[{"date_created":"2023-02-20T08:13:36Z","publication":"The Cryosphere","year":"2018","date_updated":"2023-02-28T11:39:26Z","publication_identifier":{"issn":["1994-0424"]},"abstract":[{"text":"Ice cliffs within a supraglacial debris cover have been identified as a source for high ablation relative to the surrounding debris-covered area. Due to their small relative size and steep orientation, ice cliffs are difficult to detect using nadir-looking space borne sensors. The method presented here uses surface slopes calculated from digital elevation model (DEM) data to map ice cliff geometry and produce an ice cliff probability map. Surface slope thresholds, which can be sensitive to geographic location and/or data quality, are selected automatically. The method also attempts to include area at the (often narrowing) ends of ice cliffs which could otherwise be neglected due to signal saturation in surface slope data. The method was calibrated in the eastern Alaska Range, Alaska, USA, against a control ice cliff dataset derived from high-resolution visible and thermal data. Using the same input parameter set that performed best in Alaska, the method was tested against ice cliffs manually mapped in the Khumbu Himal, Nepal. Our results suggest the method can accommodate different glaciological settings and different DEM data sources without a data intensive (high-resolution, multi-data source) recalibration.","lang":"eng"}],"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"date_published":"2018-05-31T00:00:00Z","title":"Automated detection of ice cliffs within supraglacial debris cover","article_processing_charge":"No","intvolume":"        12","_id":"12606","type":"journal_article","publication_status":"published","page":"1811-1829","citation":{"mla":"Herreid, Sam, and Francesca Pellicciotti. “Automated Detection of Ice Cliffs within Supraglacial Debris Cover.” <i>The Cryosphere</i>, vol. 12, no. 5, Copernicus Publications, 2018, pp. 1811–29, doi:<a href=\"https://doi.org/10.5194/tc-12-1811-2018\">10.5194/tc-12-1811-2018</a>.","ama":"Herreid S, Pellicciotti F. Automated detection of ice cliffs within supraglacial debris cover. <i>The Cryosphere</i>. 2018;12(5):1811-1829. doi:<a href=\"https://doi.org/10.5194/tc-12-1811-2018\">10.5194/tc-12-1811-2018</a>","ista":"Herreid S, Pellicciotti F. 2018. Automated detection of ice cliffs within supraglacial debris cover. The Cryosphere. 12(5), 1811–1829.","chicago":"Herreid, Sam, and Francesca Pellicciotti. “Automated Detection of Ice Cliffs within Supraglacial Debris Cover.” <i>The Cryosphere</i>. Copernicus Publications, 2018. <a href=\"https://doi.org/10.5194/tc-12-1811-2018\">https://doi.org/10.5194/tc-12-1811-2018</a>.","apa":"Herreid, S., &#38; Pellicciotti, F. (2018). Automated detection of ice cliffs within supraglacial debris cover. <i>The Cryosphere</i>. Copernicus Publications. <a href=\"https://doi.org/10.5194/tc-12-1811-2018\">https://doi.org/10.5194/tc-12-1811-2018</a>","short":"S. Herreid, F. Pellicciotti, The Cryosphere 12 (2018) 1811–1829.","ieee":"S. Herreid and F. Pellicciotti, “Automated detection of ice cliffs within supraglacial debris cover,” <i>The Cryosphere</i>, vol. 12, no. 5. Copernicus Publications, pp. 1811–1829, 2018."},"scopus_import":"1","day":"31","author":[{"last_name":"Herreid","full_name":"Herreid, Sam","first_name":"Sam"},{"last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"volume":12,"publisher":"Copernicus Publications","quality_controlled":"1","doi":"10.5194/tc-12-1811-2018","oa_version":"Published Version","month":"05","article_type":"original","issue":"5","keyword":["Earth-Surface Processes","Water Science and Technology"],"main_file_link":[{"url":"https://doi.org/10.5194/tc-12-1811-2018","open_access":"1"}],"status":"public"},{"scopus_import":"1","page":"4369-4374","publication_status":"published","citation":{"short":"P. Buri, F. Pellicciotti, PNAS 115 (2018) 4369–4374.","apa":"Buri, P., &#38; Pellicciotti, F. (2018). Aspect controls the survival of ice cliffs on debris-covered glaciers. <i>PNAS</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1713892115\">https://doi.org/10.1073/pnas.1713892115</a>","ista":"Buri P, Pellicciotti F. 2018. Aspect controls the survival of ice cliffs on debris-covered glaciers. PNAS. 115(17), 4369–4374.","ama":"Buri P, Pellicciotti F. Aspect controls the survival of ice cliffs on debris-covered glaciers. <i>PNAS</i>. 2018;115(17):4369-4374. doi:<a href=\"https://doi.org/10.1073/pnas.1713892115\">10.1073/pnas.1713892115</a>","mla":"Buri, Pascal, and Francesca Pellicciotti. “Aspect Controls the Survival of Ice Cliffs on Debris-Covered Glaciers.” <i>PNAS</i>, vol. 115, no. 17, Proceedings of the National Academy of Sciences, 2018, pp. 4369–74, doi:<a href=\"https://doi.org/10.1073/pnas.1713892115\">10.1073/pnas.1713892115</a>.","chicago":"Buri, Pascal, and Francesca Pellicciotti. “Aspect Controls the Survival of Ice Cliffs on Debris-Covered Glaciers.” <i>PNAS</i>. Proceedings of the National Academy of Sciences, 2018. <a href=\"https://doi.org/10.1073/pnas.1713892115\">https://doi.org/10.1073/pnas.1713892115</a>.","ieee":"P. Buri and F. Pellicciotti, “Aspect controls the survival of ice cliffs on debris-covered glaciers,” <i>PNAS</i>, vol. 115, no. 17. Proceedings of the National Academy of Sciences, pp. 4369–4374, 2018."},"volume":115,"publisher":"Proceedings of the National Academy of Sciences","day":"09","author":[{"full_name":"Buri, Pascal","last_name":"Buri","first_name":"Pascal"},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"quality_controlled":"1","doi":"10.1073/pnas.1713892115","issue":"17","main_file_link":[{"url":"https://doi.org/10.1073/pnas.1713892115","open_access":"1"}],"status":"public","oa_version":"Published Version","article_type":"original","month":"04","abstract":[{"lang":"eng","text":"Supraglacial ice cliffs exist on debris-covered glaciers worldwide, but despite their importance as melt hot spots, their life cycle is little understood. Early field observations had advanced a hypothesis of survival of north-facing and disappearance of south-facing cliffs, which is central for predicting the contribution of cliffs to total glacier mass losses. Their role as windows of energy transfer suggests they may explain the anomalously high mass losses of debris-covered glaciers in High Mountain Asia (HMA) despite the insulating debris, currently at the center of a debated controversy. We use a 3D model of cliff evolution coupled to very high-resolution topographic data to demonstrate that ice cliffs facing south (in the Northern Hemisphere) disappear within a few months due to enhanced solar radiation receipts and that aspect is the key control on cliffs evolution. We reproduce continuous flattening of south-facing cliffs, a result of their vertical gradient of incoming solar radiation and sky view factor. Our results establish that only north-facing cliffs are recurrent features and thus stable contributors to the melting of debris-covered glaciers. Satellite observations and mass balance modeling confirms that few south-facing cliffs of small size exist on the glaciers of Langtang, and their contribution to the glacier volume losses is very small (∼1%). This has major implications for the mass balance of HMA debris-covered glaciers as it provides the basis for new parameterizations of cliff evolution and distribution to constrain volume losses in a region where glaciers are highly relevant as water sources for millions of people."}],"year":"2018","date_updated":"2023-02-28T11:35:18Z","publication":"PNAS","date_created":"2023-02-20T08:13:41Z","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","date_published":"2018-04-09T00:00:00Z","title":"Aspect controls the survival of ice cliffs on debris-covered glaciers","article_processing_charge":"No","language":[{"iso":"eng"}],"type":"journal_article","_id":"12607","intvolume":"       115"},{"publist_id":"7926","publisher":"Nature Publishing Group","volume":14,"user_id":"2EBD1598-F248-11E8-B48F-1D18A9856A87","author":[{"orcid":"0000-0002-2299-3176","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","last_name":"Waitukaitis","full_name":"Waitukaitis, Scott R"}],"extern":"1","day":"28","abstract":[{"lang":"eng","text":"The ideas of topology are breaking ground in origami-based metamaterials. Experiments now show that certain shapes — doughnuts included — exhibit topological bistability, and can be made to click between different topologically stable states."}],"citation":{"short":"S.R. Waitukaitis, Nature Physics 14 (2018) 777–778.","apa":"Waitukaitis, S. R. (2018). Clicks for doughnuts. <i>Nature Physics</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41567-018-0160-6\">https://doi.org/10.1038/s41567-018-0160-6</a>","ista":"Waitukaitis SR. 2018. Clicks for doughnuts. Nature Physics. 14(8), 777–778.","mla":"Waitukaitis, Scott R. “Clicks for Doughnuts.” <i>Nature Physics</i>, vol. 14, no. 8, Nature Publishing Group, 2018, pp. 777–78, doi:<a href=\"https://doi.org/10.1038/s41567-018-0160-6\">10.1038/s41567-018-0160-6</a>.","chicago":"Waitukaitis, Scott R. “Clicks for Doughnuts.” <i>Nature Physics</i>. Nature Publishing Group, 2018. <a href=\"https://doi.org/10.1038/s41567-018-0160-6\">https://doi.org/10.1038/s41567-018-0160-6</a>.","ama":"Waitukaitis SR. Clicks for doughnuts. <i>Nature Physics</i>. 2018;14(8):777-778. doi:<a href=\"https://doi.org/10.1038/s41567-018-0160-6\">10.1038/s41567-018-0160-6</a>","ieee":"S. R. Waitukaitis, “Clicks for doughnuts,” <i>Nature Physics</i>, vol. 14, no. 8. Nature Publishing Group, pp. 777–778, 2018."},"year":"2018","date_updated":"2021-01-12T06:49:31Z","page":"777 - 778","publication_status":"published","date_created":"2018-12-11T11:44:46Z","publication":"Nature Physics","type":"journal_article","_id":"127","status":"public","issue":"8","month":"05","intvolume":"        14","oa_version":"None","title":"Clicks for doughnuts","date_published":"2018-05-28T00:00:00Z","doi":"10.1038/s41567-018-0160-6","language":[{"iso":"eng"}]},{"quality_controlled":"1","doi":"10.1145/3197517.3201381","status":"public","article_number":"136","issue":"4","ddc":["004"],"month":"08","oa_version":"Submitted Version","pubrep_id":"1038","ec_funded":1,"scopus_import":"1","isi":1,"file":[{"file_name":"IST-2018-1038-v1+1_metamolds_authorversion.pdf","access_level":"open_access","file_size":91939066,"relation":"main_file","content_type":"application/pdf","date_updated":"2020-07-14T12:44:43Z","file_id":"5374","date_created":"2018-12-12T10:18:52Z","creator":"system","checksum":"61d46273dca4de626accef1d17a0aaad"}],"citation":{"ieee":"T. Alderighi, L. Malomo, D. Giorgi, N. Pietroni, B. Bickel, and P. Cignoni, “Metamolds: Computational design of silicone molds,” <i>ACM Trans. Graph.</i>, vol. 37, no. 4. ACM, 2018.","ista":"Alderighi T, Malomo L, Giorgi D, Pietroni N, Bickel B, Cignoni P. 2018. Metamolds: Computational design of silicone molds. ACM Trans. Graph. 37(4), 136.","chicago":"Alderighi, Thomas, Luigi Malomo, Daniela Giorgi, Nico Pietroni, Bernd Bickel, and Paolo Cignoni. “Metamolds: Computational Design of Silicone Molds.” <i>ACM Trans. Graph.</i> ACM, 2018. <a href=\"https://doi.org/10.1145/3197517.3201381\">https://doi.org/10.1145/3197517.3201381</a>.","mla":"Alderighi, Thomas, et al. “Metamolds: Computational Design of Silicone Molds.” <i>ACM Trans. Graph.</i>, vol. 37, no. 4, 136, ACM, 2018, doi:<a href=\"https://doi.org/10.1145/3197517.3201381\">10.1145/3197517.3201381</a>.","ama":"Alderighi T, Malomo L, Giorgi D, Pietroni N, Bickel B, Cignoni P. Metamolds: Computational design of silicone molds. <i>ACM Trans Graph</i>. 2018;37(4). doi:<a href=\"https://doi.org/10.1145/3197517.3201381\">10.1145/3197517.3201381</a>","apa":"Alderighi, T., Malomo, L., Giorgi, D., Pietroni, N., Bickel, B., &#38; Cignoni, P. (2018). Metamolds: Computational design of silicone molds. <i>ACM Trans. Graph.</i> ACM. <a href=\"https://doi.org/10.1145/3197517.3201381\">https://doi.org/10.1145/3197517.3201381</a>","short":"T. Alderighi, L. Malomo, D. Giorgi, N. Pietroni, B. Bickel, P. Cignoni, ACM Trans. Graph. 37 (2018)."},"publication_status":"published","project":[{"_id":"24F9549A-B435-11E9-9278-68D0E5697425","grant_number":"715767","call_identifier":"H2020","name":"MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and Modeling"}],"publisher":"ACM","volume":37,"author":[{"first_name":"Thomas","full_name":"Alderighi, Thomas","last_name":"Alderighi"},{"first_name":"Luigi","full_name":"Malomo, Luigi","last_name":"Malomo"},{"first_name":"Daniela","full_name":"Giorgi, Daniela","last_name":"Giorgi"},{"last_name":"Pietroni","full_name":"Pietroni, Nico","first_name":"Nico"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","first_name":"Bernd","orcid":"0000-0001-6511-9385","full_name":"Bickel, Bernd","last_name":"Bickel"},{"last_name":"Cignoni","full_name":"Cignoni, Paolo","first_name":"Paolo"}],"related_material":{"link":[{"relation":"press_release","description":"News on IST Homepage","url":"https://ist.ac.at/en/news/metamolds-molding-a-mold/"}]},"day":"04","article_processing_charge":"No","title":"Metamolds: Computational design of silicone molds","date_published":"2018-08-04T00:00:00Z","file_date_updated":"2020-07-14T12:44:43Z","language":[{"iso":"eng"}],"_id":"13","type":"journal_article","has_accepted_license":"1","intvolume":"        37","abstract":[{"lang":"eng","text":"We propose a new method for fabricating digital objects through reusable silicone molds. Molds are generated by casting liquid silicone into custom 3D printed containers called metamolds. Metamolds automatically define the cuts that are needed to extract the cast object from the silicone mold. The shape of metamolds is designed through a novel segmentation technique, which takes into account both geometric and topological constraints involved in the process of mold casting. Our technique is simple, does not require changing the shape or topology of the input objects, and only requires off-the- shelf materials and technologies. We successfully tested our method on a set of challenging examples with complex shapes and rich geometric detail. © 2018 Association for Computing Machinery."}],"external_id":{"isi":["000448185000097"]},"year":"2018","date_updated":"2025-04-14T07:28:57Z","date_created":"2018-12-11T11:44:09Z","publication":"ACM Trans. Graph.","publist_id":"8043","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","department":[{"_id":"BeBi"}]},{"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Social network plasticity decreases disease transmission in a eusocial insect","article_processing_charge":"No","doi":"10.5281/ZENODO.1322669","date_published":"2018-10-23T00:00:00Z","_id":"13055","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/zenodo.1480665"}],"type":"research_data_reference","ddc":["570"],"month":"10","oa_version":"Published Version","abstract":[{"lang":"eng","text":"Dataset for manuscript 'Social network plasticity decreases disease transmission in a eusocial insect'\r\nCompared to previous versions: - raw image files added\r\n                                                     - correction of URLs within README.txt file\r\n"}],"citation":{"apa":"Stroeymeyt, N., Grasse, A. V., Crespi, A., Mersch, D., Cremer, S., &#38; Keller, L. (2018). Social network plasticity decreases disease transmission in a eusocial insect. Zenodo. <a href=\"https://doi.org/10.5281/ZENODO.1322669\">https://doi.org/10.5281/ZENODO.1322669</a>","short":"N. Stroeymeyt, A.V. Grasse, A. Crespi, D. Mersch, S. Cremer, L. Keller, (2018).","ama":"Stroeymeyt N, Grasse AV, Crespi A, Mersch D, Cremer S, Keller L. Social network plasticity decreases disease transmission in a eusocial insect. 2018. doi:<a href=\"https://doi.org/10.5281/ZENODO.1322669\">10.5281/ZENODO.1322669</a>","ista":"Stroeymeyt N, Grasse AV, Crespi A, Mersch D, Cremer S, Keller L. 2018. Social network plasticity decreases disease transmission in a eusocial insect, Zenodo, <a href=\"https://doi.org/10.5281/ZENODO.1322669\">10.5281/ZENODO.1322669</a>.","chicago":"Stroeymeyt, Nathalie, Anna V Grasse, Alessandro Crespi, Danielle Mersch, Sylvia Cremer, and Laurent Keller. “Social Network Plasticity Decreases Disease Transmission in a Eusocial Insect.” Zenodo, 2018. <a href=\"https://doi.org/10.5281/ZENODO.1322669\">https://doi.org/10.5281/ZENODO.1322669</a>.","mla":"Stroeymeyt, Nathalie, et al. <i>Social Network Plasticity Decreases Disease Transmission in a Eusocial Insect</i>. Zenodo, 2018, doi:<a href=\"https://doi.org/10.5281/ZENODO.1322669\">10.5281/ZENODO.1322669</a>.","ieee":"N. Stroeymeyt, A. V. Grasse, A. Crespi, D. Mersch, S. Cremer, and L. Keller, “Social network plasticity decreases disease transmission in a eusocial insect.” Zenodo, 2018."},"date_updated":"2026-06-18T19:15:22Z","year":"2018","date_created":"2023-05-23T13:24:51Z","publisher":"Zenodo","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Nathalie","last_name":"Stroeymeyt","full_name":"Stroeymeyt, Nathalie"},{"id":"406F989C-F248-11E8-B48F-1D18A9856A87","first_name":"Anna V","last_name":"Grasse","full_name":"Grasse, Anna V"},{"first_name":"Alessandro","last_name":"Crespi","full_name":"Crespi, Alessandro"},{"last_name":"Mersch","full_name":"Mersch, Danielle","first_name":"Danielle"},{"orcid":"0000-0002-2193-3868","first_name":"Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","full_name":"Cremer, Sylvia","last_name":"Cremer"},{"last_name":"Keller","full_name":"Keller, Laurent","first_name":"Laurent"}],"related_material":{"record":[{"id":"7","relation":"used_in_publication","status":"public"}]},"department":[{"_id":"SyCr"}],"day":"23"},{"citation":{"ieee":"E. Garriga <i>et al.</i>, “Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method.” Zenodo, 2018.","short":"E. Garriga, P. di Tommaso, C. Magis, I. Erb, L. Mansouri, A. Baltzis, H. Laayouni, F. Kondrashov, E. Floden, C. Notredame, (2018).","apa":"Garriga, E., di Tommaso, P., Magis, C., Erb, I., Mansouri, L., Baltzis, A., … Notredame, C. (2018). Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method. Zenodo. <a href=\"https://doi.org/10.5281/ZENODO.2025846\">https://doi.org/10.5281/ZENODO.2025846</a>","mla":"Garriga, Edgar, et al. <i>Fast and Accurate Large Multiple Sequence Alignments with a Root-to-Leaf Regressive Method</i>. Zenodo, 2018, doi:<a href=\"https://doi.org/10.5281/ZENODO.2025846\">10.5281/ZENODO.2025846</a>.","ama":"Garriga E, di Tommaso P, Magis C, et al. Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method. 2018. doi:<a href=\"https://doi.org/10.5281/ZENODO.2025846\">10.5281/ZENODO.2025846</a>","chicago":"Garriga, Edgar, Paolo di Tommaso, Cedrik Magis, Ionas Erb, Leila Mansouri, Athanasios Baltzis, Hafid Laayouni, Fyodor Kondrashov, Evan Floden, and Cedric Notredame. “Fast and Accurate Large Multiple Sequence Alignments with a Root-to-Leaf Regressive Method.” Zenodo, 2018. <a href=\"https://doi.org/10.5281/ZENODO.2025846\">https://doi.org/10.5281/ZENODO.2025846</a>.","ista":"Garriga E, di Tommaso P, Magis C, Erb I, Mansouri L, Baltzis A, Laayouni H, Kondrashov F, Floden E, Notredame C. 2018. Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method, Zenodo, <a href=\"https://doi.org/10.5281/ZENODO.2025846\">10.5281/ZENODO.2025846</a>."},"date_updated":"2025-07-10T11:54:19Z","year":"2018","date_created":"2023-05-23T16:08:20Z","abstract":[{"lang":"eng","text":"This dataset contains a GitHub repository containing all the data, analysis, Nextflow workflows and Jupyter notebooks to replicate the manuscript titled \"Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method\".\r\nIt also contains the Multiple Sequence Alignments (MSAs) generated and well as the main figures and tables from the manuscript.\r\nThe repository is also available at GitHub (https://github.com/cbcrg/dpa-analysis) release `v1.2`.\r\nFor details on how to use the regressive alignment algorithm, see the T-Coffee software suite (https://github.com/cbcrg/tcoffee)."}],"author":[{"first_name":"Edgar","full_name":"Garriga, Edgar","last_name":"Garriga"},{"last_name":"di Tommaso","full_name":"di Tommaso, Paolo","first_name":"Paolo"},{"last_name":"Magis","full_name":"Magis, Cedrik","first_name":"Cedrik"},{"first_name":"Ionas","last_name":"Erb","full_name":"Erb, Ionas"},{"last_name":"Mansouri","full_name":"Mansouri, Leila","first_name":"Leila"},{"first_name":"Athanasios","last_name":"Baltzis","full_name":"Baltzis, Athanasios"},{"full_name":"Laayouni, Hafid","last_name":"Laayouni","first_name":"Hafid"},{"last_name":"Kondrashov","full_name":"Kondrashov, Fyodor","orcid":"0000-0001-8243-4694","first_name":"Fyodor","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Floden","full_name":"Floden, Evan","first_name":"Evan"},{"last_name":"Notredame","full_name":"Notredame, Cedric","first_name":"Cedric"}],"department":[{"_id":"FyKo"}],"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"7181"}]},"day":"07","publisher":"Zenodo","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_processing_charge":"No","title":"Fast and accurate large multiple sequence alignments with a root-to-leaf regressive method","date_published":"2018-12-07T00:00:00Z","doi":"10.5281/ZENODO.2025846","month":"12","oa_version":"Published Version","_id":"13059","status":"public","type":"research_data_reference","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/zenodo.3271452"}],"ddc":["570"]},{"date_published":"2018-08-13T00:00:00Z","article_processing_charge":"No","title":"Evolution of gene dosage on the Z-chromosome of schistosome parasites","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file_date_updated":"2020-07-14T12:44:43Z","language":[{"iso":"eng"}],"has_accepted_license":"1","type":"journal_article","_id":"131","intvolume":"         7","external_id":{"isi":["000441388200001"]},"abstract":[{"lang":"eng","text":"XY systems usually show chromosome-wide compensation of X-linked genes, while in many ZW systems, compensation is restricted to a minority of dosage-sensitive genes. Why such differences arose is still unclear. Here, we combine comparative genomics, transcriptomics and proteomics to obtain a complete overview of the evolution of gene dosage on the Z-chromosome of Schistosoma parasites. We compare the Z-chromosome gene content of African (Schistosoma mansoni and S. haematobium) and Asian (S. japonicum) schistosomes and describe lineage-specific evolutionary strata. We use these to assess gene expression evolution following sex-linkage. The resulting patterns suggest a reduction in expression of Z-linked genes in females, combined with upregulation of the Z in both sexes, in line with the first step of Ohno’s classic model of dosage compensation evolution. Quantitative proteomics suggest that post-transcriptional mechanisms do not play a major role in balancing the expression of Z-linked genes. "}],"publication":"eLife","date_created":"2018-12-11T11:44:47Z","year":"2018","date_updated":"2025-04-15T08:18:37Z","acknowledgement":"We are grateful to Lu Dabing (Soochow University, Suzhou, China) for providing Schistosoma japonicum samples, to Ariana Macon (IST Austria) and Georgette Stovall (JLU Giessen) for technical assistance, to IT support at IST Austria for providing optimal environment to bioinformatic analyses, and to the Vicoso lab for comments on the manuscript.","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","oa":1,"publist_id":"7792","department":[{"_id":"BeVi"}],"quality_controlled":"1","doi":"10.7554/eLife.35684","ddc":["570"],"article_number":"e35684","status":"public","oa_version":"Published Version","month":"08","article_type":"original","scopus_import":"1","publication_status":"published","file":[{"creator":"dernst","checksum":"d6331d4385b1fffd6b47b45d5949d841","access_level":"open_access","file_size":3158125,"relation":"main_file","file_name":"2018_eLife_Picard.pdf","date_updated":"2020-07-14T12:44:43Z","file_id":"5695","date_created":"2018-12-17T11:55:05Z","content_type":"application/pdf"}],"isi":1,"citation":{"ista":"Picard MAL, Cosseau C, Ferré S, Quack T, Grevelding C, Couté Y, Vicoso B. 2018. Evolution of gene dosage on the Z-chromosome of schistosome parasites. eLife. 7, e35684.","chicago":"Picard, Marion A L, Celine Cosseau, Sabrina Ferré, Thomas Quack, Christoph Grevelding, Yohann Couté, and Beatriz Vicoso. “Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites.” <i>ELife</i>. eLife Sciences Publications, 2018. <a href=\"https://doi.org/10.7554/eLife.35684\">https://doi.org/10.7554/eLife.35684</a>.","mla":"Picard, Marion A. L., et al. “Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites.” <i>ELife</i>, vol. 7, e35684, eLife Sciences Publications, 2018, doi:<a href=\"https://doi.org/10.7554/eLife.35684\">10.7554/eLife.35684</a>.","ama":"Picard MAL, Cosseau C, Ferré S, et al. Evolution of gene dosage on the Z-chromosome of schistosome parasites. <i>eLife</i>. 2018;7. doi:<a href=\"https://doi.org/10.7554/eLife.35684\">10.7554/eLife.35684</a>","short":"M.A.L. Picard, C. Cosseau, S. Ferré, T. Quack, C. Grevelding, Y. Couté, B. Vicoso, ELife 7 (2018).","apa":"Picard, M. A. L., Cosseau, C., Ferré, S., Quack, T., Grevelding, C., Couté, Y., &#38; Vicoso, B. (2018). Evolution of gene dosage on the Z-chromosome of schistosome parasites. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.35684\">https://doi.org/10.7554/eLife.35684</a>","ieee":"M. A. L. Picard <i>et al.</i>, “Evolution of gene dosage on the Z-chromosome of schistosome parasites,” <i>eLife</i>, vol. 7. eLife Sciences Publications, 2018."},"volume":7,"publisher":"eLife Sciences Publications","project":[{"name":"Sex chromosome evolution under male- and female- heterogamety","grant_number":"P28842-B22","call_identifier":"FWF","_id":"250ED89C-B435-11E9-9278-68D0E5697425"}],"day":"13","related_material":{"record":[{"id":"5586","status":"public","relation":"popular_science"}]},"author":[{"first_name":"Marion A","id":"2C921A7A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8101-2518","last_name":"Picard","full_name":"Picard, Marion A"},{"first_name":"Celine","last_name":"Cosseau","full_name":"Cosseau, Celine"},{"first_name":"Sabrina","last_name":"Ferré","full_name":"Ferré, Sabrina"},{"first_name":"Thomas","full_name":"Quack, Thomas","last_name":"Quack"},{"last_name":"Grevelding","full_name":"Grevelding, Christoph","first_name":"Christoph"},{"last_name":"Couté","full_name":"Couté, Yohann","first_name":"Yohann"},{"first_name":"Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4579-8306","last_name":"Vicoso","full_name":"Vicoso, Beatriz"}]},{"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_processing_charge":"No","title":"Defining lineage potential and fate behavior of precursors during pancreas development","date_published":"2018-08-06T00:00:00Z","language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:44:43Z","_id":"132","type":"journal_article","has_accepted_license":"1","intvolume":"        46","abstract":[{"text":"Pancreas development involves a coordinated process in which an early phase of cell segregation is followed by a longer phase of lineage restriction, expansion, and tissue remodeling. By combining clonal tracing and whole-mount reconstruction with proliferation kinetics and single-cell transcriptional profiling, we define the functional basis of pancreas morphogenesis. We show that the large-scale organization of mouse pancreas can be traced to the activity of self-renewing precursors positioned at the termini of growing ducts, which act collectively to drive serial rounds of stochastic ductal bifurcation balanced by termination. During this phase of branching morphogenesis, multipotent precursors become progressively fate-restricted, giving rise to self-renewing acinar-committed precursors that are conveyed with growing ducts, as well as ductal progenitors that expand the trailing ducts and give rise to delaminating endocrine cells. These findings define quantitatively how the functional behavior and lineage progression of precursor pools determine the large-scale patterning of pancreatic sub-compartments.","lang":"eng"}],"external_id":{"isi":["000441327300012"]},"acknowledgement":"E.H. is funded by a Junior Research Fellowship from Trinity College, Cam-bridge, a Sir Henry Wellcome Fellowship from the Wellcome Trust, and theBettencourt-Schueller Young Researcher Prize for support.","date_updated":"2023-09-11T12:52:41Z","year":"2018","publication":"Developmental Cell","date_created":"2018-12-11T11:44:48Z","publist_id":"7791","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","department":[{"_id":"EdHa"}],"quality_controlled":"1","doi":"10.1016/j.devcel.2018.06.028","status":"public","ddc":["570"],"issue":"3","article_type":"original","month":"08","oa_version":"Published Version","scopus_import":"1","file":[{"checksum":"78d2062b9e3c3b90fe71545aeb6d2f65","creator":"dernst","date_created":"2018-12-17T10:49:49Z","file_id":"5694","date_updated":"2020-07-14T12:44:43Z","content_type":"application/pdf","access_level":"open_access","file_size":8948384,"relation":"main_file","file_name":"2018_DevelopmentalCell_Sznurkowska.pdf"}],"isi":1,"citation":{"ama":"Sznurkowska M, Hannezo EB, Azzarelli R, et al. Defining lineage potential and fate behavior of precursors during pancreas development. <i>Developmental Cell</i>. 2018;46(3):360-375. doi:<a href=\"https://doi.org/10.1016/j.devcel.2018.06.028\">10.1016/j.devcel.2018.06.028</a>","ista":"Sznurkowska M, Hannezo EB, Azzarelli R, Rulands S, Nestorowa S, Hindley C, Nichols J, Göttgens B, Huch M, Philpott A, Simons B. 2018. Defining lineage potential and fate behavior of precursors during pancreas development. Developmental Cell. 46(3), 360–375.","mla":"Sznurkowska, Magdalena, et al. “Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.” <i>Developmental Cell</i>, vol. 46, no. 3, Cell Press, 2018, pp. 360–75, doi:<a href=\"https://doi.org/10.1016/j.devcel.2018.06.028\">10.1016/j.devcel.2018.06.028</a>.","chicago":"Sznurkowska, Magdalena, Edouard B Hannezo, Roberta Azzarelli, Steffen Rulands, Sonia Nestorowa, Christopher Hindley, Jennifer Nichols, et al. “Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.” <i>Developmental Cell</i>. Cell Press, 2018. <a href=\"https://doi.org/10.1016/j.devcel.2018.06.028\">https://doi.org/10.1016/j.devcel.2018.06.028</a>.","short":"M. Sznurkowska, E.B. Hannezo, R. Azzarelli, S. Rulands, S. Nestorowa, C. Hindley, J. Nichols, B. Göttgens, M. Huch, A. Philpott, B. Simons, Developmental Cell 46 (2018) 360–375.","apa":"Sznurkowska, M., Hannezo, E. B., Azzarelli, R., Rulands, S., Nestorowa, S., Hindley, C., … Simons, B. (2018). Defining lineage potential and fate behavior of precursors during pancreas development. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2018.06.028\">https://doi.org/10.1016/j.devcel.2018.06.028</a>","ieee":"M. Sznurkowska <i>et al.</i>, “Defining lineage potential and fate behavior of precursors during pancreas development,” <i>Developmental Cell</i>, vol. 46, no. 3. Cell Press, pp. 360–375, 2018."},"page":"360 - 375","publication_status":"published","publisher":"Cell Press","volume":46,"author":[{"full_name":"Sznurkowska, Magdalena","last_name":"Sznurkowska","first_name":"Magdalena"},{"orcid":"0000-0001-6005-1561","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo","full_name":"Hannezo, Edouard B"},{"last_name":"Azzarelli","full_name":"Azzarelli, Roberta","first_name":"Roberta"},{"first_name":"Steffen","full_name":"Rulands, Steffen","last_name":"Rulands"},{"first_name":"Sonia","last_name":"Nestorowa","full_name":"Nestorowa, Sonia"},{"full_name":"Hindley, Christopher","last_name":"Hindley","first_name":"Christopher"},{"last_name":"Nichols","full_name":"Nichols, Jennifer","first_name":"Jennifer"},{"first_name":"Berthold","full_name":"Göttgens, Berthold","last_name":"Göttgens"},{"full_name":"Huch, Meritxell","last_name":"Huch","first_name":"Meritxell"},{"first_name":"Anna","last_name":"Philpott","full_name":"Philpott, Anna"},{"last_name":"Simons","full_name":"Simons, Benjamin","first_name":"Benjamin"}],"day":"06"},{"type":"journal_article","_id":"13255","intvolume":"        10","date_published":"2018-08-17T00:00:00Z","pmid":1,"title":"Supported two-dimensional materials under ion irradiation: The substrate governs defect production","article_processing_charge":"No","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","external_id":{"pmid":["30117320"]},"abstract":[{"text":"Focused ion beams perfectly suit for patterning two-dimensional (2D) materials, but the optimization of irradiation parameters requires full microscopic understanding of defect production mechanisms. In contrast to freestanding 2D systems, the details of damage creation in supported 2D materials are not fully understood, whereas the majority of experiments have been carried out for 2D targets deposited on substrates. Here, we suggest a universal and computationally efficient scheme to model the irradiation of supported 2D materials, which combines analytical potential molecular dynamics with Monte Carlo simulations and makes it possible to independently assess the contributions to the damage from backscattered ions and atoms sputtered from the substrate. Using the scheme, we study the defect production in graphene and MoS2 sheets, which are the two most important and wide-spread 2D materials, deposited on a SiO2 substrate. For helium and neon ions with a wide range of initial ion energies including those used in a commercial helium ion microscope (HIM), we demonstrate that depending on the ion energy and mass, the defect production in 2D systems can be dominated by backscattered ions and sputtered substrate atoms rather than by the direct ion impacts and that the amount of damage in 2D materials heavily depends on whether a substrate is present or not. We also study the factors which limit the spatial resolution of the patterning process. Our results, which agree well with the available experimental data, provide not only insights into defect production but also quantitative information, which can be used for the minimization of damage during imaging in HIM or optimization of the patterning process.","lang":"eng"}],"year":"2018","date_updated":"2023-08-01T07:18:30Z","publication":"ACS Applied Materials & Interfaces","date_created":"2023-07-21T11:43:00Z","publication_identifier":{"issn":["1944-8244","1944-8252"]},"keyword":["General Materials Science"],"issue":"36","status":"public","oa_version":"None","article_type":"original","month":"08","quality_controlled":"1","doi":"10.1021/acsami.8b08471","volume":10,"publisher":"American Chemical Society","day":"17","author":[{"full_name":"Kretschmer, Silvan","last_name":"Kretschmer","first_name":"Silvan"},{"full_name":"Maslov, Mikhail","last_name":"Maslov","id":"2E65BB0E-F248-11E8-B48F-1D18A9856A87","first_name":"Mikhail","orcid":"0000-0003-4074-2570"},{"first_name":"Sadegh","full_name":"Ghaderzadeh, Sadegh","last_name":"Ghaderzadeh"},{"full_name":"Ghorbani-Asl, Mahdi","last_name":"Ghorbani-Asl","first_name":"Mahdi"},{"full_name":"Hlawacek, Gregor","last_name":"Hlawacek","first_name":"Gregor"},{"last_name":"Krasheninnikov","full_name":"Krasheninnikov, Arkady V.","first_name":"Arkady V."}],"publication_status":"published","page":"30827-30836","citation":{"ieee":"S. Kretschmer, M. Maslov, S. Ghaderzadeh, M. Ghorbani-Asl, G. Hlawacek, and A. V. Krasheninnikov, “Supported two-dimensional materials under ion irradiation: The substrate governs defect production,” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 10, no. 36. American Chemical Society, pp. 30827–30836, 2018.","short":"S. Kretschmer, M. Maslov, S. Ghaderzadeh, M. Ghorbani-Asl, G. Hlawacek, A.V. Krasheninnikov, ACS Applied Materials &#38; Interfaces 10 (2018) 30827–30836.","apa":"Kretschmer, S., Maslov, M., Ghaderzadeh, S., Ghorbani-Asl, M., Hlawacek, G., &#38; Krasheninnikov, A. V. (2018). Supported two-dimensional materials under ion irradiation: The substrate governs defect production. <i>ACS Applied Materials &#38; Interfaces</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsami.8b08471\">https://doi.org/10.1021/acsami.8b08471</a>","ama":"Kretschmer S, Maslov M, Ghaderzadeh S, Ghorbani-Asl M, Hlawacek G, Krasheninnikov AV. Supported two-dimensional materials under ion irradiation: The substrate governs defect production. <i>ACS Applied Materials &#38; Interfaces</i>. 2018;10(36):30827-30836. doi:<a href=\"https://doi.org/10.1021/acsami.8b08471\">10.1021/acsami.8b08471</a>","mla":"Kretschmer, Silvan, et al. “Supported Two-Dimensional Materials under Ion Irradiation: The Substrate Governs Defect Production.” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 10, no. 36, American Chemical Society, 2018, pp. 30827–36, doi:<a href=\"https://doi.org/10.1021/acsami.8b08471\">10.1021/acsami.8b08471</a>.","chicago":"Kretschmer, Silvan, Mikhail Maslov, Sadegh Ghaderzadeh, Mahdi Ghorbani-Asl, Gregor Hlawacek, and Arkady V. Krasheninnikov. “Supported Two-Dimensional Materials under Ion Irradiation: The Substrate Governs Defect Production.” <i>ACS Applied Materials &#38; Interfaces</i>. American Chemical Society, 2018. <a href=\"https://doi.org/10.1021/acsami.8b08471\">https://doi.org/10.1021/acsami.8b08471</a>.","ista":"Kretschmer S, Maslov M, Ghaderzadeh S, Ghorbani-Asl M, Hlawacek G, Krasheninnikov AV. 2018. Supported two-dimensional materials under ion irradiation: The substrate governs defect production. ACS Applied Materials &#38; Interfaces. 10(36), 30827–30836."}},{"date_created":"2018-12-11T11:44:48Z","year":"2018","date_updated":"2026-04-08T07:23:52Z","publication_identifier":{"issn":["1868-8969"]},"abstract":[{"lang":"eng","text":"Synchronous programs are easy to specify because the side effects of an operation are finished by the time the invocation of the operation returns to the caller. Asynchronous programs, on the other hand, are difficult to specify because there are side effects due to pending computation scheduled as a result of the invocation of an operation. They are also difficult to verify because of the large number of possible interleavings of concurrent computation threads. We present synchronization, a new proof rule that simplifies the verification of asynchronous programs by introducing the fiction, for proof purposes, that asynchronous operations complete synchronously. Synchronization summarizes an asynchronous computation as immediate atomic effect. Modular verification is enabled via pending asynchronous calls in atomic summaries, and a complementary proof rule that eliminates pending asynchronous calls when components and their specifications are composed. We evaluate synchronization in the context of a multi-layer refinement verification methodology on a collection of benchmark programs."}],"extern":"1","department":[{"_id":"ToHe"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"publist_id":"7790","language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:44:44Z","OA_type":"gold","date_published":"2018-08-13T00:00:00Z","article_processing_charge":"No","title":"Synchronizing the asynchronous","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"       118","has_accepted_license":"1","type":"conference","_id":"133","alternative_title":["LIPIcs"],"publication_status":"published","citation":{"apa":"Kragl, B., Qadeer, S., &#38; Henzinger, T. A. (2018). Synchronizing the asynchronous (Vol. 118). Presented at the CONCUR: International Conference on Concurrency Theory, Beijing, China: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2018.21\">https://doi.org/10.4230/LIPIcs.CONCUR.2018.21</a>","short":"B. Kragl, S. Qadeer, T.A. Henzinger, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018.","ama":"Kragl B, Qadeer S, Henzinger TA. Synchronizing the asynchronous. In: Vol 118. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2018. doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2018.21\">10.4230/LIPIcs.CONCUR.2018.21</a>","mla":"Kragl, Bernhard, et al. <i>Synchronizing the Asynchronous</i>. Vol. 118, 21, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018, doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2018.21\">10.4230/LIPIcs.CONCUR.2018.21</a>.","chicago":"Kragl, Bernhard, Shaz Qadeer, and Thomas A Henzinger. “Synchronizing the Asynchronous,” Vol. 118. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2018.21\">https://doi.org/10.4230/LIPIcs.CONCUR.2018.21</a>.","ista":"Kragl B, Qadeer S, Henzinger TA. 2018. Synchronizing the asynchronous. CONCUR: International Conference on Concurrency Theory, LIPIcs, vol. 118, 21.","ieee":"B. Kragl, S. Qadeer, and T. A. Henzinger, “Synchronizing the asynchronous,” presented at the CONCUR: International Conference on Concurrency Theory, Beijing, China, 2018, vol. 118."},"file":[{"checksum":"c90895f4c5fafc18ddc54d1c8848077e","creator":"system","content_type":"application/pdf","date_created":"2018-12-12T10:18:46Z","date_updated":"2020-07-14T12:44:44Z","file_id":"5368","file_name":"IST-2018-853-v2+2_concur2018.pdf","relation":"main_file","access_level":"open_access","file_size":745438}],"scopus_import":"1","pubrep_id":"1039","day":"13","related_material":{"record":[{"relation":"earlier_version","status":"public","id":"6426"},{"id":"8332","status":"public","relation":"dissertation_contains"}]},"author":[{"orcid":"0000-0001-7745-9117","first_name":"Bernhard","id":"320FC952-F248-11E8-B48F-1D18A9856A87","last_name":"Kragl","full_name":"Kragl, Bernhard"},{"last_name":"Qadeer","full_name":"Qadeer, Shaz","first_name":"Shaz"},{"orcid":"0000−0002−2985−7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","full_name":"Henzinger, Thomas A","last_name":"Henzinger"}],"volume":118,"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","project":[{"call_identifier":"FWF","grant_number":"S11402-N23","_id":"25F2ACDE-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering"},{"name":"Moderne Concurrency Paradigms","call_identifier":"FWF","grant_number":"S11402-N23","_id":"25F5A88A-B435-11E9-9278-68D0E5697425"}],"OA_place":"publisher","quality_controlled":"1","doi":"10.4230/LIPIcs.CONCUR.2018.21","oa_version":"Published Version","conference":{"location":"Beijing, China","start_date":"2018-09-04","name":"CONCUR: International Conference on Concurrency Theory","end_date":"2018-09-07"},"month":"08","ddc":["000"],"article_number":"21","status":"public"},{"language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:45:28Z","article_processing_charge":"No","title":"Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_published":"2018-11-02T00:00:00Z","intvolume":"         9","_id":"21","type":"journal_article","has_accepted_license":"1","acknowledgement":"This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 692692) and the Fond zur Förderung der Wissenschaftlichen Forschung (Z 312-B27, Wittgenstein award), both to P.J..","publication":"Nature Communications","date_created":"2018-12-11T11:44:12Z","year":"2018","date_updated":"2026-06-23T22:30:20Z","abstract":[{"lang":"eng","text":"Parvalbumin-positive (PV+) GABAergic interneurons in hippocampal microcircuits are thought to play a key role in several higher network functions, such as feedforward and feedback inhibition, network oscillations, and pattern separation. Fast lateral inhibition mediated by GABAergic interneurons may implement a winner-takes-all mechanism in the hippocampal input layer. However, it is not clear whether the functional connectivity rules of granule cells (GCs) and interneurons in the dentate gyrus are consistent with such a mechanism. Using simultaneous patch-clamp recordings from up to seven GCs and up to four PV+ interneurons in the dentate gyrus, we find that connectivity is structured in space, synapse-specific, and enriched in specific disynaptic motifs. In contrast to the neocortex, lateral inhibition in the dentate gyrus (in which a GC inhibits neighboring GCs via a PV+ interneuron) is ~ 10-times more abundant than recurrent inhibition (in which a GC inhibits itself). Thus, unique connectivity rules may enable the dentate gyrus to perform specific higher-order computations"}],"external_id":{"isi":["000449069700009"]},"department":[{"_id":"PeJo"}],"publist_id":"8034","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","oa":1,"doi":"10.1038/s41467-018-06899-3","quality_controlled":"1","month":"11","article_type":"original","oa_version":"Published Version","status":"public","issue":"1","ddc":["570"],"article_number":"4605","file":[{"content_type":"application/pdf","date_created":"2018-12-17T15:41:57Z","file_id":"5715","date_updated":"2020-07-14T12:45:28Z","file_name":"2018_NatureComm_Espinoza.pdf","file_size":4651930,"relation":"main_file","access_level":"open_access","checksum":"9fe2a63bd95a5067d896c087d07998f3","creator":"dernst"}],"isi":1,"citation":{"ieee":"C. Espinoza Martinez, J. Guzmán, X. Zhang, and P. M. Jonas, “Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus,” <i>Nature Communications</i>, vol. 9, no. 1. Nature Publishing Group, 2018.","chicago":"Espinoza Martinez, Claudia , José Guzmán, Xiaomin Zhang, and Peter M Jonas. “Parvalbumin+ Interneurons Obey Unique Connectivity Rules and Establish a Powerful Lateral-Inhibition Microcircuit in Dentate Gyrus.” <i>Nature Communications</i>. Nature Publishing Group, 2018. <a href=\"https://doi.org/10.1038/s41467-018-06899-3\">https://doi.org/10.1038/s41467-018-06899-3</a>.","ista":"Espinoza Martinez C, Guzmán J, Zhang X, Jonas PM. 2018. Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus. Nature Communications. 9(1), 4605.","mla":"Espinoza Martinez, Claudia, et al. “Parvalbumin+ Interneurons Obey Unique Connectivity Rules and Establish a Powerful Lateral-Inhibition Microcircuit in Dentate Gyrus.” <i>Nature Communications</i>, vol. 9, no. 1, 4605, Nature Publishing Group, 2018, doi:<a href=\"https://doi.org/10.1038/s41467-018-06899-3\">10.1038/s41467-018-06899-3</a>.","ama":"Espinoza Martinez C, Guzmán J, Zhang X, Jonas PM. Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus. <i>Nature Communications</i>. 2018;9(1). doi:<a href=\"https://doi.org/10.1038/s41467-018-06899-3\">10.1038/s41467-018-06899-3</a>","apa":"Espinoza Martinez, C., Guzmán, J., Zhang, X., &#38; Jonas, P. M. (2018). Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41467-018-06899-3\">https://doi.org/10.1038/s41467-018-06899-3</a>","short":"C. Espinoza Martinez, J. Guzmán, X. Zhang, P.M. Jonas, Nature Communications 9 (2018)."},"publication_status":"published","ec_funded":1,"scopus_import":"1","author":[{"id":"31FFEE2E-F248-11E8-B48F-1D18A9856A87","first_name":"Claudia ","orcid":"0000-0003-4710-2082","last_name":"Espinoza Martinez","full_name":"Espinoza Martinez, Claudia "},{"id":"30CC5506-F248-11E8-B48F-1D18A9856A87","first_name":"José","orcid":"0000-0003-2209-5242","full_name":"Guzmán, José","last_name":"Guzmán"},{"full_name":"Zhang, Xiaomin","last_name":"Zhang","first_name":"Xiaomin","id":"423EC9C2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0256-6529"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M"}],"day":"02","related_material":{"link":[{"url":"https://ist.ac.at/en/news/lateral-inhibition-keeps-similar-memories-apart/","relation":"press_release","description":"News on IST Homepage"}],"record":[{"relation":"dissertation_contains","status":"public","id":"6363"}]},"publisher":"Nature Publishing Group","project":[{"_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","grant_number":"692692","call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse"},{"name":"Synaptic communication in neuronal microcircuits","_id":"25C5A090-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"Z00312"}],"volume":9},{"article_type":"original","month":"12","oa_version":"None","status":"public","issue":"4","quality_controlled":"1","doi":"10.1080/15257770.2018.1517883","author":[{"first_name":"S.","last_name":"Karthik","full_name":"Karthik, S."},{"first_name":"Pradeep K","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","orcid":"0000-0001-5996-956X","last_name":"Mandal","full_name":"Mandal, Pradeep K"},{"first_name":"A.","full_name":"Thirugnanasambandam, A.","last_name":"Thirugnanasambandam"},{"last_name":"Gautham","full_name":"Gautham, N.","first_name":"N."}],"day":"27","publisher":"Informa UK Limited","volume":38,"citation":{"apa":"Karthik, S., Mandal, P. K., Thirugnanasambandam, A., &#38; Gautham, N. (2018). Crystal structures of disordered Z-type helices. <i>Nucleosides, Nucleotides &#38;amp; Nucleic Acids</i>. Informa UK Limited. <a href=\"https://doi.org/10.1080/15257770.2018.1517883\">https://doi.org/10.1080/15257770.2018.1517883</a>","short":"S. Karthik, P.K. Mandal, A. Thirugnanasambandam, N. Gautham, Nucleosides, Nucleotides &#38;amp; Nucleic Acids 38 (2018) 279–293.","ista":"Karthik S, Mandal PK, Thirugnanasambandam A, Gautham N. 2018. Crystal structures of disordered Z-type helices. Nucleosides, Nucleotides &#38;amp; Nucleic Acids. 38(4), 279–293.","ama":"Karthik S, Mandal PK, Thirugnanasambandam A, Gautham N. Crystal structures of disordered Z-type helices. <i>Nucleosides, Nucleotides &#38;amp; Nucleic Acids</i>. 2018;38(4):279-293. doi:<a href=\"https://doi.org/10.1080/15257770.2018.1517883\">10.1080/15257770.2018.1517883</a>","mla":"Karthik, S., et al. “Crystal Structures of Disordered Z-Type Helices.” <i>Nucleosides, Nucleotides &#38;amp; Nucleic Acids</i>, vol. 38, no. 4, Informa UK Limited, 2018, pp. 279–93, doi:<a href=\"https://doi.org/10.1080/15257770.2018.1517883\">10.1080/15257770.2018.1517883</a>.","chicago":"Karthik, S., Pradeep K Mandal, A. Thirugnanasambandam, and N. Gautham. “Crystal Structures of Disordered Z-Type Helices.” <i>Nucleosides, Nucleotides &#38;amp; Nucleic Acids</i>. Informa UK Limited, 2018. <a href=\"https://doi.org/10.1080/15257770.2018.1517883\">https://doi.org/10.1080/15257770.2018.1517883</a>.","ieee":"S. Karthik, P. K. Mandal, A. Thirugnanasambandam, and N. Gautham, “Crystal structures of disordered Z-type helices,” <i>Nucleosides, Nucleotides &#38;amp; Nucleic Acids</i>, vol. 38, no. 4. Informa UK Limited, pp. 279–293, 2018."},"publication_status":"published","page":"279-293","intvolume":"        38","_id":"21094","type":"journal_article","has_accepted_license":"1","OA_type":"closed access","language":[{"iso":"eng"}],"article_processing_charge":"No","title":"Crystal structures of disordered Z-type helices","date_published":"2018-12-27T00:00:00Z","pmid":1,"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1532-2335"],"issn":["1525-7770"]},"year":"2018","date_updated":"2026-02-20T08:27:39Z","date_created":"2026-01-29T21:15:08Z","publication":"Nucleosides, Nucleotides &amp; Nucleic Acids","abstract":[{"lang":"eng","text":"The X-ray crystal structures of a decamer sequence d(CGCGTACGCG)2 and a tetradecamer sequence d(CGCGCGTACGCGCG)2 are presented here. Both sequences are alternating pyrimidine-purine repeat sequences and they form disordered, pseudo-continuous left handed Z-type helices. They demonstrate interesting variants of the ‘bundles of columns of helices’ mode of packing."}],"external_id":{"pmid":["30588873"]}},{"main_file_link":[{"url":"https://doi.org/10.1039/C8SC02966K","open_access":"1"}],"status":"public","issue":"1","month":"10","article_type":"original","oa_version":"Published Version","doi":"10.1039/c8sc02966k","quality_controlled":"1","OA_place":"publisher","license":"https://creativecommons.org/licenses/by-nc/3.0/","publisher":"Royal Society of Chemistry","volume":10,"author":[{"full_name":"Jeamet, Emeric","last_name":"Jeamet","first_name":"Emeric"},{"last_name":"Septavaux","full_name":"Septavaux, Jean","first_name":"Jean"},{"full_name":"Héloin, Alexandre","last_name":"Héloin","first_name":"Alexandre"},{"first_name":"Marion","full_name":"Donnier-Maréchal, Marion","last_name":"Donnier-Maréchal"},{"first_name":"Melissa","full_name":"Dumartin, Melissa","last_name":"Dumartin"},{"first_name":"Benjamin","full_name":"Ourri, Benjamin","last_name":"Ourri"},{"orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K","full_name":"Mandal, Pradeep K","last_name":"Mandal"},{"full_name":"Huc, Ivan","last_name":"Huc","first_name":"Ivan"},{"last_name":"Bignon","full_name":"Bignon, Emmanuelle","first_name":"Emmanuelle"},{"first_name":"Elise","full_name":"Dumont, Elise","last_name":"Dumont"},{"full_name":"Morell, Christophe","last_name":"Morell","first_name":"Christophe"},{"last_name":"Francoia","full_name":"Francoia, Jean-Patrick","first_name":"Jean-Patrick"},{"full_name":"Perret, Florent","last_name":"Perret","first_name":"Florent"},{"first_name":"Laurent","full_name":"Vial, Laurent","last_name":"Vial"},{"last_name":"Leclaire","full_name":"Leclaire, Julien","first_name":"Julien"}],"day":"08","DOAJ_listed":"1","citation":{"ieee":"E. Jeamet <i>et al.</i>, “Wetting the lock and key enthalpically favours polyelectrolyte binding,” <i>Chemical Science</i>, vol. 10, no. 1. Royal Society of Chemistry, pp. 277–283, 2018.","ista":"Jeamet E, Septavaux J, Héloin A, Donnier-Maréchal M, Dumartin M, Ourri B, Mandal PK, Huc I, Bignon E, Dumont E, Morell C, Francoia J-P, Perret F, Vial L, Leclaire J. 2018. Wetting the lock and key enthalpically favours polyelectrolyte binding. Chemical Science. 10(1), 277–283.","chicago":"Jeamet, Emeric, Jean Septavaux, Alexandre Héloin, Marion Donnier-Maréchal, Melissa Dumartin, Benjamin Ourri, Pradeep K Mandal, et al. “Wetting the Lock and Key Enthalpically Favours Polyelectrolyte Binding.” <i>Chemical Science</i>. Royal Society of Chemistry, 2018. <a href=\"https://doi.org/10.1039/c8sc02966k\">https://doi.org/10.1039/c8sc02966k</a>.","ama":"Jeamet E, Septavaux J, Héloin A, et al. Wetting the lock and key enthalpically favours polyelectrolyte binding. <i>Chemical Science</i>. 2018;10(1):277-283. doi:<a href=\"https://doi.org/10.1039/c8sc02966k\">10.1039/c8sc02966k</a>","mla":"Jeamet, Emeric, et al. “Wetting the Lock and Key Enthalpically Favours Polyelectrolyte Binding.” <i>Chemical Science</i>, vol. 10, no. 1, Royal Society of Chemistry, 2018, pp. 277–83, doi:<a href=\"https://doi.org/10.1039/c8sc02966k\">10.1039/c8sc02966k</a>.","apa":"Jeamet, E., Septavaux, J., Héloin, A., Donnier-Maréchal, M., Dumartin, M., Ourri, B., … Leclaire, J. (2018). Wetting the lock and key enthalpically favours polyelectrolyte binding. <i>Chemical Science</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/c8sc02966k\">https://doi.org/10.1039/c8sc02966k</a>","short":"E. Jeamet, J. Septavaux, A. Héloin, M. Donnier-Maréchal, M. Dumartin, B. Ourri, P.K. Mandal, I. Huc, E. Bignon, E. Dumont, C. Morell, J.-P. Francoia, F. Perret, L. Vial, J. Leclaire, Chemical Science 10 (2018) 277–283."},"publication_status":"published","page":"277-283","_id":"21096","type":"journal_article","has_accepted_license":"1","intvolume":"        10","title":"Wetting the lock and key enthalpically favours polyelectrolyte binding","article_processing_charge":"No","tmp":{"name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)","short":"CC BY-NC (3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","image":"/images/cc_by_nc.png"},"date_published":"2018-10-08T00:00:00Z","OA_type":"gold","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"extern":"1","abstract":[{"lang":"eng","text":"By using a combination of readily accessible experimental and computational experiments in water, we explored the factors governing the association between polyanionic dyn[4]arene and a series of α,ω-alkyldiammonium ions of increasing chain length. We found that the lock-and-key concept based on the best match between the apolar and polar regions of the molecular partners failed to explain the observed selectivities. Instead, the dissection of the energetic and structural contributions demonstrated that the binding events were actually guided by two crucial solvent-related phenomena as the chain length of the guest increases: the expected decrease of the enthalpic cost of guest desolvation and the unexpected increase of the favourable enthalpy of complex solvation. By bringing to light the decisive enthalpic impact of complex solvation during the binding of polyelectrolytes by inclusion, this study may provide a missing piece to a puzzle that one day could display the global picture of molecular recognition in water."}],"publication_identifier":{"issn":["2041-6520"],"eissn":["2041-6539"]},"publication":"Chemical Science","date_created":"2026-01-29T21:20:24Z","year":"2018","date_updated":"2026-02-23T10:00:16Z"},{"intvolume":"        10","has_accepted_license":"1","type":"journal_article","_id":"21097","language":[{"iso":"eng"}],"OA_type":"closed access","pmid":1,"date_published":"2018-03-19T00:00:00Z","article_processing_charge":"No","title":"Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Nature Chemistry","date_created":"2026-01-29T21:27:38Z","year":"2018","date_updated":"2026-02-20T08:58:10Z","publication_identifier":{"issn":["1755-4330"],"eissn":["1755-4349"]},"external_id":{"pmid":["29556052"]},"abstract":[{"lang":"eng","text":"Translation, the mRNA-templated synthesis of peptides by the ribosome, can be manipulated to incorporate variants of the 20 cognate amino acids. Such approaches for expanding the range of chemical entities that can be produced by the ribosome may accelerate the discovery of molecules that can perform functions for which poorly folded, short peptidic sequences are ill suited. Here, we show that the ribosome tolerates some artificial helical aromatic oligomers, so-called foldamers. Using a flexible tRNA-acylation ribozyme—flexizyme—foldamers were attached to tRNA, and the resulting acylated tRNAs were delivered to the ribosome to initiate the synthesis of non-cyclic and cyclic foldamer–peptide hybrid molecules. Passing through the ribosome exit tunnel requires the foldamers to unfold. Yet foldamers encode sufficient folding information to influence the peptide structure once translation is completed. We also show that in cyclic hybrids, the foldamer portion can fold into a helix and force the peptide segment to adopt a constrained and stretched conformation."}],"oa_version":"None","month":"03","article_type":"original","issue":"4","status":"public","quality_controlled":"1","doi":"10.1038/s41557-018-0007-x","day":"19","related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/s41557-018-0086-8"}]},"author":[{"first_name":"Joseph M.","full_name":"Rogers, Joseph M.","last_name":"Rogers"},{"first_name":"Sunbum","full_name":"Kwon, Sunbum","last_name":"Kwon"},{"last_name":"Dawson","full_name":"Dawson, Simon J.","first_name":"Simon J."},{"orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K","full_name":"Mandal, Pradeep K","last_name":"Mandal"},{"full_name":"Suga, Hiroaki","last_name":"Suga","first_name":"Hiroaki"},{"full_name":"Huc, Ivan","last_name":"Huc","first_name":"Ivan"}],"volume":10,"publisher":"Springer Nature","page":"405-412","publication_status":"published","citation":{"ieee":"J. M. Rogers, S. Kwon, S. J. Dawson, P. K. Mandal, H. Suga, and I. Huc, “Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids,” <i>Nature Chemistry</i>, vol. 10, no. 4. Springer Nature, pp. 405–412, 2018.","apa":"Rogers, J. M., Kwon, S., Dawson, S. J., Mandal, P. K., Suga, H., &#38; Huc, I. (2018). Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. <i>Nature Chemistry</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41557-018-0007-x\">https://doi.org/10.1038/s41557-018-0007-x</a>","short":"J.M. Rogers, S. Kwon, S.J. Dawson, P.K. Mandal, H. Suga, I. Huc, Nature Chemistry 10 (2018) 405–412.","mla":"Rogers, Joseph M., et al. “Ribosomal Synthesis and Folding of Peptide-Helical Aromatic Foldamer Hybrids.” <i>Nature Chemistry</i>, vol. 10, no. 4, Springer Nature, 2018, pp. 405–12, doi:<a href=\"https://doi.org/10.1038/s41557-018-0007-x\">10.1038/s41557-018-0007-x</a>.","ama":"Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I. Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. <i>Nature Chemistry</i>. 2018;10(4):405-412. doi:<a href=\"https://doi.org/10.1038/s41557-018-0007-x\">10.1038/s41557-018-0007-x</a>","chicago":"Rogers, Joseph M., Sunbum Kwon, Simon J. Dawson, Pradeep K Mandal, Hiroaki Suga, and Ivan Huc. “Ribosomal Synthesis and Folding of Peptide-Helical Aromatic Foldamer Hybrids.” <i>Nature Chemistry</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41557-018-0007-x\">https://doi.org/10.1038/s41557-018-0007-x</a>.","ista":"Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I. 2018. Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. Nature Chemistry. 10(4), 405–412."}},{"external_id":{"pmid":["30120882"]},"abstract":[{"text":"Phospholipase A2 (PLA2) is one of the rate limiting enzymes involved in the production of arachidonic acid, a potent inflammatory mediator. PLA2 is widely distributed all over the animal kingdom. It is also seen in inflammatory exudation and venoms of different organisms. The studies demonstrated that PLA2 inhibitors have broad spectrum activities that they can either be used against inflammation or envenomation. In this study, the inhibitory activity of 1-napthaleneacetic acid (NAA) against porcine pancreatic PLA2 has been explained through isothermal titration calorimetry and enzyme kinetics studies. The atomic level of interactions of NAA with PLA2 was also studied using X-ray crystallography. Apart from these findings, the theoretical binding affinities and mode of interactions of two naphthalene-based NSAIDs such as naproxen (NAP) and nabumetone (NAB) were studied through molecular modeling. The studies proved that the selected ligands are binding at the doorway of the active site cleft and hindering the substrate entry to the active site. The study brings out a potential scaffold for the designing of broad spectrum PLA2 inhibitors which can be used for inflammation or envenomation. ","lang":"eng"}],"publication":"IUBMB Life","date_created":"2026-02-06T12:12:20Z","year":"2018","date_updated":"2026-02-20T08:09:53Z","publication_identifier":{"issn":["1521-6543"],"eissn":["1521-6551"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","pmid":1,"date_published":"2018-10-01T00:00:00Z","article_processing_charge":"No","title":"Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid","language":[{"iso":"eng"}],"OA_type":"closed access","has_accepted_license":"1","_id":"21152","type":"journal_article","intvolume":"        70","publication_status":"published","page":"995-1001","citation":{"ama":"Dileep KV, Remya C, Tintu I, et al. Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid. <i>IUBMB Life</i>. 2018;70(10):995-1001. doi:<a href=\"https://doi.org/10.1002/iub.1924\">10.1002/iub.1924</a>","chicago":"Dileep, Kalarickal V., Chandran Remya, Ignatius Tintu, Pradeep K Mandal, Ponnuraj Karthe, Madathilkovilakathu Haridas, and Chittalakkottu Sadasivan. “Crystal Structure of Phospholipase A2 in Complex with 1‐naphthaleneacetic Acid.” <i>IUBMB Life</i>. Wiley, 2018. <a href=\"https://doi.org/10.1002/iub.1924\">https://doi.org/10.1002/iub.1924</a>.","ista":"Dileep KV, Remya C, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C. 2018. Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid. IUBMB Life. 70(10), 995–1001.","mla":"Dileep, Kalarickal V., et al. “Crystal Structure of Phospholipase A2 in Complex with 1‐naphthaleneacetic Acid.” <i>IUBMB Life</i>, vol. 70, no. 10, Wiley, 2018, pp. 995–1001, doi:<a href=\"https://doi.org/10.1002/iub.1924\">10.1002/iub.1924</a>.","apa":"Dileep, K. V., Remya, C., Tintu, I., Mandal, P. K., Karthe, P., Haridas, M., &#38; Sadasivan, C. (2018). Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid. <i>IUBMB Life</i>. Wiley. <a href=\"https://doi.org/10.1002/iub.1924\">https://doi.org/10.1002/iub.1924</a>","short":"K.V. Dileep, C. Remya, I. Tintu, P.K. Mandal, P. Karthe, M. Haridas, C. Sadasivan, IUBMB Life 70 (2018) 995–1001.","ieee":"K. V. Dileep <i>et al.</i>, “Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid,” <i>IUBMB Life</i>, vol. 70, no. 10. Wiley, pp. 995–1001, 2018."},"volume":70,"publisher":"Wiley","day":"01","author":[{"full_name":"Dileep, Kalarickal V.","last_name":"Dileep","first_name":"Kalarickal V."},{"first_name":"Chandran","last_name":"Remya","full_name":"Remya, Chandran"},{"last_name":"Tintu","full_name":"Tintu, Ignatius","first_name":"Ignatius"},{"full_name":"Mandal, Pradeep K","last_name":"Mandal","orcid":"0000-0001-5996-956X","id":"6a3def15-d4b4-11ef-9fa9-a24c1f545ec3","first_name":"Pradeep K"},{"first_name":"Ponnuraj","full_name":"Karthe, Ponnuraj","last_name":"Karthe"},{"full_name":"Haridas, Madathilkovilakathu","last_name":"Haridas","first_name":"Madathilkovilakathu"},{"first_name":"Chittalakkottu","full_name":"Sadasivan, Chittalakkottu","last_name":"Sadasivan"}],"doi":"10.1002/iub.1924","quality_controlled":"1","issue":"10","status":"public","oa_version":"None","month":"10","article_type":"original"},{"article_type":"letter_note","month":"02","oa_version":"None","status":"public","keyword":["Metasurface","dispersion engineering","visible spectrum","titanium dioxide","orbital angular momentum states","achromatic metalens"],"issue":"4","quality_controlled":"1","doi":"10.1021/acs.nanolett.7b05458","author":[{"last_name":"Shi","full_name":"Shi, Zhujun","first_name":"Zhujun"},{"first_name":"Mohammadreza","last_name":"Khorasaninejad","full_name":"Khorasaninejad, Mohammadreza"},{"first_name":"Yao-Wei","full_name":"Huang, Yao-Wei","last_name":"Huang"},{"full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","first_name":"Charles"},{"full_name":"Zhu, Alexander Y.","last_name":"Zhu","first_name":"Alexander Y."},{"full_name":"Chen, Wei Ting","last_name":"Chen","first_name":"Wei Ting"},{"first_name":"Vyshakh","full_name":"Sanjeev, Vyshakh","last_name":"Sanjeev"},{"last_name":"Ding","full_name":"Ding, Zhao-Wei","first_name":"Zhao-Wei"},{"first_name":"Michele","full_name":"Tamagnone, Michele","last_name":"Tamagnone"},{"first_name":"Kundan","last_name":"Chaudhary","full_name":"Chaudhary, Kundan"},{"first_name":"Robert C.","last_name":"Devlin","full_name":"Devlin, Robert C."},{"first_name":"Cheng-Wei","full_name":"Qiu, Cheng-Wei","last_name":"Qiu"},{"last_name":"Capasso","full_name":"Capasso, Federico","first_name":"Federico"}],"day":"20","publisher":"American Chemical Society ","volume":18,"citation":{"ieee":"Z. Shi <i>et al.</i>, “Single-layer metasurface with controllable multiwavelength functions,” <i>Nano Letters</i>, vol. 18, no. 4. American Chemical Society , pp. 2420–2427, 2018.","ama":"Shi Z, Khorasaninejad M, Huang Y-W, et al. Single-layer metasurface with controllable multiwavelength functions. <i>Nano Letters</i>. 2018;18(4):2420-2427. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.7b05458\">10.1021/acs.nanolett.7b05458</a>","ista":"Shi Z, Khorasaninejad M, Huang Y-W, Roques-Carmes C, Zhu AY, Chen WT, Sanjeev V, Ding Z-W, Tamagnone M, Chaudhary K, Devlin RC, Qiu C-W, Capasso F. 2018. Single-layer metasurface with controllable multiwavelength functions. Nano Letters. 18(4), 2420–2427.","mla":"Shi, Zhujun, et al. “Single-Layer Metasurface with Controllable Multiwavelength Functions.” <i>Nano Letters</i>, vol. 18, no. 4, American Chemical Society , 2018, pp. 2420–27, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.7b05458\">10.1021/acs.nanolett.7b05458</a>.","chicago":"Shi, Zhujun, Mohammadreza Khorasaninejad, Yao-Wei Huang, Charles Roques-Carmes, Alexander Y. Zhu, Wei Ting Chen, Vyshakh Sanjeev, et al. “Single-Layer Metasurface with Controllable Multiwavelength Functions.” <i>Nano Letters</i>. American Chemical Society , 2018. <a href=\"https://doi.org/10.1021/acs.nanolett.7b05458\">https://doi.org/10.1021/acs.nanolett.7b05458</a>.","short":"Z. Shi, M. Khorasaninejad, Y.-W. Huang, C. Roques-Carmes, A.Y. Zhu, W.T. Chen, V. Sanjeev, Z.-W. Ding, M. Tamagnone, K. Chaudhary, R.C. Devlin, C.-W. Qiu, F. Capasso, Nano Letters 18 (2018) 2420–2427.","apa":"Shi, Z., Khorasaninejad, M., Huang, Y.-W., Roques-Carmes, C., Zhu, A. Y., Chen, W. T., … Capasso, F. (2018). Single-layer metasurface with controllable multiwavelength functions. <i>Nano Letters</i>. American Chemical Society . <a href=\"https://doi.org/10.1021/acs.nanolett.7b05458\">https://doi.org/10.1021/acs.nanolett.7b05458</a>"},"page":"2420-2427","publication_status":"published","scopus_import":"1","intvolume":"        18","type":"journal_article","_id":"21523","OA_type":"closed access","language":[{"iso":"eng"}],"title":"Single-layer metasurface with controllable multiwavelength functions","article_processing_charge":"No","date_published":"2018-02-20T00:00:00Z","pmid":1,"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1530-6992"],"issn":["1530-6984"]},"date_updated":"2026-04-15T07:52:46Z","year":"2018","publication":"Nano Letters","date_created":"2026-03-30T12:22:47Z","abstract":[{"text":"In this paper, we report dispersion-engineered metasurfaces with distinct functionalities controlled by wavelength. Unlike previous approaches based on spatial multiplexing or vertical stacking of metasurfaces, we utilize a single phase profile with wavelength dependence encoded in the phase shifters’ dispersion. We designed and fabricated a multiwavelength achromatic metalens (MAM) with achromatic focusing for blue (B), green (G), yellow (Y), and red (R) light and two wavelength-controlled beam generators (WCBG): one focuses light with orbital angular momentum (OAM) states (l = 0,1,2) corresponding to three primary colors; the other produces ordinary focal spots (l = 0) for red and green light, while generating a vortex beam (l = 1) in the blue. A full color (RGB) hologram is also demonstrated in simulation. Our approach opens a path to applications ranging from near-eye displays and holography to compact multiwavelength beam generation.","lang":"eng"}],"external_id":{"pmid":["29461838"]}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"extern":"1","external_id":{"arxiv":["1710.05358"]},"abstract":[{"lang":"eng","text":"Recent advances in the fabrication of nanostructures and nanoscale features in metasurfaces offer new prospects for generating visible light emission from low-energy electrons. Here we present the experimental observation of visible light emission from low-energy free electrons interacting with nanoscale periodic surfaces through the Smith–Purcell (SP) effect. We demonstrate SP light emission from nanoscale gratings with periodicity as small as 50 nm, enabling the observation of tunable visible radiation from low-energy electrons (1.5 to 6 keV), an order of magnitude lower in energy than previously reported. We study the emission wavelength and intensity dependence on the grating pitch and electron energy, showing agreement between experiment and theory. Our results open the way to the production of SP-based nanophotonics integrated devices. Built inside electron microscopes, SP sources could enable the development of novel electron–optical correlated spectroscopic techniques and facilitate the observation of new quantum effects in light sources."}],"date_created":"2026-03-30T12:22:47Z","publication":"ACS Photonics","year":"2018","date_updated":"2026-04-15T11:48:45Z","arxiv":1,"publication_identifier":{"eissn":["2330-4022"]},"_id":"21533","type":"journal_article","intvolume":"         5","date_published":"2018-08-30T00:00:00Z","article_processing_charge":"No","title":"Smith–Purcell radiation from low-energy electrons","language":[{"iso":"eng"}],"OA_type":"green","volume":5,"publisher":"American Chemical Society ","day":"30","author":[{"last_name":"Massuda","full_name":"Massuda, Aviram","first_name":"Aviram"},{"id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","first_name":"Charles","last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles"},{"first_name":"Yujia","full_name":"Yang, Yujia","last_name":"Yang"},{"last_name":"Kooi","full_name":"Kooi, Steven E.","first_name":"Steven E."},{"first_name":"Yi","last_name":"Yang","full_name":"Yang, Yi"},{"first_name":"Chitraang","full_name":"Murdia, Chitraang","last_name":"Murdia"},{"full_name":"Berggren, Karl K.","last_name":"Berggren","first_name":"Karl K."},{"full_name":"Kaminer, Ido","last_name":"Kaminer","first_name":"Ido"},{"last_name":"Soljačić","full_name":"Soljačić, Marin","first_name":"Marin"}],"scopus_import":"1","page":"3513-3518","publication_status":"published","citation":{"ieee":"A. Massuda <i>et al.</i>, “Smith–Purcell radiation from low-energy electrons,” <i>ACS Photonics</i>, vol. 5, no. 9. American Chemical Society , pp. 3513–3518, 2018.","ista":"Massuda A, Roques-Carmes C, Yang Y, Kooi SE, Yang Y, Murdia C, Berggren KK, Kaminer I, Soljačić M. 2018. Smith–Purcell radiation from low-energy electrons. ACS Photonics. 5(9), 3513–3518.","mla":"Massuda, Aviram, et al. “Smith–Purcell Radiation from Low-Energy Electrons.” <i>ACS Photonics</i>, vol. 5, no. 9, American Chemical Society , 2018, pp. 3513–18, doi:<a href=\"https://doi.org/10.1021/acsphotonics.8b00743\">10.1021/acsphotonics.8b00743</a>.","ama":"Massuda A, Roques-Carmes C, Yang Y, et al. Smith–Purcell radiation from low-energy electrons. <i>ACS Photonics</i>. 2018;5(9):3513-3518. doi:<a href=\"https://doi.org/10.1021/acsphotonics.8b00743\">10.1021/acsphotonics.8b00743</a>","chicago":"Massuda, Aviram, Charles Roques-Carmes, Yujia Yang, Steven E. Kooi, Yi Yang, Chitraang Murdia, Karl K. Berggren, Ido Kaminer, and Marin Soljačić. “Smith–Purcell Radiation from Low-Energy Electrons.” <i>ACS Photonics</i>. American Chemical Society , 2018. <a href=\"https://doi.org/10.1021/acsphotonics.8b00743\">https://doi.org/10.1021/acsphotonics.8b00743</a>.","apa":"Massuda, A., Roques-Carmes, C., Yang, Y., Kooi, S. E., Yang, Y., Murdia, C., … Soljačić, M. (2018). Smith–Purcell radiation from low-energy electrons. <i>ACS Photonics</i>. American Chemical Society . <a href=\"https://doi.org/10.1021/acsphotonics.8b00743\">https://doi.org/10.1021/acsphotonics.8b00743</a>","short":"A. Massuda, C. Roques-Carmes, Y. Yang, S.E. Kooi, Y. Yang, C. Murdia, K.K. Berggren, I. Kaminer, M. Soljačić, ACS Photonics 5 (2018) 3513–3518."},"ddc":["530"],"issue":"9","keyword":["light−matter interactions","periodic structures","nanophotonics","free-electron light sources"],"status":"public","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1710.05358","open_access":"1"}],"oa_version":"Preprint","month":"08","article_type":"letter_note","doi":"10.1021/acsphotonics.8b00743","quality_controlled":"1","OA_place":"repository"},{"intvolume":"        14","type":"journal_article","_id":"21545","OA_type":"green","language":[{"iso":"eng"}],"title":"Maximal spontaneous photon emission and energy loss from free electrons","article_processing_charge":"No","date_published":"2018-09-01T00:00:00Z","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"arxiv":1,"publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"publication":"Nature Physics","date_created":"2026-03-30T12:22:47Z","year":"2018","date_updated":"2026-04-15T12:22:56Z","abstract":[{"text":"Free-electron radiation such as Cerenkov1, Smith–Purcell2 and transition radiation3,4 can be greatly affected by structured optical environments, as has been demonstrated in a variety of polaritonic5,6, photonic-crystal7 and metamaterial8,9,10 systems. However, the amount of radiation that can ultimately be extracted from free electrons near an arbitrary material structure has remained elusive. Here we derive a fundamental upper limit to the spontaneous photon emission and energy loss of free electrons, regardless of geometry, which illuminates the effects of material properties and electron velocities. We obtain experimental evidence for our theory with quantitative measurements of Smith–Purcell radiation. Our framework allows us to make two predictions. One is a new regime of radiation operation—at subwavelength separations, slower (non-relativistic) electrons can achieve stronger radiation than fast (relativistic) electrons. The other is a divergence of the emission probability in the limit of lossless materials. We further reveal that such divergences can be approached by coupling free electrons to photonic bound states in the continuum11,12,13. Our findings suggest that compact and efficient free-electron radiation sources from microwaves to the soft X-ray regime may be achievable without requiring ultrahigh accelerating voltages.","lang":"eng"}],"external_id":{"arxiv":["1901.06593"]},"month":"09","article_type":"letter_note","oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.1901.06593","open_access":"1"}],"status":"public","OA_place":"repository","doi":"10.1038/s41567-018-0180-2","quality_controlled":"1","author":[{"first_name":"Yi","full_name":"Yang, Yi","last_name":"Yang"},{"last_name":"Massuda","full_name":"Massuda, Aviram","first_name":"Aviram"},{"last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82"},{"first_name":"Steven E.","last_name":"Kooi","full_name":"Kooi, Steven E."},{"full_name":"Christensen, Thomas","last_name":"Christensen","first_name":"Thomas"},{"last_name":"Johnson","full_name":"Johnson, Steven G.","first_name":"Steven G."},{"first_name":"John D.","full_name":"Joannopoulos, John D.","last_name":"Joannopoulos"},{"full_name":"Miller, Owen D.","last_name":"Miller","first_name":"Owen D."},{"full_name":"Kaminer, Ido","last_name":"Kaminer","first_name":"Ido"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"day":"01","related_material":{"link":[{"relation":"erratum","url":"https://doi.org/10.1038/s41567-018-0252-3"}]},"publisher":"Springer Nature","volume":14,"citation":{"ieee":"Y. Yang <i>et al.</i>, “Maximal spontaneous photon emission and energy loss from free electrons,” <i>Nature Physics</i>, vol. 14. Springer Nature, pp. 894–899, 2018.","chicago":"Yang, Yi, Aviram Massuda, Charles Roques-Carmes, Steven E. Kooi, Thomas Christensen, Steven G. Johnson, John D. Joannopoulos, Owen D. Miller, Ido Kaminer, and Marin Soljačić. “Maximal Spontaneous Photon Emission and Energy Loss from Free Electrons.” <i>Nature Physics</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41567-018-0180-2\">https://doi.org/10.1038/s41567-018-0180-2</a>.","ama":"Yang Y, Massuda A, Roques-Carmes C, et al. Maximal spontaneous photon emission and energy loss from free electrons. <i>Nature Physics</i>. 2018;14:894-899. doi:<a href=\"https://doi.org/10.1038/s41567-018-0180-2\">10.1038/s41567-018-0180-2</a>","mla":"Yang, Yi, et al. “Maximal Spontaneous Photon Emission and Energy Loss from Free Electrons.” <i>Nature Physics</i>, vol. 14, Springer Nature, 2018, pp. 894–99, doi:<a href=\"https://doi.org/10.1038/s41567-018-0180-2\">10.1038/s41567-018-0180-2</a>.","ista":"Yang Y, Massuda A, Roques-Carmes C, Kooi SE, Christensen T, Johnson SG, Joannopoulos JD, Miller OD, Kaminer I, Soljačić M. 2018. Maximal spontaneous photon emission and energy loss from free electrons. Nature Physics. 14, 894–899.","short":"Y. Yang, A. Massuda, C. Roques-Carmes, S.E. Kooi, T. Christensen, S.G. Johnson, J.D. Joannopoulos, O.D. Miller, I. Kaminer, M. Soljačić, Nature Physics 14 (2018) 894–899.","apa":"Yang, Y., Massuda, A., Roques-Carmes, C., Kooi, S. E., Christensen, T., Johnson, S. G., … Soljačić, M. (2018). Maximal spontaneous photon emission and energy loss from free electrons. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-018-0180-2\">https://doi.org/10.1038/s41567-018-0180-2</a>"},"page":"894-899","publication_status":"published","scopus_import":"1"},{"intvolume":"         8","_id":"21563","type":"journal_article","has_accepted_license":"1","OA_type":"gold","language":[{"iso":"eng"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Nonperturbative quantum electrodynamics in the Cherenkov effect","article_processing_charge":"Yes","date_published":"2018-10-17T00:00:00Z","extern":"1","oa":1,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publication_identifier":{"eissn":["2160-3308"]},"date_updated":"2026-04-13T13:28:00Z","year":"2018","publication":"Physical Review X","date_created":"2026-03-30T12:22:47Z","abstract":[{"text":"Quantum electrodynamics (QED) is one of the most precisely tested theories in the history of science, giving accurate predictions to a wide range of experimental observations. Recent experimental advances allow for the ability to probe physics on extremely short attosecond timescales, enabling ultrafast imaging of quantum dynamics. It is of great interest to extend our understanding of short-time quantum dynamics to QED, where the focus is typically on long-time observables such as 𝑆\r\nmatrices, decay rates, and cross sections. That said, solving the short-time dynamics of the QED Hamiltonian can lead to divergences, making it unclear how to arrive at physical predictions. We present an approach to regularize QED at short times and apply it to the problem of free-electron radiation into a medium, known as Cherenkov radiation. Our regularization method, which can be extended to other QED processes, is performed by subtracting the self-energy in free space from the self-energy calculated in the medium. Surprisingly, we find a number of previously unknown phenomena yielding corrections to the conventional Cherenkov effect that could be observed in current experiments. Specifically, the Cherenkov velocity threshold increases relative to the famous conventional theory. This modification to the conventional theory, which can be non-negligible in realistic scenarios, should result in the suppression of spontaneous emission in readily available experiments. Finally, we reveal a bifurcation process creating radiation into new Cherenkov angles, occurring in the strong-coupling regime, which would be realizable by considering the radiation dynamics of highly charged ions. Our results shed light on QED phenomena at short times and reveal surprising new physics in the Cherenkov effect.","lang":"eng"}],"article_type":"original","month":"10","oa_version":"Published Version","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1103/PhysRevX.8.041013"}],"article_number":"041013","issue":"4","ddc":["530"],"OA_place":"publisher","quality_controlled":"1","doi":"10.1103/physrevx.8.041013","author":[{"first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles"},{"full_name":"Rivera, Nicholas","last_name":"Rivera","first_name":"Nicholas"},{"first_name":"John D.","full_name":"Joannopoulos, John D.","last_name":"Joannopoulos"},{"first_name":"Marin","full_name":"Soljačić, Marin","last_name":"Soljačić"},{"last_name":"Kaminer","full_name":"Kaminer, Ido","first_name":"Ido"}],"day":"17","publisher":"American Physical Society","volume":8,"citation":{"apa":"Roques-Carmes, C., Rivera, N., Joannopoulos, J. D., Soljačić, M., &#38; Kaminer, I. (2018). Nonperturbative quantum electrodynamics in the Cherenkov effect. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevx.8.041013\">https://doi.org/10.1103/physrevx.8.041013</a>","short":"C. Roques-Carmes, N. Rivera, J.D. Joannopoulos, M. Soljačić, I. Kaminer, Physical Review X 8 (2018).","ama":"Roques-Carmes C, Rivera N, Joannopoulos JD, Soljačić M, Kaminer I. Nonperturbative quantum electrodynamics in the Cherenkov effect. <i>Physical Review X</i>. 2018;8(4). doi:<a href=\"https://doi.org/10.1103/physrevx.8.041013\">10.1103/physrevx.8.041013</a>","mla":"Roques-Carmes, Charles, et al. “Nonperturbative Quantum Electrodynamics in the Cherenkov Effect.” <i>Physical Review X</i>, vol. 8, no. 4, 041013, American Physical Society, 2018, doi:<a href=\"https://doi.org/10.1103/physrevx.8.041013\">10.1103/physrevx.8.041013</a>.","ista":"Roques-Carmes C, Rivera N, Joannopoulos JD, Soljačić M, Kaminer I. 2018. Nonperturbative quantum electrodynamics in the Cherenkov effect. Physical Review X. 8(4), 041013.","chicago":"Roques-Carmes, Charles, Nicholas Rivera, John D. Joannopoulos, Marin Soljačić, and Ido Kaminer. “Nonperturbative Quantum Electrodynamics in the Cherenkov Effect.” <i>Physical Review X</i>. American Physical Society, 2018. <a href=\"https://doi.org/10.1103/physrevx.8.041013\">https://doi.org/10.1103/physrevx.8.041013</a>.","ieee":"C. Roques-Carmes, N. Rivera, J. D. Joannopoulos, M. Soljačić, and I. Kaminer, “Nonperturbative quantum electrodynamics in the Cherenkov effect,” <i>Physical Review X</i>, vol. 8, no. 4. American Physical Society, 2018."},"publication_status":"published","DOAJ_listed":"1","scopus_import":"1"},{"article_processing_charge":"No","title":"Substrate aberration and correction for meta-lens imaging: An analytical approach","pmid":1,"date_published":"2018-04-12T00:00:00Z","OA_type":"closed access","language":[{"iso":"eng"}],"_id":"21587","type":"journal_article","intvolume":"        57","abstract":[{"lang":"eng","text":"Meta-lenses based on flat optics enabled a fundamental shift in lens production—providing an easier manufacturing process with an increase in lens profile precision and a reduction in size and weight. Here we present an analytical approach to correct spherical aberrations caused by light propagation through the substrate by adding a substrate-corrected phase profile, which differs from the original hyperbolic one. A meta-lens encoding the new phase profile would yield diffraction-limited focusing and an increase of up to 0.3 of its numerical aperture without changing the radius or focal length. In tightly focused laser spot applications such as direct laser lithography and laser printing, a substrate-corrected meta-lens can reduce the spatial footprint of the meta-lens."}],"external_id":{"pmid":[" 29714325"]},"publication_identifier":{"eissn":["2155-3165"],"issn":["1559-128X"]},"publication":"Applied Optics","date_created":"2026-03-30T12:22:48Z","year":"2018","date_updated":"2026-04-27T08:41:20Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","extern":"1","quality_controlled":"1","doi":"10.1364/ao.57.002973","status":"public","issue":"12","ddc":["530"],"month":"04","article_type":"original","oa_version":"None","scopus_import":"1","citation":{"ista":"Groever B, Roques-Carmes C, Byrnes SJ, Capasso F. 2018. Substrate aberration and correction for meta-lens imaging: An analytical approach. Applied Optics. 57(12), 2973–2980.","ama":"Groever B, Roques-Carmes C, Byrnes SJ, Capasso F. Substrate aberration and correction for meta-lens imaging: An analytical approach. <i>Applied Optics</i>. 2018;57(12):2973-2980. doi:<a href=\"https://doi.org/10.1364/ao.57.002973\">10.1364/ao.57.002973</a>","chicago":"Groever, Benedikt, Charles Roques-Carmes, Steven J. Byrnes, and Federico Capasso. “Substrate Aberration and Correction for Meta-Lens Imaging: An Analytical Approach.” <i>Applied Optics</i>. Optica Publishing Group, 2018. <a href=\"https://doi.org/10.1364/ao.57.002973\">https://doi.org/10.1364/ao.57.002973</a>.","mla":"Groever, Benedikt, et al. “Substrate Aberration and Correction for Meta-Lens Imaging: An Analytical Approach.” <i>Applied Optics</i>, vol. 57, no. 12, Optica Publishing Group, 2018, pp. 2973–80, doi:<a href=\"https://doi.org/10.1364/ao.57.002973\">10.1364/ao.57.002973</a>.","apa":"Groever, B., Roques-Carmes, C., Byrnes, S. J., &#38; Capasso, F. (2018). Substrate aberration and correction for meta-lens imaging: An analytical approach. <i>Applied Optics</i>. Optica Publishing Group. <a href=\"https://doi.org/10.1364/ao.57.002973\">https://doi.org/10.1364/ao.57.002973</a>","short":"B. Groever, C. Roques-Carmes, S.J. Byrnes, F. Capasso, Applied Optics 57 (2018) 2973–2980.","ieee":"B. Groever, C. Roques-Carmes, S. J. Byrnes, and F. Capasso, “Substrate aberration and correction for meta-lens imaging: An analytical approach,” <i>Applied Optics</i>, vol. 57, no. 12. Optica Publishing Group, pp. 2973–2980, 2018."},"publication_status":"published","page":"2973-2980","publisher":"Optica Publishing Group","volume":57,"author":[{"first_name":"Benedikt","last_name":"Groever","full_name":"Groever, Benedikt"},{"last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","first_name":"Charles"},{"first_name":"Steven J.","last_name":"Byrnes","full_name":"Byrnes, Steven J."},{"first_name":"Federico","last_name":"Capasso","full_name":"Capasso, Federico"}],"day":"12"}]