---
OA_type: closed access
_id: '2629'
abstract:
- lang: eng
text: The release of neurotransmitters is modulated by presynaptic metabotropic
glutamate receptors (mGluRs), which show a highly selective expression and subcellular
location in glutamatergic terminals in the hippocampus. Using immunocytochemistry,
we investigated whether one of the receptors, mGluR7, whose level of expression
is governed by the postsynaptic target, was present in GABAergic terminals and
whether such terminals targeted particular cells. A total of 165 interneuron dendritic
profiles receiving 466 synapses (82% mGluR7a-positive) were analysed. The presynaptic
active zones of most GAD-(77%) or GABA-positive (94%) synaptic boutons on interneurons
innervated by mGluR7a-enriched glutamatergic terminals (mGluR7a-decorated) were
immunopositive for mGluR7a. GABAergic terminals on pyramidal cells and most other
interneurons in str. oriens were mGluR7a-immunonegative. The mGluR7a-decorated
cells were mostly somatostatin- and mGluR1α-immunopositive neurons in str. oriens
and the alveus. Their GABAergic input mainly originated from VIP-positive terminals,
90% of which expressed high levels of mGluR7a in the presynaptic active zone.
Parvalbumin-positive synaptic terminals were rare on mGluR7a-decorated cells,
but on these neurons 73% of them were mGluR7a-immunopositive. Some type II synapses
innervating interneurons were immunopositive for mGluR7b, as were some type I
synapses. Because not all target cells of VIP-positive neurons are known it has
not been possible to determine whether mGluR7 is expressed in a target-cell-specific
manner in the terminals of single GABAergic cells. The activation of mGluR7 may
decrease GABA release to mGluR7-decorated cells at times of high pyramidal cell
activity, which elevates extracellular glutamate levels. Alternatively, the presynaptic
receptor may be activated by as yet unidentified endogenous ligands released by
the GABAergic terminals or the postsynaptic dendrites.
article_processing_charge: No
article_type: original
author:
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
- first_name: Yannis
full_name: Dalezios, Yannis
last_name: Dalezios
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: John
full_name: Roberts, John
last_name: Roberts
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Somogyi P, Dalezios Y, Luján R, Roberts J, Watanabe M, Shigemoto R. High level
of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals
innervating interneurons in the rat hippocampus. European Journal of Neuroscience.
2003;17(12):2503-2520. doi:10.1046/j.1460-9568.2003.02697.x
apa: Somogyi, P., Dalezios, Y., Luján, R., Roberts, J., Watanabe, M., & Shigemoto,
R. (2003). High level of mGluR7 in the presynaptic active zones of select populations
of GABAergic terminals innervating interneurons in the rat hippocampus. European
Journal of Neuroscience. Wiley. https://doi.org/10.1046/j.1460-9568.2003.02697.x
chicago: Somogyi, Péter, Yannis Dalezios, Rafael Luján, John Roberts, Masahiko Watanabe,
and Ryuichi Shigemoto. “High Level of MGluR7 in the Presynaptic Active Zones of
Select Populations of GABAergic Terminals Innervating Interneurons in the Rat
Hippocampus.” European Journal of Neuroscience. Wiley, 2003. https://doi.org/10.1046/j.1460-9568.2003.02697.x.
ieee: P. Somogyi, Y. Dalezios, R. Luján, J. Roberts, M. Watanabe, and R. Shigemoto,
“High level of mGluR7 in the presynaptic active zones of select populations of
GABAergic terminals innervating interneurons in the rat hippocampus,” European
Journal of Neuroscience, vol. 17, no. 12. Wiley, pp. 2503–2520, 2003.
ista: Somogyi P, Dalezios Y, Luján R, Roberts J, Watanabe M, Shigemoto R. 2003.
High level of mGluR7 in the presynaptic active zones of select populations of
GABAergic terminals innervating interneurons in the rat hippocampus. European
Journal of Neuroscience. 17(12), 2503–2520.
mla: Somogyi, Péter, et al. “High Level of MGluR7 in the Presynaptic Active Zones
of Select Populations of GABAergic Terminals Innervating Interneurons in the Rat
Hippocampus.” European Journal of Neuroscience, vol. 17, no. 12, Wiley,
2003, pp. 2503–20, doi:10.1046/j.1460-9568.2003.02697.x.
short: P. Somogyi, Y. Dalezios, R. Luján, J. Roberts, M. Watanabe, R. Shigemoto,
European Journal of Neuroscience 17 (2003) 2503–2520.
date_created: 2018-12-11T11:58:46Z
date_published: 2003-06-23T00:00:00Z
date_updated: 2026-05-22T11:09:56Z
day: '23'
doi: 10.1046/j.1460-9568.2003.02697.x
extern: '1'
external_id:
pmid:
- '12823458'
intvolume: ' 17'
issue: '12'
language:
- iso: eng
month: '06'
oa_version: None
page: 2503 - 2520
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
eissn:
- 1460-9568
issn:
- 0953-816X
publication_status: published
publisher: Wiley
publist_id: '4269'
quality_controlled: '1'
scopus_import: '1'
status: public
title: High level of mGluR7 in the presynaptic active zones of select populations
of GABAergic terminals innervating interneurons in the rat hippocampus
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 17
year: '2003'
...
---
OA_type: closed access
_id: '2630'
abstract:
- lang: eng
text: Taste-metabotropic glutamate receptor 4 (taste-mGluR4) and the heteromers
of T1R1 and T1R3 are candidate receptors involved in the sense of umami (monosodium
glutamate) taste. Although the expression of group III mGluRs (taste-mGluR4) has
been demonstrated in taste tissues, no mention has been made of the expression
of group I mGluRs (mGluR1 and mGluR5) in taste tissues. We examined the expression
of mGluR1 and mGluR5 in rat gustatory tissues by using reverse transcription-polymerase
chain reaction (RT-PCR), in situ hybridization, immunohistochemistry and immunoelectron
microscopy. RT-PCR assay showed that mGluR1α and mGluR1β mRNAs were expressed
in circumvallate papillae, but mGluR5 mRNA was not expressed. The positive signals
of mGluR1 mRNA were detected only in circumvallate taste buds by in situ hybridization
analysis. In cryosections of fungiform, foliate and circumvallate papillae, the
antibody against mGluRla gave intense labeling on the taste hairs in all taste
pores examined. In the developing taste buds, the positive signals of mGluR1α
in taste hairs gradually increased with the increase in number of taste bud cells.
These results show that, in addition to taste-mGluR4 and the heteromer of T1R1
and T1R3, mGluR1α may function as a receptor for glutamate (umami) taste sensation.
article_processing_charge: No
article_type: original
author:
- first_name: Takashi
full_name: Toyono, Takashi
last_name: Toyono
- first_name: Yuji
full_name: Seta, Yuji
last_name: Seta
- first_name: Shinji
full_name: Kataoka, Shinji
last_name: Kataoka
- first_name: Shintaro
full_name: Kawano, Shintaro
last_name: Kawano
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kuniaki
full_name: Toyoshima, Kuniaki
last_name: Toyoshima
citation:
ama: Toyono T, Seta Y, Kataoka S, Kawano S, Shigemoto R, Toyoshima K. Expression
of metabotropic glutamate receptor group I in rat gustatory papillae. Cell
and Tissue Research. 2003;313:29-35. doi:10.1007/s00441-003-0740-2
apa: Toyono, T., Seta, Y., Kataoka, S., Kawano, S., Shigemoto, R., & Toyoshima,
K. (2003). Expression of metabotropic glutamate receptor group I in rat gustatory
papillae. Cell and Tissue Research. Springer Nature. https://doi.org/10.1007/s00441-003-0740-2
chicago: Toyono, Takashi, Yuji Seta, Shinji Kataoka, Shintaro Kawano, Ryuichi Shigemoto,
and Kuniaki Toyoshima. “Expression of Metabotropic Glutamate Receptor Group I
in Rat Gustatory Papillae.” Cell and Tissue Research. Springer Nature,
2003. https://doi.org/10.1007/s00441-003-0740-2.
ieee: T. Toyono, Y. Seta, S. Kataoka, S. Kawano, R. Shigemoto, and K. Toyoshima,
“Expression of metabotropic glutamate receptor group I in rat gustatory papillae,”
Cell and Tissue Research, vol. 313. Springer Nature, pp. 29–35, 2003.
ista: Toyono T, Seta Y, Kataoka S, Kawano S, Shigemoto R, Toyoshima K. 2003. Expression
of metabotropic glutamate receptor group I in rat gustatory papillae. Cell and
Tissue Research. 313, 29–35.
mla: Toyono, Takashi, et al. “Expression of Metabotropic Glutamate Receptor Group
I in Rat Gustatory Papillae.” Cell and Tissue Research, vol. 313, Springer
Nature, 2003, pp. 29–35, doi:10.1007/s00441-003-0740-2.
short: T. Toyono, Y. Seta, S. Kataoka, S. Kawano, R. Shigemoto, K. Toyoshima, Cell
and Tissue Research 313 (2003) 29–35.
date_created: 2018-12-11T11:58:46Z
date_published: 2003-07-01T00:00:00Z
date_updated: 2026-05-22T10:51:39Z
day: '01'
doi: 10.1007/s00441-003-0740-2
extern: '1'
external_id:
pmid:
- '12898387'
intvolume: ' 313'
language:
- iso: eng
month: '07'
oa_version: None
page: 29 - 35
pmid: 1
publication: Cell and Tissue Research
publication_identifier:
eissn:
- 1432-0878
issn:
- 0302-766X
publication_status: published
publisher: Springer Nature
publist_id: '4267'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expression of metabotropic glutamate receptor group I in rat gustatory papillae
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 313
year: '2003'
...
---
OA_type: closed access
_id: '2631'
abstract:
- lang: eng
text: Cyclic ADP-ribose (cADP-ribose) is a putative second messenger or modulator.
However, the role of cADP-ribose in the downstream signals of the metabotropic
glutamate receptors (mGluRs) is unclear. Here, we show that glutamate stimulates
ADP-ribosyl cyclase activity in rat or mouse crude membranes of retina via group
III mGluRs or in superior cervical ganglion via group I mGluRs. The retina of
mGluR6-deficient mice showed no increase in the ADP-ribosyl cyclase level in response
to glutamate. GTP enhanced the initial rate of basal and glutamate-stimulated
cyclase activity. GTP-γ-S also stimulated basal activity. To determine whether
the coupling mode of mGluRs to ADP-ribosyl cyclase is a feature common to individual
cloned mGluRs, we expressed each mGluR subtype in NG108-15 neuroblastoma x glioma
hybrid cells. The glutamate-induced stimulation of the cyclase occurs preferentially
in NG108-15 cells over-expressing mGluRs1, 3, 5, and 6. Cells expressing mGluR2
or mGluRs4 and 7 exhibit inhibition or no coupling, respectively. Glutamate-induced
activation or inhibition of the cyclase activity was eliminated after pre-treatment
with cholera or pertussis toxin, respectively. Thus, the subtype-specific coupling
of mGluRs to ADP-ribosyl cyclase via G proteins suggests that some glutamate-evoked
neuronal functions are mediated by cADP-ribose.
article_processing_charge: No
article_type: original
author:
- first_name: Haruhiro
full_name: Higashida, Haruhiro
last_name: Higashida
- first_name: Jia
full_name: Zhang, Jia
last_name: Zhang
- first_name: Sumiko
full_name: Mochida, Sumiko
last_name: Mochida
- first_name: Xiao
full_name: Chen, Xiao
last_name: Chen
- first_name: Yeonsook
full_name: Shin, Yeonsook
last_name: Shin
- first_name: Mami
full_name: Noda, Mami
last_name: Noda
- first_name: Kazi
full_name: Hossain, Kazi
last_name: Hossain
- first_name: Naoto
full_name: Hoshi, Naoto
last_name: Hoshi
- first_name: Minako
full_name: Hashii, Minako
last_name: Hashii
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
- first_name: Yutaka
full_name: Fukuda, Yutaka
last_name: Fukuda
- first_name: Shigeru
full_name: Yokoyama, Shigeru
last_name: Yokoyama
citation:
ama: Higashida H, Zhang J, Mochida S, et al. Subtype-specific coupling with ADP-ribosyl
cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion
and NG108-15 cells. Journal of Neurochemistry. 2003;85(5):1148-1158. doi:10.1046/j.1471-4159.2003.01751.x
apa: Higashida, H., Zhang, J., Mochida, S., Chen, X., Shin, Y., Noda, M., … Yokoyama,
S. (2003). Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic
glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Journal of Neurochemistry. Wiley-Blackwell. https://doi.org/10.1046/j.1471-4159.2003.01751.x
chicago: Higashida, Haruhiro, Jia Zhang, Sumiko Mochida, Xiao Chen, Yeonsook Shin,
Mami Noda, Kazi Hossain, et al. “Subtype-Specific Coupling with ADP-Ribosyl Cyclase
of Metabotropic Glutamate Receptors in Retina, Cervical Superior Ganglion and
NG108-15 Cells.” Journal of Neurochemistry. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1471-4159.2003.01751.x.
ieee: H. Higashida et al., “Subtype-specific coupling with ADP-ribosyl cyclase
of metabotropic glutamate receptors in retina, cervical superior ganglion and
NG108-15 cells,” Journal of Neurochemistry, vol. 85, no. 5. Wiley-Blackwell,
pp. 1148–1158, 2003.
ista: Higashida H, Zhang J, Mochida S, Chen X, Shin Y, Noda M, Hossain K, Hoshi
N, Hashii M, Shigemoto R, Nakanishi S, Fukuda Y, Yokoyama S. 2003. Subtype-specific
coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina,
cervical superior ganglion and NG108-15 cells. Journal of Neurochemistry. 85(5),
1148–1158.
mla: Higashida, Haruhiro, et al. “Subtype-Specific Coupling with ADP-Ribosyl Cyclase
of Metabotropic Glutamate Receptors in Retina, Cervical Superior Ganglion and
NG108-15 Cells.” Journal of Neurochemistry, vol. 85, no. 5, Wiley-Blackwell,
2003, pp. 1148–58, doi:10.1046/j.1471-4159.2003.01751.x.
short: H. Higashida, J. Zhang, S. Mochida, X. Chen, Y. Shin, M. Noda, K. Hossain,
N. Hoshi, M. Hashii, R. Shigemoto, S. Nakanishi, Y. Fukuda, S. Yokoyama, Journal
of Neurochemistry 85 (2003) 1148–1158.
date_created: 2018-12-11T11:58:46Z
date_published: 2003-06-01T00:00:00Z
date_updated: 2026-05-22T11:05:45Z
day: '01'
doi: 10.1046/j.1471-4159.2003.01751.x
extern: '1'
external_id:
pmid:
- '12753074'
intvolume: ' 85'
issue: '5'
language:
- iso: eng
month: '06'
oa_version: None
page: 1148 - 1158
pmid: 1
publication: Journal of Neurochemistry
publication_identifier:
eissn:
- 1471-4159
issn:
- 0022-3042
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4268'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate
receptors in retina, cervical superior ganglion and NG108-15 cells
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 85
year: '2003'
...
---
OA_type: closed access
_id: '2632'
abstract:
- lang: eng
text: In many brain regions, hyperpolarization-activated cationic currents (Ih)
are involved in the generation of rhythmic activities, but the role of Ih in olfactory
oscillations remains unclear. Knowledge of the cellular and subcellular distributions
of hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) subunits
is necessary for understanding the role of Ih in olfactory network activities.
Using light microscopic immunocytochemistry, we demonstrate strong HCN1 labelling
of the glomerular layer and moderate staining of granule cell, internal and external
plexiform layers of the rat main olfactory bulb. In the glomerular layer, among
many unlabelled neurons, two distinct subpopulations of juxtaglomerular cells
are labelled. Approximately 10% of the juxtaglomerular cells strongly express
HCN1. These small diameter cells are immunoreactive for GABA and comprise a subpopulation
of periglomerular cells. An additional subset of juxtaglomerular cells (≈ 1%)
expresses low levels of HCN1. They are large in diameter, GABA immunonegative
but immunopositive for vesicular glutamate transporter 2, characterizing them
as external tufted cells. Quantitative immunogold localization revealed that the
somatic plasma membranes of periglomerular cells contain approximately four times
more HCN1 labelling than those of external tufted cells. Unlike in cortical pyramidal
cells, immunogold density for HCN1 does not significantly differ in somatic and
dendritic plasma membranes of external tufted cells, indicating that post-synaptic
potentials arriving at proximal and distal dendrites are modulated by the same
density of I h. Our results demonstrate a cell type-dependent expression of HCN1
in the olfactory bulb and predict a differential contribution of distinct juxtaglomerular
cell types to network oscillations.
article_processing_charge: No
article_type: original
author:
- first_name: Noémi
full_name: Holderith, Noémi
last_name: Holderith
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Zoltán
full_name: Nusser, Zoltán
last_name: Nusser
citation:
ama: Holderith N, Shigemoto R, Nusser Z. Cell type-dependent expression of HCN1
in the main olfactory bulb. European Journal of Neuroscience. 2003;18(2):344-354.
doi:10.1046/j.1460-9568.2003.02756.x
apa: Holderith, N., Shigemoto, R., & Nusser, Z. (2003). Cell type-dependent
expression of HCN1 in the main olfactory bulb. European Journal of Neuroscience.
Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2003.02756.x
chicago: Holderith, Noémi, Ryuichi Shigemoto, and Zoltán Nusser. “Cell Type-Dependent
Expression of HCN1 in the Main Olfactory Bulb.” European Journal of Neuroscience.
Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1460-9568.2003.02756.x.
ieee: N. Holderith, R. Shigemoto, and Z. Nusser, “Cell type-dependent expression
of HCN1 in the main olfactory bulb,” European Journal of Neuroscience,
vol. 18, no. 2. Wiley-Blackwell, pp. 344–354, 2003.
ista: Holderith N, Shigemoto R, Nusser Z. 2003. Cell type-dependent expression of
HCN1 in the main olfactory bulb. European Journal of Neuroscience. 18(2), 344–354.
mla: Holderith, Noémi, et al. “Cell Type-Dependent Expression of HCN1 in the Main
Olfactory Bulb.” European Journal of Neuroscience, vol. 18, no. 2, Wiley-Blackwell,
2003, pp. 344–54, doi:10.1046/j.1460-9568.2003.02756.x.
short: N. Holderith, R. Shigemoto, Z. Nusser, European Journal of Neuroscience 18
(2003) 344–354.
date_created: 2018-12-11T11:58:47Z
date_published: 2003-07-01T00:00:00Z
date_updated: 2026-05-22T10:45:14Z
day: '01'
doi: 10.1046/j.1460-9568.2003.02756.x
extern: '1'
external_id:
pmid:
- '12887416'
intvolume: ' 18'
issue: '2'
language:
- iso: eng
month: '07'
oa_version: None
page: 344 - 354
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
eissn:
- 1460-9568
issn:
- 0953-816X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4266'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell type-dependent expression of HCN1 in the main olfactory bulb
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 18
year: '2003'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '2633'
abstract:
- lang: eng
text: The modulation of calcium channels by metabotropic glutamate receptors (mGluRs)
is a key event in the fine-tuning of neurotransmitter release. Here we report
that, in cerebrocortical nerve terminals of adult rats, the inhibition of glutamate
release is mediated by mGluR7. In this preparation, the major component of glutamate
release is supported by P/Q-type Ca2+ channels (72.7%). However, mGluR7 selectively
reduced the release component that is associated with N-type Ca2+ channels (29.9%).
Inhibition of P/Q channels by mGluR7 is not masked by the higher efficiency of
these channels in driving glutamate release when compared with N-type channels.
Thus, activation of mGluR7 failed to reduce the release associated with P/Q channels
when the extracellular calcium concentration, ([Ca2+]o), was reduced from 1.3
to 0.5 mM. Through Ca2+ imaging, we show that Ca2+ channels are distributed in
a heterogeneous manner in individual nerve terminals. Indeed, in this preparation,
nerve terminals were observed that contain N-type (31.1%; conotoxin GVIA-sensitive)
or P/Q-type (64.3%; agatoxin IVA-sensitive) channels or that were insensitive
to these two toxins (4.6%). Interestingly, the great majority of the responses
to L-AP4 (95.4%) were observed in nerve terminals containing N-type channels.
This specific co-localization of mGluR7 and N-type Ca2+-channels could explain
the failure of the receptor to inhibit the P/Q channel-associated release component
and also reveal the existence of specific targeting mechanisms to localize the
two proteins in the same nerve terminal subset.
article_processing_charge: No
article_type: original
author:
- first_name: Carmelo
full_name: Millán, Carmelo
last_name: Millán
- first_name: Enrique
full_name: Castro, Enrique
last_name: Castro
- first_name: Magdalena
full_name: Torres, Magdalena
last_name: Torres
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: José
full_name: Sánchez Prieto, José
last_name: Sánchez Prieto
citation:
ama: Millán C, Castro E, Torres M, Shigemoto R, Sánchez Prieto J. Co-expression
of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical
nerve terminals of adult rats. Journal of Biological Chemistry. 2003;278(26):23955-23962.
doi:10.1074/jbc.M211471200
apa: Millán, C., Castro, E., Torres, M., Shigemoto, R., & Sánchez Prieto, J.
(2003). Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels
in single cerebrocortical nerve terminals of adult rats. Journal of Biological
Chemistry. Elsevier. https://doi.org/10.1074/jbc.M211471200
chicago: Millán, Carmelo, Enrique Castro, Magdalena Torres, Ryuichi Shigemoto, and
José Sánchez Prieto. “Co-Expression of Metabotropic Glutamate Receptor 7 and N-Type
Ca2+ Channels in Single Cerebrocortical Nerve Terminals of Adult Rats.” Journal
of Biological Chemistry. Elsevier, 2003. https://doi.org/10.1074/jbc.M211471200.
ieee: C. Millán, E. Castro, M. Torres, R. Shigemoto, and J. Sánchez Prieto, “Co-expression
of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical
nerve terminals of adult rats,” Journal of Biological Chemistry, vol. 278,
no. 26. Elsevier, pp. 23955–23962, 2003.
ista: Millán C, Castro E, Torres M, Shigemoto R, Sánchez Prieto J. 2003. Co-expression
of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical
nerve terminals of adult rats. Journal of Biological Chemistry. 278(26), 23955–23962.
mla: Millán, Carmelo, et al. “Co-Expression of Metabotropic Glutamate Receptor 7
and N-Type Ca2+ Channels in Single Cerebrocortical Nerve Terminals of Adult Rats.”
Journal of Biological Chemistry, vol. 278, no. 26, Elsevier, 2003, pp.
23955–62, doi:10.1074/jbc.M211471200.
short: C. Millán, E. Castro, M. Torres, R. Shigemoto, J. Sánchez Prieto, Journal
of Biological Chemistry 278 (2003) 23955–23962.
date_created: 2018-12-11T11:58:47Z
date_published: 2003-07-27T00:00:00Z
date_updated: 2026-05-22T10:29:51Z
day: '27'
doi: 10.1074/jbc.M211471200
extern: '1'
external_id:
pmid:
- '12692128 '
intvolume: ' 278'
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1074/jbc.M211471200
month: '07'
oa: 1
oa_version: Published Version
page: 23955 - 23962
pmid: 1
publication: Journal of Biological Chemistry
publication_identifier:
eissn:
- 1083-351X
issn:
- 0021-9258
publication_status: published
publisher: Elsevier
publist_id: '4265'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels
in single cerebrocortical nerve terminals of adult rats
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 278
year: '2003'
...
---
OA_type: closed access
_id: '2634'
abstract:
- lang: eng
text: To better understand the role of neurotransmitter receptors in neuronal differentiation
and maturation a detailed knowledge of their identity, location and function in
the plasma membrane of specific neuronal populations during development is required.
Combining pre-embedding immunocytochemistry with cell tracking in embryonic brain
slice cultures we show that virtually all neurons (∼98%) migrating through the
lower intermediate zone (LIZ) on their way from the medial ganglionic eminence
to the cerebral cortex, express GABA BR1. Blockade of GABABRs with a specific
antagonist, CGP52432, resulted in a concentration-dependent accumulation of these
tangentially migrating neurons in the ventricular/subventricular zones (VZ/SVZ)
of the cortex and fewer cells were observed in the cortical plate/marginal zone
(CP/MZ) and LIZ. Moreover, they had significantly shorter leading processes compared
with similar migrating cells in control slices. Electrophysiological recording
in LIZ and CP cells revealed no direct effect of either CGP52432 or the GABABR
agonist, baclofen, on resting membrane properties suggesting that the effect of
CGP52432 on migration might be mediated through a metabotropic action or the regulation
of release of factors controlling migration. These results suggest that GABABRs
have an important modulatory role in the migration of cortical interneurons.
article_processing_charge: No
article_type: original
author:
- first_name: Guillermina
full_name: López Bendito, Guillermina
last_name: López Bendito
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Paul
full_name: Ganter, Paul
last_name: Ganter
- first_name: Ole
full_name: Paulsen, Ole
last_name: Paulsen
- first_name: Zoltán
full_name: Molnár, Zoltán
last_name: Molnár
citation:
ama: López Bendito G, Luján R, Shigemoto R, Ganter P, Paulsen O, Molnár Z. Blockade
of GABAB receptors alters the tangential migration of cortical neurons. Cerebral
Cortex. 2003;13(9):932-942. doi:10.1093/cercor/13.9.932
apa: López Bendito, G., Luján, R., Shigemoto, R., Ganter, P., Paulsen, O., &
Molnár, Z. (2003). Blockade of GABAB receptors alters the tangential migration
of cortical neurons. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/13.9.932
chicago: López Bendito, Guillermina, Rafael Luján, Ryuichi Shigemoto, Paul Ganter,
Ole Paulsen, and Zoltán Molnár. “Blockade of GABAB Receptors Alters the Tangential
Migration of Cortical Neurons.” Cerebral Cortex. Oxford University Press,
2003. https://doi.org/10.1093/cercor/13.9.932.
ieee: G. López Bendito, R. Luján, R. Shigemoto, P. Ganter, O. Paulsen, and Z. Molnár,
“Blockade of GABAB receptors alters the tangential migration of cortical neurons,”
Cerebral Cortex, vol. 13, no. 9. Oxford University Press, pp. 932–942,
2003.
ista: López Bendito G, Luján R, Shigemoto R, Ganter P, Paulsen O, Molnár Z. 2003.
Blockade of GABAB receptors alters the tangential migration of cortical neurons.
Cerebral Cortex. 13(9), 932–942.
mla: López Bendito, Guillermina, et al. “Blockade of GABAB Receptors Alters the
Tangential Migration of Cortical Neurons.” Cerebral Cortex, vol. 13, no.
9, Oxford University Press, 2003, pp. 932–42, doi:10.1093/cercor/13.9.932.
short: G. López Bendito, R. Luján, R. Shigemoto, P. Ganter, O. Paulsen, Z. Molnár,
Cerebral Cortex 13 (2003) 932–942.
date_created: 2018-12-11T11:58:47Z
date_published: 2003-09-01T00:00:00Z
date_updated: 2026-05-22T09:53:10Z
day: '01'
doi: 10.1093/cercor/13.9.932
extern: '1'
external_id:
pmid:
- '12902392'
intvolume: ' 13'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 932 - 942
pmid: 1
publication: Cerebral Cortex
publication_identifier:
eissn:
- 1460-2199
issn:
- 1047-3211
publication_status: published
publisher: Oxford University Press
publist_id: '4264'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Blockade of GABAB receptors alters the tangential migration of cortical neurons
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 13
year: '2003'
...
---
OA_type: closed access
_id: '2635'
abstract:
- lang: eng
text: Metabotropic GABAB receptors mediate slow inhibitory effects presynaptically
and postsynaptically. Using preembedding immunohistochemical methods combined
with quantitative analysis of GABAB receptor subunit immunoreactivity, this study
provides a detailed description of the cellular and subcellular localization of
GABAB1a/b and GABA B2 in the rat hippocampus. At the light microscopic level,
an overlapping distribution of GABAB1a/b and GABAB2 was revealed in the dendritic
layers of the hippocampus. In addition, expression of the GABAB1a/b subunit was
found in somata of CA1 pyramidal cells and of a subset of GABAergic interneurons.
At the electron microscopic level, immunoreactivity for both subunits was observed
on presynaptic and, more abundantly, on postsynaptic elements. Presynaptically,
subunits were mainly detected in the extrasynaptic membrane and occasionally over
the presynaptic membrane specialization of putative glutamatergic and, to a lesser
extent, GABAergic axon terminals. Postsynaptically, the majority of GABAB receptor
subunits were localized to the extrasynaptic plasma membrane of spines and dendritic
shafts of principal cells and shafts of interneuron dendrites. Quantitative analysis
revealed enrichment of GABAB1a/b around putative glutamatergic synapses on spines
and an even distribution on dendritic shafts of pyramidal cells contacted by GABAergic
boutons. The association of GABAB receptors with glutamatergic synapses at both
presynaptic and postsynaptic sides indicates their intimate involvement in the
modulation of glutamatergic neurotransmission. The dominant extrasynaptic localization
of GABAB receptor subunits suggests that their activation is dependent on spillover
of GABA requiring simultaneous activity of populations of GABAergic cells as it
occurs during population oscillations or epileptic seizures.
article_processing_charge: No
article_type: original
author:
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Carola
full_name: Haas, Carola
last_name: Haas
- first_name: Guillermina
full_name: López Bendito, Guillermina
last_name: López Bendito
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
citation:
ama: Kulik Á, Vida I, Luján R, et al. Subcellular Localization of Metabotropic GABAB
Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus. Journal of Neuroscience.
2003;23(35):11026-11035. doi:10.1523/JNEUROSCI.23-35-11026.2003
apa: Kulik, Á., Vida, I., Luján, R., Haas, C., López Bendito, G., Shigemoto, R.,
& Frotscher, M. (2003). Subcellular Localization of Metabotropic GABAB Receptor
Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.23-35-11026.2003
chicago: Kulik, Ákos, Imre Vida, Rafael Luján, Carola Haas, Guillermina López Bendito,
Ryuichi Shigemoto, and Michael Frotscher. “Subcellular Localization of Metabotropic
GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus.” Journal
of Neuroscience. Society for Neuroscience, 2003. https://doi.org/10.1523/JNEUROSCI.23-35-11026.2003.
ieee: Á. Kulik et al., “Subcellular Localization of Metabotropic GABAB Receptor
Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus,” Journal of Neuroscience,
vol. 23, no. 35. Society for Neuroscience, pp. 11026–11035, 2003.
ista: Kulik Á, Vida I, Luján R, Haas C, López Bendito G, Shigemoto R, Frotscher
M. 2003. Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b
and GABAB2 in the Rat Hippocampus. Journal of Neuroscience. 23(35), 11026–11035.
mla: Kulik, Ákos, et al. “Subcellular Localization of Metabotropic GABAB Receptor
Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus.” Journal of Neuroscience,
vol. 23, no. 35, Society for Neuroscience, 2003, pp. 11026–35, doi:10.1523/JNEUROSCI.23-35-11026.2003.
short: Á. Kulik, I. Vida, R. Luján, C. Haas, G. López Bendito, R. Shigemoto, M.
Frotscher, Journal of Neuroscience 23 (2003) 11026–11035.
date_created: 2018-12-11T11:58:47Z
date_published: 2003-12-03T00:00:00Z
date_updated: 2026-05-22T09:50:16Z
day: '03'
doi: 10.1523/JNEUROSCI.23-35-11026.2003
extern: '1'
external_id:
pmid:
- '14657159'
intvolume: ' 23'
issue: '35'
language:
- iso: eng
month: '12'
oa_version: None
page: 11026 - 11035
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
eissn:
- 1529-2401
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '4263'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b
and GABAB2 in the Rat Hippocampus
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 23
year: '2003'
...
---
OA_type: closed access
_id: '2637'
abstract:
- lang: eng
text: While the cholinergic depletion in Alzheimer's disease (AD) has been known
for some time, a definitive involvement of other neurotransmitter systems has
been somewhat more elusive. Our study demonstrates a clear involvement of both
glutamatergic and, to a lesser extent, GABAergic neurons in an early onset transgenic
mouse model of AD-like amyloid pathology. Immunohistochemical staining and subsequent
quantification has revealed a statistically significant increased density of glutamatergic
and GABAergic presynaptic boutons in both the plaque free and plaque adjacent
cortical neuropile areas of transgenic mice as compared to non-transgenic controls.
Furthermore, amyloid plaque size was shown to have a statistically significant
effect on the relative area occupied by dystrophic glutamatergic neurites in the
peri-plaque neuropile. These findings support our hypothesis that the amyloid
pathology progresses in a time and neurotransmitter specific manner, first in
the cholinergic system which appears to be most vulnerable, followed by the glutamatergic
presynaptic boutons and finally the somewhat more resilient GABAergic terminals.
article_processing_charge: No
article_type: original
author:
- first_name: Karen
full_name: Bell, Karen
last_name: Bell
- first_name: G J
full_name: De Kort, G J
last_name: De Kort
- first_name: S
full_name: Steggerda, S
last_name: Steggerda
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Alfredo
full_name: Ribeiro Da Silva, Alfredo
last_name: Ribeiro Da Silva
- first_name: Augusto
full_name: Cuello, Augusto
last_name: Cuello
citation:
ama: Bell K, De Kort GJ, Steggerda S, Shigemoto R, Ribeiro Da Silva A, Cuello A.
Structural involvement of the glutamatergic presynaptic boutons in a transgenic
mouse model expressing early onset amyloid pathology. Neuroscience Letters.
2003;353(2):143-147. doi:10.1016/j.neulet.2003.09.027
apa: Bell, K., De Kort, G. J., Steggerda, S., Shigemoto, R., Ribeiro Da Silva, A.,
& Cuello, A. (2003). Structural involvement of the glutamatergic presynaptic
boutons in a transgenic mouse model expressing early onset amyloid pathology.
Neuroscience Letters. Elsevier. https://doi.org/10.1016/j.neulet.2003.09.027
chicago: Bell, Karen, G J De Kort, S Steggerda, Ryuichi Shigemoto, Alfredo Ribeiro
Da Silva, and Augusto Cuello. “Structural Involvement of the Glutamatergic Presynaptic
Boutons in a Transgenic Mouse Model Expressing Early Onset Amyloid Pathology.”
Neuroscience Letters. Elsevier, 2003. https://doi.org/10.1016/j.neulet.2003.09.027.
ieee: K. Bell, G. J. De Kort, S. Steggerda, R. Shigemoto, A. Ribeiro Da Silva, and
A. Cuello, “Structural involvement of the glutamatergic presynaptic boutons in
a transgenic mouse model expressing early onset amyloid pathology,” Neuroscience
Letters, vol. 353, no. 2. Elsevier, pp. 143–147, 2003.
ista: Bell K, De Kort GJ, Steggerda S, Shigemoto R, Ribeiro Da Silva A, Cuello A.
2003. Structural involvement of the glutamatergic presynaptic boutons in a transgenic
mouse model expressing early onset amyloid pathology. Neuroscience Letters. 353(2),
143–147.
mla: Bell, Karen, et al. “Structural Involvement of the Glutamatergic Presynaptic
Boutons in a Transgenic Mouse Model Expressing Early Onset Amyloid Pathology.”
Neuroscience Letters, vol. 353, no. 2, Elsevier, 2003, pp. 143–47, doi:10.1016/j.neulet.2003.09.027.
short: K. Bell, G.J. De Kort, S. Steggerda, R. Shigemoto, A. Ribeiro Da Silva, A.
Cuello, Neuroscience Letters 353 (2003) 143–147.
date_created: 2018-12-11T11:58:48Z
date_published: 2003-12-19T00:00:00Z
date_updated: 2026-05-22T09:46:51Z
day: '19'
doi: 10.1016/j.neulet.2003.09.027
extern: '1'
external_id:
pmid:
- '14664921'
intvolume: ' 353'
issue: '2'
language:
- iso: eng
month: '12'
oa_version: None
page: 143 - 147
pmid: 1
publication: Neuroscience Letters
publication_identifier:
eissn:
- 1872-7972
issn:
- 0304-3940
publication_status: published
publisher: Elsevier
publist_id: '4262'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural involvement of the glutamatergic presynaptic boutons in a transgenic
mouse model expressing early onset amyloid pathology
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 353
year: '2003'
...
---
OA_type: free access
_id: '2784'
abstract:
- lang: eng
text: We report the results of an experimental study of magnetohydrodynamic damping
of sidewall convection in a rectangular enclosure filled with gallium. In particular
we investigate the suppression of convection when a steady magnetic field is applied
separately in each of the three principal directions of the flow. The strongest
damping of the steady flow is found for a vertical magnetic field, which is in
agreement with theory. However, we observe that the application of a field transverse
to the flow provides greater damping than a longitudinal one, which seems to contradict
available theory. We provide a possible resolution of this apparent dichotomy
in terms of the length scale of the experiment.
article_processing_charge: No
article_type: original
author:
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Anne
full_name: Juel, Anne
last_name: Juel
- first_name: Tom
full_name: Mullin, Tom
last_name: Mullin
citation:
ama: Hof B, Juel A, Mullin T. Magnetohydrodynamic damping of convective flows in
molten gallium. Journal of Fluid Mechanics. 2003;482:163-179. doi:10.1017/S0022112003004014
apa: Hof, B., Juel, A., & Mullin, T. (2003). Magnetohydrodynamic damping of
convective flows in molten gallium. Journal of Fluid Mechanics. Cambridge
University Press. https://doi.org/10.1017/S0022112003004014
chicago: Hof, Björn, Anne Juel, and Tom Mullin. “Magnetohydrodynamic Damping of
Convective Flows in Molten Gallium.” Journal of Fluid Mechanics. Cambridge
University Press, 2003. https://doi.org/10.1017/S0022112003004014.
ieee: B. Hof, A. Juel, and T. Mullin, “Magnetohydrodynamic damping of convective
flows in molten gallium,” Journal of Fluid Mechanics, vol. 482. Cambridge
University Press, pp. 163–179, 2003.
ista: Hof B, Juel A, Mullin T. 2003. Magnetohydrodynamic damping of convective flows
in molten gallium. Journal of Fluid Mechanics. 482, 163–179.
mla: Hof, Björn, et al. “Magnetohydrodynamic Damping of Convective Flows in Molten
Gallium.” Journal of Fluid Mechanics, vol. 482, Cambridge University Press,
2003, pp. 163–79, doi:10.1017/S0022112003004014.
short: B. Hof, A. Juel, T. Mullin, Journal of Fluid Mechanics 482 (2003) 163–179.
date_created: 2018-12-11T11:59:35Z
date_published: 2003-05-13T00:00:00Z
date_updated: 2026-05-22T09:44:10Z
day: '13'
doi: 10.1017/S0022112003004014
extern: '1'
intvolume: ' 482'
language:
- iso: eng
month: '05'
oa_version: None
page: 163 - 179
publication: Journal of Fluid Mechanics
publication_identifier:
eissn:
- 1469-7645
issn:
- 0022-1120
publication_status: published
publisher: Cambridge University Press
publist_id: '4105'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Magnetohydrodynamic damping of convective flows in molten gallium
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 482
year: '2003'
...
---
OA_place: repository
OA_type: green
_id: '2785'
abstract:
- lang: eng
text: "We report the results of an experimental investigation of the transition
to turbulence in a pipe over approximately an order of magnitude range in the
Reynolds number Re. A novel scaling law is uncovered using a systematic experimental
procedure which permits contact to be made with modern theoretical thinking. The
principal result we uncover is a scaling law which indicates that the amplitude
of perturbation required to cause transition scales as \U0001D442(Re−1)."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Anne
full_name: Juel, Anne
last_name: Juel
- first_name: Tom
full_name: Mullin, Tom
last_name: Mullin
citation:
ama: Hof B, Juel A, Mullin T. Scaling of the turbulence transition threshold in
a pipe. Physical Review Letters. 2003;91(24):244502/1-244502/4. doi:10.1103/PhysRevLett.91.244502
apa: Hof, B., Juel, A., & Mullin, T. (2003). Scaling of the turbulence transition
threshold in a pipe. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.91.244502
chicago: Hof, Björn, Anne Juel, and Tom Mullin. “Scaling of the Turbulence Transition
Threshold in a Pipe.” Physical Review Letters. American Physical Society,
2003. https://doi.org/10.1103/PhysRevLett.91.244502.
ieee: B. Hof, A. Juel, and T. Mullin, “Scaling of the turbulence transition threshold
in a pipe,” Physical Review Letters, vol. 91, no. 24. American Physical
Society, p. 244502/1-244502/4, 2003.
ista: Hof B, Juel A, Mullin T. 2003. Scaling of the turbulence transition threshold
in a pipe. Physical Review Letters. 91(24), 244502/1-244502/4.
mla: Hof, Björn, et al. “Scaling of the Turbulence Transition Threshold in a Pipe.”
Physical Review Letters, vol. 91, no. 24, American Physical Society, 2003,
p. 244502/1-244502/4, doi:10.1103/PhysRevLett.91.244502.
short: B. Hof, A. Juel, T. Mullin, Physical Review Letters 91 (2003) 244502/1-244502/4.
date_created: 2018-12-11T11:59:35Z
date_published: 2003-12-12T00:00:00Z
date_updated: 2026-05-22T09:38:23Z
day: '12'
doi: 10.1103/PhysRevLett.91.244502
extern: '1'
external_id:
arxiv:
- '0306684'
intvolume: ' 91'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.cond-mat/0306684'
month: '12'
oa: 1
oa_version: Preprint
page: 244502/1 - 244502/4
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
publist_id: '4104'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scaling of the turbulence transition threshold in a pipe
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 91
year: '2003'
...
---
_id: '2990'
abstract:
- lang: eng
text: Plant growth is marked by its adaptability to continuous changes in environment.
A regulated, differential distribution of auxin underlies many adaptation processes
including organogenesis, meristem patterning and tropisms. In executing its multiple
roles, auxin displays some characteristics of both a hormone and a morphogen.
Studies on auxin transport, as well as tracing the intracellular movement of its
molecular components, have suggested a possible scenario to explain how growth
plasticity is conferred at the cellular and molecular level. The plant perceives
stimuli and changes the subcellular position of auxin-transport components accordingly.
These changes modulate auxin fluxes, and the newly established auxin distribution
triggers the corresponding developmental response.
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Friml J. Auxin transport - Shaping the plant. Current Opinion in Plant Biology.
2003;6(1):7-12. doi:10.1016/S1369526602000031
apa: Friml, J. (2003). Auxin transport - Shaping the plant. Current Opinion in
Plant Biology. Elsevier. https://doi.org/10.1016/S1369526602000031
chicago: Friml, Jiří. “Auxin Transport - Shaping the Plant.” Current Opinion
in Plant Biology. Elsevier, 2003. https://doi.org/10.1016/S1369526602000031.
ieee: J. Friml, “Auxin transport - Shaping the plant,” Current Opinion in Plant
Biology, vol. 6, no. 1. Elsevier, pp. 7–12, 2003.
ista: Friml J. 2003. Auxin transport - Shaping the plant. Current Opinion in Plant
Biology. 6(1), 7–12.
mla: Friml, Jiří. “Auxin Transport - Shaping the Plant.” Current Opinion in Plant
Biology, vol. 6, no. 1, Elsevier, 2003, pp. 7–12, doi:10.1016/S1369526602000031.
short: J. Friml, Current Opinion in Plant Biology 6 (2003) 7–12.
date_created: 2018-12-11T12:00:43Z
date_published: 2003-02-01T00:00:00Z
date_updated: 2021-01-12T07:40:17Z
day: '01'
doi: 10.1016/S1369526602000031
extern: '1'
intvolume: ' 6'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 7 - 12
publication: Current Opinion in Plant Biology
publication_status: published
publisher: Elsevier
publist_id: '3711'
quality_controlled: '1'
status: public
title: Auxin transport - Shaping the plant
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2003'
...
---
OA_type: closed access
_id: '2992'
abstract:
- lang: eng
text: Plants have many polarized cell types, but relatively little is known about
the mechanisms that establish polarity. The orc mutant was identified originally
by defects in root patterning, and positional cloning revealed that the affected
gene encodes STEROL METHYLTRANSFERASE1, which is required for the appropriate
synthesis and composition of major membrane sterols. smt1orc mutants displayed
several conspicuous cell polarity defects. Columella root cap cells revealed perturbed
polar positioning of different organelles, and in the smt1orc root epidermis,
polar initiation of root hairs was more randomized. Polar auxin transport and
expression of the auxin reporter DR5-β-glucuronidase were aberrant in smt1orc.
Patterning defects in smt1orc resembled those observed in mutants of the PIN gene
family of putative auxin efflux transporters. Consistently, the membrane localization
of the PIN1 and PIN3 proteins was disturbed in smt1orc, whereas polar positioning
of the influx carrier AUX1 appeared normal. Our results suggest that balanced
sterol composition is a major requirement for cell polarity and auxin efflux in
Arabidopsis.
article_processing_charge: No
article_type: original
author:
- first_name: Viola
full_name: Willemsen, Viola
last_name: Willemsen
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Markus
full_name: Grebe, Markus
last_name: Grebe
- first_name: Albert
full_name: Van Den Toorn, Albert
last_name: Van Den Toorn
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
citation:
ama: Willemsen V, Friml J, Grebe M, Van Den Toorn A, Palme K, Scheres B. Cell polarity
and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function.
Plant Cell. 2003;15(3):612-625. doi:10.1105/tpc.008433
apa: Willemsen, V., Friml, J., Grebe, M., Van Den Toorn, A., Palme, K., & Scheres,
B. (2003). Cell polarity and PIN protein positioning in Arabidopsis require STEROL
METHYLTRANSFERASE1 function. Plant Cell. American Society of Plant Biologists.
https://doi.org/10.1105/tpc.008433
chicago: Willemsen, Viola, Jiří Friml, Markus Grebe, Albert Van Den Toorn, Klaus
Palme, and Ben Scheres. “Cell Polarity and PIN Protein Positioning in Arabidopsis
Require STEROL METHYLTRANSFERASE1 Function.” Plant Cell. American Society
of Plant Biologists, 2003. https://doi.org/10.1105/tpc.008433.
ieee: V. Willemsen, J. Friml, M. Grebe, A. Van Den Toorn, K. Palme, and B. Scheres,
“Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1
function,” Plant Cell, vol. 15, no. 3. American Society of Plant Biologists,
pp. 612–625, 2003.
ista: Willemsen V, Friml J, Grebe M, Van Den Toorn A, Palme K, Scheres B. 2003.
Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1
function. Plant Cell. 15(3), 612–625.
mla: Willemsen, Viola, et al. “Cell Polarity and PIN Protein Positioning in Arabidopsis
Require STEROL METHYLTRANSFERASE1 Function.” Plant Cell, vol. 15, no. 3,
American Society of Plant Biologists, 2003, pp. 612–25, doi:10.1105/tpc.008433.
short: V. Willemsen, J. Friml, M. Grebe, A. Van Den Toorn, K. Palme, B. Scheres,
Plant Cell 15 (2003) 612–625.
date_created: 2018-12-11T12:00:44Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2026-05-22T09:04:01Z
day: '01'
doi: 10.1105/tpc.008433
extern: '1'
external_id:
pmid:
- '12615936'
intvolume: ' 15'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 612 - 625
pmid: 1
publication: Plant Cell
publication_identifier:
eissn:
- 1532-298X
issn:
- 1040-4651
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1
function
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 15
year: '2003'
...
---
OA_type: closed access
_id: '2993'
abstract:
- lang: eng
text: Plant biology is currently experiencing a growing demand for easy and reliable
mRNA and protein localisation techniques. Here, we present novel whole mount in
situ hybridisation and immunolocalisation protocols, suitable to localise mRNAs
and proteins in Arabidopsis seedlings. We demonstrate that these methods can be
used in different organs of Arabidopsis seedlings as well as in other plant species.
In order to achieve better reproducibility and higher throughput, we modified
these protocols for automation to be performed by a liquid handling robot. In
addition, we show that other procedures such as reporter enzyme assays and tissue
clearing can be similarly automated. We present examples of application of our
protocols including mRNA localisation and proteins and epitope tag (co)localisations
which demonstrate that these methods provide reliable and versatile tools for
expression, localisation and anatomical studies in plants.
article_processing_charge: No
article_type: original
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Ulrike
full_name: Mayer, Ulrike
last_name: Mayer
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Gerhard
full_name: Muster, Gerhard
last_name: Muster
citation:
ama: Friml J, Benková E, Mayer U, Palme K, Muster G. Automated whole mount localisation
techniques for plant seedlings. Plant Journal. 2003;34(1):115-124. doi:10.1046/j.1365-313X.2003.01705.x
apa: Friml, J., Benková, E., Mayer, U., Palme, K., & Muster, G. (2003). Automated
whole mount localisation techniques for plant seedlings. Plant Journal.
Wiley. https://doi.org/10.1046/j.1365-313X.2003.01705.x
chicago: Friml, Jiří, Eva Benková, Ulrike Mayer, Klaus Palme, and Gerhard Muster.
“Automated Whole Mount Localisation Techniques for Plant Seedlings.” Plant
Journal. Wiley, 2003. https://doi.org/10.1046/j.1365-313X.2003.01705.x.
ieee: J. Friml, E. Benková, U. Mayer, K. Palme, and G. Muster, “Automated whole
mount localisation techniques for plant seedlings,” Plant Journal, vol.
34, no. 1. Wiley, pp. 115–124, 2003.
ista: Friml J, Benková E, Mayer U, Palme K, Muster G. 2003. Automated whole mount
localisation techniques for plant seedlings. Plant Journal. 34(1), 115–124.
mla: Friml, Jiří, et al. “Automated Whole Mount Localisation Techniques for Plant
Seedlings.” Plant Journal, vol. 34, no. 1, Wiley, 2003, pp. 115–24, doi:10.1046/j.1365-313X.2003.01705.x.
short: J. Friml, E. Benková, U. Mayer, K. Palme, G. Muster, Plant Journal 34 (2003)
115–124.
date_created: 2018-12-11T12:00:44Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2026-05-22T09:01:28Z
day: '01'
doi: 10.1046/j.1365-313X.2003.01705.x
extern: '1'
external_id:
pmid:
- '12662314'
intvolume: ' 34'
issue: '1'
language:
- iso: eng
month: '04'
oa_version: None
page: 115 - 124
pmid: 1
publication: Plant Journal
publication_identifier:
eissn:
- 1365-313X
issn:
- 0960-7412
publication_status: published
publisher: Wiley
publist_id: '3709'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Automated whole mount localisation techniques for plant seedlings
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 34
year: '2003'
...
---
OA_type: closed access
_id: '2994'
abstract:
- lang: eng
text: The regular arrangement of leaves around a plant's stem, called phyllotaxis,
has for centuries attracted the attention of philosophers, mathematicians and
natural scientists; however, to date, studies of phyllotaxis have been largely
theoretical. Leaves and flowers are formed from the shoot apical meristem, triggered
by the plant hormone auxin. Auxin is transported through plant tissues by specific
cellular influx and efflux carrier proteins. Here we show that proteins involved
in auxin transport regulate phyllotaxis. Our data indicate that auxin is transported
upwards into the meristem through the epidermis and the outermost meristem cell
layer. Existing leaf primordia act as sinks, redistributing auxin and creating
its heterogeneous distribution in the meristem. Auxin accumulation occurs only
at certain minimal distances from existing primordia, defining the position of
future primordia. This model for phyllotaxis accounts for its reiterative nature,
as well as its regularity and stability.
article_processing_charge: No
article_type: original
author:
- first_name: Didier
full_name: Reinhardt, Didier
last_name: Reinhardt
- first_name: Eva
full_name: Pesce, Eva
last_name: Pesce
- first_name: Pia
full_name: Stieger, Pia
last_name: Stieger
- first_name: Therese
full_name: Mandel, Therese
last_name: Mandel
- first_name: Kurt
full_name: Baltensperger, Kurt
last_name: Baltensperger
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Jan
full_name: Traas, Jan
last_name: Traas
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Cris
full_name: Kuhlemeier, Cris
last_name: Kuhlemeier
citation:
ama: Reinhardt D, Pesce E, Stieger P, et al. Regulation of phyllotaxis by polar
auxin transport. Nature. 2003;426:255-260. doi:10.1038/nature02081
apa: Reinhardt, D., Pesce, E., Stieger, P., Mandel, T., Baltensperger, K., Bennett,
M., … Kuhlemeier, C. (2003). Regulation of phyllotaxis by polar auxin transport.
Nature. Springer Nature. https://doi.org/10.1038/nature02081
chicago: Reinhardt, Didier, Eva Pesce, Pia Stieger, Therese Mandel, Kurt Baltensperger,
Malcolm Bennett, Jan Traas, Jiří Friml, and Cris Kuhlemeier. “Regulation of Phyllotaxis
by Polar Auxin Transport.” Nature. Springer Nature, 2003. https://doi.org/10.1038/nature02081.
ieee: D. Reinhardt et al., “Regulation of phyllotaxis by polar auxin transport,”
Nature, vol. 426. Springer Nature, pp. 255–260, 2003.
ista: Reinhardt D, Pesce E, Stieger P, Mandel T, Baltensperger K, Bennett M, Traas
J, Friml J, Kuhlemeier C. 2003. Regulation of phyllotaxis by polar auxin transport.
Nature. 426, 255–260.
mla: Reinhardt, Didier, et al. “Regulation of Phyllotaxis by Polar Auxin Transport.”
Nature, vol. 426, Springer Nature, 2003, pp. 255–60, doi:10.1038/nature02081.
short: D. Reinhardt, E. Pesce, P. Stieger, T. Mandel, K. Baltensperger, M. Bennett,
J. Traas, J. Friml, C. Kuhlemeier, Nature 426 (2003) 255–260.
date_created: 2018-12-11T12:00:45Z
date_published: 2003-11-20T00:00:00Z
date_updated: 2026-05-22T08:55:25Z
day: '20'
doi: 10.1038/nature02081
extern: '1'
external_id:
pmid:
- '14628043'
intvolume: ' 426'
language:
- iso: eng
month: '11'
oa_version: None
page: 255 - 260
pmid: 1
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
publist_id: '3707'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of phyllotaxis by polar auxin transport
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 426
year: '2003'
...
---
_id: '2995'
abstract:
- lang: eng
text: "Axis formation occurs in plants, as in animals, during early embryogenesis.
However, the underlying mechanism is not known. Here we show that the first manifestation
of the apical-basal axis in plants, the asymmetric division of the zygote, produces
a basal cell that transports and an apical cell that responds to the signalling
molecule auxin. This apical-basal auxin activity gradient triggers the specification
of apical embryo structures and is actively maintained by a novel component of
auxin efflux, PIN7, which is located apically in the basal cell. Later, the developmentally
regulated reversal of PIN7 and onset of PIN1 polar localization reorganize the
auxin gradient for specification of the basal root pole. An analysis of pin quadruple
mutants identifies PIN-dependent transport as an essential part of the mechanism
for embryo axis formation. Our results indicate how the establishment of cell
polarity, polar auxin efflux and local auxin response result in apical-basal axis
formation of the embryo, and thus determine the axiality of the adult plant.\r\n"
article_processing_charge: No
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Anne
full_name: Vieten, Anne
last_name: Vieten
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Heinz
full_name: Schwarz, Heinz
last_name: Schwarz
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Remko
full_name: Offringa, Remko
last_name: Offringa
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
citation:
ama: Friml J, Vieten A, Sauer M, et al. Efflux dependent auxin gradients establish
the apical basal axis of Arabidopsis. Nature. 2003;426:147-153. doi:10.1038/nature02085
apa: Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., … Jürgens,
G. (2003). Efflux dependent auxin gradients establish the apical basal axis of
Arabidopsis. Nature. Springer Nature. https://doi.org/10.1038/nature02085
chicago: Friml, Jiří, Anne Vieten, Michael Sauer, Dolf Weijers, Heinz Schwarz, Thorsten
Hamann, Remko Offringa, and Gerd Jürgens. “Efflux Dependent Auxin Gradients Establish
the Apical Basal Axis of Arabidopsis.” Nature. Springer Nature, 2003. https://doi.org/10.1038/nature02085.
ieee: J. Friml et al., “Efflux dependent auxin gradients establish the apical
basal axis of Arabidopsis,” Nature, vol. 426. Springer Nature, pp. 147–153,
2003.
ista: Friml J, Vieten A, Sauer M, Weijers D, Schwarz H, Hamann T, Offringa R, Jürgens
G. 2003. Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis.
Nature. 426, 147–153.
mla: Friml, Jiří, et al. “Efflux Dependent Auxin Gradients Establish the Apical
Basal Axis of Arabidopsis.” Nature, vol. 426, Springer Nature, 2003, pp.
147–53, doi:10.1038/nature02085.
short: J. Friml, A. Vieten, M. Sauer, D. Weijers, H. Schwarz, T. Hamann, R. Offringa,
G. Jürgens, Nature 426 (2003) 147–153.
date_created: 2018-12-11T12:00:45Z
date_published: 2003-11-13T00:00:00Z
date_updated: 2026-05-22T08:58:10Z
day: '13'
doi: 10.1038/nature02085
extern: '1'
external_id:
pmid:
- '14614497 '
intvolume: ' 426'
language:
- iso: eng
month: '11'
oa_version: None
page: 147 - 153
pmid: 1
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
publist_id: '3708'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 426
year: '2003'
...
---
OA_place: publisher
OA_type: free access
_id: '2996'
abstract:
- lang: eng
text: "Plants, compared to animals, exhibit an amazing adaptability and plasticity
in their development. This is largely dependent on the ability of plants to form
new organs, such as lateral roots, leaves, and flowers during postembryonic development.
Organ primordia develop from founder cell populations into organs by coordinated
cell division and differentiation. Here, we show that organ formation in Arabidopsis
involves dynamic gradients of the signaling molecule auxin with maxima at the
primordia tips. These gradients are mediated by cellular efflux requiring asymmetrically
localized PIN proteins, which represent a functionally redundant network for auxin
distribution in both aerial and underground organs. PIN1 polar localization undergoes
a dynamic rearrangement, which correlates with establishment of auxin gradients
and primordium development. Our results suggest that PIN-dependent, local auxin
gradients represent a common module for formation of all plant organs, regardless
of their mature morphology or developmental origin.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Marta
full_name: Michniewicz, Marta
last_name: Michniewicz
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Thomas
full_name: Teichmann, Thomas
last_name: Teichmann
- first_name: Daniela
full_name: Seifertová, Daniela
last_name: Seifertová
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Benková E, Michniewicz M, Sauer M, et al. Local, efflux-dependent auxin gradients
as a common module for plant organ formation. Cell. 2003;115(5):591-602.
doi:10.1016/S0092-8674(03)00924-3
apa: Benková, E., Michniewicz, M., Sauer, M., Teichmann, T., Seifertová, D., Jürgens,
G., & Friml, J. (2003). Local, efflux-dependent auxin gradients as a common
module for plant organ formation. Cell. Cell Press. https://doi.org/10.1016/S0092-8674(03)00924-3
chicago: Benková, Eva, Marta Michniewicz, Michael Sauer, Thomas Teichmann, Daniela
Seifertová, Gerd Jürgens, and Jiří Friml. “Local, Efflux-Dependent Auxin Gradients
as a Common Module for Plant Organ Formation.” Cell. Cell Press, 2003.
https://doi.org/10.1016/S0092-8674(03)00924-3.
ieee: E. Benková et al., “Local, efflux-dependent auxin gradients as a common
module for plant organ formation,” Cell, vol. 115, no. 5. Cell Press, pp.
591–602, 2003.
ista: Benková E, Michniewicz M, Sauer M, Teichmann T, Seifertová D, Jürgens G, Friml
J. 2003. Local, efflux-dependent auxin gradients as a common module for plant
organ formation. Cell. 115(5), 591–602.
mla: Benková, Eva, et al. “Local, Efflux-Dependent Auxin Gradients as a Common Module
for Plant Organ Formation.” Cell, vol. 115, no. 5, Cell Press, 2003, pp.
591–602, doi:10.1016/S0092-8674(03)00924-3.
short: E. Benková, M. Michniewicz, M. Sauer, T. Teichmann, D. Seifertová, G. Jürgens,
J. Friml, Cell 115 (2003) 591–602.
date_created: 2018-12-11T12:00:46Z
date_published: 2003-11-26T00:00:00Z
date_updated: 2026-05-22T08:47:43Z
day: '26'
doi: 10.1016/S0092-8674(03)00924-3
extern: '1'
external_id:
pmid:
- '14651850'
intvolume: ' 115'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/S0092-8674(03)00924-3
month: '11'
oa: 1
oa_version: Published Version
page: 591 - 602
pmid: 1
publication: Cell
publication_identifier:
eissn:
- 1097-4172
issn:
- 0092-8674
publication_status: published
publisher: Cell Press
publist_id: '3706'
quality_controlled: '1'
status: public
title: Local, efflux-dependent auxin gradients as a common module for plant organ
formation
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 115
year: '2003'
...
---
_id: '13436'
abstract:
- lang: eng
text: Cross-metathesis reactions of α,β-unsaturated sulfones and sulfoxides in the
presence of molybdenum and ruthenium pre-catalysts were tested. A selective metahesis
reaction was achieved between functionalized terminal olefins and vinyl sulfones
by using the ‘second generation’ ruthenium catalysts 1c–h while the highly active
Schrock catalyst 1b was found to be functional group incompatible with vinyl sulfones.
The cross-metathesis products were isolated in good yields with an excellent (E)-selectivity.
Both the molybdenum and ruthenium-based complexes were, however, incompatible
with α,β- and β,γ-unsaturated sulfoxides.
article_processing_charge: No
article_type: original
author:
- first_name: Anna
full_name: Michrowska, Anna
last_name: Michrowska
- first_name: Michał
full_name: Bieniek, Michał
last_name: Bieniek
- first_name: Mikhail
full_name: Kim, Mikhail
last_name: Kim
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Karol
full_name: Grela, Karol
last_name: Grela
citation:
ama: Michrowska A, Bieniek M, Kim M, Klajn R, Grela K. Cross-metathesis reaction
of vinyl sulfones and sulfoxides. Tetrahedron. 2003;59(25):4525-4531. doi:10.1016/s0040-4020(03)00682-3
apa: Michrowska, A., Bieniek, M., Kim, M., Klajn, R., & Grela, K. (2003). Cross-metathesis
reaction of vinyl sulfones and sulfoxides. Tetrahedron. Elsevier. https://doi.org/10.1016/s0040-4020(03)00682-3
chicago: Michrowska, Anna, Michał Bieniek, Mikhail Kim, Rafal Klajn, and Karol Grela.
“Cross-Metathesis Reaction of Vinyl Sulfones and Sulfoxides.” Tetrahedron.
Elsevier, 2003. https://doi.org/10.1016/s0040-4020(03)00682-3.
ieee: A. Michrowska, M. Bieniek, M. Kim, R. Klajn, and K. Grela, “Cross-metathesis
reaction of vinyl sulfones and sulfoxides,” Tetrahedron, vol. 59, no. 25.
Elsevier, pp. 4525–4531, 2003.
ista: Michrowska A, Bieniek M, Kim M, Klajn R, Grela K. 2003. Cross-metathesis reaction
of vinyl sulfones and sulfoxides. Tetrahedron. 59(25), 4525–4531.
mla: Michrowska, Anna, et al. “Cross-Metathesis Reaction of Vinyl Sulfones and Sulfoxides.”
Tetrahedron, vol. 59, no. 25, Elsevier, 2003, pp. 4525–31, doi:10.1016/s0040-4020(03)00682-3.
short: A. Michrowska, M. Bieniek, M. Kim, R. Klajn, K. Grela, Tetrahedron 59 (2003)
4525–4531.
date_created: 2023-08-01T10:39:34Z
date_published: 2003-06-16T00:00:00Z
date_updated: 2023-08-08T12:44:17Z
day: '16'
doi: 10.1016/s0040-4020(03)00682-3
extern: '1'
intvolume: ' 59'
issue: '25'
keyword:
- Organic Chemistry
- Drug Discovery
- Biochemistry
language:
- iso: eng
month: '06'
oa_version: None
page: 4525-4531
publication: Tetrahedron
publication_identifier:
eissn:
- 1464-5416
issn:
- 0040-4020
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cross-metathesis reaction of vinyl sulfones and sulfoxides
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 59
year: '2003'
...
---
OA_place: repository
OA_type: green
_id: '1457'
abstract:
- lang: eng
text: 'Among the major mathematical approaches to mirror symmetry are those of Batyrev-Borisov
and Stromdnger-Yau-Zaslow (SYZ). The first is explicit and amenable to computation
but is not clearly related to the physical motivation; the second is the opposite.
Furthermore, it is far from obvious that mirror partners in one sense will also
be mirror partners in the other. This paper concerns a class of examples that
can be shown to satisfy the requirements of SYZ, but whose Hodge numbers are also
equal. This provides significant evidence in support of SYZ. Moreover, the examples
are of great interest in their own right: they are spaces of flat SLr-connections
on a smooth curve. The mirror is the corresponding space for the Langlands dual
group PGLr. These examples therefore throw a bridge from mirror symmetry to the
duality theory of Lie groups and, more broadly, to the geometric Langlands program.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Tamas
full_name: Hausel, Tamas
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
orcid: 0000-0002-9582-2634
- first_name: Michael
full_name: Thaddeus, Michael
last_name: Thaddeus
citation:
ama: Hausel T, Thaddeus M. Mirror symmetry, langlands duality, and the Hitchin system.
Inventiones Mathematicae. 2003;153:197-229. doi:10.1007/s00222-003-0286-7
apa: Hausel, T., & Thaddeus, M. (2003). Mirror symmetry, langlands duality,
and the Hitchin system. Inventiones Mathematicae. Springer Nature. https://doi.org/10.1007/s00222-003-0286-7
chicago: Hausel, Tamás, and Michael Thaddeus. “Mirror Symmetry, Langlands Duality,
and the Hitchin System.” Inventiones Mathematicae. Springer Nature, 2003.
https://doi.org/10.1007/s00222-003-0286-7.
ieee: T. Hausel and M. Thaddeus, “Mirror symmetry, langlands duality, and the Hitchin
system,” Inventiones Mathematicae, vol. 153. Springer Nature, pp. 197–229,
2003.
ista: Hausel T, Thaddeus M. 2003. Mirror symmetry, langlands duality, and the Hitchin
system. Inventiones Mathematicae. 153, 197–229.
mla: Hausel, Tamás, and Michael Thaddeus. “Mirror Symmetry, Langlands Duality, and
the Hitchin System.” Inventiones Mathematicae, vol. 153, Springer Nature,
2003, pp. 197–229, doi:10.1007/s00222-003-0286-7.
short: T. Hausel, M. Thaddeus, Inventiones Mathematicae 153 (2003) 197–229.
date_created: 2018-12-11T11:52:08Z
date_published: 2003-07-01T00:00:00Z
date_updated: 2026-05-28T11:54:13Z
day: '01'
doi: 10.1007/s00222-003-0286-7
extern: '1'
external_id:
arxiv:
- '0205236'
intvolume: ' 153'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.math/0205236'
month: '07'
oa: 1
oa_version: Preprint
page: 197 - 229
publication: Inventiones Mathematicae
publication_identifier:
eissn:
- 1432-1297
issn:
- 0020-9910
publication_status: published
publisher: Springer Nature
publist_id: '5738'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mirror symmetry, langlands duality, and the Hitchin system
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 153
year: '2003'
...
---
OA_place: repository
OA_type: green
_id: '1459'
abstract:
- lang: eng
text: 'In this paper we explicitly calculate the analogue of the ''t Hooft SU (2)
Yang-Mills instantons on Gibbons-Hawking multi-centered gravitational instantons,
which come in two parallel families: the multi-Eguchi-Hanson, or Ak ALE gravitational
instantons and the multi-Taub-NUT spaces, or Ak ALF gravitational instantons.
We calculate their energy and find the reducible ones. Following Kronheimer we
also exploit the U(1) invariance of our solutions and study the corresponding
explicit singular SU (2) magnetic monopole solutions of the Bogomolny equations
on flat ℝ3.'
acknowledgement: We would like to acknowledge the financial support by Prof. P. Major
(R ́ enyi Institute, Hungary) from his OTKA grant No. T26176 and of the Miller Institute
for Basic Research in Science at UC Berkeley.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Gábor
full_name: Etesi, Gábor
last_name: Etesi
- first_name: Tamas
full_name: Hausel, Tamas
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
orcid: 0000-0002-9582-2634
citation:
ama: Etesi G, Hausel T. On Yang-Mills instantons over multi-centered gravitational
instantons. Communications in Mathematical Physics. 2003;235:275-288. doi:10.1007/s00220-003-0806-8
apa: Etesi, G., & Hausel, T. (2003). On Yang-Mills instantons over multi-centered
gravitational instantons. Communications in Mathematical Physics. Springer
Nature. https://doi.org/10.1007/s00220-003-0806-8
chicago: Etesi, Gábor, and Tamás Hausel. “On Yang-Mills Instantons over Multi-Centered
Gravitational Instantons.” Communications in Mathematical Physics. Springer
Nature, 2003. https://doi.org/10.1007/s00220-003-0806-8.
ieee: G. Etesi and T. Hausel, “On Yang-Mills instantons over multi-centered gravitational
instantons,” Communications in Mathematical Physics, vol. 235. Springer
Nature, pp. 275–288, 2003.
ista: Etesi G, Hausel T. 2003. On Yang-Mills instantons over multi-centered gravitational
instantons. Communications in Mathematical Physics. 235, 275–288.
mla: Etesi, Gábor, and Tamás Hausel. “On Yang-Mills Instantons over Multi-Centered
Gravitational Instantons.” Communications in Mathematical Physics, vol.
235, Springer Nature, 2003, pp. 275–88, doi:10.1007/s00220-003-0806-8.
short: G. Etesi, T. Hausel, Communications in Mathematical Physics 235 (2003) 275–288.
date_created: 2018-12-11T11:52:09Z
date_published: 2003-04-01T00:00:00Z
date_updated: 2026-05-28T12:12:13Z
day: '01'
doi: 10.1007/s00220-003-0806-8
extern: '1'
external_id:
arxiv:
- '0207196'
intvolume: ' 235'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.hep-th/0207196'
month: '04'
oa: 1
oa_version: Preprint
page: 275 - 288
publication: Communications in Mathematical Physics
publication_identifier:
eissn:
- 1432-0916
issn:
- 0010-3616
publication_status: published
publisher: Springer Nature
publist_id: '5740'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On Yang-Mills instantons over multi-centered gravitational instantons
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 235
year: '2003'
...
---
_id: '166'
abstract:
- lang: eng
text: For any number field k, upper bounds are established for the number of k-rational
points of bounded height on non-singular del Pezzo surfaces defined over k, which
are equipped with suitable conic bundle structures over k.
alternative_title:
- Bonner mathematische Schriften
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: M
full_name: Swarbick Jones, M
last_name: Swarbick Jones
citation:
ama: Browning TD, Swarbick Jones M. Counting rational points on del Pezzo surfaces
of degree 5. Proceedings of the Bonn session in analytic number theory and
diophantine equations. 2003;360.
apa: Browning, T. D., & Swarbick Jones, M. (2003). Counting rational points
on del Pezzo surfaces of degree 5. Proceedings of the Bonn Session in Analytic
Number Theory and Diophantine Equations. Mathematisches Institut der Universität
Bonn.
chicago: Browning, Timothy D, and M Swarbick Jones. “Counting Rational Points on
Del Pezzo Surfaces of Degree 5.” Proceedings of the Bonn Session in Analytic
Number Theory and Diophantine Equations. Mathematisches Institut der Universität
Bonn, 2003.
ieee: T. D. Browning and M. Swarbick Jones, “Counting rational points on del Pezzo
surfaces of degree 5,” Proceedings of the Bonn session in analytic number theory
and diophantine equations, vol. 360. Mathematisches Institut der Universität
Bonn, 2003.
ista: Browning TD, Swarbick Jones M. 2003. Counting rational points on del Pezzo
surfaces of degree 5. Proceedings of the Bonn session in analytic number theory
and diophantine equations. 360.
mla: Browning, Timothy D., and M. Swarbick Jones. “Counting Rational Points on Del
Pezzo Surfaces of Degree 5.” Proceedings of the Bonn Session in Analytic Number
Theory and Diophantine Equations, vol. 360, Mathematisches Institut der Universität
Bonn, 2003.
short: T.D. Browning, M. Swarbick Jones, Proceedings of the Bonn Session in Analytic
Number Theory and Diophantine Equations 360 (2003).
date_created: 2018-12-11T11:44:58Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:20Z
day: '01'
extern: '1'
external_id:
arxiv:
- '1311.1665'
intvolume: ' 360'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1311.1665
month: '01'
oa: 1
oa_version: None
publication: Proceedings of the Bonn session in analytic number theory and diophantine
equations
publication_status: published
publisher: Mathematisches Institut der Universität Bonn
publist_id: '7755'
status: public
title: Counting rational points on del Pezzo surfaces of degree 5
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 360
year: '2003'
...