B, Mansukoski H, Barbosa F, Ulrich F, Tada M, Heisenberg C-PJ. 2003.
    The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation.
    Mechanisms of Development. 120(4), 467–476.
  mla: Kilian, Beate, et al. “The Role of Ppt/Wnt5 in Regulating Cell Shape and Movement
    during Zebrafish Gastrulation.” <i>Mechanisms of Development</i>, vol. 120, no.
    4, Elsevier, 2003, pp. 467–76, doi:<a href="https://doi.org/10.1016/S0925-4773(03)00004-2">10.1016/S0925-4773(03)00004-2</a>.
  short: B. Kilian, H. Mansukoski, F. Barbosa, F. Ulrich, M. Tada, C.-P.J. Heisenberg,
    Mechanisms of Development 120 (2003) 467–476.
date_created: 2018-12-11T12:07:27Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2024-02-27T09:46:39Z
day: '01'
doi: 10.1016/S0925-4773(03)00004-2
extern: '1'
external_id:
  pmid:
  - '12676324 '
fulldoi: https://doi.org/10.1016/S0925-4773(03)00004-2
intvolume: '       120'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 467 - 476
pmid: 1
publication: Mechanisms of Development
publication_identifier:
  issn:
  - 0925-4773
publication_status: published
publisher: Elsevier
publist_id: '1934'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish
  gastrulation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 120
year: '2003'
...
---
_id: '4254'
abstract:
- lang: eng
  text: Chromosomal rearrangements can promote reproductive isolation by reducing
    recombination along a large section of the genome. We model the effects of the
    genetic barrier to gene flow caused by a chromosomal rearrangement on the rate
    of accumulation of postzygotic isolation genes in parapatry. We find that, if
    reproductive isolation is produced by the accumulation in parapatry of sets of
    alleles compatible within but incompatible across species, chromosomal rearrangements
    are far more likely to favor it than classical genetic barriers without chromosomal
    changes. New evidence of the role of chromosomal rearrangements in parapatric
    speciation suggests that postzygotic isolation is often due to the accumulation
    of such incompatibilities. The model makes testable qualitative predictions about
    the genetic signature of speciation.
acknowledgement: "We thank A. Andrés, C. Bartolomé, J. Bertranpetit, F. Calafell,
  B. Charlesworth, D. Charlesworth, F. Depaulis, S. Gavrilets, T. Johnson, P. Keightley,
  M. Kirkpatrik, A. Kondrashov, H. Laayouni, X. Maside, M. Noor, D. Ortiz-Barrientos,\r\nL.
  Rieseberg, and T. Vines for valuable discussion and criticism. The detailed comments
  of B. Charlesworth, D. Charlesworth, and F. Depaulis greatly improved the original
  manuscript. AN is particularly grateful to X. Maside, who was a patient guide through
  the jungle of speciation. This work was supported by the NERC grant GR3/11635 (United
  Kingdom). AN is funded by the Ramón y Cajal Program (Spain)."
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
  full_name: Navarro, Arcadio
  last_name: Navarro
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Navarro A, Barton NH. Accumulating postzygotic isolation genes in parapatry:
    a new twist on chromosomal speciation. <i>Evolution; International Journal of
    Organic Evolution</i>. 2003;57(3):447-459. doi:<a href="https://doi.org/10.1111/j.0014-3820.2003.tb01537.x">10.1111/j.0014-3820.2003.tb01537.x</a>'
  apa: 'Navarro, A., &#38; Barton, N. H. (2003). Accumulating postzygotic isolation
    genes in parapatry: a new twist on chromosomal speciation. <i>Evolution; International
    Journal of Organic Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.0014-3820.2003.tb01537.x">https://doi.org/10.1111/j.0014-3820.2003.tb01537.x</a>'
  chicago: 'Navarro, Arcadio, and Nicholas H Barton. “Accumulating Postzygotic Isolation
    Genes in Parapatry: A New Twist on Chromosomal Speciation.” <i>Evolution; International
    Journal of Organic Evolution</i>. Wiley-Blackwell, 2003. <a href="https://doi.org/10.1111/j.0014-3820.2003.tb01537.x">https://doi.org/10.1111/j.0014-3820.2003.tb01537.x</a>.'
  ieee: 'A. Navarro and N. H. Barton, “Accumulating postzygotic isolation genes in
    parapatry: a new twist on chromosomal speciation,” <i>Evolution; International
    Journal of Organic Evolution</i>, vol. 57, no. 3. Wiley-Blackwell, pp. 447–459,
    2003.'
  ista: 'Navarro A, Barton NH. 2003. Accumulating postzygotic isolation genes in parapatry:
    a new twist on chromosomal speciation. Evolution; International Journal of Organic
    Evolution. 57(3), 447–459.'
  mla: 'Navarro, Arcadio, and Nicholas H. Barton. “Accumulating Postzygotic Isolation
    Genes in Parapatry: A New Twist on Chromosomal Speciation.” <i>Evolution; International
    Journal of Organic Evolution</i>, vol. 57, no. 3, Wiley-Blackwell, 2003, pp. 447–59,
    doi:<a href="https://doi.org/10.1111/j.0014-3820.2003.tb01537.x">10.1111/j.0014-3820.2003.tb01537.x</a>.'
  short: A. Navarro, N.H. Barton, Evolution; International Journal of Organic Evolution
    57 (2003) 447–459.
date_created: 2018-12-11T12:07:52Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2024-01-23T10:21:57Z
day: '01'
doi: 10.1111/j.0014-3820.2003.tb01537.x
extern: '1'
external_id:
  pmid:
  - '12703935 '
fulldoi: https://doi.org/10.1111/j.0014-3820.2003.tb01537.x
intvolume: '        57'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 447 - 459
pmid: 1
publication: Evolution; International Journal of Organic Evolution
publication_identifier:
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1840'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal
  speciation'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 57
year: '2003'
...
---
_id: '4255'
abstract:
- lang: eng
  text: 'Humans and their closest evolutionary relatives, the chimpanzees, differ
    in ∼1.24% of their genomic DNA sequences. The fraction of these changes accumulated
    during the speciation processes that have separated the two lineages may be of
    special relevance in understanding the basis of their differences. We analyzed
    human and chimpanzee sequence data to search for the patterns of divergence and
    polymorphism predicted by a theoretical model of speciation. According to the
    model, positively selected changes should accumulate in chromosomes that present
    fixed structural differences, such as inversions, between the two species. Protein
    evolution was more than 2.2 times faster in chromosomes that had undergone structural
    rearrangements compared with colinear chromosomes. Also, nucleotide variability
    is slightly lower in rearranged chromosomes. These patterns of divergence and
    polymorphism may be, at least in part, the molecular footprint of speciation events
    in the human and chimpanzee lineages. '
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
  full_name: Navarro, Arcadio
  last_name: Navarro
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Navarro A, Barton NH. Chromosomal speciation and molecular divergence -- Accelerated
    evolution in rearranged chromosomes. <i>Science</i>. 2003;300(5617):321-324. doi:<a
    href="https://doi.org/10.1126/science.1080600 ">10.1126/science.1080600 </a>
  apa: Navarro, A., &#38; Barton, N. H. (2003). Chromosomal speciation and molecular
    divergence -- Accelerated evolution in rearranged chromosomes. <i>Science</i>.
    American Association for the Advancement of Science. <a href="https://doi.org/10.1126/science.1080600
    ">https://doi.org/10.1126/science.1080600 </a>
  chicago: Navarro, Arcadio, and Nicholas H Barton. “Chromosomal Speciation and Molecular
    Divergence -- Accelerated Evolution in Rearranged Chromosomes.” <i>Science</i>.
    American Association for the Advancement of Science, 2003. <a href="https://doi.org/10.1126/science.1080600
    ">https://doi.org/10.1126/science.1080600 </a>.
  ieee: A. Navarro and N. H. Barton, “Chromosomal speciation and molecular divergence
    -- Accelerated evolution in rearranged chromosomes,” <i>Science</i>, vol. 300,
    no. 5617. American Association for the Advancement of Science, pp. 321–324, 2003.
  ista: Navarro A, Barton NH. 2003. Chromosomal speciation and molecular divergence
    -- Accelerated evolution in rearranged chromosomes. Science. 300(5617), 321–324.
  mla: Navarro, Arcadio, and Nicholas H. Barton. “Chromosomal Speciation and Molecular
    Divergence -- Accelerated Evolution in Rearranged Chromosomes.” <i>Science</i>,
    vol. 300, no. 5617, American Association for the Advancement of Science, 2003,
    pp. 321–24, doi:<a href="https://doi.org/10.1126/science.1080600 ">10.1126/science.1080600
    </a>.
  short: A. Navarro, N.H. Barton, Science 300 (2003) 321–324.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-04-11T00:00:00Z
date_updated: 2024-02-26T13:37:51Z
day: '11'
doi: '10.1126/science.1080600 '
extern: '1'
external_id:
  pmid:
  - ' 12690198'
fulldoi: 'https://doi.org/10.1126/science.1080600 '
intvolume: '       300'
issue: '5617'
language:
- iso: eng
month: '04'
oa_version: None
page: 321 - 324
pmid: 1
publication: Science
publication_identifier:
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '1841'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chromosomal speciation and molecular divergence -- Accelerated evolution in
  rearranged chromosomes
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 300
year: '2003'
...
---
_id: '4256'
abstract:
- lang: eng
  text: Artificial Life models may shed new light on the long-standing challenge for
    evolutionary biology of explaining the origins of complex organs. Real progress
    on this issue, however, requires Artificial Life researchers to take seriously
    the tools and insights from population genetics.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Willem
  full_name: Zuidema, Willem
  last_name: Zuidema
citation:
  ama: Barton NH, Zuidema W. The erratic path towards complexity. <i>Current Biology</i>.
    2003;13(16):R649-R651. doi:<a href="https://doi.org/10.1016/S0960-9822(03)00573-6">10.1016/S0960-9822(03)00573-6</a>
  apa: Barton, N. H., &#38; Zuidema, W. (2003). The erratic path towards complexity.
    <i>Current Biology</i>. Cell Press. <a href="https://doi.org/10.1016/S0960-9822(03)00573-6">https://doi.org/10.1016/S0960-9822(03)00573-6</a>
  chicago: Barton, Nicholas H, and Willem Zuidema. “The Erratic Path towards Complexity.”
    <i>Current Biology</i>. Cell Press, 2003. <a href="https://doi.org/10.1016/S0960-9822(03)00573-6">https://doi.org/10.1016/S0960-9822(03)00573-6</a>.
  ieee: N. H. Barton and W. Zuidema, “The erratic path towards complexity,” <i>Current
    Biology</i>, vol. 13, no. 16. Cell Press, pp. R649–R651, 2003.
  ista: Barton NH, Zuidema W. 2003. The erratic path towards complexity. Current Biology.
    13(16), R649–R651.
  mla: Barton, Nicholas H., and Willem Zuidema. “The Erratic Path towards Complexity.”
    <i>Current Biology</i>, vol. 13, no. 16, Cell Press, 2003, pp. R649–51, doi:<a
    href="https://doi.org/10.1016/S0960-9822(03)00573-6">10.1016/S0960-9822(03)00573-6</a>.
  short: N.H. Barton, W. Zuidema, Current Biology 13 (2003) R649–R651.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-08-19T00:00:00Z
date_updated: 2024-01-23T09:41:33Z
day: '19'
doi: 10.1016/S0960-9822(03)00573-6
extern: '1'
fulldoi: https://doi.org/10.1016/S0960-9822(03)00573-6
intvolume: '        13'
issue: '16'
language:
- iso: eng
month: '08'
oa_version: Published Version
page: R649 - R651
publication: Current Biology
publication_identifier:
  issn:
  - 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1838'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The erratic path towards complexity
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2003'
...
---
_id: '4257'
abstract:
- lang: eng
  text: Variation within a species may be structured both geographically and by genetic
    background. We review the effects of such structuring on neutral variants, using
    a framework based on the coalescent process. Short-term effects of sex differences
    and age structure can be averaged out using fast timescale approximations, allowing
    a simple general treatment of effective population size and migration. We consider
    the effects of geographic structure on variation within and between local populations,
    first in general terms, and then for specific migration models. We discuss the
    close parallels between geographic structure and stable types of genetic structure
    caused by selection, including balancing selection and background selection. The
    effects of departures from stability, such as selective sweeps and population
    bottlenecks, are also described. Methods for distinguishing population history
    from the effects of ongoing gene flow are discussed. We relate the theoretical
    results to observed patterns of variation in natural populations.
article_processing_charge: No
article_type: original
author:
- first_name: Brian
  full_name: Charlesworth, Brian
  last_name: Charlesworth
- first_name: Deborah
  full_name: Charlesworth, Deborah
  last_name: Charlesworth
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Charlesworth B, Charlesworth D, Barton NH. The effects of genetic and geographic
    structure on neutral variation. <i>Annual Review of Ecology and Systematics</i>.
    2003;34:99-125. doi:<a href="https://doi.org/10.1146/annurev.ecolsys.34.011802.132359">10.1146/annurev.ecolsys.34.011802.132359</a>
  apa: Charlesworth, B., Charlesworth, D., &#38; Barton, N. H. (2003). The effects
    of genetic and geographic structure on neutral variation. <i>Annual Review of
    Ecology and Systematics</i>. Annual Reviews. <a href="https://doi.org/10.1146/annurev.ecolsys.34.011802.132359">https://doi.org/10.1146/annurev.ecolsys.34.011802.132359</a>
  chicago: Charlesworth, Brian, Deborah Charlesworth, and Nicholas H Barton. “The
    Effects of Genetic and Geographic Structure on Neutral Variation.” <i>Annual Review
    of Ecology and Systematics</i>. Annual Reviews, 2003. <a href="https://doi.org/10.1146/annurev.ecolsys.34.011802.132359">https://doi.org/10.1146/annurev.ecolsys.34.011802.132359</a>.
  ieee: B. Charlesworth, D. Charlesworth, and N. H. Barton, “The effects of genetic
    and geographic structure on neutral variation,” <i>Annual Review of Ecology and
    Systematics</i>, vol. 34. Annual Reviews, pp. 99–125, 2003.
  ista: Charlesworth B, Charlesworth D, Barton NH. 2003. The effects of genetic and
    geographic structure on neutral variation. Annual Review of Ecology and Systematics.
    34, 99–125.
  mla: Charlesworth, Brian, et al. “The Effects of Genetic and Geographic Structure
    on Neutral Variation.” <i>Annual Review of Ecology and Systematics</i>, vol. 34,
    Annual Reviews, 2003, pp. 99–125, doi:<a href="https://doi.org/10.1146/annurev.ecolsys.34.011802.132359">10.1146/annurev.ecolsys.34.011802.132359</a>.
  short: B. Charlesworth, D. Charlesworth, N.H. Barton, Annual Review of Ecology and
    Systematics 34 (2003) 99–125.
date_created: 2018-12-11T12:07:53Z
date_published: 2003-11-01T00:00:00Z
date_updated: 2024-01-23T10:15:44Z
day: '01'
doi: 10.1146/annurev.ecolsys.34.011802.132359
extern: '1'
fulldoi: https://doi.org/10.1146/annurev.ecolsys.34.011802.132359
intvolume: '        34'
language:
- iso: eng
month: '11'
oa_version: None
page: 99 - 125
publication: Annual Review of Ecology and Systematics
publication_identifier:
  issn:
  - 1543-592X
publication_status: published
publisher: Annual Reviews
publist_id: '1839'
quality_controlled: '1'
status: public
title: The effects of genetic and geographic structure on neutral variation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 34
year: '2003'
...
---
_id: '4338'
abstract:
- lang: eng
  text: 'Mosaic hybrid zones arise when ecologically differentiated taxa hybridize
    across a network of habitat patches. Frequent interbreeding across a small-scale
    patchwork can erode species differences that might have been preserved in a clinal
    hybrid zone. In particular, the rapid breakdown of neutral divergence sets an
    upper limit to the time for which differences at marker loci can persist. We present
    here a case study of a mosaic hybrid zone between the fire-bellied toads Bombina
    bombina and B. variegata (Anura: Discoglossidae) near Apahida in Romania. In our
    20 × 20 km study area, we detected no evidence of a clinal transition but found
    a strong association between aquatic habitat and mean allele frequencies at four
    molecular markers. In particular, pure populations of B. bombina in ponds appear
    to cause massive introgression into the surrounding B. variegata gene pool found
    in temporary aquatic sites. Nevertheless, the genetic structure of these hybrid
    populations was remarkably similar to those of a previously studied transect near
    Pescenica (Croatia), which had both clinal and mosaic features: estimates of heterozygote
    deficit and linkage disequilibrium in each country are similar. In Apahida, the
    observed strong linkage disequilibria should stem from an imperfect habitat preference
    that guides most (but not all) adults into the habitats to which they are adapted.
    In the absence of a clinal structure, the inferred migration rate between habitats
    implies that associations between selected loci and neutral markers should break
    down rapidly. Although plausible selection strengths can maintain differentiation
    at those loci adapting the toads to either permanent or temporary breeding sites,
    the divergence at neutral markers must be transient. The hybrid zone may be approaching
    a state in which the gene pools are homogenized at all but the selected loci,
    not dissimilar from an early stage of sympatric divergence.'
acknowledgement: "We thank G. Mara and T. Galbena for enthusiastic field\r\nassistance,
  A. Hofmann and R. Sieglstetter for access to their\r\nunpublished data, B. Fo¨rg-Brey
  and G. Praetzel for help in\r\nthe lab. Helpful comments on a previous version of
  the man-\r\nuscript were provided by R. Ennos, J. Szymura, F. Balloux,\r\nJ. Bridle,
  L. Kruuk, F. Bonhomme, M. Arnold, and two anon-\r\nymous reviewers. We also thank
  A. Pinggera for providing\r\nthe cover illustration. This work was supported by
  Natural\r\nEnvironment Research Council studentships to THV and TRS\r\nand Deutsche
  Forschungsgemeinschaft grant Nu 51/2-1 to BN."
article_processing_charge: No
article_type: original
author:
- first_name: Timothy
  full_name: Vines, Timothy
  last_name: Vines
- first_name: S C
  full_name: Kohler, S C
  last_name: Kohler
- first_name: M
  full_name: Thiel, M
  last_name: Thiel
- first_name: Ioan
  full_name: Ghira, Ioan
  last_name: Ghira
- first_name: T R
  full_name: Sands, T R
  last_name: Sands
- first_name: Catriona
  full_name: Maccallum, Catriona
  last_name: Maccallum
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Beate
  full_name: Nürnberger, Beate
  last_name: Nürnberger
citation:
  ama: Vines T, Kohler SC, Thiel M, et al. On the maintenance of reproductive isolation
    in a mosaic hybrid zone between the toads Bombina bombina and B. variegata. <i>Evolution</i>.
    2003;57(8):1876-1888. doi:<a href="https://doi.org/10.1111/j.0014-3820.2003.tb00595.x">10.1111/j.0014-3820.2003.tb00595.x</a>
  apa: Vines, T., Kohler, S. C., Thiel, M., Ghira, I., Sands, T. R., Maccallum, C.,
    … Nürnberger, B. (2003). On the maintenance of reproductive isolation in a mosaic
    hybrid zone between the toads Bombina bombina and B. variegata. <i>Evolution</i>.
    Wiley-Blackwell. <a href="https://doi.org/10.1111/j.0014-3820.2003.tb00595.x">https://doi.org/10.1111/j.0014-3820.2003.tb00595.x</a>
  chicago: Vines, Timothy, S C Kohler, M Thiel, Ioan Ghira, T R Sands, Catriona Maccallum,
    Nicholas H Barton, and Beate Nürnberger. “On the Maintenance of Reproductive Isolation
    in a Mosaic Hybrid Zone between the Toads Bombina Bombina and B. Variegata.” <i>Evolution</i>.
    Wiley-Blackwell, 2003. <a href="https://doi.org/10.1111/j.0014-3820.2003.tb00595.x">https://doi.org/10.1111/j.0014-3820.2003.tb00595.x</a>.
  ieee: T. Vines <i>et al.</i>, “On the maintenance of reproductive isolation in a
    mosaic hybrid zone between the toads Bombina bombina and B. variegata,” <i>Evolution</i>,
    vol. 57, no. 8. Wiley-Blackwell, pp. 1876–1888, 2003.
  ista: Vines T, Kohler SC, Thiel M, Ghira I, Sands TR, Maccallum C, Barton NH, Nürnberger
    B. 2003. On the maintenance of reproductive isolation in a mosaic hybrid zone
    between the toads Bombina bombina and B. variegata. Evolution. 57(8), 1876–1888.
  mla: Vines, Timothy, et al. “On the Maintenance of Reproductive Isolation in a Mosaic
    Hybrid Zone between the Toads Bombina Bombina and B. Variegata.” <i>Evolution</i>,
    vol. 57, no. 8, Wiley-Blackwell, 2003, pp. 1876–88, doi:<a href="https://doi.org/10.1111/j.0014-3820.2003.tb00595.x">10.1111/j.0014-3820.2003.tb00595.x</a>.
  short: T. Vines, S.C. Kohler, M. Thiel, I. Ghira, T.R. Sands, C. Maccallum, N.H.
    Barton, B. Nürnberger, Evolution 57 (2003) 1876–1888.
date_created: 2018-12-11T12:08:20Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2024-01-23T09:16:43Z
day: '01'
doi: 10.1111/j.0014-3820.2003.tb00595.x
extern: '1'
fulldoi: https://doi.org/10.1111/j.0014-3820.2003.tb00595.x
intvolume: '        57'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 1876 - 1888
publication: Evolution
publication_identifier:
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1692'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the maintenance of reproductive isolation in a mosaic hybrid zone between
  the toads Bombina bombina and B. variegata
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 57
year: '2003'
...
---
_id: '17741'
abstract:
- lang: eng
  text: The recent discovery of a Gunn-Peterson (GP) trough in the spectrum of the
    redshift 6.28 SDSS quasar has raised the tantalizing possibility that we have
    detected the reionization of the universe. However, a neutral fraction (of hydrogen)
    as small as 0.1% is sufficient to cause the GP trough; hence, its detection alone
    cannot rule out reionization at a much earlier epoch. The cosmic microwave background
    (CMB) polarization anisotropy offers an alternative way to explore the dark age
    of the universe. We show that for most models constrained by the current CMB data
    and by the discovery of a GP trough (showing that reionization occurred at z >
    6.3), Microwave Anisotropy Probe (MAP) can detect the reionization signature in
    the polarization power spectrum. The expected 1 σ error on the measurement of
    the electron optical depth is around 0.03 with a weak dependence on the value
    of that optical depth. Such a constraint on the optical depth will allow MAP to
    achieve a 1 σ error on the amplitude of the primordial power spectrum of 6%. MAP
    with 2 yr (Planck with 1 yr) of observation can distinguish a model with 50% (6%)
    partial ionization between redshifts of 6.3 and 20 from a model in which hydrogen
    was completely neutral at redshifts greater than 6.3. Planck will be able to distinguish
    between different reionization histories even when they imply the same optical
    depth to electron scattering for the CMB photons.
article_processing_charge: No
article_type: original
author:
- first_name: Manoj
  full_name: Kaplinghat, Manoj
  last_name: Kaplinghat
- first_name: Mike
  full_name: Chu, Mike
  last_name: Chu
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Gilbert P.
  full_name: Holder, Gilbert P.
  last_name: Holder
- first_name: Lloyd
  full_name: Knox, Lloyd
  last_name: Knox
- first_name: Constantinos
  full_name: Skordis, Constantinos
  last_name: Skordis
citation:
  ama: Kaplinghat M, Chu M, Haiman Z, Holder GP, Knox L, Skordis C. Probing the reionization
    history of the universe using the cosmic microwave background polarization. <i>The
    Astrophysical Journal</i>. 2003;583(1):24-32. doi:<a href="https://doi.org/10.1086/344927">10.1086/344927</a>
  apa: Kaplinghat, M., Chu, M., Haiman, Z., Holder, G. P., Knox, L., &#38; Skordis,
    C. (2003). Probing the reionization history of the universe using the cosmic microwave
    background polarization. <i>The Astrophysical Journal</i>. American Astronomical
    Society. <a href="https://doi.org/10.1086/344927">https://doi.org/10.1086/344927</a>
  chicago: Kaplinghat, Manoj, Mike Chu, Zoltán Haiman, Gilbert P. Holder, Lloyd Knox,
    and Constantinos Skordis. “Probing the Reionization History of the Universe Using
    the Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>.
    American Astronomical Society, 2003. <a href="https://doi.org/10.1086/344927">https://doi.org/10.1086/344927</a>.
  ieee: M. Kaplinghat, M. Chu, Z. Haiman, G. P. Holder, L. Knox, and C. Skordis, “Probing
    the reionization history of the universe using the cosmic microwave background
    polarization,” <i>The Astrophysical Journal</i>, vol. 583, no. 1. American Astronomical
    Society, pp. 24–32, 2003.
  ista: Kaplinghat M, Chu M, Haiman Z, Holder GP, Knox L, Skordis C. 2003. Probing
    the reionization history of the universe using the cosmic microwave background
    polarization. The Astrophysical Journal. 583(1), 24–32.
  mla: Kaplinghat, Manoj, et al. “Probing the Reionization History of the Universe
    Using the Cosmic Microwave Background Polarization.” <i>The Astrophysical Journal</i>,
    vol. 583, no. 1, American Astronomical Society, 2003, pp. 24–32, doi:<a href="https://doi.org/10.1086/344927">10.1086/344927</a>.
  short: M. Kaplinghat, M. Chu, Z. Haiman, G.P. Holder, L. Knox, C. Skordis, The Astrophysical
    Journal 583 (2003) 24–32.
date_created: 2024-09-06T09:25:08Z
date_published: 2003-01-20T00:00:00Z
date_updated: 2024-09-26T14:15:21Z
day: '20'
doi: 10.1086/344927
extern: '1'
fulldoi: https://doi.org/10.1086/344927
intvolume: '       583'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/344927
month: '01'
oa: 1
oa_version: Published Version
page: 24-32
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probing the reionization history of the universe using the cosmic microwave
  background polarization
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 583
year: '2003'
...
---
_id: '17748'
abstract:
- lang: eng
  text: 'Recent results by the WMAP satellite suggest that the intergalactic medium
    was significantly reionized at redshifts as high as z~17. At this early epoch,
    the first ionizing sources likely appeared in the shallow potential wells of mini-halos
    with virial temperatures T < 10^4 K. Once such an ionizing source turns off, its
    surrounding HII region Compton cools and recombines. Nonetheless, we show that
    the ``fossil'''' HII regions left behind remain at high adiabats, prohibiting
    gas accretion and cooling in subsequent generations of mini-halos. Thus, early
    star formation is self-limiting. We quantify this effect to show that star formation
    in mini-halos cannot account for the bulk of the electron scattering opacity measured
    by WMAP, which must be due to more massive objects. We argue that gas entropy,
    rather than IGM metallicity, regulates the evolution of the global ionizing emissivity,
    and impedes full reionization until lower redshifts. We discuss several important
    consequences of this early entropy floor for reionization. It reduces gas clumping,
    curtailing the required photon budget for reionization. An entropy floor also
    prevents H2 formation and cooling, due to reduced gas densities: it greatly enhances
    feedback from UV photodissociation of H2. An early X-ray background would also
    furnish an entropy floor to the entire IGM; thus, X-rays impede rather than enhance
    H2 formation. Future 21cm observations may probe the topology of fossil HII regions.'
alternative_title:
- Fossil H ii regions
article_processing_charge: No
article_type: original
author:
- first_name: S. Peng
  full_name: Oh, S. Peng
  last_name: Oh
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
citation:
  ama: 'Oh SP, Haiman Z. Fossil H ii regions: Self-limiting star formation at high
    redshift. <i>Monthly Notices of the Royal Astronomical Society</i>. 2003;346(2):456-472.
    doi:<a href="https://doi.org/10.1046/j.1365-2966.2003.07103.x">10.1046/j.1365-2966.2003.07103.x</a>'
  apa: 'Oh, S. P., &#38; Haiman, Z. (2003). Fossil H ii regions: Self-limiting star
    formation at high redshift. <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press. <a href="https://doi.org/10.1046/j.1365-2966.2003.07103.x">https://doi.org/10.1046/j.1365-2966.2003.07103.x</a>'
  chicago: 'Oh, S. Peng, and Zoltán Haiman. “Fossil H Ii Regions: Self-Limiting Star
    Formation at High Redshift.” <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press, 2003. <a href="https://doi.org/10.1046/j.1365-2966.2003.07103.x">https://doi.org/10.1046/j.1365-2966.2003.07103.x</a>.'
  ieee: 'S. P. Oh and Z. Haiman, “Fossil H ii regions: Self-limiting star formation
    at high redshift,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol.
    346, no. 2. Oxford University Press, pp. 456–472, 2003.'
  ista: 'Oh SP, Haiman Z. 2003. Fossil H ii regions: Self-limiting star formation
    at high redshift. Monthly Notices of the Royal Astronomical Society. 346(2), 456–472.'
  mla: 'Oh, S. Peng, and Zoltán Haiman. “Fossil H Ii Regions: Self-Limiting Star Formation
    at High Redshift.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol.
    346, no. 2, Oxford University Press, 2003, pp. 456–72, doi:<a href="https://doi.org/10.1046/j.1365-2966.2003.07103.x">10.1046/j.1365-2966.2003.07103.x</a>.'
  short: S.P. Oh, Z. Haiman, Monthly Notices of the Royal Astronomical Society 346
    (2003) 456–472.
date_created: 2024-09-06T09:36:17Z
date_published: 2003-12-01T00:00:00Z
date_updated: 2024-09-26T15:00:48Z
day: '01'
doi: 10.1046/j.1365-2966.2003.07103.x
extern: '1'
fulldoi: https://doi.org/10.1046/j.1365-2966.2003.07103.x
intvolume: '       346'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1046/j.1365-2966.2003.07103.x
month: '12'
oa: 1
oa_version: Published Version
page: 456-472
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Fossil H ii regions: Self-limiting star formation at high redshift'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 346
year: '2003'
...
---
_id: '17750'
abstract:
- lang: eng
  text: We present the discovery of three new quasars at z>6 in 1300 deg^2 of SDSS
    imaging data, J114816.64+525150.3 (z=6.43), J104845.05+463718.3 (z=6.23) and J163033.90+401209.6
    (z=6.05). The first two objects have weak Ly alpha emission lines; their redshifts
    are determined from the positions of the Lyman break. They are only accurate to
    0.05 and could be affected by the presence of broad absorption line systems. The
    last object has a Ly alpha strength more typical of lower redshift quasars. Based
    on a sample of six quasars at z>5.7 that cover 2870 deg^2 presented in this paper
    and in Paper I, we estimate the comoving density of luminous quasars at z 6 and
    M_{1450} < -26.8 to be (8 +/- 3)x10^{-10} Mpc^{-3} (for H_0 = 50 km/s/Mpc, Omega
    = 1). HST imaging of two z>5.7 quasars and high-resolution ground-based images
    (seeing 0.4'') of three additional z>5.7 quasars show that none of them is gravitationally
    lensed. The luminosity distribution of the high-redshfit quasar sample suggests
    the bright end slope of the quasar luminosity function at z 6 is shallower than
    Psi L^{-3.5} (2-sigma), consistent with the absence of strongly lensed objects.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaohui
  full_name: Fan, Xiaohui
  last_name: Fan
- first_name: Michael A.
  full_name: Strauss, Michael A.
  last_name: Strauss
- first_name: Donald P.
  full_name: Schneider, Donald P.
  last_name: Schneider
- first_name: Robert H.
  full_name: Becker, Robert H.
  last_name: Becker
- first_name: Richard L.
  full_name: White, Richard L.
  last_name: White
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Michael
  full_name: Gregg, Michael
  last_name: Gregg
- first_name: Laura
  full_name: Pentericci, Laura
  last_name: Pentericci
- first_name: Eva K.
  full_name: Grebel, Eva K.
  last_name: Grebel
- first_name: Vijay K.
  full_name: Narayanan, Vijay K.
  last_name: Narayanan
- first_name: Yeong-Shang
  full_name: Loh, Yeong-Shang
  last_name: Loh
- first_name: Gordon T.
  full_name: Richards, Gordon T.
  last_name: Richards
- first_name: James E.
  full_name: Gunn, James E.
  last_name: Gunn
- first_name: Robert H.
  full_name: Lupton, Robert H.
  last_name: Lupton
- first_name: Gillian R.
  full_name: Knapp, Gillian R.
  last_name: Knapp
- first_name: Željko
  full_name: Ivezić, Željko
  last_name: Ivezić
- first_name: W. N.
  full_name: Brandt, W. N.
  last_name: Brandt
- first_name: Matthew
  full_name: Collinge, Matthew
  last_name: Collinge
- first_name: Lei
  full_name: Hao, Lei
  last_name: Hao
- first_name: Daniel
  full_name: Harbeck, Daniel
  last_name: Harbeck
- first_name: Francisco
  full_name: Prada, Francisco
  last_name: Prada
- first_name: Joop
  full_name: Schaye, Joop
  last_name: Schaye
- first_name: Iskra
  full_name: Strateva, Iskra
  last_name: Strateva
- first_name: Nadia
  full_name: Zakamska, Nadia
  last_name: Zakamska
- first_name: Scott
  full_name: Anderson, Scott
  last_name: Anderson
- first_name: Jon
  full_name: Brinkmann, Jon
  last_name: Brinkmann
- first_name: Neta A.
  full_name: Bahcall, Neta A.
  last_name: Bahcall
- first_name: Don Q.
  full_name: Lamb, Don Q.
  last_name: Lamb
- first_name: Sadanori
  full_name: Okamura, Sadanori
  last_name: Okamura
- first_name: Alex
  full_name: Szalay, Alex
  last_name: Szalay
- first_name: Donald G.
  full_name: York, Donald G.
  last_name: York
citation:
  ama: Fan X, Strauss MA, Schneider DP, et al. A survey of z &#62; 5.7 quasars in
    the Sloan Digital Sky Survey. II. Discovery of three additional quasars at z &#62;
    6. <i>The Astronomical Journal</i>. 2003;125(4):1649-1659. doi:<a href="https://doi.org/10.1086/368246">10.1086/368246</a>
  apa: Fan, X., Strauss, M. A., Schneider, D. P., Becker, R. H., White, R. L., Haiman,
    Z., … York, D. G. (2003). A survey of z &#62; 5.7 quasars in the Sloan Digital
    Sky Survey. II. Discovery of three additional quasars at z &#62; 6. <i>The Astronomical
    Journal</i>. American Astronomical Society. <a href="https://doi.org/10.1086/368246">https://doi.org/10.1086/368246</a>
  chicago: Fan, Xiaohui, Michael A. Strauss, Donald P. Schneider, Robert H. Becker,
    Richard L. White, Zoltán Haiman, Michael Gregg, et al. “A Survey of z &#62; 5.7
    Quasars in the Sloan Digital Sky Survey. II. Discovery of Three Additional Quasars
    at z &#62; 6.” <i>The Astronomical Journal</i>. American Astronomical Society,
    2003. <a href="https://doi.org/10.1086/368246">https://doi.org/10.1086/368246</a>.
  ieee: X. Fan <i>et al.</i>, “A survey of z &#62; 5.7 quasars in the Sloan Digital
    Sky Survey. II. Discovery of three additional quasars at z &#62; 6,” <i>The Astronomical
    Journal</i>, vol. 125, no. 4. American Astronomical Society, pp. 1649–1659, 2003.
  ista: Fan X, Strauss MA, Schneider DP, Becker RH, White RL, Haiman Z, Gregg M, Pentericci
    L, Grebel EK, Narayanan VK, Loh Y-S, Richards GT, Gunn JE, Lupton RH, Knapp GR,
    Ivezić Ž, Brandt WN, Collinge M, Hao L, Harbeck D, Prada F, Schaye J, Strateva
    I, Zakamska N, Anderson S, Brinkmann J, Bahcall NA, Lamb DQ, Okamura S, Szalay
    A, York DG. 2003. A survey of z &#62; 5.7 quasars in the Sloan Digital Sky Survey.
    II. Discovery of three additional quasars at z &#62; 6. The Astronomical Journal.
    125(4), 1649–1659.
  mla: Fan, Xiaohui, et al. “A Survey of z &#62; 5.7 Quasars in the Sloan Digital
    Sky Survey. II. Discovery of Three Additional Quasars at z &#62; 6.” <i>The Astronomical
    Journal</i>, vol. 125, no. 4, American Astronomical Society, 2003, pp. 1649–59,
    doi:<a href="https://doi.org/10.1086/368246">10.1086/368246</a>.
  short: X. Fan, M.A. Strauss, D.P. Schneider, R.H. Becker, R.L. White, Z. Haiman,
    M. Gregg, L. Pentericci, E.K. Grebel, V.K. Narayanan, Y.-S. Loh, G.T. Richards,
    J.E. Gunn, R.H. Lupton, G.R. Knapp, Ž. Ivezić, W.N. Brandt, M. Collinge, L. Hao,
    D. Harbeck, F. Prada, J. Schaye, I. Strateva, N. Zakamska, S. Anderson, J. Brinkmann,
    N.A. Bahcall, D.Q. Lamb, S. Okamura, A. Szalay, D.G. York, The Astronomical Journal
    125 (2003) 1649–1659.
date_created: 2024-09-06T09:38:08Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2024-09-30T07:33:02Z
day: '01'
doi: 10.1086/368246
extern: '1'
fulldoi: https://doi.org/10.1086/368246
intvolume: '       125'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/368246
month: '04'
oa: 1
oa_version: Published Version
page: 1649-1659
publication: The Astronomical Journal
publication_identifier:
  issn:
  - 0004-6256
  - 1538-3881
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A survey of z > 5.7 quasars in the Sloan Digital Sky Survey. II. Discovery
  of three additional quasars at z > 6
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 125
year: '2003'
...
---
_id: '17754'
abstract:
- lang: eng
  text: 'The recent discovery of a high optical depth tau to Thomson scattering from
    the WMAP data implies that significant reionization took place at redshifts z~15.
    This discovery has important implications for the sources of reionization, and
    allows, for the first time, constraints to be placed on physical reionization
    scenarios out to redshift z~20. Using a new suite of semi-analytic reionization
    models, we show that the high value of tau requires a surprisingly high efficiency
    epsilon of the first generation of UV sources for injecting ionizing photons into
    the intergalactic medium. We find that no simple reionization model can be consistent
    with the combination of the WMAP result with data from the z<6.5 universe. Satisfying
    both constraints requires either of the following: (i) H_2 molecules form efficiently
    at z~20, survive feedback processes, and allow UV sources in halos with virial
    temperatures below Tvir=10^4 K to contribute substantially to reionization, or
    (ii) the efficiency epsilon in halos with Tvir>10^4K decreased by a factor of
    ~ 30 between (z~20) and (z~6). We discuss the relevant physical issues to produce
    either scenario, and argue that both options are viable, and allowed by current
    data. In detailed models of the reionization history, we find that the evolution
    of the ionized fractions in the two scenarios have distinctive features that Planck
    can distinguish at 3 sigma significance. At the high WMAP value for tau, Planck
    will also be able to provide tight statistical constraints on reionization model
    parameters, and elucidate much of the physics at the end of the Dark Ages. The
    sources responsible for the high optical depth discovered by WMAP should be directly
    detectable out to z~15 by the James Webb Space Telescope.'
article_processing_charge: No
article_type: original
author:
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
- first_name: Gilbert P.
  full_name: Holder, Gilbert P.
  last_name: Holder
citation:
  ama: Haiman Z, Holder GP. The reionization history at high redshifts. I. Physical
    models and new constraints from cosmic microwave background polarization. <i>The
    Astrophysical Journal</i>. 2003;595(1):1-12. doi:<a href="https://doi.org/10.1086/377337">10.1086/377337</a>
  apa: Haiman, Z., &#38; Holder, G. P. (2003). The reionization history at high redshifts.
    I. Physical models and new constraints from cosmic microwave background polarization.
    <i>The Astrophysical Journal</i>. American Astronomical Society. <a href="https://doi.org/10.1086/377337">https://doi.org/10.1086/377337</a>
  chicago: Haiman, Zoltán, and Gilbert P. Holder. “The Reionization History at High
    Redshifts. I. Physical Models and New Constraints from Cosmic Microwave Background
    Polarization.” <i>The Astrophysical Journal</i>. American Astronomical Society,
    2003. <a href="https://doi.org/10.1086/377337">https://doi.org/10.1086/377337</a>.
  ieee: Z. Haiman and G. P. Holder, “The reionization history at high redshifts. I.
    Physical models and new constraints from cosmic microwave background polarization,”
    <i>The Astrophysical Journal</i>, vol. 595, no. 1. American Astronomical Society,
    pp. 1–12, 2003.
  ista: Haiman Z, Holder GP. 2003. The reionization history at high redshifts. I.
    Physical models and new constraints from cosmic microwave background polarization.
    The Astrophysical Journal. 595(1), 1–12.
  mla: Haiman, Zoltán, and Gilbert P. Holder. “The Reionization History at High Redshifts.
    I. Physical Models and New Constraints from Cosmic Microwave Background Polarization.”
    <i>The Astrophysical Journal</i>, vol. 595, no. 1, American Astronomical Society,
    2003, pp. 1–12, doi:<a href="https://doi.org/10.1086/377337">10.1086/377337</a>.
  short: Z. Haiman, G.P. Holder, The Astrophysical Journal 595 (2003) 1–12.
date_created: 2024-09-06T09:42:24Z
date_published: 2003-09-20T00:00:00Z
date_updated: 2024-09-30T08:02:54Z
day: '20'
doi: 10.1086/377337
extern: '1'
fulldoi: https://doi.org/10.1086/377337
intvolume: '       595'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1086/377337
month: '09'
oa: 1
oa_version: Published Version
page: 1-12
publication: The Astrophysical Journal
publication_identifier:
  issn:
  - 0004-637X
  - 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: The reionization history at high redshifts. I. Physical models and new constraints
  from cosmic microwave background polarization
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 595
year: '2003'
...
