[{"publication":"Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1","author":[{"last_name":"Rother","full_name":"Rother, Carsten","first_name":"Carsten"},{"full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir"},{"last_name":"Minka","full_name":"Minka, Thomas","first_name":"Thomas"},{"first_name":"Andrew","last_name":"Blake","full_name":"Blake, Andrew"}],"citation":{"apa":"Rother, C., Kolmogorov, V., Minka, T., &#38; Blake, A. (2006). Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs. In <i>Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1</i> (pp. 993–1000). New York, NY, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2006.91\">https://doi.org/10.1109/CVPR.2006.91</a>","ama":"Rother C, Kolmogorov V, Minka T, Blake A. Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs. In: <i>Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1</i>. IEEE; 2006:993-1000. doi:<a href=\"https://doi.org/10.1109/CVPR.2006.91\">10.1109/CVPR.2006.91</a>","chicago":"Rother, Carsten, Vladimir Kolmogorov, Thomas Minka, and Andrew Blake. “Cosegmentation of Image Pairs by Histogram Matching - Incorporating a Global Constraint into MRFs.” In <i>Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1</i>, 993–1000. IEEE, 2006. <a href=\"https://doi.org/10.1109/CVPR.2006.91\">https://doi.org/10.1109/CVPR.2006.91</a>.","mla":"Rother, Carsten, et al. “Cosegmentation of Image Pairs by Histogram Matching - Incorporating a Global Constraint into MRFs.” <i>Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1</i>, IEEE, 2006, pp. 993–1000, doi:<a href=\"https://doi.org/10.1109/CVPR.2006.91\">10.1109/CVPR.2006.91</a>.","ieee":"C. Rother, V. Kolmogorov, T. Minka, and A. Blake, “Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs,” in <i>Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1</i>, New York, NY, United States, 2006, pp. 993–1000.","short":"C. Rother, V. Kolmogorov, T. Minka, A. Blake, in:, Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1, IEEE, 2006, pp. 993–1000.","ista":"Rother C, Kolmogorov V, Minka T, Blake A. 2006. Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs. Proceedings of the 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Volume 1. CVPR: Computer Vision and Pattern Recognition, 993–1000."},"_id":"3188","fulldoi":"https://doi.org/10.1109/CVPR.2006.91","page":"993 - 1000","day":"05","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","extern":"1","publist_id":"3493","OA_type":"closed access","title":"Cosegmentation of image pairs by histogram matching - Incorporating a global constraint into MRFs","publication_identifier":{"isbn":["0769525970"],"issn":["1063-6919"]},"oa_version":"None","date_updated":"2026-09-02T08:39:12Z","publication_status":"published","status":"public","date_published":"2006-07-05T00:00:00Z","language":[{"iso":"eng"}],"type":"conference","doi":"10.1109/CVPR.2006.91","date_created":"2018-12-11T12:01:54Z","month":"07","abstract":[{"text":"We introduce the term cosegmentation which denotes the task of segmenting simultaneously the common parts of an image pair. A generative model for cosegmentation is presented. Inference in the model leads to minimizing an energy with an MRF term encoding spatial coherency and a global constraint which attempts to match the appearance histograms of the common parts. This energy has not been proposed previously and its optimization is challenging and NP-hard. For this problem a novel optimization scheme which we call trust region graph cuts is presented. We demonstrate that this framework has the potential to improve a wide range of research: Object driven image retrieval, video tracking and segmentation, and interactive image editing. The power of the framework lies in its generality, the common part can be a rigid/non-rigid object (or scene), observed from different viewpoints or even similar objects of the same class.","lang":"eng"}],"conference":{"name":"CVPR: Computer Vision and Pattern Recognition","start_date":"2006-06-17","end_date":"2006-06-22","location":"New York, NY, United States"},"publisher":"IEEE","article_processing_charge":"No","year":"2006"},{"publication_identifier":{"issn":["0162-8828"],"eissn":["1939-3539"]},"oa_version":"None","extern":"1","day":"21","publist_id":"3495","fulldoi":"https://doi.org/10.1109/TPAMI.2006.200","article_type":"original","author":[{"id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov"}],"abstract":[{"text":"Algorithms for discrete energy minimization are of fundamental importance in computer vision. In this paper, we focus on the recent technique proposed by Wainwright et al. (Nov. 2005)- tree-reweighted max-product message passing (TRW). It was inspired by the problem of maximizing a lower bound on the energy. However, the algorithm is not guaranteed to increase this bound - it may actually go down. In addition, TRW does not always converge. We develop a modification of this algorithm which we call sequential tree-reweighted message passing. Its main property is that the bound is guaranteed not to decrease. We also give a weak tree agreement condition which characterizes local maxima of the bound with respect to TRW algorithms. We prove that our algorithm has a limit point that achieves weak tree agreement. Finally, we show that, our algorithm requires half as much memory as traditional message passing approaches. Experimental results demonstrate that on certain synthetic and real problems, our algorithm outperforms both the ordinary belief propagation and tree-reweighted algorithm in (M. J. Wainwright, et al., Nov. 2005). In addition, on stereo problems with Potts interactions, we obtain a lower energy than graph cuts.","lang":"eng"}],"article_processing_charge":"No","year":"2006","publisher":"IEEE","month":"08","type":"journal_article","publication_status":"published","date_published":"2006-08-21T00:00:00Z","status":"public","title":"Convergent tree reweighted message passing for energy minimization","OA_type":"closed access","date_updated":"2026-09-02T08:46:06Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","main_file_link":[{"url":"http://research.microsoft.com/pubs/67371/trw_maxproduct_aistats05.pdf"}],"volume":28,"_id":"3190","page":"1568 - 1583","publication":"IEEE Transactions on Pattern Analysis and Machine Intelligence","citation":{"chicago":"Kolmogorov, Vladimir. “Convergent Tree Reweighted Message Passing for Energy Minimization.” <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>. IEEE, 2006. <a href=\"https://doi.org/10.1109/TPAMI.2006.200\">https://doi.org/10.1109/TPAMI.2006.200</a>.","ama":"Kolmogorov V. Convergent tree reweighted message passing for energy minimization. <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>. 2006;28(10):1568-1583. doi:<a href=\"https://doi.org/10.1109/TPAMI.2006.200\">10.1109/TPAMI.2006.200</a>","apa":"Kolmogorov, V. (2006). Convergent tree reweighted message passing for energy minimization. <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>. IEEE. <a href=\"https://doi.org/10.1109/TPAMI.2006.200\">https://doi.org/10.1109/TPAMI.2006.200</a>","ista":"Kolmogorov V. 2006. Convergent tree reweighted message passing for energy minimization. IEEE Transactions on Pattern Analysis and Machine Intelligence. 28(10), 1568–1583.","short":"V. Kolmogorov, IEEE Transactions on Pattern Analysis and Machine Intelligence 28 (2006) 1568–1583.","ieee":"V. Kolmogorov, “Convergent tree reweighted message passing for energy minimization,” <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>, vol. 28, no. 10. IEEE, pp. 1568–1583, 2006.","mla":"Kolmogorov, Vladimir. “Convergent Tree Reweighted Message Passing for Energy Minimization.” <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>, vol. 28, no. 10, IEEE, 2006, pp. 1568–83, doi:<a href=\"https://doi.org/10.1109/TPAMI.2006.200\">10.1109/TPAMI.2006.200</a>."},"pmid":1,"external_id":{"pmid":["16986540"]},"issue":"10","date_created":"2018-12-11T12:01:55Z","language":[{"iso":"eng"}],"doi":"10.1109/TPAMI.2006.200","intvolume":"        28"},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","main_file_link":[{"url":"http://research-srv.microsoft.com/pubs/67896/szsvkatr-eccv06.pdf"}],"OA_type":"closed access","title":"A comparative study of energy minimization methods for Markov random fields","date_updated":"2026-09-02T09:35:16Z","publication":"Proceedings of the 9th European conference on Computer Vision - Volume Part II","citation":{"ama":"Szeliski R, Zabih R, Scharstein D, et al. A comparative study of energy minimization methods for Markov random fields. In: <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>. Vol 3952. Springer Nature; 2006:16-29. doi:<a href=\"https://doi.org/10.1007/11744047_2\">10.1007/11744047_2</a>","chicago":"Szeliski, Richard, Ramin Zabih, Daniel Scharstein, Olga Veksler, Vladimir Kolmogorov, Aseem Agarwala, Marshall Tappen, and Carsten Rother. “A Comparative Study of Energy Minimization Methods for Markov Random Fields.” In <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>, 3952:16–29. Springer Nature, 2006. <a href=\"https://doi.org/10.1007/11744047_2\">https://doi.org/10.1007/11744047_2</a>.","apa":"Szeliski, R., Zabih, R., Scharstein, D., Veksler, O., Kolmogorov, V., Agarwala, A., … Rother, C. (2006). A comparative study of energy minimization methods for Markov random fields. In <i>Proceedings of the 9th European conference on Computer Vision - Volume Part II</i> (Vol. 3952, pp. 16–29). Graz, Austria: Springer Nature. <a href=\"https://doi.org/10.1007/11744047_2\">https://doi.org/10.1007/11744047_2</a>","short":"R. Szeliski, R. Zabih, D. Scharstein, O. Veksler, V. Kolmogorov, A. Agarwala, M. Tappen, C. Rother, in:, Proceedings of the 9th European Conference on Computer Vision - Volume Part II, Springer Nature, 2006, pp. 16–29.","ista":"Szeliski R, Zabih R, Scharstein D, Veksler O, Kolmogorov V, Agarwala A, Tappen M, Rother C. 2006. A comparative study of energy minimization methods for Markov random fields. Proceedings of the 9th European conference on Computer Vision - Volume Part II. ECCV: European Conference on Computer Vision vol. 3952, 16–29.","ieee":"R. Szeliski <i>et al.</i>, “A comparative study of energy minimization methods for Markov random fields,” in <i>Proceedings of the 9th European conference on Computer Vision - Volume Part II</i>, Graz, Austria, 2006, vol. 3952, pp. 16–29.","mla":"Szeliski, Richard, et al. “A Comparative Study of Energy Minimization Methods for Markov Random Fields.” <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>, vol. 3952, Springer Nature, 2006, pp. 16–29, doi:<a href=\"https://doi.org/10.1007/11744047_2\">10.1007/11744047_2</a>."},"_id":"3180","volume":3952,"page":"16 - 29","date_created":"2018-12-11T12:01:51Z","intvolume":"      3952","language":[{"iso":"eng"}],"doi":"10.1007/11744047_2","extern":"1","day":"03","publist_id":"3499","publication_identifier":{"isbn":["9783540338345"],"eisbn":["9783540338352"]},"oa_version":"None","author":[{"last_name":"Szeliski","full_name":"Szeliski, Richard","first_name":"Richard"},{"first_name":"Ramin","full_name":"Zabih, Ramin","last_name":"Zabih"},{"first_name":"Daniel","last_name":"Scharstein","full_name":"Scharstein, Daniel"},{"first_name":"Olga","full_name":"Veksler, Olga","last_name":"Veksler"},{"full_name":"Kolmogorov, Vladimir","last_name":"Kolmogorov","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Agarwala, Aseem","last_name":"Agarwala","first_name":"Aseem"},{"full_name":"Tappen, Marshall","last_name":"Tappen","first_name":"Marshall"},{"first_name":"Carsten","last_name":"Rother","full_name":"Rother, Carsten"}],"fulldoi":"https://doi.org/10.1007/11744047_2","month":"05","conference":{"name":"ECCV: European Conference on Computer Vision","end_date":"2006-05-13","start_date":"2006-05-07","location":"Graz, Austria"},"abstract":[{"text":"One of the most exciting advances in early vision has been the development of efficient energy minimization algorithms. Many early vision tasks require labeling each pixel with some quantity such as depth or texture. While many such problems can be elegantly expressed in the language of Markov Random Fields (MRF's), the resulting energy minimization problems were widely viewed as intractable. Recently, algorithms such as graph cuts and loopy belief propagation (LBP) have proven to be very powerful: for example, such methods form the basis for almost all the top-performing stereo methods. Unfortunately, most papers define their own energy function, which is minimized with a specific algorithm of their choice. As a result, the tradeoffs among different energy minimization algorithms are not well understood. In this paper we describe a set of energy minimization benchmarks, which we use to compare the solution quality and running time of several common energy minimization algorithms. We investigate three promising recent methods - graph cuts, LBP, and tree-reweighted message passing - as well as the well-known older iterated conditional modes (ICM) algorithm. Our benchmark problems are drawn from published energy functions used for stereo, image stitching and interactive segmentation. We also provide a general-purpose software interface that allows vision researchers to easily switch between optimization methods with minimal overhead. We expect that the availability of our benchmarks and interface will make it significantly easier for vision researchers to adopt the best method for their specific problems. Benchmarks, code, results and images are available at http://vision.middlebury.edu/MRF.","lang":"eng"}],"article_processing_charge":"No","year":"2006","publisher":"Springer Nature","publication_status":"published","date_published":"2006-05-03T00:00:00Z","status":"public","type":"conference"},{"alternative_title":["LNCS"],"author":[{"last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir","first_name":"Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Rother","full_name":"Rother, Carsten","first_name":"Carsten"}],"fulldoi":"https://doi.org/10.1007/11744047_1","day":"03","extern":"1","publist_id":"3498","publication_identifier":{"eisbn":["9783540338352"],"isbn":["9783540338345"]},"oa_version":"None","publication_status":"published","date_published":"2006-05-03T00:00:00Z","status":"public","type":"conference","month":"05","abstract":[{"text":"Algorithms for discrete energy minimization play a fundamental role for low-level vision. Known techniques include graph cuts, belief propagation (BP) and recently introduced tree-reweighted message passing (TRW). So far, the standard benchmark for their comparison has been a 4-connected grid-graph arising in pixel-labelling stereo. This minimization problem, however, has been largely solved: recent work shows that for many scenes TRW finds the global optimum. Furthermore, it is known that a 4-connecled grid-graph is a poor stereo model since it does not take occlusions into account. We propose the problem of stereo with occlusions as a new test bed for minimization algorithms. This is a more challenging graph since it has much larger connectivity, and it also serves as a better stereo model. An attractive feature of this problem is that increased connectivity does not result in increased complexity of message passing algorithms. Indeed, one contribution of this paper is to show that sophisticated implementations of BP and TRW have the same time and memory complexity as that of 4-connecled grid-graph stereo. The main conclusion of our experimental study is that for our problem graph cut outperforms both TRW and BP considerably. TRW achieves consistently a lower energy than BP. However, as connectivity increases the speed of convergence of TRW becomes slower. Unlike 4-connected grids, the difference between the energy of the best optimization method and the lower bound of TRW appears significant. This shows the hardness of the problem and motivates future research.","lang":"eng"}],"conference":{"name":"ECCV: European Conference on Computer Vision","location":"Graz, Austria","end_date":"2006-05-13","start_date":"2006-05-07"},"publisher":"Springer Nature","article_processing_charge":"No","year":"2006","publication":"Proceedings of the 9th European conference on Computer Vision - Volume Part II","citation":{"chicago":"Kolmogorov, Vladimir, and Carsten Rother. “Comparison of Energy Minimization Algorithms for Highly Connected Graphs.” In <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>, 3952 LNCS:1–15. Springer Nature, 2006. <a href=\"https://doi.org/10.1007/11744047_1\">https://doi.org/10.1007/11744047_1</a>.","ama":"Kolmogorov V, Rother C. Comparison of energy minimization algorithms for highly connected graphs. In: <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>. Vol 3952 LNCS. Springer Nature; 2006:1-15. doi:<a href=\"https://doi.org/10.1007/11744047_1\">10.1007/11744047_1</a>","apa":"Kolmogorov, V., &#38; Rother, C. (2006). Comparison of energy minimization algorithms for highly connected graphs. In <i>Proceedings of the 9th European conference on Computer Vision - Volume Part II</i> (Vol. 3952 LNCS, pp. 1–15). Graz, Austria: Springer Nature. <a href=\"https://doi.org/10.1007/11744047_1\">https://doi.org/10.1007/11744047_1</a>","ista":"Kolmogorov V, Rother C. 2006. Comparison of energy minimization algorithms for highly connected graphs. Proceedings of the 9th European conference on Computer Vision - Volume Part II. ECCV: European Conference on Computer Vision, LNCS, vol. 3952 LNCS, 1–15.","short":"V. Kolmogorov, C. Rother, in:, Proceedings of the 9th European Conference on Computer Vision - Volume Part II, Springer Nature, 2006, pp. 1–15.","mla":"Kolmogorov, Vladimir, and Carsten Rother. “Comparison of Energy Minimization Algorithms for Highly Connected Graphs.” <i>Proceedings of the 9th European Conference on Computer Vision - Volume Part II</i>, vol. 3952 LNCS, Springer Nature, 2006, pp. 1–15, doi:<a href=\"https://doi.org/10.1007/11744047_1\">10.1007/11744047_1</a>.","ieee":"V. Kolmogorov and C. Rother, “Comparison of energy minimization algorithms for highly connected graphs,” in <i>Proceedings of the 9th European conference on Computer Vision - Volume Part II</i>, Graz, Austria, 2006, vol. 3952 LNCS, pp. 1–15."},"volume":"3952 LNCS","_id":"3184","page":"1 - 15","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","main_file_link":[{"url":"http://research.microsoft.com/pubs/67889/paper_eccv06-trw.pdf"}],"title":"Comparison of energy minimization algorithms for highly connected graphs","OA_type":"closed access","date_updated":"2026-09-02T09:31:12Z","language":[{"iso":"eng"}],"doi":"10.1007/11744047_1","date_created":"2018-12-11T12:01:52Z"},{"external_id":{"pmid":["17043314"]},"pmid":1,"issue":"20","date_created":"2018-12-11T12:00:53Z","language":[{"iso":"eng"}],"doi":"10.1101/gad.390806","intvolume":"        20","OA_type":"closed access","title":"Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity","date_updated":"2026-09-02T13:12:54Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","_id":"3016","volume":20,"page":"2902 - 2911","publication":"Genes and Development","citation":{"chicago":"Sauer, Michael, Jozef Balla, Christian Luschnig, Justyna Wiśniewska, Vilém Reinöhl, Jiří Friml, and Eva Benková. “Canalization of Auxin Flow by Aux/IAA-ARF-Dependent Feedback Regulation of PIN Polarity.” <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press, 2006. <a href=\"https://doi.org/10.1101/gad.390806\">https://doi.org/10.1101/gad.390806</a>.","ama":"Sauer M, Balla J, Luschnig C, et al. Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. <i>Genes and Development</i>. 2006;20(20):2902-2911. doi:<a href=\"https://doi.org/10.1101/gad.390806\">10.1101/gad.390806</a>","apa":"Sauer, M., Balla, J., Luschnig, C., Wiśniewska, J., Reinöhl, V., Friml, J., &#38; Benková, E. (2006). Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press. <a href=\"https://doi.org/10.1101/gad.390806\">https://doi.org/10.1101/gad.390806</a>","ista":"Sauer M, Balla J, Luschnig C, Wiśniewska J, Reinöhl V, Friml J, Benková E. 2006. Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity. Genes and Development. 20(20), 2902–2911.","short":"M. Sauer, J. Balla, C. Luschnig, J. Wiśniewska, V. Reinöhl, J. Friml, E. Benková, Genes and Development 20 (2006) 2902–2911.","mla":"Sauer, Michael, et al. “Canalization of Auxin Flow by Aux/IAA-ARF-Dependent Feedback Regulation of PIN Polarity.” <i>Genes and Development</i>, vol. 20, no. 20, Cold Spring Harbor Laboratory Press, 2006, pp. 2902–11, doi:<a href=\"https://doi.org/10.1101/gad.390806\">10.1101/gad.390806</a>.","ieee":"M. Sauer <i>et al.</i>, “Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity,” <i>Genes and Development</i>, vol. 20, no. 20. Cold Spring Harbor Laboratory Press, pp. 2902–2911, 2006."},"abstract":[{"text":"Plant development is characterized by a profound ability to regenerate and form tissues with new axes of polarity. An unsolved question concerns how the position within a tissue and cues from neighboring cells are integrated to specify the polarity of individual cells. The canalization hypothesis proposes a feedback effect of the phytohormone auxin on the directionality of intercellular auxin flow as a means to polarize tissues. Here we identify a cellular and molecular mechanism for canalization. Local auxin application, wounding, or auxin accumulation during de novo organ formation lead to rearrangements in the subcellular polar localization of PIN auxin transport components. This auxin effect on PIN polarity is cell-specific, does not depend on PIN transcription, and involves the Aux/IAA-ARF (indole-3-acetic acid-auxin response factor) signaling pathway. Our data suggest that auxin acts as polarizing cue, which links individual cell polarity with tissue and organ polarity through control of PIN polar targeting. This feedback regulation provides a conceptual framework for polarization during multiple regenerative and patterning processes in plants.","lang":"eng"}],"publisher":"Cold Spring Harbor Laboratory Press","year":"2006","article_processing_charge":"No","month":"10","type":"journal_article","publication_status":"published","status":"public","date_published":"2006-10-15T00:00:00Z","publication_identifier":{"issn":["0890-9369"],"eissn":["1549-5477"]},"oa_version":"None","day":"15","extern":"1","publist_id":"3686","fulldoi":"https://doi.org/10.1101/gad.390806","article_type":"original","author":[{"first_name":"Michael","full_name":"Sauer, Michael","last_name":"Sauer"},{"last_name":"Balla","full_name":"Balla, Jozef","first_name":"Jozef"},{"last_name":"Luschnig","full_name":"Luschnig, Christian","first_name":"Christian"},{"first_name":"Justyna","last_name":"Wiśniewska","full_name":"Wiśniewska, Justyna"},{"full_name":"Reinöhl, Vilém","last_name":"Reinöhl","first_name":"Vilém"},{"full_name":"Friml, Jirí","last_name":"Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Benková, Eva","last_name":"Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","first_name":"Eva"}],"related_material":{"link":[{"relation":"erratum","url":"http://genesdev.cshlp.org/content/21/11/1431.short"}]}},{"date_updated":"2026-09-02T13:09:55Z","OA_type":"closed access","title":"Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","page":"3171 - 3181","volume":18,"_id":"3018","citation":{"ista":"Kleine Vehn J, Dhonukshe P, Swarup R, Bennett M, Friml J. 2006. Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell. 18(11), 3171–3181.","short":"J. Kleine Vehn, P. Dhonukshe, R. Swarup, M. Bennett, J. Friml, Plant Cell 18 (2006) 3171–3181.","ieee":"J. Kleine Vehn, P. Dhonukshe, R. Swarup, M. Bennett, and J. Friml, “Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1,” <i>Plant Cell</i>, vol. 18, no. 11. American Society of Plant Biologists, pp. 3171–3181, 2006.","mla":"Kleine Vehn, Jürgen, et al. “Subcellular Trafficking of the Arabidopsis Auxin Influx Carrier AUX1 Uses a Novel Pathway Distinct from PIN1.” <i>Plant Cell</i>, vol. 18, no. 11, American Society of Plant Biologists, 2006, pp. 3171–81, doi:<a href=\"https://doi.org/10.1105/tpc.106.042770\">10.1105/tpc.106.042770</a>.","chicago":"Kleine Vehn, Jürgen, Pankaj Dhonukshe, Ranjan Swarup, Malcolm Bennett, and Jiří Friml. “Subcellular Trafficking of the Arabidopsis Auxin Influx Carrier AUX1 Uses a Novel Pathway Distinct from PIN1.” <i>Plant Cell</i>. American Society of Plant Biologists, 2006. <a href=\"https://doi.org/10.1105/tpc.106.042770\">https://doi.org/10.1105/tpc.106.042770</a>.","ama":"Kleine Vehn J, Dhonukshe P, Swarup R, Bennett M, Friml J. Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. <i>Plant Cell</i>. 2006;18(11):3171-3181. doi:<a href=\"https://doi.org/10.1105/tpc.106.042770\">10.1105/tpc.106.042770</a>","apa":"Kleine Vehn, J., Dhonukshe, P., Swarup, R., Bennett, M., &#38; Friml, J. (2006). Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. <i>Plant Cell</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1105/tpc.106.042770\">https://doi.org/10.1105/tpc.106.042770</a>"},"publication":"Plant Cell","issue":"11","external_id":{"pmid":["17114355"]},"pmid":1,"date_created":"2018-12-11T12:00:53Z","doi":"10.1105/tpc.106.042770","language":[{"iso":"eng"}],"intvolume":"        18","oa_version":"None","publication_identifier":{"issn":["1040-4651"],"eissn":["1532-298X"]},"publist_id":"3684","day":"01","extern":"1","fulldoi":"https://doi.org/10.1105/tpc.106.042770","author":[{"last_name":"Kleine Vehn","full_name":"Kleine Vehn, Jürgen","first_name":"Jürgen"},{"first_name":"Pankaj","last_name":"Dhonukshe","full_name":"Dhonukshe, Pankaj"},{"last_name":"Swarup","full_name":"Swarup, Ranjan","first_name":"Ranjan"},{"full_name":"Bennett, Malcolm","last_name":"Bennett","first_name":"Malcolm"},{"first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jirí","last_name":"Friml"}],"article_type":"original","publisher":"American Society of Plant Biologists","year":"2006","article_processing_charge":"No","abstract":[{"text":"The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components underpins the directionality of intercellular auxin flow in Arabidopsis thaliana roots. Here, we examined the mechanism of polar trafficking of AUX1. Real-time live cell analysis along with subcellular markers revealed that AUX1 resides at the apical plasma membrane of protophloem cells and at highly dynamic subpopulations of Golgi apparatus and endosomes in all cell types. Plasma membrane and intracellular pools of AUX1 are interconnected by actin-dependent constitutive trafficking, which is not sensitive to the vesicle trafficking inhibitor brefeldin A. AUX1 subcellular dynamics are not influenced by the auxin influx inhibitor NOA but are blocked by the auxin efflux inhibitors TIBA and PBA. Furthermore, auxin transport inhibitors and interference with the sterol composition of membranes disrupt polar AUX1 distribution at the plasma membrane. Compared with PIN1 trafficking, AUX1 dynamics display different sensitivities to trafficking inhibitors and are independent of the endosomal trafficking regulator ARF GEF GNOM. Hence, AUX1 uses a novel trafficking pathway in plants that is distinct from PIN trafficking, providing an additional mechanism for the fine regulation of auxin transport.","lang":"eng"}],"month":"11","type":"journal_article","status":"public","date_published":"2006-11-01T00:00:00Z","publication_status":"published"},{"publication_status":"published","date_published":"2006-11-01T00:00:00Z","status":"public","type":"journal_article","month":"11","abstract":[{"text":"High throughput microarray transcription analyses provide us with the expression profiles for large amounts of plant genes. However, their tissue and cellular resolution is limited. Thus, for detailed functional analysis, it is still necessary to examine the expression pattern of selected candidate genes at a cellular level. Here, we present an in situ mRNA hybridization method that is routinely used for the analysis of plant gene expression patterns. The protocol is optimized for whole mount mRNA localizations in Arabidopsis seedling tissues including embryos, roots, hypocotyls and young primary leaves. It can also be used for comparable tissues in other species. Part of the protocol can also be automated and performed by a liquid handling robot. Here we present a detailed protocol, recommended controls and troubleshooting, along with examples of several applications. The total time to carry out the entire procedure is ∼7 d, depending on the tissue used.","lang":"eng"}],"year":"2006","article_processing_charge":"No","publisher":"Nature Publishing Group","article_type":"original","author":[{"full_name":"Hejátko, Jan","last_name":"Hejátko","first_name":"Jan"},{"full_name":"Blilou, Ikram","last_name":"Blilou","first_name":"Ikram"},{"last_name":"Brewer","full_name":"Brewer, Philip","first_name":"Philip"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jirí"},{"first_name":"Ben","last_name":"Scheres","full_name":"Scheres, Ben"},{"full_name":"Benková, Eva","last_name":"Benková","orcid":"0000-0002-8510-9739","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}],"fulldoi":"https://doi.org/10.1038/nprot.2006.333","extern":"1","day":"01","publist_id":"3683","publication_identifier":{"issn":["1754-2189"],"eissn":["1750-2799"]},"oa_version":"None","intvolume":"         1","language":[{"iso":"eng"}],"doi":"10.1038/nprot.2006.333","date_created":"2018-12-11T12:00:54Z","pmid":1,"external_id":{"pmid":["17487180"]},"issue":"4","publication":"Nature Protocols","citation":{"apa":"Hejátko, J., Blilou, I., Brewer, P., Friml, J., Scheres, B., &#38; Benková, E. (2006). In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. <i>Nature Protocols</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nprot.2006.333\">https://doi.org/10.1038/nprot.2006.333</a>","chicago":"Hejátko, Jan, Ikram Blilou, Philip Brewer, Jiří Friml, Ben Scheres, and Eva Benková. “In Situ Hybridization Technique for MRNA Detection in Whole Mount Arabidopsis Samples.” <i>Nature Protocols</i>. Nature Publishing Group, 2006. <a href=\"https://doi.org/10.1038/nprot.2006.333\">https://doi.org/10.1038/nprot.2006.333</a>.","ama":"Hejátko J, Blilou I, Brewer P, Friml J, Scheres B, Benková E. In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. <i>Nature Protocols</i>. 2006;1(4):1939-1946. doi:<a href=\"https://doi.org/10.1038/nprot.2006.333\">10.1038/nprot.2006.333</a>","mla":"Hejátko, Jan, et al. “In Situ Hybridization Technique for MRNA Detection in Whole Mount Arabidopsis Samples.” <i>Nature Protocols</i>, vol. 1, no. 4, Nature Publishing Group, 2006, pp. 1939–46, doi:<a href=\"https://doi.org/10.1038/nprot.2006.333\">10.1038/nprot.2006.333</a>.","ieee":"J. Hejátko, I. Blilou, P. Brewer, J. Friml, B. Scheres, and E. Benková, “In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples,” <i>Nature Protocols</i>, vol. 1, no. 4. Nature Publishing Group, pp. 1939–1946, 2006.","ista":"Hejátko J, Blilou I, Brewer P, Friml J, Scheres B, Benková E. 2006. In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples. Nature Protocols. 1(4), 1939–1946.","short":"J. Hejátko, I. Blilou, P. Brewer, J. Friml, B. Scheres, E. Benková, Nature Protocols 1 (2006) 1939–1946."},"_id":"3020","volume":1,"page":"1939 - 1946","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_type":"closed access","title":"In situ hybridization technique for mRNA detection in whole mount Arabidopsis samples","date_updated":"2026-09-02T13:07:19Z"},{"extern":"1","day":"01","publist_id":"3688","publication_identifier":{"issn":["1754-2189"],"eissn":["1750-2799"]},"oa_version":"None","article_type":"original","author":[{"first_name":"Michael","full_name":"Sauer, Michael","last_name":"Sauer"},{"last_name":"Paciorek","full_name":"Paciorek, Tomasz","first_name":"Tomasz"},{"orcid":"0000-0002-8510-9739","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","full_name":"Benková, Eva"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","first_name":"Jirí","full_name":"Friml, Jirí","last_name":"Friml"}],"fulldoi":"https://doi.org/10.1038/nprot.2006.15","month":"06","abstract":[{"text":"As the field of plant molecular biology is swiftly advancing, a need has been created for methods that allow rapid and reliable in situ localization of proteins in plant cells. Here we describe a whole-mount 'immunolocalization' technique for various plant tissues, including roots, hypocotyls, cotyledons, young primary leaves and embryos of Arabidopsis thaliana and other species. The detailed protocol, recommended controls and troubleshooting are presented, along with examples of applications. The protocol consists of five main procedures: tissue fixation, tissue permeation, blocking, primary and secondary antibody incubation. Notably, the first procedure (tissue fixation) includes several steps (4-12) that are absolutely necessary for protein localization in hypocotyls, cotyledons and young primary leaves but should be omitted for other tissues. The protocol is usually done in 3 days, but could also be completed in 2 days.","lang":"eng"}],"year":"2006","article_processing_charge":"No","publisher":"Nature Publishing Group","publication_status":"published","status":"public","date_published":"2006-06-01T00:00:00Z","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Immunocytochemical techniques for whole mount in situ protein localization in plants","OA_type":"closed access","date_updated":"2026-09-02T13:17:35Z","publication":"Nature Protocols","citation":{"ieee":"M. Sauer, T. Paciorek, E. Benková, and J. Friml, “Immunocytochemical techniques for whole mount in situ protein localization in plants,” <i>Nature Protocols</i>, vol. 1, no. 1. Nature Publishing Group, pp. 98–103, 2006.","mla":"Sauer, Michael, et al. “Immunocytochemical Techniques for Whole Mount in Situ Protein Localization in Plants.” <i>Nature Protocols</i>, vol. 1, no. 1, Nature Publishing Group, 2006, pp. 98–103, doi:<a href=\"https://doi.org/10.1038/nprot.2006.15\">10.1038/nprot.2006.15</a>.","ista":"Sauer M, Paciorek T, Benková E, Friml J. 2006. Immunocytochemical techniques for whole mount in situ protein localization in plants. Nature Protocols. 1(1), 98–103.","short":"M. Sauer, T. Paciorek, E. Benková, J. Friml, Nature Protocols 1 (2006) 98–103.","apa":"Sauer, M., Paciorek, T., Benková, E., &#38; Friml, J. (2006). Immunocytochemical techniques for whole mount in situ protein localization in plants. <i>Nature Protocols</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nprot.2006.15\">https://doi.org/10.1038/nprot.2006.15</a>","chicago":"Sauer, Michael, Tomasz Paciorek, Eva Benková, and Jiří Friml. “Immunocytochemical Techniques for Whole Mount in Situ Protein Localization in Plants.” <i>Nature Protocols</i>. Nature Publishing Group, 2006. <a href=\"https://doi.org/10.1038/nprot.2006.15\">https://doi.org/10.1038/nprot.2006.15</a>.","ama":"Sauer M, Paciorek T, Benková E, Friml J. Immunocytochemical techniques for whole mount in situ protein localization in plants. <i>Nature Protocols</i>. 2006;1(1):98-103. doi:<a href=\"https://doi.org/10.1038/nprot.2006.15\">10.1038/nprot.2006.15</a>"},"volume":1,"_id":"3015","page":"98 - 103","date_created":"2018-12-11T12:00:52Z","pmid":1,"external_id":{"pmid":["17406218"]},"issue":"1","intvolume":"         1","language":[{"iso":"eng"}],"doi":"10.1038/nprot.2006.15"},{"doi":"10.1038/nprot.2006.16","language":[{"iso":"eng"}],"intvolume":"         1","issue":"1","external_id":{"pmid":["17406219"]},"pmid":1,"date_created":"2018-12-11T12:00:52Z","page":"104 - 107","_id":"3013","volume":1,"citation":{"chicago":"Paciorek, Tomasz, Michael Sauer, Jozef Balla, Justyna Wiśniewska, and Jiří Friml. “Immunocytochemical Technique for Protein Localization in Sections of Plant Tissues.” <i>Nature Protocols</i>. Nature Publishing Group, 2006. <a href=\"https://doi.org/10.1038/nprot.2006.16\">https://doi.org/10.1038/nprot.2006.16</a>.","ama":"Paciorek T, Sauer M, Balla J, Wiśniewska J, Friml J. Immunocytochemical technique for protein localization in sections of plant tissues. <i>Nature Protocols</i>. 2006;1(1):104-107. doi:<a href=\"https://doi.org/10.1038/nprot.2006.16\">10.1038/nprot.2006.16</a>","apa":"Paciorek, T., Sauer, M., Balla, J., Wiśniewska, J., &#38; Friml, J. (2006). Immunocytochemical technique for protein localization in sections of plant tissues. <i>Nature Protocols</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nprot.2006.16\">https://doi.org/10.1038/nprot.2006.16</a>","ista":"Paciorek T, Sauer M, Balla J, Wiśniewska J, Friml J. 2006. Immunocytochemical technique for protein localization in sections of plant tissues. Nature Protocols. 1(1), 104–107.","short":"T. Paciorek, M. Sauer, J. Balla, J. Wiśniewska, J. Friml, Nature Protocols 1 (2006) 104–107.","mla":"Paciorek, Tomasz, et al. “Immunocytochemical Technique for Protein Localization in Sections of Plant Tissues.” <i>Nature Protocols</i>, vol. 1, no. 1, Nature Publishing Group, 2006, pp. 104–07, doi:<a href=\"https://doi.org/10.1038/nprot.2006.16\">10.1038/nprot.2006.16</a>.","ieee":"T. Paciorek, M. Sauer, J. Balla, J. Wiśniewska, and J. Friml, “Immunocytochemical technique for protein localization in sections of plant tissues,” <i>Nature Protocols</i>, vol. 1, no. 1. Nature Publishing Group, pp. 104–107, 2006."},"publication":"Nature Protocols","date_updated":"2026-09-02T13:18:47Z","OA_type":"closed access","title":"Immunocytochemical technique for protein localization in sections of plant tissues","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","status":"public","date_published":"2006-06-01T00:00:00Z","publication_status":"published","publisher":"Nature Publishing Group","article_processing_charge":"No","year":"2006","abstract":[{"text":"There is a growing demand for methods that allow rapid and reliable in situ localization of proteins in plant cells. The immunocytochemistry protocol presented here can be used routinely to observe protein localization patterns in tissue sections of various plant species. This protocol is especially suitable for plant species with more-complex tissue architecture (such as maize, Zea mays), which makes it difficult to use an easier whole-mount procedure for protein localization. To facilitate the antibody-antigen reaction, it is necessary to include a wax-embedding and tissue-sectioning step. The protocol consists of the following procedures: chemical fixation of tissue, dehydration, wax embedding, sectioning, dewaxing, rehydration, blocking and antibody incubation. The detailed protocol, recommended controls and troubleshooting are presented here, along with examples of applications.","lang":"eng"}],"month":"06","fulldoi":"https://doi.org/10.1038/nprot.2006.16","author":[{"first_name":"Tomasz","full_name":"Paciorek, Tomasz","last_name":"Paciorek"},{"first_name":"Michael","last_name":"Sauer","full_name":"Sauer, Michael"},{"full_name":"Balla, Jozef","last_name":"Balla","first_name":"Jozef"},{"first_name":"Justyna","full_name":"Wiśniewska, Justyna","last_name":"Wiśniewska"},{"full_name":"Friml, Jirí","last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"article_type":"original","oa_version":"None","publication_identifier":{"eissn":["1750-2799"],"issn":["1754-2189"]},"publist_id":"3689","day":"01","extern":"1"},{"type":"journal_article","publication_status":"published","status":"public","date_published":"2006-08-01T00:00:00Z","abstract":[{"lang":"eng","text":"Plant biology is currently confronted with an overflow of expression profile data provided by high-throughput microarray transcription analyses. However, the tissue and cellular resolution of these techniques is limited. Thus, it is still necessary to examine the expression pattern of selected candidate genes at a cellular level. Here we present an in situ mRNA hybridization method that is routinely used in the analysis of gene expression patterns. The protocol is optimized for mRNA localizations in sectioned tissue of Arabidopsis seedlings including embryos, roots, hypocotyls, young primary leaves and flowers. The detailed protocol, recommended controls and troubleshooting are presented along with examples of application. The total time for the process is 10 days."}],"year":"2006","article_processing_charge":"No","publisher":"Nature Publishing Group","month":"08","fulldoi":"https://doi.org/10.1038/nprot.2006.226","article_type":"original","author":[{"full_name":"Brewer, Philip","last_name":"Brewer","first_name":"Philip"},{"first_name":"Marcus","full_name":"Heisler, Marcus","last_name":"Heisler"},{"first_name":"Jan","full_name":"Hejátko, Jan","last_name":"Hejátko"},{"first_name":"Jirí","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jirí"},{"last_name":"Benková","full_name":"Benková, Eva","first_name":"Eva","orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"}],"publication_identifier":{"issn":["1754-2189"],"eissn":["1750-2799"]},"oa_version":"None","extern":"1","day":"01","publist_id":"3687","language":[{"iso":"eng"}],"doi":"10.1038/nprot.2006.226","intvolume":"         1","pmid":1,"external_id":{"pmid":["17406436"]},"issue":"3","date_created":"2018-12-11T12:00:52Z","_id":"3014","volume":1,"page":"1462 - 1467","publication":"Nature Protocols","citation":{"mla":"Brewer, Philip, et al. “In Situ Hybridization for MRNA Detection in Arabidopsis Tissue Sections.” <i>Nature Protocols</i>, vol. 1, no. 3, Nature Publishing Group, 2006, pp. 1462–67, doi:<a href=\"https://doi.org/10.1038/nprot.2006.226\">10.1038/nprot.2006.226</a>.","ieee":"P. Brewer, M. Heisler, J. Hejátko, J. Friml, and E. Benková, “In situ hybridization for mRNA detection in Arabidopsis tissue sections,” <i>Nature Protocols</i>, vol. 1, no. 3. Nature Publishing Group, pp. 1462–1467, 2006.","ista":"Brewer P, Heisler M, Hejátko J, Friml J, Benková E. 2006. In situ hybridization for mRNA detection in Arabidopsis tissue sections. Nature Protocols. 1(3), 1462–1467.","short":"P. Brewer, M. Heisler, J. Hejátko, J. Friml, E. Benková, Nature Protocols 1 (2006) 1462–1467.","apa":"Brewer, P., Heisler, M., Hejátko, J., Friml, J., &#38; Benková, E. (2006). In situ hybridization for mRNA detection in Arabidopsis tissue sections. <i>Nature Protocols</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nprot.2006.226\">https://doi.org/10.1038/nprot.2006.226</a>","chicago":"Brewer, Philip, Marcus Heisler, Jan Hejátko, Jiří Friml, and Eva Benková. “In Situ Hybridization for MRNA Detection in Arabidopsis Tissue Sections.” <i>Nature Protocols</i>. Nature Publishing Group, 2006. <a href=\"https://doi.org/10.1038/nprot.2006.226\">https://doi.org/10.1038/nprot.2006.226</a>.","ama":"Brewer P, Heisler M, Hejátko J, Friml J, Benková E. In situ hybridization for mRNA detection in Arabidopsis tissue sections. <i>Nature Protocols</i>. 2006;1(3):1462-1467. doi:<a href=\"https://doi.org/10.1038/nprot.2006.226\">10.1038/nprot.2006.226</a>"},"title":"In situ hybridization for mRNA detection in Arabidopsis tissue sections","OA_type":"closed access","date_updated":"2026-09-02T13:15:08Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"day":"14","extern":"1","publist_id":"3543","publication_identifier":{"issn":["1081-0706"],"eissn":["1530-8995"]},"oa_version":"None","article_type":"original","author":[{"last_name":"Kunwar","full_name":"Kunwar, Prabhat","first_name":"Prabhat"},{"first_name":"Daria E","orcid":"0000-0001-8323-8353","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","full_name":"Siekhaus, Daria E","last_name":"Siekhaus"},{"first_name":"Ruth","full_name":"Lehmann, Ruth","last_name":"Lehmann"}],"fulldoi":"https://doi.org/10.1146/annurev.cellbio.22.010305.103337","month":"06","abstract":[{"lang":"eng","text":"The basic concepts of the molecular machinery that mediates cell migration have been gleaned from cell culture systems. However, the three-dimensional environment within an organism presents migrating cells with a much greater challenge. They must move between and among other cells while interpreting multiple attractive and repulsive cues to choose their proper path. They must coordinate their cell adhesion with their surroundings and know when to start and stop moving. New insights into the control of these remaining mysteries have emerged from genetic dissection and live imaging of germ cell migration in Drosophila, zebrafish, and mouse embryos. In this review, we first describe germ cell migration in cellular and mechanistic detail in these different model systems. We then compare these systems to highlight the emerging principles. Finally, we contrast the migration of germ cells with that of immune and cancer cells to outline the conserved and different mechanisms."}],"publisher":"Annual Reviews","article_processing_charge":"No","year":"2006","publication_status":"published","status":"public","date_published":"2006-06-14T00:00:00Z","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"In vivo migration A germ cell perspective","OA_type":"closed access","date_updated":"2026-09-02T09:38:49Z","publication":"Annual Review of Cell and Developmental Biology","citation":{"apa":"Kunwar, P., Siekhaus, D. E., &#38; Lehmann, R. (2006). In vivo migration A germ cell perspective. <i>Annual Review of Cell and Developmental Biology</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev.cellbio.22.010305.103337\">https://doi.org/10.1146/annurev.cellbio.22.010305.103337</a>","chicago":"Kunwar, Prabhat, Daria E Siekhaus, and Ruth Lehmann. “In Vivo Migration A Germ Cell Perspective.” <i>Annual Review of Cell and Developmental Biology</i>. Annual Reviews, 2006. <a href=\"https://doi.org/10.1146/annurev.cellbio.22.010305.103337\">https://doi.org/10.1146/annurev.cellbio.22.010305.103337</a>.","ama":"Kunwar P, Siekhaus DE, Lehmann R. In vivo migration A germ cell perspective. <i>Annual Review of Cell and Developmental Biology</i>. 2006;22:237-265. doi:<a href=\"https://doi.org/10.1146/annurev.cellbio.22.010305.103337\">10.1146/annurev.cellbio.22.010305.103337</a>","ieee":"P. Kunwar, D. E. Siekhaus, and R. Lehmann, “In vivo migration A germ cell perspective,” <i>Annual Review of Cell and Developmental Biology</i>, vol. 22. Annual Reviews, pp. 237–265, 2006.","mla":"Kunwar, Prabhat, et al. “In Vivo Migration A Germ Cell Perspective.” <i>Annual Review of Cell and Developmental Biology</i>, vol. 22, Annual Reviews, 2006, pp. 237–65, doi:<a href=\"https://doi.org/10.1146/annurev.cellbio.22.010305.103337\">10.1146/annurev.cellbio.22.010305.103337</a>.","ista":"Kunwar P, Siekhaus DE, Lehmann R. 2006. In vivo migration A germ cell perspective. Annual Review of Cell and Developmental Biology. 22, 237–265.","short":"P. Kunwar, D.E. Siekhaus, R. Lehmann, Annual Review of Cell and Developmental Biology 22 (2006) 237–265."},"volume":22,"_id":"3152","page":"237 - 265","date_created":"2018-12-11T12:01:42Z","external_id":{"pmid":["16774460"]},"pmid":1,"intvolume":"        22","language":[{"iso":"eng"}],"doi":"10.1146/annurev.cellbio.22.010305.103337"}]