---
_id: '17725'
abstract:
- lang: eng
text: A bright quasar residing in a dense and largely neutral intergalactic medium
(IGM) at high redshifts (z > 6) will be surrounded by a large cosmological Stromgren
sphere. The quasar's spectrum will then show a sharp increase in resonant Lyman
line absorption at wavelengths approaching and shorter than that corresponding
to the Stromgren sphere's boundary along the line of sight. We show here that
simultaneously considering the measured absorption in two or more hydrogen Lyman
lines can provide the dynamical range required to detect this feature. We model
broad and robust features of the Lyman alpha and Lyman beta regions of the spectrum
of the z=6.28 quasar SDSS J1030+0524, using a hydrodynamical simulation. From
the steep wavelength-dependence of the inferred absorption opacity, we detect
the boundary of the Stromgren sphere at a proper distance of 6.0 +/- 0.2 Mpc away
from the source redshift. From the spectrum alone, we also find that beyond this
distance, cosmic hydrogen turns nearly neutral, with a neutral fraction of x_HI
> 0.2, and that the ionizing luminosity of this quasar is in the range (5.2 +/-
2.5) times 10^{56} photons/sec. The method presented here, when applied to future
quasars, can probe the complex topology of overlapping ionized regions, and can
be used to study the details of the reionization process.
article_processing_charge: No
article_type: original
author:
- first_name: Andrei
full_name: Mesinger, Andrei
last_name: Mesinger
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
citation:
ama: Mesinger A, Haiman Z. Evidence of a cosmological Strömgren surface and of significant
neutral hydrogen surrounding the quasar SDSS J1030+0524. The Astrophysical
Journal. 2004;611(2):L69-L72. doi:10.1086/423935
apa: Mesinger, A., & Haiman, Z. (2004). Evidence of a cosmological Strömgren
surface and of significant neutral hydrogen surrounding the quasar SDSS J1030+0524.
The Astrophysical Journal. American Astronomical Society. https://doi.org/10.1086/423935
chicago: Mesinger, Andrei, and Zoltán Haiman. “Evidence of a Cosmological Strömgren
Surface and of Significant Neutral Hydrogen Surrounding the Quasar SDSS J1030+0524.”
The Astrophysical Journal. American Astronomical Society, 2004. https://doi.org/10.1086/423935.
ieee: A. Mesinger and Z. Haiman, “Evidence of a cosmological Strömgren surface and
of significant neutral hydrogen surrounding the quasar SDSS J1030+0524,” The
Astrophysical Journal, vol. 611, no. 2. American Astronomical Society, pp.
L69–L72, 2004.
ista: Mesinger A, Haiman Z. 2004. Evidence of a cosmological Strömgren surface and
of significant neutral hydrogen surrounding the quasar SDSS J1030+0524. The Astrophysical
Journal. 611(2), L69–L72.
mla: Mesinger, Andrei, and Zoltán Haiman. “Evidence of a Cosmological Strömgren
Surface and of Significant Neutral Hydrogen Surrounding the Quasar SDSS J1030+0524.”
The Astrophysical Journal, vol. 611, no. 2, American Astronomical Society,
2004, pp. L69–72, doi:10.1086/423935.
short: A. Mesinger, Z. Haiman, The Astrophysical Journal 611 (2004) L69–L72.
date_created: 2024-09-06T09:12:22Z
date_published: 2004-07-19T00:00:00Z
date_updated: 2024-09-25T14:12:20Z
day: '19'
doi: 10.1086/423935
extern: '1'
intvolume: ' 611'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/423935
month: '07'
oa: 1
oa_version: Published Version
page: L69-L72
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evidence of a cosmological Strömgren surface and of significant neutral hydrogen
surrounding the quasar SDSS J1030+0524
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 611
year: '2004'
...
---
_id: '17726'
abstract:
- lang: eng
text: We present deep unbiased spectroscopy of the Hubble Ultra Deep Field (UDF)
carried out using the slitless grism spectroscopy mode of the Advance Camera for
Surveys on the Hubble Space Telescope (HST). The GRIsm ACS Program for Extragalactic
Science (GRAPES) achieves continuum detection as faint as zAB=27.2 using 40 orbits
(9.2×10^4 seconds) on HST. The data were taken at four orientation angles to correct
for the overlap of spectra. GRAPES data provide a unique, uninterrupted, low resolution
(R=100) spectral coverage for 5500Å<λ<10500Å, and allow us to detect high redshift
galaxies at 4The Astrophysical Journal
Supplement Series. 2004;154(2):501-508. doi:10.1086/422582'
apa: 'Pirzkal, N., Xu, C., Malhotra, S., Rhoads, J. E., Koekemoer, A. M., Moustakas,
L. A., … Yan, H. (2004). GRAPES, grism spectroscopy of the hubble ultra deep field:
Description and data reduction. The Astrophysical Journal Supplement Series.
American Astronomical Society. https://doi.org/10.1086/422582'
chicago: 'Pirzkal, N., C. Xu, S. Malhotra, J. E. Rhoads, A. M. Koekemoer, L. A.
Moustakas, J. R. Walsh, et al. “GRAPES, Grism Spectroscopy of the Hubble Ultra
Deep Field: Description and Data Reduction.” The Astrophysical Journal Supplement
Series. American Astronomical Society, 2004. https://doi.org/10.1086/422582.'
ieee: 'N. Pirzkal et al., “GRAPES, grism spectroscopy of the hubble ultra
deep field: Description and data reduction,” The Astrophysical Journal Supplement
Series, vol. 154, no. 2. American Astronomical Society, pp. 501–508, 2004.'
ista: 'Pirzkal N, Xu C, Malhotra S, Rhoads JE, Koekemoer AM, Moustakas LA, Walsh
JR, Windhorst RA, Daddi E, Cimatti A, Ferguson HC, Gardner JP, Gronwall C, Haiman
Z, Kummel M, Panagia N, Pasquali A, Stiavelli M, di Serego Alighieri S, Tsvetanov
Z, Vernet J, Yan H. 2004. GRAPES, grism spectroscopy of the hubble ultra deep
field: Description and data reduction. The Astrophysical Journal Supplement Series.
154(2), 501–508.'
mla: 'Pirzkal, N., et al. “GRAPES, Grism Spectroscopy of the Hubble Ultra Deep Field:
Description and Data Reduction.” The Astrophysical Journal Supplement Series,
vol. 154, no. 2, American Astronomical Society, 2004, pp. 501–08, doi:10.1086/422582.'
short: N. Pirzkal, C. Xu, S. Malhotra, J.E. Rhoads, A.M. Koekemoer, L.A. Moustakas,
J.R. Walsh, R.A. Windhorst, E. Daddi, A. Cimatti, H.C. Ferguson, J.P. Gardner,
C. Gronwall, Z. Haiman, M. Kummel, N. Panagia, A. Pasquali, M. Stiavelli, S. di
Serego Alighieri, Z. Tsvetanov, J. Vernet, H. Yan, The Astrophysical Journal Supplement
Series 154 (2004) 501–508.
date_created: 2024-09-06T09:13:05Z
date_published: 2004-10-01T00:00:00Z
date_updated: 2024-09-25T14:30:24Z
doi: 10.1086/422582
extern: '1'
intvolume: ' 154'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/422582
month: '10'
oa: 1
oa_version: Published Version
page: 501-508
publication: The Astrophysical Journal Supplement Series
publication_identifier:
issn:
- 0067-0049
- 1538-4365
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'GRAPES, grism spectroscopy of the hubble ultra deep field: Description and
data reduction'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 154
year: '2004'
...
---
_id: '17728'
abstract:
- lang: eng
text: The cosmic ultraviolet (UV) ionizing background impacts the formation of dwarf
galaxies in the low-redshift universe (z=3) by suppressing gas infall into galactic
halos with circular velocities up to v(circ)=75 km/s. Using a one-dimensional,
spherically symmetric hydrodynamics code (Thoul & Weinberg 1995), we examine the
effect of an ionizing background on low-mass galaxies forming at high redshifts
(z>10). We find that the importance of photoionization feedback is greatly reduced,
because (1) at high redshift, dwarf-galaxy sized objects can self-shield against
the ionizing background, (2) collisional cooling processes at high redshift are
more efficient, (3) the amplitude of the ionizing background at high redshift
is lower, and (4) the ionizing radiation turns on when the perturbation that will
become the dwarf galaxy has already grown to a substantial overdensity. We find
that because of these reasons, gas can collect inside halos with circular velocities
as low as v(circ)=10 km/s. This result has important implications for the reionization
history of the universe.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Dijkstra, Mark
last_name: Dijkstra
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Martin J.
full_name: Rees, Martin J.
last_name: Rees
- first_name: David H.
full_name: Weinberg, David H.
last_name: Weinberg
citation:
ama: Dijkstra M, Haiman Z, Rees MJ, Weinberg DH. Photoionization feedback in low‐mass
galaxies at high redshift. The Astrophysical Journal. 2004;601(2):666-675.
doi:10.1086/380603
apa: Dijkstra, M., Haiman, Z., Rees, M. J., & Weinberg, D. H. (2004). Photoionization
feedback in low‐mass galaxies at high redshift. The Astrophysical Journal.
American Astronomical Society. https://doi.org/10.1086/380603
chicago: Dijkstra, Mark, Zoltán Haiman, Martin J. Rees, and David H. Weinberg. “Photoionization
Feedback in Low‐mass Galaxies at High Redshift.” The Astrophysical Journal.
American Astronomical Society, 2004. https://doi.org/10.1086/380603.
ieee: M. Dijkstra, Z. Haiman, M. J. Rees, and D. H. Weinberg, “Photoionization feedback
in low‐mass galaxies at high redshift,” The Astrophysical Journal, vol.
601, no. 2. American Astronomical Society, pp. 666–675, 2004.
ista: Dijkstra M, Haiman Z, Rees MJ, Weinberg DH. 2004. Photoionization feedback
in low‐mass galaxies at high redshift. The Astrophysical Journal. 601(2), 666–675.
mla: Dijkstra, Mark, et al. “Photoionization Feedback in Low‐mass Galaxies at High
Redshift.” The Astrophysical Journal, vol. 601, no. 2, American Astronomical
Society, 2004, pp. 666–75, doi:10.1086/380603.
short: M. Dijkstra, Z. Haiman, M.J. Rees, D.H. Weinberg, The Astrophysical Journal
601 (2004) 666–675.
date_created: 2024-09-06T09:14:46Z
date_published: 2004-02-01T00:00:00Z
date_updated: 2024-09-26T07:26:27Z
day: '01'
doi: 10.1086/380603
extern: '1'
intvolume: ' 601'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/380603
month: '02'
oa: 1
oa_version: Published Version
page: 666-675
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photoionization feedback in low‐mass galaxies at high redshift
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 601
year: '2004'
...
---
_id: '17743'
abstract:
- lang: eng
text: We use a physically motivated semi-analytic model, based on the mass function
of dark matter halos, to predict the number of radio-loud quasars as a function
of redshift and luminosity. Simple models in which the central BH mass scales
with the velocity dispersion of its host halo as M(bh) sigma(halo)^5 have been
previously found to be consistent with a number of observations, including the
optical and X-ray quasar luminosity functions. We find that similar models, when
augmented with an empirical prescription for radio emission, overpredict the number
of faint (10 micro-Jy) radio sources by 1-2 orders of magnitude. This translates
into a more stringent constraint on the low-mass end of the quasar black hole
mass function than is available from the Hubble and Chandra Deep Fields. We interpret
this discrepancy as evidence that black holes with masses below 10^7 Msun are
either rare or are not as radio-loud as their more massive counterparts. Models
that exclude BHs with masses below 10^7 Msun are in agreement with the deepest
existing radio observations, but still produce a significant tail of high-redshift
objects. In the 1-10GHz bands, at the sensitivity of 10 micro-Jy, we find surface
densities of 100, 10, and 0.3 deg^-2 for sources located at z>6, 10, and 15, respectively.
The discovery of these sources with instruments such as the Allen Telescope Array
(ATA), Extended Very Large Array (EVLA), and the Square Kilometer Array (SKA)
would open a new window for the study of supermassive BHs at high redshift. We
also find surface densities of 0.1 deg^-2 at z > 6 for mJy sources that can be
used to study 21 cm absorption from the epoch of reionization. We suggest that,
although not yet optically identified, the FIRST survey may have already detected
10^3-10^4 such sources.
article_processing_charge: No
article_type: original
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Eliot
full_name: Quataert, Eliot
last_name: Quataert
- first_name: Geoffrey C.
full_name: Bower, Geoffrey C.
last_name: Bower
citation:
ama: 'Haiman Z, Quataert E, Bower GC. Modeling the counts of faint radio‐loud quasars:
Constraints on the supermassive black hole population and predictions for high
redshift. The Astrophysical Journal. 2004;612(2):698-705. doi:10.1086/422834'
apa: 'Haiman, Z., Quataert, E., & Bower, G. C. (2004). Modeling the counts of
faint radio‐loud quasars: Constraints on the supermassive black hole population
and predictions for high redshift. The Astrophysical Journal. American
Astronomical Society. https://doi.org/10.1086/422834'
chicago: 'Haiman, Zoltán, Eliot Quataert, and Geoffrey C. Bower. “Modeling the Counts
of Faint Radio‐loud Quasars: Constraints on the Supermassive Black Hole Population
and Predictions for High Redshift.” The Astrophysical Journal. American
Astronomical Society, 2004. https://doi.org/10.1086/422834.'
ieee: 'Z. Haiman, E. Quataert, and G. C. Bower, “Modeling the counts of faint radio‐loud
quasars: Constraints on the supermassive black hole population and predictions
for high redshift,” The Astrophysical Journal, vol. 612, no. 2. American
Astronomical Society, pp. 698–705, 2004.'
ista: 'Haiman Z, Quataert E, Bower GC. 2004. Modeling the counts of faint radio‐loud
quasars: Constraints on the supermassive black hole population and predictions
for high redshift. The Astrophysical Journal. 612(2), 698–705.'
mla: 'Haiman, Zoltán, et al. “Modeling the Counts of Faint Radio‐loud Quasars: Constraints
on the Supermassive Black Hole Population and Predictions for High Redshift.”
The Astrophysical Journal, vol. 612, no. 2, American Astronomical Society,
2004, pp. 698–705, doi:10.1086/422834.'
short: Z. Haiman, E. Quataert, G.C. Bower, The Astrophysical Journal 612 (2004)
698–705.
date_created: 2024-09-06T09:27:01Z
date_published: 2004-09-10T00:00:00Z
date_updated: 2024-09-26T14:20:17Z
day: '10'
doi: 10.1086/422834
extern: '1'
intvolume: ' 612'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/422834
month: '09'
oa: 1
oa_version: Published Version
page: 698-705
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Modeling the counts of faint radio‐loud quasars: Constraints on the supermassive
black hole population and predictions for high redshift'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 612
year: '2004'
...
---
_id: '17745'
abstract:
- lang: eng
text: We quantify and discuss the footprints of neutral hydrogen in the intergalactic
medium (IGM) on the spectra of high-redshift (z ~ 6) sources, using mock spectra
generated from hydrodynamical simulations of the IGM. We show that it should be
possible to extract relevant parameters, including the mean neutral fraction in
the IGM and the radius of the local cosmological Strömgren region, from the flux
distribution in the observed spectra of distant sources. We focus on quasars,
but a similar analysis is applicable to galaxies and gamma-ray burst (GRB) afterglows.
We explicitly include uncertainties in the spectral shape of the assumed source
template near the Lyα line. Our results suggest that a mean neutral hydrogen fraction,
xH, of unity can be statistically distinguished from xH ≈ 10^-2 by combining the
spectra of tens of bright (M ≈ -27) quasars. Alternatively, the same distinction
can be achieved using the spectra of several hundred sources that are ~100 times
fainter. Furthermore, if the radius of the Strömgren sphere can be independently
constrained to within ~10%, this distinction can be achieved using a single source.
The information derived from such spectra will help in settling the current debate
as to what extent the universe was reionized at redshifts near z ~ 6.
article_processing_charge: No
article_type: original
author:
- first_name: Andrei
full_name: Mesinger, Andrei
last_name: Mesinger
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Renyue
full_name: Cen, Renyue
last_name: Cen
citation:
ama: Mesinger A, Haiman Z, Cen R. Probing the reionization history using the spectra
of high‐redshift sources. The Astrophysical Journal. 2004;613(1):23-35.
doi:10.1086/422898
apa: Mesinger, A., Haiman, Z., & Cen, R. (2004). Probing the reionization history
using the spectra of high‐redshift sources. The Astrophysical Journal.
American Astronomical Society. https://doi.org/10.1086/422898
chicago: Mesinger, Andrei, Zoltán Haiman, and Renyue Cen. “Probing the Reionization
History Using the Spectra of High‐redshift Sources.” The Astrophysical Journal.
American Astronomical Society, 2004. https://doi.org/10.1086/422898.
ieee: A. Mesinger, Z. Haiman, and R. Cen, “Probing the reionization history using
the spectra of high‐redshift sources,” The Astrophysical Journal, vol.
613, no. 1. American Astronomical Society, pp. 23–35, 2004.
ista: Mesinger A, Haiman Z, Cen R. 2004. Probing the reionization history using
the spectra of high‐redshift sources. The Astrophysical Journal. 613(1), 23–35.
mla: Mesinger, Andrei, et al. “Probing the Reionization History Using the Spectra
of High‐redshift Sources.” The Astrophysical Journal, vol. 613, no. 1,
American Astronomical Society, 2004, pp. 23–35, doi:10.1086/422898.
short: A. Mesinger, Z. Haiman, R. Cen, The Astrophysical Journal 613 (2004) 23–35.
date_created: 2024-09-06T09:34:05Z
date_published: 2004-09-20T00:00:00Z
date_updated: 2024-09-26T14:26:47Z
day: '20'
doi: 10.1086/422898
extern: '1'
intvolume: ' 613'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/422898
month: '09'
oa: 1
oa_version: Published Version
page: 23-35
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probing the reionization history using the spectra of high‐redshift sources
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 613
year: '2004'
...
---
_id: '17747'
abstract:
- lang: eng
text: Dark Energy dominates the mass-energy content of the universe (about 73%)
but we do not understand it. Most of the remainder of the Universe consists of
Dark Matter (23%), made of an unknown particle. The problem of the origin of Dark
Energy has become the biggest problem in astrophysics and one of the biggest problems
in all of science. The major extant X-ray observatories, the Chandra X-ray Observatory
and XMM-Newton, do not have the ability to perform large-area surveys of the sky.
But Dark Energy is smoothly distributed throughout the universe and the whole
universe is needed to study it. There are two basic methods to explore the properties
of Dark Energy, viz. geometrical tests (supernovae) and studies of the way in
which Dark Energy has influenced the large scale structure of the universe and
its evolution. DUO will use the latter method, employing the copious X-ray emission
from clusters of galaxies. Clusters of galaxies offer an ideal probe of cosmology
because they are the best tracers of Dark Matter and their distribution on very
large scales is dominated by the Dark Energy. In order to take the next step in
understanding Dark Energy, viz. the measurement of the 'equation of state' parameter
'w', an X-ray telescope following the design of ABRIXAS will be accommodated into
a Small Explorer mission in lowearth orbit. The telescope will perform a scan
of 6,000 sq. degs. in the area of sky covered by the Sloan Digital Sky Survey
(North), together with a deeper, smaller survey in the Southern hemisphere. DUO
will detect 10.000 clusters of galaxies, measure the number density of clusters
as a function of cosmic time, and the power spectrum of density fluctuations out
to a redshift exceeding one. When combined with the spectrum of density fluctuations
in the Cosmic Microwave Background from a redshift of 1100, this will provide
a powerful lever arm for the crucial measurement of cosmological parameters.
article_processing_charge: No
author:
- first_name: Richard
full_name: Griffiths, Richard
last_name: Griffiths
- first_name: Robert
full_name: Petre, Robert
last_name: Petre
- first_name: Guenther
full_name: Hasinger, Guenther
last_name: Hasinger
- first_name: Peter
full_name: Predehl, Peter
last_name: Predehl
- first_name: Nicholas E.
full_name: White, Nicholas E.
last_name: White
- first_name: Bernd
full_name: Aschenbach, Bernd
last_name: Aschenbach
- first_name: Xavier
full_name: Barcons, Xavier
last_name: Barcons
- first_name: Hans
full_name: Bohringer, Hans
last_name: Bohringer
- first_name: Ulrich G.
full_name: Briel, Ulrich G.
last_name: Briel
- first_name: Lynn
full_name: Cominsky, Lynn
last_name: Cominsky
- first_name: Michael F.
full_name: Corcoran, Michael F.
last_name: Corcoran
- first_name: Udo
full_name: Dinger, Udo
last_name: Dinger
- first_name: Wilhelm J.
full_name: Egle, Wilhelm J.
last_name: Egle
- first_name: Peter
full_name: Friedrich, Peter
last_name: Friedrich
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Robert
full_name: Hartmann, Robert
last_name: Hartmann
- first_name: J. Patrick
full_name: Henry, J. Patrick
last_name: Henry
- first_name: Horst
full_name: Hippmann, Horst
last_name: Hippmann
- first_name: Jim
full_name: Ingersoll, Jim
last_name: Ingersoll
- first_name: Keith
full_name: Jahoda, Keith
last_name: Jahoda
- first_name: Del T.
full_name: Jenstrom, Del T.
last_name: Jenstrom
- first_name: Steven
full_name: Jordan, Steven
last_name: Jordan
- first_name: Eckhard
full_name: Kendziorra, Eckhard
last_name: Kendziorra
- first_name: "G\x92nther"
full_name: "Kettenring, G\x92nther"
last_name: Kettenring
- first_name: Walter
full_name: Kink, Walter
last_name: Kink
- first_name: Norbert
full_name: Meidinger, Norbert
last_name: Meidinger
- first_name: Takamitsu
full_name: Miyaji, Takamitsu
last_name: Miyaji
- first_name: Joseph
full_name: Mohr, Joseph
last_name: Mohr
- first_name: Siegfried
full_name: Mueller, Siegfried
last_name: Mueller
- first_name: Richard F.
full_name: Mushotzky, Richard F.
last_name: Mushotzky
- first_name: Elmar
full_name: Pfeffermann, Elmar
last_name: Pfeffermann
- first_name: Peter
full_name: Schuecker, Peter
last_name: Schuecker
- first_name: Axel
full_name: Schwope, Axel
last_name: Schwope
- first_name: Mark
full_name: Shannon, Mark
last_name: Shannon
- first_name: Lothar
full_name: Strueder, Lothar
last_name: Strueder
- first_name: Steven J.
full_name: Varlese, Steven J.
last_name: Varlese
citation:
ama: 'Griffiths R, Petre R, Hasinger G, et al. DUO: The dark universe observatory.
In: Hasinger G, Turner MJL, eds. SPIE Astronomical Telescopes + Instrumentation.
Vol 5488. SPIE; 2004. doi:10.1117/12.552171'
apa: 'Griffiths, R., Petre, R., Hasinger, G., Predehl, P., White, N. E., Aschenbach,
B., … Varlese, S. J. (2004). DUO: The dark universe observatory. In G. Hasinger
& M. J. L. Turner (Eds.), SPIE Astronomical Telescopes + Instrumentation
(Vol. 5488). Glasgow, United Kingdom: SPIE. https://doi.org/10.1117/12.552171'
chicago: 'Griffiths, Richard, Robert Petre, Guenther Hasinger, Peter Predehl, Nicholas
E. White, Bernd Aschenbach, Xavier Barcons, et al. “DUO: The Dark Universe Observatory.”
In SPIE Astronomical Telescopes + Instrumentation, edited by Guenther Hasinger
and Martin J. L. Turner, Vol. 5488. SPIE, 2004. https://doi.org/10.1117/12.552171.'
ieee: 'R. Griffiths et al., “DUO: The dark universe observatory,” in SPIE
Astronomical Telescopes + Instrumentation, Glasgow, United Kingdom, 2004,
vol. 5488.'
ista: 'Griffiths R, Petre R, Hasinger G, Predehl P, White NE, Aschenbach B, Barcons
X, Bohringer H, Briel UG, Cominsky L, Corcoran MF, Dinger U, Egle WJ, Friedrich
P, Haiman Z, Hartmann R, Henry JP, Hippmann H, Ingersoll J, Jahoda K, Jenstrom
DT, Jordan S, Kendziorra E, Kettenring G, Kink W, Meidinger N, Miyaji T, Mohr
J, Mueller S, Mushotzky RF, Pfeffermann E, Schuecker P, Schwope A, Shannon M,
Strueder L, Varlese SJ. 2004. DUO: The dark universe observatory. SPIE Astronomical
Telescopes + Instrumentation. UV and Gamma-Ray Space Telescope Systems vol. 5488.'
mla: 'Griffiths, Richard, et al. “DUO: The Dark Universe Observatory.” SPIE Astronomical
Telescopes + Instrumentation, edited by Guenther Hasinger and Martin J. L.
Turner, vol. 5488, SPIE, 2004, doi:10.1117/12.552171.'
short: R. Griffiths, R. Petre, G. Hasinger, P. Predehl, N.E. White, B. Aschenbach,
X. Barcons, H. Bohringer, U.G. Briel, L. Cominsky, M.F. Corcoran, U. Dinger, W.J.
Egle, P. Friedrich, Z. Haiman, R. Hartmann, J.P. Henry, H. Hippmann, J. Ingersoll,
K. Jahoda, D.T. Jenstrom, S. Jordan, E. Kendziorra, G. Kettenring, W. Kink, N.
Meidinger, T. Miyaji, J. Mohr, S. Mueller, R.F. Mushotzky, E. Pfeffermann, P.
Schuecker, A. Schwope, M. Shannon, L. Strueder, S.J. Varlese, in:, G. Hasinger,
M.J.L. Turner (Eds.), SPIE Astronomical Telescopes + Instrumentation, SPIE, 2004.
conference:
end_date: 2004-06-25
location: Glasgow, United Kingdom
name: UV and Gamma-Ray Space Telescope Systems
start_date: 2004-06-21
date_created: 2024-09-06T09:35:28Z
date_published: 2004-10-11T00:00:00Z
date_updated: 2024-09-30T07:13:16Z
day: '11'
doi: 10.1117/12.552171
editor:
- first_name: Guenther
full_name: Hasinger, Guenther
last_name: Hasinger
- first_name: Martin J. L.
full_name: Turner, Martin J. L.
last_name: Turner
extern: '1'
intvolume: ' 5488'
language:
- iso: eng
main_file_link:
- url: https://doi.org/10.1117/12.552171
month: '10'
oa_version: None
publication: SPIE Astronomical Telescopes + Instrumentation
publication_identifier:
issn:
- 0277-786X
publication_status: published
publisher: SPIE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'DUO: The dark universe observatory'
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5488
year: '2004'
...
---
_id: '17758'
abstract:
- lang: eng
text: Krstic has carried out the first quantum mechanical calculations near threshold
for the charge transfer (CT) process H^+ + H_2(X ^1Sigma_g^+, nu=0, J=0) --> H(1s)
+ H_2^+. These results are relevant for models of primordial galaxy and first
star formation that require reliable atomic and molecular data for obtaining the
early universe hydrogen chemistry. Using the results of Krstic, we calculate the
relevant CT rate coefficient for temperatures between 100 and 30,000 K. We also
present a simple fit which can be readily implemented into early universe chemical
models. Additionally, we explore how the range of previously published data for
this reaction translates into uncertainties in the predicted gas temperature and
H_2 relative abundance in a collapsing primordial gas cloud. Our new data significantly
reduce these cosmological uncertainties that are due to the uncertainties in the
previously published CT rate coefficients.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel Wolf
full_name: Savin, Daniel Wolf
last_name: Savin
- first_name: Predrag S.
full_name: Krsti, Predrag S.
last_name: Krsti
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Phillip C.
full_name: Stancil, Phillip C.
last_name: Stancil
citation:
ama: Savin DW, Krsti PS, Haiman Z, Stancil PC. Rate Coefficient for H+ + H2(X1Σg+,
ν = 0, J = 0) → H(1s) + H2+ Charge Transfer and Some Cosmological Implications.
The Astrophysical Journal. 2004;606(2):L167-L170. doi:10.1086/421108
apa: Savin, D. W., Krsti, P. S., Haiman, Z., & Stancil, P. C. (2004). Rate Coefficient
for H+ + H2(X1Σg+, ν = 0, J = 0) → H(1s) + H2+ Charge Transfer and Some Cosmological
Implications. The Astrophysical Journal. American Astronomical Society.
https://doi.org/10.1086/421108
chicago: Savin, Daniel Wolf, Predrag S. Krsti, Zoltán Haiman, and Phillip C. Stancil.
“Rate Coefficient for H+ + H2(X1Σg+, ν = 0, J = 0) → H(1s) + H2+ Charge Transfer
and Some Cosmological Implications.” The Astrophysical Journal. American
Astronomical Society, 2004. https://doi.org/10.1086/421108.
ieee: D. W. Savin, P. S. Krsti, Z. Haiman, and P. C. Stancil, “Rate Coefficient
for H+ + H2(X1Σg+, ν = 0, J = 0) → H(1s) + H2+ Charge Transfer and Some Cosmological
Implications,” The Astrophysical Journal, vol. 606, no. 2. American Astronomical
Society, pp. L167–L170, 2004.
ista: Savin DW, Krsti PS, Haiman Z, Stancil PC. 2004. Rate Coefficient for H+ +
H2(X1Σg+, ν = 0, J = 0) → H(1s) + H2+ Charge Transfer and Some Cosmological Implications.
The Astrophysical Journal. 606(2), L167–L170.
mla: Savin, Daniel Wolf, et al. “Rate Coefficient for H+ + H2(X1Σg+, ν = 0, J =
0) → H(1s) + H2+ Charge Transfer and Some Cosmological Implications.” The Astrophysical
Journal, vol. 606, no. 2, American Astronomical Society, 2004, pp. L167–70,
doi:10.1086/421108.
short: D.W. Savin, P.S. Krsti, Z. Haiman, P.C. Stancil, The Astrophysical Journal
606 (2004) L167–L170.
date_created: 2024-09-06T09:45:29Z
date_published: 2004-05-10T00:00:00Z
date_updated: 2024-09-26T14:12:52Z
day: '10'
doi: 10.1086/421108
extern: '1'
intvolume: ' 606'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/421108
month: '05'
oa: 1
oa_version: Published Version
page: L167-L170
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1086/421873
scopus_import: '1'
status: public
title: Rate Coefficient for H+ + H2(X1Σg+, ν = 0, J = 0) → H(1s) + H2+ Charge Transfer
and Some Cosmological Implications
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 606
year: '2004'
...
---
_id: '17763'
abstract:
- lang: eng
text: Recent studies have suggested that during their coalescence, binary supermassive
black holes (SMBHs) experience typical gravitational recoil velocities that may
be as large as ≳100 km s^-1. These velocities exceed the escape velocity vesc
from typical dark matter (DM) halos at high redshift (z ≳ 6), and therefore put
constraints on scenarios in which early SMBHs grow at the centers of DM halos.
Here we quantify these constraints for the most distant known SMBH, with an inferred
mass in excess of 10^9 M☉, powering the bright quasar SDSS J1148+5251 discovered
in the Sloan Digital Sky Survey at z = 6.43. We assume that this SMBH grew via
a combination of accretion and mergers between preexisting seed BHs in individual
progenitor halos, and that mergers between progenitors with vesc < vkick disrupt
the BH growth process. Our results suggest that under these assumptions, the z
≈ 6 SMBHs had a phase during which they gained mass vary rapidly. In particular,
typical z ≈ 3 quasars with luminosities similar to that of SDSS J1148+5251 have
recently been inferred to have an average radiative efficiency of epsilon ≈ 20%.
The growth rate of the SMBH in SDSS J1148+5251 must have significantly exceeded
the Eddington accretion rate with this efficiency.
article_processing_charge: No
article_type: original
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
citation:
ama: Haiman Z. Constraints from gravitational recoil on the growth of supermassive
black holes at high redshift. The Astrophysical Journal. 2004;613(1):36-40.
doi:10.1086/422910
apa: Haiman, Z. (2004). Constraints from gravitational recoil on the growth of supermassive
black holes at high redshift. The Astrophysical Journal. American Astronomical
Society. https://doi.org/10.1086/422910
chicago: Haiman, Zoltán. “Constraints from Gravitational Recoil on the Growth of
Supermassive Black Holes at High Redshift.” The Astrophysical Journal.
American Astronomical Society, 2004. https://doi.org/10.1086/422910.
ieee: Z. Haiman, “Constraints from gravitational recoil on the growth of supermassive
black holes at high redshift,” The Astrophysical Journal, vol. 613, no.
1. American Astronomical Society, pp. 36–40, 2004.
ista: Haiman Z. 2004. Constraints from gravitational recoil on the growth of supermassive
black holes at high redshift. The Astrophysical Journal. 613(1), 36–40.
mla: Haiman, Zoltán. “Constraints from Gravitational Recoil on the Growth of Supermassive
Black Holes at High Redshift.” The Astrophysical Journal, vol. 613, no.
1, American Astronomical Society, 2004, pp. 36–40, doi:10.1086/422910.
short: Z. Haiman, The Astrophysical Journal 613 (2004) 36–40.
date_created: 2024-09-06T09:50:34Z
date_published: 2004-09-20T00:00:00Z
date_updated: 2024-09-30T09:12:19Z
day: '20'
doi: 10.1086/422910
extern: '1'
intvolume: ' 613'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/422910
month: '09'
oa: 1
oa_version: Published Version
page: 36-40
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Constraints from gravitational recoil on the growth of supermassive black holes
at high redshift
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 613
year: '2004'
...
---
_id: '17770'
abstract:
- lang: eng
text: "We show that the abundance and redshift distribution (\U0001D451\U0001D441/\U0001D451\U0001D467)
of galaxy clusters in future high-yield cluster surveys, combined with the spatial
power spectrum [\U0001D443\U0001D450(\U0001D458)] of the same clusters, can place
significant constraints on the evolution of the dark energy equation of state,
\U0001D464=\U0001D464(\U0001D44E). We evaluate the expected errors on \U0001D464\U0001D44E=−\U0001D451\U0001D464/\U0001D451\U0001D44E
and other cosmological parameters using a Fisher matrix approach, and simultaneously
including cluster structure evolution parameters in our analysis. We study three
different types of forthcoming surveys that will identify clusters based on their
x-ray emission (such as DUO, the Dark Universe Observatory), their Sunyaev-Zel'dovich
(SZ) decrement (such as SPT, the South Pole Telescope), or their weak-lensing
shear (such as LSST, the Large Synoptic Survey Telescope). We find that combining
the cluster abundance and power spectrum significantly enhances constraints from
either method alone. We show that the weak-lensing survey can deliver a constraint
as tight as \U0001D6E5\U0001D464\U0001D44E∼0.1 on the evolution of the dark energy
equation of state, and that the x-ray and SZ surveys each yield \U0001D6E5\U0001D464\U0001D44E∼0.4
separately, or \U0001D6E5\U0001D464\U0001D44E∼0.2 when these two surveys are
combined. For the x-ray and SZ surveys, constraints on dark energy parameters
are improved by a factor of 2 by combining the cluster data with cosmic microwave
background anisotropy measurements by Planck, but degrade by a factor of 2 if
the survey is required to solve simultaneously for cosmological and cluster structure
evolution parameters. The constraint on \U0001D464\U0001D44E from the weak-lensing
survey is improved by ∼25% with the addition of Planck data."
article_number: '123008'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sheng
full_name: Wang, Sheng
last_name: Wang
- first_name: Justin
full_name: Khoury, Justin
last_name: Khoury
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Morgan
full_name: May, Morgan
last_name: May
citation:
ama: Wang S, Khoury J, Haiman Z, May M. Constraining the evolution of dark energy
with a combination of galaxy cluster observables. Physical Review D. 2004;70(12).
doi:10.1103/physrevd.70.123008
apa: Wang, S., Khoury, J., Haiman, Z., & May, M. (2004). Constraining the evolution
of dark energy with a combination of galaxy cluster observables. Physical Review
D. American Physical Society. https://doi.org/10.1103/physrevd.70.123008
chicago: Wang, Sheng, Justin Khoury, Zoltán Haiman, and Morgan May. “Constraining
the Evolution of Dark Energy with a Combination of Galaxy Cluster Observables.”
Physical Review D. American Physical Society, 2004. https://doi.org/10.1103/physrevd.70.123008.
ieee: S. Wang, J. Khoury, Z. Haiman, and M. May, “Constraining the evolution of
dark energy with a combination of galaxy cluster observables,” Physical Review
D, vol. 70, no. 12. American Physical Society, 2004.
ista: Wang S, Khoury J, Haiman Z, May M. 2004. Constraining the evolution of dark
energy with a combination of galaxy cluster observables. Physical Review D. 70(12),
123008.
mla: Wang, Sheng, et al. “Constraining the Evolution of Dark Energy with a Combination
of Galaxy Cluster Observables.” Physical Review D, vol. 70, no. 12, 123008,
American Physical Society, 2004, doi:10.1103/physrevd.70.123008.
short: S. Wang, J. Khoury, Z. Haiman, M. May, Physical Review D 70 (2004).
date_created: 2024-09-06T10:00:53Z
date_published: 2004-12-17T00:00:00Z
date_updated: 2024-09-30T09:50:28Z
day: '17'
doi: 10.1103/physrevd.70.123008
extern: '1'
external_id:
arxiv:
- '0406331'
intvolume: ' 70'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.astro-ph/0406331'
month: '12'
oa: 1
oa_version: Preprint
publication: Physical Review D
publication_identifier:
issn:
- 1550-7998
- 1550-2368
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Constraining the evolution of dark energy with a combination of galaxy cluster
observables
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 70
year: '2004'
...
---
_id: '17775'
abstract:
- lang: eng
text: 'We discuss a simple model for the growth of supermassive black holes (BHs)
at the center of spheroidal stellar systems. In particular, we assess the hypotheses
that (1) star formation in spheroids and BH fueling are proportional to one another,
and (2) the BH accretion luminosity stays near the Eddington limit during luminous
quasar phases. With the aid of this simple model, we are able to interpret many
properties of the QSO luminosity function, including the puzzling steep decline
of the characteristic luminosity from redshift z=2 to to z=0: indeed the residual
star formation in spheroidal systems is today limited to a small number of bulges,
characterized by stellar velocity dispersions a factor of 2-3 smaller those of
the elliptical galaxies hosting QSOs at z > 2. A simple consequence of our hypotheses
is that the redshift evolution of the QSO emissivity and of the star formation
history in spheroids should be roughly parallel. We find this result to be broadly
consistent with our knowledge of the evolution of both the global star formation
rate, and of the evolution of the QSO emissivity, but we identify interesting
discrepancies at both low and high redshifts, to which we offer tentative solutions.
Finally, our hypotheses allow us to present a robust method to derive the duty
cycle of QSO activity, based on the observed QSO luminosity function, and on the
present-day relation between the masses of supermassive BHs and those of their
spheroidal host stellar systems. The duty cycle is found to be substantially less
than unity, with characteristic values in the range (3-6)x10^(-3), and we compute
that the average bolometric radiative efficiency is epsilon=0.07. Finally, we
find that the growth in mass of individual black holes at high redshift (z>2)
can be dominated by mergers, and is therefore not necessarily limited by accretion.'
article_processing_charge: No
article_type: original
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Luca
full_name: Ciotti, Luca
last_name: Ciotti
- first_name: Jeremiah P.
full_name: Ostriker, Jeremiah P.
last_name: Ostriker
citation:
ama: 'Haiman Z, Ciotti L, Ostriker JP. Reasoning from fossils: Learning from the
local black hole population about the evolution of quasars. The Astrophysical
Journal. 2004;606(2):763-773. doi:10.1086/383022'
apa: 'Haiman, Z., Ciotti, L., & Ostriker, J. P. (2004). Reasoning from fossils:
Learning from the local black hole population about the evolution of quasars.
The Astrophysical Journal. American Astronomical Society. https://doi.org/10.1086/383022'
chicago: 'Haiman, Zoltán, Luca Ciotti, and Jeremiah P. Ostriker. “Reasoning from
Fossils: Learning from the Local Black Hole Population about the Evolution of
Quasars.” The Astrophysical Journal. American Astronomical Society, 2004.
https://doi.org/10.1086/383022.'
ieee: 'Z. Haiman, L. Ciotti, and J. P. Ostriker, “Reasoning from fossils: Learning
from the local black hole population about the evolution of quasars,” The Astrophysical
Journal, vol. 606, no. 2. American Astronomical Society, pp. 763–773, 2004.'
ista: 'Haiman Z, Ciotti L, Ostriker JP. 2004. Reasoning from fossils: Learning from
the local black hole population about the evolution of quasars. The Astrophysical
Journal. 606(2), 763–773.'
mla: 'Haiman, Zoltán, et al. “Reasoning from Fossils: Learning from the Local Black
Hole Population about the Evolution of Quasars.” The Astrophysical Journal,
vol. 606, no. 2, American Astronomical Society, 2004, pp. 763–73, doi:10.1086/383022.'
short: Z. Haiman, L. Ciotti, J.P. Ostriker, The Astrophysical Journal 606 (2004)
763–773.
date_created: 2024-09-06T10:07:44Z
date_published: 2004-05-10T00:00:00Z
date_updated: 2024-09-30T11:41:03Z
day: '10'
doi: 10.1086/383022
extern: '1'
intvolume: ' 606'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/383022
month: '05'
oa: 1
oa_version: Published Version
page: 763-773
publication: The Astrophysical Journal
publication_identifier:
issn:
- 0004-637X
- 1538-4357
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Reasoning from fossils: Learning from the local black hole population about
the evolution of quasars'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 606
year: '2004'
...
---
_id: '17790'
abstract:
- lang: eng
text: Over the last few years, the Sloan Digital Sky Survey (SDSS) has discovered
several hundred quasars with redshift between 4.0 and 6.4. Including the effects
of magnification bias, one expects a priori that an appreciable fraction of these
objects are gravitationally lensed. We have used the Advanced Camera for Surveys
on the Hubble Space Telescope to carry out a snapshot imaging survey of high-redshift
SDSS quasars to search for gravitationally split lenses. This paper, the first
in a series reporting the results of the survey, describes snapshot observations
of four quasars at z = 5.74, 5.82, 5.99, and 6.30, respectively. We find that
none of these objects has a lensed companion within 5 mag with a separation larger
than 0farcs3; within 2.5 mag we can rule out companions within 0farcs1. Based
on the nondetection of strong lensing in these four systems, we constrain the
z ∼ 6 luminosity function to a slope of β > -4.63 (3 σ), assuming a break in the
quasar luminosity function at M = -24.1. We discuss the implications of this constraint
on the ionizing background due to quasars in the early universe. Given that these
quasars are not highly magnified, estimates of the masses of their central engines
by the Eddington argument must be taken seriously, possibly challenging models
of black hole formation.
article_processing_charge: No
article_type: original
author:
- first_name: Gordon T.
full_name: Richards, Gordon T.
last_name: Richards
- first_name: Michael A.
full_name: Strauss, Michael A.
last_name: Strauss
- first_name: Bartosz
full_name: Pindor, Bartosz
last_name: Pindor
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
- first_name: Xiaohui
full_name: Fan, Xiaohui
last_name: Fan
- first_name: Daniel
full_name: Eisenstein, Daniel
last_name: Eisenstein
- first_name: Donald P.
full_name: Schneider, Donald P.
last_name: Schneider
- first_name: Neta A.
full_name: Bahcall, Neta A.
last_name: Bahcall
- first_name: J.
full_name: Brinkmann, J.
last_name: Brinkmann
- first_name: Robert
full_name: Brunner, Robert
last_name: Brunner
citation:
ama: Richards GT, Strauss MA, Pindor B, et al. A snapshot survey for gravitational
lenses among z ≥ 4.0 quasars. I. The z >5.7 sample. The Astronomical Journal.
2004;127(3):1305-1312. doi:10.1086/381906
apa: Richards, G. T., Strauss, M. A., Pindor, B., Haiman, Z., Fan, X., Eisenstein,
D., … Brunner, R. (2004). A snapshot survey for gravitational lenses among z ≥
4.0 quasars. I. The z >5.7 sample. The Astronomical Journal. American
Astronomical Society. https://doi.org/10.1086/381906
chicago: Richards, Gordon T., Michael A. Strauss, Bartosz Pindor, Zoltán Haiman,
Xiaohui Fan, Daniel Eisenstein, Donald P. Schneider, Neta A. Bahcall, J. Brinkmann,
and Robert Brunner. “A Snapshot Survey for Gravitational Lenses among z ≥ 4.0
Quasars. I. The z >5.7 Sample.” The Astronomical Journal. American
Astronomical Society, 2004. https://doi.org/10.1086/381906.
ieee: G. T. Richards et al., “A snapshot survey for gravitational lenses
among z ≥ 4.0 quasars. I. The z >5.7 sample,” The Astronomical Journal,
vol. 127, no. 3. American Astronomical Society, pp. 1305–1312, 2004.
ista: Richards GT, Strauss MA, Pindor B, Haiman Z, Fan X, Eisenstein D, Schneider
DP, Bahcall NA, Brinkmann J, Brunner R. 2004. A snapshot survey for gravitational
lenses among z ≥ 4.0 quasars. I. The z >5.7 sample. The Astronomical Journal.
127(3), 1305–1312.
mla: Richards, Gordon T., et al. “A Snapshot Survey for Gravitational Lenses among
z ≥ 4.0 Quasars. I. The z >5.7 Sample.” The Astronomical Journal, vol.
127, no. 3, American Astronomical Society, 2004, pp. 1305–12, doi:10.1086/381906.
short: G.T. Richards, M.A. Strauss, B. Pindor, Z. Haiman, X. Fan, D. Eisenstein,
D.P. Schneider, N.A. Bahcall, J. Brinkmann, R. Brunner, The Astronomical Journal
127 (2004) 1305–1312.
date_created: 2024-09-06T10:22:30Z
date_published: 2004-03-01T00:00:00Z
date_updated: 2024-09-30T13:53:57Z
day: '01'
doi: 10.1086/381906
extern: '1'
intvolume: ' 127'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1086/381906
month: '03'
oa: 1
oa_version: Published Version
page: 1305-1312
publication: The Astronomical Journal
publication_identifier:
issn:
- 0004-6256
- 1538-3881
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A snapshot survey for gravitational lenses among z ≥ 4.0 quasars. I. The z
>5.7 sample
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 127
year: '2004'
...
---
_id: '17792'
abstract:
- lang: eng
text: Which came first, the stars and gas that make up a galaxy, or the giant black
hole at its centre? Observations of a distant galaxy, caught as it forms, could
help solve this chicken-and-egg problem.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
citation:
ama: Haiman Z. Caught in the act? Nature. 2004;430(7003):979-980. doi:10.1038/430979a
apa: Haiman, Z. (2004). Caught in the act? Nature. Springer Science and Business
Media LLC. https://doi.org/10.1038/430979a
chicago: Haiman, Zoltán. “Caught in the Act?” Nature. Springer Science and
Business Media LLC, 2004. https://doi.org/10.1038/430979a.
ieee: Z. Haiman, “Caught in the act?,” Nature, vol. 430, no. 7003. Springer
Science and Business Media LLC, pp. 979–980, 2004.
ista: Haiman Z. 2004. Caught in the act? Nature. 430(7003), 979–980.
mla: Haiman, Zoltán. “Caught in the Act?” Nature, vol. 430, no. 7003, Springer
Science and Business Media LLC, 2004, pp. 979–80, doi:10.1038/430979a.
short: Z. Haiman, Nature 430 (2004) 979–980.
date_created: 2024-09-06T10:24:04Z
date_published: 2004-08-25T00:00:00Z
date_updated: 2024-09-30T14:07:00Z
day: '25'
doi: 10.1038/430979a
extern: '1'
external_id:
arxiv:
- '0408479'
intvolume: ' 430'
issue: '7003'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.astro-ph/0408479'
month: '08'
oa: 1
oa_version: Preprint
page: 979-980
publication: Nature
publication_identifier:
issn:
- 0028-0836
- 1476-4687
publication_status: published
publisher: Springer Science and Business Media LLC
quality_controlled: '1'
scopus_import: '1'
status: public
title: Caught in the act?
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 430
year: '2004'
...
---
OA_place: repository
OA_type: free access
_id: '17806'
abstract:
- lang: eng
text: A population of black holes (BHs) at high redshifts (z ≳ 6) that contributes
significantly to the ionization of the intergalactic medium (IGM) would be accompanied
by the copious production of hard (≳10 keV) X-ray photons. The resulting hard
X-ray background would redshift and be observed as a present-day soft X-ray background
(SXB). Under the hypothesis that BHs are the main producers of reionizing photons
in the high-redshift universe, we calculate their contribution to the present-day
SXB. We find that accreting BHs with a hard spectrum (be it luminous quasars or
their lower mass "miniquasar" counterparts) could not fully reionize the universe
without saturating the unresolved component of the 0.5-2 keV SXB at the ≥2 σ level.
Distant miniquasars that produce enough X-rays to only partially ionize the IGM
to a level of at most xe ~ 50% saturate the unresolved SXB by ≲1 σ. Improved determinations
of the unresolved component of the SXB can provide a powerful constraint on the
contribution of accreting BHs to partial or full reionization.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Mark
full_name: Dijkstra, Mark
last_name: Dijkstra
- first_name: Zoltán
full_name: Haiman, Zoltán
id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
last_name: Haiman
orcid: 0000-0003-3633-5403
- first_name: Abraham
full_name: Loeb, Abraham
last_name: Loeb
citation:
ama: Dijkstra M, Haiman Z, Loeb A. A limit from the X‐ray background on the contribution
of quasars to reionization. The Astrophysical Journal. 2004;613(2):646-654.
doi:10.1086/422167
apa: Dijkstra, M., Haiman, Z., & Loeb, A. (2004). A limit from the X‐ray background
on the contribution of quasars to reionization. The Astrophysical Journal.
American Astronomical Society. https://doi.org/10.1086/422167
chicago: Dijkstra, Mark, Zoltán Haiman, and Abraham Loeb. “A Limit from the X‐ray
Background on the Contribution of Quasars to Reionization.” The Astrophysical
Journal. American Astronomical Society, 2004. https://doi.org/10.1086/422167.
ieee: M. Dijkstra, Z. Haiman, and A. Loeb, “A limit from the X‐ray background on
the contribution of quasars to reionization,” The Astrophysical Journal,
vol. 613, no. 2. American Astronomical Society, pp. 646–654, 2004.
ista: Dijkstra M, Haiman Z, Loeb A. 2004. A limit from the X‐ray background on the
contribution of quasars to reionization. The Astrophysical Journal. 613(2), 646–654.
mla: Dijkstra, Mark, et al. “A Limit from the X‐ray Background on the Contribution
of Quasars to Reionization.” The Astrophysical Journal, vol. 613, no. 2,
American Astronomical Society, 2004, pp. 646–54, doi:10.1086/422167.
short: M. Dijkstra, Z. Haiman, A. Loeb, The Astrophysical Journal 613 (2004) 646–654.
date_created: 2024-09-06T11:34:30Z
date_published: 2004-10-01T00:00:00Z
date_updated: 2024-11-12T10:16:58Z
day: '01'
doi: 10.1086/422167
extern: '1'
external_id:
arxiv:
- astro-ph/0403078
intvolume: ' 613'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.astro-ph/0403078
month: '10'
oa: 1
oa_version: Preprint
page: 646-654
publication: The Astrophysical Journal
publication_identifier:
eissn:
- 1538-4357
issn:
- 0004-637X
publication_status: published
publisher: American Astronomical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A limit from the X‐ray background on the contribution of quasars to reionization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 613
year: '2004'
...
---
_id: '7706'
abstract:
- lang: eng
text: 'The Sir2 deacetylase modulates organismal life-span in various species. However,
the molecular mechanisms by which Sir2 increases longevity are largely unknown.
We show that in mammalian cells, the Sir2 homolog SIRT1 appears to control the
cellular response to stress by regulating the FOXO family of Forkhead transcription
factors, a family of proteins that function as sensors of the insulin signaling
pathway and as regulators of organismal longevity. SIRT1 and the FOXO transcription
factor FOXO3 formed a complex in cells in response to oxidative stress, and SIRT1
deacetylated FOXO3 in vitro and within cells. SIRT1 had a dual effect on FOXO3
function: SIRT1 increased FOXO3''s ability to induce cell cycle arrest and resistance
to oxidative stress but inhibited FOXO3''s ability to induce cell death. Thus,
one way in which members of the Sir2 family of proteins may increase organismal
longevity is by tipping FOXO-dependent responses away from apoptosis and toward
stress resistance.'
article_processing_charge: No
article_type: original
author:
- first_name: Anne
full_name: Brunet, Anne
last_name: Brunet
- first_name: Lora Beatrice Jaeger
full_name: Sweeney, Lora Beatrice Jaeger
id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
last_name: Sweeney
orcid: 0000-0001-9242-5601
- first_name: 'J Fitzhugh '
full_name: 'Sturgill, J Fitzhugh '
last_name: Sturgill
- first_name: Katrin
full_name: Chua, Katrin
last_name: Chua
- first_name: Paul
full_name: Greer, Paul
last_name: Greer
- first_name: Yingxi
full_name: Lin, Yingxi
last_name: Lin
- first_name: Hien
full_name: Tran, Hien
last_name: Tran
- first_name: Sarah
full_name: Ross, Sarah
last_name: Ross
- first_name: Raul
full_name: Mostoslavsky, Raul
last_name: Mostoslavsky
- first_name: Haim
full_name: Cohen, Haim
last_name: Cohen
- first_name: Linda
full_name: Hu, Linda
last_name: Hu
- first_name: Hwei-Ling
full_name: Chen, Hwei-Ling
last_name: Chen
- first_name: Mark
full_name: Jedrychowski, Mark
last_name: Jedrychowski
- first_name: Steven
full_name: Gygi, Steven
last_name: Gygi
- first_name: David
full_name: Sinclair, David
last_name: Sinclair
- first_name: Frederick
full_name: Alt, Frederick
last_name: Alt
- first_name: Michael
full_name: Greenberg, Michael
last_name: Greenberg
citation:
ama: Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO
transcription factors by the SIRT1 deacetylase. Science. 2004;303(5666):2011-2015.
doi:10.1126/science.1094637
apa: Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K., Greer, P., Lin, Y.,
… Greenberg, M. (2004). Stress-dependent regulation of FOXO transcription factors
by the SIRT1 deacetylase. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1094637
chicago: Brunet, Anne, Lora B. Sweeney, J Fitzhugh Sturgill, Katrin Chua, Paul
Greer, Yingxi Lin, Hien Tran, et al. “Stress-Dependent Regulation of FOXO Transcription
Factors by the SIRT1 Deacetylase.” Science. American Association for the
Advancement of Science, 2004. https://doi.org/10.1126/science.1094637.
ieee: A. Brunet et al., “Stress-dependent regulation of FOXO transcription
factors by the SIRT1 deacetylase,” Science, vol. 303, no. 5666. American
Association for the Advancement of Science, pp. 2011–2015, 2004.
ista: Brunet A, Sweeney LB, Sturgill JF, Chua K, Greer P, Lin Y, Tran H, Ross S,
Mostoslavsky R, Cohen H, Hu L, Chen H-L, Jedrychowski M, Gygi S, Sinclair D, Alt
F, Greenberg M. 2004. Stress-dependent regulation of FOXO transcription factors
by the SIRT1 deacetylase. Science. 303(5666), 2011–2015.
mla: Brunet, Anne, et al. “Stress-Dependent Regulation of FOXO Transcription Factors
by the SIRT1 Deacetylase.” Science, vol. 303, no. 5666, American Association
for the Advancement of Science, 2004, pp. 2011–15, doi:10.1126/science.1094637.
short: A. Brunet, L.B. Sweeney, J.F. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran,
S. Ross, R. Mostoslavsky, H. Cohen, L. Hu, H.-L. Chen, M. Jedrychowski, S. Gygi,
D. Sinclair, F. Alt, M. Greenberg, Science 303 (2004) 2011–2015.
date_created: 2020-04-30T10:37:41Z
date_published: 2004-03-26T00:00:00Z
date_updated: 2024-01-31T10:14:17Z
day: '26'
doi: 10.1126/science.1094637
extern: '1'
intvolume: ' 303'
issue: '5666'
language:
- iso: eng
month: '03'
oa_version: None
page: 2011-2015
publication: Science
publication_identifier:
issn:
- 0036-8075
- 1095-9203
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 303
year: '2004'
...
---
_id: '8517'
abstract:
- lang: eng
text: We consider the evolution of a connected set on the plane carried by a space
periodic incompressible stochastic flow. While for almost every realization of
the stochastic flow at time t most of the particles are at a distance of order
equation image away from the origin, there is a measure zero set of points that
escape to infinity at the linear rate. We study the set of points visited by the
original set by time t and show that such a set, when scaled down by the factor
of t, has a limiting nonrandom shape.
article_processing_charge: No
article_type: original
author:
- first_name: Dmitry
full_name: Dolgopyat, Dmitry
last_name: Dolgopyat
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: Leonid
full_name: Koralov, Leonid
last_name: Koralov
citation:
ama: Dolgopyat D, Kaloshin V, Koralov L. A limit shape theorem for periodic stochastic
dispersion. Communications on Pure and Applied Mathematics. 2004;57(9):1127-1158.
doi:10.1002/cpa.20032
apa: Dolgopyat, D., Kaloshin, V., & Koralov, L. (2004). A limit shape theorem
for periodic stochastic dispersion. Communications on Pure and Applied Mathematics.
Wiley. https://doi.org/10.1002/cpa.20032
chicago: Dolgopyat, Dmitry, Vadim Kaloshin, and Leonid Koralov. “A Limit Shape Theorem
for Periodic Stochastic Dispersion.” Communications on Pure and Applied Mathematics.
Wiley, 2004. https://doi.org/10.1002/cpa.20032.
ieee: D. Dolgopyat, V. Kaloshin, and L. Koralov, “A limit shape theorem for periodic
stochastic dispersion,” Communications on Pure and Applied Mathematics,
vol. 57, no. 9. Wiley, pp. 1127–1158, 2004.
ista: Dolgopyat D, Kaloshin V, Koralov L. 2004. A limit shape theorem for periodic
stochastic dispersion. Communications on Pure and Applied Mathematics. 57(9),
1127–1158.
mla: Dolgopyat, Dmitry, et al. “A Limit Shape Theorem for Periodic Stochastic Dispersion.”
Communications on Pure and Applied Mathematics, vol. 57, no. 9, Wiley,
2004, pp. 1127–58, doi:10.1002/cpa.20032.
short: D. Dolgopyat, V. Kaloshin, L. Koralov, Communications on Pure and Applied
Mathematics 57 (2004) 1127–1158.
date_created: 2020-09-18T10:49:12Z
date_published: 2004-09-01T00:00:00Z
date_updated: 2021-01-12T08:19:50Z
day: '01'
doi: 10.1002/cpa.20032
extern: '1'
intvolume: ' 57'
issue: '9'
keyword:
- Applied Mathematics
- General Mathematics
language:
- iso: eng
month: '09'
oa_version: None
page: 1127-1158
publication: Communications on Pure and Applied Mathematics
publication_identifier:
issn:
- 0010-3640
- 1097-0312
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: A limit shape theorem for periodic stochastic dispersion
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2004'
...
---
_id: '8518'
article_processing_charge: No
article_type: original
author:
- first_name: Leonid
full_name: Koralov, Leonid
last_name: Koralov
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: Dmitry
full_name: Dolgopyat, Dmitry
last_name: Dolgopyat
citation:
ama: Koralov L, Kaloshin V, Dolgopyat D. Sample path properties of the stochastic
flows. The Annals of Probability. 2004;32(1A):1-27. doi:10.1214/aop/1078415827
apa: Koralov, L., Kaloshin, V., & Dolgopyat, D. (2004). Sample path properties
of the stochastic flows. The Annals of Probability. Institute of Mathematical
Statistics. https://doi.org/10.1214/aop/1078415827
chicago: Koralov, Leonid, Vadim Kaloshin, and Dmitry Dolgopyat. “Sample Path Properties
of the Stochastic Flows.” The Annals of Probability. Institute of Mathematical
Statistics, 2004. https://doi.org/10.1214/aop/1078415827.
ieee: L. Koralov, V. Kaloshin, and D. Dolgopyat, “Sample path properties of the
stochastic flows,” The Annals of Probability, vol. 32, no. 1A. Institute
of Mathematical Statistics, pp. 1–27, 2004.
ista: Koralov L, Kaloshin V, Dolgopyat D. 2004. Sample path properties of the stochastic
flows. The Annals of Probability. 32(1A), 1–27.
mla: Koralov, Leonid, et al. “Sample Path Properties of the Stochastic Flows.” The
Annals of Probability, vol. 32, no. 1A, Institute of Mathematical Statistics,
2004, pp. 1–27, doi:10.1214/aop/1078415827.
short: L. Koralov, V. Kaloshin, D. Dolgopyat, The Annals of Probability 32 (2004)
1–27.
date_created: 2020-09-18T10:49:19Z
date_published: 2004-03-04T00:00:00Z
date_updated: 2021-01-12T08:19:50Z
day: '04'
doi: 10.1214/aop/1078415827
extern: '1'
intvolume: ' 32'
issue: 1A
language:
- iso: eng
month: '03'
oa_version: None
page: 1-27
publication: The Annals of Probability
publication_identifier:
issn:
- 0091-1798
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
status: public
title: Sample path properties of the stochastic flows
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2004'
...
---
_id: '864'
abstract:
- lang: eng
text: 'We present a method for prediction of functional sites in a set of aligned
protein sequences. The method selects sites which are both well conserved and
clustered together in space, as inferred from the 3D structures of proteins included
in the alignment. We tested the method using 86 alignments from the NCBI CDD database,
where the sites of experimentally determined ligand and/or macromolecular interactions
are annotated. In agreement with earlier investigations, we found that functional
site predictions are most successful when overall background sequence conservation
is low, such that sites under evolutionary constraint become apparent. In addition,
we found that averaging of conservation values across spatially clustered sites
improves predictions under certain conditions: that is, when overall conservation
is relatively high and when the site in question involves a large macromolecular
binding interface. Under these conditions it is better to look for clusters of
conserved sites than to look for particular conserved sites.'
acknowledgement: We thank John Spouge, Ben Shoemaker, and Michael Galperin forhelpful
suggestions, and the NIH Intramural Research Program forsupport.
author:
- first_name: Anna
full_name: Panchenko, Anna R
last_name: Panchenko
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Stephen
full_name: Bryant, Stephen H
last_name: Bryant
citation:
ama: Panchenko A, Kondrashov F, Bryant S. Prediction of functional sites by analysis
of sequence and structure conservation. Protein Science. 2004;13(4):884-892.
doi:10.1110/ps.03465504
apa: Panchenko, A., Kondrashov, F., & Bryant, S. (2004). Prediction of functional
sites by analysis of sequence and structure conservation. Protein Science.
Wiley-Blackwell. https://doi.org/10.1110/ps.03465504
chicago: Panchenko, Anna, Fyodor Kondrashov, and Stephen Bryant. “Prediction of
Functional Sites by Analysis of Sequence and Structure Conservation.” Protein
Science. Wiley-Blackwell, 2004. https://doi.org/10.1110/ps.03465504.
ieee: A. Panchenko, F. Kondrashov, and S. Bryant, “Prediction of functional sites
by analysis of sequence and structure conservation,” Protein Science, vol.
13, no. 4. Wiley-Blackwell, pp. 884–892, 2004.
ista: Panchenko A, Kondrashov F, Bryant S. 2004. Prediction of functional sites
by analysis of sequence and structure conservation. Protein Science. 13(4), 884–892.
mla: Panchenko, Anna, et al. “Prediction of Functional Sites by Analysis of Sequence
and Structure Conservation.” Protein Science, vol. 13, no. 4, Wiley-Blackwell,
2004, pp. 884–92, doi:10.1110/ps.03465504.
short: A. Panchenko, F. Kondrashov, S. Bryant, Protein Science 13 (2004) 884–892.
date_created: 2018-12-11T11:48:55Z
date_published: 2004-04-01T00:00:00Z
date_updated: 2021-01-12T08:20:22Z
day: '01'
doi: 10.1110/ps.03465504
extern: 1
intvolume: ' 13'
issue: '4'
month: '04'
page: 884 - 892
publication: Protein Science
publication_status: published
publisher: Wiley-Blackwell
publist_id: '6786'
quality_controlled: 0
status: public
title: Prediction of functional sites by analysis of sequence and structure conservation
type: journal_article
volume: 13
year: '2004'
...
---
_id: '870'
abstract:
- lang: eng
text: Only a fraction of eukaryotic genes affect the phenotype drastically. We compared
18 parameters in 1273 human morbid genes, known to cause diseases, and in the
remaining 16 580 unambiguous human genes. Morbid genes evolve more slowly, have
wider phylogenetic distributions, are more similar to essential genes of Drosophila
melanogaster, code for longer proteins containing more alanine and glycine and
less histidine, lysine and methionine, possess larger numbers of longer introns
with more accurate splicing signals and have higher and broader expressions. These
differences make it possible to classify as non-morbid 34% of human genes with
unknown morbidity, when only 5% of known morbid genes are incorrectly classified
as non-morbid. This classification can help to identify disease-causing genes
among multiple candidates.
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Aleksey
full_name: Ogurtsov, Aleksey Yu
last_name: Ogurtsov
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
citation:
ama: Kondrashov F, Ogurtsov A, Kondrashov A. Bioinformatical assay of human gene
morbidity. Nucleic Acids Research. 2004;32(5):1731-1737. doi:10.1093/nar/gkh330
apa: Kondrashov, F., Ogurtsov, A., & Kondrashov, A. (2004). Bioinformatical
assay of human gene morbidity. Nucleic Acids Research. Oxford University
Press. https://doi.org/10.1093/nar/gkh330
chicago: Kondrashov, Fyodor, Aleksey Ogurtsov, and Alexey Kondrashov. “Bioinformatical
Assay of Human Gene Morbidity.” Nucleic Acids Research. Oxford University
Press, 2004. https://doi.org/10.1093/nar/gkh330.
ieee: F. Kondrashov, A. Ogurtsov, and A. Kondrashov, “Bioinformatical assay of human
gene morbidity,” Nucleic Acids Research, vol. 32, no. 5. Oxford University
Press, pp. 1731–1737, 2004.
ista: Kondrashov F, Ogurtsov A, Kondrashov A. 2004. Bioinformatical assay of human
gene morbidity. Nucleic Acids Research. 32(5), 1731–1737.
mla: Kondrashov, Fyodor, et al. “Bioinformatical Assay of Human Gene Morbidity.”
Nucleic Acids Research, vol. 32, no. 5, Oxford University Press, 2004,
pp. 1731–37, doi:10.1093/nar/gkh330.
short: F. Kondrashov, A. Ogurtsov, A. Kondrashov, Nucleic Acids Research 32 (2004)
1731–1737.
date_created: 2018-12-11T11:48:56Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2021-01-12T08:20:37Z
day: '01'
doi: 10.1093/nar/gkh330
extern: 1
intvolume: ' 32'
issue: '5'
month: '01'
page: 1731 - 1737
publication: Nucleic Acids Research
publication_status: published
publisher: Oxford University Press
publist_id: '6780'
quality_controlled: 0
status: public
title: Bioinformatical assay of human gene morbidity
type: journal_article
volume: 32
year: '2004'
...
---
_id: '875'
abstract:
- lang: eng
text: The dominance of wild-type alleles and the concomitant recessivity of deleterious
mutant alleles might have evolved by natural selection or could be a by-product
of the molecular and physiological mechanisms of gene action. We compared the
properties of human haplosufficient genes, whose wild-type alleles are dominant
over loss-of-function alleles, with haploinsufficient (recessive wild-type) genes,
which produce an abnormal phenotype when heterozygous for a loss-of-function allele.
The fraction of haplosufficient genes is the highest among the genes that encode
enzymes, which is best compatible with the physiological theory. Haploinsufficient
genes, on average, have more paralogs than haplosufficient genes, supporting the
idea that gene dosage could be important for the initial fixation of duplications.
Thus, haplo(in)sufficiency of a gene and its propensity for duplication might
have a common evolutionary basis.
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Eugene
full_name: Koonin, Eugene V
last_name: Koonin
citation:
ama: Kondrashov F, Koonin E. A common framework for understanding the origin of
genetic dominance and evolutionary fates of gene duplications. Trends in Genetics.
2004;20(7):287-291. doi:10.1016/j.tig.2004.05.001
apa: Kondrashov, F., & Koonin, E. (2004). A common framework for understanding
the origin of genetic dominance and evolutionary fates of gene duplications. Trends
in Genetics. Elsevier. https://doi.org/10.1016/j.tig.2004.05.001
chicago: Kondrashov, Fyodor, and Eugene Koonin. “A Common Framework for Understanding
the Origin of Genetic Dominance and Evolutionary Fates of Gene Duplications.”
Trends in Genetics. Elsevier, 2004. https://doi.org/10.1016/j.tig.2004.05.001.
ieee: F. Kondrashov and E. Koonin, “A common framework for understanding the origin
of genetic dominance and evolutionary fates of gene duplications,” Trends in
Genetics, vol. 20, no. 7. Elsevier, pp. 287–291, 2004.
ista: Kondrashov F, Koonin E. 2004. A common framework for understanding the origin
of genetic dominance and evolutionary fates of gene duplications. Trends in Genetics.
20(7), 287–291.
mla: Kondrashov, Fyodor, and Eugene Koonin. “A Common Framework for Understanding
the Origin of Genetic Dominance and Evolutionary Fates of Gene Duplications.”
Trends in Genetics, vol. 20, no. 7, Elsevier, 2004, pp. 287–91, doi:10.1016/j.tig.2004.05.001.
short: F. Kondrashov, E. Koonin, Trends in Genetics 20 (2004) 287–291.
date_created: 2018-12-11T11:48:58Z
date_published: 2004-07-01T00:00:00Z
date_updated: 2021-01-12T08:20:54Z
day: '01'
doi: 10.1016/j.tig.2004.05.001
extern: 1
intvolume: ' 20'
issue: '7'
month: '07'
page: 287 - 291
publication: Trends in Genetics
publication_status: published
publisher: Elsevier
publist_id: '6775'
quality_controlled: 0
status: public
title: A common framework for understanding the origin of genetic dominance and evolutionary
fates of gene duplications
type: journal_article
volume: 20
year: '2004'
...
---
_id: '889'
abstract:
- lang: eng
text: 'The function of protein and RNA molecules depends on complex epistatic interactions
between sites. Therefore, the deleterious effect of a mutation can be suppressed
by a compensatory second-site substitution. In relating a list of 86 pathogenic
mutations in human IRNAs encoded by mitochondrial genes to the sequences of their
mammalian orthologs, we noted that 52 pathogenic mutations were present in normal
tRNAs of one or several nonhuman mammals. We found at least five mechanisms of
compensation for 32 pathogenic mutations that destroyed a Watson-Crick pair in
one of the four tRNA stems: restoration of the affected Watson-Crick interaction
(25 cases), strengthening of another pair (4 cases), creation of a new pair (8
cases), changes of multiple interactions in the affected stem (11 cases) and changes
involving the interaction between the loop and stem structures (3 cases). A pathogenic
mutation and its compensating substitution are fixed in a lineage in rapid succession,
and often a compensatory interaction evolves convergently in different clades.
At least 10%, and perhaps as many as 50%, of all nucleotide substitutions in evolving
mammalian (RNAs participate in such interactions, indicating that the evolution
of tRNAs proceeds along highly epistatic fitness ridges.'
acknowledgement: We thank J. Gillespie, M. Hahn, L. Horth, A. Kondrashov, A. Kopp,
S. Nuzhdin, M. Turelli and D. Weinreich for their contributions. The authors were
supported by a grant from the US National Institutes of Health to S. Nuzhdin, and
A.D.K. is a Howard Hughes
author:
- first_name: Andrew
full_name: Kern, Andrew D
last_name: Kern
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Kern A, Kondrashov F. Mechanisms and convergence of compensatory evolution
in mammalian mitochondrial tRNAs. Nature Genetics. 2004;36(11):1207-1212.
doi:10.1038/ng1451
apa: Kern, A., & Kondrashov, F. (2004). Mechanisms and convergence of compensatory
evolution in mammalian mitochondrial tRNAs. Nature Genetics. Nature Publishing
Group. https://doi.org/10.1038/ng1451
chicago: Kern, Andrew, and Fyodor Kondrashov. “Mechanisms and Convergence of Compensatory
Evolution in Mammalian Mitochondrial TRNAs.” Nature Genetics. Nature Publishing
Group, 2004. https://doi.org/10.1038/ng1451.
ieee: A. Kern and F. Kondrashov, “Mechanisms and convergence of compensatory evolution
in mammalian mitochondrial tRNAs,” Nature Genetics, vol. 36, no. 11. Nature
Publishing Group, pp. 1207–1212, 2004.
ista: Kern A, Kondrashov F. 2004. Mechanisms and convergence of compensatory evolution
in mammalian mitochondrial tRNAs. Nature Genetics. 36(11), 1207–1212.
mla: Kern, Andrew, and Fyodor Kondrashov. “Mechanisms and Convergence of Compensatory
Evolution in Mammalian Mitochondrial TRNAs.” Nature Genetics, vol. 36,
no. 11, Nature Publishing Group, 2004, pp. 1207–12, doi:10.1038/ng1451.
short: A. Kern, F. Kondrashov, Nature Genetics 36 (2004) 1207–1212.
date_created: 2018-12-11T11:49:02Z
date_published: 2004-11-01T00:00:00Z
date_updated: 2021-01-12T08:21:17Z
day: '01'
doi: 10.1038/ng1451
extern: 1
intvolume: ' 36'
issue: '11'
month: '11'
page: 1207 - 1212
publication: Nature Genetics
publication_status: published
publisher: Nature Publishing Group
publist_id: '6759'
quality_controlled: 0
status: public
title: Mechanisms and convergence of compensatory evolution in mammalian mitochondrial
tRNAs
type: journal_article
volume: 36
year: '2004'
...