---
_id: '3276'
abstract:
- lang: eng
  text: 'We present an algorithm to identify individual neural spikes observed on
    high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers
    of distinct neural units, even when spikes overlap, and accounts for intrinsic
    variability of spikes from each unit. As MEAs grow larger, it is important to
    find spike-identification methods that are scalable, that is, the computational
    cost of spike fitting should scale well with the number of units observed. Our
    algorithm accomplishes this goal, and is fast, because it exploits the spatial
    locality of each unit and the basic biophysics of extracellular signal propagation.
    Human interaction plays a key role in our method; but effort is minimized and
    streamlined via a graphical interface. We illustrate our method on data from guinea
    pig retinal ganglion cells and document its performance on simulated data consisting
    of spikes added to experimentally measured background noise. We present several
    tests demonstrating that the algorithm is highly accurate: it exhibits low error
    rates on fits to synthetic data, low refractory violation rates, good receptive
    field coverage, and consistency across users.'
acknowledgement: |+
  This work was supported by National Science Foundation (NSF) grants IBN-0344678, EF-0928048, National Institutes of Health (NIH) grant RO1 EY08124, NIH training grant T32-07035, and NIH training grant 5T90DA022763-04.

  Michael Berry and Olivier Marre have developed an algorithm similar to, but different from, ours (manuscript in preparation). We thank them for discussions of their work, and specifically thank Olivier Marre for suggesting to us that the most complete subtraction of a spike can be obtained by refitting the spike without a prior.

author:
- first_name: Jason
  full_name: Prentice, Jason S
  last_name: Prentice
- first_name: Jan
  full_name: Homann, Jan
  last_name: Homann
- first_name: Kristina
  full_name: Simmons, Kristina D
  last_name: Simmons
- first_name: Gasper
  full_name: Gasper Tkacik
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Vijay
  full_name: Balasubramanian, Vijay
  last_name: Balasubramanian
- first_name: Philip
  full_name: Nelson, Philip C
  last_name: Nelson
citation:
  ama: Prentice J, Homann J, Simmons K, Tkačik G, Balasubramanian V, Nelson P. Fast,
    scalable, Bayesian spike identification for multi-electrode arrays. <i>PLoS One</i>.
    2011;6(7). doi:<a href="https://doi.org/10.1371/journal.pone.0019884">10.1371/journal.pone.0019884</a>
  apa: Prentice, J., Homann, J., Simmons, K., Tkačik, G., Balasubramanian, V., &#38;
    Nelson, P. (2011). Fast, scalable, Bayesian spike identification for multi-electrode
    arrays. <i>PLoS One</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pone.0019884">https://doi.org/10.1371/journal.pone.0019884</a>
  chicago: Prentice, Jason, Jan Homann, Kristina Simmons, Gašper Tkačik, Vijay Balasubramanian,
    and Philip Nelson. “Fast, Scalable, Bayesian Spike Identification for Multi-Electrode
    Arrays.” <i>PLoS One</i>. Public Library of Science, 2011. <a href="https://doi.org/10.1371/journal.pone.0019884">https://doi.org/10.1371/journal.pone.0019884</a>.
  ieee: J. Prentice, J. Homann, K. Simmons, G. Tkačik, V. Balasubramanian, and P.
    Nelson, “Fast, scalable, Bayesian spike identification for multi-electrode arrays,”
    <i>PLoS One</i>, vol. 6, no. 7. Public Library of Science, 2011.
  ista: Prentice J, Homann J, Simmons K, Tkačik G, Balasubramanian V, Nelson P. 2011.
    Fast, scalable, Bayesian spike identification for multi-electrode arrays. PLoS
    One. 6(7).
  mla: Prentice, Jason, et al. “Fast, Scalable, Bayesian Spike Identification for
    Multi-Electrode Arrays.” <i>PLoS One</i>, vol. 6, no. 7, Public Library of Science,
    2011, doi:<a href="https://doi.org/10.1371/journal.pone.0019884">10.1371/journal.pone.0019884</a>.
  short: J. Prentice, J. Homann, K. Simmons, G. Tkačik, V. Balasubramanian, P. Nelson,
    PLoS One 6 (2011).
date_created: 2018-12-11T12:02:24Z
date_published: 2011-07-20T00:00:00Z
date_updated: 2021-01-12T07:42:19Z
day: '20'
doi: 10.1371/journal.pone.0019884
extern: 1
file:
- access_level: open_access
  checksum: 654464e99683b55a699734213d5356f1
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:38Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '4894'
  file_name: IST-2015-381-v1+1_journal.pone.0019884.pdf
  file_size: 885464
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
fulldoi: https://doi.org/10.1371/journal.pone.0019884
intvolume: '         6'
issue: '7'
license: https://creativecommons.org/licenses/by/4.0/
month: '07'
oa: 1
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '3370'
pubrep_id: '381'
quality_controlled: 0
status: public
title: Fast, scalable, Bayesian spike identification for multi-electrode arrays
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
volume: 6
year: '2011'
...
...
---
_id: '3278'
abstract:
- lang: eng
  text: |-
    Despite much research on the socially parasitic large blue butterflies (genus Maculinea) in the past 40 years, their relationship to their closest relatives, Phengaris, is controversial and the relationships among the remaining genera in the Glaucopsyche section are largely unresolved. The evolutionary history of this butterfly section is particularly important to understand the evolution of life history diversity con- nected to food-plant and host-ant associations in the larval stage. In the present study, we use a combi- nation of four nuclear and two mitochondrial genes to reconstruct the phylogeny of the Glaucopsyche section, and in particular, to study the relationships among and within the Phengaris–Maculinea species.
    We find a clear pattern between the clades recovered in the Glaucopsyche section phylogeny and their food-plant associations, with only the Phengaris–Maculinea clade utilising more than one plant family. Maculinea is, for the first time, recovered with strong support as a monophyletic group nested within Phengaris, with the closest relative being the rare genus Caerulea. The genus Glaucopsyche is polyphyletic, including the genera Sinia and Iolana. Interestingly, we find evidence for additional potential cryptic spe- cies within the highly endangered Maculinea, which has long been suspected from morphological, ecolog- ical and molecular studies.
author:
- first_name: Roger
  full_name: Vila, Roger
  last_name: Vila
- first_name: Naomi
  full_name: Pierce, Naomi E
  last_name: Pierce
- first_name: David
  full_name: Nash, David R
  last_name: Nash
- first_name: Line V
  full_name: Line Ugelvig
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
citation:
  ama: 'Vila R, Pierce N, Nash D, Ugelvig LV. A phylogenetic revision of the Glaucopsyche
    section (Lepidoptera: Lycaenidae), with special focus on the Phengaris-Maculinea
    clade. <i>Molecular Phylogenetics and Evolution</i>. 2011;61(1):237-243. doi:<a
    href="https://doi.org/10.1016/j.ympev.2011.05.016">10.1016/j.ympev.2011.05.016</a>'
  apa: 'Vila, R., Pierce, N., Nash, D., &#38; Ugelvig, L. V. (2011). A phylogenetic
    revision of the Glaucopsyche section (Lepidoptera: Lycaenidae), with special focus
    on the Phengaris-Maculinea clade. <i>Molecular Phylogenetics and Evolution</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.ympev.2011.05.016">https://doi.org/10.1016/j.ympev.2011.05.016</a>'
  chicago: 'Vila, Roger, Naomi Pierce, David Nash, and Line V Ugelvig. “A Phylogenetic
    Revision of the Glaucopsyche Section (Lepidoptera: Lycaenidae), with Special Focus
    on the Phengaris-Maculinea Clade.” <i>Molecular Phylogenetics and Evolution</i>.
    Elsevier, 2011. <a href="https://doi.org/10.1016/j.ympev.2011.05.016">https://doi.org/10.1016/j.ympev.2011.05.016</a>.'
  ieee: 'R. Vila, N. Pierce, D. Nash, and L. V. Ugelvig, “A phylogenetic revision
    of the Glaucopsyche section (Lepidoptera: Lycaenidae), with special focus on the
    Phengaris-Maculinea clade,” <i>Molecular Phylogenetics and Evolution</i>, vol.
    61, no. 1. Elsevier, pp. 237–243, 2011.'
  ista: 'Vila R, Pierce N, Nash D, Ugelvig LV. 2011. A phylogenetic revision of the
    Glaucopsyche section (Lepidoptera: Lycaenidae), with special focus on the Phengaris-Maculinea
    clade. Molecular Phylogenetics and Evolution. 61(1), 237–243.'
  mla: 'Vila, Roger, et al. “A Phylogenetic Revision of the Glaucopsyche Section (Lepidoptera:
    Lycaenidae), with Special Focus on the Phengaris-Maculinea Clade.” <i>Molecular
    Phylogenetics and Evolution</i>, vol. 61, no. 1, Elsevier, 2011, pp. 237–43, doi:<a
    href="https://doi.org/10.1016/j.ympev.2011.05.016">10.1016/j.ympev.2011.05.016</a>.'
  short: R. Vila, N. Pierce, D. Nash, L.V. Ugelvig, Molecular Phylogenetics and Evolution
    61 (2011) 237–243.
date_created: 2018-12-11T12:02:25Z
date_published: 2011-10-01T00:00:00Z
date_updated: 2021-01-12T07:42:20Z
day: '01'
doi: 10.1016/j.ympev.2011.05.016
extern: 1
fulldoi: https://doi.org/10.1016/j.ympev.2011.05.016
intvolume: '        61'
issue: '1'
month: '10'
page: 237 - 243
publication: Molecular Phylogenetics and Evolution
publication_status: published
publisher: Elsevier
publist_id: '3368'
quality_controlled: 0
status: public
title: 'A phylogenetic revision of the Glaucopsyche section (Lepidoptera: Lycaenidae),
  with special focus on the Phengaris-Maculinea clade'
type: journal_article
volume: 61
year: '2011'
...
---
_id: '3285'
abstract:
- lang: eng
  text: Resolving the dynamical interplay of proteins and lipids in the live-cell
    plasma membrane represents a central goal in current cell biology. Superresolution
    concepts have introduced a means of capturing spatial heterogeneity at a nanoscopic
    length scale. Similar concepts for detecting dynamical transitions (superresolution
    chronoscopy) are still lacking. Here, we show that recently introduced spot-variation
    fluorescence correlation spectroscopy allows for sensing transient confinement
    times of membrane constituents at dramatically improved resolution. Using standard
    diffraction-limited optics, spot-variation fluorescence correlation spectroscopy
    captures signatures of single retardation events far below the transit time of
    the tracer through the focal spot. We provide an analytical description of special
    cases of transient binding of a tracer to pointlike traps, or association of a
    tracer with nanodomains. The influence of trap mobility and the underlying binding
    kinetics are quantified. Experimental approaches are suggested that allow for
    gaining quantitative mechanistic insights into the interaction processes of membrane
    constituents.
acknowledgement: Y 250-B03/Austrian Science Fund FWF/Austria
author:
- first_name: Verena
  full_name: Ruprecht, Verena
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Stefan
  full_name: Wieser, Stefan
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
- first_name: Didier
  full_name: Marguet, Didier
  last_name: Marguet
- first_name: Gerhard
  full_name: Schuetz, Gerhard
  last_name: Schuetz
citation:
  ama: Ruprecht V, Wieser S, Marguet D, Schuetz G. Spot variation fluorescence correlation
    spectroscopy allows for superresolution chronoscopy of confinement times in membranes.
    <i>Biophysical Journal</i>. 2011;100(11):2839-2845. doi:<a href="https://doi.org/10.1016/j.bpj.2011.04.035">10.1016/j.bpj.2011.04.035</a>
  apa: Ruprecht, V., Wieser, S., Marguet, D., &#38; Schuetz, G. (2011). Spot variation
    fluorescence correlation spectroscopy allows for superresolution chronoscopy of
    confinement times in membranes. <i>Biophysical Journal</i>. Biophysical Society.
    <a href="https://doi.org/10.1016/j.bpj.2011.04.035">https://doi.org/10.1016/j.bpj.2011.04.035</a>
  chicago: Ruprecht, Verena, Stefan Wieser, Didier Marguet, and Gerhard Schuetz. “Spot
    Variation Fluorescence Correlation Spectroscopy Allows for Superresolution Chronoscopy
    of Confinement Times in Membranes.” <i>Biophysical Journal</i>. Biophysical Society,
    2011. <a href="https://doi.org/10.1016/j.bpj.2011.04.035">https://doi.org/10.1016/j.bpj.2011.04.035</a>.
  ieee: V. Ruprecht, S. Wieser, D. Marguet, and G. Schuetz, “Spot variation fluorescence
    correlation spectroscopy allows for superresolution chronoscopy of confinement
    times in membranes,” <i>Biophysical Journal</i>, vol. 100, no. 11. Biophysical
    Society, pp. 2839–2845, 2011.
  ista: Ruprecht V, Wieser S, Marguet D, Schuetz G. 2011. Spot variation fluorescence
    correlation spectroscopy allows for superresolution chronoscopy of confinement
    times in membranes. Biophysical Journal. 100(11), 2839–2845.
  mla: Ruprecht, Verena, et al. “Spot Variation Fluorescence Correlation Spectroscopy
    Allows for Superresolution Chronoscopy of Confinement Times in Membranes.” <i>Biophysical
    Journal</i>, vol. 100, no. 11, Biophysical Society, 2011, pp. 2839–45, doi:<a
    href="https://doi.org/10.1016/j.bpj.2011.04.035">10.1016/j.bpj.2011.04.035</a>.
  short: V. Ruprecht, S. Wieser, D. Marguet, G. Schuetz, Biophysical Journal 100 (2011)
    2839–2845.
date_created: 2018-12-11T12:02:27Z
date_published: 2011-06-08T00:00:00Z
date_updated: 2021-01-12T07:42:23Z
day: '08'
doi: 10.1016/j.bpj.2011.04.035
extern: '1'
fulldoi: https://doi.org/10.1016/j.bpj.2011.04.035
intvolume: '       100'
issue: '11'
language:
- iso: eng
month: '06'
oa_version: None
page: 2839 - 2845
publication: Biophysical Journal
publication_status: published
publisher: Biophysical Society
publist_id: '3360'
status: public
title: Spot variation fluorescence correlation spectroscopy allows for superresolution
  chronoscopy of confinement times in membranes
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 100
year: '2011'
...
---
_id: '3286'
abstract:
- lang: eng
  text: Cationic antimicrobial peptides (CAMPs) selectively target bacterial membranes
    by electrostatic interactions with negatively charged lipids. It turned out that
    for inhibition of microbial growth a high CAMP membrane concentration is required,
    which can be realized by the incorporation of hydrophobic groups within the peptide.
    Increasing hydrophobicity, however, reduces the CAMP selectivity for bacterial
    over eukaryotic host membranes, thereby causing the risk of detrimental side-effects.
    In this study we addressed how cationic amphipathic peptides—in particular a CAMP
    with Lysine–Leucine–Lysine repeats (termed KLK)—affect the localization and dynamics
    of molecules in eukaryotic membranes. We found KLK to selectively inhibit the
    endocytosis of a subgroup of membrane proteins and lipids by electrostatically
    interacting with negatively charged sialic acid moieties. Ultrastructural characterization
    revealed the formation of membrane invaginations representing fission or fusion
    intermediates, in which the sialylated proteins and lipids were immobilized. Experiments
    on structurally different cationic amphipathic peptides (KLK, 6-MO-LF11-322 and
    NK14-2) indicated a cooperation of electrostatic and hydrophobic forces that selectively
    arrest sialylated membrane constituents.
acknowledgement: "This work was funded by the GEN-AU project of the Austrian Research
  Promotion Agency, the Austrian Science Fund (FWF; project Y250-B03) and Intercell
  AG.\nWe thank the following colleagues for providing plasmids and cells: Daniel
  Legler (University of Konstanz, Switzerland), Jennifer Lippincott-Schwartz (NIH,
  Bethesda, USA), Hannes Stockinger (Medical University Vienna, Austria), Katharina
  Strub (University of Geneva, Switzerland), Lawrence Rajendran (ETH Zurich, Switzerland),
  Eileen M. Lafer (UTHSC San Antonio, Texas, USA), Mark McNiven (Mayo Clinic, Minnesota,
  USA), John Silvius (McGill University, Montreal, Canada), Christoph Romanin (JKU
  Linz, Austria), Herbert Stangl (Medical University Vienna, Austria) and Anton van
  der Merwe (Oxford University, Oxford, UK). We thank Harald Kotisch (MFPL, Vienna)
  for excellent technical assistance in the processing of samples for electron microscopy
  and Sergio Grinstein (Hospital for Sick Children Research Institute, Toronto) for
  fruitful discussions. "
author:
- first_name: Julian
  full_name: Weghuber, Julian
  last_name: Weghuber
- first_name: Michael
  full_name: Aichinger, Michael C.
  last_name: Aichinger
- first_name: Mario
  full_name: Brameshuber, Mario
  last_name: Brameshuber
- first_name: Stefan
  full_name: Stefan Wieser
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
- first_name: Verena
  full_name: Verena Ruprecht
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Birgit
  full_name: Plochberger, Birgit
  last_name: Plochberger
- first_name: Josef
  full_name: Madl, Josef
  last_name: Madl
- first_name: Andreas
  full_name: Horner, Andreas
  last_name: Horner
- first_name: Siegfried
  full_name: Reipert, Siegfried
  last_name: Reipert
- first_name: Karl
  full_name: Lohner, Karl
  last_name: Lohner
- first_name: Tamas
  full_name: Henics, Tamas
  last_name: Henics
- first_name: Gerhard
  full_name: Schuetz, Gerhard J
  last_name: Schuetz
citation:
  ama: Weghuber J, Aichinger M, Brameshuber M, et al. Cationic amphipathic peptides
    accumulate sialylated proteins and lipids in the plasma membrane of eukaryotic
    host cells. <i>Biochimica et Biophysica Acta (BBA) - Biomembranes</i>. 2011;1808(10):2581-2590.
    doi:<a href="https://doi.org/10.1016/j.bbamem.2011.06.007">10.1016/j.bbamem.2011.06.007</a>
  apa: Weghuber, J., Aichinger, M., Brameshuber, M., Wieser, S., Ruprecht, V., Plochberger,
    B., … Schuetz, G. (2011). Cationic amphipathic peptides accumulate sialylated
    proteins and lipids in the plasma membrane of eukaryotic host cells. <i>Biochimica
    et Biophysica Acta (BBA) - Biomembranes</i>. Elsevier. <a href="https://doi.org/10.1016/j.bbamem.2011.06.007">https://doi.org/10.1016/j.bbamem.2011.06.007</a>
  chicago: Weghuber, Julian, Michael Aichinger, Mario Brameshuber, Stefan Wieser,
    Verena Ruprecht, Birgit Plochberger, Josef Madl, et al. “Cationic Amphipathic
    Peptides Accumulate Sialylated Proteins and Lipids in the Plasma Membrane of Eukaryotic
    Host Cells.” <i>Biochimica et Biophysica Acta (BBA) - Biomembranes</i>. Elsevier,
    2011. <a href="https://doi.org/10.1016/j.bbamem.2011.06.007">https://doi.org/10.1016/j.bbamem.2011.06.007</a>.
  ieee: J. Weghuber <i>et al.</i>, “Cationic amphipathic peptides accumulate sialylated
    proteins and lipids in the plasma membrane of eukaryotic host cells,” <i>Biochimica
    et Biophysica Acta (BBA) - Biomembranes</i>, vol. 1808, no. 10. Elsevier, pp.
    2581–2590, 2011.
  ista: Weghuber J, Aichinger M, Brameshuber M, Wieser S, Ruprecht V, Plochberger
    B, Madl J, Horner A, Reipert S, Lohner K, Henics T, Schuetz G. 2011. Cationic
    amphipathic peptides accumulate sialylated proteins and lipids in the plasma membrane
    of eukaryotic host cells. Biochimica et Biophysica Acta (BBA) - Biomembranes.
    1808(10), 2581–2590.
  mla: Weghuber, Julian, et al. “Cationic Amphipathic Peptides Accumulate Sialylated
    Proteins and Lipids in the Plasma Membrane of Eukaryotic Host Cells.” <i>Biochimica
    et Biophysica Acta (BBA) - Biomembranes</i>, vol. 1808, no. 10, Elsevier, 2011,
    pp. 2581–90, doi:<a href="https://doi.org/10.1016/j.bbamem.2011.06.007">10.1016/j.bbamem.2011.06.007</a>.
  short: J. Weghuber, M. Aichinger, M. Brameshuber, S. Wieser, V. Ruprecht, B. Plochberger,
    J. Madl, A. Horner, S. Reipert, K. Lohner, T. Henics, G. Schuetz, Biochimica et
    Biophysica Acta (BBA) - Biomembranes 1808 (2011) 2581–2590.
date_created: 2018-12-11T12:02:28Z
date_published: 2011-10-01T00:00:00Z
date_updated: 2021-01-12T07:42:24Z
day: '01'
doi: 10.1016/j.bbamem.2011.06.007
extern: 1
fulldoi: https://doi.org/10.1016/j.bbamem.2011.06.007
intvolume: '      1808'
issue: '10'
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '10'
page: 2581 - 2590
publication: Biochimica et Biophysica Acta (BBA) - Biomembranes
publication_status: published
publisher: Elsevier
publist_id: '3359'
quality_controlled: 0
status: public
title: Cationic amphipathic peptides accumulate sialylated proteins and lipids in
  the plasma membrane of eukaryotic host cells
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
volume: 1808
year: '2011'
...
---
_id: '3287'
abstract:
- lang: eng
  text: 'Diffusing membrane constituents are constantly exposed to a variety of forces
    that influence their stochastic path. Single molecule experiments allow for resolving
    trajectories at extremely high spatial and temporal accuracy, thereby offering
    insights into en route interactions of the tracer. In this review we discuss approaches
    to derive information about the underlying processes, based on single molecule
    tracking experiments. In particular, we focus on a new versatile way to analyze
    single molecule diffusion in the absence of a full analytical treatment. The method
    is based on comprehensive comparison of an experimental data set against the hypothetical
    outcome of multiple experiments performed on the computer. Since Monte Carlo simulations
    can be easily and rapidly performed even on state-of-the-art PCs, our method provides
    a simple way for testing various - even complicated - diffusion models. We describe
    the new method in detail, and show the applicability on two specific examples:
    firstly, kinetic rate constants can be derived for the transient interaction of
    mobile membrane proteins; secondly, residence time and corral size can be extracted
    for confined diffusion.'
article_processing_charge: No
author:
- first_name: Verena
  full_name: Ruprecht, Verena
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Markus
  full_name: Axmann, Markus
  last_name: Axmann
- first_name: Stefan
  full_name: Wieser, Stefan
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
- first_name: Gerhard
  full_name: Schuetz, Gerhard
  last_name: Schuetz
citation:
  ama: Ruprecht V, Axmann M, Wieser S, Schuetz G. What can we learn from single molecule
    trajectories? <i>Current Protein &#38; Peptide Science</i>. 2011;12(8):714-724.
    doi:<a href="https://doi.org/10.2174/138920311798841753">10.2174/138920311798841753</a>
  apa: Ruprecht, V., Axmann, M., Wieser, S., &#38; Schuetz, G. (2011). What can we
    learn from single molecule trajectories? <i>Current Protein &#38; Peptide Science</i>.
    Bentham Science Publishers. <a href="https://doi.org/10.2174/138920311798841753">https://doi.org/10.2174/138920311798841753</a>
  chicago: Ruprecht, Verena, Markus Axmann, Stefan Wieser, and Gerhard Schuetz. “What
    Can We Learn from Single Molecule Trajectories?” <i>Current Protein &#38; Peptide
    Science</i>. Bentham Science Publishers, 2011. <a href="https://doi.org/10.2174/138920311798841753">https://doi.org/10.2174/138920311798841753</a>.
  ieee: V. Ruprecht, M. Axmann, S. Wieser, and G. Schuetz, “What can we learn from
    single molecule trajectories?,” <i>Current Protein &#38; Peptide Science</i>,
    vol. 12, no. 8. Bentham Science Publishers, pp. 714–724, 2011.
  ista: Ruprecht V, Axmann M, Wieser S, Schuetz G. 2011. What can we learn from single
    molecule trajectories? Current Protein &#38; Peptide Science. 12(8), 714–724.
  mla: Ruprecht, Verena, et al. “What Can We Learn from Single Molecule Trajectories?”
    <i>Current Protein &#38; Peptide Science</i>, vol. 12, no. 8, Bentham Science
    Publishers, 2011, pp. 714–24, doi:<a href="https://doi.org/10.2174/138920311798841753">10.2174/138920311798841753</a>.
  short: V. Ruprecht, M. Axmann, S. Wieser, G. Schuetz, Current Protein &#38; Peptide
    Science 12 (2011) 714–724.
date_created: 2018-12-11T12:02:28Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2025-09-30T09:21:31Z
day: '01'
department:
- _id: CaHe
- _id: MiSi
doi: 10.2174/138920311798841753
external_id:
  isi:
  - '000299672600005'
fulldoi: https://doi.org/10.2174/138920311798841753
intvolume: '        12'
isi: 1
issue: '8'
language:
- iso: eng
month: '12'
oa_version: None
page: 714 - 724
publication: Current Protein & Peptide Science
publication_status: published
publisher: Bentham Science Publishers
publist_id: '3358'
quality_controlled: '1'
scopus_import: '1'
status: public
title: What can we learn from single molecule trajectories?
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 12
year: '2011'
...
---
_id: '3288'
abstract:
- lang: eng
  text: 'The zonula adherens (ZA) of epithelial cells is a site of cell-cell adhesion
    where cellular forces are exerted and resisted. Increasing evidence indicates
    that E-cadherin adhesion molecules at the ZA serve to sense force applied on the
    junctions and coordinate cytoskeletal responses to those forces. Efforts to understand
    the role that cadherins play in mechanotransduction have been limited by the lack
    of assays to measure the impact of forces on the ZA. In this study we used 4D
    imaging of GFP-tagged E-cadherin to analyse the movement of the ZA. Junctions
    in confluent epithelial monolayers displayed prominent movements oriented orthogonal
    (perpendicular) to the ZA itself. Two components were identified in these movements:
    a relatively slow unidirectional (translational) component that could be readily
    fitted by least-squares regression analysis, upon which were superimposed more
    rapid oscillatory movements. Myosin IIB was a dominant factor responsible for
    driving the unilateral translational movements. In contrast, frequency spectrum
    analysis revealed that depletion of Myosin IIA increased the power of the oscillatory
    movements. This implies that Myosin IIA may serve to dampen oscillatory movements
    of the ZA. This extends our recent analysis of Myosin II at the ZA to demonstrate
    that Myosin IIA and Myosin IIB make distinct contributions to junctional movement
    at the ZA.'
acknowledgement: his work was funded by the National Health and Medical Research Council
  (NHMRC) of Australia. M.S. was an Erwin Schroedinger postdoctoral fellow of the
  Austrian Science Fund (FWF), S.K.W. is supported by a UQ International Research
  Tuition Award and Research Scholarship, S.M .by an ANZ Trustees PhD Scholarship.
  A.S.Y. is a Research Fellow of the NHMRC. Confocal imaging was performed at the
  Australian Cancer Research Foundation (ACRF) Cancer Biology Imaging Centre at the
  Institute for Molecular Bioscience, established with the generous support of the
  ACRF.
article_processing_charge: No
author:
- first_name: Michael
  full_name: Smutny, Michael
  id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
  last_name: Smutny
  orcid: 0000-0002-5920-9090
- first_name: Selwin
  full_name: Wu, Selwin
  last_name: Wu
- first_name: Guillermo
  full_name: Gomez, Guillermo
  last_name: Gomez
- first_name: Sabine
  full_name: Mangold, Sabine
  last_name: Mangold
- first_name: Alpha
  full_name: Yap, Alpha
  last_name: Yap
- first_name: Nicholas
  full_name: Hamilton, Nicholas
  last_name: Hamilton
citation:
  ama: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. Multicomponent analysis
    of junctional movements regulated by Myosin II isoforms at the epithelial zonula
    adherens. <i>PLoS One</i>. 2011;6(7). doi:<a href="https://doi.org/10.1371/journal.pone.0022458">10.1371/journal.pone.0022458</a>
  apa: Smutny, M., Wu, S., Gomez, G., Mangold, S., Yap, A., &#38; Hamilton, N. (2011).
    Multicomponent analysis of junctional movements regulated by Myosin II isoforms
    at the epithelial zonula adherens. <i>PLoS One</i>. Public Library of Science.
    <a href="https://doi.org/10.1371/journal.pone.0022458">https://doi.org/10.1371/journal.pone.0022458</a>
  chicago: Smutny, Michael, Selwin Wu, Guillermo Gomez, Sabine Mangold, Alpha Yap,
    and Nicholas Hamilton. “Multicomponent Analysis of Junctional Movements Regulated
    by Myosin II Isoforms at the Epithelial Zonula Adherens.” <i>PLoS One</i>. Public
    Library of Science, 2011. <a href="https://doi.org/10.1371/journal.pone.0022458">https://doi.org/10.1371/journal.pone.0022458</a>.
  ieee: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, and N. Hamilton, “Multicomponent
    analysis of junctional movements regulated by Myosin II isoforms at the epithelial
    zonula adherens,” <i>PLoS One</i>, vol. 6, no. 7. Public Library of Science, 2011.
  ista: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. 2011. Multicomponent
    analysis of junctional movements regulated by Myosin II isoforms at the epithelial
    zonula adherens. PLoS One. 6(7).
  mla: Smutny, Michael, et al. “Multicomponent Analysis of Junctional Movements Regulated
    by Myosin II Isoforms at the Epithelial Zonula Adherens.” <i>PLoS One</i>, vol.
    6, no. 7, Public Library of Science, 2011, doi:<a href="https://doi.org/10.1371/journal.pone.0022458">10.1371/journal.pone.0022458</a>.
  short: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, N. Hamilton, PLoS One 6 (2011).
date_created: 2018-12-11T12:02:28Z
date_published: 2011-07-22T00:00:00Z
date_updated: 2025-09-30T09:26:01Z
day: '22'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1371/journal.pone.0022458
external_id:
  isi:
  - '000293097300049'
file:
- access_level: open_access
  checksum: 57a5eb11dd05241c48c44f492b3ec3ac
  content_type: application/pdf
  creator: dernst
  date_created: 2019-05-10T10:51:43Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '6399'
  file_name: 2011_PLOS_Smutny.PDF
  file_size: 1984567
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
fulldoi: https://doi.org/10.1371/journal.pone.0022458
has_accepted_license: '1'
intvolume: '         6'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '3357'
quality_controlled: '1'
status: public
title: Multicomponent analysis of junctional movements regulated by Myosin II isoforms
  at the epithelial zonula adherens
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2011'
...
---
_id: '3290'
abstract:
- lang: eng
  text: 'Analysis of genomic data requires an efficient way to calculate likelihoods
    across very large numbers of loci. We describe a general method for finding the
    distribution of genealogies: we allow migration between demes, splitting of demes
    [as in the isolation-with-migration (IM) model], and recombination between linked
    loci. These processes are described by a set of linear recursions for the generating
    function of branch lengths. Under the infinite-sites model, the probability of
    any configuration of mutations can be found by differentiating this generating
    function. Such calculations are feasible for small numbers of sampled genomes:
    as an example, we show how the generating function can be derived explicitly for
    three genes under the two-deme IM model. This derivation is done automatically,
    using Mathematica. Given data from a large number of unlinked and nonrecombining
    blocks of sequence, these results can be used to find maximum-likelihood estimates
    of model parameters by tabulating the probabilities of all relevant mutational
    configurations and then multiplying across loci. The feasibility of the method
    is demonstrated by applying it to simulated data and to a data set previously
    analyzed by Wang and Hey (2010) consisting of 26,141 loci sampled from Drosophila
    simulans and D. melanogaster. Our results suggest that such likelihood calculations
    are scalable to genomic data as long as the numbers of sampled individuals and
    mutations per sequence block are small.'
article_processing_charge: No
author:
- first_name: Konrad
  full_name: Lohse, Konrad
  last_name: Lohse
- first_name: Richard
  full_name: Harrison, Richard
  last_name: Harrison
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Lohse K, Harrison R, Barton NH. A general method for calculating likelihoods
    under the coalescent process. <i>Genetics</i>. 2011;189(3):977-987. doi:<a href="https://doi.org/10.1534/genetics.111.129569">10.1534/genetics.111.129569</a>
  apa: Lohse, K., Harrison, R., &#38; Barton, N. H. (2011). A general method for calculating
    likelihoods under the coalescent process. <i>Genetics</i>. Genetics Society of
    America. <a href="https://doi.org/10.1534/genetics.111.129569">https://doi.org/10.1534/genetics.111.129569</a>
  chicago: Lohse, Konrad, Richard Harrison, and Nicholas H Barton. “A General Method
    for Calculating Likelihoods under the Coalescent Process.” <i>Genetics</i>. Genetics
    Society of America, 2011. <a href="https://doi.org/10.1534/genetics.111.129569">https://doi.org/10.1534/genetics.111.129569</a>.
  ieee: K. Lohse, R. Harrison, and N. H. Barton, “A general method for calculating
    likelihoods under the coalescent process,” <i>Genetics</i>, vol. 189, no. 3. Genetics
    Society of America, pp. 977–987, 2011.
  ista: Lohse K, Harrison R, Barton NH. 2011. A general method for calculating likelihoods
    under the coalescent process. Genetics. 189(3), 977–987.
  mla: Lohse, Konrad, et al. “A General Method for Calculating Likelihoods under the
    Coalescent Process.” <i>Genetics</i>, vol. 189, no. 3, Genetics Society of America,
    2011, pp. 977–87, doi:<a href="https://doi.org/10.1534/genetics.111.129569">10.1534/genetics.111.129569</a>.
  short: K. Lohse, R. Harrison, N.H. Barton, Genetics 189 (2011) 977–987.
date_created: 2018-12-11T12:02:29Z
date_published: 2011-11-01T00:00:00Z
date_updated: 2025-09-30T09:21:06Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.111.129569
ec_funded: 1
external_id:
  isi:
  - '000297020800022'
fulldoi: https://doi.org/10.1534/genetics.111.129569
intvolume: '       189'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213358/
month: '11'
oa: 1
oa_version: Submitted Version
page: 977 - 987
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '3355'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A general method for calculating likelihoods under the coalescent process
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 189
year: '2011'
...
---
_id: '3297'
abstract:
- lang: eng
  text: "Animating detailed liquid surfaces has always been a challenge for computer
    graphics researchers and visual effects artists. Over the past few years, researchers
    in this field have focused on mesh-based surface tracking to synthesize extremely
    detailed liquid surfaces as efficiently as possible. This course provides a solid
    understanding of the steps required to create a fluid simulator with a mesh-based
    liquid surface.\r\n\r\nThe course begins with an overview of several existing
    liquid-surface-tracking techniques and the pros and cons of each method. Then
    it explains how to embed a triangle mesh into a finite-difference-based fluid
    simulator and describes several methods for allowing the liquid surface to merge
    together or break apart. The final section showcases the benefits and further
    applications of a mesh-based liquid surface, highlighting state-of-the-art methods
    for tracking colors and textures, maintaining liquid volume, preserving small
    surface features, and simulating realistic surface-tension waves."
article_number: '8'
author:
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Matthias
  full_name: Müller Fischer, Matthias
  last_name: Müller Fischer
- first_name: Tyson
  full_name: Brochu, Tyson
  last_name: Brochu
citation:
  ama: 'Wojtan C, Müller Fischer M, Brochu T. Liquid simulation with mesh-based surface
    tracking. In: ACM; 2011. doi:<a href="https://doi.org/10.1145/2037636.2037644">10.1145/2037636.2037644</a>'
  apa: 'Wojtan, C., Müller Fischer, M., &#38; Brochu, T. (2011). Liquid simulation
    with mesh-based surface tracking. Presented at the SIGGRAPH: Special Interest
    Group on Computer Graphics and Interactive Techniques, Vancouver, BC, Canada:
    ACM. <a href="https://doi.org/10.1145/2037636.2037644">https://doi.org/10.1145/2037636.2037644</a>'
  chicago: Wojtan, Chris, Matthias Müller Fischer, and Tyson Brochu. “Liquid Simulation
    with Mesh-Based Surface Tracking.” ACM, 2011. <a href="https://doi.org/10.1145/2037636.2037644">https://doi.org/10.1145/2037636.2037644</a>.
  ieee: 'C. Wojtan, M. Müller Fischer, and T. Brochu, “Liquid simulation with mesh-based
    surface tracking,” presented at the SIGGRAPH: Special Interest Group on Computer
    Graphics and Interactive Techniques, Vancouver, BC, Canada, 2011.'
  ista: 'Wojtan C, Müller Fischer M, Brochu T. 2011. Liquid simulation with mesh-based
    surface tracking. SIGGRAPH: Special Interest Group on Computer Graphics and Interactive
    Techniques, 8.'
  mla: Wojtan, Chris, et al. <i>Liquid Simulation with Mesh-Based Surface Tracking</i>.
    8, ACM, 2011, doi:<a href="https://doi.org/10.1145/2037636.2037644">10.1145/2037636.2037644</a>.
  short: C. Wojtan, M. Müller Fischer, T. Brochu, in:, ACM, 2011.
conference:
  end_date: 2011-08-11
  location: Vancouver, BC, Canada
  name: 'SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques'
  start_date: 2011-08-07
corr_author: '1'
date_created: 2018-12-11T12:02:31Z
date_published: 2011-08-07T00:00:00Z
date_updated: 2024-10-09T20:54:35Z
day: '07'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2037636.2037644
file:
- access_level: open_access
  checksum: 8d508ad7c82f50978acbaa4170ee0a75
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:34Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '5018'
  file_name: IST-2016-599-v1+1_meshyFluidsCourseSIGGRAPH2011.pdf
  file_size: 34672096
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
fulldoi: https://doi.org/10.1145/2037636.2037644
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication_status: published
publisher: ACM
publist_id: '3344'
pubrep_id: '599'
quality_controlled: '1'
scopus_import: 1
status: public
title: Liquid simulation with mesh-based surface tracking
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3298'
abstract:
- lang: eng
  text: We present a new algorithm for enforcing incompressibility for Smoothed Particle
    Hydrodynamics (SPH) by preserving uniform density across the domain. We propose
    a hybrid method that uses a Poisson solve on a coarse grid to enforce a divergence
    free velocity ﬁeld, followed by a local density correction of the particles. This
    avoids typical grid artifacts and maintains the Lagrangian nature of SPH by directly
    transferring pressures onto particles. Our method can be easily integrated with
    existing SPH techniques such as the incompressible PCISPH method as well as weakly
    compressible SPH by adding an additional force term. We show that this hybrid
    method accelerates convergence towards uniform density and permits a signiﬁcantly
    larger time step compared to earlier approaches while producing similar results.
    We demonstrate our approach in a variety of scenarios with signiﬁcant pressure
    gradients such as splashing liquids.
author:
- first_name: Karthik
  full_name: Raveendran, Karthik
  last_name: Raveendran
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Greg
  full_name: Turk, Greg
  last_name: Turk
citation:
  ama: 'Raveendran K, Wojtan C, Turk G. Hybrid smoothed particle hydrodynamics. In:
    Spencer S, ed. ACM; 2011:33-42. doi:<a href="https://doi.org/10.1145/2019406.2019411">10.1145/2019406.2019411</a>'
  apa: 'Raveendran, K., Wojtan, C., &#38; Turk, G. (2011). Hybrid smoothed particle
    hydrodynamics. In S. Spencer (Ed.) (pp. 33–42). Presented at the SCA: ACM SIGGRAPH/Eurographics
    Symposium on Computer animation, Vancouver, Canada: ACM. <a href="https://doi.org/10.1145/2019406.2019411">https://doi.org/10.1145/2019406.2019411</a>'
  chicago: Raveendran, Karthik, Chris Wojtan, and Greg Turk. “Hybrid Smoothed Particle
    Hydrodynamics.” edited by Stephen Spencer, 33–42. ACM, 2011. <a href="https://doi.org/10.1145/2019406.2019411">https://doi.org/10.1145/2019406.2019411</a>.
  ieee: 'K. Raveendran, C. Wojtan, and G. Turk, “Hybrid smoothed particle hydrodynamics,”
    presented at the SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation,
    Vancouver, Canada, 2011, pp. 33–42.'
  ista: 'Raveendran K, Wojtan C, Turk G. 2011. Hybrid smoothed particle hydrodynamics.
    SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation, 33–42.'
  mla: Raveendran, Karthik, et al. <i>Hybrid Smoothed Particle Hydrodynamics</i>.
    Edited by Stephen Spencer, ACM, 2011, pp. 33–42, doi:<a href="https://doi.org/10.1145/2019406.2019411">10.1145/2019406.2019411</a>.
  short: K. Raveendran, C. Wojtan, G. Turk, in:, S. Spencer (Ed.), ACM, 2011, pp.
    33–42.
conference:
  end_date: 2011-08-07
  location: Vancouver, Canada
  name: 'SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation'
  start_date: 2011-08-05
date_created: 2018-12-11T12:02:32Z
date_published: 2011-08-05T00:00:00Z
date_updated: 2023-02-23T11:21:05Z
day: '05'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2019406.2019411
editor:
- first_name: Stephen
  full_name: Spencer, Stephen
  last_name: Spencer
file:
- access_level: open_access
  checksum: 6579d27709946e0eefbfa60a456b4913
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:09:44Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '4769'
  file_name: IST-2016-598-v1+1_HybridSPH_Preprint.pdf
  file_size: 2536216
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
fulldoi: https://doi.org/10.1145/2019406.2019411
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
page: 33 - 42
publication_status: published
publisher: ACM
publist_id: '3343'
pubrep_id: '598'
quality_controlled: '1'
scopus_import: 1
status: public
title: Hybrid smoothed particle hydrodynamics
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3299'
abstract:
- lang: eng
  text: 'We introduce propagation models, a formalism designed to support general
    and efficient data structures for the transient analysis of biochemical reaction
    networks. We give two use cases for propagation abstract data types: the uniformization
    method and numerical integration. We also sketch an implementation of a propagation
    abstract data type, which uses abstraction to approximate states.'
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Maria
  full_name: Mateescu, Maria
  last_name: Mateescu
citation:
  ama: 'Henzinger TA, Mateescu M. Propagation models for computing biochemical reaction
    networks. In: Springer; 2011:1-3. doi:<a href="https://doi.org/10.1145/2037509.2037510">10.1145/2037509.2037510</a>'
  apa: 'Henzinger, T. A., &#38; Mateescu, M. (2011). Propagation models for computing
    biochemical reaction networks (pp. 1–3). Presented at the CMSB: Computational
    Methods in Systems Biology, Paris, France: Springer. <a href="https://doi.org/10.1145/2037509.2037510">https://doi.org/10.1145/2037509.2037510</a>'
  chicago: Henzinger, Thomas A, and Maria Mateescu. “Propagation Models for Computing
    Biochemical Reaction Networks,” 1–3. Springer, 2011. <a href="https://doi.org/10.1145/2037509.2037510">https://doi.org/10.1145/2037509.2037510</a>.
  ieee: 'T. A. Henzinger and M. Mateescu, “Propagation models for computing biochemical
    reaction networks,” presented at the CMSB: Computational Methods in Systems Biology,
    Paris, France, 2011, pp. 1–3.'
  ista: 'Henzinger TA, Mateescu M. 2011. Propagation models for computing biochemical
    reaction networks. CMSB: Computational Methods in Systems Biology, 1–3.'
  mla: Henzinger, Thomas A., and Maria Mateescu. <i>Propagation Models for Computing
    Biochemical Reaction Networks</i>. Springer, 2011, pp. 1–3, doi:<a href="https://doi.org/10.1145/2037509.2037510">10.1145/2037509.2037510</a>.
  short: T.A. Henzinger, M. Mateescu, in:, Springer, 2011, pp. 1–3.
conference:
  end_date: 2011-09-23
  location: Paris, France
  name: 'CMSB: Computational Methods in Systems Biology'
  start_date: 2011-09-21
corr_author: '1'
date_created: 2018-12-11T12:02:32Z
date_published: 2011-09-21T00:00:00Z
date_updated: 2024-10-09T20:54:34Z
day: '21'
ddc:
- '000'
- '004'
department:
- _id: ToHe
doi: 10.1145/2037509.2037510
file:
- access_level: open_access
  checksum: 7f5c65509db1a9fb049abedd9663ed06
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:07:50Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '4649'
  file_name: IST-2012-92-v1+1_Propagation_models_for_computing_biochemical_reaction_networks.pdf
  file_size: 255780
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
fulldoi: https://doi.org/10.1145/2037509.2037510
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 1 - 3
publication_status: published
publisher: Springer
publist_id: '3341'
pubrep_id: '92'
quality_controlled: '1'
scopus_import: 1
status: public
title: Propagation models for computing biochemical reaction networks
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3301'
abstract:
- lang: eng
  text: The chemical master equation is a differential equation describing the time
    evolution of the probability distribution over the possible “states” of a biochemical
    system. The solution of this equation is of interest within the systems biology
    field ever since the importance of the molec- ular noise has been acknowledged.
    Unfortunately, most of the systems do not have analytical solutions, and numerical
    solutions suffer from the course of dimensionality and therefore need to be approximated.
    Here, we introduce the concept of tail approximation, which retrieves an approximation
    of the probabilities in the tail of a distribution from the total probability
    of the tail and its conditional expectation. This approximation method can then
    be used to numerically compute the solution of the chemical master equation on
    a subset of the state space, thus fighting the explosion of the state space, for
    which this problem is renowned.
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Maria
  full_name: Mateescu, Maria
  last_name: Mateescu
citation:
  ama: 'Henzinger TA, Mateescu M. Tail approximation for the chemical master equation.
    In: Tampere International Center for Signal Processing; 2011.'
  apa: 'Henzinger, T. A., &#38; Mateescu, M. (2011). Tail approximation for the chemical
    master equation. Presented at the WCSB: Workshop on Computational Systems Biology
    (TICSP), Tampere International Center for Signal Processing.'
  chicago: Henzinger, Thomas A, and Maria Mateescu. “Tail Approximation for the Chemical
    Master Equation.” Tampere International Center for Signal Processing, 2011.
  ieee: 'T. A. Henzinger and M. Mateescu, “Tail approximation for the chemical master
    equation,” presented at the WCSB: Workshop on Computational Systems Biology (TICSP),
    2011.'
  ista: 'Henzinger TA, Mateescu M. 2011. Tail approximation for the chemical master
    equation. WCSB: Workshop on Computational Systems Biology (TICSP).'
  mla: Henzinger, Thomas A., and Maria Mateescu. <i>Tail Approximation for the Chemical
    Master Equation</i>. Tampere International Center for Signal Processing, 2011.
  short: T.A. Henzinger, M. Mateescu, in:, Tampere International Center for Signal
    Processing, 2011.
conference:
  name: 'WCSB: Workshop on Computational Systems Biology (TICSP)'
corr_author: '1'
date_created: 2018-12-11T12:02:33Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2024-10-09T20:54:34Z
day: '01'
ddc:
- '005'
- '570'
department:
- _id: ToHe
file:
- access_level: open_access
  checksum: aa4d7a832a5419e6c0090650ebff2b9a
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:18:12Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '5331'
  file_name: IST-2012-91-v1+1_Tail_approximation_for_the_chemical_master_equation.pdf
  file_size: 240820
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
publication_status: published
publisher: Tampere International Center for Signal Processing
publist_id: '3339'
pubrep_id: '91'
quality_controlled: '1'
status: public
title: Tail approximation for the chemical master equation
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3311'
abstract:
- lang: eng
  text: Alpha shapes have been conceived in 1981 as an attempt to define the shape
    of a finite set of point in the plane. Since then, connections to diverse areas
    in the sciences and engineering have developed, including to pattern recognition,
    digital shape sampling and processing, and structural molecular biology. This
    survey begins with a historical account and discusses geometric, algorithmic,
    topological, and combinatorial aspects of alpha shapes in this sequence.
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: 'Edelsbrunner H. Alpha shapes - a survey. In: van de Weygaert R, Vegter G,
    Ritzerveld J, Icke V, eds. <i>Tessellations in the Sciences: Virtues, Techniques
    and Applications of Geometric Tilings</i>. Springer.'
  apa: 'Edelsbrunner, H. (n.d.). Alpha shapes - a survey. In R. van de Weygaert, G.
    Vegter, J. Ritzerveld, &#38; V. Icke (Eds.), <i>Tessellations in the Sciences:
    Virtues, Techniques and Applications of Geometric Tilings</i>. Springer.'
  chicago: 'Edelsbrunner, Herbert. “Alpha Shapes - a Survey.” In <i>Tessellations
    in the Sciences: Virtues, Techniques and Applications of Geometric Tilings</i>,
    edited by R van de Weygaert, G Vegter, J Ritzerveld, and V Icke. Springer, n.d.'
  ieee: 'H. Edelsbrunner, “Alpha shapes - a survey,” in <i>Tessellations in the Sciences:
    Virtues, Techniques and Applications of Geometric Tilings</i>, R. van de Weygaert,
    G. Vegter, J. Ritzerveld, and V. Icke, Eds. Springer.'
  ista: 'Edelsbrunner H.Alpha shapes - a survey. In: Tessellations in the Sciences:
    Virtues, Techniques and Applications of Geometric Tilings. .'
  mla: 'Edelsbrunner, Herbert. “Alpha Shapes - a Survey.” <i>Tessellations in the
    Sciences: Virtues, Techniques and Applications of Geometric Tilings</i>, edited
    by R van de Weygaert et al., Springer.'
  short: 'H. Edelsbrunner, in:, R. van de Weygaert, G. Vegter, J. Ritzerveld, V. Icke
    (Eds.), Tessellations in the Sciences: Virtues, Techniques and Applications of
    Geometric Tilings, Springer, n.d.'
corr_author: '1'
date_created: 2018-12-11T12:02:36Z
date_published: 2011-12-31T00:00:00Z
date_updated: 2024-10-09T20:54:33Z
day: '31'
ddc:
- '510'
department:
- _id: HeEd
editor:
- first_name: R
  full_name: van de Weygaert, R
  last_name: van de Weygaert
- first_name: G
  full_name: Vegter, G
  last_name: Vegter
- first_name: J
  full_name: Ritzerveld, J
  last_name: Ritzerveld
- first_name: V
  full_name: Icke, V
  last_name: Icke
file:
- access_level: open_access
  checksum: a592ea438351e7280eea993a7713ab8f
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-24T07:55:05Z
  date_updated: 2022-05-24T07:55:05Z
  file_id: '11408'
  file_name: 2010_AlphaShapes.pdf
  file_size: 475254
  relation: main_file
  success: 1
file_date_updated: 2022-05-24T07:55:05Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
publication: 'Tessellations in the Sciences: Virtues, Techniques and Applications
  of Geometric Tilings'
publication_status: inpress
publisher: Springer
publist_id: '3329'
quality_controlled: '1'
status: public
title: Alpha shapes - a survey
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3312'
abstract:
- lang: eng
  text: We study the 3D reconstruction of plant roots from multiple 2D images. To
    meet the challenge caused by the delicate nature of thin branches, we make three
    innovations to cope with the sensitivity to image quality and calibration. First,
    we model the background as a harmonic function to improve the segmentation of
    the root in each 2D image. Second, we develop the concept of the regularized visual
    hull which reduces the effect of jittering and refraction by ensuring consistency
    with one 2D image. Third, we guarantee connectedness through adjustments to the
    3D reconstruction that minimize global error. Our software is part of a biological
    phenotype/genotype study of agricultural root systems. It has been tested on more
    than 40 plant roots and results are promising in terms of reconstruction quality
    and efficiency.
acknowledgement: This research is supported by the National Science Foundation (NSF)
  under grant DBI-0820624.
article_number: '6126475'
article_processing_charge: No
author:
- first_name: Ying
  full_name: Zheng, Ying
  last_name: Zheng
- first_name: Steve
  full_name: Gu, Steve
  last_name: Gu
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Carlo
  full_name: Tomasi, Carlo
  last_name: Tomasi
- first_name: Philip
  full_name: Benfey, Philip
  last_name: Benfey
citation:
  ama: Zheng Y, Gu S, Edelsbrunner H, Tomasi C, Benfey P. <i>Detailed Reconstruction
    of 3D Plant Root Shape</i>. IEEE; 2011. doi:<a href="https://doi.org/10.1109/ICCV.2011.6126475">10.1109/ICCV.2011.6126475</a>
  apa: 'Zheng, Y., Gu, S., Edelsbrunner, H., Tomasi, C., &#38; Benfey, P. (2011).
    <i>Detailed reconstruction of 3D plant root shape</i>. <i>Proceedings of the IEEE
    International Conference on Computer Vision</i>. Barcelona, Spain: IEEE. <a href="https://doi.org/10.1109/ICCV.2011.6126475">https://doi.org/10.1109/ICCV.2011.6126475</a>'
  chicago: Zheng, Ying, Steve Gu, Herbert Edelsbrunner, Carlo Tomasi, and Philip Benfey.
    <i>Detailed Reconstruction of 3D Plant Root Shape</i>. <i>Proceedings of the IEEE
    International Conference on Computer Vision</i>. IEEE, 2011. <a href="https://doi.org/10.1109/ICCV.2011.6126475">https://doi.org/10.1109/ICCV.2011.6126475</a>.
  ieee: Y. Zheng, S. Gu, H. Edelsbrunner, C. Tomasi, and P. Benfey, <i>Detailed reconstruction
    of 3D plant root shape</i>. IEEE, 2011.
  ista: Zheng Y, Gu S, Edelsbrunner H, Tomasi C, Benfey P. 2011. Detailed reconstruction
    of 3D plant root shape, IEEE,p.
  mla: Zheng, Ying, et al. “Detailed Reconstruction of 3D Plant Root Shape.” <i>Proceedings
    of the IEEE International Conference on Computer Vision</i>, 6126475, IEEE, 2011,
    doi:<a href="https://doi.org/10.1109/ICCV.2011.6126475">10.1109/ICCV.2011.6126475</a>.
  short: Y. Zheng, S. Gu, H. Edelsbrunner, C. Tomasi, P. Benfey, Detailed Reconstruction
    of 3D Plant Root Shape, IEEE, 2011.
conference:
  end_date: 2011-11-13
  location: Barcelona, Spain
  name: 'ICCV: International Conference on Computer Vision'
  start_date: 2011-11-06
date_created: 2018-12-11T12:02:36Z
date_published: 2011-12-31T00:00:00Z
date_updated: 2024-10-21T06:03:02Z
day: '31'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1109/ICCV.2011.6126475
file:
- access_level: open_access
  checksum: 30a33564b7b45a7ee31610898267fd0e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:09:04Z
  date_updated: 2020-07-14T12:46:07Z
  file_id: '4727'
  file_name: IST-2016-541-v1+1_2011-P-07-RootReconstruction.pdf
  file_size: 5622728
  relation: main_file
file_date_updated: 2020-07-14T12:46:07Z
fulldoi: https://doi.org/10.1109/ICCV.2011.6126475
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
publication: Proceedings of the IEEE International Conference on Computer Vision
publication_status: published
publisher: IEEE
publist_id: '3328'
pubrep_id: '541'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Detailed reconstruction of 3D plant root shape
type: conference_poster
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3313'
abstract:
- lang: eng
  text: Interpreting an image as a function on a compact sub- set of the Euclidean
    plane, we get its scale-space by diffu- sion, spreading the image over the entire
    plane. This gener- ates a 1-parameter family of functions alternatively defined
    as convolutions with a progressively wider Gaussian ker- nel. We prove that the
    corresponding 1-parameter family of persistence diagrams have norms that go rapidly
    to zero as time goes to infinity. This result rationalizes experimental observations
    about scale-space. We hope this will lead to targeted improvements of related
    computer vision methods.
article_number: '6126271'
author:
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: 'Chen C, Edelsbrunner H. Diffusion runs low on persistence fast. In: <i>Proceedings
    of the IEEE International Conference on Computer Vision</i>. IEEE; 2011. doi:<a
    href="https://doi.org/10.1109/ICCV.2011.6126271">10.1109/ICCV.2011.6126271</a>'
  apa: 'Chen, C., &#38; Edelsbrunner, H. (2011). Diffusion runs low on persistence
    fast. In <i>Proceedings of the IEEE International Conference on Computer Vision</i>.
    Barcelona, Spain: IEEE. <a href="https://doi.org/10.1109/ICCV.2011.6126271">https://doi.org/10.1109/ICCV.2011.6126271</a>'
  chicago: Chen, Chao, and Herbert Edelsbrunner. “Diffusion Runs Low on Persistence
    Fast.” In <i>Proceedings of the IEEE International Conference on Computer Vision</i>.
    IEEE, 2011. <a href="https://doi.org/10.1109/ICCV.2011.6126271">https://doi.org/10.1109/ICCV.2011.6126271</a>.
  ieee: C. Chen and H. Edelsbrunner, “Diffusion runs low on persistence fast,” in
    <i>Proceedings of the IEEE International Conference on Computer Vision</i>, Barcelona,
    Spain, 2011.
  ista: 'Chen C, Edelsbrunner H. 2011. Diffusion runs low on persistence fast. Proceedings
    of the IEEE International Conference on Computer Vision. ICCV: International Conference
    on Computer Vision, 6126271.'
  mla: Chen, Chao, and Herbert Edelsbrunner. “Diffusion Runs Low on Persistence Fast.”
    <i>Proceedings of the IEEE International Conference on Computer Vision</i>, 6126271,
    IEEE, 2011, doi:<a href="https://doi.org/10.1109/ICCV.2011.6126271">10.1109/ICCV.2011.6126271</a>.
  short: C. Chen, H. Edelsbrunner, in:, Proceedings of the IEEE International Conference
    on Computer Vision, IEEE, 2011.
conference:
  end_date: 2011-11-13
  location: Barcelona, Spain
  name: 'ICCV: International Conference on Computer Vision'
  start_date: 2011-11-06
corr_author: '1'
date_created: 2018-12-11T12:02:37Z
date_published: 2011-11-06T00:00:00Z
date_updated: 2024-10-09T20:54:33Z
day: '06'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1109/ICCV.2011.6126271
file:
- access_level: open_access
  checksum: 6984684081ba123808b344f9f2e64a8f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:28Z
  date_updated: 2020-07-14T12:46:07Z
  file_id: '5282'
  file_name: IST-2016-540-v1+1_2011-P-08-RunEmpty.pdf
  file_size: 614050
  relation: main_file
file_date_updated: 2020-07-14T12:46:07Z
fulldoi: https://doi.org/10.1109/ICCV.2011.6126271
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
publication: Proceedings of the IEEE International Conference on Computer Vision
publication_status: published
publisher: IEEE
publist_id: '3327'
pubrep_id: '540'
quality_controlled: '1'
scopus_import: 1
status: public
title: Diffusion runs low on persistence fast
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3316'
abstract:
- lang: eng
  text: In addition to being correct, a system should be robust, that is, it should
    behave reasonably even after receiving unexpected inputs. In this paper, we summarize
    two formal notions of robustness that we have introduced previously for reactive
    systems. One of the notions is based on assigning costs for failures on a user-provided
    notion of incorrect transitions in a specification. Here, we define a system to
    be robust if a finite number of incorrect inputs does not lead to an infinite
    number of incorrect outputs. We also give a more refined notion of robustness
    that aims to minimize the ratio of output failures to input failures. The second
    notion is aimed at liveness. In contrast to the previous notion, it has no concept
    of recovery from an error. Instead, it compares the ratio of the number of liveness
    constraints that the system violates to the number of liveness constraints that
    the environment violates.
article_processing_charge: No
author:
- first_name: Roderick
  full_name: Bloem, Roderick
  last_name: Bloem
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Karin
  full_name: Greimel, Karin
  last_name: Greimel
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Barbara
  full_name: Jobstmann, Barbara
  last_name: Jobstmann
citation:
  ama: 'Bloem R, Chatterjee K, Greimel K, Henzinger TA, Jobstmann B. Specification-centered
    robustness. In: <i>6th IEEE International Symposium on Industrial and Embedded
    Systems</i>. IEEE; 2011:176-185. doi:<a href="https://doi.org/10.1109/SIES.2011.5953660">10.1109/SIES.2011.5953660</a>'
  apa: 'Bloem, R., Chatterjee, K., Greimel, K., Henzinger, T. A., &#38; Jobstmann,
    B. (2011). Specification-centered robustness. In <i>6th IEEE International Symposium
    on Industrial and Embedded Systems</i> (pp. 176–185). Vasteras, Sweden: IEEE.
    <a href="https://doi.org/10.1109/SIES.2011.5953660">https://doi.org/10.1109/SIES.2011.5953660</a>'
  chicago: Bloem, Roderick, Krishnendu Chatterjee, Karin Greimel, Thomas A Henzinger,
    and Barbara Jobstmann. “Specification-Centered Robustness.” In <i>6th IEEE International
    Symposium on Industrial and Embedded Systems</i>, 176–85. IEEE, 2011. <a href="https://doi.org/10.1109/SIES.2011.5953660">https://doi.org/10.1109/SIES.2011.5953660</a>.
  ieee: R. Bloem, K. Chatterjee, K. Greimel, T. A. Henzinger, and B. Jobstmann, “Specification-centered
    robustness,” in <i>6th IEEE International Symposium on Industrial and Embedded
    Systems</i>, Vasteras, Sweden, 2011, pp. 176–185.
  ista: 'Bloem R, Chatterjee K, Greimel K, Henzinger TA, Jobstmann B. 2011. Specification-centered
    robustness. 6th IEEE International Symposium on Industrial and Embedded Systems.
    SIES: International Symposium on Industrial Embedded Systems, 176–185.'
  mla: Bloem, Roderick, et al. “Specification-Centered Robustness.” <i>6th IEEE International
    Symposium on Industrial and Embedded Systems</i>, IEEE, 2011, pp. 176–85, doi:<a
    href="https://doi.org/10.1109/SIES.2011.5953660">10.1109/SIES.2011.5953660</a>.
  short: R. Bloem, K. Chatterjee, K. Greimel, T.A. Henzinger, B. Jobstmann, in:, 6th
    IEEE International Symposium on Industrial and Embedded Systems, IEEE, 2011, pp.
    176–185.
conference:
  end_date: 2011-06-17
  location: Vasteras, Sweden
  name: 'SIES: International Symposium on Industrial Embedded Systems'
  start_date: 2011-06-15
date_created: 2018-12-11T12:02:38Z
date_published: 2011-07-14T00:00:00Z
date_updated: 2026-06-18T18:43:15Z
day: '14'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1109/SIES.2011.5953660
ec_funded: 1
fulldoi: https://doi.org/10.1109/SIES.2011.5953660
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://openlib.tugraz.at/download.php?id=5cb57c8a49344&location=browse
month: '07'
oa: 1
oa_version: Published Version
page: 176 - 185
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25F2ACDE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Rigorous Systems Engineering
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '214373'
  name: Design for Embedded Systems
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication: 6th IEEE International Symposium on Industrial and Embedded Systems
publication_status: published
publisher: IEEE
publist_id: '3323'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Specification-centered robustness
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3318'
abstract:
- lang: eng
  text: Parvalbumin is thought to act in a manner similar to EGTA, but how a slow
    Ca2+ buffer affects nanodomain-coupling regimes at GABAergic synapses is unclear.
    Direct measurements of parvalbumin concentration and paired recordings in rodent
    hippocampus and cerebellum revealed that parvalbumin affects synaptic dynamics
    only when expressed at high levels. Modeling suggests that, in high concentrations,
    parvalbumin may exert BAPTA-like effects, modulating nanodomain coupling via competition
    with local saturation of endogenous fixed buffers.
article_processing_charge: No
author:
- first_name: Emmanuel
  full_name: Eggermann, Emmanuel
  last_name: Eggermann
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Eggermann E, Jonas PM. How the “slow” Ca(2+) buffer parvalbumin affects transmitter
    release in nanodomain coupling regimes at GABAergic synapses. <i>Nature Neuroscience</i>.
    2011;15:20-22. doi:<a href="https://doi.org/10.1038/nn.3002">10.1038/nn.3002</a>
  apa: Eggermann, E., &#38; Jonas, P. M. (2011). How the “slow” Ca(2+) buffer parvalbumin
    affects transmitter release in nanodomain coupling regimes at GABAergic synapses.
    <i>Nature Neuroscience</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nn.3002">https://doi.org/10.1038/nn.3002</a>
  chicago: Eggermann, Emmanuel, and Peter M Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin
    Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.”
    <i>Nature Neuroscience</i>. Nature Publishing Group, 2011. <a href="https://doi.org/10.1038/nn.3002">https://doi.org/10.1038/nn.3002</a>.
  ieee: E. Eggermann and P. M. Jonas, “How the ‘slow’ Ca(2+) buffer parvalbumin affects
    transmitter release in nanodomain coupling regimes at GABAergic synapses,” <i>Nature
    Neuroscience</i>, vol. 15. Nature Publishing Group, pp. 20–22, 2011.
  ista: Eggermann E, Jonas PM. 2011. How the “slow” Ca(2+) buffer parvalbumin affects
    transmitter release in nanodomain coupling regimes at GABAergic synapses. Nature
    Neuroscience. 15, 20–22.
  mla: Eggermann, Emmanuel, and Peter M. Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin
    Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.”
    <i>Nature Neuroscience</i>, vol. 15, Nature Publishing Group, 2011, pp. 20–22,
    doi:<a href="https://doi.org/10.1038/nn.3002">10.1038/nn.3002</a>.
  short: E. Eggermann, P.M. Jonas, Nature Neuroscience 15 (2011) 20–22.
corr_author: '1'
date_created: 2018-12-11T12:02:38Z
date_published: 2011-12-04T00:00:00Z
date_updated: 2025-09-30T09:20:05Z
day: '04'
department:
- _id: PeJo
doi: 10.1038/nn.3002
external_id:
  isi:
  - '000298414400008'
fulldoi: https://doi.org/10.1038/nn.3002
intvolume: '        15'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631701/
month: '12'
oa: 1
oa_version: Submitted Version
page: 20 - 22
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '3321'
quality_controlled: '1'
scopus_import: '1'
status: public
title: How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain
  coupling regimes at GABAergic synapses
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2011'
...
---
_id: '3319'
abstract:
- lang: eng
  text: We address the problem of metric learning for multi-view data, namely the
    construction of embedding projections from data in different representations into
    a shared feature space, such that the Euclidean distance in this space provides
    a meaningful within-view as well as between-view similarity. Our motivation stems
    from the problem of cross-media retrieval tasks, where the availability of a joint
    Euclidean distance function is a pre-requisite to allow fast, in particular hashing-based,
    nearest neighbor queries. We formulate an objective function that expresses the
    intuitive concept that matching samples are mapped closely together in the output
    space, whereas non-matching samples are pushed apart, no matter in which view
    they are available. The resulting optimization problem is not convex, but it can
    be decomposed explicitly into a convex and a concave part, thereby allowing efficient
    optimization using the convex-concave procedure. Experiments on an image retrieval
    task show that nearest-neighbor based cross-view retrieval is indeed possible,
    and the proposed technique improves the retrieval accuracy over baseline techniques.
article_processing_charge: No
author:
- first_name: Novi
  full_name: Quadrianto, Novi
  last_name: Quadrianto
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Quadrianto N, Lampert C. Learning multi-view neighborhood preserving projections.
    In: ML Research Press; 2011:425-432.'
  apa: 'Quadrianto, N., &#38; Lampert, C. (2011). Learning multi-view neighborhood
    preserving projections (pp. 425–432). Presented at the ICML: International Conference
    on Machine Learning, Bellevue, United States: ML Research Press.'
  chicago: Quadrianto, Novi, and Christoph Lampert. “Learning Multi-View Neighborhood
    Preserving Projections,” 425–32. ML Research Press, 2011.
  ieee: 'N. Quadrianto and C. Lampert, “Learning multi-view neighborhood preserving
    projections,” presented at the ICML: International Conference on Machine Learning,
    Bellevue, United States, 2011, pp. 425–432.'
  ista: 'Quadrianto N, Lampert C. 2011. Learning multi-view neighborhood preserving
    projections. ICML: International Conference on Machine Learning, 425–432.'
  mla: Quadrianto, Novi, and Christoph Lampert. <i>Learning Multi-View Neighborhood
    Preserving Projections</i>. ML Research Press, 2011, pp. 425–32.
  short: N. Quadrianto, C. Lampert, in:, ML Research Press, 2011, pp. 425–432.
conference:
  end_date: 2011-07-02
  location: Bellevue, United States
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2011-06-28
corr_author: '1'
date_created: 2018-12-11T12:02:39Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2024-10-09T20:54:32Z
day: '01'
department:
- _id: ChLa
language:
- iso: eng
month: '01'
oa_version: None
page: 425 - 432
publication_status: published
publisher: ML Research Press
publist_id: '3316'
scopus_import: '1'
status: public
title: Learning multi-view neighborhood preserving projections
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3320'
abstract:
- lang: eng
  text: Powerful statistical models that can be learned efficiently from large amounts
    of data are currently revolutionizing computer vision. These models possess a
    rich internal structure reflecting task-specific relations and constraints. This
    monograph introduces the reader to the most popular classes of structured models
    in computer vision. Our focus is discrete undirected graphical models which we
    cover in detail together with a description of algorithms for both probabilistic
    inference and maximum a posteriori inference. We discuss separately recently successful
    techniques for prediction in general structured models. In the second part of
    this monograph we describe methods for parameter learning where we distinguish
    the classic maximum likelihood based methods from the more recent prediction-based
    parameter learning methods. We highlight developments to enhance current models
    and discuss kernelized models and latent variable models. To make the monograph
    more practical and to provide links to further study we provide examples of successful
    application of many methods in the computer vision literature.
article_processing_charge: No
article_type: original
author:
- first_name: Sebastian
  full_name: Nowozin, Sebastian
  last_name: Nowozin
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: Nowozin S, Lampert C. Structured learning and prediction in computer vision.
    <i>Foundations and Trends in Computer Graphics and Vision</i>. 2011;6(3-4):185-365.
    doi:<a href="https://doi.org/10.1561/0600000033">10.1561/0600000033</a>
  apa: Nowozin, S., &#38; Lampert, C. (2011). Structured learning and prediction in
    computer vision. <i>Foundations and Trends in Computer Graphics and Vision</i>.
    Now Publishers. <a href="https://doi.org/10.1561/0600000033">https://doi.org/10.1561/0600000033</a>
  chicago: Nowozin, Sebastian, and Christoph Lampert. “Structured Learning and Prediction
    in Computer Vision.” <i>Foundations and Trends in Computer Graphics and Vision</i>.
    Now Publishers, 2011. <a href="https://doi.org/10.1561/0600000033">https://doi.org/10.1561/0600000033</a>.
  ieee: S. Nowozin and C. Lampert, “Structured learning and prediction in computer
    vision,” <i>Foundations and Trends in Computer Graphics and Vision</i>, vol. 6,
    no. 3–4. Now Publishers, pp. 185–365, 2011.
  ista: Nowozin S, Lampert C. 2011. Structured learning and prediction in computer
    vision. Foundations and Trends in Computer Graphics and Vision. 6(3–4), 185–365.
  mla: Nowozin, Sebastian, and Christoph Lampert. “Structured Learning and Prediction
    in Computer Vision.” <i>Foundations and Trends in Computer Graphics and Vision</i>,
    vol. 6, no. 3–4, Now Publishers, 2011, pp. 185–365, doi:<a href="https://doi.org/10.1561/0600000033">10.1561/0600000033</a>.
  short: S. Nowozin, C. Lampert, Foundations and Trends in Computer Graphics and Vision
    6 (2011) 185–365.
corr_author: '1'
date_created: 2018-12-11T12:02:39Z
date_published: 2011-05-23T00:00:00Z
date_updated: 2024-10-09T20:54:32Z
day: '23'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.1561/0600000033
file:
- access_level: open_access
  checksum: f1043ef389f1558e2a226bb51568511f
  content_type: application/pdf
  creator: dernst
  date_created: 2020-05-14T14:34:47Z
  date_updated: 2020-07-14T12:46:07Z
  file_id: '7837'
  file_name: 2011_CompGraphicsVision_Nowozin.pdf
  file_size: 3745064
  relation: main_file
file_date_updated: 2020-07-14T12:46:07Z
fulldoi: https://doi.org/10.1561/0600000033
has_accepted_license: '1'
intvolume: '         6'
issue: 3-4
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 185 - 365
publication: Foundations and Trends in Computer Graphics and Vision
publication_status: published
publisher: Now Publishers
publist_id: '3315'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structured learning and prediction in computer vision
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2011'
...
---
_id: '3322'
abstract:
- lang: eng
  text: We study multi-label prediction for structured output spaces, a problem that
    occurs, for example, in object detection in images, secondary structure prediction
    in computational biology, and graph matching with symmetries. Conventional multi-label
    classification techniques are typically not applicable in this situation, because
    they require explicit enumeration of the label space, which is infeasible in case
    of structured outputs. Relying on techniques originally designed for single- label
    structured prediction, in particular structured support vector machines, results
    in reduced prediction accuracy, or leads to infeasible optimization problems.
    In this work we derive a maximum-margin training formulation for multi-label structured
    prediction that remains computationally tractable while achieving high prediction
    accuracy. It also shares most beneficial properties with single-label maximum-margin
    approaches, in particular a formulation as a convex optimization problem, efficient
    working set training, and PAC-Bayesian generalization bounds.
article_processing_charge: No
author:
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: Lampert C. <i>Maximum Margin Multi Label Structured Prediction</i>. Neural
    Information Processing Systems Foundation; 2011.
  apa: 'Lampert, C. (2011). <i>Maximum margin multi label structured prediction</i>.
    <i>NIPS: Neural Information Processing Systems</i>. Neural Information Processing
    Systems Foundation.'
  chicago: 'Lampert, Christoph. <i>Maximum Margin Multi Label Structured Prediction</i>.
    <i>NIPS: Neural Information Processing Systems</i>. Neural Information Processing
    Systems Foundation, 2011.'
  ieee: C. Lampert, <i>Maximum margin multi label structured prediction</i>. Neural
    Information Processing Systems Foundation, 2011.
  ista: Lampert C. 2011. Maximum margin multi label structured prediction, Neural
    Information Processing Systems Foundation,p.
  mla: 'Lampert, Christoph. “Maximum Margin Multi Label Structured Prediction.” <i>NIPS:
    Neural Information Processing Systems</i>, Neural Information Processing Systems
    Foundation, 2011.'
  short: C. Lampert, Maximum Margin Multi Label Structured Prediction, Neural Information
    Processing Systems Foundation, 2011.
date_created: 2018-12-11T12:02:40Z
date_published: 2011-12-13T00:00:00Z
date_updated: 2025-06-03T11:47:47Z
day: '13'
department:
- _id: ChLa
language:
- iso: eng
month: '12'
oa_version: None
publication: 'NIPS: Neural Information Processing Systems'
publication_status: published
publisher: Neural Information Processing Systems Foundation
publist_id: '3313'
related_material:
  record:
  - id: '3163'
    relation: earlier_version
    status: public
status: public
title: Maximum margin multi label structured prediction
type: conference_poster
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3323'
abstract:
- lang: eng
  text: We present a new decidable logic called TREX for expressing constraints about
    imperative tree data structures. In particular, TREX supports a transitive closure
    operator that can express reachability constraints, which often appear in data
    structure invariants. We show that our logic is closed under weakest precondition
    computation, which enables its use for automated software verification. We further
    show that satisfiability of formulas in TREX is decidable in NP. The low complexity
    makes it an attractive alternative to more expensive logics such as monadic second-order
    logic (MSOL) over trees, which have been traditionally used for reasoning about
    tree data structures.
alternative_title:
- 'LNAI '
author:
- first_name: Thomas
  full_name: Wies, Thomas
  id: 447BFB88-F248-11E8-B48F-1D18A9856A87
  last_name: Wies
- first_name: Marco
  full_name: Muñiz, Marco
  last_name: Muñiz
- first_name: Viktor
  full_name: Kuncak, Viktor
  last_name: Kuncak
citation:
  ama: 'Wies T, Muñiz M, Kuncak V. An efficient decision procedure for imperative
    tree data structures. In: Vol 6803. Springer; 2011:476-491. doi:<a href="https://doi.org/10.1007/978-3-642-22438-6_36">10.1007/978-3-642-22438-6_36</a>'
  apa: 'Wies, T., Muñiz, M., &#38; Kuncak, V. (2011). An efficient decision procedure
    for imperative tree data structures (Vol. 6803, pp. 476–491). Presented at the
    CADE 23: Automated Deduction , Wrocław, Poland: Springer. <a href="https://doi.org/10.1007/978-3-642-22438-6_36">https://doi.org/10.1007/978-3-642-22438-6_36</a>'
  chicago: Wies, Thomas, Marco Muñiz, and Viktor Kuncak. “An Efficient Decision Procedure
    for Imperative Tree Data Structures,” 6803:476–91. Springer, 2011. <a href="https://doi.org/10.1007/978-3-642-22438-6_36">https://doi.org/10.1007/978-3-642-22438-6_36</a>.
  ieee: 'T. Wies, M. Muñiz, and V. Kuncak, “An efficient decision procedure for imperative
    tree data structures,” presented at the CADE 23: Automated Deduction , Wrocław,
    Poland, 2011, vol. 6803, pp. 476–491.'
  ista: 'Wies T, Muñiz M, Kuncak V. 2011. An efficient decision procedure for imperative
    tree data structures. CADE 23: Automated Deduction , LNAI , vol. 6803, 476–491.'
  mla: Wies, Thomas, et al. <i>An Efficient Decision Procedure for Imperative Tree
    Data Structures</i>. Vol. 6803, Springer, 2011, pp. 476–91, doi:<a href="https://doi.org/10.1007/978-3-642-22438-6_36">10.1007/978-3-642-22438-6_36</a>.
  short: T. Wies, M. Muñiz, V. Kuncak, in:, Springer, 2011, pp. 476–491.
conference:
  end_date: 2011-08-05
  location: Wrocław, Poland
  name: 'CADE 23: Automated Deduction '
  start_date: 2011-07-31
corr_author: '1'
date_created: 2018-12-11T12:02:40Z
date_published: 2011-07-19T00:00:00Z
date_updated: 2024-10-09T20:54:31Z
day: '19'
department:
- _id: ToHe
doi: 10.1007/978-3-642-22438-6_36
fulldoi: https://doi.org/10.1007/978-3-642-22438-6_36
intvolume: '      6803'
language:
- iso: eng
month: '07'
oa_version: None
page: 476 - 491
publication_status: published
publisher: Springer
publist_id: '3312'
quality_controlled: '1'
related_material:
  record:
  - id: '5383'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: An efficient decision procedure for imperative tree data structures
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 6803
year: '2011'
...
