--- APC_amount: 3197,23 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18481' abstract: - lang: eng text: A tight regulation of morphogen production is key for morphogen gradient formation and thereby for reproducible and organised organ development. Although many genetic interactions involved in the establishment of morphogen production domains are known, the biophysical mechanisms of morphogen source formation are poorly understood. Here we addressed this by focusing on the morphogen Sonic hedgehog (Shh) in the vertebrate neural tube. Shh is produced by the adjacently located notochord and by the floor plate of the neural tube. Using a data-constrained computational screen, we identified different possible mechanisms by which floor plate formation can occur, only one of which is consistent with experimental data. In this mechanism, the floor plate is established rapidly in response to Shh from the notochord and the dynamics of regulatory interactions within the neural tube. In this process, uniform activators and Shh-dependent repressors are key for establishing the floor plate size. Subsequently, the floor plate becomes insensitive to Shh and increases in size due to tissue growth, leading to scaling of the floor plate with neural tube size. In turn, this results in scaling of the Shh amplitude with tissue growth. Thus, this mechanism ensures a separation of time scales in floor plate formation, so that the floor plate domain becomes growth-dependent after an initial rapid establishment phase. Our study raises the possibility that the time scale separation between specification and growth might be a common strategy for scaling the morphogen gradient amplitude in growing organs. The model that we developed provides a new opportunity for quantitative studies of morphogen source formation in growing tissues. acknowledgement: "We thank Martina Greunz-Schindler for technical support, and Thomas Minchington and James Briscoe for comments on the manuscript.\r\nRDJGH, MM and MZ were supported by a grant from the Priority Research Area DigiWorld\r\nunder the Strategic Programme Excellence Initiative at Jagiellonian University. The research\r\nwas supported by the Polish National Agency for Academic Exchange, PN/PPO/2018/1/00011/U/00001 which paid the salary of MM and MZ up to Feb 2023. The research received support from National Science Center, Poland, 2021/42/E/NZ2/00188 which paid salary of MZ. Work in the AK labis supported by ISTA to KK and AK, the European\r\nResearch Council under Horizon Europe: grant 101044579 to AK, and Austrian Science Fund\r\n(FWF): Grant DOI 10.55776/F78 to AK. The salaries of AK and KK were paid by ISTA. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript." article_number: e1012508 article_processing_charge: No article_type: original author: - first_name: Richard D.J.G. full_name: Ho, Richard D.J.G. last_name: Ho - first_name: Kasumi full_name: Kishi, Kasumi id: 3065DFC4-F248-11E8-B48F-1D18A9856A87 last_name: Kishi orcid: 0000-0001-6060-4795 - first_name: Maciej full_name: Majka, Maciej last_name: Majka - first_name: Anna full_name: Kicheva, Anna id: 3959A2A0-F248-11E8-B48F-1D18A9856A87 last_name: Kicheva orcid: 0000-0003-4509-4998 - first_name: Marcin P full_name: Zagórski, Marcin P id: 343DA0DC-F248-11E8-B48F-1D18A9856A87 last_name: Zagórski orcid: 0000-0001-7896-7762 citation: ama: Ho RDJG, Kishi K, Majka M, Kicheva A, Zagórski MP. Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. 2024;20. doi:10.1371/journal.pcbi.1012508 apa: Ho, R. D. J. G., Kishi, K., Majka, M., Kicheva, A., & Zagórski, M. P. (2024). Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1012508 chicago: Ho, Richard D.J.G., Kasumi Kishi, Maciej Majka, Anna Kicheva, and Marcin P Zagórski. “Dynamics of Morphogen Source Formation in a Growing Tissue.” PLoS Computational Biology. Public Library of Science, 2024. https://doi.org/10.1371/journal.pcbi.1012508. ieee: R. D. J. G. Ho, K. Kishi, M. Majka, A. Kicheva, and M. P. Zagórski, “Dynamics of morphogen source formation in a growing tissue,” PLoS Computational Biology, vol. 20. Public Library of Science, 2024. ista: Ho RDJG, Kishi K, Majka M, Kicheva A, Zagórski MP. 2024. Dynamics of morphogen source formation in a growing tissue. PLoS Computational Biology. 20, e1012508. mla: Ho, Richard D. J. G., et al. “Dynamics of Morphogen Source Formation in a Growing Tissue.” PLoS Computational Biology, vol. 20, e1012508, Public Library of Science, 2024, doi:10.1371/journal.pcbi.1012508. short: R.D.J.G. Ho, K. Kishi, M. Majka, A. Kicheva, M.P. Zagórski, PLoS Computational Biology 20 (2024). corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-10-14T00:00:00Z date_updated: 2026-04-07T12:31:58Z day: '14' ddc: - '570' department: - _id: AnKi doi: 10.1371/journal.pcbi.1012508 external_id: isi: - '001331700300003' pmid: - '39401260' file: - access_level: open_access checksum: 42fa714459943cb3961b40fab8fd82c8 content_type: application/pdf creator: dernst date_created: 2024-10-29T11:59:09Z date_updated: 2024-10-29T11:59:09Z file_id: '18487' file_name: 2024_PloSComBio_Ho.pdf file_size: 3732443 relation: main_file success: 1 file_date_updated: 2024-10-29T11:59:09Z has_accepted_license: '1' intvolume: ' 20' isi: 1 language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: bd7e737f-d553-11ed-ba76-d69ffb5ee3aa grant_number: '101044579' name: Mechanisms of tissue size regulation in spinal cord development - _id: 059DF620-7A3F-11EA-A408-12923DDC885E grant_number: F7802 name: Stem Cell Modulation in Neural Development and Regeneration/ P02-Morphogen control of growth and pattern in the spinal cord publication: PLoS Computational Biology publication_identifier: eissn: - 1553-7358 issn: - 1553-734X publication_status: published publisher: Public Library of Science quality_controlled: '1' related_material: record: - id: '20393' relation: dissertation_contains status: public scopus_import: '1' status: public title: Dynamics of morphogen source formation in a growing tissue tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 20 year: '2024' ... --- OA_type: closed access _id: '18482' abstract: - lang: eng text: "This paper is dedicated to an optimization problem. Let A, B ⊂ Rn be compact convex sets. Consider the minimal number t0 > 0 such that t0B covers A after a shift to a vector x0 ∈ \r\nRn. The goal is to find t0 and x0. In the special case of B being a unit ball centered at zero, x0 and t0 are known as the Chebyshev center and the Chebyshev radius of A. This paper focuses on the case in which A and B are defined with their black-box support functions. An algorithm for solving such problems efficiently is suggested. The algorithm has a superlinear convergence rate, and it can solve hundred-dimensional test problems in a reasonable time, but some additional conditions on A and B are required to guarantee the presence of convergence. Additionally, the behavior of the algorithm for a simple special case is investigated, which leads to a number of theoretical results. Perturbations of this special case are also studied." acknowledgement: The author is grateful to Maxim Balashov for setting the problem, providing useful literature, important discussions and text review. Also, I thank Dmitry Tsarev and Kseniia Petukhova for meaningful talks and support. article_processing_charge: No article_type: original author: - first_name: Pavel full_name: Arkhipov, Pavel id: b25f2ab2-1fed-11ee-8599-fe02d211784f last_name: Arkhipov citation: ama: Arkhipov P. An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. 2024;85(6):522-532. doi:10.1134/S0005117924060031 apa: Arkhipov, P. (2024). An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. Springer Nature. https://doi.org/10.1134/S0005117924060031 chicago: Arkhipov, Pavel. “An Algorithm for Finding the Generalized Chebyshev Center of Sets Defined via Their Support Functions.” Automation and Remote Control. Springer Nature, 2024. https://doi.org/10.1134/S0005117924060031. ieee: P. Arkhipov, “An algorithm for finding the generalized Chebyshev center of sets defined via their support functions,” Automation and Remote Control, vol. 85, no. 6. Springer Nature, pp. 522–532, 2024. ista: Arkhipov P. 2024. An algorithm for finding the generalized Chebyshev center of sets defined via their support functions. Automation and Remote Control. 85(6), 522–532. mla: Arkhipov, Pavel. “An Algorithm for Finding the Generalized Chebyshev Center of Sets Defined via Their Support Functions.” Automation and Remote Control, vol. 85, no. 6, Springer Nature, 2024, pp. 522–32, doi:10.1134/S0005117924060031. short: P. Arkhipov, Automation and Remote Control 85 (2024) 522–532. corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-06-01T00:00:00Z date_updated: 2025-09-08T14:27:08Z day: '01' department: - _id: GradSch doi: 10.1134/S0005117924060031 external_id: isi: - '001338721700007' intvolume: ' 85' isi: 1 issue: '6' language: - iso: eng month: '06' oa_version: None page: 522-532 publication: Automation and Remote Control publication_identifier: eissn: - 1608-3032 issn: - 0005-1179 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: An algorithm for finding the generalized Chebyshev center of sets defined via their support functions type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 85 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18483' abstract: - lang: eng text: In this paper we prove a perturbative version of a remarkable Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) result. They prove non perturbative Birkhoff conjecture for centrally-symmetric convex domains, namely, a centrally-symmetric convex domain with integrable billiard is ellipse. We combine techniques from Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) with a local result by Kaloshin–Sorrentino (Ann. Math. 188(1):315–380, 2018) and show that a domain close enough to a centrally symmetric one with integrable billiard is ellipse. To combine these results we derive a slight extension of Bialy–Mironov (Ann. Math. 196(1):389–413, 2022) by proving that a notion of rational integrability is equivalent to the C0-integrability condition used in their paper. acknowledgement: We are grateful to the anonymous referee for their careful reading and valuable remarks and comments which helped to improve significantly the paper. Open access funding provided by Institute of Science and Technology (IST Austria). V.K. and C.E.K. gratefully acknowledge support from the European Research Council (ERC) through the Advanced Grant “SPERIG” (#885 707). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Vadim full_name: Kaloshin, Vadim id: FE553552-CDE8-11E9-B324-C0EBE5697425 last_name: Kaloshin orcid: 0000-0002-6051-2628 - first_name: Edmond full_name: Koudjinan, Edmond id: 52DF3E68-AEFA-11EA-95A4-124A3DDC885E last_name: Koudjinan orcid: 0000-0003-2640-4049 - first_name: Ke full_name: Zhang, Ke last_name: Zhang citation: ama: Kaloshin V, Koudjinan E, Zhang K. Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. 2024;34:1973-2007. doi:10.1007/s00039-024-00695-6 apa: Kaloshin, V., Koudjinan, E., & Zhang, K. (2024). Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. Springer Nature. https://doi.org/10.1007/s00039-024-00695-6 chicago: Kaloshin, Vadim, Edmond Koudjinan, and Ke Zhang. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” Geometric and Functional Analysis. Springer Nature, 2024. https://doi.org/10.1007/s00039-024-00695-6. ieee: V. Kaloshin, E. Koudjinan, and K. Zhang, “Birkhoff conjecture for nearly centrally symmetric domains,” Geometric and Functional Analysis, vol. 34. Springer Nature, pp. 1973–2007, 2024. ista: Kaloshin V, Koudjinan E, Zhang K. 2024. Birkhoff conjecture for nearly centrally symmetric domains. Geometric and Functional Analysis. 34, 1973–2007. mla: Kaloshin, Vadim, et al. “Birkhoff Conjecture for Nearly Centrally Symmetric Domains.” Geometric and Functional Analysis, vol. 34, Springer Nature, 2024, pp. 1973–2007, doi:10.1007/s00039-024-00695-6. short: V. Kaloshin, E. Koudjinan, K. Zhang, Geometric and Functional Analysis 34 (2024) 1973–2007. corr_author: '1' date_created: 2024-10-27T23:01:45Z date_published: 2024-12-01T00:00:00Z date_updated: 2025-09-08T14:27:45Z day: '01' ddc: - '510' department: - _id: VaKa doi: 10.1007/s00039-024-00695-6 ec_funded: 1 external_id: arxiv: - '2306.12301' isi: - '001329804200001' file: - access_level: open_access checksum: e7fcd9f78beb40408c7d858ac0625e27 content_type: application/pdf creator: dernst date_created: 2025-01-13T09:14:24Z date_updated: 2025-01-13T09:14:24Z file_id: '18833' file_name: 2024_GeometricFunctionalAnalysis_Kaloshin.pdf file_size: 2260980 relation: main_file success: 1 file_date_updated: 2025-01-13T09:14:24Z has_accepted_license: '1' intvolume: ' 34' isi: 1 language: - iso: eng month: '12' oa: 1 oa_version: Published Version page: 1973-2007 project: - _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A call_identifier: H2020 grant_number: '885707' name: Spectral rigidity and integrability for billiards and geodesic flows publication: Geometric and Functional Analysis publication_identifier: eissn: - 1420-8970 issn: - 1016-443X publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Birkhoff conjecture for nearly centrally symmetric domains tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 34 year: '2024' ... --- APC_amount: 3711,01 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18488' abstract: - lang: eng text: The advancement of quantum simulators motivates the development of a theoretical framework to assist with efficient state preparation in quantum many-body systems. Generally, preparing a target entangled state via unitary evolution with time-dependent couplings is a challenging task and very little is known about the existence of solutions and their properties. In this work we develop a constructive approach for preparing matrix product states (MPS) via continuous unitary evolution. We provide an explicit construction of the operator that exactly implements the evolution of a given MPS along a specified direction in its tangent space. This operator can be written as a sum of local terms of finite range, yet it is in general non-Hermitian. Relying on the explicit construction of the non-Hermitian generator of the dynamics, we demonstrate the existence of a Hermitian sequence of operators that implements the desired MPS evolution with an error that decreases exponentially with the operator range. The construction is benchmarked on an explicit periodic trajectory in a translationally invariant MPS manifold. We demonstrate that the Floquet unitary generating the dynamics over one period of the trajectory features an approximate MPS-like eigenstate embedded among a sea of thermalizing eigenstates. These results show that our construction is not only useful for state preparation and control of many-body systems, but also provides a generic route towards Floquet scars—periodically driven models with quasilocal generators of dynamics that have exact MPS eigenstates in their spectrum. acknowledgement: We thank L. Piroli, S. Garratt, and A. Molnár for insightful discussions. This research was funded in part by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreements No. 850899 and No. 863476), the Austrian Science Fund (FWF) (Grant DOIs 10.55776/COE1, 10.55776/P36305, and 10.55776/F71), and the European Union (NextGenerationEU). This work was performed in part at the Aspen Center for Physics, which is supported by National Science Foundation Grant PHY-2210452. This research was supported in part by NSF Grant PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP). article_number: '040311' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: Marko full_name: Ljubotina, Marko id: F75EE9BE-5C90-11EA-905D-16643DDC885E last_name: Ljubotina orcid: 0000-0003-0038-7068 - first_name: Elena full_name: Petrova, Elena id: 0ac84990-897b-11ed-a09c-f5abb56a4ede last_name: Petrova - first_name: Norbert full_name: Schuch, Norbert last_name: Schuch - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 citation: ama: Ljubotina M, Petrova E, Schuch N, Serbyn M. Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. 2024;5(4). doi:10.1103/prxquantum.5.040311 apa: Ljubotina, M., Petrova, E., Schuch, N., & Serbyn, M. (2024). Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. American Physical Society. https://doi.org/10.1103/prxquantum.5.040311 chicago: Ljubotina, Marko, Elena Petrova, Norbert Schuch, and Maksym Serbyn. “Tangent Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX Quantum. American Physical Society, 2024. https://doi.org/10.1103/prxquantum.5.040311. ieee: M. Ljubotina, E. Petrova, N. Schuch, and M. Serbyn, “Tangent space generators of matrix product states and exact floquet quantum scars,” PRX Quantum, vol. 5, no. 4. American Physical Society, 2024. ista: Ljubotina M, Petrova E, Schuch N, Serbyn M. 2024. Tangent space generators of matrix product states and exact floquet quantum scars. PRX Quantum. 5(4), 040311. mla: Ljubotina, Marko, et al. “Tangent Space Generators of Matrix Product States and Exact Floquet Quantum Scars.” PRX Quantum, vol. 5, no. 4, 040311, American Physical Society, 2024, doi:10.1103/prxquantum.5.040311. short: M. Ljubotina, E. Petrova, N. Schuch, M. Serbyn, PRX Quantum 5 (2024). corr_author: '1' date_created: 2024-10-29T16:04:05Z date_published: 2024-10-23T00:00:00Z date_updated: 2025-09-08T14:26:29Z day: '23' ddc: - '530' department: - _id: MaSe doi: 10.1103/prxquantum.5.040311 ec_funded: 1 external_id: arxiv: - '2403.12325' isi: - '001346198800001' file: - access_level: open_access checksum: 2e057ba021744d0a74602517935326b3 content_type: application/pdf creator: dernst date_created: 2024-10-30T08:59:09Z date_updated: 2024-10-30T08:59:09Z file_id: '18489' file_name: 2024_PRXQuantum_Ljubotina.pdf file_size: 1151431 relation: main_file success: 1 file_date_updated: 2024-10-30T08:59:09Z has_accepted_license: '1' intvolume: ' 5' isi: 1 issue: '4' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: PRX Quantum publication_identifier: eissn: - 2691-3399 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: Tangent space generators of matrix product states and exact floquet quantum scars tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 5 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18490' abstract: - lang: eng text: 'For large classes of even-dimensional Riemannian manifolds (Formula presented.), we construct and analyze conformally invariant random fields. These centered Gaussian fields (Formula presented.), called co-polyharmonic Gaussian fields, are characterized by their covariance kernels k which exhibit a precise logarithmic divergence: (Formula presented.). They share a fundamental quasi-invariance property under conformal transformations. In terms of the co-polyharmonic Gaussian field (Formula presented.), we define the Liouville Quantum Gravity measure, a random measure on (Formula presented.), heuristically given as (Formula presented.) and rigorously obtained as almost sure weak limit of the right-hand side with (Formula presented.) replaced by suitable regular approximations (Formula presented.). In terms on the Liouville Quantum Gravity measure, we define the Liouville Brownian motion on (Formula presented.) and the random GJMS operators. Finally, we present an approach to a conformal field theory in arbitrary even dimension with an ansatz based on Branson''s (Formula presented.) -curvature: we give a rigorous meaning to the Polyakov–Liouville measure (Formula presented.) and we derive the corresponding conformal anomaly. The set of admissible manifolds is conformally invariant. It includes all compact 2-dimensional Riemannian manifolds, all compact non-negatively curved Einstein manifolds of even dimension, and large classes of compact hyperbolic manifolds of even dimension. However, not every compact even-dimensional Riemannian manifold is admissible. Our results concerning the logarithmic divergence of the kernel (Formula presented.) rely on new sharp estimates for heat kernels and higher order Green kernels on arbitrary closed manifolds. ' acknowledgement: The authors are grateful to Masha Gordina for helpful references, and to Nathanaël Berestycki, Baptiste Cerclé, and Ewain Gwynne for valuable comments on the first circulated version of this paper. They also would like to thank Sebastian Andres, Peter Friz, and Yizheng Yuan for pointing out an erroneous formulation in the previous version of Theorem 5.7. Moreover, KTS would liketo express his thanks to Sebastian Andres, Matthias Erbar, Martin Huesmann, and Jan Mass for stimulating discussions on previous attempts to this project. LDS gratefully acknowledges financial support from the European Research Council (grant agreement No 716117, awarded to J. Maas), from the Austrian Science Fund (FWF) project 10.55776/ESP208, and from the Austrian Science Fund (FWF) project 10.55776/F65.RH, EK, and KTS gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the project “Random Riemannian Geometry” within the SPP 2265 “Random Geomet-ric Systems,” through the Hausdorff Center for Mathematics (project ID 390685813), and through project B03 within the CRC 1060 (project ID 211504053). RH and KTS also gratefully acknowledge financial support from the European Research Council through the ERC AdG “RicciBounds”(grant agreement 694405).Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. Open access funding enabled and organized by Projekt DEAL. article_number: e70003 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lorenzo full_name: Dello Schiavo, Lorenzo id: ECEBF480-9E4F-11EA-B557-B0823DDC885E last_name: Dello Schiavo orcid: 0000-0002-9881-6870 - first_name: Ronan full_name: Herry, Ronan last_name: Herry - first_name: Eva full_name: Kopfer, Eva last_name: Kopfer - first_name: Karl Theodor full_name: Sturm, Karl Theodor last_name: Sturm citation: ama: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. 2024;110(5). doi:10.1112/jlms.70003 apa: Dello Schiavo, L., Herry, R., Kopfer, E., & Sturm, K. T. (2024). Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. London Mathematical Society. https://doi.org/10.1112/jlms.70003 chicago: Dello Schiavo, Lorenzo, Ronan Herry, Eva Kopfer, and Karl Theodor Sturm. “Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal of the London Mathematical Society. London Mathematical Society, 2024. https://doi.org/10.1112/jlms.70003. ieee: L. Dello Schiavo, R. Herry, E. Kopfer, and K. T. Sturm, “Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension,” Journal of the London Mathematical Society, vol. 110, no. 5. London Mathematical Society, 2024. ista: Dello Schiavo L, Herry R, Kopfer E, Sturm KT. 2024. Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension. Journal of the London Mathematical Society. 110(5), e70003. mla: Dello Schiavo, Lorenzo, et al. “Conformally Invariant Random Fields, Liouville Quantum Gravity Measures, and Random Paneitz Operators on Riemannian Manifolds of Even Dimension.” Journal of the London Mathematical Society, vol. 110, no. 5, e70003, London Mathematical Society, 2024, doi:10.1112/jlms.70003. short: L. Dello Schiavo, R. Herry, E. Kopfer, K.T. Sturm, Journal of the London Mathematical Society 110 (2024). date_created: 2024-11-03T23:01:44Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:29:45Z day: '01' ddc: - '510' department: - _id: JaMa doi: 10.1112/jlms.70003 ec_funded: 1 external_id: isi: - '001351918100029' file: - access_level: open_access checksum: 143816823b5f43bd3748da8e3e91cef5 content_type: application/pdf creator: dernst date_created: 2024-11-04T08:54:26Z date_updated: 2024-11-04T08:54:26Z file_id: '18497' file_name: 2024_JourLondonMathSoc_Schiavo.pdf file_size: 911476 relation: main_file success: 1 file_date_updated: 2024-11-04T08:54:26Z has_accepted_license: '1' intvolume: ' 110' isi: 1 issue: '5' language: - iso: eng month: '11' oa: 1 oa_version: Published Version project: - _id: 256E75B8-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '716117' name: Optimal Transport and Stochastic Dynamics - _id: 34dbf174-11ca-11ed-8bc3-afe9d43d4b9c grant_number: E208 name: Configuration Spaces over Non-Smooth Spaces - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Journal of the London Mathematical Society publication_identifier: eissn: - 1469-7750 issn: - 0024-6107 publication_status: published publisher: London Mathematical Society quality_controlled: '1' scopus_import: '1' status: public title: Conformally invariant random fields, Liouville quantum gravity measures, and random Paneitz operators on Riemannian manifolds of even dimension tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 110 year: '2024' ... --- APC_amount: 4569,23 EUR DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '18491' abstract: - lang: eng text: Predicting the outcomes of adaptation is a major goal of evolutionary biology. When temporal changes in the environment mirror spatial gradients, it opens up the potential for predicting the course of adaptive evolution over time based on patterns of spatial genetic and phenotypic variation. We assessed this approach in a 30-year transplant experiment in the intertidal snail Littorina saxatilis. In 1992, snails were transplanted from a predation-dominated environment to one dominated by wave action. On the basis of spatial patterns, we predicted transitions in shell size and morphology, allele frequencies at positions throughout the genome, and chromosomal rearrangement frequencies. Observed changes closely agreed with predictions and transformation was both dramatic and rapid. Hence, adaptation can be predicted from knowledge of the phenotypic and genetic variation among populations. acknowledgement: 'This work was received funding from the following: Norwegian Research Council RCN project 315287 (A.M.W.), Swedish Research Council 2021-04191 (K.J.), European Research Council grant 101055327 HaplotypeStructure (N.B.), Austrian Science Fund FWF; P 32166-B32 Snapdragon Speciation (N.B.), European Research Council (R.B.), and Portuguese Foundation for Science and Technology FCT: 2020.00275.CEECIND and PTDC/BIA-EVL/1614/2021 (R.F.).' article_number: eadp2102 article_processing_charge: Yes article_type: original author: - first_name: Diego Fernando full_name: Garcia Castillo, Diego Fernando id: ae681a14-dc74-11ea-a0a7-c6ef18161701 last_name: Garcia Castillo - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Rui full_name: Faria, Rui last_name: Faria - first_name: Jenny full_name: Larsson, Jenny last_name: Larsson - first_name: Sean full_name: Stankowski, Sean id: 43161670-5719-11EA-8025-FABC3DDC885E last_name: Stankowski - first_name: Roger full_name: Butlin, Roger last_name: Butlin - first_name: Kerstin full_name: Johannesson, Kerstin last_name: Johannesson - first_name: Anja M full_name: Westram, Anja M id: 3C147470-F248-11E8-B48F-1D18A9856A87 last_name: Westram orcid: 0000-0003-1050-4969 citation: ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. 2024;10(41). doi:10.1126/sciadv.adp2102' apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski, S., Butlin, R., … Westram, A. M. (2024). Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. AAAS. https://doi.org/10.1126/sciadv.adp2102' chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson, Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Science Advances. AAAS, 2024. https://doi.org/10.1126/sciadv.adp2102.' ieee: 'D. F. Garcia Castillo et al., “Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails,” Science Advances, vol. 10, no. 41. AAAS, 2024.' ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R, Johannesson K, Westram AM. 2024. Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails. Science Advances. 10(41), eadp2102.' mla: 'Garcia Castillo, Diego Fernando, et al. “Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Science Advances, vol. 10, no. 41, eadp2102, AAAS, 2024, doi:10.1126/sciadv.adp2102.' short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R. Butlin, K. Johannesson, A.M. Westram, Science Advances 10 (2024). corr_author: '1' date_created: 2024-11-03T23:01:44Z date_published: 2024-10-11T00:00:00Z date_updated: 2026-04-07T11:42:09Z day: '11' ddc: - '570' department: - _id: NiBa doi: 10.1126/sciadv.adp2102 external_id: isi: - '001354405400018' file: - access_level: open_access checksum: 96aa0d3640fa9401975138e59054f84e content_type: application/pdf creator: dernst date_created: 2024-11-04T09:35:49Z date_updated: 2024-11-04T09:35:49Z file_id: '18499' file_name: 2024_ScienceAdv_Castillo.pdf file_size: 1154107 relation: main_file success: 1 file_date_updated: 2024-11-04T09:35:49Z has_accepted_license: '1' intvolume: ' 10' isi: 1 issue: '41' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: bd6958e0-d553-11ed-ba76-86eba6a76c00 grant_number: '101055327' name: Understanding the evolution of continuous genomes - _id: 05959E1C-7A3F-11EA-A408-12923DDC885E grant_number: P32166 name: Snapdragon Speciation - _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1 call_identifier: FWF name: FWF Open Access Fund publication: Science Advances publication_identifier: eissn: - 2375-2548 publication_status: published publisher: AAAS quality_controlled: '1' related_material: link: - relation: software url: https://github.com/fernandoGarcia21/littorina_saxatilis_skerry record: - id: '18498' relation: research_data status: public - id: '20991' relation: dissertation_contains status: public scopus_import: '1' status: public title: 'Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 10 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18492' abstract: - lang: eng text: 'Surveys in the Milky Way and Large Magellanic Cloud have revealed that the majority of massive stars will interact with companions during their lives. However, knowledge of the binary properties of massive stars at low metallicity, and therefore in conditions approaching those of the Early Universe, remain sparse. We present the Binarity at LOw Metallicity (BLOeM) campaign, an ESO large programme designed to obtain 25 epochs of spectroscopy for 929 massive stars in the Small Magellanic Cloud, allowing us to probe multiplicity in the lowest-metallicity conditions to date (Z = 0.2 Z⊙). BLOeM will provide (i) the binary fraction, (ii) the orbital configurations of systems with periods of P ≲ 3 yr, (iii) dormant black-hole binary candidates (OB+BH), and (iv) a legacy database of physical parameters of massive stars at low metallicity. Main sequence (OB-type) and evolved (OBAF-type) massive stars are observed with the LR02 setup of the GIRAFFE instrument of the Very Large Telescope (3960–4570 Å resolving power R = 6200; typical signal-to-noise ratio(S/N) ≈70–100). This paper utilises the first nine epochs obtained over a three-month time period. We describe the survey and data reduction, perform a spectral classification of the stacked spectra, and construct a Hertzsprung-Russell diagram of the sample via spectral-type and photometric calibrations. Our detailed classification reveals that the sample covers spectral types from O4 to F5, spanning the effective temperature and luminosity ranges 6.5 ≲ Teff/kK ≲ 45 and 3.7 < log L/L⊙ < 6.1 and initial masses of 8 ≲ Mini ≲ 80 M⊙. The sample comprises 159 O-type stars, 331 early B-type (B0–3) dwarfs and giants (luminosity classes V–III), 303 early B-type supergiants (II–I), and 136 late-type BAF supergiants. At least 82 stars are OBe stars: 20 O-type and 62 B-type (13% and 11% of the respective samples). In addition, the sample includes 4 high-mass X-ray binaries, 3 stars resembling luminous blue variables, 2 bloated stripped-star candidates, 2 candidate magnetic stars, and 74 eclipsing binaries.' acknowledgement: 'The research leading to these results has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement numbers 772225: MULTIPLES). PAC and JMB are supported by the Science and Technology Facilities Council research grant ST/V000853/1 (PI. V. Dhillon). DMB gratefully acknowledges support from UK Research and Innovation (UKRI) in the form of a Frontier Research grant under the UK government’s ERC Horizon Europe funding guarantee (SYMPHONY; PI Bowman; grant number: EP/Y031059/1), and a Royal Society University Research Fellowship (PI Bowman; grant number: URF\R1\231631). ZK acknowledges support from JSPS Kakenhi Grant-in-Aid for Scientific Research (23K19071). IM acknowledges support from the Australian Research Council (ARC) Centre of Excellence for Gravitational Wave Discovery (OzGrav), through project number CE230100016. AACS, VR, RRL, and MBP are funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) in the form of an Emmy Noether Research Group – Project-ID 445674056 (SA4064/1-1, PI Sander). GGT and JJ are supported by the German Deutsche Forschungsgemeinschaft (DFG) under Project-ID 496854903 (SA4064/2-1, PI Sander) VR, GGT, and AACS further acknowledge support from the Federal Ministry of Education and Research (BMBF) and the Baden-Württemberg Ministry of Science as part of the Excellence Strategy of the German Federal and State Governments. ECS acknowledges financial support by the Federal Ministry for Economic Affairs and Climate Action (BMWK) via the German Aerospace Center (Deutsches Zentrum für Luft- und Raumfahrt, DLR) grant 50 OR 2306 (PI: Ramachandran/Sander). This work has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 945806) and is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy EXC 2181/1-390900948 (the Heidelberg STRUCTURES Excellence Cluster). LMO is thankful for the funding provided by the DFG grant 443790621. This paper benefited from discussions at the International Space Science Institute (ISSI) in Bern through ISSI International Team project 512 (Multiwavelength View on Massive Stars in the Era of Multimessenger Astronomy). DP acknowledges financial support by the Deutsches Zentrum für Luft und Raumfahrt (DLR) grant FKZ 50OR2005. JIV acknowledges the European Research Council for support from the ERC Advanced grant ERC-2021-ADG101054731. JSV is supported by STFC (Science and Technology Facilities Council) funding under grant number ST/V000233/1. GH, SS-D, SRB and AH acknowledge support from the State Research Agency (AEI) of the Spanish Ministry of Science and Innovation (MICIN) and the European Regional Development Fund, FEDER under grants PID2021-122397NB-C21 and CEX2019-000920-S. SRB also acknowledges financial support by NextGeneration EU/PRTR and MIU (UNI/551/2021) through grant Margarita Salas-ULL. DFR is thankful for the support of the CAPES-Br and FAPERJ/DSC-10 (SEI-260003/001630/2023). F.N., and L.R.P. acknowledge support by grants PID2019-105552RB-C41 and PID2022-137779OB-C41 funded by MCIN/AEI/10.13039/501100011033 by “ERDF A way of making Europe”. MG acknowledges financial support from the grants PID2021-125485NB-C22, CEX2019-000918-M funded by MCIN/AEI/10.13039/501100011033 (State Agency for Research of the Spanish Ministry of Science and Innovation) and SGR-2021-01069 (AGAUR). GM acknowledges funding support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 772086). JMA acknowledges support from the Spanish Government Ministerio de Ciencia e Innovación and Agencia Estatal de Investigación (10.13 039/501 100 011 033) through grant PID2022-136640 NB-C22 and from the Consejo Superior de Investigaciones Científicas (CSIC) through grant 2022-AEP 005. MP is supported by the BEKKER fellowship BPN/BEK/2022/1/00106 from the Polish National Agency for Academic Exchange. KS is funded by the National Science Center (NCN), Poland, under grant number OPUS 2021/41/B/ST9/00757. JM acknowledges support from a Royal Society-Science Foundation Ireland University Research Fellowship. SJ acknowledges support from the FWO PhD fellowship under project 11E1721N. FB acknowledges the support of the European Research Council (ERC) Horizon Europe under grant agreement number 101044048.' article_number: A289 article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: T. full_name: Shenar, T. last_name: Shenar - first_name: J. full_name: Bodensteiner, J. last_name: Bodensteiner - first_name: H. full_name: Sana, H. last_name: Sana - first_name: P. A. full_name: Crowther, P. A. last_name: Crowther - first_name: D. J. full_name: Lennon, D. J. last_name: Lennon - first_name: M. full_name: Abdul-Masih, M. last_name: Abdul-Masih - first_name: L. A. full_name: Almeida, L. A. last_name: Almeida - first_name: F. full_name: Backs, F. last_name: Backs - first_name: S. R. full_name: Berlanas, S. R. last_name: Berlanas - first_name: M. full_name: Bernini-Peron, M. last_name: Bernini-Peron - first_name: J. M. full_name: Bestenlehner, J. M. last_name: Bestenlehner - first_name: D. M. full_name: Bowman, D. M. last_name: Bowman - first_name: V. A. full_name: Bronner, V. A. last_name: Bronner - first_name: N. full_name: Britavskiy, N. last_name: Britavskiy - first_name: A. full_name: De Koter, A. last_name: De Koter - first_name: S. E. full_name: De Mink, S. E. last_name: De Mink - first_name: K. full_name: Deshmukh, K. last_name: Deshmukh - first_name: C. J. full_name: Evans, C. J. last_name: Evans - first_name: M. full_name: Fabry, M. last_name: Fabry - first_name: M. full_name: Gieles, M. last_name: Gieles - first_name: A. full_name: Gilkis, A. last_name: Gilkis - first_name: G. full_name: González-Torà, G. last_name: González-Torà - first_name: G. full_name: Gräfener, G. last_name: Gräfener - first_name: Ylva Louise Linsdotter full_name: Götberg, Ylva Louise Linsdotter id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d last_name: Götberg orcid: 0000-0002-6960-6911 - first_name: C. full_name: Hawcroft, C. last_name: Hawcroft - first_name: V. full_name: Hénault-Brunet, V. last_name: Hénault-Brunet - first_name: A. full_name: Herrero, A. last_name: Herrero - first_name: G. full_name: Holgado, G. last_name: Holgado - first_name: S. full_name: Janssens, S. last_name: Janssens - first_name: C. full_name: Johnston, C. last_name: Johnston - first_name: J. full_name: Josiek, J. last_name: Josiek - first_name: S. full_name: Justham, S. last_name: Justham - first_name: V. M. full_name: Kalari, V. M. last_name: Kalari - first_name: Z. Z. full_name: Katabi, Z. Z. last_name: Katabi - first_name: Z. full_name: Keszthelyi, Z. last_name: Keszthelyi - first_name: J. full_name: Klencki, J. last_name: Klencki - first_name: J. full_name: Kubát, J. last_name: Kubát - first_name: B. full_name: Kubátová, B. last_name: Kubátová - first_name: N. full_name: Langer, N. last_name: Langer - first_name: R. R. full_name: Lefever, R. R. last_name: Lefever - first_name: B. full_name: Ludwig, B. last_name: Ludwig - first_name: J. full_name: Mackey, J. last_name: Mackey - first_name: L. full_name: Mahy, L. last_name: Mahy - first_name: J. full_name: Maíz Apellániz, J. last_name: Maíz Apellániz - first_name: I. full_name: Mandel, I. last_name: Mandel - first_name: G. full_name: Maravelias, G. last_name: Maravelias - first_name: P. full_name: Marchant, P. last_name: Marchant - first_name: A. full_name: Menon, A. last_name: Menon - first_name: F. full_name: Najarro, F. last_name: Najarro - first_name: L. M. full_name: Oskinova, L. M. last_name: Oskinova - first_name: A. J.G. full_name: O'Grady, A. J.G. last_name: O'Grady - first_name: R. full_name: Ovadia, R. last_name: Ovadia - first_name: L. R. full_name: Patrick, L. R. last_name: Patrick - first_name: D. full_name: Pauli, D. last_name: Pauli - first_name: M. full_name: Pawlak, M. last_name: Pawlak - first_name: V. full_name: Ramachandran, V. last_name: Ramachandran - first_name: M. full_name: Renzo, M. last_name: Renzo - first_name: D. F. full_name: Rocha, D. F. last_name: Rocha - first_name: A. A.C. full_name: Sander, A. A.C. last_name: Sander - first_name: T. full_name: Sayada, T. last_name: Sayada - first_name: F. R.N. full_name: Schneider, F. R.N. last_name: Schneider - first_name: A. full_name: Schootemeijer, A. last_name: Schootemeijer - first_name: E. C. full_name: Schösser, E. C. last_name: Schösser - first_name: C. full_name: Schürmann, C. last_name: Schürmann - first_name: K. full_name: Sen, K. last_name: Sen - first_name: S. full_name: Shahaf, S. last_name: Shahaf - first_name: S. full_name: Simón-Díaz, S. last_name: Simón-Díaz - first_name: M. full_name: Stoop, M. last_name: Stoop - first_name: S. full_name: Toonen, S. last_name: Toonen - first_name: F. full_name: Tramper, F. last_name: Tramper - first_name: J. Th full_name: Van Loon, J. Th last_name: Van Loon - first_name: R. full_name: Valli, R. last_name: Valli - first_name: L. A.C. full_name: Van Son, L. A.C. last_name: Van Son - first_name: A. full_name: Vigna-Gómez, A. last_name: Vigna-Gómez - first_name: J. I. full_name: Villaseñor, J. I. last_name: Villaseñor - first_name: J. S. full_name: Vink, J. S. last_name: Vink - first_name: C. full_name: Wang, C. last_name: Wang - first_name: R. full_name: Willcox, R. last_name: Willcox citation: ama: 'Shenar T, Bodensteiner J, Sana H, et al. Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC. Astronomy and Astrophysics. 2024;690. doi:10.1051/0004-6361/202451586' apa: 'Shenar, T., Bodensteiner, J., Sana, H., Crowther, P. A., Lennon, D. J., Abdul-Masih, M., … Willcox, R. (2024). Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202451586' chicago: 'Shenar, T., J. Bodensteiner, H. Sana, P. A. Crowther, D. J. Lennon, M. Abdul-Masih, L. A. Almeida, et al. “Binarity at LOw Metallicity (BLOeM): A Spectroscopic VLT Monitoring Survey of Massive Stars in the SMC.” Astronomy and Astrophysics. EDP Sciences, 2024. https://doi.org/10.1051/0004-6361/202451586.' ieee: 'T. Shenar et al., “Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC,” Astronomy and Astrophysics, vol. 690. EDP Sciences, 2024.' ista: 'Shenar T, Bodensteiner J, Sana H, Crowther PA, Lennon DJ, Abdul-Masih M, Almeida LA, Backs F, Berlanas SR, Bernini-Peron M, Bestenlehner JM, Bowman DM, Bronner VA, Britavskiy N, De Koter A, De Mink SE, Deshmukh K, Evans CJ, Fabry M, Gieles M, Gilkis A, González-Torà G, Gräfener G, Götberg YLL, Hawcroft C, Hénault-Brunet V, Herrero A, Holgado G, Janssens S, Johnston C, Josiek J, Justham S, Kalari VM, Katabi ZZ, Keszthelyi Z, Klencki J, Kubát J, Kubátová B, Langer N, Lefever RR, Ludwig B, Mackey J, Mahy L, Maíz Apellániz J, Mandel I, Maravelias G, Marchant P, Menon A, Najarro F, Oskinova LM, O’Grady AJG, Ovadia R, Patrick LR, Pauli D, Pawlak M, Ramachandran V, Renzo M, Rocha DF, Sander AAC, Sayada T, Schneider FRN, Schootemeijer A, Schösser EC, Schürmann C, Sen K, Shahaf S, Simón-Díaz S, Stoop M, Toonen S, Tramper F, Van Loon JT, Valli R, Van Son LAC, Vigna-Gómez A, Villaseñor JI, Vink JS, Wang C, Willcox R. 2024. Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC. Astronomy and Astrophysics. 690, A289.' mla: 'Shenar, T., et al. “Binarity at LOw Metallicity (BLOeM): A Spectroscopic VLT Monitoring Survey of Massive Stars in the SMC.” Astronomy and Astrophysics, vol. 690, A289, EDP Sciences, 2024, doi:10.1051/0004-6361/202451586.' short: T. Shenar, J. Bodensteiner, H. Sana, P.A. Crowther, D.J. Lennon, M. Abdul-Masih, L.A. Almeida, F. Backs, S.R. Berlanas, M. Bernini-Peron, J.M. Bestenlehner, D.M. Bowman, V.A. Bronner, N. Britavskiy, A. De Koter, S.E. De Mink, K. Deshmukh, C.J. Evans, M. Fabry, M. Gieles, A. Gilkis, G. González-Torà, G. Gräfener, Y.L.L. Götberg, C. Hawcroft, V. Hénault-Brunet, A. Herrero, G. Holgado, S. Janssens, C. Johnston, J. Josiek, S. Justham, V.M. Kalari, Z.Z. Katabi, Z. Keszthelyi, J. Klencki, J. Kubát, B. Kubátová, N. Langer, R.R. Lefever, B. Ludwig, J. Mackey, L. Mahy, J. Maíz Apellániz, I. Mandel, G. Maravelias, P. Marchant, A. Menon, F. Najarro, L.M. Oskinova, A.J.G. O’Grady, R. Ovadia, L.R. Patrick, D. Pauli, M. Pawlak, V. Ramachandran, M. Renzo, D.F. Rocha, A.A.C. Sander, T. Sayada, F.R.N. Schneider, A. Schootemeijer, E.C. Schösser, C. Schürmann, K. Sen, S. Shahaf, S. Simón-Díaz, M. Stoop, S. Toonen, F. Tramper, J.T. Van Loon, R. Valli, L.A.C. Van Son, A. Vigna-Gómez, J.I. Villaseñor, J.S. Vink, C. Wang, R. Willcox, Astronomy and Astrophysics 690 (2024). date_created: 2024-11-03T23:01:44Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:31:11Z day: '01' ddc: - '520' department: - _id: YlGo doi: 10.1051/0004-6361/202451586 external_id: arxiv: - '2407.14593' isi: - '001336770600014' file: - access_level: open_access checksum: b378b36726591f3479a927d924ab8e77 content_type: application/pdf creator: dernst date_created: 2024-11-04T09:52:26Z date_updated: 2024-11-04T09:52:26Z file_id: '18500' file_name: 2024_AstronomyAstrophysics_Shenar.pdf file_size: 4267349 relation: main_file success: 1 file_date_updated: 2024-11-04T09:52:26Z has_accepted_license: '1' intvolume: ' 690' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version publication: Astronomy and Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: 'Binarity at LOw Metallicity (BLOeM): A spectroscopic VLT monitoring survey of massive stars in the SMC' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 690 year: '2024' ... --- OA_place: publisher OA_type: diamond _id: '18493' abstract: - lang: eng text: "Context. The escape of Lyman-α photons at redshifts greater than two is an ongoing subject of study and an important quantity to further understanding of Lyman-α emitters (LAEs), the transmission of Lyman-α photons through the interstellar medium and intergalactic medium, and the impact these LAEs have on cosmic reionisation.\r\n\r\nAims. This study aims to assess the Lyman-α escape fraction, fesc, Lyα, over the redshift range 2.9 < z < 6.7, focusing on Very Large Telescope/Multi Unit Spectroscopic Explorer (VLT/MUSE) selected, gravitationally lensed, intrinsically faint LAEs. These galaxies are of particular interest as the potential drivers of cosmic reionisation.\r\n\r\nMethods. We assessed fesc, Lyα in two ways: through an individual study of 96 LAEs behind the A2744 lensing cluster, with James Webb Space Telescope/Near-Infrared Camera (JWST/NIRCam) and HST data, and through a study of the global evolution of fesc, Lyα using the state-of-the-art luminosity functions for LAEs and the UV-selected ‘parent’ population (dust-corrected). We compared these studies to those in the literature based on brighter samples.\r\n\r\nResults. We find a negligible redshift evolution of fesc, Lyα for our individual galaxies; it is likely that it was washed out by significant intrinsic scatter. We observed a more significant evolution towards higher escape fractions with decreasing UV magnitude and fit this relation. When comparing the two luminosity functions to derive fesc, Lyα in a global sense, we saw agreement with previous literature when integrating the luminosity functions to a bright limit. However, when integrating using a faint limit equivalent to the observational limits of our samples, we observed enhanced values of fesc, Lyα, particularly around z ∼ 6, where fesc, Lyα becomes consistent with 100% escape. This indicates for the faint regimes we sampled that galaxies towards reionisation tend to allow very large fractions of Lyman-α photons to escape. We interpret this as evidence of a lack of any significant dust in these populations; our sample is likely dominated by young, highly star-forming chemically unevolved galaxies. Finally, we assessed the contribution of the LAE population to reionisation using our latest values for fesc, Lyα and the LAE luminosity density. The dependence on the escape fraction of Lyman continuum photons is strong, but for values similar to those observed recently in z ∼ 3 LAEs and high-redshift analogues, LAEs could provide all the ionising emissivity necessary for reionisation." acknowledgement: "This work is done based on observations made with ESO Telescopes at the La Silla Paranal Observatory under programme IDs 060.A-9345, 092.A-0472, 094.A-0115, 095.A-0181, 096.A-0710, 097.A0269, 100.A-0249, and 294.A-5032. Also based on observations obtained with the\r\nNASA/ESA Hubble Space Telescope, retrieved from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI). STScI is operated by the Association of Universities for Research in Astronomy, Inc. under NASA contract NAS 5-26555. All plots in this paper were created using Matplotlib (Hunter 2007). Part of this work was supported by the French CNRS, the Aix-Marseille University, the French Programme National de Cosmologie et Galaxies (PNCG) of CNRS/INSU with INP and IN2P3, co-funded by CEA and CNES. This work also received support from the French government under the France 2030 investment plan, as part of the Excellence Initiative of Aix-Marseille University - A*MIDEX (AMX-19-IET-008 - IPhU).\r\nFinancial support from the World Laboratory, the Odon Vallet Foundation and VNSC is gratefully acknowledged. Tran Thi Thai was funded by Vingroup JSC and supported by the Master, PhD Scholarship Programme of Vingroup Innovation Foundation (VINIF), Institute of Big Data, code VINIF.2023.TS.108. This research was funded by Vingroup Innovation Foundation under project code VINIF.2023.DA.057." article_number: A302 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: I. full_name: Goovaerts, I. last_name: Goovaerts - first_name: T. T. full_name: Thai, T. T. last_name: Thai - first_name: R. full_name: Pello, R. last_name: Pello - first_name: P. full_name: Tuan-Anh, P. last_name: Tuan-Anh - first_name: N. full_name: Laporte, N. last_name: Laporte - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: T. full_name: Nanayakkara, T. last_name: Nanayakkara - first_name: J. full_name: Pharo, J. last_name: Pharo citation: ama: Goovaerts I, Thai TT, Pello R, et al. Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution. Astronomy and Astrophysics. 2024;690. doi:10.1051/0004-6361/202451432 apa: Goovaerts, I., Thai, T. T., Pello, R., Tuan-Anh, P., Laporte, N., Matthee, J. J., … Pharo, J. (2024). Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202451432 chicago: Goovaerts, I., T. T. Thai, R. Pello, P. Tuan-Anh, N. Laporte, Jorryt J Matthee, T. Nanayakkara, and J. Pharo. “Charting the Lyman-α Escape Fraction in the Range 2.9 < z < 6.7 and Consequences for the LAE Reionisation Contribution.” Astronomy and Astrophysics. EDP Sciences, 2024. https://doi.org/10.1051/0004-6361/202451432. ieee: I. Goovaerts et al., “Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution,” Astronomy and Astrophysics, vol. 690. EDP Sciences, 2024. ista: Goovaerts I, Thai TT, Pello R, Tuan-Anh P, Laporte N, Matthee JJ, Nanayakkara T, Pharo J. 2024. Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution. Astronomy and Astrophysics. 690, A302. mla: Goovaerts, I., et al. “Charting the Lyman-α Escape Fraction in the Range 2.9 < z < 6.7 and Consequences for the LAE Reionisation Contribution.” Astronomy and Astrophysics, vol. 690, A302, EDP Sciences, 2024, doi:10.1051/0004-6361/202451432. short: I. Goovaerts, T.T. Thai, R. Pello, P. Tuan-Anh, N. Laporte, J.J. Matthee, T. Nanayakkara, J. Pharo, Astronomy and Astrophysics 690 (2024). date_created: 2024-11-03T23:01:45Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:28:28Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1051/0004-6361/202451432 external_id: arxiv: - '2408.00517' isi: - '001339205700015' file: - access_level: open_access checksum: 4007e2b0fadf93bea61c5bec3fc97e87 content_type: application/pdf creator: dernst date_created: 2024-11-04T08:04:44Z date_updated: 2024-11-04T08:04:44Z file_id: '18495' file_name: 2024_AstronomyAstrophysics_Goovaerts.pdf file_size: 2008461 relation: main_file success: 1 file_date_updated: 2024-11-04T08:04:44Z has_accepted_license: '1' intvolume: ' 690' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version publication: Astronomy and Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: Charting the Lyman-α escape fraction in the range 2.9 < z < 6.7 and consequences for the LAE reionisation contribution tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 690 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18494' abstract: - lang: eng text: We expect luminous (M 1450 ≲ −26.5) high-redshift quasars to trace the highest-density peaks in the early Universe. Here, we present observations of four z ≳ 6 quasar fields using JWST/NIRCam in the imaging and wide-field slitless spectroscopy mode and report a wide range in the number of detected [O iii]-emitting galaxies in the quasars’ environments, ranging between a density enhancement of δ ≈ 65 within a 2 cMpc radius—one of the largest protoclusters during the Epoch of Reionization discovered to date—to a density contrast consistent with zero, indicating the presence of a UV-luminous quasar in a region comparable to the average density of the Universe. By measuring the two-point cross-correlation function of quasars and their surrounding galaxies, as well as the galaxy autocorrelation function, we infer a correlation length of quasars at 〈z〉 = 6.25 of r 0 QQ = 22.0 − 2.9 + 3.0 cMpc h − 1 , while we obtain a correlation length of the [O iii]-emitting galaxies of r 0 GG = 4.1 ± 0.3 cMpc h − 1 . By comparing the correlation functions to dark-matter-only simulations we estimate the minimum mass of the quasars’ host dark matter halos to be log 10 ( M halo , min / M ⊙ ) = 12.43 − 0.15 + 0.13 (and log 10 ( M halo , min [ OIII ] / M ⊙ ) = 10.56 − 0.03 + 0.05 for the [O iii] emitters), indicating that (a) luminous quasars do not necessarily reside within the most overdense regions in the early Universe, and that (b) the UV-luminous duty cycle of quasar activity at these redshifts is f duty ≪ 1. Such short quasar activity timescales challenge our understanding of early supermassive black hole growth and provide evidence for highly dust-obscured growth phases or episodic, radiatively inefficient accretion rates. acknowledgement: "The authors would like to thank the anonymous referee for the thoughtful comments, which significantly improved our manuscript, and Jan-Torge Schindler, Jiamu Huang, and Feige Wang for helpful discussions.\r\n\r\nJ.F.H. and E.P. acknowledge support from the European Research Council (ERC) under the European Unions Horizon 2020 research and innovation program (grant agreement No. 885301). J.M. acknowledges support from the European Union (ERC, AGENTS, 101076224).\r\n\r\nThis work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The JWST data presented in this article were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. The specific observations analyzed are associated with program #1243 and can be accessed via doi:10.17909/m5mp-5v90.\r\n\r\nThis work used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through a Directors Discretionary Time allocation in 2023/24, under the auspices of the UKRI-funded DiRAC Federation Project. The equipment was funded by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure.\r\n\r\nWe thank the Instituto de Astrofisica de Andalucia (IAA-CSIC), Centro de Supercomputacion de Galicia (CESGA), and Spanish Academic and Research Network (RedIRIS) in Spain for hosting Uchuu DR1, DR2, and DR3 in the Skies & Universes site for cosmological simulations. The Uchuu simulations were carried out on the Aterui II supercomputer at the Center for Computational Astrophysics, CfCA, of the National Astronomical Observatory of Japan, and the K computer at the RIKEN Advanced Institute for Computational Science. The Uchuu Data Releases efforts have made use of the skunIAA_RedIRIS and skun6IAA computer facilities managed by the IAA-CSIC in Spain (MICINN EU-Feder grant EQC2018-004366-P)." article_number: '275' article_processing_charge: Yes article_type: original author: - first_name: Anna Christina full_name: Eilers, Anna Christina last_name: Eilers - first_name: Ruari full_name: Mackenzie, Ruari last_name: Mackenzie - first_name: Elia full_name: Pizzati, Elia last_name: Pizzati - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Joseph F. full_name: Hennawi, Joseph F. last_name: Hennawi - first_name: Haowen full_name: Zhang, Haowen last_name: Zhang - first_name: Rongmon full_name: Bordoloi, Rongmon last_name: Bordoloi - first_name: Daichi full_name: Kashino, Daichi last_name: Kashino - first_name: Simon J. full_name: Lilly, Simon J. last_name: Lilly - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Robert A. full_name: Simcoe, Robert A. last_name: Simcoe - first_name: Minghao full_name: Yue, Minghao last_name: Yue - first_name: Carlos S. full_name: Frenk, Carlos S. last_name: Frenk - first_name: John C. full_name: Helly, John C. last_name: Helly - first_name: Matthieu full_name: Schaller, Matthieu last_name: Schaller - first_name: Joop full_name: Schaye, Joop last_name: Schaye citation: ama: Eilers AC, Mackenzie R, Pizzati E, et al. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 2024;974(2). doi:10.3847/1538-4357/ad778b apa: Eilers, A. C., Mackenzie, R., Pizzati, E., Matthee, J. J., Hennawi, J. F., Zhang, H., … Schaye, J. (2024). EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ad778b chicago: Eilers, Anna Christina, Ruari Mackenzie, Elia Pizzati, Jorryt J Matthee, Joseph F. Hennawi, Haowen Zhang, Rongmon Bordoloi, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778b. ieee: A. C. Eilers et al., “EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6,” Astrophysical Journal, vol. 974, no. 2. IOP Publishing, 2024. ista: Eilers AC, Mackenzie R, Pizzati E, Matthee JJ, Hennawi JF, Zhang H, Bordoloi R, Kashino D, Lilly SJ, Naidu RP, Simcoe RA, Yue M, Frenk CS, Helly JC, Schaller M, Schaye J. 2024. EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6. Astrophysical Journal. 974(2), 275. mla: Eilers, Anna Christina, et al. “EIGER. VI. The Correlation Function, Host Halo Mass, and Duty Cycle of Luminous Quasars at z ≳ 6.” Astrophysical Journal, vol. 974, no. 2, 275, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778b. short: A.C. Eilers, R. Mackenzie, E. Pizzati, J.J. Matthee, J.F. Hennawi, H. Zhang, R. Bordoloi, D. Kashino, S.J. Lilly, R.P. Naidu, R.A. Simcoe, M. Yue, C.S. Frenk, J.C. Helly, M. Schaller, J. Schaye, Astrophysical Journal 974 (2024). date_created: 2024-11-03T23:01:45Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:29:05Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.3847/1538-4357/ad778b external_id: isi: - '001338877100001' file: - access_level: open_access checksum: 1fcac3d11d01d91cf2bb4963b6e10b22 content_type: application/pdf creator: dernst date_created: 2024-11-04T08:42:23Z date_updated: 2024-11-04T08:42:23Z file_id: '18496' file_name: 2024_AstrophysicalJour_Eilers.pdf file_size: 1042470 relation: main_file success: 1 file_date_updated: 2024-11-04T08:42:23Z has_accepted_license: '1' intvolume: ' 974' isi: 1 issue: '2' language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: bd9b2118-d553-11ed-ba76-db24564edfea grant_number: '101076224' name: Young galaxies as tracers and agents of cosmic reionization publication: Astrophysical Journal publication_identifier: eissn: - 1538-4357 issn: - 0004-637X publication_status: published publisher: IOP Publishing quality_controlled: '1' scopus_import: '1' status: public title: EIGER. VI. The correlation function, host halo mass, and duty cycle of luminous quasars at z ≳ 6 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 974 year: '2024' ... --- OA_place: repository _id: '18498' abstract: - lang: eng text: 'Scripts and data used in the research study Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. https://doi.org/10.1101/2023.09.27.559715' article_processing_charge: No author: - first_name: Diego Fernando full_name: Garcia Castillo, Diego Fernando id: ae681a14-dc74-11ea-a0a7-c6ef18161701 last_name: Garcia Castillo - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Rui full_name: Faria, Rui last_name: Faria - first_name: Jenny full_name: Larsson, Jenny last_name: Larsson - first_name: Sean full_name: Stankowski, Sean id: 43161670-5719-11EA-8025-FABC3DDC885E last_name: Stankowski - first_name: Roger full_name: Butlin, Roger last_name: Butlin - first_name: Kerstin full_name: Johannesson, Kerstin last_name: Johannesson - first_name: Anja M full_name: Westram, Anja M id: 3C147470-F248-11E8-B48F-1D18A9856A87 last_name: Westram orcid: 0000-0003-1050-4969 citation: ama: 'Garcia Castillo DF, Barton NH, Faria R, et al. Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. 2024. doi:10.5281/ZENODO.12159343' apa: 'Garcia Castillo, D. F., Barton, N. H., Faria, R., Larsson, J., Stankowski, S., Butlin, R., … Westram, A. M. (2024). Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails. Zenodo. https://doi.org/10.5281/ZENODO.12159343' chicago: 'Garcia Castillo, Diego Fernando, Nicholas H Barton, Rui Faria, Jenny Larsson, Sean Stankowski, Roger Butlin, Kerstin Johannesson, and Anja M Westram. “Data and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails.” Zenodo, 2024. https://doi.org/10.5281/ZENODO.12159343.' ieee: 'D. F. Garcia Castillo et al., “Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails.” Zenodo, 2024.' ista: 'Garcia Castillo DF, Barton NH, Faria R, Larsson J, Stankowski S, Butlin R, Johannesson K, Westram AM. 2024. Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails, Zenodo, 10.5281/ZENODO.12159343.' mla: 'Garcia Castillo, Diego Fernando, et al. Data and Code for: Predicting Rapid Adaptation in Time from Adaptation in Space: A 30-Year Field Experiment in Marine Snails. Zenodo, 2024, doi:10.5281/ZENODO.12159343.' short: D.F. Garcia Castillo, N.H. Barton, R. Faria, J. Larsson, S. Stankowski, R. Butlin, K. Johannesson, A.M. Westram, (2024). corr_author: '1' date_created: 2024-11-04T09:33:17Z date_published: 2024-06-19T00:00:00Z date_updated: 2026-04-16T12:20:37Z day: '19' ddc: - '570' department: - _id: NiBa doi: 10.5281/ZENODO.12159343 has_accepted_license: '1' main_file_link: - open_access: '1' url: https://doi.org/10.5281/zenodo.12159344 month: '06' oa: 1 oa_version: Published Version publisher: Zenodo related_material: record: - id: '20991' relation: used_in_publication status: public - id: '18491' relation: used_in_publication status: public status: public title: 'Data and code for: Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: research_data_reference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- OA_place: repository OA_type: free access _id: '18503' abstract: - lang: eng text: "In 1996, Karger [Kar96] gave a startling randomized algorithm that finds a minimum-cut in a (weighted) graph in time O(m log3 n) which he termed near-linear time meaning linear (in the size of the input) times a polylogarthmic factor. In this paper, we give the first deterministic algorithm which runs in near-linear time for weighted graphs.\r\nPreviously, the breakthrough results of Kawarabayashi and Thorup [KT19] gave a near-linear time algorithm for simple graphs (which was improved to have running time O(m log2 n log log n) in [HRW20].) The main technique here is a clustering procedure that perfectly preserves minimum cuts. Recently, Li [Li21] gave an m1+o(1) deterministic minimum-cut algorithm for weighted graphs; this form of running time has been termed “almost-linear”. Li uses almost-linear time deterministic expander decompositions which do not perfectly preserve minimum cuts, but he can use these clusterings to, in a sense, “derandomize” the methods of Karger.\r\nIn terms of techniques, we provide a structural theorem that says there exists a sparse clustering that preserves minimum cuts in a weighted graph with o(1) error. In addition, we construct it deterministically in near linear time. This was done exactly for simple graphs in [KT19, HRW20] and with polylogarithmic error for weighted graphs in [Li21]. Extending the techniques in [KT19, HRW20] to weighted graphs presents significant challenges, and moreover, the algorithm can only polylogarithmically approximately preserve minimum cuts. A remaining challenge is to reduce the polylogarithmic-approximate clusterings to 1 + o(1/ log n)-approximate so that they can be applied recursively as in [Li21] over O(log n) many levels. This is an additional challenge that requires building on properties of tree-packings in the presence of a wide range of edge weights to, for example, find sources for local flow computations which identify minimum cuts that cross clusters." acknowledgement: This project has received funding from the European Research Council(ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101019564 “The Design of Modern Fully Dynamic Data Structures (MoDyn-Struct)” and the Austrian Science Fund (FWF) project Z 422-N, project “Static and Dynamic Hierarchical Graph Decompositions”, I 5982-N, and project “Fast Algorithms for a Reactive Network Layer (ReactNet)”, P33775-N, with additional funding from the netidee SCIENCE Stiftung, 2020–2024. article_processing_charge: No arxiv: 1 author: - first_name: Monika H full_name: Henzinger, Monika H id: 540c9bbd-f2de-11ec-812d-d04a5be85630 last_name: Henzinger orcid: 0000-0002-5008-6530 - first_name: Jason full_name: Li, Jason last_name: Li - first_name: Satish full_name: Rao, Satish last_name: Rao - first_name: Di full_name: Wang, Di last_name: Wang citation: ama: 'Henzinger M, Li J, Rao S, Wang D. Deterministic near-linear time minimum cut in weighted graphs. In: 35th Annual ACM-SIAM Symposium on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2024:3089-3139. doi:10.1137/1.9781611977912.111' apa: 'Henzinger, M., Li, J., Rao, S., & Wang, D. (2024). Deterministic near-linear time minimum cut in weighted graphs. In 35th Annual ACM-SIAM Symposium on Discrete Algorithms (pp. 3089–3139). Alexandria, VA,  United States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611977912.111' chicago: Henzinger, Monika, Jason Li, Satish Rao, and Di Wang. “Deterministic Near-Linear Time Minimum Cut in Weighted Graphs.” In 35th Annual ACM-SIAM Symposium on Discrete Algorithms, 3089–3139. Society for Industrial and Applied Mathematics, 2024. https://doi.org/10.1137/1.9781611977912.111. ieee: M. Henzinger, J. Li, S. Rao, and D. Wang, “Deterministic near-linear time minimum cut in weighted graphs,” in 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Alexandria, VA,  United States, 2024, pp. 3089–3139. ista: 'Henzinger M, Li J, Rao S, Wang D. 2024. Deterministic near-linear time minimum cut in weighted graphs. 35th Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 3089–3139.' mla: Henzinger, Monika, et al. “Deterministic Near-Linear Time Minimum Cut in Weighted Graphs.” 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024, pp. 3089–139, doi:10.1137/1.9781611977912.111. short: M. Henzinger, J. Li, S. Rao, D. Wang, in:, 35th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2024, pp. 3089–3139. conference: end_date: 2024-01-10 location: Alexandria, VA, United States name: 'SODA: Symposium on Discrete Algorithms' start_date: 2024-01-07 corr_author: '1' date_created: 2024-11-04T10:54:21Z date_published: 2024-01-04T00:00:00Z date_updated: 2025-06-24T12:09:26Z day: '04' department: - _id: MoHe doi: 10.1137/1.9781611977912.111 ec_funded: 1 external_id: arxiv: - '2401.05627' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2401.05627 month: '01' oa: 1 oa_version: Preprint page: 3089-3139 project: - _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62 call_identifier: H2020 grant_number: '101019564' name: The design and evaluation of modern fully dynamic data structures - _id: 34def286-11ca-11ed-8bc3-da5948e1613c grant_number: Z00422 name: Efficient algorithms - _id: bda196b2-d553-11ed-ba76-8e8ee6c21103 grant_number: I05982 name: Static and Dynamic Hierarchical Graph Decompositions - _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe grant_number: P33775 name: Fast Algorithms for a Reactive Network Layer publication: 35th Annual ACM-SIAM Symposium on Discrete Algorithms publication_identifier: eisbn: - '9781611977912' publication_status: published publisher: Society for Industrial and Applied Mathematics quality_controlled: '1' scopus_import: '1' status: public title: Deterministic near-linear time minimum cut in weighted graphs type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- OA_place: publisher OA_type: gold _id: '18515' abstract: - lang: eng text: "Understanding the role of evolutionary processes in shaping genetic variation has been a\r\nprimary goal in evolutionary genetics. In this regard, a key question is how genetically\r\ndistinct populations evolve in the face of gene flow, thereby generating genetic and\r\nphenotypic divergence and reproductive isolation (RI). This requires quantifying the role\r\nand relative contributions of prezygotic and postzygotic isolating mechanisms on the\r\nreduction of gene exchange between populations, and identifying regions in the genome\r\nthat mediate RI, which is often polygenic. Further, this needs distinguishing neutral and\r\nselected regions in the genome, and discerning how selection influences patterns of neutral\r\ndivergence.\r\nPopulation structure, defined as any deviation from panmixia, such as geographic distribution, movement and mating patterns of individuals, influences how genetic variation is\r\nstructured in space and shapes the neutral null model. Availability of large scale spatial\r\ngenomic datasets now enables us to detect signatures of population structure in genetic\r\ndata and infer population genetic parameters. Such inferences are crucial and have wide\r\napplications in biodiversity, conservation genetics, population management and medical\r\ngenetics. However, inferences are based on assumptions that do not always match the\r\ncomplex reality, thus leading to erroneous conclusions. Moreover, the role and interaction\r\nof heterogeneous population density and dispersal, which are ubiquitous in nature, has\r\nbeen challenging to study owing to their mathematical complexity. In such scenarios,\r\nfeedback between theory, data and simulations can prove to be useful.\r\nIn this thesis, I examine the effect of population structure on neutral genetic variation\r\nand barriers to gene exchange in hybridising populations, thereby bridging together the\r\nfields of spatial population genetics and speciation.\r\nDespite being a key concept in speciation, reproductive isolation (RI) lacks a quantitative\r\ndefinition and has been used and measured differently across different fields. Chapter 2\r\ngives a quantitative definition of RI, in terms of the effect of genetic differences on gene\r\nflow. We give analytical predictions for RI in a range of scenarios, in terms of effective migration rates for discrete populations and barrier strength for continuous populations.\r\nIn addition to this, we discuss current measures of RI and their limitations, and propose\r\nthe need for new measures that combine organismal and genetic perspectives of RI.\r\nIn chapter 3, I examine the combined effect of assortative mating, sexual selection\r\nand viability selection on RI. For this, we consider a polygenic ‘magic’ trait under a\r\nmainland-island model. We obtain novel theoretical predictions for molecular divergence\r\nin terms of effective migration rates, which bears a simple relationship to measurable\r\nfitness components of migrants and various early generation hybrids. We explore the\r\nconditions under which local adaptation can be maintained despite maladaptive gene flow\r\nand quantify the relative contributions of viability and sexual selection to genome-wide\r\nbarriers to gene flow.\r\nThe next two chapters of the thesis focus on a hybrid zone of Antirrhinum majus that\r\nconsist of two subspecies- the magenta flowered A. m. pseudomajus and the yellow\r\nflowered A.m. striatum. Previous studies have suggested that flower colour is target of\r\npollinator mediated selection and is influenced only by few genes. While these regions\r\nshow high genetic differentiation between the subspecies, the rest of the genome is seen\r\nto be well mixed. Chapter 4 examines the effects of heterogeneous population density\r\nand leptokurtic dispersal on isolation by distance and the distribution of heterozygosity\r\nby focusing on non-flower colour markers.\r\nChapter 5 analyses cline shapes and associations among 6 focal flower colour markers to\r\nunderstand how selection and dispersal maintain this hybrid zone. We see sharp coincident\r\nstepped clines at all loci and positive associations throughout the hybrid zone, contrary to\r\nthe expected patterns from diffusive gene flow. With a novel scheme of inferring dispersal\r\ncombined with multilocus simulations, we show that stepped clines do not reflect genetic\r\nbarriers to gene flow, but are rather a result of long-distance migration. This framework\r\nallows us to get realistic estimates gene flow and selection and shows how traditional cline\r\nanalysis may lead to inaccurate conclusions when assumptions of the theory are not met.\r\nOverall, this thesis investigates how different features of population structure leave\r\ndetectable signatures in genetic variation, namely in patterns of isolation by distance,\r\nlinkage disequilibrium and genetic divergence. It also highlights how effective migration\r\nrates provide useful way of analysing polygenic architectures and shed new light into\r\nhybrid zones. In doing so, I identify scenarios when simple models become insufficient\r\nand suggest possibe directions by combining genetic data with simulations." acknowledged_ssus: - _id: ScienComp acknowledgement: "I also acknowledge the funding agencies Marie Curie COFUND Doctoral Fellowship,\r\nAustrian Science Fund FWF (grant P32166) and ERC (grant PR1000ERC02) for financially\r\nsupporting my research over the years." alternative_title: - ISTA Thesis article_processing_charge: No author: - first_name: Parvathy full_name: Surendranadh, Parvathy id: 455235B8-F248-11E8-B48F-1D18A9856A87 last_name: Surendranadh orcid: 0000-0001-6395-386X citation: ama: Surendranadh P. Effect of population structure on neutral genetic variation and barriers to gene exchange. 2024. doi:10.15479/at:ista:18515 apa: Surendranadh, P. (2024). Effect of population structure on neutral genetic variation and barriers to gene exchange. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:18515 chicago: Surendranadh, Parvathy. “Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange.” Institute of Science and Technology Austria, 2024. https://doi.org/10.15479/at:ista:18515. ieee: P. Surendranadh, “Effect of population structure on neutral genetic variation and barriers to gene exchange,” Institute of Science and Technology Austria, 2024. ista: Surendranadh P. 2024. Effect of population structure on neutral genetic variation and barriers to gene exchange. Institute of Science and Technology Austria. mla: Surendranadh, Parvathy. Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange. Institute of Science and Technology Austria, 2024, doi:10.15479/at:ista:18515. short: P. Surendranadh, Effect of Population Structure on Neutral Genetic Variation and Barriers to Gene Exchange, Institute of Science and Technology Austria, 2024. corr_author: '1' date_created: 2024-11-06T21:25:37Z date_published: 2024-11-07T00:00:00Z date_updated: 2026-04-07T12:56:52Z day: '07' ddc: - '576' degree_awarded: PhD department: - _id: GradSch - _id: NiBa doi: 10.15479/at:ista:18515 file: - access_level: open_access checksum: c32cf7bc75748d9c551d8eb70178bbec content_type: application/pdf creator: psurendr date_created: 2024-11-07T10:59:29Z date_updated: 2024-11-07T10:59:29Z file_id: '18519' file_name: PhD_Thesis__Parvathy_071124_PDFA.pdf file_size: 37019760 relation: main_file success: 1 - access_level: closed checksum: 4417e02d54084d89e75734e18caaa96d content_type: application/zip creator: psurendr date_created: 2024-11-07T10:59:42Z date_updated: 2024-11-07T10:59:42Z file_id: '18520' file_name: PhD Thesis- Parvathy_071124.zip file_size: 41198857 relation: source_file file_date_updated: 2024-11-07T10:59:42Z has_accepted_license: '1' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-sa/4.0/ month: '11' oa: 1 oa_version: Published Version page: '219' project: - _id: 05959E1C-7A3F-11EA-A408-12923DDC885E grant_number: P32166 name: Snapdragon Speciation - _id: bd6958e0-d553-11ed-ba76-86eba6a76c00 grant_number: '101055327' name: Understanding the evolution of continuous genomes publication_identifier: issn: - 2663-337X publication_status: published publisher: Institute of Science and Technology Austria status: public supervisor: - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 title: Effect of population structure on neutral genetic variation and barriers to gene exchange tmp: image: /images/cc_by_nc_sa.png legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) short: CC BY-NC-SA (4.0) type: dissertation user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd year: '2024' ... --- APC_amount: 2748 EUR OA_place: publisher OA_type: hybrid _id: '18521' abstract: - lang: eng text: In distributed systems with processes that do not share a global clock, partial synchrony is achieved by clock synchronization that guarantees bounded clock skew among all applications. Existing solutions for distributed runtime verification under partial synchrony against temporal logic specifications are exact but suffer from significant computational overhead. In this paper, we propose an approximate distributed monitoring algorithm for Signal Temporal Logic (STL) that mitigates this issue by abstracting away potential interleaving behaviors. This conservative abstraction enables a significant speedup of the distributed monitors, albeit with a tradeoff in accuracy. We address this tradeoff with a methodology that combines our approximate monitor with its exact counterpart, resulting in enhanced efficiency without sacrificing precision. We evaluate our approach with multiple experiments, showcasing its efficacy in both real-world applications and synthetic examples. acknowledgement: This work was supported in part by the ERC-2020-AdG 101020093. This work is sponsored in part by the United States NSF CCF-2118356 award. This research was partially funded by A-IQ Ready (Chips JU, grant agreement No. 101096658). alternative_title: - LNCS article_processing_charge: Yes (in subscription journal) arxiv: 1 author: - first_name: Borzoo full_name: Bonakdarpour, Borzoo last_name: Bonakdarpour - first_name: Anik full_name: Momtaz, Anik last_name: Momtaz - first_name: Dejan full_name: Nickovic, Dejan id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87 last_name: Nickovic - first_name: Naci E full_name: Sarac, Naci E id: 8C6B42F8-C8E6-11E9-A03A-F2DCE5697425 last_name: Sarac citation: ama: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. In: 24th International Conference on Runtime Verification. Vol 15191. Springer Nature; 2024:282-301. doi:10.1007/978-3-031-74234-7_18' apa: 'Bonakdarpour, B., Momtaz, A., Nickovic, D., & Sarac, N. E. (2024). Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. In 24th International Conference on Runtime Verification (Vol. 15191, pp. 282–301). Istanbul, Turkey: Springer Nature. https://doi.org/10.1007/978-3-031-74234-7_18' chicago: 'Bonakdarpour, Borzoo, Anik Momtaz, Dejan Nickovic, and Naci E Sarac. “Approximate Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.” In 24th International Conference on Runtime Verification, 15191:282–301. Springer Nature, 2024. https://doi.org/10.1007/978-3-031-74234-7_18.' ieee: 'B. Bonakdarpour, A. Momtaz, D. Nickovic, and N. E. Sarac, “Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy,” in 24th International Conference on Runtime Verification, Istanbul, Turkey, 2024, vol. 15191, pp. 282–301.' ista: 'Bonakdarpour B, Momtaz A, Nickovic D, Sarac NE. 2024. Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy. 24th International Conference on Runtime Verification. RV: Conference on Runtime Verification, LNCS, vol. 15191, 282–301.' mla: 'Bonakdarpour, Borzoo, et al. “Approximate Distributed Monitoring under Partial Synchrony: Balancing Speed & Accuracy.” 24th International Conference on Runtime Verification, vol. 15191, Springer Nature, 2024, pp. 282–301, doi:10.1007/978-3-031-74234-7_18.' short: B. Bonakdarpour, A. Momtaz, D. Nickovic, N.E. Sarac, in:, 24th International Conference on Runtime Verification, Springer Nature, 2024, pp. 282–301. conference: end_date: 2024-10-17 location: Istanbul, Turkey name: 'RV: Conference on Runtime Verification' start_date: 2024-10-15 corr_author: '1' date_created: 2024-11-10T23:01:58Z date_published: 2024-10-12T00:00:00Z date_updated: 2026-05-20T08:43:20Z day: '12' ddc: - '000' department: - _id: ToHe - _id: GradSch doi: 10.1007/978-3-031-74234-7_18 ec_funded: 1 external_id: arxiv: - '2408.05033' isi: - '001420093700018' file: - access_level: open_access checksum: 7b8ca21b8c19ab796fa445b0e54003ca content_type: application/pdf creator: dernst date_created: 2024-11-11T09:42:28Z date_updated: 2024-11-11T09:42:28Z file_id: '18539' file_name: 2024_LNCS_Bonakdarpour.pdf file_size: 1897101 relation: main_file success: 1 file_date_updated: 2024-11-11T09:42:28Z has_accepted_license: '1' intvolume: ' 15191' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version page: 282-301 project: - _id: 62781420-2b32-11ec-9570-8d9b63373d4d call_identifier: H2020 grant_number: '101020093' name: Vigilant Algorithmic Monitoring of Software publication: 24th International Conference on Runtime Verification publication_identifier: eissn: - 1611-3349 isbn: - '9783031742330' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: 'Approximate distributed monitoring under partial synchrony: Balancing speed & accuracy' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15191 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18522' abstract: - lang: eng text: The Golgi apparatus is essential for protein sorting, yet its quality control mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic length of α-helical transmembrane domains (TMDs) at the Golgi. Thereby the Dsc complex likely interacts with orphaned ER and Golgi proteins that have shorter TMDs and ubiquitinates them for targeted degradation. Some Dsc substrates will be extracted by Cdc48 for endosome and Golgi associated proteasomal degradation (EGAD), while others will undergo ESCRT dependent vacuolar degradation. Some substrates are degraded by both, EGAD- or ESCRT pathways. The accumulation of Dsc substrates entails a specific increase in glycerophospholipids with shorter and asymmetric fatty acyl chains. Hence, the Dsc complex mediates the selective degradation of orphaned proteins at the sorting center of cells, which prevents their spreading across other organelles and thereby preserves cellular membrane protein and lipid composition. acknowledgement: 'We thank Snezhana Oliferenko, Hesso Farhan, Chris Dunworth, and Lukas A Huber for critically reading the manuscript, Ming Li, Peter Espenshade, Sebastien Leon, and Scott Emr for reagents, Bob Kaufmann for help in characterizing the Dsc2 L1 loop mutant. This research was funded in part by the Austrian Science Fund (FWF) (10.55776/P32161, 10.55776/P34907, 10.55776/DOC82 to DT, and 10.55776/P36187 to OS), by a Lipotype lipidomics excellence award (LEA 2019) to OS, by a Luxembourg National Research Fund (FNR): Grant #13571826 to YW, and by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 847681 (to KRL). For open access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission.' article_number: '9257' article_processing_charge: Yes article_type: original author: - first_name: Yannick full_name: Weyer, Yannick last_name: Weyer - first_name: Sinead I. full_name: Schwabl, Sinead I. last_name: Schwabl - first_name: Xuechen full_name: Tang, Xuechen last_name: Tang - first_name: Astha full_name: Purwar, Astha last_name: Purwar - first_name: Konstantin full_name: Siegmann, Konstantin last_name: Siegmann - first_name: Angela full_name: Ruepp, Angela last_name: Ruepp - first_name: Theresia full_name: Dunzendorfer-Matt, Theresia last_name: Dunzendorfer-Matt - first_name: Michael A. full_name: Widerin, Michael A. last_name: Widerin - first_name: Veronika full_name: Niedrist, Veronika last_name: Niedrist - first_name: Noa J.M. full_name: Mutsters, Noa J.M. last_name: Mutsters - first_name: Maria G. full_name: Tettamanti, Maria G. last_name: Tettamanti - first_name: Sabine full_name: Weys, Sabine id: caffa136-9669-11ed-9092-ceac12ac9c05 last_name: Weys - first_name: Bettina full_name: Sarg, Bettina last_name: Sarg - first_name: Leopold full_name: Kremser, Leopold last_name: Kremser - first_name: Klaus R. full_name: Liedl, Klaus R. last_name: Liedl - first_name: Oliver full_name: Schmidt, Oliver last_name: Schmidt - first_name: David full_name: Teis, David last_name: Teis citation: ama: Weyer Y, Schwabl SI, Tang X, et al. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications. 2024;15. doi:10.1038/s41467-024-53676-6 apa: Weyer, Y., Schwabl, S. I., Tang, X., Purwar, A., Siegmann, K., Ruepp, A., … Teis, D. (2024). The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-024-53676-6 chicago: Weyer, Yannick, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” Nature Communications. Springer Nature, 2024. https://doi.org/10.1038/s41467-024-53676-6. ieee: Y. Weyer et al., “The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi,” Nature Communications, vol. 15. Springer Nature, 2024. ista: Weyer Y, Schwabl SI, Tang X, Purwar A, Siegmann K, Ruepp A, Dunzendorfer-Matt T, Widerin MA, Niedrist V, Mutsters NJM, Tettamanti MG, Weys S, Sarg B, Kremser L, Liedl KR, Schmidt O, Teis D. 2024. The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi. Nature Communications. 15, 9257. mla: Weyer, Yannick, et al. “The Dsc Ubiquitin Ligase Complex Identifies Transmembrane Degrons to Degrade Orphaned Proteins at the Golgi.” Nature Communications, vol. 15, 9257, Springer Nature, 2024, doi:10.1038/s41467-024-53676-6. short: Y. Weyer, S.I. Schwabl, X. Tang, A. Purwar, K. Siegmann, A. Ruepp, T. Dunzendorfer-Matt, M.A. Widerin, V. Niedrist, N.J.M. Mutsters, M.G. Tettamanti, S. Weys, B. Sarg, L. Kremser, K.R. Liedl, O. Schmidt, D. Teis, Nature Communications 15 (2024). date_created: 2024-11-10T23:01:58Z date_published: 2024-12-01T00:00:00Z date_updated: 2026-03-05T11:20:12Z day: '01' ddc: - '570' doi: 10.1038/s41467-024-53676-6 external_id: isi: - '001345548100007' pmid: - '39461958' file: - access_level: open_access checksum: 32c986fc3babec999c03a5c043310f40 content_type: application/pdf creator: dernst date_created: 2025-01-22T14:36:33Z date_updated: 2025-01-22T14:36:33Z file_id: '18870' file_name: 2024_NatureComm_Weyer.pdf file_size: 5634494 relation: main_file success: 1 file_date_updated: 2025-01-22T14:36:33Z has_accepted_license: '1' intvolume: ' 15' isi: 1 language: - iso: eng month: '12' oa: 1 oa_version: Published Version pmid: 1 publication: Nature Communications publication_identifier: eissn: - 2041-1723 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 15 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18523' abstract: - lang: eng text: "Recent observations from the EIGER JWST program have measured for the first time the quasar–galaxy cross-correlation function at z ≈ 6. The autocorrelation function of faint z ≈ 6 quasars was also recently estimated. These measurements provide key insights into the properties of quasars and galaxies at high redshift and their relation with the host dark matter haloes. In this work, we interpret these data building upon an empirical quasar population model that has been applied successfully to quasar clustering and demographic measurements at z ≈ 2–4. We use a new, large-volume N-body simulation with more than a trillion particles, FLAMINGO-10k, to model quasars and galaxies simultaneously. We successfully reproduce observations of z ≈ 6 quasars and galaxies (i.e. their clustering properties and luminosity functions), and infer key quantities such as their luminosity–halo mass relation, the mass function of their host haloes, and their duty cycle/occupation fraction. Our key findings\r\nare (i) quasars reside on average in ≈ 1012.5 M haloes (corresponding to ≈ 5σ fluctuations in the initial conditions of the linear density field), but the distribution of host halo masses is quite broad; (ii) the duty cycle of (UV-bright) quasar activity is relatively low (≈ 1 per cent); (iii) galaxies (that are bright in [O III]) live in much smaller haloes (≈ 1010.9 M) and have a larger duty cycle (occupation fraction) of ≈ 13 per cent. Finally, we focus on the inferred properties of quasars and present a homogeneous analysis of their evolution with redshift. The picture that emerges reveals a strong evolution of the host halo mass and duty cycle of quasars at z ≈ 2–6, and calls for new investigations of the role of quasar activity across cosmic time." acknowledgement: "We are grateful to Junya Arita and the SHELLQs team for sharing their data on the quasar autocorrelation function and to Jan-Torge Schindler for discussion on the QLF. We acknowledge helpful conversations with the ENIGMA group at UC Santa Barbara and Leiden University. EP is grateful to Rob McGibbon and Victor Forouhar Moreno for help with the simulation outputs, and to Timo Kist, Jiamu Huang, and Vikram Khaire for comments on an early version of the manuscript. JFH and EP acknowledge support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement No 885301). This work is partly supported by funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 860744 (BiD4BESt). FW acknowledges support from NSF grant AST-2308258. This work used the DiRAC Memory Intensive service (Cosma8) at the University of Durham, which is part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). Access to DiRAC resources was granted through a Director’s Discretionary Time allocation in 2023/24, under the auspices of the UKRI-funded\r\nDiRAC Federation Project. The equipment was funded by BEIS capital funding via STFC capital grants ST/K00042X/1, ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University, and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure." article_processing_charge: Yes article_type: original author: - first_name: Elia full_name: Pizzati, Elia last_name: Pizzati - first_name: Joseph F. full_name: Hennawi, Joseph F. last_name: Hennawi - first_name: Joop full_name: Schaye, Joop last_name: Schaye - first_name: Matthieu full_name: Schaller, Matthieu last_name: Schaller - first_name: Anna Christina full_name: Eilers, Anna Christina last_name: Eilers - first_name: Feige full_name: Wang, Feige last_name: Wang - first_name: Carlos S. full_name: Frenk, Carlos S. last_name: Frenk - first_name: Willem full_name: Elbers, Willem last_name: Elbers - first_name: John C. full_name: Helly, John C. last_name: Helly - first_name: Ruari full_name: Mackenzie, Ruari last_name: Mackenzie - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Rongmon full_name: Bordoloi, Rongmon last_name: Bordoloi - first_name: Daichi full_name: Kashino, Daichi last_name: Kashino - first_name: Rohan P. full_name: Naidu, Rohan P. last_name: Naidu - first_name: Minghao full_name: Yue, Minghao last_name: Yue citation: ama: Pizzati E, Hennawi JF, Schaye J, et al. A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. 2024;534(4):3155-3175. doi:10.1093/mnras/stae2307 apa: Pizzati, E., Hennawi, J. F., Schaye, J., Schaller, M., Eilers, A. C., Wang, F., … Yue, M. (2024). A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/stae2307 chicago: Pizzati, Elia, Joseph F. Hennawi, Joop Schaye, Matthieu Schaller, Anna Christina Eilers, Feige Wang, Carlos S. Frenk, et al. “A Unified Model for the Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2024. https://doi.org/10.1093/mnras/stae2307. ieee: E. Pizzati et al., “A unified model for the clustering of quasars and galaxies at z ≈ 6,” Monthly Notices of the Royal Astronomical Society, vol. 534, no. 4. Oxford University Press, pp. 3155–3175, 2024. ista: Pizzati E, Hennawi JF, Schaye J, Schaller M, Eilers AC, Wang F, Frenk CS, Elbers W, Helly JC, Mackenzie R, Matthee JJ, Bordoloi R, Kashino D, Naidu RP, Yue M. 2024. A unified model for the clustering of quasars and galaxies at z ≈ 6. Monthly Notices of the Royal Astronomical Society. 534(4), 3155–3175. mla: Pizzati, Elia, et al. “A Unified Model for the Clustering of Quasars and Galaxies at z ≈ 6.” Monthly Notices of the Royal Astronomical Society, vol. 534, no. 4, Oxford University Press, 2024, pp. 3155–75, doi:10.1093/mnras/stae2307. short: E. Pizzati, J.F. Hennawi, J. Schaye, M. Schaller, A.C. Eilers, F. Wang, C.S. Frenk, W. Elbers, J.C. Helly, R. Mackenzie, J.J. Matthee, R. Bordoloi, D. Kashino, R.P. Naidu, M. Yue, Monthly Notices of the Royal Astronomical Society 534 (2024) 3155–3175. date_created: 2024-11-10T23:01:58Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:40:22Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1093/mnras/stae2307 external_id: isi: - '001335663900008' file: - access_level: open_access checksum: 9ea6285dd1d04d7a9e7b40a4c9e11edb content_type: application/pdf creator: dernst date_created: 2024-11-12T07:17:26Z date_updated: 2024-11-12T07:17:26Z file_id: '18542' file_name: 2024_MonthlyNRoyalAstronSoc_Pizzati.pdf file_size: 2954312 relation: main_file success: 1 file_date_updated: 2024-11-12T07:17:26Z has_accepted_license: '1' intvolume: ' 534' isi: 1 issue: '4' language: - iso: eng month: '11' oa: 1 oa_version: Published Version page: 3155-3175 publication: Monthly Notices of the Royal Astronomical Society publication_identifier: eissn: - 1365-2966 issn: - 0035-8711 publication_status: published publisher: Oxford University Press quality_controlled: '1' scopus_import: '1' status: public title: A unified model for the clustering of quasars and galaxies at z ≈ 6 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 534 year: '2024' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold _id: '18524' abstract: - lang: eng text: Recent works have constrained the binary fraction of evolved populations of massive stars in local galaxies such as red supergiants and Wolf–Rayet stars, but the binary fraction of yellow supergiants (YSGs) in the Hertzsprung gap remains unconstrained. Binary evolution theory predicts that the Hertzsprung gap is home to multiple populations of binary systems with varied evolutionary histories. In this paper, we develop a method to distinguish single YSGs from YSG plus O- or B-type main-sequence binaries using optical and ultraviolet photometry, and then apply this method to identify candidate YSG binaries in the Magellanic Clouds. After constructing a set of combined stellar atmosphere models, we find that optical photometry is, given typical measurement and reddening uncertainties, sufficient to discern single YSGs from YSG+OB binaries if the OB-star is at least ∼5M⊙ for Teff,YSG ∼ 4000 K, but requires a ∼20M⊙ OB star for YSGs up to Teff,YSG ∼ 9000 K. For these hotter YSG temperatures, ultraviolet photometry allows binaries with OB companions as small as ∼7M⊙ to be identified. We use color–color spaces developed from these models to search for evidence of excess blue or ultraviolet light in a set of ∼1000 YSG candidates in the Magellanic Clouds. We identify hundreds of candidate YSG binary systems and report a preliminary fraction of YSGs that show a blue/UV color excess of 20%–60%. Spectroscopic follow-up is now required to confirm the true nature of this population. acknowledgement: "The authors thank Aaron Tohuvavohu, Katie Breivik, Marten van Kerkwijk, Jakub Klencki, Eva Laplace, and Dae-Sik Moon for helpful discussions, and Adiv Paradise for helpful edits. The authors also thank the anonymous reviewer for a helpful and constructive referee report.\r\nThe authors at the University of Toronto acknowledge that the land on which the University of Toronto operates is the traditional territory of the Huron–Wendat, the Seneca, and the Mississaugas of the Credit River. They are grateful to have the opportunity to work on this land.\r\nThe Dunlap Institute is funded through an endowment established by the David Dunlap family and the University of Toronto.\r\nA.J.G.O. is supported by a McWilliams Fellowship at Carnegie Mellon University. M.R.D. acknowledges support from the NSERC through grant RGPIN-2019-06186, the Canada Research Chairs Program, and the Dunlap Institute at the University of Toronto. B.M.G. acknowledges the support of the Natural Sciences and Engineering Research Council of Canada (NSERC) through grant RGPIN-2022-03163, and of the Canada Research Chairs program. Support for this work was provided by NASA through the NASA Hubble Fellowship Program grant Nos. HST-HF2-51457.001-A and HST-HF2-51516 awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., for NASA, under contract NAS5-26555.\r\nThis research has made use of the SIMBAD database (M. Wenger et al. 2000), operated at CDS, Strasbourg, France, and the SVO Filter Profile Service 13 supported by the Spanish MINECO through grant AYA2017-84089 (C. Rodrigo et al. 2012, 2020).\r\nThis research has made use of the following software: astropy (Astropy Collaboration et al. 2013, 2018, 2022), IRAF (D. Tody 1986, 1993), and TOPCAT (M. B. Taylor 2005)." article_number: '29' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Anna J.G. full_name: O’Grady, Anna J.G. last_name: O’Grady - first_name: Maria R. full_name: Drout, Maria R. last_name: Drout - first_name: Kathryn F. full_name: Neugent, Kathryn F. last_name: Neugent - first_name: Bethany full_name: Ludwig, Bethany last_name: Ludwig - first_name: Ylva Louise Linsdotter full_name: Götberg, Ylva Louise Linsdotter id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d last_name: Götberg orcid: 0000-0002-6960-6911 - first_name: B. M. full_name: Gaensler, B. M. last_name: Gaensler citation: ama: O’Grady AJG, Drout MR, Neugent KF, Ludwig B, Götberg YLL, Gaensler BM. Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. 2024;975. doi:10.3847/1538-4357/ad778a apa: O’Grady, A. J. G., Drout, M. R., Neugent, K. F., Ludwig, B., Götberg, Y. L. L., & Gaensler, B. M. (2024). Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. IOP Publishing. https://doi.org/10.3847/1538-4357/ad778a chicago: O’Grady, Anna J.G., Maria R. Drout, Kathryn F. Neugent, Bethany Ludwig, Ylva Louise Linsdotter Götberg, and B. M. Gaensler. “Binary Yellow Supergiants in the Magellanic Clouds. I. Photometric Candidate Identification.” Astrophysical Journal. IOP Publishing, 2024. https://doi.org/10.3847/1538-4357/ad778a. ieee: A. J. G. O’Grady, M. R. Drout, K. F. Neugent, B. Ludwig, Y. L. L. Götberg, and B. M. Gaensler, “Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification,” Astrophysical Journal, vol. 975. IOP Publishing, 2024. ista: O’Grady AJG, Drout MR, Neugent KF, Ludwig B, Götberg YLL, Gaensler BM. 2024. Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification. Astrophysical Journal. 975, 29. mla: O’Grady, Anna J. G., et al. “Binary Yellow Supergiants in the Magellanic Clouds. I. Photometric Candidate Identification.” Astrophysical Journal, vol. 975, 29, IOP Publishing, 2024, doi:10.3847/1538-4357/ad778a. short: A.J.G. O’Grady, M.R. Drout, K.F. Neugent, B. Ludwig, Y.L.L. Götberg, B.M. Gaensler, Astrophysical Journal 975 (2024). date_created: 2024-11-10T23:01:59Z date_published: 2024-11-01T00:00:00Z date_updated: 2025-09-08T14:37:18Z day: '01' ddc: - '520' department: - _id: YlGo doi: 10.3847/1538-4357/ad778a external_id: arxiv: - '2406.17177' isi: - '001339486900001' file: - access_level: open_access checksum: 0e9bb88b5048ecc782ac27953c84b8ce content_type: application/pdf creator: dernst date_created: 2024-11-11T09:20:45Z date_updated: 2024-11-11T09:20:45Z file_id: '18535' file_name: 2024_AstrophysicalJour_Grady.pdf file_size: 34634395 relation: main_file success: 1 file_date_updated: 2024-11-11T09:20:45Z has_accepted_license: '1' intvolume: ' 975' isi: 1 language: - iso: eng month: '11' oa: 1 oa_version: Published Version publication: Astrophysical Journal publication_identifier: eissn: - 1538-4357 issn: - 0004-637X publication_status: published publisher: IOP Publishing quality_controlled: '1' scopus_import: '1' status: public title: Binary yellow supergiants in the Magellanic Clouds. I. Photometric candidate identification tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 975 year: '2024' ... --- APC_amount: 3062,93 EUR OA_place: publisher OA_type: hybrid _id: '18525' abstract: - lang: eng text: As their statistical power grows, genome-wide association studies (GWAS) have identified an increasing number of loci underlying quantitative traits of interest. These loci are scattered throughout the genome and are individually responsible only for small fractions of the total heritable trait variance. The recently proposed omnigenic model provides a conceptual framework to explain these observations by postulating that numerous distant loci contribute to each complex trait via effect propagation through intracellular regulatory networks. We formalize this conceptual framework by proposing the “quantitative omnigenic model” (QOM), a statistical model that combines prior knowledge of the regulatory network topology with genomic data. By applying our model to gene expression traits in yeast, we demonstrate that QOM achieves similar gene expression prediction performance to traditional GWAS with hundreds of times less parameters, while simultaneously extracting candidate causal and quantitative chains of effect propagation through the regulatory network for every individual gene. We estimate the fraction of heritable trait variance in cis- and in trans-, break the latter down by effect propagation order, assess the trans- variance not attributable to transcriptional regulation, and show that QOM correctly accounts for the low-dimensional structure of gene expression covariance. We furthermore demonstrate the relevance of QOM for systems biology, by employing it as a statistical test for the quality of regulatory network reconstructions, and linking it to the propagation of nontranscriptional (including environmental) effects. acknowledgement: N.R.acknowledges the support of the Austrian Academy of Sciences through the Doctoral Fellowship Programme (DOC) of the Austrian Academy of Sciences 26917. M.H. and G.T. were supported in part by the Human Frontiers Science Program Grant RGP0034/2018. We thank Nicholas H. Barton, Fyodor Kondrashov, and Matthew R. Robinson for fruitful discussions. article_number: e2402340121 article_processing_charge: Yes article_type: original author: - first_name: Natalia full_name: Ruzickova, Natalia id: D2761128-D73D-11E9-A1BF-BA0DE6697425 last_name: Ruzickova - first_name: Michal full_name: Hledik, Michal id: 4171253A-F248-11E8-B48F-1D18A9856A87 last_name: Hledik - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 citation: ama: Ruzickova N, Hledik M, Tkačik G. Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(44). doi:10.1073/pnas.2402340121 apa: Ruzickova, N., Hledik, M., & Tkačik, G. (2024). Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2402340121 chicago: Ruzickova, Natalia, Michal Hledik, and Gašper Tkačik. “Quantitative Omnigenic Model Discovers Interpretable Genome-Wide Associations.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2402340121. ieee: N. Ruzickova, M. Hledik, and G. Tkačik, “Quantitative omnigenic model discovers interpretable genome-wide associations,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44. National Academy of Sciences, 2024. ista: Ruzickova N, Hledik M, Tkačik G. 2024. Quantitative omnigenic model discovers interpretable genome-wide associations. Proceedings of the National Academy of Sciences of the United States of America. 121(44), e2402340121. mla: Ruzickova, Natalia, et al. “Quantitative Omnigenic Model Discovers Interpretable Genome-Wide Associations.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44, e2402340121, National Academy of Sciences, 2024, doi:10.1073/pnas.2402340121. short: N. Ruzickova, M. Hledik, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). corr_author: '1' date_created: 2024-11-10T23:01:59Z date_published: 2024-10-29T00:00:00Z date_updated: 2026-04-07T12:02:39Z day: '29' ddc: - '570' department: - _id: GaTk - _id: NiBa doi: 10.1073/pnas.2402340121 external_id: isi: - '001349462600001' pmid: - '39441639' file: - access_level: open_access checksum: d930e2ccf9ec900c7d7509a78cfb3564 content_type: application/pdf creator: dernst date_created: 2024-11-11T09:31:00Z date_updated: 2024-11-11T09:31:00Z file_id: '18536' file_name: 2024_PNAS_Ruzickova.pdf file_size: 25529709 relation: main_file success: 1 file_date_updated: 2024-11-11T09:31:00Z has_accepted_license: '1' intvolume: ' 121' isi: 1 issue: '44' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 7bec9174-9f16-11ee-852c-ded9fe5f810e name: Collective behaviour of cells in pancreatic Islets of Langerhans - _id: 2665AAFE-B435-11E9-9278-68D0E5697425 grant_number: RGP0034/2018 name: Can evolution minimize spurious signaling crosstalk to reach optimal performance? publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' related_material: record: - id: '20357' relation: dissertation_contains status: public scopus_import: '1' status: public title: Quantitative omnigenic model discovers interpretable genome-wide associations tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 121 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18526' abstract: - lang: eng text: Multivesicular endosomes (MVEs) sequester membrane proteins destined for degradation within intralumenal vesicles (ILVs), a process mediated by the membrane-remodeling action of Endosomal Sorting Complex Required for Transport (ESCRT) proteins. In Arabidopsis, endosomal membrane constriction and scission are uncoupled, resulting in the formation of extensive concatenated ILV networks and enhancing cargo sequestration efficiency. Here, we used a combination of electron tomography, computer simulations, and mathematical modeling to address the questions of when concatenated ILV networks evolved in plants and what drives their formation. Through morphometric analyses of tomographic reconstructions of endosomes across yeast, algae, and various land plants, we have found that ILV concatenation is widespread within plant species, but only prevalent in seed plants, especially in flowering plants. Multiple budding sites that require the formation of pores in the limiting membrane were only identified in hornworts and seed plants, suggesting that this mechanism has evolved independently in both plant lineages. To identify the conditions under which these multiple budding sites can arise, we used particle-based molecular dynamics simulations and found that changes in ESCRT filament properties, such as filament curvature and membrane binding energy, can generate the membrane shapes observed in multiple budding sites. To understand the relationship between membrane budding activity and ILV network topology, we performed computational simulations and identified a set of membrane remodeling parameters that can recapitulate our tomographic datasets. acknowledgement: We would like to thank Janice Pennington for her support with electron tomography data collection, Dr. Ingrid Jordon-Thaden, director of the Botany Garden and Greenhouse of University of Wisconsin Madison, for her invaluable assistance collecting plant materials, Dr. Marie Trest for providing Chara specimens, and Dr. Nicholas Keuler for his advice on statistical analyses. We thank Charlie Hamilton for exploring the initial computational model. This work was supported by grant NSF MCB 2114603 and NIH 1S10OD026769-01 to M.S.O. F.F acknowledges support as a NOMIS Fellow from the NOMIS Foundation. A.Š. acknowledges ERC Starting Grant “NEPA” 802960. article_number: e2409407121 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Ethan full_name: Weiner, Ethan last_name: Weiner - first_name: Elizabeth full_name: Berryman, Elizabeth last_name: Berryman - first_name: Felix F full_name: Frey, Felix F id: a0270b37-8f1a-11ec-95c7-8e710c59a4f3 last_name: Frey orcid: 0000-0001-8501-6017 - first_name: Ariadna González full_name: Solís, Ariadna González last_name: Solís - first_name: André full_name: Leier, André last_name: Leier - first_name: Tatiana Marquez full_name: Lago, Tatiana Marquez last_name: Lago - first_name: Anđela full_name: Šarić, Anđela id: bf63d406-f056-11eb-b41d-f263a6566d8b last_name: Šarić orcid: 0000-0002-7854-2139 - first_name: Marisa S. full_name: Otegui, Marisa S. last_name: Otegui citation: ama: Weiner E, Berryman E, Frey FF, et al. Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(44). doi:10.1073/pnas.2409407121 apa: Weiner, E., Berryman, E., Frey, F. F., Solís, A. G., Leier, A., Lago, T. M., … Otegui, M. S. (2024). Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.2409407121 chicago: Weiner, Ethan, Elizabeth Berryman, Felix F Frey, Ariadna González Solís, André Leier, Tatiana Marquez Lago, Anđela Šarić, and Marisa S. Otegui. “Endosomal Membrane Budding Patterns in Plants.” Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2409407121. ieee: E. Weiner et al., “Endosomal membrane budding patterns in plants,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44. National Academy of Sciences, 2024. ista: Weiner E, Berryman E, Frey FF, Solís AG, Leier A, Lago TM, Šarić A, Otegui MS. 2024. Endosomal membrane budding patterns in plants. Proceedings of the National Academy of Sciences of the United States of America. 121(44), e2409407121. mla: Weiner, Ethan, et al. “Endosomal Membrane Budding Patterns in Plants.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 44, e2409407121, National Academy of Sciences, 2024, doi:10.1073/pnas.2409407121. short: E. Weiner, E. Berryman, F.F. Frey, A.G. Solís, A. Leier, T.M. Lago, A. Šarić, M.S. Otegui, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). date_created: 2024-11-10T23:01:59Z date_published: 2024-10-29T00:00:00Z date_updated: 2025-09-08T14:38:35Z day: '29' ddc: - '570' department: - _id: AnSa doi: 10.1073/pnas.2409407121 ec_funded: 1 external_id: isi: - '001349500800007' pmid: - '39441629' file: - access_level: open_access checksum: 21c82d2ab58ff99b2bd0489797be42e5 content_type: application/pdf creator: dernst date_created: 2024-11-11T09:35:15Z date_updated: 2024-11-11T09:35:15Z file_id: '18538' file_name: 2024_PNAS_Weiner.pdf file_size: 5268074 relation: main_file success: 1 file_date_updated: 2024-11-11T09:35:15Z has_accepted_license: '1' intvolume: ' 121' isi: 1 issue: '44' language: - iso: eng month: '10' oa: 1 oa_version: Published Version pmid: 1 project: - _id: eba2549b-77a9-11ec-83b8-a81e493eae4e call_identifier: H2020 grant_number: '802960' name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines' publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences quality_controlled: '1' scopus_import: '1' status: public title: Endosomal membrane budding patterns in plants tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 121 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18527' abstract: - lang: eng text: "Context. Galaxies evolve through a dynamic exchange of material with their immediate surrounding environment, the so-called circumgalactic medium (CGM). Understanding the physics of gas flows and the nature of the CGM is fundamental to studying galaxy evolution, especially at 4 ≤ z ≤ 6 (i.e., after the Epoch of Reionization) when galaxies rapidly assembled their masses and reached their chemical maturity. Galactic outflows are predicted to enrich the CGM with metals, although it has also been suggested that gas stripping in systems undergoing a major merger may play a role.\r\n\r\nAims. In this work, we explore the metal enrichment of the medium around merging galaxies at z ∼ 4.5, observed by the ALMA Large Program to INvestigate [CII] at Early times (ALPINE). To do so, we study the nature of the [CII] 158 μm emission in the CGM around these systems, using simulations to help disentangle the mechanisms contributing to the CGM metal pollution.\r\n\r\nMethods. By adopting an updated classification of major merger systems in the ALPINE survey, we selected and analyzed merging galaxies whose components can be spatially and/or spectrally resolved in a robust way. This makes it possible to distinguish between the [CII] emission coming from the single components of the system and that coming from the system as a whole. We also made use of the dustyGadget cosmological simulation to select synthetic analogs of observed galaxies and guide the interpretation of the observational results.\r\n\r\nResults. We find a large diffuse [CII] envelope (≳20 kpc) embedding all the merging systems, with at least 25% of the total [CII] emission coming from the medium between the galaxies. Using predictions from dustyGadget, we suggest that this emission has a multi-fold nature, with dynamical interactions between galaxies playing a major role in stripping the gas and enriching the medium with heavy elements." acknowledgement: 'The authors would like to thank the anonymous referee for the useful suggestions which improved this article. This paper is based on data obtained with the ALMA Observatory, under Large Program 2017.1.00428.L. ALMA is a partnership of ESO (representing its member states), NSF (USA), and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. CDC would like to thank the GESO group at the European Southern Observatory (ESO) for the useful discussions while preparing this manuscript. The simulated data underlying this article will be shared on reasonable request to the corresponding author. CDC acknowledged support from Sapienza University of Rome program “Bando per la mobilità individuale all’estero” (DR n.1607 del 14 June 2021) during the visiting period (June-November 2022) at ESO Garching, Germany. LG and RS acknowledge support from the PRIN 2022 MUR project 2022CB3PJ3 – First Light And Galaxy aSsembly (FLAGS) funded by the European Union – Next Generation EU, and from the Amaldi Research Center funded by the MIUR program “Dipartimento di Eccellenza” (CUP:B81I18001170001). MR acknowledges support from the Narodowe Centrum Nauki (UMO-2020/38/E/ST9/00077) and support from the Foundation for Polish Science (FNP) under the program START 063.2023. We have benefited from the publicly available software CASA and CARTA and programming language Python, including the numpy (https://numpy.org), matplotlib (https://matplotlib.org), scipy (https://scipy.org) and astropy (http://www.astropy.org) packages. ' article_number: A255 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Claudia full_name: Di Cesare, Claudia id: 2d002343-372f-11ef-98ec-a164d20427cb last_name: Di Cesare - first_name: M. full_name: Ginolfi, M. last_name: Ginolfi - first_name: L. full_name: Graziani, L. last_name: Graziani - first_name: R. full_name: Schneider, R. last_name: Schneider - first_name: M. full_name: Romano, M. last_name: Romano - first_name: G. full_name: Popping, G. last_name: Popping citation: ama: Di Cesare C, Ginolfi M, Graziani L, Schneider R, Romano M, Popping G. Carbon envelopes around merging galaxies at z ~ 4.5. Astronomy and Astrophysics. 2024;690. doi:10.1051/0004-6361/202449164 apa: Di Cesare, C., Ginolfi, M., Graziani, L., Schneider, R., Romano, M., & Popping, G. (2024). Carbon envelopes around merging galaxies at z ~ 4.5. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202449164 chicago: Di Cesare, Claudia, M. Ginolfi, L. Graziani, R. Schneider, M. Romano, and G. Popping. “Carbon Envelopes around Merging Galaxies at z ~ 4.5.” Astronomy and Astrophysics. EDP Sciences, 2024. https://doi.org/10.1051/0004-6361/202449164. ieee: C. Di Cesare, M. Ginolfi, L. Graziani, R. Schneider, M. Romano, and G. Popping, “Carbon envelopes around merging galaxies at z ~ 4.5,” Astronomy and Astrophysics, vol. 690. EDP Sciences, 2024. ista: Di Cesare C, Ginolfi M, Graziani L, Schneider R, Romano M, Popping G. 2024. Carbon envelopes around merging galaxies at z ~ 4.5. Astronomy and Astrophysics. 690, A255. mla: Di Cesare, Claudia, et al. “Carbon Envelopes around Merging Galaxies at z ~ 4.5.” Astronomy and Astrophysics, vol. 690, A255, EDP Sciences, 2024, doi:10.1051/0004-6361/202449164. short: C. Di Cesare, M. Ginolfi, L. Graziani, R. Schneider, M. Romano, G. Popping, Astronomy and Astrophysics 690 (2024). corr_author: '1' date_created: 2024-11-10T23:02:00Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:35:57Z day: '01' ddc: - '520' department: - _id: JoMa doi: 10.1051/0004-6361/202449164 external_id: arxiv: - '2401.03020' isi: - '001332213700013' file: - access_level: open_access checksum: 24c65a64047aba156f39b01425269bdb content_type: application/pdf creator: dernst date_created: 2024-11-11T08:54:11Z date_updated: 2024-11-11T08:54:11Z file_id: '18533' file_name: 2024_AstronomyAstrophysics_diCesare.pdf file_size: 8033864 relation: main_file success: 1 file_date_updated: 2024-11-11T08:54:11Z has_accepted_license: '1' intvolume: ' 690' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version publication: Astronomy and Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: Carbon envelopes around merging galaxies at z ~ 4.5 tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 690 year: '2024' ... --- OA_place: publisher OA_type: hybrid _id: '18528' abstract: - lang: eng text: The recent measurement of magnetic field strength inside the radiative interior of red giant stars has opened the way toward full 3D characterization of the geometry of stable large-scale magnetic fields. However, current measurements, which are limited to dipolar (ℓ = 1) mixed modes, do not properly constrain the topology of magnetic fields due to degeneracies on the observed magnetic field signature on such ℓ = 1 mode frequencies. Efforts focused toward unambiguous detections of magnetic field configurations are now key to better understand angular momentum transport in stars. We investigated the detectability of complex magnetic field topologies (such as the ones observed at the surface of stars with a radiative envelope with spectropolarimetry) inside the radiative interior of red giants. We focused on a field composed of a combination of a dipole and a quadrupole (quadrudipole) and on an offset field. We explored the potential of probing such magnetic field topologies from a combined measurement of magnetic signatures on ℓ = 1 and quadrupolar (ℓ = 2) mixed mode oscillation frequencies. We first derived the asymptotic theoretical formalism for computing the asymmetric signature in the frequency pattern for ℓ = 2 modes due to a quadrudipole magnetic field. To access asymmetry parameters for more complex magnetic field topologies, we numerically performed a grid search over the parameter space to map the degeneracy of the signatures of given topologies. We demonstrate the crucial role played by ℓ = 2 mixed modes in accessing internal magnetic fields with a quadrupolar component. The degeneracy of the quadrudipole compared to pure dipolar fields is lifted when considering magnetic asymmetries in both ℓ = 1 and ℓ = 2 mode frequencies. In addition to the analytical derivation for the quadrudipole, we present the prospect for complex magnetic field inversions using magnetic sensitivity kernels from standard perturbation analysis for forward modeling. Using this method, we explored the detectability of offset magnetic fields from ℓ = 1 and ℓ = 2 frequencies and demonstrate that offset fields may be mistaken for weak and centered magnetic fields, resulting in underestimating the magnetic field strength in stellar cores. We emphasize the need to characterize ℓ = 2 mixed-mode frequencies, (along with the currently characterized ℓ = 1 mixed modes), to unveil the higher-order components of the geometry of buried magnetic fields and to better constrain angular momentum transport inside stars. acknowledgement: The authors thank S. Mathis, L. Barrault, S. Torres, A. Cristea, and K. M. Smith for very useful discussions. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curíe grant agreement No 101034413. The authors thank the anonymous referee for valuable comments and suggestions to improve the manuscript. article_number: A217 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Srijan B full_name: Das, Srijan B id: 9ce7c423-dacf-11ed-8942-e09c6cb27149 last_name: Das orcid: 0000-0003-0896-7972 - first_name: Lukas full_name: Einramhof, Lukas id: f1497a1a-72ef-11ef-b75a-fd877bbf6e8c last_name: Einramhof - first_name: Lisa Annabelle full_name: Bugnet, Lisa Annabelle id: d9edb345-f866-11ec-9b37-d119b5234501 last_name: Bugnet orcid: 0000-0003-0142-4000 citation: ama: Das SB, Einramhof L, Bugnet LA. Unveiling complex magnetic field configurations in red giant stars. Astronomy and Astrophysics. 2024;690. doi:10.1051/0004-6361/202450918 apa: Das, S. B., Einramhof, L., & Bugnet, L. A. (2024). Unveiling complex magnetic field configurations in red giant stars. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202450918 chicago: Das, Srijan B, Lukas Einramhof, and Lisa Annabelle Bugnet. “Unveiling Complex Magnetic Field Configurations in Red Giant Stars.” Astronomy and Astrophysics. EDP Sciences, 2024. https://doi.org/10.1051/0004-6361/202450918. ieee: S. B. Das, L. Einramhof, and L. A. Bugnet, “Unveiling complex magnetic field configurations in red giant stars,” Astronomy and Astrophysics, vol. 690. EDP Sciences, 2024. ista: Das SB, Einramhof L, Bugnet LA. 2024. Unveiling complex magnetic field configurations in red giant stars. Astronomy and Astrophysics. 690, A217. mla: Das, Srijan B., et al. “Unveiling Complex Magnetic Field Configurations in Red Giant Stars.” Astronomy and Astrophysics, vol. 690, A217, EDP Sciences, 2024, doi:10.1051/0004-6361/202450918. short: S.B. Das, L. Einramhof, L.A. Bugnet, Astronomy and Astrophysics 690 (2024). corr_author: '1' date_created: 2024-11-10T23:02:00Z date_published: 2024-10-01T00:00:00Z date_updated: 2025-09-08T14:36:39Z day: '01' ddc: - '520' department: - _id: LiBu doi: 10.1051/0004-6361/202450918 ec_funded: 1 external_id: arxiv: - '2405.20133' isi: - '001336485200015' file: - access_level: open_access checksum: d43bbe6ed8ce4512e65e2d0d87070cf6 content_type: application/pdf creator: dernst date_created: 2024-11-11T09:01:11Z date_updated: 2024-11-11T09:01:11Z file_id: '18534' file_name: 2024_AstronomyAstrophysics_Das.pdf file_size: 5306256 relation: main_file success: 1 file_date_updated: 2024-11-11T09:01:11Z has_accepted_license: '1' intvolume: ' 690' isi: 1 language: - iso: eng month: '10' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Astronomy and Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: Unveiling complex magnetic field configurations in red giant stars tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345 volume: 690 year: '2024' ...