[{"status":"public","issue":"1","day":"01","publisher":"Internet Mathematics","type":"journal_article","date_updated":"2024-11-06T08:13:59Z","oa_version":"Published Version","year":"2004","date_published":"2004-01-01T00:00:00Z","page":"115-123","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"01","title":"Algorithmic challenges in web search engines","_id":"11762","citation":{"ieee":"M. Henzinger, “Algorithmic challenges in web search engines,” <i>Internet Mathematics</i>, vol. 1, no. 1. Internet Mathematics, pp. 115–123, 2004.","mla":"Henzinger, Monika. “Algorithmic Challenges in Web Search Engines.” <i>Internet Mathematics</i>, vol. 1, no. 1, Internet Mathematics, 2004, pp. 115–23, doi:<a href=\"https://doi.org/10.1080/15427951.2004.10129079\">10.1080/15427951.2004.10129079</a>.","short":"M. Henzinger, Internet Mathematics 1 (2004) 115–123.","ista":"Henzinger M. 2004. Algorithmic challenges in web search engines. Internet Mathematics. 1(1), 115–123.","chicago":"Henzinger, Monika. “Algorithmic Challenges in Web Search Engines.” <i>Internet Mathematics</i>. Internet Mathematics, 2004. <a href=\"https://doi.org/10.1080/15427951.2004.10129079\">https://doi.org/10.1080/15427951.2004.10129079</a>.","apa":"Henzinger, M. (2004). Algorithmic challenges in web search engines. <i>Internet Mathematics</i>. Internet Mathematics. <a href=\"https://doi.org/10.1080/15427951.2004.10129079\">https://doi.org/10.1080/15427951.2004.10129079</a>","ama":"Henzinger M. Algorithmic challenges in web search engines. <i>Internet Mathematics</i>. 2004;1(1):115-123. doi:<a href=\"https://doi.org/10.1080/15427951.2004.10129079\">10.1080/15427951.2004.10129079</a>"},"article_processing_charge":"No","article_type":"original","doi":"10.1080/15427951.2004.10129079","publication_identifier":{"eissn":["1944-9488"],"issn":["1542-7951"]},"oa":1,"main_file_link":[{"url":"https://doi.org/10.1080/15427951.2004.10129079","open_access":"1"}],"intvolume":"         1","publication":"Internet Mathematics","scopus_import":"1","author":[{"first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H","last_name":"Henzinger","orcid":"0000-0002-5008-6530"}],"quality_controlled":"1","volume":1,"abstract":[{"lang":"eng","text":"In this paper, we describe six algorithmic problems that arise in web search engines and that are not or only partially solved: (1) Uniformly sampling of web pages; (2) modeling the web graph; (3) finding duplicate hosts; (4) finding top gainers and losers in data streams; (5) finding large dense bipartite graphs; and (6) understanding how eigenvectors partition the web."}],"publication_status":"published","language":[{"iso":"eng"}],"date_created":"2022-08-08T11:55:53Z"},{"publication_status":"published","date_created":"2022-08-11T12:38:58Z","doi":"10.1007/978-3-540-27836-8_2","language":[{"iso":"eng"}],"alternative_title":["LNCS"],"volume":3142,"_id":"11800","title":"The past, present, and future of web search engines","quality_controlled":"1","month":"07","article_processing_charge":"No","abstract":[{"text":"Web search engines have emerged as one of the central applications on the Internet. In fact, search has become one of the most important activities that people engage in on the the Internet. Even beyond becoming the number one source of information, a growing number of businesses are depending on web search engines for customer acquisition.\r\n\r\nThe first generation of web search engines used text-only retrieval techniques. Google revolutionized the field by deploying the PageRank technology – an eigenvector-based analysis of the hyperlink structure – to analyze the web in order to produce relevant results. Moving forward, our goal is to achieve a better understanding of a page with a view towards producing even more relevant results.","lang":"eng"}],"conference":{"name":"ICALP: International Colloquium on Automata, Languages, and Programming","start_date":"2004-07-12","location":"Turku, Finland","end_date":"2004-07-16"},"citation":{"ieee":"M. Henzinger, “The past, present, and future of web search engines,” in <i>31st International Colloquium on Automata, Languages and Programming</i>, Turku, Finland, 2004, vol. 3142, p. 3.","short":"M. Henzinger, in:, 31st International Colloquium on Automata, Languages and Programming, Springer Nature, 2004, p. 3.","mla":"Henzinger, Monika. “The Past, Present, and Future of Web Search Engines.” <i>31st International Colloquium on Automata, Languages and Programming</i>, vol. 3142, Springer Nature, 2004, p. 3, doi:<a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">10.1007/978-3-540-27836-8_2</a>.","chicago":"Henzinger, Monika. “The Past, Present, and Future of Web Search Engines.” In <i>31st International Colloquium on Automata, Languages and Programming</i>, 3142:3. Springer Nature, 2004. <a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">https://doi.org/10.1007/978-3-540-27836-8_2</a>.","ista":"Henzinger M. 2004. The past, present, and future of web search engines. 31st International Colloquium on Automata, Languages and Programming. ICALP: International Colloquium on Automata, Languages, and Programming, LNCS, vol. 3142, 3.","ama":"Henzinger M. The past, present, and future of web search engines. In: <i>31st International Colloquium on Automata, Languages and Programming</i>. Vol 3142. Springer Nature; 2004:3. doi:<a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">10.1007/978-3-540-27836-8_2</a>","apa":"Henzinger, M. (2004). The past, present, and future of web search engines. In <i>31st International Colloquium on Automata, Languages and Programming</i> (Vol. 3142, p. 3). Turku, Finland: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">https://doi.org/10.1007/978-3-540-27836-8_2</a>"},"date_published":"2004-07-01T00:00:00Z","year":"2004","oa_version":"None","date_updated":"2024-11-06T08:14:51Z","publication":"31st International Colloquium on Automata, Languages and Programming","author":[{"orcid":"0000-0002-5008-6530","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H","last_name":"Henzinger","full_name":"Henzinger, Monika H"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","extern":"1","intvolume":"      3142","page":"3","status":"public","publication_identifier":{"eissn":["1611-3349"],"issn":["0302-9743"]},"day":"01","type":"conference","publisher":"Springer Nature"},{"publication_status":"published","alternative_title":["LNCS"],"language":[{"iso":"eng"}],"doi":"10.1007/978-3-540-30140-0_2","date_created":"2022-08-11T13:18:05Z","month":"09","title":"Algorithmic aspects of web search engines","quality_controlled":"1","_id":"11801","volume":3221,"citation":{"ieee":"M. Henzinger, “Algorithmic aspects of web search engines,” in <i>2th Annual European Symposium on Algorithms</i>, Bergen, Norway, 2004, vol. 3221, p. 3.","mla":"Henzinger, Monika. “Algorithmic Aspects of Web Search Engines.” <i>2th Annual European Symposium on Algorithms</i>, vol. 3221, Springer Nature, 2004, p. 3, doi:<a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">10.1007/978-3-540-30140-0_2</a>.","short":"M. Henzinger, in:, 2th Annual European Symposium on Algorithms, Springer Nature, 2004, p. 3.","chicago":"Henzinger, Monika. “Algorithmic Aspects of Web Search Engines.” In <i>2th Annual European Symposium on Algorithms</i>, 3221:3. Springer Nature, 2004. <a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">https://doi.org/10.1007/978-3-540-30140-0_2</a>.","ista":"Henzinger M. 2004. Algorithmic aspects of web search engines. 2th Annual European Symposium on Algorithms. ESA: European Symposium on Algorithms, LNCS, vol. 3221, 3.","ama":"Henzinger M. Algorithmic aspects of web search engines. In: <i>2th Annual European Symposium on Algorithms</i>. Vol 3221. Springer Nature; 2004:3. doi:<a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">10.1007/978-3-540-30140-0_2</a>","apa":"Henzinger, M. (2004). Algorithmic aspects of web search engines. In <i>2th Annual European Symposium on Algorithms</i> (Vol. 3221, p. 3). Bergen, Norway: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">https://doi.org/10.1007/978-3-540-30140-0_2</a>"},"conference":{"start_date":"2004-09-14","name":"ESA: European Symposium on Algorithms","end_date":"2004-09-17","location":"Bergen, Norway"},"article_processing_charge":"No","abstract":[{"lang":"eng","text":"Web search engines have emerged as one of the central applications on the internet. In fact, search has become one of the most important activities that people engage in on the Internet. Even beyond becoming the number one source of information, a growing number of businesses are depending on web search engines for customer acquisition. In this talk I will brief review the history of web search engines: The first generation of web search engines used text-only retrieval techniques. Google revolutionized the field by deploying the PageRank technology – an eigenvector-based analysis of the hyperlink structure- to analyze the web in order to produce relevant results. Moving forward, our goal is to achieve a better understanding of a page with a view towards producing even more relevant results.\r\n\r\nGoogle is powered by a large number of PCs. Using this infrastructure and striving to be as efficient as possible poses challenging systems problems but also various algorithmic challenges. I will discuss some of them in my talk."}],"date_updated":"2024-11-06T11:55:33Z","year":"2004","oa_version":"None","date_published":"2004-09-01T00:00:00Z","page":"3","intvolume":"      3221","extern":"1","author":[{"first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H","last_name":"Henzinger","orcid":"0000-0002-5008-6530"}],"scopus_import":"1","publication":"2th Annual European Symposium on Algorithms","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"isbn":[" 3540230254"],"issn":["0302-9743"],"eissn":["1611-3349"]},"status":"public","publisher":"Springer Nature","day":"01","type":"conference"},{"year":"2004","oa_version":"None","date_updated":"2024-11-06T11:59:44Z","date_published":"2004-01-01T00:00:00Z","extern":"1","page":"23 - 26","intvolume":"      5296","publication":"SPIE Proceedings","author":[{"orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H"}],"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["0277-786X"]},"status":"public","day":"01","publisher":"Society of Photo-Optical Instrumentation Engineers","type":"conference","publication_status":"published","doi":"10.1117/12.537534","language":[{"iso":"eng"}],"date_created":"2022-08-16T08:46:41Z","quality_controlled":"1","title":"The past, present, and future of web information retrieval","month":"01","volume":5296,"_id":"11859","citation":{"ieee":"M. Henzinger, “The past, present, and future of web information retrieval,” in <i>SPIE Proceedings</i>, San Jose, CA, United States, 2004, vol. 5296, pp. 23–26.","short":"M. Henzinger, in:, SPIE Proceedings, Society of Photo-Optical Instrumentation Engineers, 2004, pp. 23–26.","mla":"Henzinger, Monika. “The Past, Present, and Future of Web Information Retrieval.” <i>SPIE Proceedings</i>, vol. 5296, Society of Photo-Optical Instrumentation Engineers, 2004, pp. 23–26, doi:<a href=\"https://doi.org/10.1117/12.537534\">10.1117/12.537534</a>.","chicago":"Henzinger, Monika. “The Past, Present, and Future of Web Information Retrieval.” In <i>SPIE Proceedings</i>, 5296:23–26. Society of Photo-Optical Instrumentation Engineers, 2004. <a href=\"https://doi.org/10.1117/12.537534\">https://doi.org/10.1117/12.537534</a>.","ista":"Henzinger M. 2004. The past, present, and future of web information retrieval. SPIE Proceedings. Document Recognition and Retrieval XI vol. 5296, 23–26.","ama":"Henzinger M. The past, present, and future of web information retrieval. In: <i>SPIE Proceedings</i>. Vol 5296. Society of Photo-Optical Instrumentation Engineers; 2004:23-26. doi:<a href=\"https://doi.org/10.1117/12.537534\">10.1117/12.537534</a>","apa":"Henzinger, M. (2004). The past, present, and future of web information retrieval. In <i>SPIE Proceedings</i> (Vol. 5296, pp. 23–26). San Jose, CA, United States: Society of Photo-Optical Instrumentation Engineers. <a href=\"https://doi.org/10.1117/12.537534\">https://doi.org/10.1117/12.537534</a>"},"abstract":[{"lang":"eng","text":"In this article we describe the approach taken by the first web search engines, discuss the state of the art, and present some of the challenges for the future."}],"article_processing_charge":"No","conference":{"name":"Document Recognition and Retrieval XI","start_date":"2004-01-21","location":"San Jose, CA, United States","end_date":"2004-01-22"}},{"status":"public","type":"journal_article","day":"06","publisher":"Proceedings of the National Academy of Sciences","issue":"suppl_1","date_published":"2004-04-06T00:00:00Z","year":"2004","oa_version":"Published Version","date_updated":"2024-11-06T12:00:20Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","page":"5186-5191","_id":"11877","title":"Extracting knowledge from the World Wide Web","month":"04","article_processing_charge":"No","citation":{"mla":"Henzinger, Monika, and Steve Lawrence. “Extracting Knowledge from the World Wide Web.” <i>Proceedings of the National Academy of Sciences</i>, vol. 101, no. suppl_1, Proceedings of the National Academy of Sciences, 2004, pp. 5186–91, doi:<a href=\"https://doi.org/10.1073/pnas.0307528100\">10.1073/pnas.0307528100</a>.","short":"M. Henzinger, S. Lawrence, Proceedings of the National Academy of Sciences 101 (2004) 5186–5191.","ieee":"M. Henzinger and S. Lawrence, “Extracting knowledge from the World Wide Web,” <i>Proceedings of the National Academy of Sciences</i>, vol. 101, no. suppl_1. Proceedings of the National Academy of Sciences, pp. 5186–5191, 2004.","apa":"Henzinger, M., &#38; Lawrence, S. (2004). Extracting knowledge from the World Wide Web. <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.0307528100\">https://doi.org/10.1073/pnas.0307528100</a>","ama":"Henzinger M, Lawrence S. Extracting knowledge from the World Wide Web. <i>Proceedings of the National Academy of Sciences</i>. 2004;101(suppl_1):5186-5191. doi:<a href=\"https://doi.org/10.1073/pnas.0307528100\">10.1073/pnas.0307528100</a>","ista":"Henzinger M, Lawrence S. 2004. Extracting knowledge from the World Wide Web. Proceedings of the National Academy of Sciences. 101(suppl_1), 5186–5191.","chicago":"Henzinger, Monika, and Steve Lawrence. “Extracting Knowledge from the World Wide Web.” <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences, 2004. <a href=\"https://doi.org/10.1073/pnas.0307528100\">https://doi.org/10.1073/pnas.0307528100</a>."},"doi":"10.1073/pnas.0307528100","article_type":"original","pmid":1,"oa":1,"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387294/"}],"publication":"Proceedings of the National Academy of Sciences","author":[{"first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H","last_name":"Henzinger","orcid":"0000-0002-5008-6530"},{"full_name":"Lawrence, Steve","last_name":"Lawrence","first_name":"Steve"}],"scopus_import":"1","intvolume":"       101","volume":101,"quality_controlled":"1","abstract":[{"text":"The World Wide Web provides a unprecedented opportunity to automatically analyze a large sample of interests and activity in the world. We discuss methods for extracting knowledge from the web by randomly sampling and analyzing hosts and pages, and by analyzing the link structure of the web and how links accumulate over time. A variety of interesting and valuable information can be extracted, such as the distribution of web pages over domains, the distribution of interest in different areas, communities related to different topics, the nature of competition in different categories of sites, and the degree of communication between different communities or countries.","lang":"eng"}],"publication_status":"published","external_id":{"pmid":["14745041"]},"date_created":"2022-08-16T13:06:10Z","language":[{"iso":"eng"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"153-158","extern":"1","date_published":"2004-01-01T00:00:00Z","date_updated":"2023-05-08T10:58:29Z","year":"2004","oa_version":"None","issue":"2","type":"journal_article","publisher":"Informa UK Limited","status":"public","article_type":"original","doi":"10.1080/10425170410001667348","article_processing_charge":"No","citation":{"short":"Z. Liao, M. Chen, Y. Gong, L. Guo, Q. Tan, X. Feng, X. Sun, F. Tan, K. Tang, DNA Sequence 15 (2004) 153–158.","mla":"Liao, Zhihua, et al. “A New Geranylgeranyl Diphosphate Synthase Gene from Ginkgo Biloba, Which Intermediates the Biosynthesis of the Key Precursor for Ginkgolides.” <i>DNA Sequence</i>, vol. 15, no. 2, Informa UK Limited, 2004, pp. 153–58, doi:<a href=\"https://doi.org/10.1080/10425170410001667348\">10.1080/10425170410001667348</a>.","ieee":"Z. Liao <i>et al.</i>, “A new geranylgeranyl Diphosphate synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides,” <i>DNA Sequence</i>, vol. 15, no. 2. Informa UK Limited, pp. 153–158, 2004.","ama":"Liao Z, Chen M, Gong Y, et al. A new geranylgeranyl Diphosphate synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides. <i>DNA Sequence</i>. 2004;15(2):153-158. doi:<a href=\"https://doi.org/10.1080/10425170410001667348\">10.1080/10425170410001667348</a>","apa":"Liao, Z., Chen, M., Gong, Y., Guo, L., Tan, Q., Feng, X., … Tang, K. (2004). A new geranylgeranyl Diphosphate synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides. <i>DNA Sequence</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/10425170410001667348\">https://doi.org/10.1080/10425170410001667348</a>","chicago":"Liao, Zhihua, Min Chen, Yifu Gong, Liang Guo, Qiumin Tan, Xiaoqi Feng, Xiaofen Sun, Feng Tan, and Kexuan Tang. “A New Geranylgeranyl Diphosphate Synthase Gene from Ginkgo Biloba, Which Intermediates the Biosynthesis of the Key Precursor for Ginkgolides.” <i>DNA Sequence</i>. Informa UK Limited, 2004. <a href=\"https://doi.org/10.1080/10425170410001667348\">https://doi.org/10.1080/10425170410001667348</a>.","ista":"Liao Z, Chen M, Gong Y, Guo L, Tan Q, Feng X, Sun X, Tan F, Tang K. 2004. A new geranylgeranyl Diphosphate synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides. DNA Sequence. 15(2), 153–158."},"_id":"12203","title":"A new geranylgeranyl Diphosphate synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides","author":[{"full_name":"Liao, Zhihua","last_name":"Liao","first_name":"Zhihua"},{"full_name":"Chen, Min","last_name":"Chen","first_name":"Min"},{"full_name":"Gong, Yifu","last_name":"Gong","first_name":"Yifu"},{"last_name":"Guo","full_name":"Guo, Liang","first_name":"Liang"},{"full_name":"Tan, Qiumin","last_name":"Tan","first_name":"Qiumin"},{"orcid":"0000-0002-4008-1234","full_name":"Feng, Xiaoqi","last_name":"Feng","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","first_name":"Xiaoqi"},{"first_name":"Xiaofen","last_name":"Sun","full_name":"Sun, Xiaofen"},{"first_name":"Feng","last_name":"Tan","full_name":"Tan, Feng"},{"last_name":"Tang","full_name":"Tang, Kexuan","first_name":"Kexuan"}],"publication":"DNA Sequence","keyword":["Endocrinology","Genetics","Molecular Biology","Biochemistry"],"scopus_import":"1","intvolume":"        15","pmid":1,"acknowledgement":"This study was financially supported by China National High-Tech “863” Program. The authors are very thankful to Dr Li Wang (School of Life Sciences, Fudan University, Shanghai, China) for her kind help with constructing the phylogenetic tree.","publication_identifier":{"issn":["1042-5179"]},"date_created":"2023-01-16T09:24:50Z","external_id":{"pmid":["15352294"]},"department":[{"_id":"XiFe"}],"language":[{"iso":"eng"}],"publication_status":"published","abstract":[{"text":"Geranylgeranyl diphosphate synthase (GGPPS, EC: 2.5.1.29) catalyzes the biosynthesis of geranylgeranyl diphosphate (GGPP), which is a key precursor for ginkgolide biosynthesis. Here we reported for the first time the cloning of a new full-length cDNA encoding GGPPS from the living fossil plant Ginkgo biloba. The full-length cDNA encoding G. biloba GGPPS (designated as GbGGPPS) was 1657bp long and contained a 1176bp open reading frame encoding a 391 amino acid protein. Comparative analysis showed that GbGGPPS possessed a 79 amino acid transit peptide at its N-terminal, which directed GbGGPPS to target to the plastids. Bioinformatic analysis revealed that GbGGPPS was a member of polyprenyltransferases with two highly conserved aspartate-rich motifs like other plant GGPPSs. Phylogenetic tree analysis indicated that plant GGPPSs could be classified into two groups, angiosperm and gymnosperm GGPPSs, while GbGGPPS had closer relationship with gymnosperm plant GGPPSs.","lang":"eng"}],"volume":15,"quality_controlled":"1"},{"day":"01","publisher":"Kyoritsu Shuppan","type":"review","issue":"3 Suppl","status":"public","extern":1,"page":"287 - 294","intvolume":"        49","author":[{"first_name":"Akiko","full_name":"Momiyama, Akiko","last_name":"Momiyama"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto"}],"publication":"Tanpakushitsu kakusan koso Protein nucleic acid enzyme","year":"2004","date_updated":"2020-07-14T12:45:44Z","date_published":"2004-02-01T00:00:00Z","citation":{"ista":"Momiyama A, Shigemoto R. 2004. Function and distribution of glutamate receptors in the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme. 49(3 Suppl), 287–294.","chicago":"Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate Receptors in the Central Synapses.” <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>. Kyoritsu Shuppan, 2004.","apa":"Momiyama, A., &#38; Shigemoto, R. (2004). Function and distribution of glutamate receptors in the central synapses. <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>. Kyoritsu Shuppan.","ama":"Momiyama A, Shigemoto R. Function and distribution of glutamate receptors in the central synapses. <i>Tanpakushitsu kakusan koso Protein nucleic acid enzyme</i>. 2004;49(3 Suppl):287-294.","ieee":"A. Momiyama and R. Shigemoto, “Function and distribution of glutamate receptors in the central synapses,” <i>Tanpakushitsu kakusan koso Protein nucleic acid enzyme</i>, vol. 49, no. 3 Suppl. Kyoritsu Shuppan, pp. 287–294, 2004.","short":"A. Momiyama, R. Shigemoto, Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme 49 (2004) 287–294.","mla":"Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate Receptors in the Central Synapses.” <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>, vol. 49, no. 3 Suppl, Kyoritsu Shuppan, 2004, pp. 287–94."},"quality_controlled":0,"title":"Function and distribution of glutamate receptors in the central synapses","month":"02","volume":49,"_id":"2636","publist_id":"4261","date_created":"2018-12-11T11:58:48Z","publication_status":"published"},{"publisher":"Wiley-Blackwell","type":"journal_article","day":"01","issue":"8","status":"public","extern":1,"intvolume":"        19","page":"2169 - 2178","publication":"European Journal of Neuroscience","author":[{"full_name":"Kulik, Ákos","last_name":"Kulik","first_name":"Ákos"},{"first_name":"Kazuhiko","full_name":"Nakadate, Kazuhiko","last_name":"Nakadate"},{"first_name":"Akari","last_name":"Hagiwara","full_name":"Hagiwara, Akari"},{"last_name":"Fukazawa","full_name":"Fukazawa, Yugo","first_name":"Yugo"},{"last_name":"Luján","full_name":"Luján, Rafael","first_name":"Rafael"},{"full_name":"Saito, Hiromitsu","last_name":"Saito","first_name":"Hiromitsu"},{"full_name":"Suzuki, Noboru","last_name":"Suzuki","first_name":"Noboru"},{"first_name":"Akira","full_name":"Futatsugi, Akira","last_name":"Futatsugi"},{"full_name":"Mikoshiba, Katsuhiko","last_name":"Mikoshiba","first_name":"Katsuhiko"},{"first_name":"Michael","full_name":"Frotscher, Michael","last_name":"Frotscher"},{"orcid":"0000-0001-8761-9444","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto"}],"year":"2004","date_updated":"2021-01-12T06:58:44Z","date_published":"2004-04-01T00:00:00Z","citation":{"ieee":"Á. Kulik <i>et al.</i>, “Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum,” <i>European Journal of Neuroscience</i>, vol. 19, no. 8. Wiley-Blackwell, pp. 2169–2178, 2004.","mla":"Kulik, Ákos, et al. “Immunocytochemical Localization of the Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” <i>European Journal of Neuroscience</i>, vol. 19, no. 8, Wiley-Blackwell, 2004, pp. 2169–78, doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">10.1111/j.0953-816X.2004.03319.x</a>.","short":"Á. Kulik, K. Nakadate, A. Hagiwara, Y. Fukazawa, R. Luján, H. Saito, N. Suzuki, A. Futatsugi, K. Mikoshiba, M. Frotscher, R. Shigemoto, European Journal of Neuroscience 19 (2004) 2169–2178.","ista":"Kulik Á, Nakadate K, Hagiwara A, Fukazawa Y, Luján R, Saito H, Suzuki N, Futatsugi A, Mikoshiba K, Frotscher M, Shigemoto R. 2004. Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European Journal of Neuroscience. 19(8), 2169–2178.","chicago":"Kulik, Ákos, Kazuhiko Nakadate, Akari Hagiwara, Yugo Fukazawa, Rafael Luján, Hiromitsu Saito, Noboru Suzuki, et al. “Immunocytochemical Localization of the Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">https://doi.org/10.1111/j.0953-816X.2004.03319.x</a>.","apa":"Kulik, Á., Nakadate, K., Hagiwara, A., Fukazawa, Y., Luján, R., Saito, H., … Shigemoto, R. (2004). Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">https://doi.org/10.1111/j.0953-816X.2004.03319.x</a>","ama":"Kulik Á, Nakadate K, Hagiwara A, et al. Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. <i>European Journal of Neuroscience</i>. 2004;19(8):2169-2178. doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">10.1111/j.0953-816X.2004.03319.x</a>"},"abstract":[{"lang":"eng","text":"Among various types of low- and high-threshold calcium channels, the high voltage-activated P/Q-type channel is the most abundant in the cerebellum. These P/Q-type channels are involved in the regulation of neurotransmitter release and in the integration of dendritic inputs. We used an antibody specific for the α1A subunit of the P/Q-type channel in quantitative pre-embedding immunogold labelling combined with three-dimensional reconstruction to reveal the subcellular distribution of pre- and postsynaptic P/Q-type channels in the rat cerebellum. At the light microscopic level, immunoreactivity for the α1A protein was prevalent in the molecular layer, whereas immunostaining was moderate in the somata of Purkinje cells and weak in the granule cell layer. At the electron microscopic level, the most intense Immunoreactivity for the α1A subunit was found in the presynaptic active zone of parallel fibre varicosities. The dendritic spines of Purkinje cells were also strongly labelled with the highest density of immunoparticles detected within 180 nm from the edge of the asymmetrical parallel fibre-Purkinje cell synapses. By contrast, the immunolabelling was sparse in climbing fibre varicosities and axon terminals of GABAergic cells, and weak and diffuse in dendritic shafts of Purkinje cells. The association of the α1A subunit with the glutamatergic parallel fibre-Purkinje cell synapses suggests that presynaptic channels have a major role in the mediation of excitatory neurotransmission, whereas postsynaptic channels are likely to be involved in depolarization-induced generation of local calcium transients in Purkinje cells."}],"quality_controlled":0,"title":"Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum","month":"04","volume":19,"_id":"2638","doi":"10.1111/j.0953-816X.2004.03319.x","publist_id":"4259","date_created":"2018-12-11T11:58:48Z","publication_status":"published"},{"title":"GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat","quality_controlled":0,"month":"02","_id":"2639","volume":19,"citation":{"mla":"Somogyi, Jozsef, et al. “GABAergic Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the Rat.” <i>European Journal of Neuroscience</i>, vol. 19, no. 3, Wiley-Blackwell, 2004, pp. 552–69, doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">10.1111/j.0953-816X.2003.03091.x</a>.","short":"J. Somogyi, A. Baude, Y. Omori, H. Shimizu, S. El Mestikawy, M. Fukaya, R. Shigemoto, M. Watanabe, P. Somogyi, European Journal of Neuroscience 19 (2004) 552–569.","ieee":"J. Somogyi <i>et al.</i>, “GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat,” <i>European Journal of Neuroscience</i>, vol. 19, no. 3. Wiley-Blackwell, pp. 552–569, 2004.","ama":"Somogyi J, Baude A, Omori Y, et al. GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. <i>European Journal of Neuroscience</i>. 2004;19(3):552-569. doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">10.1111/j.0953-816X.2003.03091.x</a>","apa":"Somogyi, J., Baude, A., Omori, Y., Shimizu, H., El Mestikawy, S., Fukaya, M., … Somogyi, P. (2004). GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">https://doi.org/10.1111/j.0953-816X.2003.03091.x</a>","chicago":"Somogyi, Jozsef, Agnès Baude, Yuko Omori, Hidemi Shimizu, Salah El Mestikawy, Masahiro Fukaya, Ryuichi Shigemoto, Masahiko Watanabe, and Péter Somogyi. “GABAergic Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the Rat.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">https://doi.org/10.1111/j.0953-816X.2003.03091.x</a>.","ista":"Somogyi J, Baude A, Omori Y, Shimizu H, El Mestikawy S, Fukaya M, Shigemoto R, Watanabe M, Somogyi P. 2004. GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. European Journal of Neuroscience. 19(3), 552–569."},"abstract":[{"lang":"eng","text":"Vesicular glutamate transporter type 3 (VGLUT3) containing neuronal elements were characterized using antibodies to VGLUT3 and molecular cell markers. All VGLUT3-positive somata were immunoreactive for CCK, and very rarely, also for calbindin; none was positive for parvalbumin, calretinin, VIP or somatostatin. In the CA1 area, 26.8 ± 0.7% of CCK-positive interneuron somata were VGLUT3-positive, a nonoverlapping 22.8 ± 1.9% were calbindin-positive, 10.7 ± 2.5% VIP-positive and the rest were only CCK-positive. The patterns of coexpression were similar in the CA3 area, the dentate gyrus and the isocortex. Immunoreactivity for VGLUT3 was undetectable in pyramidal and dentate granule cells. Boutons colabelled for VGLUT3, CCK and GAD were most abundant in the cellular layers of the hippocampus and in layers II-III of the isocortex. Large VGLUT3-labelled boutons at the border of strata radiatum and lacunosum-moleculare in the CA1 area were negative for GAD, but were labelled for vesicular monoamine transporter type 2, plasmalemmal serotonin transporter or serotonin. No colocalization was found in terminals between VGLUT3 and parvalbumin, vesicular acetylcholine transporter and group III (mGluR7a,b; mGluR8a,b) metabotropic glutamate receptors. In stratum radiatum and the isocortex, VGLUT3-positive but GAD-negative boutons heavily innervated the soma and proximal dendrites of some VGLUT3- or calbindin-positive interneurons. The results suggest that boutons coexpressing VGLUT3, CCK and GAD originate from CCK-positive basket cells, which are VIP-immunonegative. Other VGLUT3-positive boutons immunopositive for serotonergic markers but negative for GAD probably originate from the median raphe nucleus and innervate select interneurons. The presumed amino acid substrate of VGLUT3 may act on presynaptic kainate or group II metabotropic glutamate receptors."}],"publication_status":"published","doi":"10.1111/j.0953-816X.2003.03091.x","publist_id":"4260","date_created":"2018-12-11T11:58:49Z","status":"public","day":"01","publisher":"Wiley-Blackwell","type":"journal_article","issue":"3","year":"2004","date_updated":"2021-01-12T06:58:44Z","date_published":"2004-02-01T00:00:00Z","extern":1,"intvolume":"        19","page":"552 - 569","publication":"European Journal of Neuroscience","author":[{"full_name":"Somogyi, Jozsef","last_name":"Somogyi","first_name":"Jozsef"},{"first_name":"Agnès","full_name":"Baude, Agnès","last_name":"Baude"},{"first_name":"Yuko","last_name":"Omori","full_name":"Omori, Yuko"},{"last_name":"Shimizu","full_name":"Shimizu, Hidemi","first_name":"Hidemi"},{"first_name":"Salah","full_name":"El-Mestikawy, Salah","last_name":"El Mestikawy"},{"full_name":"Fukaya, Masahiro","last_name":"Fukaya","first_name":"Masahiro"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto"},{"full_name":"Watanabe, Masahiko","last_name":"Watanabe","first_name":"Masahiko"},{"full_name":"Somogyi, Péter","last_name":"Somogyi","first_name":"Péter"}]},{"issue":"3","publisher":"Wiley-Blackwell","type":"journal_article","day":"05","status":"public","author":[{"full_name":"Notomi, Takuya","last_name":"Notomi","first_name":"Takuya"},{"last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444"}],"publication":"Journal of Comparative Neurology","intvolume":"       471","page":"241 - 276","extern":1,"date_published":"2004-04-05T00:00:00Z","date_updated":"2021-01-12T06:58:45Z","year":"2004","abstract":[{"text":"Hyperpolarization-activated cation currents (Ih) contribute to various physiological properties and functions in the brain, including neuronal pacemaker activity, setting of resting membrane potential, and dendritic integration of synaptic input. Four subunits of the Hyperpolarization-activated and Cyclic-Nucleotide-gated nonselective cation channels (HCN1-4), which generate Ih, have been cloned recently. To better understand the functional diversity of Ih in the brain, we examined precise immunohistochemical localization of four HCNs in the rat brain. Immunoreactivity for HCN1 showed predominantly cortical distribution, being intense in the neocortex, hippocampus, superior colliculus, and cerebellum, whereas those for HCN3 and HCN4 exhibited subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively. Immunoreactivity for HCN2 had a widespread distribution throughout the brain. Double immunofluorescence revealed colocalization of immunoreactivity for HCN1 and HCN2 in distal dendrites of pyramidal cells in the hippocampus and neocortex. At the electron microscopic level, immunogold particles for HCN1 and HCN2 had similar distribution patterns along plasma membrane of dendritic shafts in layer I of the neocortex and stratum lacunosum moleculare of the hippocampal CA1 area, suggesting that these subunits could form heteromeric channels. Our results further indicate that HCNs are localized not only in somato-dendritic compartments but also in axonal compartments of neurons. Immunoreactivity for HCNs often occurred in preterminal rather than terminal portions of axons and in specific populations of myelinated axons. We also found HCN2-immunopositive oligodendrocytes including perineuronal oligodendrocytes throughout the brain. These results support previous electrophysiological findings and further suggest unexpected roles of Ih channels in the brain.","lang":"eng"}],"citation":{"mla":"Notomi, Takuya, and Ryuichi Shigemoto. “Immunohistochemical Localization of Ih Channel Subunits, HCN1-4, in the Rat Brain.” <i>Journal of Comparative Neurology</i>, vol. 471, no. 3, Wiley-Blackwell, 2004, pp. 241–76, doi:<a href=\"https://doi.org/10.1002/cne.11039\">10.1002/cne.11039</a>.","short":"T. Notomi, R. Shigemoto, Journal of Comparative Neurology 471 (2004) 241–276.","ieee":"T. Notomi and R. Shigemoto, “Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain,” <i>Journal of Comparative Neurology</i>, vol. 471, no. 3. Wiley-Blackwell, pp. 241–276, 2004.","apa":"Notomi, T., &#38; Shigemoto, R. (2004). Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. <i>Journal of Comparative Neurology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cne.11039\">https://doi.org/10.1002/cne.11039</a>","ama":"Notomi T, Shigemoto R. Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. <i>Journal of Comparative Neurology</i>. 2004;471(3):241-276. doi:<a href=\"https://doi.org/10.1002/cne.11039\">10.1002/cne.11039</a>","ista":"Notomi T, Shigemoto R. 2004. Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. Journal of Comparative Neurology. 471(3), 241–276.","chicago":"Notomi, Takuya, and Ryuichi Shigemoto. “Immunohistochemical Localization of Ih Channel Subunits, HCN1-4, in the Rat Brain.” <i>Journal of Comparative Neurology</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1002/cne.11039\">https://doi.org/10.1002/cne.11039</a>."},"volume":471,"_id":"2640","month":"04","title":"Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain","quality_controlled":0,"date_created":"2018-12-11T11:58:49Z","publist_id":"4258","doi":"10.1002/cne.11039","publication_status":"published"},{"publication":"Journal of Neuroscience","author":[{"full_name":"Kang, Youngnam","last_name":"Kang","first_name":"Youngnam"},{"first_name":"Takuya","full_name":"Notomi, Takuya","last_name":"Notomi"},{"first_name":"Mitsuru","last_name":"Saito","full_name":"Saito, Mitsuru"},{"last_name":"Zhang","full_name":"Zhang, Wei","first_name":"Wei"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto"}],"intvolume":"        24","page":"3694 - 3702","extern":1,"date_published":"2004-04-07T00:00:00Z","date_updated":"2021-01-12T06:58:45Z","year":"2004","issue":"14","type":"journal_article","publisher":"Society for Neuroscience","day":"07","status":"public","date_created":"2018-12-11T11:58:49Z","publist_id":"4257","doi":"10.1523/JNEUROSCI.5641-03.2004","publication_status":"published","abstract":[{"text":"The Na+-K+ pump current (Ip) and the h-current (Ih) flowing through hyperpolarization-activated channels (h-channels) participate in generating the resting potential. These two currents are thought to be produced independently. We show here bidirectional interactions between Na+-K+ pumps and h-channels in mesencephalic trigeminal neurons. Activation of Ih leads to the generation of two types of ouabain-sensitive Ip with temporal profiles similar to those of instantaneous and slow components of I h, presumably reflecting Na+ transients in a restricted cellular space. Moreover, the Ip activated by instantaneous I h can facilitate the subsequent activation of slow Ih. Such counteractive and cooperative interactions were also disclosed by replacing extracellular Na+ with Li+, which is permeant through h-channels but does not stimulate the Na+-K+ pump as strongly as Na+ ions. These observations indicate that the interactions are bidirectional and mediated by Na+ ions. Also after substitution of extracellular Na+ with Li+, the tail Ih was reduced markedly despite an enhancement of Ih itself, attributable to a negative shift of the reversal potential for I h presumably caused by intracellular accumulation of Li+ ions. This suggests the presence of a microdomain where the interactions can take place. Thus, the bidirectional interactions between Na+-K + pumps and h-channels are likely to be mediated by Na+ microdomain. Consistent with these findings, hyperpolarization-activated and cyclic nucleotide-modulated subunits (HCN1/2) and the Na+-K + pump α3 isoform were colocalized in plasma membrane of mesencephalic trigeminal neurons having numerous spines.","lang":"eng"}],"citation":{"ama":"Kang Y, Notomi T, Saito M, Zhang W, Shigemoto R. Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons. <i>Journal of Neuroscience</i>. 2004;24(14):3694-3702. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.5641-03.2004\">10.1523/JNEUROSCI.5641-03.2004</a>","apa":"Kang, Y., Notomi, T., Saito, M., Zhang, W., &#38; Shigemoto, R. (2004). Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.5641-03.2004\">https://doi.org/10.1523/JNEUROSCI.5641-03.2004</a>","chicago":"Kang, Youngnam, Takuya Notomi, Mitsuru Saito, Wei Zhang, and Ryuichi Shigemoto. “Bidirectional Interactions between H-Channels and Na+-K + Pumps in Mesencephalic Trigeminal Neurons.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2004. <a href=\"https://doi.org/10.1523/JNEUROSCI.5641-03.2004\">https://doi.org/10.1523/JNEUROSCI.5641-03.2004</a>.","ista":"Kang Y, Notomi T, Saito M, Zhang W, Shigemoto R. 2004. Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons. Journal of Neuroscience. 24(14), 3694–3702.","short":"Y. Kang, T. Notomi, M. Saito, W. Zhang, R. Shigemoto, Journal of Neuroscience 24 (2004) 3694–3702.","mla":"Kang, Youngnam, et al. “Bidirectional Interactions between H-Channels and Na+-K + Pumps in Mesencephalic Trigeminal Neurons.” <i>Journal of Neuroscience</i>, vol. 24, no. 14, Society for Neuroscience, 2004, pp. 3694–702, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.5641-03.2004\">10.1523/JNEUROSCI.5641-03.2004</a>.","ieee":"Y. Kang, T. Notomi, M. Saito, W. Zhang, and R. Shigemoto, “Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons,” <i>Journal of Neuroscience</i>, vol. 24, no. 14. Society for Neuroscience, pp. 3694–3702, 2004."},"volume":24,"_id":"2641","month":"04","quality_controlled":0,"title":"Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons"},{"status":"public","issue":"2","type":"journal_article","publisher":"Wiley-Blackwell","day":"01","date_published":"2004-01-01T00:00:00Z","date_updated":"2021-01-12T06:58:46Z","year":"2004","publication":"Hippocampus","author":[{"first_name":"Francesco","full_name":"Ferraguti, Francesco","last_name":"Ferraguti"},{"full_name":"Cobden, Philip M","last_name":"Cobden","first_name":"Philip"},{"first_name":"Marie","last_name":"Pollard","full_name":"Pollard, Marie"},{"first_name":"David","last_name":"Cope","full_name":"Cope, David W"},{"orcid":"0000-0001-8761-9444","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto"},{"first_name":"Masahiko","full_name":"Watanabe, Masahiko","last_name":"Watanabe"},{"first_name":"Péter","last_name":"Somogyi","full_name":"Somogyi, Péter"}],"intvolume":"        14","page":"193 - 215","extern":1,"_id":"2642","volume":14,"month":"01","quality_controlled":0,"title":"Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus","abstract":[{"lang":"eng","text":"In the hippocampal CA1 region, metabotropic glutamate subtype 1 (mGluR1) receptors have been implicated in a variety of physiological responses to glutamate, which include modulation of synaptic transmission and plasticity, as well as neuronal excitability and synchronization. The mGluR1α isoform is characteristically expressed only by nonprincipal cells, and it is particularly enriched in somatostatin (SS -containing interneurons in stratum oriens-alveus. Anatomical and physiological data have indicated the presence of mGluR1α in several distinct classes of interneurons with their somata located also in strata pyramidale, radiatum, and lacunosum moleculare. Each different interneuron subtype, as defined by functionally relevant criteria, including input/output characteristics and expression of selective molecular markers, subserves distinct functions in local hippocampal circuits. We have investigated which of the different CA1 interneuron classes express mGluR1α by immunofluorescent labeling, combining antibodies to mGluR1α, calcium-binding proteins, and neuropeptides, and by intracellular labeling in vitro. Several types of interneuron that are immunopositive for mGluR1α each targeted different domains of pyramidal cells and included (1) O-LM interneurons, found to coexpress both SS and parvalbumin (PV); (2) interneurons with target selectivity for other interneurons, expressing vasoactive intestinal polypeptide (VIP) and/or the calcium-binding protein calretinin; (3) procholecystokinin-immunopositive interneurons probably non-basket and dendrite-targeting; and (4) an as-yet unidentified SS-immunoreactive but PV-immunonegative interneuron class, possibly corresponding to oriensbistratified cells. Estimation of the relative proportion of mGluR1α-positive interneurons showed 43%, 46%, and 30% co-labeling with SS, VIP, or PV, respectively. The identification of the specific subclasses of CA1 interneurons expressing mGluR1α provides the network basis for assessing the contribution of this receptor to the excitability of the hippocampus."}],"citation":{"chicago":"Ferraguti, Francesco, Philip Cobden, Marie Pollard, David Cope, Ryuichi Shigemoto, Masahiko Watanabe, and Péter Somogyi. “Immunolocalization of Metabotropic Glutamate Receptor 1α (MGluR1α) in Distinct Classes of Interneuron in the CA1 Region of the Rat Hippocampus.” <i>Hippocampus</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1002/hipo.10163\">https://doi.org/10.1002/hipo.10163</a>.","ista":"Ferraguti F, Cobden P, Pollard M, Cope D, Shigemoto R, Watanabe M, Somogyi P. 2004. Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus. Hippocampus. 14(2), 193–215.","ama":"Ferraguti F, Cobden P, Pollard M, et al. Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus. <i>Hippocampus</i>. 2004;14(2):193-215. doi:<a href=\"https://doi.org/10.1002/hipo.10163\">10.1002/hipo.10163</a>","apa":"Ferraguti, F., Cobden, P., Pollard, M., Cope, D., Shigemoto, R., Watanabe, M., &#38; Somogyi, P. (2004). Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus. <i>Hippocampus</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/hipo.10163\">https://doi.org/10.1002/hipo.10163</a>","ieee":"F. Ferraguti <i>et al.</i>, “Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus,” <i>Hippocampus</i>, vol. 14, no. 2. Wiley-Blackwell, pp. 193–215, 2004.","mla":"Ferraguti, Francesco, et al. “Immunolocalization of Metabotropic Glutamate Receptor 1α (MGluR1α) in Distinct Classes of Interneuron in the CA1 Region of the Rat Hippocampus.” <i>Hippocampus</i>, vol. 14, no. 2, Wiley-Blackwell, 2004, pp. 193–215, doi:<a href=\"https://doi.org/10.1002/hipo.10163\">10.1002/hipo.10163</a>.","short":"F. Ferraguti, P. Cobden, M. Pollard, D. Cope, R. Shigemoto, M. Watanabe, P. Somogyi, Hippocampus 14 (2004) 193–215."},"publication_status":"published","date_created":"2018-12-11T11:58:50Z","publist_id":"4256","doi":"10.1002/hipo.10163"},{"citation":{"mla":"Luján, Rafael, et al. “Localization of the GABAB Receptor 1a/b Subunit Relative to Glutamatergic Synapses in the Dorsal Cochlear Nucleus of the Rat.” <i>Journal of Comparative Neurology</i>, vol. 475, no. 1, Wiley-Blackwell, 2004, pp. 36–46, doi:<a href=\"https://doi.org/10.1002/cne.20160\">10.1002/cne.20160</a>.","short":"R. Luján, R. Shigemoto, Á. Kulik, J. Juíz, Journal of Comparative Neurology 475 (2004) 36–46.","ieee":"R. Luján, R. Shigemoto, Á. Kulik, and J. Juíz, “Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the rat,” <i>Journal of Comparative Neurology</i>, vol. 475, no. 1. Wiley-Blackwell, pp. 36–46, 2004.","apa":"Luján, R., Shigemoto, R., Kulik, Á., &#38; Juíz, J. (2004). Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the rat. <i>Journal of Comparative Neurology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cne.20160\">https://doi.org/10.1002/cne.20160</a>","ama":"Luján R, Shigemoto R, Kulik Á, Juíz J. Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the rat. <i>Journal of Comparative Neurology</i>. 2004;475(1):36-46. doi:<a href=\"https://doi.org/10.1002/cne.20160\">10.1002/cne.20160</a>","ista":"Luján R, Shigemoto R, Kulik Á, Juíz J. 2004. Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the rat. Journal of Comparative Neurology. 475(1), 36–46.","chicago":"Luján, Rafael, Ryuichi Shigemoto, Ákos Kulik, and José Juíz. “Localization of the GABAB Receptor 1a/b Subunit Relative to Glutamatergic Synapses in the Dorsal Cochlear Nucleus of the Rat.” <i>Journal of Comparative Neurology</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1002/cne.20160\">https://doi.org/10.1002/cne.20160</a>."},"abstract":[{"lang":"eng","text":"Metabotropic γ-aminobutyric acid receptors (GABAB) are involved in pre- and postsynaptic inhibitory effects upon auditory neurons and have been implicated in different aspects of acoustic information processing. To understand better the mechanisms by which GABAB receptors mediate their inhibitory effects, we used pre-embedding immunocytochemical techniques combined with quantification of immunogold particles to reveal the precise subcellular distribution of the GABAB1 subunit in the rat dorsal cochlear nucleus. At the light microscopic level, GABAB1 was detected in all divisions of the cochlear complex. The most intense immunoreactivity for GABAB1 was found in the dorsal cochlear nucleus, whereas immunoreactivity in the anteroventral and posteroventral cochlear nuclei was very low. In the dorsal cochlear nucleus, a punctate labeling was observed in the superficial (molecular and fusiform cell) layers. At the electron microscopic level, GABAB1 was found at both post- and presynaptic locations. Postsynaptically, GABAB1 was localized mainly in the dendritic spines of presumed fusiform cells. Quantitative immunogold immunocytochemistry revealed that the highest concentration of GABA B1 in the plasma membrane was in dendritic spines, followed by dendritic shafts and somata. Thus, the most intense immunoreactivity for GABAB1 was observed in dendritic spines with a high density of immunogold particles at extrasynaptic sites, peaking around 300 nm from glutamatergic synapses. This is in contrast to GABAergic synapses, in which GABAB1 was only occasionally found. Presynaptically, receptor immunoreactivity was detected primarily in axospinous endings, probably from granule cells, in both the active zone and extrasynaptic sites. The localization of GABAB1 relative to synaptic sites in the DCN suggests a role for the receptor in the regulation of dendritic excitability and excitatory inputs."}],"month":"07","title":"Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the rat","quality_controlled":0,"_id":"2643","volume":475,"doi":"10.1002/cne.20160","publist_id":"4254","date_created":"2018-12-11T11:58:50Z","publication_status":"published","issue":"1","day":"12","publisher":"Wiley-Blackwell","type":"journal_article","status":"public","page":"36 - 46","intvolume":"       475","extern":1,"author":[{"first_name":"Rafael","full_name":"Luján, Rafael","last_name":"Luján"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto","orcid":"0000-0001-8761-9444"},{"first_name":"Ákos","last_name":"Kulik","full_name":"Kulik, Ákos"},{"first_name":"José","full_name":"Juíz, José M","last_name":"Juíz"}],"publication":"Journal of Comparative Neurology","date_updated":"2021-01-12T06:58:46Z","year":"2004","date_published":"2004-07-12T00:00:00Z"},{"citation":{"apa":"Kogo, N., Dalezios, Y., Capogna, M., Ferraguti, F., Shigemoto, R., &#38; Somogyi, P. (2004). Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03394.x\">https://doi.org/10.1111/j.0953-816X.2004.03394.x</a>","ama":"Kogo N, Dalezios Y, Capogna M, Ferraguti F, Shigemoto R, Somogyi P. Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat. <i>European Journal of Neuroscience</i>. 2004;19(10):2727-2740. doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03394.x\">10.1111/j.0953-816X.2004.03394.x</a>","ista":"Kogo N, Dalezios Y, Capogna M, Ferraguti F, Shigemoto R, Somogyi P. 2004. Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat. European Journal of Neuroscience. 19(10), 2727–2740.","chicago":"Kogo, Naoki, Yannis Dalezios, Marco Capogna, Francesco Ferraguti, Ryuichi Shigemoto, and Péter Somogyi. “Depression of GABAergic Input to Identified Hippocampal Neurons by Group III Metabotropic Glutamate Receptors in the Rat.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03394.x\">https://doi.org/10.1111/j.0953-816X.2004.03394.x</a>.","mla":"Kogo, Naoki, et al. “Depression of GABAergic Input to Identified Hippocampal Neurons by Group III Metabotropic Glutamate Receptors in the Rat.” <i>European Journal of Neuroscience</i>, vol. 19, no. 10, Wiley-Blackwell, 2004, pp. 2727–40, doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03394.x\">10.1111/j.0953-816X.2004.03394.x</a>.","short":"N. Kogo, Y. Dalezios, M. Capogna, F. Ferraguti, R. Shigemoto, P. Somogyi, European Journal of Neuroscience 19 (2004) 2727–2740.","ieee":"N. Kogo, Y. Dalezios, M. Capogna, F. Ferraguti, R. Shigemoto, and P. Somogyi, “Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat,” <i>European Journal of Neuroscience</i>, vol. 19, no. 10. Wiley-Blackwell, pp. 2727–2740, 2004."},"abstract":[{"text":"The release of GABA in synapses is modulated by presynaptic metabotropic glutamate receptors (mGluRs). We tested whether GABA release to identified hippocampal neurons is influenced by group III mGluR activation using the agonist L-(+)-2-amino-4-phosphonobutyric acid (L-AP4) on inhibitory postsynaptic currents (IPSCs) evoked in CA1 interneurons and pyramidal cells. In interneurons, characterized with biocytin and immunolabelling for somatostatin, evoked IPSCs were depressed by 50 μM L-AP4 (activating mGluR4 and 8) to 68±6% of control, but they were rarely depressed in pyramidal cells (96±4% of control). At 300-500 μM concentration (activating mGluR4, 7 and 8), L-AP4 depressed IPSCs in both interneurons (to 70±6%) and pyramidal cells (to 67±4%). The change in trial-to-trial variability and in paired-pulse depression indicated a presynaptic action. In interneurons, the degree of IPSC depression was variable (to 9-87%), and a third of IPSCs were not affected by L-AP4. The L-AP4-evoked IPSC depression was blocked by LY341495. The depression of IPSCs was similar in O-LM cells and other interneurons. The lack of cell-type selectivity and the similar efficacy of different concentrations of L-AP4 suggest that several group III mGluRs are involved in the depression of IPSCs. Electron microscopic immunocytochemistry confirmed that mGluR4, mGluR7a and mGluR8a occur in the presynaptic active zone of GABAergic terminals on interneurons, but not on those innervating pyramidal cells. The high variability of L-AP4-evoked IPSC suppression is in line with the selective expression of presynaptic mGluRs by several distinct types of GABAergic neuron innervating each interneuron type.","lang":"eng"}],"title":"Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat","quality_controlled":0,"month":"05","volume":19,"_id":"2644","publist_id":"4255","doi":"10.1111/j.0953-816X.2004.03394.x","date_created":"2018-12-11T11:58:50Z","publication_status":"published","type":"journal_article","day":"01","publisher":"Wiley-Blackwell","issue":"10","status":"public","extern":1,"page":"2727 - 2740","intvolume":"        19","publication":"European Journal of Neuroscience","author":[{"full_name":"Kogo, Naoki","last_name":"Kogo","first_name":"Naoki"},{"first_name":"Yannis","full_name":"Dalezios, Yannis","last_name":"Dalezios"},{"first_name":"Marco","last_name":"Capogna","full_name":"Capogna,Marco"},{"first_name":"Francesco","full_name":"Ferraguti, Francesco","last_name":"Ferraguti"},{"orcid":"0000-0001-8761-9444","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi"},{"first_name":"Péter","full_name":"Somogyi, Péter","last_name":"Somogyi"}],"year":"2004","date_updated":"2021-01-12T06:58:46Z","date_published":"2004-05-01T00:00:00Z"},{"day":"03","publisher":"Society for Neuroscience","type":"journal_article","issue":"44","status":"public","extern":1,"intvolume":"        24","page":"9921 - 9932","author":[{"first_name":"Savio","last_name":"Chan","full_name":"Chan, Savio"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto"},{"full_name":"Mercer, Jeff N","last_name":"Mercer","first_name":"Jeff"},{"first_name":"James","last_name":"Surmeier","full_name":"Surmeier, James D"}],"publication":"Journal of Neuroscience","year":"2004","date_updated":"2021-01-12T06:58:47Z","date_published":"2004-11-03T00:00:00Z","citation":{"ieee":"S. Chan, R. Shigemoto, J. Mercer, and J. Surmeier, “HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons,” <i>Journal of Neuroscience</i>, vol. 24, no. 44. Society for Neuroscience, pp. 9921–9932, 2004.","mla":"Chan, Savio, et al. “HCN2 and HCN1 Channels Govern the Regularity of Autonomous Pacemaking and Synaptic Resetting in Globus Pallidus Neurons.” <i>Journal of Neuroscience</i>, vol. 24, no. 44, Society for Neuroscience, 2004, pp. 9921–32, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.2162-04.2004\">10.1523/JNEUROSCI.2162-04.2004</a>.","short":"S. Chan, R. Shigemoto, J. Mercer, J. Surmeier, Journal of Neuroscience 24 (2004) 9921–9932.","ista":"Chan S, Shigemoto R, Mercer J, Surmeier J. 2004. HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. Journal of Neuroscience. 24(44), 9921–9932.","chicago":"Chan, Savio, Ryuichi Shigemoto, Jeff Mercer, and James Surmeier. “HCN2 and HCN1 Channels Govern the Regularity of Autonomous Pacemaking and Synaptic Resetting in Globus Pallidus Neurons.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2004. <a href=\"https://doi.org/10.1523/JNEUROSCI.2162-04.2004\">https://doi.org/10.1523/JNEUROSCI.2162-04.2004</a>.","apa":"Chan, S., Shigemoto, R., Mercer, J., &#38; Surmeier, J. (2004). HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.2162-04.2004\">https://doi.org/10.1523/JNEUROSCI.2162-04.2004</a>","ama":"Chan S, Shigemoto R, Mercer J, Surmeier J. HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. <i>Journal of Neuroscience</i>. 2004;24(44):9921-9932. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.2162-04.2004\">10.1523/JNEUROSCI.2162-04.2004</a>"},"abstract":[{"lang":"eng","text":"The globus pallidus (GP) is a critical component of the basal ganglia circuitry controlling motor behavior. Dysregulation of GP activity has been implicated in a number of psychomotor disorders, including Parkinson's disease (PD), in which a cardinal feature of the pathophysiology is an alteration in the pattern and synchrony of discharge in GP neurons. Yet the determinants of this activity in GP neurons are poorly understood. To help fill this gap, electrophysiological, molecular, and computational approaches were used to identify and characterize GABAergic GP neurons in tissue slices from rodents. In vitro, GABAergic GP neurons generate a regular, autonomous, single-spike pacemaker activity. Hyperpolarization-activated, cyclic nucleotide-gated cation (HCN) channels make an important contribution to this process: their blockade with ZD7288 significantly slowed discharge rate and decreased its regularity. HCN currents evoked by somatic voltage clamp had fast and slow components. Single-cell RT-PCR and immunohistochemical approaches revealed robust expression of HCN2 subunits as well as significant levels of HCN1 subunits in GABAergic GP neurons. Transient activation of striatal GABAergic input to GP neurons led to a resetting of rhythmic discharge that was dependent on HCN currents. Simulations suggested that the ability of transient striatal GABAergic input to reset pacemaking was dependent on dendritic HCN2/HCN1 channels. Together, these studies show that HCN channels in GABAergic GP neurons are key determinants of the regularity and rate of pacemaking as well as striatal resetting of this activity, implicating HCN channels in the emergence of synchrony in PD."}],"title":"HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons","quality_controlled":0,"month":"11","_id":"2645","volume":24,"doi":"10.1523/JNEUROSCI.2162-04.2004","publist_id":"4252","date_created":"2018-12-11T11:58:51Z","publication_status":"published"},{"publication_status":"published","date_created":"2018-12-11T11:58:51Z","doi":"10.1002/hipo.10221","publist_id":"4251","volume":14,"_id":"2646","title":" Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus during prenatal and postnatal development","quality_controlled":0,"month":"01","abstract":[{"text":"Metabotropic γ-aminobutyric acid receptors (GABAB) play modulatory roles in central synaptic transmission and are involved in controlling neuronal migration during development. We used immunohistochemical methods to elucidate the expression pattern as well as the cellular and the precise subcellular localization of the GABAB1a/b and GABAB2 subunits in the rat hippocampus during prenatal and postnatal development. At the light microscopic level, both GABABB1a/b and GABAB2 were expressed in the hippocampal primordium from embryonic day E14. During postnatal development, immunoreactivity for GABAB1a/b and GABAB2 was distributed mainly in pyramidal cells, with discrete GABABB1a/b-immunopositive cell bodies of interneurons present throughout the hippocampus. Using double immunofluorescence, we demonstrated that during the second week of postnatal development, GABAB1a/b but not GABAB2 was expressed in glial cells throughout the hippocampal formation. At the electron microscopic level, GABAB1a/b and GABAB2 showed a similar distribution pattern during postnatal development. Thus, at all ages the two receptor subunits were located postsynaptically in dendritic spines and shafts at extrasynaptic and perisynaptic sites in both pyramidal and nonpyramidal cells. We further demonstrated that the two subunits were localized presynaptically along the extrasynaptic plasma membrane of axon terminals and along the presynaptic active zone in both asymmetrical and, to a lesser extent, symmetrical synapses. These results suggest that GABAB receptors are widely expressed in the hippocampus throughout development and that GABABB1a/b and GABAB2 form both pre- and postsynaptic receptors.","lang":"eng"}],"citation":{"mla":"López Bendito, Guillermina, et al. “ Distribution of Metabotropic GABA Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus during Prenatal and Postnatal Development.” <i>Hippocampus</i>, vol. 14, no. 7, Wiley-Blackwell, 2004, pp. 836–48, doi:<a href=\"https://doi.org/10.1002/hipo.10221\">10.1002/hipo.10221</a>.","short":"G. López Bendito, R. Shigemoto, Á. Kulik, I. Vida, A. Fairén, R. Luján, Hippocampus 14 (2004) 836–848.","ieee":"G. López Bendito, R. Shigemoto, Á. Kulik, I. Vida, A. Fairén, and R. Luján, “ Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus during prenatal and postnatal development,” <i>Hippocampus</i>, vol. 14, no. 7. Wiley-Blackwell, pp. 836–848, 2004.","apa":"López Bendito, G., Shigemoto, R., Kulik, Á., Vida, I., Fairén, A., &#38; Luján, R. (2004).  Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus during prenatal and postnatal development. <i>Hippocampus</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/hipo.10221\">https://doi.org/10.1002/hipo.10221</a>","ama":"López Bendito G, Shigemoto R, Kulik Á, Vida I, Fairén A, Luján R.  Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus during prenatal and postnatal development. <i>Hippocampus</i>. 2004;14(7):836-848. doi:<a href=\"https://doi.org/10.1002/hipo.10221\">10.1002/hipo.10221</a>","ista":"López Bendito G, Shigemoto R, Kulik Á, Vida I, Fairén A, Luján R. 2004.  Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus during prenatal and postnatal development. Hippocampus. 14(7), 836–848.","chicago":"López Bendito, Guillermina, Ryuichi Shigemoto, Ákos Kulik, Imre Vida, Alfonso Fairén, and Rafael Luján. “ Distribution of Metabotropic GABA Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus during Prenatal and Postnatal Development.” <i>Hippocampus</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1002/hipo.10221\">https://doi.org/10.1002/hipo.10221</a>."},"date_published":"2004-01-01T00:00:00Z","year":"2004","date_updated":"2021-01-12T06:58:47Z","author":[{"first_name":"Guillermina","last_name":"López Bendito","full_name":"López-Bendito, Guillermina"},{"orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto"},{"first_name":"Ákos","full_name":"Kulik, Ákos","last_name":"Kulik"},{"full_name":"Vida, Imre","last_name":"Vida","first_name":"Imre"},{"first_name":"Alfonso","full_name":"Fairén, Alfonso","last_name":"Fairén"},{"full_name":"Luján, Rafael","last_name":"Luján","first_name":"Rafael"}],"publication":"Hippocampus","extern":1,"page":"836 - 848","intvolume":"        14","status":"public","day":"01","publisher":"Wiley-Blackwell","type":"journal_article","issue":"7"},{"intvolume":"       116","page":"475 - 506","extern":1,"publication":"Journal of Statistical Physics","author":[{"orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","full_name":"László Erdös"},{"first_name":"Jan","full_name":"Solovej, Jan P","last_name":"Solovej"}],"date_updated":"2021-01-12T06:59:10Z","year":"2004","date_published":"2004-08-01T00:00:00Z","issue":"1-4","type":"journal_article","day":"01","publisher":"Springer","status":"public","doi":"10.1023/B:JOSS.0000037216.45270.1d","publist_id":"4190","date_created":"2018-12-11T11:59:10Z","publication_status":"published","citation":{"ama":"Erdös L, Solovej J. Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength. <i>Journal of Statistical Physics</i>. 2004;116(1-4):475-506. doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000037216.45270.1d\">10.1023/B:JOSS.0000037216.45270.1d</a>","apa":"Erdös, L., &#38; Solovej, J. (2004). Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength. <i>Journal of Statistical Physics</i>. Springer. <a href=\"https://doi.org/10.1023/B:JOSS.0000037216.45270.1d\">https://doi.org/10.1023/B:JOSS.0000037216.45270.1d</a>","chicago":"Erdös, László, and Jan Solovej. “Magnetic Lieb-Thirring Inequalities with Optimal Dependence on the Field Strength.” <i>Journal of Statistical Physics</i>. Springer, 2004. <a href=\"https://doi.org/10.1023/B:JOSS.0000037216.45270.1d\">https://doi.org/10.1023/B:JOSS.0000037216.45270.1d</a>.","ista":"Erdös L, Solovej J. 2004. Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength. Journal of Statistical Physics. 116(1–4), 475–506.","short":"L. Erdös, J. Solovej, Journal of Statistical Physics 116 (2004) 475–506.","mla":"Erdös, László, and Jan Solovej. “Magnetic Lieb-Thirring Inequalities with Optimal Dependence on the Field Strength.” <i>Journal of Statistical Physics</i>, vol. 116, no. 1–4, Springer, 2004, pp. 475–506, doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000037216.45270.1d\">10.1023/B:JOSS.0000037216.45270.1d</a>.","ieee":"L. Erdös and J. Solovej, “Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength,” <i>Journal of Statistical Physics</i>, vol. 116, no. 1–4. Springer, pp. 475–506, 2004."},"abstract":[{"lang":"eng","text":"The Pauli operator describes the energy of a nonrelativistic quantum particle with spin in a magnetic field and an external potential. Bounds on the sum of the negative eigenvalues are called magnetic Lieb-Thirring (MLT) inequalities. The purpose of this paper is twofold. First, we prove a new MLT inequality in a simple way. Second, we give a short summary of our recent proof of a more refined MLT inequality(8) and we explain the differences between the two results and methods. The main feature of both estimates, compared to earlier results, is that in the large field regime they grow with the optimal (first) power of the strength of the magnetic field. As a byproduct of the method, we also obtain optimal upper bounds on the pointwise density of zero energy eigenfunctions of the Dirac operator."}],"month":"08","title":"Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength","quality_controlled":0,"volume":116,"_id":"2706"},{"abstract":[{"lang":"eng","text":"We give a nonrigorous derivation of the nonlinear Boltzmann equation from the Schrödinger evolution of interacting fermions. The argument is based mainly on the assumption that a quasifree initial state satisfies a property called restricted quasifreeness in the weak coupling limit at any later time. By definition, a state is called restricted quasifree if the four-point and the eight-point functions of the state factorize in the same manner as in a quasifree state."}],"citation":{"mla":"Erdös, László, et al. “On the Quantum Boltzmann Equation.” <i>Journal of Statistical Physics</i>, vol. 116, no. 1–4, Springer, 2004, pp. 367–80, doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000037224.56191.ed\">10.1023/B:JOSS.0000037224.56191.ed</a>.","short":"L. Erdös, M. Salmhofer, H. Yau, Journal of Statistical Physics 116 (2004) 367–380.","ieee":"L. Erdös, M. Salmhofer, and H. Yau, “On the quantum Boltzmann equation,” <i>Journal of Statistical Physics</i>, vol. 116, no. 1–4. Springer, pp. 367–380, 2004.","apa":"Erdös, L., Salmhofer, M., &#38; Yau, H. (2004). On the quantum Boltzmann equation. <i>Journal of Statistical Physics</i>. Springer. <a href=\"https://doi.org/10.1023/B:JOSS.0000037224.56191.ed\">https://doi.org/10.1023/B:JOSS.0000037224.56191.ed</a>","ama":"Erdös L, Salmhofer M, Yau H. On the quantum Boltzmann equation. <i>Journal of Statistical Physics</i>. 2004;116(1-4):367-380. doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000037224.56191.ed\">10.1023/B:JOSS.0000037224.56191.ed</a>","ista":"Erdös L, Salmhofer M, Yau H. 2004. On the quantum Boltzmann equation. Journal of Statistical Physics. 116(1–4), 367–380.","chicago":"Erdös, László, Manfred Salmhofer, and Horng Yau. “On the Quantum Boltzmann Equation.” <i>Journal of Statistical Physics</i>. Springer, 2004. <a href=\"https://doi.org/10.1023/B:JOSS.0000037224.56191.ed\">https://doi.org/10.1023/B:JOSS.0000037224.56191.ed</a>."},"volume":116,"_id":"2707","month":"08","quality_controlled":0,"title":"On the quantum Boltzmann equation","date_created":"2018-12-11T11:59:11Z","doi":"10.1023/B:JOSS.0000037224.56191.ed","publist_id":"4189","publication_status":"published","issue":"1-4","day":"01","type":"journal_article","publisher":"Springer","status":"public","author":[{"orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","full_name":"László Erdös","last_name":"Erdös"},{"full_name":"Salmhofer, Manfred","last_name":"Salmhofer","first_name":"Manfred"},{"first_name":"Horng","full_name":"Yau, Horng-Tzer","last_name":"Yau"}],"publication":"Journal of Statistical Physics","page":"367 - 380","intvolume":"       116","extern":1,"date_published":"2004-08-01T00:00:00Z","date_updated":"2021-01-12T06:59:11Z","year":"2004"},{"abstract":[{"text":"The Pauli operator describes the energy of a nonrelativistic quantum particle with spin 1/2 in a magnetic field and an external potential. A new Lieb-Thirring type inequality on the sum of the negative eigenvalues is presented. The main feature compared to earlier results is that in the large field regime the present estimate grows with the optimal (first) power of the strength of the magnetic field. As a byproduct of the method, we also obtain an optimal upper bound on the pointwise density of zero energy eigenfunctions of the Dirac operator. The main technical tools are: (i) a new localization scheme for the square of the resolvent of a general class of second order elliptic operators; (ii) a geometric construction of a Dirac operator with a constant magnetic field that approximates the original Dirac operator in a tubular neighborhood of a fixed field line. The errors may depend on the regularity of the magnetic field but they are uniform in the field strength.","lang":"eng"}],"citation":{"chicago":"Erdös, László, and Jan Solovej. “Uniform Lieb-Thirring Inequality for the Three-Dimensional Pauli Operator with a Strong Non-Homogeneous Magnetic Field.” <i>Annales Henri Poincare</i>. Birkhäuser, 2004. <a href=\"https://doi.org/10.1007/s00023-004-0180-x\">https://doi.org/10.1007/s00023-004-0180-x</a>.","ista":"Erdös L, Solovej J. 2004. Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with a strong non-homogeneous magnetic field. Annales Henri Poincare. 5(4), 671–741.","ama":"Erdös L, Solovej J. Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with a strong non-homogeneous magnetic field. <i>Annales Henri Poincare</i>. 2004;5(4):671-741. doi:<a href=\"https://doi.org/10.1007/s00023-004-0180-x\">10.1007/s00023-004-0180-x</a>","apa":"Erdös, L., &#38; Solovej, J. (2004). Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with a strong non-homogeneous magnetic field. <i>Annales Henri Poincare</i>. Birkhäuser. <a href=\"https://doi.org/10.1007/s00023-004-0180-x\">https://doi.org/10.1007/s00023-004-0180-x</a>","ieee":"L. Erdös and J. Solovej, “Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with a strong non-homogeneous magnetic field,” <i>Annales Henri Poincare</i>, vol. 5, no. 4. Birkhäuser, pp. 671–741, 2004.","short":"L. Erdös, J. Solovej, Annales Henri Poincare 5 (2004) 671–741.","mla":"Erdös, László, and Jan Solovej. “Uniform Lieb-Thirring Inequality for the Three-Dimensional Pauli Operator with a Strong Non-Homogeneous Magnetic Field.” <i>Annales Henri Poincare</i>, vol. 5, no. 4, Birkhäuser, 2004, pp. 671–741, doi:<a href=\"https://doi.org/10.1007/s00023-004-0180-x\">10.1007/s00023-004-0180-x</a>."},"_id":"2741","volume":5,"title":"Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with a strong non-homogeneous magnetic field","quality_controlled":0,"month":"08","date_created":"2018-12-11T11:59:21Z","publist_id":"4151","doi":"10.1007/s00023-004-0180-x","publication_status":"published","type":"journal_article","publisher":"Birkhäuser","day":"01","issue":"4","status":"public","author":[{"orcid":"0000-0001-5366-9603","full_name":"László Erdös","last_name":"Erdös","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jan","last_name":"Solovej","full_name":"Solovej, Jan P"}],"publication":"Annales Henri Poincare","extern":1,"intvolume":"         5","page":"671 - 741","date_published":"2004-08-01T00:00:00Z","year":"2004","date_updated":"2021-01-12T06:59:24Z"},{"abstract":[{"lang":"eng","text":"We consider a system of N weakly interacting fermions with a real analytic pair interaction. We prove that for a general class of initial data there exists a fixed time T such that the difference between the one particle density matrix of this system and the solution of the nonlinear Hartree equation is of order N−1 for any time t⩽T."}],"citation":{"short":"A. Elgart, L. Erdös, B. Schlein, H. Yau, Journal de Mathématiques Pures et Appliquées 83 (2004) 1241–1273.","mla":"Elgart, Alexander, et al. “Nonlinear Hartree Equation as the Mean Field Limit of Weakly Coupled Fermions.” <i>Journal de Mathématiques Pures et Appliquées</i>, vol. 83, no. 10, Elsevier, 2004, pp. 1241–73, doi:<a href=\"https://doi.org/10.1016/j.matpur.2004.03.006\">10.1016/j.matpur.2004.03.006</a>.","ieee":"A. Elgart, L. Erdös, B. Schlein, and H. Yau, “Nonlinear Hartree equation as the mean field limit of weakly coupled fermions,” <i>Journal de Mathématiques Pures et Appliquées</i>, vol. 83, no. 10. Elsevier, pp. 1241–1273, 2004.","apa":"Elgart, A., Erdös, L., Schlein, B., &#38; Yau, H. (2004). Nonlinear Hartree equation as the mean field limit of weakly coupled fermions. <i>Journal de Mathématiques Pures et Appliquées</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.matpur.2004.03.006\">https://doi.org/10.1016/j.matpur.2004.03.006</a>","ama":"Elgart A, Erdös L, Schlein B, Yau H. Nonlinear Hartree equation as the mean field limit of weakly coupled fermions. <i>Journal de Mathématiques Pures et Appliquées</i>. 2004;83(10):1241-1273. doi:<a href=\"https://doi.org/10.1016/j.matpur.2004.03.006\">10.1016/j.matpur.2004.03.006</a>","ista":"Elgart A, Erdös L, Schlein B, Yau H. 2004. Nonlinear Hartree equation as the mean field limit of weakly coupled fermions. Journal de Mathématiques Pures et Appliquées. 83(10), 1241–1273.","chicago":"Elgart, Alexander, László Erdös, Benjamin Schlein, and Horng Yau. “Nonlinear Hartree Equation as the Mean Field Limit of Weakly Coupled Fermions.” <i>Journal de Mathématiques Pures et Appliquées</i>. Elsevier, 2004. <a href=\"https://doi.org/10.1016/j.matpur.2004.03.006\">https://doi.org/10.1016/j.matpur.2004.03.006</a>."},"volume":83,"_id":"2742","title":"Nonlinear Hartree equation as the mean field limit of weakly coupled fermions","quality_controlled":0,"month":"10","date_created":"2018-12-11T11:59:22Z","doi":"10.1016/j.matpur.2004.03.006","publist_id":"4150","publication_status":"published","publisher":"Elsevier","day":"01","type":"journal_article","issue":"10","status":"public","publication":"Journal de Mathématiques Pures et Appliquées","author":[{"first_name":"Alexander","full_name":"Elgart, Alexander","last_name":"Elgart"},{"full_name":"László Erdös","last_name":"Erdös","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603"},{"full_name":"Schlein, Benjamin","last_name":"Schlein","first_name":"Benjamin"},{"first_name":"Horng","full_name":"Yau, Horng-Tzer","last_name":"Yau"}],"extern":1,"intvolume":"        83","page":"1241 - 1273","date_published":"2004-10-01T00:00:00Z","year":"2004","date_updated":"2021-01-12T06:59:24Z"}]