[{"OA_type":"gold","date_created":"2023-09-01T11:32:02Z","oa":1,"quality_controlled":"1","volume":5,"article_processing_charge":"Yes","file_date_updated":"2024-01-30T12:59:57Z","article_type":"original","publisher":"Elsevier","ddc":["580"],"article_number":"100669","month":"01","abstract":[{"lang":"eng","text":"The phytohormone auxin and its directional transport through tissues play a fundamental role in development of higher plants. This polar auxin transport predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization is crucial for development, but its evolution during the rise of morphological complexity in land plants remains unclear. Here, we performed a cross-species investigation by observing the trafficking and localization of endogenous and exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha, and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion did not compromise the auxin export function of all examined PINs by using radioactive auxin export assay and by observing the phenotypic changes in transgenic bryophytes. Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root epidermis, bryophytic PINs show no defined polarity. Pharmacological interference revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN polarization. The divergence of PIN polarization and trafficking is also observed within the bryophyte clade and between tissues of individual species. These results collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity mechanisms."}],"status":"public","publication_identifier":{"issn":["2590-3462"]},"DOAJ_listed":"1","ec_funded":1,"publication":"Plant Communications","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"This work was supported by the ERC grant (PR1023ERC02) to H. T. and J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001) to K. J. L.","isi":1,"issue":"1","date_published":"2024-01-08T00:00:00Z","date_updated":"2025-08-05T13:27:26Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"pmid":["37528584"],"isi":["001158054500001"]},"file":[{"file_id":"14911","success":1,"date_created":"2024-01-30T12:59:57Z","creator":"dernst","access_level":"open_access","file_size":2825565,"content_type":"application/pdf","file_name":"2023_PlantCommunications_Tang.pdf","checksum":"edbc44c6d4a394d2bf70f92fdbb08f0a","date_updated":"2024-01-30T12:59:57Z","relation":"main_file"}],"year":"2024","day":"08","pmid":1,"doi":"10.1016/j.xplc.2023.100669","title":"Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution","publication_status":"published","citation":{"apa":"Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., & Friml, J. (2024). Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. Elsevier. https://doi.org/10.1016/j.xplc.2023.100669","ieee":"H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution,” Plant Communications, vol. 5, no. 1. Elsevier, 2024.","ama":"Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 2024;5(1). doi:10.1016/j.xplc.2023.100669","mla":"Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications, vol. 5, no. 1, 100669, Elsevier, 2024, doi:10.1016/j.xplc.2023.100669.","ista":"Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking and polarization mechanisms for PIN auxin transporters during land plant evolution. Plant Communications. 5(1), 100669.","chicago":"Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land Plant Evolution.” Plant Communications. Elsevier, 2024. https://doi.org/10.1016/j.xplc.2023.100669.","short":"H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications 5 (2024)."},"author":[{"orcid":"0000-0001-6152-6637","full_name":"Tang, Han","first_name":"Han","last_name":"Tang","id":"19BDF720-25A0-11EA-AC6E-928F3DDC885E"},{"full_name":"Lu, KJ","last_name":"Lu","first_name":"KJ"},{"last_name":"Zhang","first_name":"Y","full_name":"Zhang, Y"},{"first_name":"YL","last_name":"Cheng","full_name":"Cheng, YL"},{"last_name":"Tu","first_name":"SL","full_name":"Tu, SL"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří"}],"OA_place":"publisher","corr_author":"1","project":[{"_id":"261099A6-B435-11E9-9278-68D0E5697425","name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","grant_number":"742985"}],"intvolume":" 5","department":[{"_id":"JiFr"}],"_id":"14251","oa_version":"Published Version","type":"journal_article"},{"citation":{"mla":"Michalska, Julia M., et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology, vol. 42, Springer Nature, 2024, pp. 1051–64, doi:10.1038/s41587-023-01911-8.","ista":"Michalska JM, Lyudchik J, Velicky P, Korinkova H, Watson J, Cenameri A, Sommer CM, Amberg N, Venturino A, Roessler K, Czech T, Höftberger R, Siegert S, Novarino G, Jonas PM, Danzl JG. 2024. Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. 42, 1051–1064.","chicago":"Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology. Springer Nature, 2024. https://doi.org/10.1038/s41587-023-01911-8.","short":"J.M. Michalska, J. Lyudchik, P. Velicky, H. Korinkova, J. Watson, A. Cenameri, C.M. Sommer, N. Amberg, A. Venturino, K. Roessler, T. Czech, R. Höftberger, S. Siegert, G. Novarino, P.M. Jonas, J.G. Danzl, Nature Biotechnology 42 (2024) 1051–1064.","ieee":"J. M. Michalska et al., “Imaging brain tissue architecture across millimeter to nanometer scales,” Nature Biotechnology, vol. 42. Springer Nature, pp. 1051–1064, 2024.","apa":"Michalska, J. M., Lyudchik, J., Velicky, P., Korinkova, H., Watson, J., Cenameri, A., … Danzl, J. G. (2024). Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. Springer Nature. https://doi.org/10.1038/s41587-023-01911-8","ama":"Michalska JM, Lyudchik J, Velicky P, et al. Imaging brain tissue architecture across millimeter to nanometer scales. Nature Biotechnology. 2024;42:1051-1064. doi:10.1038/s41587-023-01911-8"},"publication_status":"published","author":[{"last_name":"Michalska","id":"443DB6DE-F248-11E8-B48F-1D18A9856A87","first_name":"Julia M","orcid":"0000-0003-3862-1235","full_name":"Michalska, Julia M"},{"full_name":"Lyudchik, Julia","last_name":"Lyudchik","id":"46E28B80-F248-11E8-B48F-1D18A9856A87","first_name":"Julia"},{"id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","last_name":"Velicky","first_name":"Philipp","orcid":"0000-0002-2340-7431","full_name":"Velicky, Philipp"},{"full_name":"Korinkova, Hana","first_name":"Hana","last_name":"Korinkova","id":"ee3cb6ca-ec98-11ea-ae11-ff703e2254ed"},{"full_name":"Watson, Jake","orcid":"0000-0002-8698-3823","first_name":"Jake","last_name":"Watson","id":"63836096-4690-11EA-BD4E-32803DDC885E"},{"full_name":"Cenameri, Alban","first_name":"Alban","last_name":"Cenameri","id":"9ac8f577-2357-11eb-997a-e566c5550886"},{"first_name":"Christoph M","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","last_name":"Sommer","full_name":"Sommer, Christoph M","orcid":"0000-0003-1216-9105"},{"last_name":"Amberg","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","first_name":"Nicole","full_name":"Amberg, Nicole","orcid":"0000-0002-3183-8207"},{"full_name":"Venturino, Alessandro","orcid":"0000-0003-2356-9403","id":"41CB84B2-F248-11E8-B48F-1D18A9856A87","last_name":"Venturino","first_name":"Alessandro"},{"full_name":"Roessler, Karl","first_name":"Karl","last_name":"Roessler"},{"full_name":"Czech, Thomas","last_name":"Czech","first_name":"Thomas"},{"full_name":"Höftberger, Romana","first_name":"Romana","last_name":"Höftberger"},{"id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","last_name":"Siegert","first_name":"Sandra","full_name":"Siegert, Sandra","orcid":"0000-0001-8635-0877"},{"orcid":"0000-0002-7673-7178","full_name":"Novarino, Gaia","last_name":"Novarino","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","first_name":"Gaia"},{"last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804"},{"last_name":"Danzl","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","first_name":"Johann G","full_name":"Danzl, Johann G","orcid":"0000-0001-8559-3973"}],"OA_place":"publisher","project":[{"call_identifier":"FWF","_id":"265CB4D0-B435-11E9-9278-68D0E5697425","name":"Optical control of synaptic function via adhesion molecules","grant_number":"I03600"},{"grant_number":"W1232","call_identifier":"FWF","name":"Molecular Drug Targets","_id":"2548AE96-B435-11E9-9278-68D0E5697425"},{"grant_number":"Z00312","name":"Synaptic communication in neuronal microcircuits","_id":"25C5A090-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"name":"High content imaging to decode human immune cell interactions in health and allergic disease","_id":"23889792-32DE-11EA-91FC-C7463DDC885E","grant_number":"LS18-022"},{"_id":"25444568-B435-11E9-9278-68D0E5697425","name":"Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models","call_identifier":"H2020","grant_number":"715508"},{"grant_number":"692692","call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425"},{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385"},{"grant_number":"101026635","_id":"fc2be41b-9c52-11eb-aca3-faa90aa144e9","name":"Synaptic computations of the hippocampal CA3 circuitry","call_identifier":"H2020"}],"corr_author":"1","title":"Imaging brain tissue architecture across millimeter to nanometer scales","_id":"14257","intvolume":" 42","department":[{"_id":"SaSi"},{"_id":"GaNo"},{"_id":"PeJo"},{"_id":"JoDa"},{"_id":"Bio"},{"_id":"RySh"}],"type":"journal_article","oa_version":"Published Version","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"Bio"},{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"E-Lib"}],"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","related_material":{"link":[{"relation":"software","url":"https://github.com/danzllab/CATS"}],"record":[{"relation":"dissertation_contains","id":"18660","status":"deleted"},{"relation":"research_data","id":"13126","status":"public"},{"relation":"dissertation_contains","id":"18674","status":"public"}]},"isi":1,"language":[{"iso":"eng"}],"acknowledgement":"We thank J. Vorlaufer, N. Agudelo-Dueñas, W. Jahr and A. Wartak for microscope maintenance and troubleshooting; C. Kreuzinger, A. Freeman and I. Erber for technical assistance; and M. Tomschik for support with obtaining human samples. We gratefully acknowledge E. Miguel for setting up webKnossos and M. Šuplata for computational support and hardware control. We are grateful to R. Shigemoto and B. Bickel for generous support and M. Sixt and S. Boyd (Stanford University) for discussions and critical reading of the paper. PSD95-HaloTag mice were kindly provided by S. Grant (University of Edinburgh). We acknowledge expert support by Institute of Science and Technology Austria’s scientific computing, imaging and optics, preclinical and lab support facilities and by the Miba machine shop and library. We gratefully acknowledge funding by the following sources: Austrian Science Fund (FWF) grant I3600-B27 (J.G.D.); Austrian Science Fund (FWF) grant DK W1232 (J.G.D. and J.M.M.); Austrian Science Fund (FWF) grant Z 312-B27, Wittgenstein award (P.J.); Austrian Science Fund (FWF) projects I4685-B, I6565-B (SYNABS) and DOC 33-B27 (R.H.); Gesellschaft für Forschungsförderung NÖ (NFB) grant LSC18-022 (J.G.D.); European Union’s Horizon 2020 research and innovation programme, European Research Council (ERC) grant 715508 – REVERSEAUTISM (G.N.); European Union’s Horizon 2020 research and innovation programme, European Research Council (ERC) grant 692692 – GIANTSYN (P.J.); Marie Skłodowska-Curie Actions Fellowship GA no. 665385 under the EU Horizon 2020 program (J.M.M. and J.L.); and Marie Skłodowska-Curie Actions Individual Fellowship no. 101026635 under the EU Horizon 2020 program (J.F.W.).","external_id":{"isi":["001065254200001"],"pmid":["37653226"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"file_size":26065165,"content_type":"application/pdf","file_name":"2024_NatureBiotech_Michalska.pdf","checksum":"57d5fafb16f02dcb9f7dddb1bd7e2a71","date_updated":"2025-01-09T07:48:01Z","relation":"main_file","file_id":"18784","success":1,"date_created":"2025-01-09T07:48:01Z","creator":"dernst","access_level":"open_access"}],"date_updated":"2026-04-14T08:34:35Z","date_published":"2024-07-01T00:00:00Z","doi":"10.1038/s41587-023-01911-8","day":"01","year":"2024","pmid":1,"publication_identifier":{"eissn":["1546-1696"],"issn":["1087-0156"]},"publication":"Nature Biotechnology","ec_funded":1,"article_processing_charge":"Yes (in subscription journal)","volume":42,"date_created":"2023-09-03T22:01:15Z","OA_type":"hybrid","oa":1,"quality_controlled":"1","ddc":["570"],"file_date_updated":"2025-01-09T07:48:01Z","article_type":"original","publisher":"Springer Nature","page":"1051-1064","abstract":[{"text":"Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels at visualizing specific molecules and individual cells but fails to provide tissue context. Here we developed Comprehensive Analysis of Tissues across Scales (CATS), a technology to densely map brain tissue architecture from millimeter regional to nanometer synaptic scales in diverse chemically fixed brain preparations, including rodent and human. CATS uses fixation-compatible extracellular labeling and optical imaging, including stimulated emission depletion or expansion microscopy, to comprehensively delineate cellular structures. It enables three-dimensional reconstruction of single synapses and mapping of synaptic connectivity by identification and analysis of putative synaptic cleft regions. Applying CATS to the mouse hippocampal mossy fiber circuitry, we reconstructed and quantified the synaptic input and output structure of identified neurons. We furthermore demonstrate applicability to clinically derived human tissue samples, including formalin-fixed paraffin-embedded routine diagnostic specimens, for visualizing the cellular architecture of brain tissue in health and disease.","lang":"eng"}],"status":"public","month":"07"},{"ddc":["510"],"publisher":"Springer Nature","file_date_updated":"2024-07-22T09:43:19Z","article_type":"original","volume":72,"article_processing_charge":"Yes (via OA deal)","quality_controlled":"1","oa":1,"date_created":"2023-09-17T22:01:10Z","status":"public","abstract":[{"lang":"eng","text":"For a locally finite set in R2, the order-k Brillouin tessellations form an infinite sequence of convex face-to-face tilings of the plane. If the set is coarsely dense and generic, then the corresponding infinite sequences of minimum and maximum angles are both monotonic in k. As an example, a stationary Poisson point process in R2 is locally finite, coarsely dense, and generic with probability one. For such a set, the distributions of angles in the Voronoi tessellations, Delaunay mosaics, and Brillouin tessellations are independent of the order and can be derived from the formula for angles in order-1 Delaunay mosaics given by Miles (Math. Biosci. 6, 85–127 (1970))."}],"month":"07","page":"29-48","publication":"Discrete and Computational Geometry","ec_funded":1,"publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"isi":1,"acknowledgement":"Work by all authors but A. Garber is supported by the European Research Council (ERC), Grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), Grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), Grant No. I 02979-N35. Work by A. Garber is partially supported by the Alexander von Humboldt Foundation.","language":[{"iso":"eng"}],"scopus_import":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1007/s00454-023-00566-1","pmid":1,"year":"2024","day":"01","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"arxiv":["2204.01076"],"pmid":["39610762"],"isi":["001060727600004"]},"file":[{"date_updated":"2024-07-22T09:43:19Z","relation":"main_file","file_size":892019,"file_name":"2024_DiscreteComputGeom_Edelsbrunner.pdf","checksum":"b207b4e00f904e8ea8a30e24f0251f79","content_type":"application/pdf","creator":"dernst","date_created":"2024-07-22T09:43:19Z","access_level":"open_access","file_id":"17301","success":1}],"date_updated":"2025-04-23T08:41:59Z","date_published":"2024-07-01T00:00:00Z","arxiv":1,"project":[{"grant_number":"788183","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","name":"Alpha Shape Theory Extended","call_identifier":"H2020"},{"grant_number":"Z00342","call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425","name":"Mathematics, Computer Science"},{"grant_number":"I02979-N35","name":"Persistence and stability of geometric complexes","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"corr_author":"1","citation":{"mla":"Edelsbrunner, Herbert, et al. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” Discrete and Computational Geometry, vol. 72, Springer Nature, 2024, pp. 29–48, doi:10.1007/s00454-023-00566-1.","ista":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. 2024. On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. 72, 29–48.","chicago":"Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafari, Teresa Heiss, and Morteza Saghafian. “On Angles in Higher Order Brillouin Tessellations and Related Tilings in the Plane.” Discrete and Computational Geometry. Springer Nature, 2024. https://doi.org/10.1007/s00454-023-00566-1.","short":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, M. Saghafian, Discrete and Computational Geometry 72 (2024) 29–48.","apa":"Edelsbrunner, H., Garber, A., Ghafari, M., Heiss, T., & Saghafian, M. (2024). On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. Springer Nature. https://doi.org/10.1007/s00454-023-00566-1","ieee":"H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, and M. Saghafian, “On angles in higher order Brillouin tessellations and related tilings in the plane,” Discrete and Computational Geometry, vol. 72. Springer Nature, pp. 29–48, 2024.","ama":"Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. On angles in higher order Brillouin tessellations and related tilings in the plane. Discrete and Computational Geometry. 2024;72:29-48. doi:10.1007/s00454-023-00566-1"},"author":[{"orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert"},{"full_name":"Garber, Alexey","first_name":"Alexey","last_name":"Garber"},{"first_name":"Mohadese","last_name":"Ghafari","full_name":"Ghafari, Mohadese"},{"full_name":"Heiss, Teresa","orcid":"0000-0002-1780-2689","id":"4879BB4E-F248-11E8-B48F-1D18A9856A87","last_name":"Heiss","first_name":"Teresa"},{"first_name":"Morteza","last_name":"Saghafian","id":"f86f7148-b140-11ec-9577-95435b8df824","full_name":"Saghafian, Morteza"}],"publication_status":"published","title":"On angles in higher order Brillouin tessellations and related tilings in the plane","type":"journal_article","oa_version":"Published Version","_id":"14345","department":[{"_id":"HeEd"}],"intvolume":" 72"},{"publication_identifier":{"issn":["1751-570X"]},"ec_funded":1,"publication":"Nonlinear Analysis: Hybrid Systems","date_created":"2023-10-08T22:01:15Z","oa":1,"quality_controlled":"1","volume":51,"article_processing_charge":"Yes (in subscription journal)","article_type":"original","file_date_updated":"2024-07-16T10:26:41Z","publisher":"Elsevier","article_number":"101430","ddc":["000"],"month":"02","abstract":[{"text":"We consider the problem of computing the maximal probability of satisfying an \r\n-regular specification for stochastic, continuous-state, nonlinear systems evolving in discrete time. The problem reduces, after automata-theoretic constructions, to finding the maximal probability of satisfying a parity condition on a (possibly hybrid) state space. While characterizing the exact satisfaction probability is open, we show that a lower bound on this probability can be obtained by (I) computing an under-approximation of the qualitative winning region, i.e., states from which the parity condition can be enforced almost surely, and (II) computing the maximal probability of reaching this qualitative winning region.\r\nThe heart of our approach is a technique to symbolically compute the under-approximation of the qualitative winning region in step (I) via a finite-state abstraction of the original system as a \r\n-player parity game. Our abstraction procedure uses only the support of the probabilistic evolution; it does not use precise numerical transition probabilities. We prove that the winning set in the abstract -player game induces an under-approximation of the qualitative winning region in the original synthesis problem, along with a policy to solve it. By combining these contributions with (a) a symbolic fixpoint algorithm to solve \r\n-player games and (b) existing techniques for reachability policy synthesis in stochastic nonlinear systems, we get an abstraction-based algorithm for finding a lower bound on the maximal satisfaction probability.\r\nWe have implemented the abstraction-based algorithm in Mascot-SDS, where we combined the outlined abstraction step with our tool Genie (Majumdar et al., 2023) that solves \r\n-player parity games (through a reduction to Rabin games) more efficiently than existing algorithms. We evaluated our implementation on the nonlinear model of a perturbed bistable switch from the literature. We show empirically that the lower bound on the winning region computed by our approach is precise, by comparing against an over-approximation of the qualitative winning region. Moreover, our implementation outperforms a recently proposed tool for solving this problem by a large margin.","lang":"eng"}],"status":"public","title":"Symbolic control for stochastic systems via finite parity games","publication_status":"published","author":[{"last_name":"Majumdar","first_name":"Rupak","full_name":"Majumdar, Rupak"},{"id":"0834ff3c-6d72-11ec-94e0-b5b0a4fb8598","last_name":"Mallik","first_name":"Kaushik","full_name":"Mallik, Kaushik","orcid":"0000-0001-9864-7475"},{"full_name":"Schmuck, Anne Kathrin","first_name":"Anne Kathrin","last_name":"Schmuck"},{"last_name":"Soudjani","first_name":"Sadegh","full_name":"Soudjani, Sadegh"}],"citation":{"ieee":"R. Majumdar, K. Mallik, A. K. Schmuck, and S. Soudjani, “Symbolic control for stochastic systems via finite parity games,” Nonlinear Analysis: Hybrid Systems, vol. 51, no. 2. Elsevier, 2024.","apa":"Majumdar, R., Mallik, K., Schmuck, A. K., & Soudjani, S. (2024). Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. Elsevier. https://doi.org/10.1016/j.nahs.2023.101430","ama":"Majumdar R, Mallik K, Schmuck AK, Soudjani S. Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. 2024;51(2). doi:10.1016/j.nahs.2023.101430","ista":"Majumdar R, Mallik K, Schmuck AK, Soudjani S. 2024. Symbolic control for stochastic systems via finite parity games. Nonlinear Analysis: Hybrid Systems. 51(2), 101430.","chicago":"Majumdar, Rupak, Kaushik Mallik, Anne Kathrin Schmuck, and Sadegh Soudjani. “Symbolic Control for Stochastic Systems via Finite Parity Games.” Nonlinear Analysis: Hybrid Systems. Elsevier, 2024. https://doi.org/10.1016/j.nahs.2023.101430.","short":"R. Majumdar, K. Mallik, A.K. Schmuck, S. Soudjani, Nonlinear Analysis: Hybrid Systems 51 (2024).","mla":"Majumdar, Rupak, et al. “Symbolic Control for Stochastic Systems via Finite Parity Games.” Nonlinear Analysis: Hybrid Systems, vol. 51, no. 2, 101430, Elsevier, 2024, doi:10.1016/j.nahs.2023.101430."},"corr_author":"1","project":[{"name":"Vigilant Algorithmic Monitoring of Software","_id":"62781420-2b32-11ec-9570-8d9b63373d4d","call_identifier":"H2020","grant_number":"101020093"}],"arxiv":1,"intvolume":" 51","department":[{"_id":"ToHe"}],"_id":"14400","oa_version":"Published Version","type":"journal_article","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"We thank Daniel Hausmann and Nir Piterman for their valuable comments on an earlier version of the manuscript of our other paper [22] where we present, among other things, the parity fixpoint for 2 1/2-player games (for a slightly more general class of games) with a different and indirect proof of correctness. Based on their comments we observed that, unlike the other fixpoints that we present in [22], the parity fixpoint does not follow the exact same structure as its counterpart for 2-player games, which we also use int his paper.\r\nWe also thank Thejaswini Raghavan for observing that our symbolic parity fixpoint algorithm can be solved in quasi-polynomial time using recent improved algorithms for solving \r\n-calculus expressions. This significantly improved the complexity bounds of our algorithm in this paper.\r\nThe work of R. Majumdar and A.-K. Schmuck are partially supported by DFG, Germany project 389792660 TRR 248–CPEC. A.-K. Schmuck is additionally funded through DFG, Germany project (SCHM 3541/1-1). K. Mallik is supported by the ERC project ERC-2020-AdG 101020093. S. Soudjani is supported by the following projects: EPSRC EP/V043676/1, EIC 101070802, and ERC 101089047.","isi":1,"issue":"2","date_published":"2024-02-01T00:00:00Z","date_updated":"2025-04-14T07:55:55Z","external_id":{"isi":["001093188100001"],"arxiv":["2101.00834"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"access_level":"open_access","creator":"dernst","date_created":"2024-07-16T10:26:41Z","success":1,"file_id":"17258","relation":"main_file","date_updated":"2024-07-16T10:26:41Z","file_name":"2024_NonlinearAnalysis_Majumdar.pdf","checksum":"4eab70274d1004ea411f7f0e74c033ac","content_type":"application/pdf","file_size":1787569}],"year":"2024","day":"01","doi":"10.1016/j.nahs.2023.101430"},{"doi":"10.1007/s00440-023-01229-1","year":"2024","day":"01","external_id":{"arxiv":["2210.12060"],"isi":["001118972500001"]},"date_updated":"2025-08-05T13:28:15Z","date_published":"2024-04-01T00:00:00Z","isi":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2210.12060"}],"language":[{"iso":"eng"}],"acknowledgement":"The authors are grateful to Joscha Henheik for his help with the formulas in Appendix B.\r\nLászló Erdős supported by ERC Advanced Grant “RMTBeyond” No. 101020331. Dominik Schröder supported by the SNSF Ambizione Grant PZ00P2 209089.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","type":"journal_article","oa_version":"Preprint","_id":"14408","department":[{"_id":"LaEr"}],"intvolume":" 188","arxiv":1,"citation":{"ama":"Cipolloni G, Erdös L, Schröder DJ. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 2024;188:1131-1182. doi:10.1007/s00440-023-01229-1","ieee":"G. Cipolloni, L. Erdös, and D. J. Schröder, “Mesoscopic central limit theorem for non-Hermitian random matrices,” Probability Theory and Related Fields, vol. 188. Springer Nature, pp. 1131–1182, 2024.","apa":"Cipolloni, G., Erdös, L., & Schröder, D. J. (2024). Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. Springer Nature. https://doi.org/10.1007/s00440-023-01229-1","chicago":"Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Mesoscopic Central Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related Fields. Springer Nature, 2024. https://doi.org/10.1007/s00440-023-01229-1.","short":"G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields 188 (2024) 1131–1182.","ista":"Cipolloni G, Erdös L, Schröder DJ. 2024. Mesoscopic central limit theorem for non-Hermitian random matrices. Probability Theory and Related Fields. 188, 1131–1182.","mla":"Cipolloni, Giorgio, et al. “Mesoscopic Central Limit Theorem for Non-Hermitian Random Matrices.” Probability Theory and Related Fields, vol. 188, Springer Nature, 2024, pp. 1131–82, doi:10.1007/s00440-023-01229-1."},"author":[{"full_name":"Cipolloni, Giorgio","orcid":"0000-0002-4901-7992","id":"42198EFA-F248-11E8-B48F-1D18A9856A87","last_name":"Cipolloni","first_name":"Giorgio"},{"id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","first_name":"László","full_name":"Erdös, László","orcid":"0000-0001-5366-9603"},{"id":"408ED176-F248-11E8-B48F-1D18A9856A87","last_name":"Schröder","first_name":"Dominik J","orcid":"0000-0002-2904-1856","full_name":"Schröder, Dominik J"}],"publication_status":"published","project":[{"grant_number":"101020331","name":"Random matrices beyond Wigner-Dyson-Mehta","_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020"}],"title":"Mesoscopic central limit theorem for non-Hermitian random matrices","abstract":[{"lang":"eng","text":"We prove that the mesoscopic linear statistics ∑if(na(σi−z0)) of the eigenvalues {σi}i of large n×n non-Hermitian random matrices with complex centred i.i.d. entries are asymptotically Gaussian for any H20-functions f around any point z0 in the bulk of the spectrum on any mesoscopic scale 02Te3), coated with polypyrrole (PPy). Taking advantage of the PPy coating, the Bi2Te3@PPy composite presents strong ionic absorption affinity, high oxidation resistance, and high structural stability. The ZIBs based on Bi2Te3@PPy cathodes exhibit high capacities and ultra‐long lifespans of over 5000 cycles. They also present outstanding stability even under bending. In addition, we analyze here the reaction mechanism using in situ X‐ray diffraction, X‐ray photoelectron spectroscopy, and computational tools and demonstrate that, in the aqueous system, Zn2+ is not inserted into the cathode as previously assumed. In contrast, proton charge storage dominates the process. Overall, this work not only shows the great potential of LMCs as ZIBs cathode materials and the advantages of PPy coating, but also clarifies the charge/discharge mechanism in rechargeable ZIBs based on LMCs.","lang":"eng"}],"status":"public","month":"01","publication_identifier":{"eissn":["1521-4095"],"issn":["0935-9648"]},"publication":"Advanced Materials","acknowledged_ssus":[{"_id":"EM-Fac"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Mechanical Engineering","Mechanics of Materials","General Materials Science"],"scopus_import":"1","isi":1,"issue":"1","language":[{"iso":"eng"}],"acknowledgement":"G.Z. and Q.S. contributed equally to this work. This work was supported by the National Natural Science Foundation of China (52105329, 52175300) and the Heilongjiang Provincial Natural Science Foundation of China (LH2022E059). G.Z., X.L., and C.Z. thank the China Scholarship Council (CSC) for the scholarship support. This research was supported by the Scientific Service Units of ISTA through resources provided by the Electron Microscopy Facility. S.H. and M.I. acknowledge funding by ISTA and Werner Siemens.","external_id":{"isi":["001085681000001"],"pmid":["37555532"]},"date_published":"2024-01-04T00:00:00Z","date_updated":"2025-04-15T06:36:40Z","doi":"10.1002/adma.202305128","day":"04","year":"2024","pmid":1,"publication_status":"published","author":[{"last_name":"Zeng","first_name":"Guifang","full_name":"Zeng, Guifang"},{"first_name":"Qing","last_name":"Sun","full_name":"Sun, Qing"},{"first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","last_name":"Horta","full_name":"Horta, Sharona"},{"full_name":"Wang, Shang","first_name":"Shang","last_name":"Wang"},{"full_name":"Lu, Xuan","first_name":"Xuan","last_name":"Lu"},{"last_name":"Zhang","first_name":"Chaoyue","full_name":"Zhang, Chaoyue"},{"full_name":"Li, Jing","first_name":"Jing","last_name":"Li"},{"full_name":"Li, Junshan","first_name":"Junshan","last_name":"Li"},{"full_name":"Ci, Lijie","first_name":"Lijie","last_name":"Ci"},{"full_name":"Tian, Yanhong","last_name":"Tian","first_name":"Yanhong"},{"orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","first_name":"Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"}],"citation":{"mla":"Zeng, Guifang, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials, vol. 36, no. 1, 2305128, Wiley, 2024, doi:10.1002/adma.202305128.","ista":"Zeng G, Sun Q, Horta S, Wang S, Lu X, Zhang C, Li J, Li J, Ci L, Tian Y, Ibáñez M, Cabot A. 2024. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 36(1), 2305128.","short":"G. Zeng, Q. Sun, S. Horta, S. Wang, X. Lu, C. Zhang, J. Li, J. Li, L. Ci, Y. Tian, M. Ibáñez, A. Cabot, Advanced Materials 36 (2024).","chicago":"Zeng, Guifang, Qing Sun, Sharona Horta, Shang Wang, Xuan Lu, Chaoyue Zhang, Jing Li, et al. “A Layered Bi2Te3@PPy Cathode for Aqueous Zinc Ion Batteries: Mechanism and Application in Printed Flexible Batteries.” Advanced Materials. Wiley, 2024. https://doi.org/10.1002/adma.202305128.","apa":"Zeng, G., Sun, Q., Horta, S., Wang, S., Lu, X., Zhang, C., … Cabot, A. (2024). A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. Wiley. https://doi.org/10.1002/adma.202305128","ieee":"G. Zeng et al., “A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries,” Advanced Materials, vol. 36, no. 1. Wiley, 2024.","ama":"Zeng G, Sun Q, Horta S, et al. A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries. Advanced Materials. 2024;36(1). doi:10.1002/adma.202305128"},"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"title":"A layered Bi2Te3@PPy cathode for aqueous zinc ion batteries: Mechanism and application in printed flexible batteries","_id":"14435","department":[{"_id":"MaIb"}],"intvolume":" 36","type":"journal_article","oa_version":"None"},{"isi":1,"acknowledgement":"The authors would like to thank Karolína Kubiasová and Iñigo Saiz-Fernández for valuable scientific discussions. Open access publishing supported by the National Technical Library in Prague. This work was supported by the Palacký University Olomouc Young Researcher Grant Competition (JG_2020_002), by the Internal Grant Agency of Palacký University Olomouc (IGA_PrF_2023_016, IGA_PrF_2023_031), by the Ministry of Education, Youth and Sports of the Czech Republic through the European Regional Development Fund-Project Plants as a tool for sustainable global development (CZ.02.1.01/0.0/0.0/16_019/0000827) and the project Support of mobility at Palacký University Olomouc II. (CZ.02.2.69/0.0/0.0/18_053/0016919). The Biacore T200 SPR instrument was provided by the WISB Research Technology Facility within the School of Life Sciences, University of Warwick.","language":[{"iso":"eng"}],"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","doi":"10.1007/s10725-023-01083-0","day":"01","year":"2024","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"isi":["001084334300001"]},"file":[{"creator":"dernst","date_created":"2024-07-16T08:13:24Z","access_level":"open_access","file_id":"17252","success":1,"date_updated":"2024-07-16T08:13:24Z","relation":"main_file","file_size":2847929,"file_name":"2024_PlantGrowthReg_Bieleszova.pdf","checksum":"e63271b1d57c1f03c1d993fd62cba59c","content_type":"application/pdf"}],"date_published":"2024-04-01T00:00:00Z","date_updated":"2024-07-16T08:13:39Z","publication_status":"published","citation":{"ista":"Bieleszová K, Hladík P, Kubala M, Napier R, Brunoni F, Gelová Z, Fiedler L, Kulich I, Strnad M, Doležal K, Novák O, Friml J, Žukauskaitė A. 2024. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 102, 589–602.","short":"K. Bieleszová, P. Hladík, M. Kubala, R. Napier, F. Brunoni, Z. Gelová, L. Fiedler, I. Kulich, M. Strnad, K. Doležal, O. Novák, J. Friml, A. Žukauskaitė, Plant Growth Regulation 102 (2024) 589–602.","chicago":"Bieleszová, Kristýna, Pavel Hladík, Martin Kubala, Richard Napier, Federica Brunoni, Zuzana Gelová, Lukas Fiedler, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation. Springer Nature, 2024. https://doi.org/10.1007/s10725-023-01083-0.","mla":"Bieleszová, Kristýna, et al. “New Fluorescent Auxin Derivatives: Anti-Auxin Activity and Accumulation Patterns in Arabidopsis Thaliana.” Plant Growth Regulation, vol. 102, Springer Nature, 2024, pp. 589–602, doi:10.1007/s10725-023-01083-0.","apa":"Bieleszová, K., Hladík, P., Kubala, M., Napier, R., Brunoni, F., Gelová, Z., … Žukauskaitė, A. (2024). New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. Springer Nature. https://doi.org/10.1007/s10725-023-01083-0","ieee":"K. Bieleszová et al., “New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana,” Plant Growth Regulation, vol. 102. Springer Nature, pp. 589–602, 2024.","ama":"Bieleszová K, Hladík P, Kubala M, et al. New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation. 2024;102:589-602. doi:10.1007/s10725-023-01083-0"},"author":[{"full_name":"Bieleszová, Kristýna","first_name":"Kristýna","last_name":"Bieleszová"},{"full_name":"Hladík, Pavel","first_name":"Pavel","last_name":"Hladík"},{"full_name":"Kubala, Martin","first_name":"Martin","last_name":"Kubala"},{"last_name":"Napier","first_name":"Richard","full_name":"Napier, Richard"},{"full_name":"Brunoni, Federica","last_name":"Brunoni","first_name":"Federica"},{"first_name":"Zuzana","last_name":"Gelová","id":"0AE74790-0E0B-11E9-ABC7-1ACFE5697425","orcid":"0000-0003-4783-1752","full_name":"Gelová, Zuzana"},{"last_name":"Fiedler","id":"7c417475-8972-11ed-ae7b-8b674ca26986","first_name":"Lukas","full_name":"Fiedler, Lukas"},{"first_name":"Ivan","id":"57a1567c-8314-11eb-9063-c9ddc3451a54","last_name":"Kulich","full_name":"Kulich, Ivan"},{"full_name":"Strnad, Miroslav","last_name":"Strnad","first_name":"Miroslav"},{"full_name":"Doležal, Karel","last_name":"Doležal","first_name":"Karel"},{"last_name":"Novák","first_name":"Ondřej","full_name":"Novák, Ondřej"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jiří","full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596"},{"first_name":"Asta","last_name":"Žukauskaitė","full_name":"Žukauskaitė, Asta"}],"title":"New fluorescent auxin derivatives: Anti-auxin activity and accumulation patterns in Arabidopsis thaliana","type":"journal_article","oa_version":"Published Version","_id":"14447","department":[{"_id":"JiFr"}],"intvolume":" 102","ddc":["580"],"publisher":"Springer Nature","article_type":"original","file_date_updated":"2024-07-16T08:13:24Z","volume":102,"article_processing_charge":"Yes (via OA deal)","quality_controlled":"1","date_created":"2023-10-22T22:01:15Z","oa":1,"status":"public","abstract":[{"lang":"eng","text":"Auxin belongs among major phytohormones and governs multiple aspects of plant growth and development. The establishment of auxin concentration gradients, determines, among other processes, plant organ positioning and growth responses to environmental stimuli.\r\nHerein we report the synthesis of new NBD- or DNS-labelled IAA derivatives and the elucidation of their biological activity, fluorescence properties and subcellular accumulation patterns in planta. These novel compounds did not show auxin-like activity, but instead antagonized physiological auxin effects. The DNS-labelled derivatives FL5 and FL6 showed strong anti-auxin activity in roots and hypocotyls, which also occurred at the level of gene transcription as confirmed by quantitative PCR analysis. The auxin antagonism of our derivatives was further demonstrated in vitro using an SPR-based binding assay. The NBD-labelled compound FL4 with the best fluorescence properties proved to be unsuitable to study auxin accumulation patterns in planta. On the other hand, the strongest anti-auxin activity possessing compounds FL5 and FL6 could be useful to study binding mechanisms to auxin receptors and for manipulations of auxin-regulated processes."}],"month":"04","page":"589-602","publication":"Plant Growth Regulation","publication_identifier":{"eissn":["1573-5087"],"issn":["0167-6903"]}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"Open access funding provided by Università degli Studi di Trieste within the CRUI-CARE Agreement. Funding was provided by Austrian Science Fund (Grant No. F65), Horizon 2020 (Grant No. 754411) and Österreichische Forschungsförderungsgesellschaft.","issue":"2","date_published":"2024-01-01T00:00:00Z","date_updated":"2025-04-23T07:39:14Z","external_id":{"pmid":["38187995"],"arxiv":["2203.04579"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"file_id":"17251","success":1,"creator":"dernst","date_created":"2024-07-16T08:08:54Z","access_level":"open_access","file_size":4412285,"file_name":"2024_NeuralCompApplications_Cornalba.pdf","checksum":"04573d8e74c6119b97c2ca0a984e19a1","content_type":"application/pdf","date_updated":"2024-07-16T08:08:54Z","relation":"main_file"}],"day":"01","year":"2024","pmid":1,"doi":"10.1007/s00521-023-09033-7","title":"Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading","publication_status":"published","citation":{"mla":"Cornalba, Federico, et al. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications, vol. 36, no. 2, Springer Nature, 2024, pp. 617–37, doi:10.1007/s00521-023-09033-7.","ista":"Cornalba F, Disselkamp C, Scassola D, Helf C. 2024. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 36(2), 617–637.","short":"F. Cornalba, C. Disselkamp, D. Scassola, C. Helf, Neural Computing and Applications 36 (2024) 617–637.","chicago":"Cornalba, Federico, Constantin Disselkamp, Davide Scassola, and Christopher Helf. “Multi-Objective Reward Generalization: Improving Performance of Deep Reinforcement Learning for Applications in Single-Asset Trading.” Neural Computing and Applications. Springer Nature, 2024. https://doi.org/10.1007/s00521-023-09033-7.","apa":"Cornalba, F., Disselkamp, C., Scassola, D., & Helf, C. (2024). Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. Springer Nature. https://doi.org/10.1007/s00521-023-09033-7","ieee":"F. Cornalba, C. Disselkamp, D. Scassola, and C. Helf, “Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading,” Neural Computing and Applications, vol. 36, no. 2. Springer Nature, pp. 617–637, 2024.","ama":"Cornalba F, Disselkamp C, Scassola D, Helf C. Multi-objective reward generalization: Improving performance of Deep Reinforcement Learning for applications in single-asset trading. Neural Computing and Applications. 2024;36(2):617-637. doi:10.1007/s00521-023-09033-7"},"author":[{"id":"2CEB641C-A400-11E9-A717-D712E6697425","last_name":"Cornalba","first_name":"Federico","full_name":"Cornalba, Federico","orcid":"0000-0002-6269-5149"},{"full_name":"Disselkamp, Constantin","last_name":"Disselkamp","first_name":"Constantin"},{"last_name":"Scassola","first_name":"Davide","full_name":"Scassola, Davide"},{"first_name":"Christopher","last_name":"Helf","full_name":"Helf, Christopher"}],"project":[{"grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"},{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"corr_author":"1","arxiv":1,"department":[{"_id":"JuFi"}],"intvolume":" 36","_id":"14451","oa_version":"Published Version","type":"journal_article","date_created":"2023-10-22T22:01:16Z","oa":1,"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","volume":36,"article_type":"original","file_date_updated":"2024-07-16T08:08:54Z","publisher":"Springer Nature","ddc":["000"],"page":"617-637","month":"01","abstract":[{"lang":"eng","text":"We investigate the potential of Multi-Objective, Deep Reinforcement Learning for stock and cryptocurrency single-asset trading: in particular, we consider a Multi-Objective algorithm which generalizes the reward functions and discount factor (i.e., these components are not specified a priori, but incorporated in the learning process). Firstly, using several important assets (BTCUSD, ETHUSDT, XRPUSDT, AAPL, SPY, NIFTY50), we verify the reward generalization property of the proposed Multi-Objective algorithm, and provide preliminary statistical evidence showing increased predictive stability over the corresponding Single-Objective strategy. Secondly, we show that the Multi-Objective algorithm has a clear edge over the corresponding Single-Objective strategy when the reward mechanism is sparse (i.e., when non-null feedback is infrequent over time). Finally, we discuss the generalization properties with respect to the discount factor. The entirety of our code is provided in open-source format."}],"status":"public","publication_identifier":{"issn":["0941-0643"],"eissn":["1433-3058"]},"ec_funded":1,"publication":"Neural Computing and Applications"},{"publication":"Molecular Ecology","publication_identifier":{"issn":["0962-1083"],"eissn":["1365-294X"]},"file_date_updated":"2025-01-09T07:52:12Z","article_type":"original","publisher":"Wiley","ddc":["570"],"article_number":"e17160","date_created":"2023-10-29T23:01:17Z","OA_type":"hybrid","oa":1,"quality_controlled":"1","volume":33,"article_processing_charge":"Yes (in subscription journal)","month":"12","abstract":[{"lang":"eng","text":"Inversions are thought to play a key role in adaptation and speciation, suppressing recombination between diverging populations. Genes influencing adaptive traits cluster in inversions, and changes in inversion frequencies are associated with environmental differences. However, in many organisms, it is unclear if inversions are geographically and taxonomically widespread. The intertidal snail, Littorina saxatilis, is one such example. Strong associations between putative polymorphic inversions and phenotypic differences have been demonstrated between two ecotypes of L. saxatilis in Sweden and inferred elsewhere, but no direct evidence for inversion polymorphism currently exists across the species range. Using whole genome data from 107 snails, most inversion polymorphisms were found to be widespread across the species range. The frequencies of some inversion arrangements were significantly different among ecotypes, suggesting a parallel adaptive role. Many inversions were also polymorphic in the sister species, L. arcana, hinting at an ancient origin."}],"status":"public","title":"Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana)","citation":{"chicago":"Reeve, James, Roger K. Butlin, Eva L. Koch, Sean Stankowski, and Rui Faria. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology. Wiley, 2024. https://doi.org/10.1111/mec.17160.","short":"J. Reeve, R.K. Butlin, E.L. Koch, S. Stankowski, R. Faria, Molecular Ecology 33 (2024).","ista":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. 2024. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 33(24), e17160.","mla":"Reeve, James, et al. “Chromosomal Inversion Polymorphisms Are Widespread across the Species Ranges of Rough Periwinkles (Littorina Saxatilis and L. Arcana).” Molecular Ecology, vol. 33, no. 24, e17160, Wiley, 2024, doi:10.1111/mec.17160.","ama":"Reeve J, Butlin RK, Koch EL, Stankowski S, Faria R. Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. 2024;33(24). doi:10.1111/mec.17160","apa":"Reeve, J., Butlin, R. K., Koch, E. L., Stankowski, S., & Faria, R. (2024). Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana). Molecular Ecology. Wiley. https://doi.org/10.1111/mec.17160","ieee":"J. Reeve, R. K. Butlin, E. L. Koch, S. Stankowski, and R. Faria, “Chromosomal inversion polymorphisms are widespread across the species ranges of rough periwinkles (Littorina saxatilis and L. arcana),” Molecular Ecology, vol. 33, no. 24. Wiley, 2024."},"author":[{"full_name":"Reeve, James","first_name":"James","last_name":"Reeve"},{"first_name":"Roger K.","last_name":"Butlin","full_name":"Butlin, Roger K."},{"full_name":"Koch, Eva L.","first_name":"Eva L.","last_name":"Koch"},{"full_name":"Stankowski, Sean","first_name":"Sean","last_name":"Stankowski","id":"43161670-5719-11EA-8025-FABC3DDC885E"},{"full_name":"Faria, Rui","last_name":"Faria","first_name":"Rui"}],"publication_status":"published","OA_place":"publisher","oa_version":"Published Version","type":"journal_article","department":[{"_id":"NiBa"}],"intvolume":" 33","_id":"14463","language":[{"iso":"eng"}],"acknowledgement":"We would like to thank members of the Littorina team for their advice and feedback during this project. In particular, we thank Alan Le Moan, who inspired us to look at heterozygosity differences to identify inversions, and Katherine Hearn for helping with the PCA scripts. We thank Edinburgh Genomics for library preparation and sequencing. Sample collections, sequencing and data preparation were supported by the European Research Council (ERC-2015-AdG-693030- BARRIERS) and the Natural Environment Research Council (NE/P001610/1). The analysis was supported by the Swedish Research Council (vetenskaprådet; 2018-03695_VR) and the Portuguese Foundation for Science and Technology (Fundación para a Ciência e Tecnologia) through a research project (PTDC/BIA-EVL/1614/2021) and CEEC contract (2020.00275.CEECIND).","isi":1,"issue":"24","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","scopus_import":"1","day":"01","year":"2024","pmid":1,"doi":"10.1111/mec.17160","date_published":"2024-12-01T00:00:00Z","date_updated":"2025-01-09T07:53:18Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"isi":["001085119000001"],"pmid":["37843465"]},"file":[{"date_updated":"2025-01-09T07:52:12Z","relation":"main_file","file_size":6228700,"file_name":"2024_MolecularEcology_Reeve.pdf","checksum":"686576036663f489c2d079df3079d126","content_type":"application/pdf","creator":"dernst","date_created":"2025-01-09T07:52:12Z","access_level":"open_access","file_id":"18785","success":1}]},{"title":"Frequent horizontal chromosome transfer between asexual fungal insect pathogens","OA_place":"publisher","corr_author":"1","project":[{"name":"Epidemics in ant societies on a chip","_id":"2649B4DE-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"771402"}],"author":[{"full_name":"Habig, Michael","last_name":"Habig","first_name":"Michael"},{"id":"406F989C-F248-11E8-B48F-1D18A9856A87","last_name":"Grasse","first_name":"Anna V","full_name":"Grasse, Anna V"},{"last_name":"Müller","first_name":"Judith","full_name":"Müller, Judith"},{"last_name":"Stukenbrock","first_name":"Eva H.","full_name":"Stukenbrock, Eva H."},{"first_name":"Hanna","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7","last_name":"Leitner","full_name":"Leitner, Hanna"},{"orcid":"0000-0002-2193-3868","full_name":"Cremer, Sylvia","first_name":"Sylvia","last_name":"Cremer","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87"}],"citation":{"ieee":"M. Habig, A. V. Grasse, J. Müller, E. H. Stukenbrock, H. Leitner, and S. Cremer, “Frequent horizontal chromosome transfer between asexual fungal insect pathogens,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11. National Academy of Sciences, 2024.","apa":"Habig, M., Grasse, A. V., Müller, J., Stukenbrock, E. H., Leitner, H., & Cremer, S. (2024). Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2316284121","ama":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(11). doi:10.1073/pnas.2316284121","mla":"Habig, Michael, et al. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 11, e2316284121, National Academy of Sciences, 2024, doi:10.1073/pnas.2316284121.","ista":"Habig M, Grasse AV, Müller J, Stukenbrock EH, Leitner H, Cremer S. 2024. Frequent horizontal chromosome transfer between asexual fungal insect pathogens. Proceedings of the National Academy of Sciences of the United States of America. 121(11), e2316284121.","short":"M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","chicago":"Habig, Michael, Anna V Grasse, Judith Müller, Eva H. Stukenbrock, Hanna Leitner, and Sylvia Cremer. “Frequent Horizontal Chromosome Transfer between Asexual Fungal Insect Pathogens.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2316284121."},"publication_status":"published","oa_version":"Published Version","type":"journal_article","intvolume":" 121","department":[{"_id":"SyCr"}],"_id":"14478","acknowledgement":"We thank Bernhardt Steinwender, Jorgen Eilenberg, and Nicolai V. Meyling for the fungal strains. We further thank Chengshu Wang for providing the short sequencing reads for M. guizhouense ARESF977 he used for his published genome assembly, and Kristian Ullrich for help in the bioinformatics analysis for methylation pattern in Nanopore reads, and the VBC and the Max Planck Society for the use of their sequencing centers. We thank Barbara Milutinović and Hinrich Schulenburg for discussion, and Tal Dagan and Jens Rolff for comments on a previous version of the manuscript. Fig. 1A was created with BioRender.com. This study received funding by the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (No. 771402; EPIDEMICSonCHIP) to S.C. and by the German Research Foundation (DFG grant HA9263/1-1) to M.H.","language":[{"iso":"eng"}],"APC_amount":"3040,36 EUR","issue":"11","isi":1,"scopus_import":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"day":"12","year":"2024","doi":"10.1073/pnas.2316284121","date_updated":"2025-08-05T13:30:51Z","date_published":"2024-03-12T00:00:00Z","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)"},"file":[{"access_level":"open_access","creator":"dernst","date_created":"2024-03-19T09:02:57Z","success":1,"file_id":"15124","relation":"main_file","date_updated":"2024-03-19T09:02:57Z","checksum":"f5e871db617b682edc71fcd08670dc81","file_name":"2024_PNAS_Habig.pdf","content_type":"application/pdf","file_size":5750361}],"external_id":{"isi":["001207630200005"],"pmid":["38442176"]},"ec_funded":1,"publication":"Proceedings of the National Academy of Sciences of the United States of America","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"publisher":"National Academy of Sciences","file_date_updated":"2024-03-19T09:02:57Z","article_type":"original","article_number":"e2316284121","ddc":["570"],"quality_controlled":"1","date_created":"2023-10-31T13:30:00Z","oa":1,"OA_type":"hybrid","volume":121,"article_processing_charge":"Yes (in subscription journal)","month":"03","status":"public","abstract":[{"lang":"eng","text":"Entire chromosomes are typically only transmitted vertically from one generation to the next. The horizontal transfer of such chromosomes has long been considered improbable, yet gained recent support in several pathogenic fungi where it may affect the fitness or host specificity. To date, it is unknown how these transfers occur, how common they are and whether they can occur between different species. In this study, we show multiple independent instances of horizontal transfers of the same accessory chromosome between two distinct strains of the asexual entomopathogenic fungusMetarhizium robertsiiduring experimental co-infection of its insect host, the Argentine ant. Notably, only the one chromosome – but no other – was transferred from the donor to the recipient strain. The recipient strain, now harboring the accessory chromosome, exhibited a competitive advantage under certain host conditions. By phylogenetic analysis we further demonstrate that the same accessory chromosome was horizontally transferred in a natural environment betweenM. robertsiiand another congeneric insect pathogen,M. guizhouense. Hence horizontal chromosome transfer is not limited to the observed frequent events within species during experimental infections but also occurs naturally across species. The transferred accessory chromosome contains genes that might be involved in its preferential horizontal transfer, encoding putative histones and histone-modifying enzymes, but also putative virulence factors that may support its establishment. Our study reveals that both intra- and interspecies horizontal transfer of entire chromosomes is more frequent than previously assumed, likely representing a not uncommon mechanism for gene exchange.Significance StatementThe enormous success of bacterial pathogens has been attributed to their ability to exchange genetic material between one another. Similarly, in eukaryotes, horizontal transfer of genetic material allowed the spread of virulence factors across species. The horizontal transfer of whole chromosomes could be an important pathway for such exchange of genetic material, but little is known about the origin of transferable chromosomes and how frequently they are exchanged. Here, we show that the transfer of accessory chromosomes - chromosomes that are non-essential but may provide fitness benefits - is common during fungal co-infections and is even possible between distant pathogenic species, highlighting the importance of horizontal gene transfer via chromosome transfer also for the evolution and function of eukaryotic pathogens."}]},{"author":[{"full_name":"Csata, Eniko","last_name":"Csata","first_name":"Eniko"},{"last_name":"Perez-Escudero","first_name":"Alfonso","full_name":"Perez-Escudero, Alfonso"},{"full_name":"Laury, Emmanuel","first_name":"Emmanuel","last_name":"Laury"},{"full_name":"Leitner, Hanna","last_name":"Leitner","id":"8fc5c6f6-5903-11ec-abad-c83f046253e7","first_name":"Hanna"},{"full_name":"Latil, Gerard","last_name":"Latil","first_name":"Gerard"},{"first_name":"Juerge","last_name":"Heinze","full_name":"Heinze, Juerge"},{"full_name":"Simpson, Stephen","first_name":"Stephen","last_name":"Simpson"},{"id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","last_name":"Cremer","first_name":"Sylvia","full_name":"Cremer, Sylvia","orcid":"0000-0002-2193-3868"},{"full_name":"Dussutour, Audrey","last_name":"Dussutour","first_name":"Audrey"}],"publication_status":"published","citation":{"mla":"Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6, doi:10.1016/j.cub.2024.01.017.","chicago":"Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal Infection Alters Collective Nutritional Intake of Ant Colonies.” Current Biology. Elsevier, 2024. https://doi.org/10.1016/j.cub.2024.01.017.","short":"E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S. Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.","ista":"Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 34(4), 902–909.e6.","ama":"Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective nutritional intake of ant colonies. Current Biology. 2024;34(4):902-909.e6. doi:10.1016/j.cub.2024.01.017","apa":"Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J., … Dussutour, A. (2024). Fungal infection alters collective nutritional intake of ant colonies. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2024.01.017","ieee":"E. Csata et al., “Fungal infection alters collective nutritional intake of ant colonies,” Current Biology, vol. 34, no. 4. Elsevier, p. 902–909.e6, 2024."},"title":"Fungal infection alters collective nutritional intake of ant colonies","_id":"14479","intvolume":" 34","department":[{"_id":"SyCr"}],"type":"journal_article","oa_version":"Preprint","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"4","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2023.10.26.564092"}],"isi":1,"acknowledgement":"We are sincerely grateful to the referees for their valuable comments and suggestions, which helped us to improve the paper. We are thankful to Jorgen Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou, and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard, Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore, we thank Anna V. Grasse for help with the immune gene expression analyses. We thank Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by the CNRS.","language":[{"iso":"eng"}],"external_id":{"pmid":["38307022"],"isi":["001195884300001"]},"date_updated":"2025-08-05T13:29:38Z","date_published":"2024-02-26T00:00:00Z","doi":"10.1016/j.cub.2024.01.017","pmid":1,"year":"2024","day":"26","publication_identifier":{"issn":["0960-9822"],"eissn":["1879-0445"]},"publication":"Current Biology","article_processing_charge":"No","volume":34,"quality_controlled":"1","date_created":"2023-10-31T13:30:20Z","oa":1,"publisher":"Elsevier","article_type":"original","page":"902-909.e6","status":"public","abstract":[{"lang":"eng","text":"In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6 Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12 but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16 How nutrition influences host-parasite interactions is not well understood, as studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23 We used the nutritional geometry framework24 to investigate the role of amino acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant, Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First, using 18 diets varying in AA:C composition, we established that the fungus performed best on the high-amino-acid diet 1:4. Second, we found that the fungus reached this optimal diet when given various diet pairings, revealing its ability to cope with nutritional challenges. Third, we showed that the optimal fungal diet reduced the lifespan of healthy ants when compared with a high-carbohydrate diet but had no effect on infected ants. Fourth, we revealed that infected ant colonies, given a choice between the optimal fungal diet and a high-carbohydrate diet, chose the optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling fungal infection from host immune response, we demonstrated that infected ants foraged on the optimal fungal diet in response to immune activation and not as a result of parasite manipulation. Therefore, we revealed that infected ant colonies chose a diet that is costly for survival in the long term but beneficial in the short term—a form of collective self-medication."}],"month":"02"},{"publication":"International Journal of Computer Vision","publication_identifier":{"eissn":["1573-1405"],"issn":["0920-5691"]},"publisher":"Springer Nature","file_date_updated":"2024-07-22T11:07:14Z","article_type":"original","ddc":["000"],"quality_controlled":"1","oa":1,"date_created":"2023-11-05T23:00:54Z","volume":132,"article_processing_charge":"Yes (via OA deal)","month":"04","status":"public","abstract":[{"lang":"eng","text":"Portrait viewpoint and illumination editing is an important problem with several applications in VR/AR, movies, and photography. Comprehensive knowledge of geometry and illumination is critical for obtaining photorealistic results. Current methods are unable to explicitly model in 3D while handling both viewpoint and illumination editing from a single image. In this paper, we propose VoRF, a novel approach that can take even a single portrait image as input and relight human heads under novel illuminations that can be viewed from arbitrary viewpoints. VoRF represents a human head as a continuous volumetric field and learns a prior model of human heads using a coordinate-based MLP with individual latent spaces for identity and illumination. The prior model is learned in an auto-decoder manner over a diverse class of head shapes and appearances, allowing VoRF to generalize to novel test identities from a single input image. Additionally, VoRF has a reflectance MLP that uses the intermediate features of the prior model for rendering One-Light-at-A-Time (OLAT) images under novel views. We synthesize novel illuminations by combining these OLAT images with target environment maps. Qualitative and quantitative evaluations demonstrate the effectiveness of VoRF for relighting and novel view synthesis, even when applied to unseen subjects under uncontrolled illumination. This work is an extension of Rao et al. (VoRF: Volumetric Relightable Faces 2022). We provide extensive evaluation and ablative studies of our model and also provide an application, where any face can be relighted using textual input."}],"page":"1148-1166","title":"A deeper analysis of volumetric relightiable faces","citation":{"ista":"Rao P, Mallikarjun BR, Fox G, Weyrich T, Bickel B, Pfister H, Matusik W, Zhan F, Tewari A, Theobalt C, Elgharib M. 2024. A deeper analysis of volumetric relightiable faces. International Journal of Computer Vision. 132, 1148–1166.","chicago":"Rao, Pramod, B. R. Mallikarjun, Gereon Fox, Tim Weyrich, Bernd Bickel, Hanspeter Pfister, Wojciech Matusik, et al. “A Deeper Analysis of Volumetric Relightiable Faces.” International Journal of Computer Vision. Springer Nature, 2024. https://doi.org/10.1007/s11263-023-01899-3.","short":"P. Rao, B.R. Mallikarjun, G. Fox, T. Weyrich, B. Bickel, H. Pfister, W. Matusik, F. Zhan, A. Tewari, C. Theobalt, M. Elgharib, International Journal of Computer Vision 132 (2024) 1148–1166.","mla":"Rao, Pramod, et al. “A Deeper Analysis of Volumetric Relightiable Faces.” International Journal of Computer Vision, vol. 132, Springer Nature, 2024, pp. 1148–66, doi:10.1007/s11263-023-01899-3.","ieee":"P. Rao et al., “A deeper analysis of volumetric relightiable faces,” International Journal of Computer Vision, vol. 132. Springer Nature, pp. 1148–1166, 2024.","apa":"Rao, P., Mallikarjun, B. R., Fox, G., Weyrich, T., Bickel, B., Pfister, H., … Elgharib, M. (2024). A deeper analysis of volumetric relightiable faces. International Journal of Computer Vision. Springer Nature. https://doi.org/10.1007/s11263-023-01899-3","ama":"Rao P, Mallikarjun BR, Fox G, et al. A deeper analysis of volumetric relightiable faces. International Journal of Computer Vision. 2024;132:1148-1166. doi:10.1007/s11263-023-01899-3"},"publication_status":"published","author":[{"last_name":"Rao","first_name":"Pramod","full_name":"Rao, Pramod"},{"last_name":"Mallikarjun","first_name":"B. R.","full_name":"Mallikarjun, B. R."},{"last_name":"Fox","first_name":"Gereon","full_name":"Fox, Gereon"},{"full_name":"Weyrich, Tim","last_name":"Weyrich","first_name":"Tim"},{"first_name":"Bernd","id":"49876194-F248-11E8-B48F-1D18A9856A87","last_name":"Bickel","orcid":"0000-0001-6511-9385","full_name":"Bickel, Bernd"},{"first_name":"Hanspeter","last_name":"Pfister","full_name":"Pfister, Hanspeter"},{"first_name":"Wojciech","last_name":"Matusik","full_name":"Matusik, Wojciech"},{"last_name":"Zhan","first_name":"Fangneng","full_name":"Zhan, Fangneng"},{"last_name":"Tewari","first_name":"Ayush","full_name":"Tewari, Ayush"},{"first_name":"Christian","last_name":"Theobalt","full_name":"Theobalt, Christian"},{"full_name":"Elgharib, Mohamed","first_name":"Mohamed","last_name":"Elgharib"}],"oa_version":"Published Version","type":"journal_article","department":[{"_id":"BeBi"}],"intvolume":" 132","_id":"14488","acknowledgement":"Open Access funding enabled and organized by Projekt DEAL.","language":[{"iso":"eng"}],"isi":1,"scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","pmid":1,"year":"2024","day":"01","doi":"10.1007/s11263-023-01899-3","date_updated":"2025-08-05T13:28:58Z","date_published":"2024-04-01T00:00:00Z","external_id":{"isi":["001091935600002"],"pmid":["38549787"]},"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"date_updated":"2024-07-22T11:07:14Z","relation":"main_file","file_size":9942520,"checksum":"5eef1d920f6fe700d7856098000d05f1","file_name":"2024_IJCV_Rao.pdf","content_type":"application/pdf","creator":"dernst","date_created":"2024-07-22T11:07:14Z","access_level":"open_access","file_id":"17304","success":1}]},{"publication_identifier":{"eissn":["1793-6659"],"issn":["0129-055X"]},"ec_funded":1,"publication":"Reviews in Mathematical Physics","month":"10","abstract":[{"lang":"eng","text":"It is a remarkable property of BCS theory that the ratio of the energy gap at zero temperature Ξ\r\n and the critical temperature Tc is (approximately) given by a universal constant, independent of the microscopic details of the fermionic interaction. This universality has rigorously been proven quite recently in three spatial dimensions and three different limiting regimes: weak coupling, low density and high density. The goal of this short note is to extend the universal behavior to lower dimensions d=1,2 and give an exemplary proof in the weak coupling limit."}],"status":"public","date_created":"2023-11-15T23:48:14Z","oa":1,"OA_type":"hybrid","quality_controlled":"1","article_processing_charge":"Yes (in subscription journal)","volume":36,"article_type":"original","file_date_updated":"2025-01-09T07:56:28Z","publisher":"World Scientific Publishing","article_number":"2360005 ","ddc":["510"],"intvolume":" 36","department":[{"_id":"GradSch"},{"_id":"LaEr"},{"_id":"RoSe"}],"_id":"14542","oa_version":"Published Version","type":"journal_article","title":"Universality in low-dimensional BCS theory","author":[{"first_name":"Sven Joscha","last_name":"Henheik","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb","orcid":"0000-0003-1106-327X","full_name":"Henheik, Sven Joscha"},{"orcid":"0000-0003-4476-2288","full_name":"Lauritsen, Asbjørn Bækgaard","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","last_name":"Lauritsen","first_name":"Asbjørn Bækgaard"},{"full_name":"Roos, Barbara","orcid":"0000-0002-9071-5880","first_name":"Barbara","last_name":"Roos","id":"5DA90512-D80F-11E9-8994-2E2EE6697425"}],"publication_status":"published","citation":{"ama":"Henheik SJ, Lauritsen AB, Roos B. Universality in low-dimensional BCS theory. Reviews in Mathematical Physics. 2024;36(9). doi:10.1142/s0129055x2360005x","apa":"Henheik, S. J., Lauritsen, A. B., & Roos, B. (2024). Universality in low-dimensional BCS theory. Reviews in Mathematical Physics. World Scientific Publishing. https://doi.org/10.1142/s0129055x2360005x","ieee":"S. J. Henheik, A. B. Lauritsen, and B. Roos, “Universality in low-dimensional BCS theory,” Reviews in Mathematical Physics, vol. 36, no. 9. World Scientific Publishing, 2024.","short":"S.J. Henheik, A.B. Lauritsen, B. Roos, Reviews in Mathematical Physics 36 (2024).","chicago":"Henheik, Sven Joscha, Asbjørn Bækgaard Lauritsen, and Barbara Roos. “Universality in Low-Dimensional BCS Theory.” Reviews in Mathematical Physics. World Scientific Publishing, 2024. https://doi.org/10.1142/s0129055x2360005x.","ista":"Henheik SJ, Lauritsen AB, Roos B. 2024. Universality in low-dimensional BCS theory. Reviews in Mathematical Physics. 36(9), 2360005.","mla":"Henheik, Sven Joscha, et al. “Universality in Low-Dimensional BCS Theory.” Reviews in Mathematical Physics, vol. 36, no. 9, 2360005, World Scientific Publishing, 2024, doi:10.1142/s0129055x2360005x."},"corr_author":"1","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","name":"Random matrices beyond Wigner-Dyson-Mehta","call_identifier":"H2020","grant_number":"101020331"},{"grant_number":"I06427","_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b","name":"Mathematical Challenges in BCS Theory of Superconductivity"}],"OA_place":"publisher","arxiv":1,"date_published":"2024-10-01T00:00:00Z","date_updated":"2026-04-07T13:01:40Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file":[{"file_size":503910,"content_type":"application/pdf","file_name":"2024_ReviewsmathPhysics_Henheik.pdf","checksum":"2b053a4223b4db14b90520999ec56054","date_updated":"2025-01-09T07:56:28Z","relation":"main_file","file_id":"18786","success":1,"date_created":"2025-01-09T07:56:28Z","creator":"dernst","access_level":"open_access"}],"external_id":{"isi":["001099640300002"],"arxiv":["2301.05621"]},"year":"2024","day":"01","doi":"10.1142/s0129055x2360005x","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","related_material":{"record":[{"status":"public","id":"19540","relation":"dissertation_contains"},{"status":"public","id":"18135","relation":"dissertation_contains"}]},"scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"We thank Robert Seiringer for comments on the paper. J. H. gratefully acknowledges partial financial support by the ERC Advanced Grant “RMTBeyond”No. 101020331.This research was funded in part by the Austrian Science Fund (FWF) grantnumber I6427.","isi":1,"issue":"9"},{"publication_status":"published","author":[{"full_name":"Kaiyrzhanov, Rauan","last_name":"Kaiyrzhanov","first_name":"Rauan"},{"last_name":"Rad","first_name":"Aboulfazl","full_name":"Rad, Aboulfazl"},{"full_name":"Lin, Sheng-Jia","last_name":"Lin","first_name":"Sheng-Jia"},{"full_name":"Bertoli-Avella, Aida","last_name":"Bertoli-Avella","first_name":"Aida"},{"full_name":"Kallemeijn, Wouter W","last_name":"Kallemeijn","first_name":"Wouter W"},{"full_name":"Godwin, Annie","first_name":"Annie","last_name":"Godwin"},{"full_name":"Zaki, Maha S","last_name":"Zaki","first_name":"Maha S"},{"id":"3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3","last_name":"Huang","first_name":"Kevin","orcid":"0000-0002-2512-7812","full_name":"Huang, 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Dayana","first_name":"Dayana","last_name":"Vazquez"},{"full_name":"Vetro, Annalisa","first_name":"Annalisa","last_name":"Vetro"},{"last_name":"Waterham","first_name":"Hans R","full_name":"Waterham, Hans R"},{"full_name":"Zaman, Mashaya","first_name":"Mashaya","last_name":"Zaman"},{"last_name":"Schrader","first_name":"Tina A","full_name":"Schrader, Tina A"},{"full_name":"Chung, Wendy K","last_name":"Chung","first_name":"Wendy K"},{"first_name":"Renzo","last_name":"Guerrini","full_name":"Guerrini, Renzo"},{"full_name":"Lupski, James R","first_name":"James R","last_name":"Lupski"},{"full_name":"Gleeson, Joseph","last_name":"Gleeson","first_name":"Joseph"},{"last_name":"Suri","first_name":"Mohnish","full_name":"Suri, Mohnish"},{"full_name":"Jamshidi, Yalda","last_name":"Jamshidi","first_name":"Yalda"},{"last_name":"Bhatia","first_name":"Kailash P","full_name":"Bhatia, Kailash P"},{"full_name":"Vona, Barbara","last_name":"Vona","first_name":"Barbara"},{"full_name":"Schrader, Michael","first_name":"Michael","last_name":"Schrader"},{"first_name":"Mariasavina","last_name":"Severino","full_name":"Severino, Mariasavina"},{"last_name":"Guille","first_name":"Matthew","full_name":"Guille, Matthew"},{"first_name":"Edward W","last_name":"Tate","full_name":"Tate, Edward W"},{"last_name":"Varshney","first_name":"Gaurav K","full_name":"Varshney, Gaurav K"},{"first_name":"Henry","last_name":"Houlden","full_name":"Houlden, Henry"},{"full_name":"Maroofian, Reza","last_name":"Maroofian","first_name":"Reza"}],"citation":{"ieee":"R. Kaiyrzhanov et al., “Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders,” Brain, vol. 147, no. 4. Oxford University Press, pp. 1436–1456, 2024.","apa":"Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W., Godwin, A., … Maroofian, R. (2024). Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. Oxford University Press. https://doi.org/10.1093/brain/awad380","ama":"Kaiyrzhanov R, Rad A, Lin S-J, et al. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. 2024;147(4):1436-1456. doi:10.1093/brain/awad380","mla":"Kaiyrzhanov, Rauan, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” Brain, vol. 147, no. 4, Oxford University Press, 2024, pp. 1436–56, doi:10.1093/brain/awad380.","ista":"Kaiyrzhanov R, Rad A, Lin S-J, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Ghayoor Karimiani E, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Akay Tayfun G, Al Saman A, Alswaid A, Amiri N, Asilova N, Shotelersuk V, Yeetong P, Azam M, Babaei M, Bahrami Monajemi G, Mohammadi P, Samie S, Banu SH, Basto JP, Kortüm F, Bauer M, Bauer P, Beetz C, Garshasbi M, Hameed Issa A, Eyaid W, Ahmed H, Hashemi N, Hassanpour K, Herman I, Ibrohimov S, Abdul-Majeed BA, Imdad M, Isrofilov M, Kaiyal Q, Khan S, Kirmse B, Koster J, Lourenço CM, Mitani T, Moldovan O, Murphy D, Najafi M, Pehlivan D, Rocha ME, Salpietro V, Schmidts M, Shalata A, Mahroum M, Talbeya JK, Taylor RW, Vazquez D, Vetro A, Waterham HR, Zaman M, Schrader TA, Chung WK, Guerrini R, Lupski JR, Gleeson J, Suri M, Jamshidi Y, Bhatia KP, Vona B, Schrader M, Severino M, Guille M, Tate EW, Varshney GK, Houlden H, Maroofian R. 2024. Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain. 147(4), 1436–1456.","short":"R. Kaiyrzhanov, A. Rad, S.-J. Lin, A. Bertoli-Avella, W.W. Kallemeijn, A. Godwin, M.S. Zaki, K. Huang, T. Lau, C. Petree, S. Efthymiou, E. Ghayoor Karimiani, M. Hempel, E.A. Normand, S. Rudnik-Schöneborn, U.A. Schatz, M.P. Baggelaar, M. Ilyas, T. Sultan, J.R. Alvi, M. Ganieva, B. Fowler, R. Aanicai, G. Akay Tayfun, A. Al Saman, A. Alswaid, N. Amiri, N. Asilova, V. Shotelersuk, P. Yeetong, M. Azam, M. Babaei, G. Bahrami Monajemi, P. Mohammadi, S. Samie, S.H. Banu, J.P. Basto, F. Kortüm, M. Bauer, P. Bauer, C. Beetz, M. Garshasbi, A. Hameed Issa, W. Eyaid, H. Ahmed, N. Hashemi, K. Hassanpour, I. Herman, S. Ibrohimov, B.A. Abdul-Majeed, M. Imdad, M. Isrofilov, Q. Kaiyal, S. Khan, B. Kirmse, J. Koster, C.M. Lourenço, T. Mitani, O. Moldovan, D. Murphy, M. Najafi, D. Pehlivan, M.E. Rocha, V. Salpietro, M. Schmidts, A. Shalata, M. Mahroum, J.K. Talbeya, R.W. Taylor, D. Vazquez, A. Vetro, H.R. Waterham, M. Zaman, T.A. Schrader, W.K. Chung, R. Guerrini, J.R. Lupski, J. Gleeson, M. Suri, Y. Jamshidi, K.P. Bhatia, B. Vona, M. Schrader, M. Severino, M. Guille, E.W. Tate, G.K. Varshney, H. Houlden, R. Maroofian, Brain 147 (2024) 1436–1456.","chicago":"Kaiyrzhanov, Rauan, Aboulfazl Rad, Sheng-Jia Lin, Aida Bertoli-Avella, Wouter W Kallemeijn, Annie Godwin, Maha S Zaki, et al. “Bi-Allelic ACBD6 Variants Lead to a Neurodevelopmental Syndrome with Progressive and Complex Movement Disorders.” Brain. Oxford University Press, 2024. https://doi.org/10.1093/brain/awad380."},"extern":"1","title":"Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders","type":"journal_article","oa_version":"Submitted Version","_id":"14543","intvolume":" 147","department":[{"_id":"GradSch"}],"issue":"4","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","scopus_import":"1","keyword":["Neurology (clinical)"],"doi":"10.1093/brain/awad380","day":"01","year":"2024","pmid":1,"file":[{"access_level":"open_access","creator":"dernst","date_created":"2024-07-16T08:22:13Z","success":1,"file_id":"17254","relation":"main_file","date_updated":"2024-07-16T08:22:13Z","checksum":"0ee7a8ab9300225d60968f7a3e3cfa0d","file_name":"2024_Brain_Kaiyrzhanov.pdf","content_type":"application/pdf","file_size":2641456}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"pmid":["37951597"]},"date_published":"2024-04-01T00:00:00Z","date_updated":"2024-07-16T08:23:24Z","publication":"Brain","publication_identifier":{"eissn":["1460-2156"],"issn":["0006-8950"]},"ddc":["570"],"article_type":"original","file_date_updated":"2024-07-16T08:22:13Z","publisher":"Oxford University Press","volume":147,"article_processing_charge":"No","oa":1,"date_created":"2023-11-16T12:36:51Z","quality_controlled":"1","abstract":[{"text":"The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed, plays a role in the acylation of lipids and proteins, and regulates the N-myristoylation of proteins via N-myristoyltransferase enzymes (NMTs). However, its precise function in cells is still unclear, as is the consequence of ACBD6 defects on human pathophysiology. Utilizing exome sequencing and extensive international data sharing efforts, we identified 45 affected individuals from 28 unrelated families (consanguinity 93%) with bi-allelic pathogenic, predominantly loss-of-function (18/20) variants in ACBD6. We generated zebrafish and Xenopus tropicalis acbd6 knockouts by CRISPR/Cas9 and characterized the role of ACBD6 on protein N-myristoylation with YnMyr chemical proteomics in the model organisms and human cells, with the latter also being subjected further to ACBD6 peroxisomal localization studies. The affected individuals (23 males and 22 females), with ages ranging from 1 to 50 years old, typically present with a complex and progressive disease involving moderate-to-severe global developmental delay/intellectual disability (100%) with significant expressive language impairment (98%), movement disorders (97%), facial dysmorphism (95%), and mild cerebellar ataxia (85%) associated with gait impairment (94%), limb spasticity/hypertonia (76%), oculomotor (71%) and behavioural abnormalities (65%), overweight (59%), microcephaly (39%) and epilepsy (33%). The most conspicuous and common movement disorder was dystonia (94%), frequently leading to early-onset progressive postural deformities (97%), limb dystonia (55%), and cervical dystonia (31%). A jerky tremor in the upper limbs (63%), a mild head tremor (59%), parkinsonism/hypokinesia developing with advancing age (32%), and simple motor and vocal tics were among other frequent movement disorders. Midline brain malformations including corpus callosum abnormalities (70%), hypoplasia/agenesis of the anterior commissure (66%), short midbrain and small inferior cerebellar vermis (38% each), as well as hypertrophy of the clava (24%) were common neuroimaging findings. acbd6-deficient zebrafish and Xenopus models effectively recapitulated many clinical phenotypes reported in patients including movement disorders, progressive neuromotor impairment, seizures, microcephaly, craniofacial dysmorphism, and midbrain defects accompanied by developmental delay with increased mortality over time. Unlike ACBD5, ACBD6 did not show a peroxisomal localisation and ACBD6-deficiency was not associated with altered peroxisomal parameters in patient fibroblasts. Significant differences in YnMyr-labelling were observed for 68 co- and 18 post-translationally N-myristoylated proteins in patient-derived fibroblasts. N-Myristoylation was similarly affected in acbd6-deficient zebrafish and Xenopus tropicalis models, including Fus, Marcks, and Chchd-related proteins implicated in neurological diseases. The present study provides evidence that bi-allelic pathogenic variants in ACBD6 lead to a distinct neurodevelopmental syndrome accompanied by complex and progressive cognitive and movement disorders.","lang":"eng"}],"status":"public","month":"04","page":"1436-1456"},{"_id":"14652","department":[{"_id":"MaIb"}],"intvolume":" 674","type":"journal_article","oa_version":"None","author":[{"first_name":"Shyam Lal","last_name":"Gupta","full_name":"Gupta, Shyam Lal"},{"full_name":"Singh, Saurabh","orcid":"0000-0003-2209-5269","first_name":"Saurabh","last_name":"Singh","id":"12d625da-9cb3-11ed-9667-af09d37d3f0a"},{"full_name":"Kumar, Sumit","last_name":"Kumar","first_name":"Sumit"},{"first_name":"Unknown","last_name":"Anupam","full_name":"Anupam, Unknown"},{"full_name":"Thakur, Samjeet Singh","first_name":"Samjeet Singh","last_name":"Thakur"},{"full_name":"Kumar, Ashish","last_name":"Kumar","first_name":"Ashish"},{"last_name":"Panwar","first_name":"Sanjay","full_name":"Panwar, Sanjay"},{"full_name":"Diwaker, D.","first_name":"D.","last_name":"Diwaker"}],"publication_status":"published","citation":{"ama":"Gupta SL, Singh S, Kumar S, et al. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 2024;674(2). doi:10.1016/j.physb.2023.415539","ieee":"S. L. Gupta et al., “Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys,” Physica B: Condensed Matter, vol. 674, no. 2. Elsevier, 2024.","apa":"Gupta, S. L., Singh, S., Kumar, S., Anupam, U., Thakur, S. S., Kumar, A., … Diwaker, D. (2024). Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. Elsevier. https://doi.org/10.1016/j.physb.2023.415539","mla":"Gupta, Shyam Lal, et al. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter, vol. 674, no. 2, 415539, Elsevier, 2024, doi:10.1016/j.physb.2023.415539.","short":"S.L. Gupta, S. Singh, S. Kumar, U. Anupam, S.S. Thakur, A. Kumar, S. Panwar, D. Diwaker, Physica B: Condensed Matter 674 (2024).","chicago":"Gupta, Shyam Lal, Saurabh Singh, Sumit Kumar, Unknown Anupam, Samjeet Singh Thakur, Ashish Kumar, Sanjay Panwar, and D. Diwaker. “Ab-Initio Stability of Iridium Based Newly Proposed Full and Quaternary Heusler Alloys.” Physica B: Condensed Matter. Elsevier, 2024. https://doi.org/10.1016/j.physb.2023.415539.","ista":"Gupta SL, Singh S, Kumar S, Anupam U, Thakur SS, Kumar A, Panwar S, Diwaker D. 2024. Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys. Physica B: Condensed Matter. 674(2), 415539."},"title":"Ab-initio stability of Iridium based newly proposed full and quaternary heusler alloys","external_id":{"isi":["001127429000001"]},"date_updated":"2025-09-04T11:29:46Z","date_published":"2024-02-01T00:00:00Z","doi":"10.1016/j.physb.2023.415539","day":"01","year":"2024","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","scopus_import":"1","isi":1,"issue":"2","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0921-4526"]},"publication":"Physica B: Condensed Matter","abstract":[{"lang":"eng","text":"In order to demonstrate the stability of newly proposed iridium-based Ir2Cr(In,Sn) and IrRhCr(In,Sn) heusler alloys, we present ab-initio analysis of these alloys by examining various properties to prove their stability. The stability of these alloys can be inferred from different cohesive and formation energies as well as positive phonon frequencies. Their electronic structure results indicate that they are semi-metals in nature. The magnetic moments are computed using the Slater-Pauling formula and exhibit a high value, with the Cr atom contributing the most in all alloys. Mulliken’s charge analysis results show that our alloys contain a range of linkages, mainly ionic and covalent ones. The ductility and mechanical stability of these alloys are confirmed by elastic constants viz. Poisson’s ratio, Pugh’s ratio, and many different types of elastic moduli."}],"status":"public","month":"02","volume":674,"article_processing_charge":"No","date_created":"2023-12-10T23:00:56Z","quality_controlled":"1","article_number":"415539","article_type":"original","publisher":"Elsevier"},{"publication":"International Journal of Mass Spectrometry","publication_identifier":{"issn":["1387-3806"]},"publisher":"Elsevier","article_type":"original","file_date_updated":"2024-07-16T08:27:34Z","article_number":"117168","ddc":["540"],"quality_controlled":"1","oa":1,"date_created":"2023-12-10T23:00:57Z","article_processing_charge":"Yes (in subscription journal)","volume":495,"month":"01","status":"public","abstract":[{"text":"Mass spectrometry imaging (MSI) is a powerful analytical technique for the two-dimensional (2D) localization of chemicals on surfaces. Conventional MSI experiments require to predefine the surface of interest based on photographic or microscopic images. Typically, these boundaries can no longer be changed or adjusted once the experiment has been started. In terms of a more interactive approach we recently developed a pen-like ionization interface which is directly connected to the mass spectrometer. The device allows the user to ionize chemicals by desorption electrospray ionization (DESI) and to freely move the interface over a surface of interest. A mini camera, which is mounted on the tip of the pen, magnifies the desorption area and enables a simple positioning of the pen. The combination of optical data from the camera module and chemical data obtained by mass analysis facilitates a novel type of imaging experiment: interactive mass spectrometry imaging (IMSI). For this application, we present a novel approach for a robust, optical flow-based motion detection. While the live video stream from the camera is used to track the pen's motion across the surface a post-acquisition algorithm correlates the coordinates of the pen trajectory with respective mass spectra obtained from a simultaneous mass spectrometric data acquisition. This algorithm is no longer dependent on a single, manually applied optical marker on the sample surface, which has to be visible on all video frames throughout the analysis. The advanced DESI-IMSI method was successfully tested on inkjet-printed letters as well as mouse brain tissue samples. Validation of the results was done by comparing DESI-IMSI with standard DESI-MSI data.","lang":"eng"}],"title":"Advanced motion tracking for interactive mass spectrometry imaging (IMSI)","citation":{"ama":"Kluibenschedl F, Ploner A, Meisenbichler C, Konrat R, Müller T. Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. 2024;495. doi:10.1016/j.ijms.2023.117168","ieee":"F. Kluibenschedl, A. Ploner, C. Meisenbichler, R. Konrat, and T. Müller, “Advanced motion tracking for interactive mass spectrometry imaging (IMSI),” International Journal of Mass Spectrometry, vol. 495. Elsevier, 2024.","apa":"Kluibenschedl, F., Ploner, A., Meisenbichler, C., Konrat, R., & Müller, T. (2024). Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. Elsevier. https://doi.org/10.1016/j.ijms.2023.117168","short":"F. Kluibenschedl, A. Ploner, C. Meisenbichler, R. Konrat, T. Müller, International Journal of Mass Spectrometry 495 (2024).","chicago":"Kluibenschedl, Florian, Anna Ploner, Christina Meisenbichler, Robert Konrat, and Thomas Müller. “Advanced Motion Tracking for Interactive Mass Spectrometry Imaging (IMSI).” International Journal of Mass Spectrometry. Elsevier, 2024. https://doi.org/10.1016/j.ijms.2023.117168.","ista":"Kluibenschedl F, Ploner A, Meisenbichler C, Konrat R, Müller T. 2024. Advanced motion tracking for interactive mass spectrometry imaging (IMSI). International Journal of Mass Spectrometry. 495, 117168.","mla":"Kluibenschedl, Florian, et al. “Advanced Motion Tracking for Interactive Mass Spectrometry Imaging (IMSI).” International Journal of Mass Spectrometry, vol. 495, 117168, Elsevier, 2024, doi:10.1016/j.ijms.2023.117168."},"author":[{"last_name":"Kluibenschedl","id":"7499e70e-eb2c-11ec-b98b-f925648bc9d9","first_name":"Florian","full_name":"Kluibenschedl, Florian"},{"first_name":"Anna","last_name":"Ploner","full_name":"Ploner, Anna"},{"last_name":"Meisenbichler","first_name":"Christina","full_name":"Meisenbichler, Christina"},{"first_name":"Robert","last_name":"Konrat","full_name":"Konrat, Robert"},{"first_name":"Thomas","last_name":"Müller","full_name":"Müller, Thomas"}],"publication_status":"published","oa_version":"Published Version","type":"journal_article","intvolume":" 495","department":[{"_id":"GradSch"}],"_id":"14653","acknowledgement":"We would like to thank Marco Sealey Cardona, PhD for help with the mouse brain samples and acknowledge the financial support by 1669 Förderkreis of the University of Innsbruck, Austria Wirtschaftsservice (AWS), D. Swarovski KG and Tyrolean Science Fund (TWF).","language":[{"iso":"eng"}],"isi":1,"scopus_import":"1","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","day":"01","year":"2024","doi":"10.1016/j.ijms.2023.117168","date_published":"2024-01-01T00:00:00Z","date_updated":"2025-09-04T11:30:59Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"isi":["001125054400001"]},"file":[{"creator":"dernst","date_created":"2024-07-16T08:27:34Z","access_level":"open_access","file_id":"17256","success":1,"date_updated":"2024-07-16T08:27:34Z","relation":"main_file","file_size":3003139,"checksum":"6c5eb6dc07af70a59251d2c6fed38894","file_name":"2024_IJMS_Kluibenschedl.pdf","content_type":"application/pdf"}]},{"volume":56,"article_processing_charge":"Yes (via OA deal)","quality_controlled":"1","date_created":"2023-12-10T23:00:58Z","oa":1,"ddc":["510"],"publisher":"London Mathematical Society","article_type":"original","file_date_updated":"2024-07-16T10:35:10Z","page":"796-802","status":"public","abstract":[{"lang":"eng","text":"The classical Steinitz theorem states that if the origin belongs to the interior of the convex hull of a set 𝑆⊂ℝ𝑑, then there are at most 2𝑑 points of 𝑆 whose convex hull contains the origin in the interior. Bárány, Katchalski,and Pach proved the following quantitative version of Steinitz’s theorem. Let 𝑄 be a convex polytope in ℝ𝑑 containing the standard Euclidean unit ball 𝐁𝑑. Then there exist at most 2𝑑 vertices of 𝑄 whose convex hull 𝑄′ satisfies 𝑟𝐁𝑑⊂𝑄′ with 𝑟⩾𝑑−2𝑑. They conjectured that 𝑟⩾𝑐𝑑−1∕2 holds with a universal constant 𝑐>0. We prove 𝑟⩾15𝑑2, the first polynomial lower bound on 𝑟. Furthermore, we show that 𝑟 is not greater than 2/√𝑑."}],"month":"02","publication_identifier":{"eissn":["1469-2120"],"issn":["0024-6093"]},"publication":"Bulletin of the London Mathematical Society","scopus_import":"1","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","issue":"2","isi":1,"acknowledgement":"M.N. was supported by the János Bolyai Scholarship of the Hungarian Academy of Sciences aswell as the National Research, Development and Innovation Fund (NRDI) grants K119670 andK131529, and the ÚNKP-22-5 New National Excellence Program of the Ministry for Innovationand Technology from the source of the NRDI as well as the ELTE TKP 2021-NKTA-62 fundingscheme","language":[{"iso":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"isi":["001113277100001"],"arxiv":["2212.04308"]},"file":[{"relation":"main_file","date_updated":"2024-07-16T10:35:10Z","checksum":"30ea0694757bc668cf7cd15ae357b35e","file_name":"2024_BulletinLondonMathSoc_Ivanov.pdf","content_type":"application/pdf","file_size":111756,"access_level":"open_access","creator":"dernst","date_created":"2024-07-16T10:35:10Z","success":1,"file_id":"17259"}],"date_published":"2024-02-01T00:00:00Z","date_updated":"2025-09-04T11:31:49Z","doi":"10.1112/blms.12965","day":"01","year":"2024","corr_author":"1","author":[{"last_name":"Ivanov","id":"87744F66-5C6F-11EA-AFE0-D16B3DDC885E","first_name":"Grigory","full_name":"Ivanov, Grigory"},{"full_name":"Naszódi, Márton","first_name":"Márton","last_name":"Naszódi"}],"publication_status":"published","citation":{"ama":"Ivanov G, Naszódi M. Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. 2024;56(2):796-802. doi:10.1112/blms.12965","apa":"Ivanov, G., & Naszódi, M. (2024). Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. London Mathematical Society. https://doi.org/10.1112/blms.12965","ieee":"G. Ivanov and M. Naszódi, “Quantitative Steinitz theorem: A polynomial bound,” Bulletin of the London Mathematical Society, vol. 56, no. 2. London Mathematical Society, pp. 796–802, 2024.","mla":"Ivanov, Grigory, and Márton Naszódi. “Quantitative Steinitz Theorem: A Polynomial Bound.” Bulletin of the London Mathematical Society, vol. 56, no. 2, London Mathematical Society, 2024, pp. 796–802, doi:10.1112/blms.12965.","chicago":"Ivanov, Grigory, and Márton Naszódi. “Quantitative Steinitz Theorem: A Polynomial Bound.” Bulletin of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/blms.12965.","short":"G. Ivanov, M. Naszódi, Bulletin of the London Mathematical Society 56 (2024) 796–802.","ista":"Ivanov G, Naszódi M. 2024. Quantitative Steinitz theorem: A polynomial bound. Bulletin of the London Mathematical Society. 56(2), 796–802."},"title":"Quantitative Steinitz theorem: A polynomial bound","arxiv":1,"_id":"14660","department":[{"_id":"UlWa"}],"intvolume":" 56","type":"journal_article","oa_version":"Published Version"},{"date_updated":"2025-09-04T11:32:49Z","date_published":"2024-02-01T00:00:00Z","external_id":{"arxiv":["2211.04408"],"isi":["001166812100008"]},"year":"2024","day":"01","doi":"10.1109/TIT.2023.3334032","scopus_import":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","acknowledgement":"The work of Yihan Zhang was supported by the European Union’s Horizon 2020 Research and Innovation Programme under Grant 682203-ERC-[Inf-Speed-Tradeoff]. The work of Shashank Vatedka was supported in part by the Core Research Grant from the Science and\r\nEngineering Research Board, India, under Grant CRG/2022/004464; and in\r\npart by the Department of Science and Technology (DST), India, under Grant\r\nDST/INT/RUS/RSF/P-41/2020 (TPN No. 65025).","language":[{"iso":"eng"}],"issue":"2","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2211.04408","open_access":"1"}],"isi":1,"intvolume":" 70","department":[{"_id":"MaMo"}],"_id":"14665","oa_version":"Preprint","type":"journal_article","title":"Multiple packing: Lower bounds via error exponents","corr_author":"1","author":[{"id":"2ce5da42-b2ea-11eb-bba5-9f264e9d002c","last_name":"Zhang","first_name":"Yihan","orcid":"0000-0002-6465-6258","full_name":"Zhang, Yihan"},{"first_name":"Shashank","last_name":"Vatedka","full_name":"Vatedka, Shashank"}],"citation":{"short":"Y. Zhang, S. Vatedka, IEEE Transactions on Information Theory 70 (2024) 1008–1039.","chicago":"Zhang, Yihan, and Shashank Vatedka. “Multiple Packing: Lower Bounds via Error Exponents.” IEEE Transactions on Information Theory. IEEE, 2024. https://doi.org/10.1109/TIT.2023.3334032.","ista":"Zhang Y, Vatedka S. 2024. Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. 70(2), 1008–1039.","mla":"Zhang, Yihan, and Shashank Vatedka. “Multiple Packing: Lower Bounds via Error Exponents.” IEEE Transactions on Information Theory, vol. 70, no. 2, IEEE, 2024, pp. 1008–39, doi:10.1109/TIT.2023.3334032.","ama":"Zhang Y, Vatedka S. Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. 2024;70(2):1008-1039. doi:10.1109/TIT.2023.3334032","apa":"Zhang, Y., & Vatedka, S. (2024). Multiple packing: Lower bounds via error exponents. IEEE Transactions on Information Theory. IEEE. https://doi.org/10.1109/TIT.2023.3334032","ieee":"Y. Zhang and S. Vatedka, “Multiple packing: Lower bounds via error exponents,” IEEE Transactions on Information Theory, vol. 70, no. 2. IEEE, pp. 1008–1039, 2024."},"publication_status":"published","arxiv":1,"page":"1008-1039","month":"02","status":"public","abstract":[{"text":"We derive lower bounds on the maximal rates for multiple packings in high-dimensional Euclidean spaces. For any N > 0 and L ∈ Z ≥2 , a multiple packing is a set C of points in R n such that any point in R n lies in the intersection of at most L - 1 balls of radius √ nN around points in C . This is a natural generalization of the sphere packing problem. We study the multiple packing problem for both bounded point sets whose points have norm at most √ nP for some constant P > 0, and unbounded point sets whose points are allowed to be anywhere in R n . Given a well-known connection with coding theory, multiple packings can be viewed as the Euclidean analog of list-decodable codes, which are well-studied over finite fields. We derive the best known lower bounds on the optimal multiple packing density. This is accomplished by establishing an inequality which relates the list-decoding error exponent for additive white Gaussian noise channels, a quantity of average-case nature, to the list-decoding radius, a quantity of worst-case nature. We also derive novel bounds on the list-decoding error exponent for infinite constellations and closed-form expressions for the list-decoding error exponents for the power-constrained AWGN channel, which may be of independent interest beyond multiple packing.","lang":"eng"}],"quality_controlled":"1","oa":1,"date_created":"2023-12-10T23:01:00Z","volume":70,"article_processing_charge":"No","publisher":"IEEE","article_type":"original","publication_identifier":{"eissn":["1557-9654"],"issn":["0018-9448"]},"publication":"IEEE Transactions on Information Theory"},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"external_id":{"pmid":["38070137"]},"file":[{"success":1,"file_id":"17260","access_level":"open_access","creator":"dernst","date_created":"2024-07-16T11:50:03Z","checksum":"3f0ee62e04bf5a44b45b035662826e95","file_name":"2024_STARProtoc_Amberg.pdf","content_type":"application/pdf","file_size":8871807,"relation":"main_file","date_updated":"2024-07-16T11:50:03Z"}],"date_published":"2024-03-15T00:00:00Z","date_updated":"2025-04-15T08:23:06Z","doi":"10.1016/j.xpro.2023.102771","day":"15","year":"2024","pmid":1,"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Neuroscience"],"scopus_import":"1","issue":"1","language":[{"iso":"eng"}],"acknowledgement":"This research was supported by the Scientific Service Units (SSU) at IST Austria through resources provided by the Imaging & Optics Facility (IOF) and Preclinical Facilities (PCF). N.A. received support from FWF Firnberg-Programme (T 1031). G.C. received support from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 754411 as an ISTplus postdoctoral fellow. This work was also supported by IST Austria institutional funds, FWF SFB F78 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 725780 LinPro) to S.H.","_id":"14683","intvolume":" 5","department":[{"_id":"SiHi"}],"type":"journal_article","oa_version":"Published Version","citation":{"ista":"Amberg N, Cheung GT, Hippenmeyer S. 2024. Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. 5(1), 102771.","chicago":"Amberg, Nicole, Giselle T Cheung, and Simon Hippenmeyer. “Protocol for Sorting Cells from Mouse Brains Labeled with Mosaic Analysis with Double Markers by Flow Cytometry.” STAR Protocols. Elsevier, 2024. https://doi.org/10.1016/j.xpro.2023.102771.","short":"N. Amberg, G.T. Cheung, S. Hippenmeyer, STAR Protocols 5 (2024).","mla":"Amberg, Nicole, et al. “Protocol for Sorting Cells from Mouse Brains Labeled with Mosaic Analysis with Double Markers by Flow Cytometry.” STAR Protocols, vol. 5, no. 1, 102771, Elsevier, 2024, doi:10.1016/j.xpro.2023.102771.","ieee":"N. Amberg, G. T. Cheung, and S. Hippenmeyer, “Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry,” STAR Protocols, vol. 5, no. 1. Elsevier, 2024.","apa":"Amberg, N., Cheung, G. T., & Hippenmeyer, S. (2024). Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. Elsevier. https://doi.org/10.1016/j.xpro.2023.102771","ama":"Amberg N, Cheung GT, Hippenmeyer S. Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry. STAR Protocols. 2024;5(1). doi:10.1016/j.xpro.2023.102771"},"publication_status":"published","author":[{"first_name":"Nicole","last_name":"Amberg","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","full_name":"Amberg, Nicole","orcid":"0000-0002-3183-8207"},{"full_name":"Cheung, Giselle T","orcid":"0000-0001-8457-2572","first_name":"Giselle T","id":"471195F6-F248-11E8-B48F-1D18A9856A87","last_name":"Cheung"},{"orcid":"0000-0003-2279-1061","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer","first_name":"Simon"}],"corr_author":"1","project":[{"grant_number":"T01031","_id":"268F8446-B435-11E9-9278-68D0E5697425","name":"Role of Eed in neural stem cell lineage progression","call_identifier":"FWF"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411"},{"name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805"},{"call_identifier":"H2020","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","_id":"260018B0-B435-11E9-9278-68D0E5697425","grant_number":"725780"}],"title":"Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry","abstract":[{"lang":"eng","text":"Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice and high-resolution phenotyping at the individual cell level. Here, we present a protocol for isolating MADM-labeled cells with high yield for downstream molecular analyses using fluorescence-activated cell sorting (FACS). We describe steps for generating MADM-labeled mice, perfusion, single-cell suspension, and debris removal. We then detail procedures for cell sorting by FACS and downstream analysis. This protocol is suitable for embryonic to adult mice.\r\nFor complete details on the use and execution of this protocol, please refer to Contreras et al. (2021).1"}],"status":"public","month":"03","volume":5,"article_processing_charge":"Yes (in subscription journal)","oa":1,"date_created":"2023-12-13T11:48:05Z","quality_controlled":"1","ddc":["570"],"article_number":"102771","article_type":"review","file_date_updated":"2024-07-16T11:50:03Z","publisher":"Elsevier","publication_identifier":{"issn":["2666-1667"]},"publication":"STAR Protocols","ec_funded":1},{"volume":63,"article_processing_charge":"Yes (via OA deal)","oa":1,"date_created":"2023-12-15T16:10:13Z","quality_controlled":"1","ddc":["540"],"article_number":"e202316476","file_date_updated":"2024-07-16T11:54:46Z","article_type":"review","publisher":"Wiley","abstract":[{"text":"The short history of research on Li-O2 batteries has seen a remarkable number of mechanistic U-turns over the years. From the initial use of carbonate electrolytes, that were then found to be entirely unsuitable, to the belief that (su)peroxide was solely responsible for degradation, before the more reactive singlet oxygen was found to form, to the hypothesis that capacity depends on a competing surface/solution mechanism before a practically exclusive solution mechanism was identified. Herein, we argue for an ever-fresh look at the reported data without bias towards supposedly established explanations. We explain how the latest findings on rate and capacity limits, as well as the origin of side reactions, are connected via the disproportionation (DISP) step in the (dis)charge mechanism. Therefrom, directions emerge for the design of electrolytes and mediators on how to suppress side reactions and to enable high rate and high reversible capacity.","lang":"eng"}],"status":"public","month":"07","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"publication":"Angewandte Chemie International Edition","ec_funded":1,"has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","related_material":{"record":[{"relation":"dissertation_contains","id":"20607","status":"public"}]},"scopus_import":"1","keyword":["General Chemistry","Catalysis"],"isi":1,"issue":"28","language":[{"iso":"eng"}],"acknowledgement":"S.A.F. is indebted to ISTA for support. R.B.J. thanks the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413 for funding. B.P. thanks Alistore ERI for providing a PhD scholarship.","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)"},"file":[{"date_updated":"2024-07-16T11:54:46Z","relation":"main_file","file_size":4766445,"content_type":"application/pdf","checksum":"fe2c23454279eb9d76ed6ca9970c21c7","file_name":"2024_AngChemieInt_Jethwa.pdf","date_created":"2024-07-16T11:54:46Z","creator":"dernst","access_level":"open_access","file_id":"17261","success":1}],"external_id":{"isi":["001241932700001"],"pmid":["38095355"]},"date_published":"2024-07-08T00:00:00Z","date_updated":"2026-04-07T12:27:23Z","doi":"10.1002/anie.202316476","day":"08","year":"2024","pmid":1,"citation":{"ieee":"R. B. Jethwa, S. Mondal, B. Pant, and S. A. Freunberger, “To DISP or not? The far‐reaching reaction mechanisms underpinning Lithium‐air batteries,” Angewandte Chemie International Edition, vol. 63, no. 28. Wiley, 2024.","apa":"Jethwa, R. B., Mondal, S., Pant, B., & Freunberger, S. A. (2024). To DISP or not? The far‐reaching reaction mechanisms underpinning Lithium‐air batteries. Angewandte Chemie International Edition. Wiley. https://doi.org/10.1002/anie.202316476","ama":"Jethwa RB, Mondal S, Pant B, Freunberger SA. To DISP or not? The far‐reaching reaction mechanisms underpinning Lithium‐air batteries. Angewandte Chemie International Edition. 2024;63(28). doi:10.1002/anie.202316476","ista":"Jethwa RB, Mondal S, Pant B, Freunberger SA. 2024. To DISP or not? The far‐reaching reaction mechanisms underpinning Lithium‐air batteries. Angewandte Chemie International Edition. 63(28), e202316476.","chicago":"Jethwa, Rajesh B, Soumyadip Mondal, Bhargavi Pant, and Stefan Alexander Freunberger. “To DISP or Not? The Far‐reaching Reaction Mechanisms Underpinning Lithium‐air Batteries.” Angewandte Chemie International Edition. Wiley, 2024. https://doi.org/10.1002/anie.202316476.","short":"R.B. Jethwa, S. Mondal, B. Pant, S.A. Freunberger, Angewandte Chemie International Edition 63 (2024).","mla":"Jethwa, Rajesh B., et al. “To DISP or Not? The Far‐reaching Reaction Mechanisms Underpinning Lithium‐air Batteries.” Angewandte Chemie International Edition, vol. 63, no. 28, e202316476, Wiley, 2024, doi:10.1002/anie.202316476."},"author":[{"first_name":"Rajesh B","id":"4cc538d5-803f-11ed-ab7e-8139573aad8f","last_name":"Jethwa","full_name":"Jethwa, Rajesh B","orcid":"0000-0002-0404-4356"},{"last_name":"Mondal","id":"d25d21ef-dc8d-11ea-abe3-ec4576307f48","first_name":"Soumyadip","full_name":"Mondal, Soumyadip"},{"id":"50c64d4d-eb97-11eb-a6c2-d33e5e14f112","last_name":"Pant","first_name":"Bhargavi","full_name":"Pant, Bhargavi"},{"orcid":"0000-0003-2902-5319","full_name":"Freunberger, Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","first_name":"Stefan Alexander"}],"publication_status":"published","corr_author":"1","project":[{"grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"title":"To DISP or not? The far‐reaching reaction mechanisms underpinning Lithium‐air batteries","_id":"14687","department":[{"_id":"StFr"},{"_id":"GradSch"}],"intvolume":" 63","type":"journal_article","oa_version":"Published Version"}]