---
_id: '4561'
abstract:
- lang: eng
  text: 'We present a formalism for specifying component interfaces that expose component
    requirements on limited resources. The formalism permits an algorithmic check
    if two or more components, when put together, exceed the available resources.
    Moreover, the formalism can be used to compute the quantity of resources necessary
    for satisfying the requirements of a collection of components. The formalism can
    be instantiated in several ways. For example, several components may draw power
    from the same source. Then, the formalism supports compatibility checks such as:
    can two components, when put together, achieve their tasks without ever exceeding
    the available amount of peak power? or, can they achieve their tasks by using
    no more than the initially available amount of energy (i.e., power accumulated
    over time)? The corresponding quantitative questions that our algorithms answer
    are the following: what is the amount of peak power needed for two components
    to be put together? what is the corresponding amount of initial energy? To solve
    these questions, we model interfaces with resource requirements as games with
    quantitative objectives. The games are played on state spaces where each state
    is labeled by a number (representing, e.g., power consumption), and a play produces
    an infinite path of labels. The objective may be, for example, to minimize the
    largest label that occurs during a play. We illustrate our approach by modeling
    compatibility questions for the components of robot control software, and of wireless
    sensor networks.'
acknowledgement: This research was supported in part by the DARPA grant F33615-00-C-1693,
  the MARCO grant 98-DT-660, the ONR grant N00014-02-1-0671, and the NSF grants CCR-0085949,
  CCR-0132780, CCR-0234690, and CCR-9988172.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Arindam
  full_name: Chakrabarti, Arindam
  last_name: Chakrabarti
- first_name: Luca
  full_name: De Alfaro, Luca
  last_name: De Alfaro
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Mariëlle
  full_name: Stoelinga, Mariëlle
  last_name: Stoelinga
citation:
  ama: 'Chakrabarti A, De Alfaro L, Henzinger TA, Stoelinga M. Resource interfaces.
    In: <i>Third International Conference on Embedded Software</i>. Vol 2855. ACM;
    2003:117-133. doi:<a href="https://doi.org/10.1007/978-3-540-45212-6_9">10.1007/978-3-540-45212-6_9</a>'
  apa: 'Chakrabarti, A., De Alfaro, L., Henzinger, T. A., &#38; Stoelinga, M. (2003).
    Resource interfaces. In <i>Third International Conference on Embedded Software</i>
    (Vol. 2855, pp. 117–133). Philadelphia, PA, USA: ACM. <a href="https://doi.org/10.1007/978-3-540-45212-6_9">https://doi.org/10.1007/978-3-540-45212-6_9</a>'
  chicago: Chakrabarti, Arindam, Luca De Alfaro, Thomas A Henzinger, and Mariëlle
    Stoelinga. “Resource Interfaces.” In <i>Third International Conference on Embedded
    Software</i>, 2855:117–33. ACM, 2003. <a href="https://doi.org/10.1007/978-3-540-45212-6_9">https://doi.org/10.1007/978-3-540-45212-6_9</a>.
  ieee: A. Chakrabarti, L. De Alfaro, T. A. Henzinger, and M. Stoelinga, “Resource
    interfaces,” in <i>Third International Conference on Embedded Software</i>, Philadelphia,
    PA, USA, 2003, vol. 2855, pp. 117–133.
  ista: 'Chakrabarti A, De Alfaro L, Henzinger TA, Stoelinga M. 2003. Resource interfaces.
    Third International Conference on Embedded Software. EMSOFT: Embedded Software
    , LNCS, vol. 2855, 117–133.'
  mla: Chakrabarti, Arindam, et al. “Resource Interfaces.” <i>Third International
    Conference on Embedded Software</i>, vol. 2855, ACM, 2003, pp. 117–33, doi:<a
    href="https://doi.org/10.1007/978-3-540-45212-6_9">10.1007/978-3-540-45212-6_9</a>.
  short: A. Chakrabarti, L. De Alfaro, T.A. Henzinger, M. Stoelinga, in:, Third International
    Conference on Embedded Software, ACM, 2003, pp. 117–133.
conference:
  end_date: 2003-10-15
  location: Philadelphia, PA, USA
  name: 'EMSOFT: Embedded Software '
  start_date: 2003-10-13
date_created: 2018-12-11T12:09:29Z
date_published: 2003-09-29T00:00:00Z
date_updated: 2024-01-08T10:48:11Z
day: '29'
doi: 10.1007/978-3-540-45212-6_9
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-540-45212-6_9
intvolume: '      2855'
language:
- iso: eng
month: '09'
oa_version: None
page: 117 - 133
publication: Third International Conference on Embedded Software
publication_identifier:
  isbn:
  - '9783540202233'
publication_status: published
publisher: ACM
publist_id: '148'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Resource interfaces
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2855
year: '2003'
...
---
_id: '4628'
abstract:
- lang: eng
  text: 'Discounting the future means that the value, today, of a unit payoffis 1
    if the payoffo ccurs today, a if it occurs tomorrow, a 2 if it occurs the day
    after tomorrow, and so on, for some real-valued discount factor 0 &lt; a &lt;
    1. Discounting (or inflation) is a key paradigm in economics and has been studied
    in Markov decision processes as well as game theory. We submit that discounting
    also has a natural place in systems engineering: for nonterminating systems, a
    potential bug in the far-away future is less troubling than a potential bug today.
    We therefore develop a systems theory with discounting. Our theory includes several
    basic elements: discounted versions of system properties that correspond to the
    ω-regular properties, fixpoint-based algorithms for checking discounted properties,
    and a quantitative notion of bisimilarity for capturing the difference between
    two states with respect to discounted properties. We present the theory in a general
    form that applies to probabilistic systems as well as multicomponent systems (games),
    but it readily specializes to classical transition systems. We show that discounting,
    besides its natural practical appeal, has also several mathematical benefits.
    First, the resulting theory is robust, in that small perturbations of a system
    can cause only small changes in the properties of the system. Second, the theory
    is computational, in that the values of discounted properties, as well as the
    discounted bisimilarity distance between states, can be computed to any desired
    degree of precision.'
acknowledgement: This research was supported in part by the NSF CAREER award CCR-0132780,
  the DARPA grant F33615-C-98-3614, the NSF grants CCR-9988172, CCR-0234690 and CCR-0225610,
  and the ONR grant N00014-02-1-0671.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Luca
  full_name: De Alfaro, Luca
  last_name: De Alfaro
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Ritankar
  full_name: Majumdar, Ritankar
  last_name: Majumdar
citation:
  ama: 'De Alfaro L, Henzinger TA, Majumdar R. Discounting the future in systems theory.
    In: <i>Proceedings of the 30th International Colloquium on Automata, Languages
    and Programming</i>. Vol 2719. Springer; 2003:1022-1037. doi:<a href="https://doi.org/10.1007/3-540-45061-0_79">10.1007/3-540-45061-0_79</a>'
  apa: 'De Alfaro, L., Henzinger, T. A., &#38; Majumdar, R. (2003). Discounting the
    future in systems theory. In <i>Proceedings of the 30th International Colloquium
    on Automata, Languages and Programming</i> (Vol. 2719, pp. 1022–1037). Eindhoven,
    The Netherlands: Springer. <a href="https://doi.org/10.1007/3-540-45061-0_79">https://doi.org/10.1007/3-540-45061-0_79</a>'
  chicago: De Alfaro, Luca, Thomas A Henzinger, and Ritankar Majumdar. “Discounting
    the Future in Systems Theory.” In <i>Proceedings of the 30th International Colloquium
    on Automata, Languages and Programming</i>, 2719:1022–37. Springer, 2003. <a href="https://doi.org/10.1007/3-540-45061-0_79">https://doi.org/10.1007/3-540-45061-0_79</a>.
  ieee: L. De Alfaro, T. A. Henzinger, and R. Majumdar, “Discounting the future in
    systems theory,” in <i>Proceedings of the 30th International Colloquium on Automata,
    Languages and Programming</i>, Eindhoven, The Netherlands, 2003, vol. 2719, pp.
    1022–1037.
  ista: 'De Alfaro L, Henzinger TA, Majumdar R. 2003. Discounting the future in systems
    theory. Proceedings of the 30th International Colloquium on Automata, Languages
    and Programming. ICALP: Automata, Languages and Programming, LNCS, vol. 2719,
    1022–1037.'
  mla: De Alfaro, Luca, et al. “Discounting the Future in Systems Theory.” <i>Proceedings
    of the 30th International Colloquium on Automata, Languages and Programming</i>,
    vol. 2719, Springer, 2003, pp. 1022–37, doi:<a href="https://doi.org/10.1007/3-540-45061-0_79">10.1007/3-540-45061-0_79</a>.
  short: L. De Alfaro, T.A. Henzinger, R. Majumdar, in:, Proceedings of the 30th International
    Colloquium on Automata, Languages and Programming, Springer, 2003, pp. 1022–1037.
conference:
  end_date: 2003-07-04
  location: Eindhoven, The Netherlands
  name: 'ICALP: Automata, Languages and Programming'
  start_date: 2003-06-30
date_created: 2018-12-11T12:09:50Z
date_published: 2003-06-25T00:00:00Z
date_updated: 2023-07-26T13:07:31Z
day: '25'
doi: 10.1007/3-540-45061-0_79
extern: '1'
fulldoi: https://doi.org/10.1007/3-540-45061-0_79
intvolume: '      2719'
language:
- iso: eng
month: '06'
oa_version: None
page: 1022 - 1037
publication: Proceedings of the 30th International Colloquium on Automata, Languages
  and Programming
publication_identifier:
  isbn:
  - '9783540404934'
publication_status: published
publisher: Springer
publist_id: '77'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Discounting the future in systems theory
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2719
year: '2003'
...
---
_id: '4630'
abstract:
- lang: eng
  text: We consider concurrent two-person games played in real time, in which the
    players decide both which action to play, and when to play it. Such timed games
    differ from untimed games in two essential ways. First, players can take each
    other by surprise, because actions are played with delays that cannot be anticipated
    by the opponent. Second, a player should not be able to win the game by preventing
    time from diverging. We present a model of timed games that preserves the element
    of surprise and accounts for time divergence in a way that treats both players
    symmetrically and applies to all ω-regular winning conditions. We prove that the
    ability to take each other by surprise adds extra power to the players. For the
    case that the games are specified in the style of timed automata, we provide symbolic
    algorithms for their solution with respect to all ω-regular winning conditions.
    We also show that for these timed games, memory strategies are more powerful than
    memoryless strategies already in the case of reachability objectives.
acknowledgement: Supported in part by the AFOSR MURI grant F49620-00-1-0327, the DARPA
  grant F33615-C-98-3614, the MARCO grant 98-DT-660, -the ONR grant N00014-02-1-0671,
  the NSF grants CCR-9988172, CCR-0225610, and CCR-0234690, the NSF CAREER award CCR-0132780,
  and the MIUR grant MEFISTO.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Luca
  full_name: De Alfaro, Luca
  last_name: De Alfaro
- first_name: Marco
  full_name: Faella, Marco
  last_name: Faella
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Ritankar
  full_name: Majumdar, Ritankar
  last_name: Majumdar
- first_name: Mariëlle
  full_name: Stoelinga, Mariëlle
  last_name: Stoelinga
citation:
  ama: 'De Alfaro L, Faella M, Henzinger TA, Majumdar R, Stoelinga M. The element
    of surprise in timed games. In: <i>Proceedings of the 14th International Conference
    on Concurrency Theory</i>. Vol 2761. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
    2003:144-158. doi:<a href="https://doi.org/10.1007/978-3-540-45187-7_9">10.1007/978-3-540-45187-7_9</a>'
  apa: 'De Alfaro, L., Faella, M., Henzinger, T. A., Majumdar, R., &#38; Stoelinga,
    M. (2003). The element of surprise in timed games. In <i>Proceedings of the 14th
    International Conference on Concurrency Theory</i> (Vol. 2761, pp. 144–158). Marseille,
    France: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.1007/978-3-540-45187-7_9">https://doi.org/10.1007/978-3-540-45187-7_9</a>'
  chicago: De Alfaro, Luca, Marco Faella, Thomas A Henzinger, Ritankar Majumdar, and
    Mariëlle Stoelinga. “The Element of Surprise in Timed Games.” In <i>Proceedings
    of the 14th International Conference on Concurrency Theory</i>, 2761:144–58. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2003. <a href="https://doi.org/10.1007/978-3-540-45187-7_9">https://doi.org/10.1007/978-3-540-45187-7_9</a>.
  ieee: L. De Alfaro, M. Faella, T. A. Henzinger, R. Majumdar, and M. Stoelinga, “The
    element of surprise in timed games,” in <i>Proceedings of the 14th International
    Conference on Concurrency Theory</i>, Marseille, France, 2003, vol. 2761, pp.
    144–158.
  ista: 'De Alfaro L, Faella M, Henzinger TA, Majumdar R, Stoelinga M. 2003. The element
    of surprise in timed games. Proceedings of the 14th International Conference on
    Concurrency Theory. CONCUR: Concurrency Theory, LNCS, vol. 2761, 144–158.'
  mla: De Alfaro, Luca, et al. “The Element of Surprise in Timed Games.” <i>Proceedings
    of the 14th International Conference on Concurrency Theory</i>, vol. 2761, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2003, pp. 144–58, doi:<a href="https://doi.org/10.1007/978-3-540-45187-7_9">10.1007/978-3-540-45187-7_9</a>.
  short: L. De Alfaro, M. Faella, T.A. Henzinger, R. Majumdar, M. Stoelinga, in:,
    Proceedings of the 14th International Conference on Concurrency Theory, Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik, 2003, pp. 144–158.
conference:
  end_date: 2003-09-05
  location: Marseille, France
  name: 'CONCUR: Concurrency Theory'
  start_date: 2003-09-03
date_created: 2018-12-11T12:09:51Z
date_published: 2003-08-21T00:00:00Z
date_updated: 2024-01-08T10:05:30Z
day: '21'
doi: 10.1007/978-3-540-45187-7_9
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-540-45187-7_9
intvolume: '      2761'
language:
- iso: eng
month: '08'
oa_version: None
page: 144 - 158
publication: Proceedings of the 14th International Conference on Concurrency Theory
publication_identifier:
  isbn:
  - '9783540407539'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '78'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The element of surprise in timed games
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2761
year: '2003'
...
---
OA_place: repository
OA_type: green
_id: '576'
abstract:
- lang: eng
  text: 'We study the free expansion of a pancake-shaped Bose-condensed gas, which
    is initially trapped under harmonic confinement and containing a vortex at its
    centre. In the case of a radial expansion holding the axial confinement fixed
    we consider various models for the interactions, depending on the thickness of
    the condensate relative to the value of the scattering length. We are thus able
    to evaluate different scattering regimes ranging from quasi-three-dimensional
    (Q3D) to strictly two-dimensional (2D). We find that as the system goes from Q3D
    to 2D the expansion rate of the condensate increases whereas that of the vortex
    core decreases. In the Q3D scattering regime we also examine a fully free expansion
    in 3D and find oscillatory behaviour for the vortex core radius: an initial fast
    expansion of the vortex core is followed by a slowing down. Such a nonuniform
    expansion rate of the vortex core implies that the timing of its observation should
    be chosen appropriately.'
article_number: '2455'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
- first_name: Patrizia
  full_name: Vignolo, Patrizia
  last_name: Vignolo
- first_name: Anna
  full_name: Minguzzi, Anna
  last_name: Minguzzi
- first_name: Bilal
  full_name: Tanatar, Bilal
  last_name: Tanatar
- first_name: Mario
  full_name: Tosi, Mario
  last_name: Tosi
citation:
  ama: 'Hosten O, Vignolo P, Minguzzi A, Tanatar B, Tosi M. Free expansion of two-dimensional
    condensates with a vortex. <i>Journal of Physics B: Atomic, Molecular and Optical
    Physics</i>. 2003;36(12). doi:<a href="https://doi.org/10.1088/0953-4075/36/12/306">10.1088/0953-4075/36/12/306</a>'
  apa: 'Hosten, O., Vignolo, P., Minguzzi, A., Tanatar, B., &#38; Tosi, M. (2003).
    Free expansion of two-dimensional condensates with a vortex. <i>Journal of Physics
    B: Atomic, Molecular and Optical Physics</i>. IOP Publishing . <a href="https://doi.org/10.1088/0953-4075/36/12/306">https://doi.org/10.1088/0953-4075/36/12/306</a>'
  chicago: 'Hosten, Onur, Patrizia Vignolo, Anna Minguzzi, Bilal Tanatar, and Mario
    Tosi. “Free Expansion of Two-Dimensional Condensates with a Vortex.” <i>Journal
    of Physics B: Atomic, Molecular and Optical Physics</i>. IOP Publishing , 2003.
    <a href="https://doi.org/10.1088/0953-4075/36/12/306">https://doi.org/10.1088/0953-4075/36/12/306</a>.'
  ieee: 'O. Hosten, P. Vignolo, A. Minguzzi, B. Tanatar, and M. Tosi, “Free expansion
    of two-dimensional condensates with a vortex,” <i>Journal of Physics B: Atomic,
    Molecular and Optical Physics</i>, vol. 36, no. 12. IOP Publishing , 2003.'
  ista: 'Hosten O, Vignolo P, Minguzzi A, Tanatar B, Tosi M. 2003. Free expansion
    of two-dimensional condensates with a vortex. Journal of Physics B: Atomic, Molecular
    and Optical Physics. 36(12), 2455.'
  mla: 'Hosten, Onur, et al. “Free Expansion of Two-Dimensional Condensates with a
    Vortex.” <i>Journal of Physics B: Atomic, Molecular and Optical Physics</i>, vol.
    36, no. 12, 2455, IOP Publishing , 2003, doi:<a href="https://doi.org/10.1088/0953-4075/36/12/306">10.1088/0953-4075/36/12/306</a>.'
  short: 'O. Hosten, P. Vignolo, A. Minguzzi, B. Tanatar, M. Tosi, Journal of Physics
    B: Atomic, Molecular and Optical Physics 36 (2003).'
date_created: 2018-12-11T11:47:16Z
date_published: 2003-06-28T00:00:00Z
date_updated: 2026-05-28T14:23:40Z
day: '28'
doi: 10.1088/0953-4075/36/12/306
extern: '1'
external_id:
  arxiv:
  - '0303244'
fulldoi: https://doi.org/10.1088/0953-4075/36/12/306
intvolume: '        36'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.cond-mat/0303244'
month: '06'
oa: 1
oa_version: Preprint
publication: 'Journal of Physics B: Atomic, Molecular and Optical Physics'
publication_identifier:
  eissn:
  - 1361-6455
  issn:
  - 0953-4075
publication_status: published
publisher: 'IOP Publishing '
publist_id: '7239'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Free expansion of two-dimensional condensates with a vortex
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 36
year: '2003'
...
---
_id: '6156'
abstract:
- lang: eng
  text: 'Social and solitary feeding in natural Caenorhabditis elegans isolates are
    associated with two alleles of the orphan G-protein-coupled receptor (GPCR) NPR-1:
    social feeders contain NPR-1 215F, whereas solitary feeders contain NPR-1 215V.
    Here we identify FMRFamide-related neuropeptides (FaRPs) encoded by the flp-18
    and flp-21 genes as NPR-1 ligands and show that these peptides can differentially
    activate the NPR-1 215F and NPR-1 215V receptors. Multicopy overexpression of
    flp-21 transformed wild social animals into solitary feeders. Conversely, a flp-21
    deletion partially phenocopied the npr-1(null) phenotype, which is consistent
    with NPR-1 activation by FLP-21 in vivo but also implicates other ligands for
    NPR-1. Phylogenetic studies indicate that the dominant npr-1 215V allele likely
    arose from an ancestral npr-1 215F gene in C. elegans. Our data suggest a model
    in which solitary feeding evolved in an ancestral social strain of C. elegans
    by a gain-of-function mutation that modified the response of NPR-1 to FLP-18 and
    FLP-21 ligands.'
author:
- first_name: Candida
  full_name: Rogers, Candida
  last_name: Rogers
- first_name: Vincenzina
  full_name: Reale, Vincenzina
  last_name: Reale
- first_name: Kyuhyung
  full_name: Kim, Kyuhyung
  last_name: Kim
- first_name: Heather
  full_name: Chatwin, Heather
  last_name: Chatwin
- first_name: Chris
  full_name: Li, Chris
  last_name: Li
- first_name: Peter
  full_name: Evans, Peter
  last_name: Evans
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Rogers C, Reale V, Kim K, et al. Inhibition of Caenorhabditis elegans social
    feeding by FMRFamide-related peptide activation of NPR-1. <i>Nature Neuroscience</i>.
    2003;6(11):1178-1185. doi:<a href="https://doi.org/10.1038/nn1140">10.1038/nn1140</a>
  apa: Rogers, C., Reale, V., Kim, K., Chatwin, H., Li, C., Evans, P., &#38; de Bono,
    M. (2003). Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related
    peptide activation of NPR-1. <i>Nature Neuroscience</i>. Springer Nature. <a href="https://doi.org/10.1038/nn1140">https://doi.org/10.1038/nn1140</a>
  chicago: Rogers, Candida, Vincenzina Reale, Kyuhyung Kim, Heather Chatwin, Chris
    Li, Peter Evans, and Mario de Bono. “Inhibition of Caenorhabditis Elegans Social
    Feeding by FMRFamide-Related Peptide Activation of NPR-1.” <i>Nature Neuroscience</i>.
    Springer Nature, 2003. <a href="https://doi.org/10.1038/nn1140">https://doi.org/10.1038/nn1140</a>.
  ieee: C. Rogers <i>et al.</i>, “Inhibition of Caenorhabditis elegans social feeding
    by FMRFamide-related peptide activation of NPR-1,” <i>Nature Neuroscience</i>,
    vol. 6, no. 11. Springer Nature, pp. 1178–1185, 2003.
  ista: Rogers C, Reale V, Kim K, Chatwin H, Li C, Evans P, de Bono M. 2003. Inhibition
    of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation
    of NPR-1. Nature Neuroscience. 6(11), 1178–1185.
  mla: Rogers, Candida, et al. “Inhibition of Caenorhabditis Elegans Social Feeding
    by FMRFamide-Related Peptide Activation of NPR-1.” <i>Nature Neuroscience</i>,
    vol. 6, no. 11, Springer Nature, 2003, pp. 1178–85, doi:<a href="https://doi.org/10.1038/nn1140">10.1038/nn1140</a>.
  short: C. Rogers, V. Reale, K. Kim, H. Chatwin, C. Li, P. Evans, M. de Bono, Nature
    Neuroscience 6 (2003) 1178–1185.
date_created: 2019-03-21T09:47:53Z
date_published: 2003-10-12T00:00:00Z
date_updated: 2021-01-12T08:06:25Z
day: '12'
doi: 10.1038/nn1140
extern: '1'
external_id:
  pmid:
  - '14555955'
fulldoi: https://doi.org/10.1038/nn1140
intvolume: '         6'
issue: '11'
language:
- iso: eng
month: '10'
oa_version: None
page: 1178-1185
pmid: 1
publication: Nature Neuroscience
publication_identifier:
  issn:
  - 1097-6256
  - 1546-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide
  activation of NPR-1
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2003'
...
---
_id: '6157'
abstract:
- lang: eng
  text: In many animal species individuals aggregate to live in groups. A range of
    experimental approaches in different animals, including studies of social feeding
    in nematodes, maternal behavior in rats and sheep, and pair-bonding in voles,
    are providing insights into the neural bases for these behaviors. These studies
    are delineating multiple neural circuits and gene networks in the brain that interact
    in ways that are as yet poorly understood to coordinate social behavior.
author:
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: de Bono M. Molecular approaches to aggregation behavior and social attachment.
    <i>Journal of Neurobiology</i>. 2003;54(1):78-92. doi:<a href="https://doi.org/10.1002/neu.10162">10.1002/neu.10162</a>
  apa: de Bono, M. (2003). Molecular approaches to aggregation behavior and social
    attachment. <i>Journal of Neurobiology</i>. Wiley. <a href="https://doi.org/10.1002/neu.10162">https://doi.org/10.1002/neu.10162</a>
  chicago: Bono, Mario de. “Molecular Approaches to Aggregation Behavior and Social
    Attachment.” <i>Journal of Neurobiology</i>. Wiley, 2003. <a href="https://doi.org/10.1002/neu.10162">https://doi.org/10.1002/neu.10162</a>.
  ieee: M. de Bono, “Molecular approaches to aggregation behavior and social attachment,”
    <i>Journal of Neurobiology</i>, vol. 54, no. 1. Wiley, pp. 78–92, 2003.
  ista: de Bono M. 2003. Molecular approaches to aggregation behavior and social attachment.
    Journal of Neurobiology. 54(1), 78–92.
  mla: de Bono, Mario. “Molecular Approaches to Aggregation Behavior and Social Attachment.”
    <i>Journal of Neurobiology</i>, vol. 54, no. 1, Wiley, 2003, pp. 78–92, doi:<a
    href="https://doi.org/10.1002/neu.10162">10.1002/neu.10162</a>.
  short: M. de Bono, Journal of Neurobiology 54 (2003) 78–92.
date_created: 2019-03-21T09:52:31Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T08:06:26Z
day: '01'
doi: 10.1002/neu.10162
extern: '1'
external_id:
  pmid:
  - '12486699'
fulldoi: https://doi.org/10.1002/neu.10162
intvolume: '        54'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 78-92
pmid: 1
publication: Journal of Neurobiology
publication_identifier:
  issn:
  - 0022-3034
  - 1097-4695
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Molecular approaches to aggregation behavior and social attachment
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2003'
...
---
OA_type: closed access
_id: '205'
article_processing_charge: No
article_type: original
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
citation:
  ama: Browning TD. Counting rational points on cubic and quartic surfaces. <i>Acta
    Arithmetica</i>. 2003;108:275-295. doi:<a href="https://doi.org/10.4064/aa108-3-7">10.4064/aa108-3-7</a>
  apa: Browning, T. D. (2003). Counting rational points on cubic and quartic surfaces.
    <i>Acta Arithmetica</i>. Instytut Matematyczny. <a href="https://doi.org/10.4064/aa108-3-7">https://doi.org/10.4064/aa108-3-7</a>
  chicago: Browning, Timothy D. “Counting Rational Points on Cubic and Quartic Surfaces.”
    <i>Acta Arithmetica</i>. Instytut Matematyczny, 2003. <a href="https://doi.org/10.4064/aa108-3-7">https://doi.org/10.4064/aa108-3-7</a>.
  ieee: T. D. Browning, “Counting rational points on cubic and quartic surfaces,”
    <i>Acta Arithmetica</i>, vol. 108. Instytut Matematyczny, pp. 275–295, 2003.
  ista: Browning TD. 2003. Counting rational points on cubic and quartic surfaces.
    Acta Arithmetica. 108, 275–295.
  mla: Browning, Timothy D. “Counting Rational Points on Cubic and Quartic Surfaces.”
    <i>Acta Arithmetica</i>, vol. 108, Instytut Matematyczny, 2003, pp. 275–95, doi:<a
    href="https://doi.org/10.4064/aa108-3-7">10.4064/aa108-3-7</a>.
  short: T.D. Browning, Acta Arithmetica 108 (2003) 275–295.
date_created: 2018-12-11T11:45:12Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2026-05-29T07:22:53Z
day: '01'
doi: 10.4064/aa108-3-7
extern: '1'
fulldoi: https://doi.org/10.4064/aa108-3-7
intvolume: '       108'
language:
- iso: eng
month: '01'
oa_version: None
page: 275 - 295
publication: Acta Arithmetica
publication_identifier:
  eissn:
  - 1730-6264
  issn:
  - 0065-1036
publication_status: published
publisher: Instytut Matematyczny
publist_id: '7707'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Counting rational points on cubic and quartic surfaces
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 108
year: '2003'
...
---
OA_type: closed access
_id: '206'
abstract:
- lang: eng
  text: Let T ⊂ ℙ 4 be a non-singular threefold of degree at least four. Then we show
    that the number of points in T(ℚ), with height at most B, is o(B 3) or B → ∞.
article_processing_charge: No
article_type: original
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
citation:
  ama: Browning TD. A note on the distribution of rational points on threefolds. <i>Quarterly
    Journal of Mathematics</i>. 2003;54(1):33-39. doi:<a href="https://doi.org/10.1093/qjmath/54.1.33">10.1093/qjmath/54.1.33</a>
  apa: Browning, T. D. (2003). A note on the distribution of rational points on threefolds.
    <i>Quarterly Journal of Mathematics</i>. Unknown. <a href="https://doi.org/10.1093/qjmath/54.1.33">https://doi.org/10.1093/qjmath/54.1.33</a>
  chicago: Browning, Timothy D. “A Note on the Distribution of Rational Points on
    Threefolds.” <i>Quarterly Journal of Mathematics</i>. Unknown, 2003. <a href="https://doi.org/10.1093/qjmath/54.1.33">https://doi.org/10.1093/qjmath/54.1.33</a>.
  ieee: T. D. Browning, “A note on the distribution of rational points on threefolds,”
    <i>Quarterly Journal of Mathematics</i>, vol. 54, no. 1. Unknown, pp. 33–39, 2003.
  ista: Browning TD. 2003. A note on the distribution of rational points on threefolds.
    Quarterly Journal of Mathematics. 54(1), 33–39.
  mla: Browning, Timothy D. “A Note on the Distribution of Rational Points on Threefolds.”
    <i>Quarterly Journal of Mathematics</i>, vol. 54, no. 1, Unknown, 2003, pp. 33–39,
    doi:<a href="https://doi.org/10.1093/qjmath/54.1.33">10.1093/qjmath/54.1.33</a>.
  short: T.D. Browning, Quarterly Journal of Mathematics 54 (2003) 33–39.
date_created: 2018-12-11T11:45:12Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2026-05-29T07:14:27Z
day: '01'
doi: 10.1093/qjmath/54.1.33
extern: '1'
fulldoi: https://doi.org/10.1093/qjmath/54.1.33
intvolume: '        54'
issue: '1'
language:
- iso: eng
month: '03'
oa_version: None
page: 33 - 39
publication: Quarterly Journal of Mathematics
publication_identifier:
  eissn:
  - 1464-3847
  issn:
  - 0033-5606
publication_status: published
publisher: Unknown
publist_id: '7706'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A note on the distribution of rational points on threefolds
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 54
year: '2003'
...
---
_id: '207'
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
citation:
  ama: Browning TD. Sums of four biquadrates. <i>Mathematical Proceedings of the Cambridge
    Philosophical Society</i>. 2003;134(3):385-395. doi:<a href="https://doi.org/10.1017/S0305004102006382">10.1017/S0305004102006382</a>
  apa: Browning, T. D. (2003). Sums of four biquadrates. <i>Mathematical Proceedings
    of the Cambridge Philosophical Society</i>. Cambridge University Press. <a href="https://doi.org/10.1017/S0305004102006382">https://doi.org/10.1017/S0305004102006382</a>
  chicago: Browning, Timothy D. “Sums of Four Biquadrates.” <i>Mathematical Proceedings
    of the Cambridge Philosophical Society</i>. Cambridge University Press, 2003.
    <a href="https://doi.org/10.1017/S0305004102006382">https://doi.org/10.1017/S0305004102006382</a>.
  ieee: T. D. Browning, “Sums of four biquadrates,” <i>Mathematical Proceedings of
    the Cambridge Philosophical Society</i>, vol. 134, no. 3. Cambridge University
    Press, pp. 385–395, 2003.
  ista: Browning TD. 2003. Sums of four biquadrates. Mathematical Proceedings of the
    Cambridge Philosophical Society. 134(3), 385–395.
  mla: Browning, Timothy D. “Sums of Four Biquadrates.” <i>Mathematical Proceedings
    of the Cambridge Philosophical Society</i>, vol. 134, no. 3, Cambridge University
    Press, 2003, pp. 385–95, doi:<a href="https://doi.org/10.1017/S0305004102006382">10.1017/S0305004102006382</a>.
  short: T.D. Browning, Mathematical Proceedings of the Cambridge Philosophical Society
    134 (2003) 385–395.
date_created: 2018-12-11T11:45:12Z
date_published: 2003-05-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1017/S0305004102006382
extern: '1'
fulldoi: https://doi.org/10.1017/S0305004102006382
intvolume: '       134'
issue: '3'
language:
- iso: eng
month: '05'
oa_version: None
page: 385 - 395
publication: Mathematical Proceedings of the Cambridge Philosophical Society
publication_status: published
publisher: Cambridge University Press
publist_id: '7704'
quality_controlled: '1'
status: public
title: Sums of four biquadrates
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 134
year: '2003'
...
---
OA_type: closed access
_id: '208'
abstract:
- lang: eng
  text: "For any ε > 0 and any diagonal quadratic form Q ∈ Z[x1, x2, x3, x4] with
    a square‐free discriminant of modulus ΔQ ≠ 0, we establish the uniform estimate
    ≪ε B3/2+ε + B2+ε/Δ1/6Q for the number of rational points of height at most B lying
    in the projective surface Q = 0.\r\n\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
citation:
  ama: Browning TD. Counting rational points on diagonal quadratic surfaces. <i>Quarterly
    Journal of Mathematics</i>. 2003;54(1):11-31. doi:<a href="https://doi.org/doi/10.1093/qjmath/54.1.11">doi/10.1093/qjmath/54.1.11</a>
  apa: Browning, T. D. (2003). Counting rational points on diagonal quadratic surfaces.
    <i>Quarterly Journal of Mathematics</i>. Oxford Academic. <a href="https://doi.org/doi/10.1093/qjmath/54.1.11">https://doi.org/doi/10.1093/qjmath/54.1.11</a>
  chicago: Browning, Timothy D. “Counting Rational Points on Diagonal Quadratic Surfaces.”
    <i>Quarterly Journal of Mathematics</i>. Oxford Academic, 2003. <a href="https://doi.org/doi/10.1093/qjmath/54.1.11">https://doi.org/doi/10.1093/qjmath/54.1.11</a>.
  ieee: T. D. Browning, “Counting rational points on diagonal quadratic surfaces,”
    <i>Quarterly Journal of Mathematics</i>, vol. 54, no. 1. Oxford Academic, pp.
    11–31, 2003.
  ista: Browning TD. 2003. Counting rational points on diagonal quadratic surfaces.
    Quarterly Journal of Mathematics. 54(1), 11–31.
  mla: Browning, Timothy D. “Counting Rational Points on Diagonal Quadratic Surfaces.”
    <i>Quarterly Journal of Mathematics</i>, vol. 54, no. 1, Oxford Academic, 2003,
    pp. 11–31, doi:<a href="https://doi.org/doi/10.1093/qjmath/54.1.11">doi/10.1093/qjmath/54.1.11</a>.
  short: T.D. Browning, Quarterly Journal of Mathematics 54 (2003) 11–31.
date_created: 2018-12-11T11:45:13Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2026-05-29T07:10:52Z
day: '01'
doi: doi/10.1093/qjmath/54.1.11
extern: '1'
fulldoi: https://doi.org/doi/10.1093/qjmath/54.1.11
intvolume: '        54'
issue: '1'
language:
- iso: eng
month: '03'
oa_version: None
page: 11 - 31
publication: Quarterly Journal of Mathematics
publication_identifier:
  eissn:
  - 1464-3847
  issn:
  - 0033-5606
publication_status: published
publisher: Oxford Academic
publist_id: '7705'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Counting rational points on diagonal quadratic surfaces
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 54
year: '2003'
...
---
OA_type: closed access
_id: '847'
abstract:
- lang: eng
  text: The accumulation of genome-wide information on single nucleotide polymorphisms
    in humans provides an unprecedented opportunity to detect the evolutionary forces
    responsible for heterogeneity of the level of genetic variability across loci.
    Previous studies have shown that history of recombination events has produced
    long haplotype blocks in the human genome, which contribute to this heterogeneity.
    Other factors, however, such as natural selection or the heterogeneity of mutation
    rates across loci, may also lead to heterogeneity of genetic variability. We compared
    synonymous and non-synonymous variability within human genes with their divergence
    from murine orthologs. We separately analyzed the non-synonymous variants predicted
    to damage protein structure or function and the variants predicted to be functionally
    benign. The predictions were based on comparative sequence analysis and, in some
    cases, on the analysis of protein structure. A strong correlation between non-synonymous,
    benign variability and non-synonymous human-mouse divergence suggests that selection
    played an important role in shaping the pattern of variability in coding regions
    of human genes. However, the lack of correlation between deleterious variability
    and evolutionary divergence shows that a substantial proportion of the observed
    non-synonymous single-nucleotide polymorphisms reduces fitness and never reaches
    fixation. Evolutionary and medical implications of the impact of selection on
    human polymorphisms are discussed.
acknowledgement: We are grateful to Alexey Kondrashov and Alison Wellman for the careful
  reading of the manuscript and providing us with their valuable comments.
article_processing_charge: No
article_type: original
author:
- first_name: Shamil
  full_name: Sunyaev, Shamil
  last_name: Sunyaev
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Peer
  full_name: Bork, Peer
  last_name: Bork
- first_name: Vasily
  full_name: Ramensky, Vasily
  last_name: Ramensky
citation:
  ama: Sunyaev S, Kondrashov F, Bork P, Ramensky V. Impact of selection, mutation
    rate and genetic drift on human genetic variation. <i>Human Molecular Genetics</i>.
    2003;12(24):3325-3330. doi:<a href="https://doi.org/10.1093/hmg/ddg359">10.1093/hmg/ddg359</a>
  apa: Sunyaev, S., Kondrashov, F., Bork, P., &#38; Ramensky, V. (2003). Impact of
    selection, mutation rate and genetic drift on human genetic variation. <i>Human
    Molecular Genetics</i>. Oxford Academic. <a href="https://doi.org/10.1093/hmg/ddg359">https://doi.org/10.1093/hmg/ddg359</a>
  chicago: Sunyaev, Shamil, Fyodor Kondrashov, Peer Bork, and Vasily Ramensky. “Impact
    of Selection, Mutation Rate and Genetic Drift on Human Genetic Variation.” <i>Human
    Molecular Genetics</i>. Oxford Academic, 2003. <a href="https://doi.org/10.1093/hmg/ddg359">https://doi.org/10.1093/hmg/ddg359</a>.
  ieee: S. Sunyaev, F. Kondrashov, P. Bork, and V. Ramensky, “Impact of selection,
    mutation rate and genetic drift on human genetic variation,” <i>Human Molecular
    Genetics</i>, vol. 12, no. 24. Oxford Academic, pp. 3325–3330, 2003.
  ista: Sunyaev S, Kondrashov F, Bork P, Ramensky V. 2003. Impact of selection, mutation
    rate and genetic drift on human genetic variation. Human Molecular Genetics. 12(24),
    3325–3330.
  mla: Sunyaev, Shamil, et al. “Impact of Selection, Mutation Rate and Genetic Drift
    on Human Genetic Variation.” <i>Human Molecular Genetics</i>, vol. 12, no. 24,
    Oxford Academic, 2003, pp. 3325–30, doi:<a href="https://doi.org/10.1093/hmg/ddg359">10.1093/hmg/ddg359</a>.
  short: S. Sunyaev, F. Kondrashov, P. Bork, V. Ramensky, Human Molecular Genetics
    12 (2003) 3325–3330.
date_created: 2018-12-11T11:48:49Z
date_published: 2003-12-15T00:00:00Z
date_updated: 2026-05-28T14:13:45Z
day: '15'
doi: 10.1093/hmg/ddg359
extern: '1'
external_id:
  pmid:
  - '14570704 '
fulldoi: https://doi.org/10.1093/hmg/ddg359
intvolume: '        12'
issue: '24'
language:
- iso: eng
month: '12'
oa_version: None
page: 3325 - 3330
pmid: 1
publication: Human Molecular Genetics
publication_identifier:
  eissn:
  - 1460-2083
  issn:
  - 0964-6906
publication_status: published
publisher: Oxford Academic
publist_id: '6803'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Impact of selection, mutation rate and genetic drift on human genetic variation
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 12
year: '2003'
...
---
_id: '8519'
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
citation:
  ama: Kaloshin V. The existential Hilbert 16-th problem and an estimate for cyclicity
    of elementary polycycles. <i>Inventiones mathematicae</i>. 2003;151(3):451-512.
    doi:<a href="https://doi.org/10.1007/s00222-002-0244-9">10.1007/s00222-002-0244-9</a>
  apa: Kaloshin, V. (2003). The existential Hilbert 16-th problem and an estimate
    for cyclicity of elementary polycycles. <i>Inventiones Mathematicae</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00222-002-0244-9">https://doi.org/10.1007/s00222-002-0244-9</a>
  chicago: Kaloshin, Vadim. “The Existential Hilbert 16-Th Problem and an Estimate
    for Cyclicity of Elementary Polycycles.” <i>Inventiones Mathematicae</i>. Springer
    Nature, 2003. <a href="https://doi.org/10.1007/s00222-002-0244-9">https://doi.org/10.1007/s00222-002-0244-9</a>.
  ieee: V. Kaloshin, “The existential Hilbert 16-th problem and an estimate for cyclicity
    of elementary polycycles,” <i>Inventiones mathematicae</i>, vol. 151, no. 3. Springer
    Nature, pp. 451–512, 2003.
  ista: Kaloshin V. 2003. The existential Hilbert 16-th problem and an estimate for
    cyclicity of elementary polycycles. Inventiones mathematicae. 151(3), 451–512.
  mla: Kaloshin, Vadim. “The Existential Hilbert 16-Th Problem and an Estimate for
    Cyclicity of Elementary Polycycles.” <i>Inventiones Mathematicae</i>, vol. 151,
    no. 3, Springer Nature, 2003, pp. 451–512, doi:<a href="https://doi.org/10.1007/s00222-002-0244-9">10.1007/s00222-002-0244-9</a>.
  short: V. Kaloshin, Inventiones Mathematicae 151 (2003) 451–512.
date_created: 2020-09-18T10:49:26Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2021-01-12T08:19:50Z
day: '01'
doi: 10.1007/s00222-002-0244-9
extern: '1'
fulldoi: https://doi.org/10.1007/s00222-002-0244-9
intvolume: '       151'
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
month: '03'
oa_version: None
page: 451-512
publication: Inventiones mathematicae
publication_identifier:
  issn:
  - 0020-9910
  - 1432-1297
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: The existential Hilbert 16-th problem and an estimate for cyclicity of elementary
  polycycles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 151
year: '2003'
...
---
OA_type: closed access
_id: '876'
abstract:
- lang: eng
  text: Alternative splicing is thought to be a major source of functional diversity
    in animal proteins. We analyzed the evolutionary conservation of proteins encoded
    by alternatively spliced genes and predicted the ancestral state for 73 cases
    of alternative splicing (25 insertions and 48 deletions). The amino acid sequences
    of most of the inserts in proteins produced by alternative splicing are as conserved
    as the surrounding sequences. Thus, alternative splicing often creates novel isoforms
    by the insertion of new, functional protein sequences that probably originated
    from noncoding sequences of introns.
acknowledgement: We thank Peer Bork, Mikhail Gelfand, Alexey Kondrashov, David Lipman
  and Shamil Sunyaev for critical reading of the manuscript and useful suggestions
  and the Koonin group members for helpful discussions.
article_processing_charge: No
article_type: original
author:
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Eugene
  full_name: Koonin, Eugene
  last_name: Koonin
citation:
  ama: 'Kondrashov F, Koonin E. Evolution of alternative splicing: Deletions, insertions
    and origin of functional parts of proteins from intron sequences. <i>Trends in
    Genetics</i>. 2003;19(3):115-119. doi:<a href="https://doi.org/10.1016/S0168-9525(02)00029-X">10.1016/S0168-9525(02)00029-X</a>'
  apa: 'Kondrashov, F., &#38; Koonin, E. (2003). Evolution of alternative splicing:
    Deletions, insertions and origin of functional parts of proteins from intron sequences.
    <i>Trends in Genetics</i>. Elsevier. <a href="https://doi.org/10.1016/S0168-9525(02)00029-X">https://doi.org/10.1016/S0168-9525(02)00029-X</a>'
  chicago: 'Kondrashov, Fyodor, and Eugene Koonin. “Evolution of Alternative Splicing:
    Deletions, Insertions and Origin of Functional Parts of Proteins from Intron Sequences.”
    <i>Trends in Genetics</i>. Elsevier, 2003. <a href="https://doi.org/10.1016/S0168-9525(02)00029-X">https://doi.org/10.1016/S0168-9525(02)00029-X</a>.'
  ieee: 'F. Kondrashov and E. Koonin, “Evolution of alternative splicing: Deletions,
    insertions and origin of functional parts of proteins from intron sequences,”
    <i>Trends in Genetics</i>, vol. 19, no. 3. Elsevier, pp. 115–119, 2003.'
  ista: 'Kondrashov F, Koonin E. 2003. Evolution of alternative splicing: Deletions,
    insertions and origin of functional parts of proteins from intron sequences. Trends
    in Genetics. 19(3), 115–119.'
  mla: 'Kondrashov, Fyodor, and Eugene Koonin. “Evolution of Alternative Splicing:
    Deletions, Insertions and Origin of Functional Parts of Proteins from Intron Sequences.”
    <i>Trends in Genetics</i>, vol. 19, no. 3, Elsevier, 2003, pp. 115–19, doi:<a
    href="https://doi.org/10.1016/S0168-9525(02)00029-X">10.1016/S0168-9525(02)00029-X</a>.'
  short: F. Kondrashov, E. Koonin, Trends in Genetics 19 (2003) 115–119.
date_created: 2018-12-11T11:48:58Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2026-05-28T13:49:56Z
day: '01'
doi: 10.1016/S0168-9525(02)00029-X
extern: '1'
external_id:
  pmid:
  - '12615001'
fulldoi: https://doi.org/10.1016/S0168-9525(02)00029-X
intvolume: '        19'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 115 - 119
pmid: 1
publication: Trends in Genetics
publication_identifier:
  eissn:
  - 1362-4555
  issn:
  - 0168-9525
publication_status: published
publisher: Elsevier
publist_id: '6776'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Evolution of alternative splicing: Deletions, insertions and origin of functional
  parts of proteins from intron sequences'
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 19
year: '2003'
...
---
_id: '9455'
abstract:
- lang: eng
  text: Proteins of the ARGONAUTE family are important in diverse posttranscriptional
    RNA-mediated gene-silencing systems as well as in transcriptional gene silencing
    in Drosophila and fission yeast and in programmed DNA elimination in Tetrahymena.
    We cloned ARGONAUTE4 (AGO4) from a screen for mutants that suppress silencing
    of the Arabidopsis SUPERMAN(SUP) gene. The ago4-1 mutant reactivated silentSUP
    alleles and decreased CpNpG and asymmetric DNA methylation as well as histone
    H3 lysine-9 methylation. In addition,ago4-1 blocked histone and DNA methylation
    and the accumulation of 25-nucleotide small interfering RNAs (siRNAs) that correspond
    to the retroelement AtSN1. These results suggest that AGO4 and long siRNAs direct
    chromatin modifications, including histone methylation and non-CpG DNA methylation.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
- first_name: ' Xiaofeng'
  full_name: Cao,  Xiaofeng
  last_name: Cao
- first_name: Steven E.
  full_name: Jacobsen, Steven E.
  last_name: Jacobsen
citation:
  ama: Zilberman D, Cao  Xiaofeng, Jacobsen SE. ARGONAUTE4 control of locus-specific
    siRNA accumulation and DNA and histone methylation. <i>Science</i>. 2003;299(5607):716-719.
    doi:<a href="https://doi.org/10.1126/science.1079695">10.1126/science.1079695</a>
  apa: Zilberman, D., Cao,  Xiaofeng, &#38; Jacobsen, S. E. (2003). ARGONAUTE4 control
    of locus-specific siRNA accumulation and DNA and histone methylation. <i>Science</i>.
    American Association for the Advancement of Science. <a href="https://doi.org/10.1126/science.1079695">https://doi.org/10.1126/science.1079695</a>
  chicago: Zilberman, Daniel,  Xiaofeng Cao, and Steven E. Jacobsen. “ARGONAUTE4 Control
    of Locus-Specific SiRNA Accumulation and DNA and Histone Methylation.” <i>Science</i>.
    American Association for the Advancement of Science, 2003. <a href="https://doi.org/10.1126/science.1079695">https://doi.org/10.1126/science.1079695</a>.
  ieee: D. Zilberman,  Xiaofeng Cao, and S. E. Jacobsen, “ARGONAUTE4 control of locus-specific
    siRNA accumulation and DNA and histone methylation,” <i>Science</i>, vol. 299,
    no. 5607. American Association for the Advancement of Science, pp. 716–719, 2003.
  ista: Zilberman D, Cao  Xiaofeng, Jacobsen SE. 2003. ARGONAUTE4 control of locus-specific
    siRNA accumulation and DNA and histone methylation. Science. 299(5607), 716–719.
  mla: Zilberman, Daniel, et al. “ARGONAUTE4 Control of Locus-Specific SiRNA Accumulation
    and DNA and Histone Methylation.” <i>Science</i>, vol. 299, no. 5607, American
    Association for the Advancement of Science, 2003, pp. 716–19, doi:<a href="https://doi.org/10.1126/science.1079695">10.1126/science.1079695</a>.
  short: D. Zilberman,  Xiaofeng Cao, S.E. Jacobsen, Science 299 (2003) 716–719.
date_created: 2021-06-04T11:26:26Z
date_published: 2003-01-31T00:00:00Z
date_updated: 2021-12-14T08:43:30Z
day: '31'
department:
- _id: DaZi
doi: 10.1126/science.1079695
extern: '1'
external_id:
  pmid:
  - '12522258'
fulldoi: https://doi.org/10.1126/science.1079695
intvolume: '       299'
issue: '5607'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '01'
oa_version: None
page: 716-719
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone
  methylation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 299
year: '2003'
...
---
_id: '9495'
abstract:
- lang: eng
  text: RNA interference is a conserved process in which double-stranded RNA is processed
    into 21–25 nucleotide siRNAs that trigger posttranscriptional gene silencing.
    In addition, plants display a phenomenon termed RNA-directed DNA methylation (RdDM)
    in which DNA with sequence identity to silenced RNA is de novo methylated at its
    cytosine residues. This methylation is not only at canonical CpG sites but also
    at cytosines in CpNpG and asymmetric sequence contexts. In this report, we study
    the role of the DRM and CMT3 DNA methyltransferase genes in the initiation and
    maintenance of RdDM. Neither drm nor cmt3 mutants affected the maintenance of
    preestablished RNA-directed CpG methylation. However, drm mutants showed a nearly
    complete loss of asymmetric methylation and a partial loss of CpNpG methylation.
    The remaining asymmetric and CpNpG methylation was dependent on the activity of
    CMT3, showing that DRM and CMT3 act redundantly to maintain non-CpG methylation.
    These DNA methyltransferases appear to act downstream of siRNAs, since drm1 drm2
    cmt3 triple mutants show a lack of non-CpG methylation but elevated levels of
    siRNAs. Finally, we demonstrate that DRM activity is required for the initial
    establishment of RdDM in all sequence contexts including CpG, CpNpG, and asymmetric
    sites.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaofeng
  full_name: Cao, Xiaofeng
  last_name: Cao
- first_name: Werner
  full_name: Aufsatz, Werner
  last_name: Aufsatz
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
- first_name: M.Florian
  full_name: Mette, M.Florian
  last_name: Mette
- first_name: Michael S.
  full_name: Huang, Michael S.
  last_name: Huang
- first_name: Marjori
  full_name: Matzke, Marjori
  last_name: Matzke
- first_name: Steven E.
  full_name: Jacobsen, Steven E.
  last_name: Jacobsen
citation:
  ama: Cao X, Aufsatz W, Zilberman D, et al. Role of the DRM and CMT3 methyltransferases
    in RNA-directed DNA methylation. <i>Current Biology</i>. 2003;13(24):2212-2217.
    doi:<a href="https://doi.org/10.1016/j.cub.2003.11.052">10.1016/j.cub.2003.11.052</a>
  apa: Cao, X., Aufsatz, W., Zilberman, D., Mette, M. F., Huang, M. S., Matzke, M.,
    &#38; Jacobsen, S. E. (2003). Role of the DRM and CMT3 methyltransferases in RNA-directed
    DNA methylation. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2003.11.052">https://doi.org/10.1016/j.cub.2003.11.052</a>
  chicago: Cao, Xiaofeng, Werner Aufsatz, Daniel Zilberman, M.Florian Mette, Michael
    S. Huang, Marjori Matzke, and Steven E. Jacobsen. “Role of the DRM and CMT3 Methyltransferases
    in RNA-Directed DNA Methylation.” <i>Current Biology</i>. Elsevier, 2003. <a href="https://doi.org/10.1016/j.cub.2003.11.052">https://doi.org/10.1016/j.cub.2003.11.052</a>.
  ieee: X. Cao <i>et al.</i>, “Role of the DRM and CMT3 methyltransferases in RNA-directed
    DNA methylation,” <i>Current Biology</i>, vol. 13, no. 24. Elsevier, pp. 2212–2217,
    2003.
  ista: Cao X, Aufsatz W, Zilberman D, Mette MF, Huang MS, Matzke M, Jacobsen SE.
    2003. Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation.
    Current Biology. 13(24), 2212–2217.
  mla: Cao, Xiaofeng, et al. “Role of the DRM and CMT3 Methyltransferases in RNA-Directed
    DNA Methylation.” <i>Current Biology</i>, vol. 13, no. 24, Elsevier, 2003, pp.
    2212–17, doi:<a href="https://doi.org/10.1016/j.cub.2003.11.052">10.1016/j.cub.2003.11.052</a>.
  short: X. Cao, W. Aufsatz, D. Zilberman, M.F. Mette, M.S. Huang, M. Matzke, S.E.
    Jacobsen, Current Biology 13 (2003) 2212–2217.
date_created: 2021-06-07T10:43:02Z
date_published: 2003-12-16T00:00:00Z
date_updated: 2021-12-14T08:41:38Z
day: '16'
department:
- _id: DaZi
doi: 10.1016/j.cub.2003.11.052
extern: '1'
external_id:
  pmid:
  - '14680640'
fulldoi: https://doi.org/10.1016/j.cub.2003.11.052
intvolume: '        13'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cub.2003.11.052
month: '12'
oa: 1
oa_version: Published Version
page: 2212-2217
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 13
year: '2003'
...
---
OA_type: closed access
_id: '3139'
article_processing_charge: No
author:
- first_name: Hsiao
  full_name: Chen, Hsiao
  last_name: Chen
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Silvia
  full_name: Arber, Silvia
  last_name: Arber
- first_name: Eric
  full_name: Frank, Eric
  last_name: Frank
citation:
  ama: Chen H, Hippenmeyer S, Arber S, Frank E. Development of the monosynaptic stretch
    reflex circuit. <i>Current Opinion in Neurobiology</i>. 2003;13(1):96-102. doi:<a
    href="https://doi.org/10.1016/S0959-4388(03)00006-0">10.1016/S0959-4388(03)00006-0</a>
  apa: Chen, H., Hippenmeyer, S., Arber, S., &#38; Frank, E. (2003). Development of
    the monosynaptic stretch reflex circuit. <i>Current Opinion in Neurobiology</i>.
    Elsevier. <a href="https://doi.org/10.1016/S0959-4388(03)00006-0">https://doi.org/10.1016/S0959-4388(03)00006-0</a>
  chicago: Chen, Hsiao, Simon Hippenmeyer, Silvia Arber, and Eric Frank. “Development
    of the Monosynaptic Stretch Reflex Circuit.” <i>Current Opinion in Neurobiology</i>.
    Elsevier, 2003. <a href="https://doi.org/10.1016/S0959-4388(03)00006-0">https://doi.org/10.1016/S0959-4388(03)00006-0</a>.
  ieee: H. Chen, S. Hippenmeyer, S. Arber, and E. Frank, “Development of the monosynaptic
    stretch reflex circuit,” <i>Current Opinion in Neurobiology</i>, vol. 13, no.
    1. Elsevier, pp. 96–102, 2003.
  ista: Chen H, Hippenmeyer S, Arber S, Frank E. 2003. Development of the monosynaptic
    stretch reflex circuit. Current Opinion in Neurobiology. 13(1), 96–102.
  mla: Chen, Hsiao, et al. “Development of the Monosynaptic Stretch Reflex Circuit.”
    <i>Current Opinion in Neurobiology</i>, vol. 13, no. 1, Elsevier, 2003, pp. 96–102,
    doi:<a href="https://doi.org/10.1016/S0959-4388(03)00006-0">10.1016/S0959-4388(03)00006-0</a>.
  short: H. Chen, S. Hippenmeyer, S. Arber, E. Frank, Current Opinion in Neurobiology
    13 (2003) 96–102.
date_created: 2018-12-11T12:01:37Z
date_published: 2003-02-01T00:00:00Z
date_updated: 2026-05-22T08:40:52Z
day: '01'
doi: 10.1016/S0959-4388(03)00006-0
extern: '1'
external_id:
  pmid:
  - '12593987'
fulldoi: https://doi.org/10.1016/S0959-4388(03)00006-0
intvolume: '        13'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 96 - 102
pmid: 1
publication: Current Opinion in Neurobiology
publication_identifier:
  eissn:
  - 1873-6882
  issn:
  - 0959-4388
publication_status: published
publisher: Elsevier
publist_id: '3557'
status: public
title: Development of the monosynaptic stretch reflex circuit
type: review
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 13
year: '2003'
...
---
OA_type: closed access
_id: '3150'
abstract:
- lang: eng
  text: Tripartite G-protein-coupled receptors (GPCRs) represent one of the largest
    groups of signal transducers, transmitting signals from hormones, neuropeptides,
    odorants, food and light. Ligand-bound receptors catalyse GDP/GTP exchange on
    the G-protein α-subunit (Gα), leading to α-GTP separation from the βγ subunits
    and pathway activation. Activating mutations in the receptors or G proteins underlie
    many human diseases, including some cancers, dwarfism and premature puberty. Regulators
    of G-protein signalling (RGS proteins) are known to modulate the level and duration
    of ligand-induced signalling by accelerating the intrinsic GTPase activity of
    the Gα subunit, and thus reformation of the inactive GDP-bound Gα. Here we find
    that even in the absence of receptor, mutation of the RGS family member Sst2 (refs
    6-9) permits spontaneous activation of the G-protein-coupled mating pathway in
    Saccharomyces cerevisiae at levels normally seen only in the presence of ligand.
    Our work demonstrates the occurence of spontaneous tripartite G-protein signalling
    in vivo and identifies a requirement for RGS proteins in preventing such receptor-independent
    activation.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: David
  full_name: Drubin, David
  last_name: Drubin
citation:
  ama: Siekhaus DE, Drubin D. Spontaneous receptor-independent heterotrimeric G-protein
    signalling in an RGS mutant. <i>Nature Cell Biology</i>. 2003;5(3):231-235. doi:<a
    href="https://doi.org/10.1038/ncb941">10.1038/ncb941</a>
  apa: Siekhaus, D. E., &#38; Drubin, D. (2003). Spontaneous receptor-independent
    heterotrimeric G-protein signalling in an RGS mutant. <i>Nature Cell Biology</i>.
    Springer Nature. <a href="https://doi.org/10.1038/ncb941">https://doi.org/10.1038/ncb941</a>
  chicago: Siekhaus, Daria E, and David Drubin. “Spontaneous Receptor-Independent
    Heterotrimeric G-Protein Signalling in an RGS Mutant.” <i>Nature Cell Biology</i>.
    Springer Nature, 2003. <a href="https://doi.org/10.1038/ncb941">https://doi.org/10.1038/ncb941</a>.
  ieee: D. E. Siekhaus and D. Drubin, “Spontaneous receptor-independent heterotrimeric
    G-protein signalling in an RGS mutant,” <i>Nature Cell Biology</i>, vol. 5, no.
    3. Springer Nature, pp. 231–235, 2003.
  ista: Siekhaus DE, Drubin D. 2003. Spontaneous receptor-independent heterotrimeric
    G-protein signalling in an RGS mutant. Nature Cell Biology. 5(3), 231–235.
  mla: Siekhaus, Daria E., and David Drubin. “Spontaneous Receptor-Independent Heterotrimeric
    G-Protein Signalling in an RGS Mutant.” <i>Nature Cell Biology</i>, vol. 5, no.
    3, Springer Nature, 2003, pp. 231–35, doi:<a href="https://doi.org/10.1038/ncb941">10.1038/ncb941</a>.
  short: D.E. Siekhaus, D. Drubin, Nature Cell Biology 5 (2003) 231–235.
date_created: 2018-12-11T12:01:41Z
date_published: 2003-03-01T00:00:00Z
date_updated: 2026-05-21T13:51:51Z
day: '01'
doi: 10.1038/ncb941
extern: '1'
external_id:
  pmid:
  - '12598904 '
fulldoi: https://doi.org/10.1038/ncb941
intvolume: '         5'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 231 - 235
pmid: 1
publication: Nature Cell Biology
publication_identifier:
  eissn:
  - 1476-4679
  issn:
  - 1465-7392
publication_status: published
publisher: Springer Nature
publist_id: '3544'
quality_controlled: '1'
status: public
title: Spontaneous receptor-independent heterotrimeric G-protein signalling in an
  RGS mutant
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 5
year: '2003'
...
---
OA_type: closed access
_id: '3151'
abstract:
- lang: eng
  text: Biosynthesis of most peptide hormones and neuropeptides requires proteolytic
    excision of the active peptide from inactive proprotein precursors, an activity
    carried out by subtilisin-like proprotein convertases (SPCs) in constitutive or
    regulated secretory pathways. The Drosophila amontillado (amon) gene encodes a
    homolog of the mammalian PC2 protein, an SPC that functions in the regulated secretory
    pathway in neuroendocrine tissues. We have identified amon mutants by isolating
    ethylmethanesulfonate (EMS)-induced lethal and visible mutations that define two
    complementation groups in the amon interval at 97D1 of the third chromosome. DNA
    sequencing identified the amon complementation group and the DNA sequence change
    for each of the nine amon alleles isolated. amon mutants display partial embryonic
    lethality, are defective in larval growth, and arrest during the first to second
    instar larval molt. Mutant larvae can be rescued by heat-shock-induced expression
    of the amon protein. Rescued larvae arrest at the subsequent larval molt, suggesting
    that amon is also required for the second to third instar larval molt. Our data
    indicate that the amon proprotein convertase is required during embryogenesis
    and larval development in Drosophila and support the hypothesis that AMON acts
    to proteolytically process peptide hormones that regulate hatching, larval growth,
    and larval ecdysis.
article_processing_charge: No
article_type: original
author:
- first_name: Lowell
  full_name: Rayburn, Lowell
  last_name: Rayburn
- first_name: Holly
  full_name: Gooding, Holly
  last_name: Gooding
- first_name: Semil
  full_name: Choksi, Semil
  last_name: Choksi
- first_name: Dhea
  full_name: Maloney, Dhea
  last_name: Maloney
- first_name: Ambrose
  full_name: Kidd, Ambrose
  last_name: Kidd
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: Michael
  full_name: Bender, Michael
  last_name: Bender
citation:
  ama: Rayburn L, Gooding H, Choksi S, et al. Amontillado, the Drosophila homolog
    of the prohormone processing protease PC2, is required during embryogenesis and
    early larval development. <i>Genetics</i>. 2003;163(1):227-237. doi:<a href="https://doi.org/10.1093/genetics/163.1.227">10.1093/genetics/163.1.227</a>
  apa: Rayburn, L., Gooding, H., Choksi, S., Maloney, D., Kidd, A., Siekhaus, D. E.,
    &#38; Bender, M. (2003). Amontillado, the Drosophila homolog of the prohormone
    processing protease PC2, is required during embryogenesis and early larval development.
    <i>Genetics</i>. Oxford Academic. <a href="https://doi.org/10.1093/genetics/163.1.227">https://doi.org/10.1093/genetics/163.1.227</a>
  chicago: Rayburn, Lowell, Holly Gooding, Semil Choksi, Dhea Maloney, Ambrose Kidd,
    Daria E Siekhaus, and Michael Bender. “Amontillado, the Drosophila Homolog of
    the Prohormone Processing Protease PC2, Is Required during Embryogenesis and Early
    Larval Development.” <i>Genetics</i>. Oxford Academic, 2003. <a href="https://doi.org/10.1093/genetics/163.1.227">https://doi.org/10.1093/genetics/163.1.227</a>.
  ieee: L. Rayburn <i>et al.</i>, “Amontillado, the Drosophila homolog of the prohormone
    processing protease PC2, is required during embryogenesis and early larval development,”
    <i>Genetics</i>, vol. 163, no. 1. Oxford Academic, pp. 227–237, 2003.
  ista: Rayburn L, Gooding H, Choksi S, Maloney D, Kidd A, Siekhaus DE, Bender M.
    2003. Amontillado, the Drosophila homolog of the prohormone processing protease
    PC2, is required during embryogenesis and early larval development. Genetics.
    163(1), 227–237.
  mla: Rayburn, Lowell, et al. “Amontillado, the Drosophila Homolog of the Prohormone
    Processing Protease PC2, Is Required during Embryogenesis and Early Larval Development.”
    <i>Genetics</i>, vol. 163, no. 1, Oxford Academic, 2003, pp. 227–37, doi:<a href="https://doi.org/10.1093/genetics/163.1.227">10.1093/genetics/163.1.227</a>.
  short: L. Rayburn, H. Gooding, S. Choksi, D. Maloney, A. Kidd, D.E. Siekhaus, M.
    Bender, Genetics 163 (2003) 227–237.
date_created: 2018-12-11T12:01:41Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2026-05-22T08:38:04Z
day: '01'
doi: 10.1093/genetics/163.1.227
extern: '1'
external_id:
  pmid:
  - '12586710'
fulldoi: https://doi.org/10.1093/genetics/163.1.227
intvolume: '       163'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 227 - 237
pmid: 1
publication: Genetics
publication_identifier:
  eissn:
  - 1943-2631
  issn:
  - 0016-6731
publication_status: published
publisher: Oxford Academic
publist_id: '3545'
quality_controlled: '1'
status: public
title: Amontillado, the Drosophila homolog of the prohormone processing protease PC2,
  is required during embryogenesis and early larval development
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 163
year: '2003'
...
---
OA_place: repository
OA_type: green
_id: '3171'
abstract:
- lang: eng
  text: 'Reconstructing a 3-D scene from more than one camera is a classical problem
    in computer vision. One of the major sources of difficulty is the fact that not
    all scene elements are visible from all cameras. In the last few years, two promising
    approaches have been developed 11,12 that formulate the scene reconstruction problem
    in terms of energy minimization, and minimize the energy using graph cuts. These
    energy minimization approaches treat the input images symmetrically, handle visibility
    constraints correctly, and allow spatial smoothness to be enforced. However, these
    algorithm propose different problem formulations, and handle a limited class of
    smoothness terms. One algorithm 11 uses a problem formulation that is restricted
    to two-camera stereo, and imposes smoothness between a pair of cameras. The other
    algorithm 12 can handle an arbitrary number of cameras, but imposes smoothness
    only with respect to a single camera. In this paper we give a more general energy
    minimization formulation for the problem, which allows a larger class of spatial
    smoothness constraints. We show that our formulation includes both of the previous
    approaches as special cases, as well as permitting new energy functions. Experimental
    results on real data with ground truth are also included. '
alternative_title:
- Energy Minimization Methods in Computer Vision and Pattern Recognition
article_processing_charge: No
author:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Ramin
  full_name: Zabih, Ramin
  last_name: Zabih
- first_name: Steven
  full_name: Gortler, Steven
  last_name: Gortler
citation:
  ama: 'Kolmogorov V, Zabih R, Gortler S. Generalized multi camera scene reconstruction
    using graph cuts. In: <i>4th International Workshop</i>. Vol 2683. Springer Nature;
    2003:501-516. doi:<a href="https://doi.org/10.1007/978-3-540-45063-4_32">10.1007/978-3-540-45063-4_32</a>'
  apa: 'Kolmogorov, V., Zabih, R., &#38; Gortler, S. (2003). Generalized multi camera
    scene reconstruction using graph cuts. In <i>4th International Workshop</i> (Vol.
    2683, pp. 501–516). Lisbon, Portugal: Springer Nature. <a href="https://doi.org/10.1007/978-3-540-45063-4_32">https://doi.org/10.1007/978-3-540-45063-4_32</a>'
  chicago: Kolmogorov, Vladimir, Ramin Zabih, and Steven Gortler. “Generalized Multi
    Camera Scene Reconstruction Using Graph Cuts.” In <i>4th International Workshop</i>,
    2683:501–16. Springer Nature, 2003. <a href="https://doi.org/10.1007/978-3-540-45063-4_32">https://doi.org/10.1007/978-3-540-45063-4_32</a>.
  ieee: V. Kolmogorov, R. Zabih, and S. Gortler, “Generalized multi camera scene reconstruction
    using graph cuts,” in <i>4th International Workshop</i>, Lisbon, Portugal, 2003,
    vol. 2683, pp. 501–516.
  ista: 'Kolmogorov V, Zabih R, Gortler S. 2003. Generalized multi camera scene reconstruction
    using graph cuts. 4th International Workshop. EMMCVPR: Energy Minimization Methods
    in Computer Vision and Pattern Recognition, Energy Minimization Methods in Computer
    Vision and Pattern Recognition, vol. 2683, 501–516.'
  mla: Kolmogorov, Vladimir, et al. “Generalized Multi Camera Scene Reconstruction
    Using Graph Cuts.” <i>4th International Workshop</i>, vol. 2683, Springer Nature,
    2003, pp. 501–16, doi:<a href="https://doi.org/10.1007/978-3-540-45063-4_32">10.1007/978-3-540-45063-4_32</a>.
  short: V. Kolmogorov, R. Zabih, S. Gortler, in:, 4th International Workshop, Springer
    Nature, 2003, pp. 501–516.
conference:
  end_date: 2003-07-09
  location: Lisbon, Portugal
  name: 'EMMCVPR: Energy Minimization Methods in Computer Vision and Pattern Recognition'
  start_date: 2003-07-07
date_created: 2018-12-11T12:01:48Z
date_published: 2003-06-26T00:00:00Z
date_updated: 2026-05-21T13:04:17Z
day: '26'
doi: 10.1007/978-3-540-45063-4_32
extern: '1'
fulldoi: https://doi.org/10.1007/978-3-540-45063-4_32
intvolume: '      2683'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.cs.cornell.edu/~rdz/Papers/KZG-EMMCVPR03.pdf
month: '06'
oa: 1
oa_version: Preprint
page: 501 - 516
publication: 4th International Workshop
publication_identifier:
  eisbn:
  - '9783540450634'
  isbn:
  - '9783540404989'
publication_status: published
publisher: Springer Nature
publist_id: '3512'
quality_controlled: '1'
status: public
title: Generalized multi camera scene reconstruction using graph cuts
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 2683
year: '2003'
...
---
OA_place: publisher
OA_type: free access
_id: '3209'
abstract:
- lang: eng
  text: We show that the fixed alphabet shortest common supersequence (SCS) and the
    fixed alphabet longest common subsequence (LCS) problems parameterized in the
    number of strings are W[1]-hard. Unless W[1]=FPT, this rules out the existence
    of algorithms with time complexity of O(f(k)nα) for those problems. Here n is
    the size of the problem instance, α is constant, k is the number of strings and
    f is any function of k. The fixed alphabet version of the LCS problem is of particular
    interest considering the importance of sequence comparison (e.g. multiple sequence
    alignment) in the fixed length alphabet world of DNA and protein sequences.
article_processing_charge: No
article_type: original
author:
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: Pietrzak KZ. On the parameterized complexity of the fixed alphabet shortest
    common supersequence and longest common subsequence problems. <i>Journal of Computer
    and System Sciences</i>. 2003;67(4):757-771. doi:<a href="https://doi.org/10.1016/S0022-0000(03)00078-3">10.1016/S0022-0000(03)00078-3</a>
  apa: Pietrzak, K. Z. (2003). On the parameterized complexity of the fixed alphabet
    shortest common supersequence and longest common subsequence problems. <i>Journal
    of Computer and System Sciences</i>. Elsevier. <a href="https://doi.org/10.1016/S0022-0000(03)00078-3">https://doi.org/10.1016/S0022-0000(03)00078-3</a>
  chicago: Pietrzak, Krzysztof Z. “On the Parameterized Complexity of the Fixed Alphabet
    Shortest Common Supersequence and Longest Common Subsequence Problems.” <i>Journal
    of Computer and System Sciences</i>. Elsevier, 2003. <a href="https://doi.org/10.1016/S0022-0000(03)00078-3">https://doi.org/10.1016/S0022-0000(03)00078-3</a>.
  ieee: K. Z. Pietrzak, “On the parameterized complexity of the fixed alphabet shortest
    common supersequence and longest common subsequence problems,” <i>Journal of Computer
    and System Sciences</i>, vol. 67, no. 4. Elsevier, pp. 757–771, 2003.
  ista: Pietrzak KZ. 2003. On the parameterized complexity of the fixed alphabet shortest
    common supersequence and longest common subsequence problems. Journal of Computer
    and System Sciences. 67(4), 757–771.
  mla: Pietrzak, Krzysztof Z. “On the Parameterized Complexity of the Fixed Alphabet
    Shortest Common Supersequence and Longest Common Subsequence Problems.” <i>Journal
    of Computer and System Sciences</i>, vol. 67, no. 4, Elsevier, 2003, pp. 757–71,
    doi:<a href="https://doi.org/10.1016/S0022-0000(03)00078-3">10.1016/S0022-0000(03)00078-3</a>.
  short: K.Z. Pietrzak, Journal of Computer and System Sciences 67 (2003) 757–771.
date_created: 2018-12-11T12:02:01Z
date_published: 2003-12-01T00:00:00Z
date_updated: 2026-05-21T11:50:33Z
day: '01'
doi: 10.1016/S0022-0000(03)00078-3
extern: '1'
fulldoi: https://doi.org/10.1016/S0022-0000(03)00078-3
intvolume: '        67'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/S0022-0000(03)00078-3
month: '12'
oa: 1
oa_version: Accepted Version
page: 757 - 771
publication: Journal of Computer and System Sciences
publication_status: published
publisher: Elsevier
publist_id: '3472'
quality_controlled: '1'
status: public
title: On the parameterized complexity of the fixed alphabet shortest common supersequence
  and longest common subsequence problems
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 67
year: '2003'
...
