---
_id: '14701'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Lynden A.
  full_name: Archer, Lynden A.
  last_name: Archer
- first_name: Peter G.
  full_name: Bruce, Peter G.
  last_name: Bruce
- first_name: Ernesto J.
  full_name: Calvo, Ernesto J.
  last_name: Calvo
- first_name: Daniel
  full_name: Dewar, Daniel
  last_name: Dewar
- first_name: James H. J.
  full_name: Ellison, James H. J.
  last_name: Ellison
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
- first_name: Xiangwen
  full_name: Gao, Xiangwen
  last_name: Gao
- first_name: Laurence J.
  full_name: Hardwick, Laurence J.
  last_name: Hardwick
- first_name: Gabriela
  full_name: Horwitz, Gabriela
  last_name: Horwitz
- first_name: Jürgen
  full_name: Janek, Jürgen
  last_name: Janek
- first_name: Lee R.
  full_name: Johnson, Lee R.
  last_name: Johnson
- first_name: Jack W.
  full_name: Jordan, Jack W.
  last_name: Jordan
- first_name: Shoichi
  full_name: Matsuda, Shoichi
  last_name: Matsuda
- first_name: Svetlana
  full_name: Menkin, Svetlana
  last_name: Menkin
- first_name: Soumyadip
  full_name: Mondal, Soumyadip
  id: d25d21ef-dc8d-11ea-abe3-ec4576307f48
  last_name: Mondal
- first_name: Qianyuan
  full_name: Qiu, Qianyuan
  last_name: Qiu
- first_name: Thukshan
  full_name: Samarakoon, Thukshan
  last_name: Samarakoon
- first_name: Israel
  full_name: Temprano, Israel
  last_name: Temprano
- first_name: Kohei
  full_name: Uosaki, Kohei
  last_name: Uosaki
- first_name: Ganesh
  full_name: Vailaya, Ganesh
  last_name: Vailaya
- first_name: Eric D.
  full_name: Wachsman, Eric D.
  last_name: Wachsman
- first_name: Yiying
  full_name: Wu, Yiying
  last_name: Wu
- first_name: Shen
  full_name: Ye, Shen
  last_name: Ye
citation:
  ama: 'Archer LA, Bruce PG, Calvo EJ, et al. Towards practical metal–oxygen batteries:
    General discussion. <i>Faraday Discussions</i>. 2024;248:392-411. doi:<a href="https://doi.org/10.1039/d3fd90062b">10.1039/d3fd90062b</a>'
  apa: 'Archer, L. A., Bruce, P. G., Calvo, E. J., Dewar, D., Ellison, J. H. J., Freunberger,
    S. A., … Ye, S. (2024). Towards practical metal–oxygen batteries: General discussion.
    <i>Faraday Discussions</i>. Royal Society of Chemistry. <a href="https://doi.org/10.1039/d3fd90062b">https://doi.org/10.1039/d3fd90062b</a>'
  chicago: 'Archer, Lynden A., Peter G. Bruce, Ernesto J. Calvo, Daniel Dewar, James
    H. J. Ellison, Stefan Alexander Freunberger, Xiangwen Gao, et al. “Towards Practical
    Metal–Oxygen Batteries: General Discussion.” <i>Faraday Discussions</i>. Royal
    Society of Chemistry, 2024. <a href="https://doi.org/10.1039/d3fd90062b">https://doi.org/10.1039/d3fd90062b</a>.'
  ieee: 'L. A. Archer <i>et al.</i>, “Towards practical metal–oxygen batteries: General
    discussion,” <i>Faraday Discussions</i>, vol. 248. Royal Society of Chemistry,
    pp. 392–411, 2024.'
  ista: 'Archer LA, Bruce PG, Calvo EJ, Dewar D, Ellison JHJ, Freunberger SA, Gao
    X, Hardwick LJ, Horwitz G, Janek J, Johnson LR, Jordan JW, Matsuda S, Menkin S,
    Mondal S, Qiu Q, Samarakoon T, Temprano I, Uosaki K, Vailaya G, Wachsman ED, Wu
    Y, Ye S. 2024. Towards practical metal–oxygen batteries: General discussion. Faraday
    Discussions. 248, 392–411.'
  mla: 'Archer, Lynden A., et al. “Towards Practical Metal–Oxygen Batteries: General
    Discussion.” <i>Faraday Discussions</i>, vol. 248, Royal Society of Chemistry,
    2024, pp. 392–411, doi:<a href="https://doi.org/10.1039/d3fd90062b">10.1039/d3fd90062b</a>.'
  short: L.A. Archer, P.G. Bruce, E.J. Calvo, D. Dewar, J.H.J. Ellison, S.A. Freunberger,
    X. Gao, L.J. Hardwick, G. Horwitz, J. Janek, L.R. Johnson, J.W. Jordan, S. Matsuda,
    S. Menkin, S. Mondal, Q. Qiu, T. Samarakoon, I. Temprano, K. Uosaki, G. Vailaya,
    E.D. Wachsman, Y. Wu, S. Ye, Faraday Discussions 248 (2024) 392–411.
date_created: 2023-12-20T10:48:09Z
date_published: 2024-01-29T00:00:00Z
date_updated: 2025-09-04T11:34:30Z
day: '29'
department:
- _id: StFr
doi: 10.1039/d3fd90062b
external_id:
  isi:
  - '001130090400001'
  pmid:
  - '38112202'
intvolume: '       248'
isi: 1
keyword:
- Physical and Theoretical Chemistry
language:
- iso: eng
month: '01'
oa_version: None
page: 392-411
pmid: 1
publication: Faraday Discussions
publication_identifier:
  eissn:
  - 1364-5498
  issn:
  - 1359-6640
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Towards practical metal–oxygen batteries: General discussion'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 248
year: '2024'
...
---
_id: '14702'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Gary A.
  full_name: Attard, Gary A.
  last_name: Attard
- first_name: Ernesto J.
  full_name: Calvo, Ernesto J.
  last_name: Calvo
- first_name: Larry A.
  full_name: Curtiss, Larry A.
  last_name: Curtiss
- first_name: Daniel
  full_name: Dewar, Daniel
  last_name: Dewar
- first_name: James H. J.
  full_name: Ellison, James H. J.
  last_name: Ellison
- first_name: Xiangwen
  full_name: Gao, Xiangwen
  last_name: Gao
- first_name: Clare P.
  full_name: Grey, Clare P.
  last_name: Grey
- first_name: Laurence J.
  full_name: Hardwick, Laurence J.
  last_name: Hardwick
- first_name: Gabriela
  full_name: Horwitz, Gabriela
  last_name: Horwitz
- first_name: Juergen
  full_name: Janek, Juergen
  last_name: Janek
- first_name: Lee R.
  full_name: Johnson, Lee R.
  last_name: Johnson
- first_name: Jack W.
  full_name: Jordan, Jack W.
  last_name: Jordan
- first_name: Shoichi
  full_name: Matsuda, Shoichi
  last_name: Matsuda
- first_name: Soumyadip
  full_name: Mondal, Soumyadip
  id: d25d21ef-dc8d-11ea-abe3-ec4576307f48
  last_name: Mondal
- first_name: Alex R.
  full_name: Neale, Alex R.
  last_name: Neale
- first_name: Nagore
  full_name: Ortiz-Vitoriano, Nagore
  last_name: Ortiz-Vitoriano
- first_name: Israel
  full_name: Temprano, Israel
  last_name: Temprano
- first_name: Ganesh
  full_name: Vailaya, Ganesh
  last_name: Vailaya
- first_name: Eric D.
  full_name: Wachsman, Eric D.
  last_name: Wachsman
- first_name: Hsien-Hau
  full_name: Wang, Hsien-Hau
  last_name: Wang
- first_name: Yiying
  full_name: Wu, Yiying
  last_name: Wu
- first_name: Shen
  full_name: Ye, Shen
  last_name: Ye
citation:
  ama: 'Attard GA, Calvo EJ, Curtiss LA, et al. Materials for stable metal–oxygen
    battery cathodes: general discussion. <i>Faraday Discussions</i>. 2024;248:75-88.
    doi:<a href="https://doi.org/10.1039/d3fd90059b">10.1039/d3fd90059b</a>'
  apa: 'Attard, G. A., Calvo, E. J., Curtiss, L. A., Dewar, D., Ellison, J. H. J.,
    Gao, X., … Ye, S. (2024). Materials for stable metal–oxygen battery cathodes:
    general discussion. <i>Faraday Discussions</i>. Royal Society of Chemistry. <a
    href="https://doi.org/10.1039/d3fd90059b">https://doi.org/10.1039/d3fd90059b</a>'
  chicago: 'Attard, Gary A., Ernesto J. Calvo, Larry A. Curtiss, Daniel Dewar, James
    H. J. Ellison, Xiangwen Gao, Clare P. Grey, et al. “Materials for Stable Metal–Oxygen
    Battery Cathodes: General Discussion.” <i>Faraday Discussions</i>. Royal Society
    of Chemistry, 2024. <a href="https://doi.org/10.1039/d3fd90059b">https://doi.org/10.1039/d3fd90059b</a>.'
  ieee: 'G. A. Attard <i>et al.</i>, “Materials for stable metal–oxygen battery cathodes:
    general discussion,” <i>Faraday Discussions</i>, vol. 248. Royal Society of Chemistry,
    pp. 75–88, 2024.'
  ista: 'Attard GA, Calvo EJ, Curtiss LA, Dewar D, Ellison JHJ, Gao X, Grey CP, Hardwick
    LJ, Horwitz G, Janek J, Johnson LR, Jordan JW, Matsuda S, Mondal S, Neale AR,
    Ortiz-Vitoriano N, Temprano I, Vailaya G, Wachsman ED, Wang H-H, Wu Y, Ye S. 2024.
    Materials for stable metal–oxygen battery cathodes: general discussion. Faraday
    Discussions. 248, 75–88.'
  mla: 'Attard, Gary A., et al. “Materials for Stable Metal–Oxygen Battery Cathodes:
    General Discussion.” <i>Faraday Discussions</i>, vol. 248, Royal Society of Chemistry,
    2024, pp. 75–88, doi:<a href="https://doi.org/10.1039/d3fd90059b">10.1039/d3fd90059b</a>.'
  short: G.A. Attard, E.J. Calvo, L.A. Curtiss, D. Dewar, J.H.J. Ellison, X. Gao,
    C.P. Grey, L.J. Hardwick, G. Horwitz, J. Janek, L.R. Johnson, J.W. Jordan, S.
    Matsuda, S. Mondal, A.R. Neale, N. Ortiz-Vitoriano, I. Temprano, G. Vailaya, E.D.
    Wachsman, H.-H. Wang, Y. Wu, S. Ye, Faraday Discussions 248 (2024) 75–88.
date_created: 2023-12-20T10:49:43Z
date_published: 2024-01-29T00:00:00Z
date_updated: 2025-09-04T11:35:09Z
day: '29'
department:
- _id: StFr
doi: 10.1039/d3fd90059b
external_id:
  isi:
  - '001130029600001'
  pmid:
  - '38109098'
intvolume: '       248'
isi: 1
keyword:
- Physical and Theoretical Chemistry
language:
- iso: eng
month: '01'
oa_version: None
page: 75-88
pmid: 1
publication: Faraday Discussions
publication_identifier:
  eissn:
  - 1364-5498
  issn:
  - 1359-6640
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Materials for stable metal–oxygen battery cathodes: general discussion'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 248
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14703'
abstract:
- lang: eng
  text: We present a discretization of the dynamic optimal transport problem for which
    we can obtain the convergence rate for the value of the transport cost to its
    continuous value when the temporal and spatial stepsize vanish. This convergence
    result does not require any regularity assumption on the measures, though experiments
    suggest that the rate is not sharp. Via an analysis of the duality gap we also
    obtain the convergence rates for the gradient of the optimal potentials and the
    velocity field under mild regularity assumptions. To obtain such rates we discretize
    the dual formulation of the dynamic optimal transport problem and use the mature
    literature related to the error due to discretizing the Hamilton-Jacobi equation.
acknowledgement: 'The authors would like to thank Chris Wojtan for his continuous
  support and several interesting discussions. Part of this research was performed
  during two visits: one of SI to the BIDSA research center at Bocconi University,
  and one of HL to the Institute of Science and Technology Austria. Both host institutions
  are warmly acknowledged for the hospitality. HL is partially supported by the MUR-Prin
  2022-202244A7YL “Gradient Flows and Non-Smooth Geometric Structures with Applications
  to Optimization and Machine Learning”, funded by the European Union - Next Generation
  EU. SI is supported in part by ERC Consolidator Grant 101045083 “CoDiNA” funded
  by the European Research Council.'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Sadashige
  full_name: Ishida, Sadashige
  id: 6F7C4B96-A8E9-11E9-A7CA-09ECE5697425
  last_name: Ishida
  orcid: 0000-0002-3121-3100
- first_name: Hugo
  full_name: Lavenant, Hugo
  last_name: Lavenant
citation:
  ama: Ishida S, Lavenant H. Quantitative convergence of a discretization of dynamic
    optimal transport using the dual formulation. <i>Foundations of Computational
    Mathematics</i>. 2024. doi:<a href="https://doi.org/10.1007/s10208-024-09686-3">10.1007/s10208-024-09686-3</a>
  apa: Ishida, S., &#38; Lavenant, H. (2024). Quantitative convergence of a discretization
    of dynamic optimal transport using the dual formulation. <i>Foundations of Computational
    Mathematics</i>. Springer Nature. <a href="https://doi.org/10.1007/s10208-024-09686-3">https://doi.org/10.1007/s10208-024-09686-3</a>
  chicago: Ishida, Sadashige, and Hugo Lavenant. “Quantitative Convergence of a Discretization
    of Dynamic Optimal Transport Using the Dual Formulation.” <i>Foundations of Computational
    Mathematics</i>. Springer Nature, 2024. <a href="https://doi.org/10.1007/s10208-024-09686-3">https://doi.org/10.1007/s10208-024-09686-3</a>.
  ieee: S. Ishida and H. Lavenant, “Quantitative convergence of a discretization of
    dynamic optimal transport using the dual formulation,” <i>Foundations of Computational
    Mathematics</i>. Springer Nature, 2024.
  ista: Ishida S, Lavenant H. 2024. Quantitative convergence of a discretization of
    dynamic optimal transport using the dual formulation. Foundations of Computational
    Mathematics.
  mla: Ishida, Sadashige, and Hugo Lavenant. “Quantitative Convergence of a Discretization
    of Dynamic Optimal Transport Using the Dual Formulation.” <i>Foundations of Computational
    Mathematics</i>, Springer Nature, 2024, doi:<a href="https://doi.org/10.1007/s10208-024-09686-3">10.1007/s10208-024-09686-3</a>.
  short: S. Ishida, H. Lavenant, Foundations of Computational Mathematics (2024).
corr_author: '1'
date_created: 2023-12-21T10:14:37Z
date_published: 2024-11-11T00:00:00Z
date_updated: 2026-06-18T17:37:10Z
day: '11'
ddc:
- '000'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1007/s10208-024-09686-3
external_id:
  arxiv:
  - '2312.12213'
  isi:
  - '001352503300001'
isi: 1
keyword:
- Optimal transport
- Hamilton-Jacobi equation
- convex optimization
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s10208-024-09686-3
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: Foundations of Computational Mathematics
publication_identifier:
  eissn:
  - 1615-3383
  issn:
  - 1615-3375
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantitative convergence of a discretization of dynamic optimal transport using
  the dual formulation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14705'
abstract:
- lang: eng
  text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
    this lineage, and in particular the model species Artemia franciscana, has been
    the subject of extensive research. However, our understanding of the genetic mechanisms
    underlying various aspects of their reproductive biology, including sex determination,
    are still lacking. This is partly due to the scarcity of genomic resources for
    Artemia species and crustaceans in general. Here, we present a chromosome-level
    genome assembly of Artemia franciscana (Kellogg 1906), from the Great Salt Lake,
    USA. The genome is 1GB, and the majority of the genome (81%) is scaffolded into
    21 linkage groups using a previously published high-density linkage map. We performed
    coverage and FST analyses using male and female genomic and transcriptomic reads
    to quantify the extent of differentiation between the Z and W chromosomes. Additionally,
    we quantified the expression levels in male and female heads and gonads and found
    further evidence for dosage compensation in this species.
article_processing_charge: No
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
citation:
  ama: Elkrewi MN. Data from “Chromosome-level assembly of Artemia franciscana sheds
    light on sex-chromosome differentiation.” 2024. doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>
  apa: Elkrewi, M. N. (2024). Data from “Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.” Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>
  chicago: Elkrewi, Marwan N. “Data from ‘Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.’” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>.
  ieee: M. N. Elkrewi, “Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.’” Institute of Science and Technology
    Austria, 2024.
  ista: Elkrewi MN. 2024. Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation’, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  mla: Elkrewi, Marwan N. <i>Data from “Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.”</i> Institute of Science and Technology
    Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  short: M.N. Elkrewi, (2024).
contributor:
- contributor_type: researcher
  first_name: Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- contributor_type: project_member
  first_name: Ariana
  id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
  last_name: Macon
- contributor_type: supervisor
  first_name: Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- contributor_type: researcher
  first_name: Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
corr_author: '1'
date_created: 2023-12-22T13:40:48Z
date_published: 2024-01-02T00:00:00Z
date_updated: 2025-09-04T12:05:42Z
day: '02'
ddc:
- '576'
department:
- _id: GradSch
- _id: BeVi
doi: 10.15479/AT:ISTA:14705
file:
- access_level: open_access
  checksum: bdaf1392867786634ec5466d528c36ca
  content_type: text/plain
  creator: melkrewi
  date_created: 2023-12-22T13:54:21Z
  date_updated: 2023-12-22T13:54:21Z
  file_id: '14707'
  file_name: readme.txt.txt
  file_size: 847
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 973e1cbdab923a71709782177980829f
  content_type: application/x-zip-compressed
  creator: melkrewi
  date_created: 2023-12-22T14:14:06Z
  date_updated: 2023-12-22T14:14:06Z
  file_id: '14708'
  file_name: data_artemia_franciscana_genome.zip
  file_size: 343632753
  relation: main_file
  success: 1
file_date_updated: 2023-12-22T14:14:06Z
has_accepted_license: '1'
keyword:
- sex chromosome evolution
- genome assembly
- dosage compensation
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '15009'
    relation: used_in_publication
    status: public
status: public
title: Data from "Chromosome-level assembly of Artemia franciscana sheds light on
  sex-chromosome differentiation"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
OA_place: publisher
_id: '14711'
abstract:
- lang: eng
  text: "In nature, different species find their niche in a range of environments,
    each with its unique characteristics. While some thrive in uniform (homogeneous)
    landscapes where environmental conditions stay relatively consistent across space,
    others traverse the complexities of spatially heterogeneous terrains. Comprehending
    how species are distributed and how they interact within these landscapes holds
    the key to gaining insights into their evolutionary dynamics while also informing
    conservation and management strategies.\r\n\r\nFor species inhabiting heterogeneous
    landscapes, when the rate of dispersal is low compared to spatial fluctuations
    in selection pressure, localized adaptations may emerge. Such adaptation in response
    to varying selection strengths plays an important role in the persistence of populations
    in our rapidly changing world. Hence, species in nature are continuously in a
    struggle to adapt to local environmental conditions, to ensure their continued
    survival. Natural populations can often adapt in time scales short enough for
    evolutionary changes to influence ecological dynamics and vice versa, thereby
    creating a feedback between evolution and demography. The analysis of this feedback
    and the relative contributions of gene flow, demography, drift, and natural selection
    to genetic variation and differentiation has remained a recurring theme in evolutionary
    biology. Nevertheless, the effective role of these forces in maintaining variation
    and shaping patterns of diversity is not fully understood. Even in homogeneous
    environments devoid of local adaptations, such understanding remains elusive.
    Understanding this feedback is crucial, for example in determining the conditions
    under which extinction risk can be mitigated in peripheral populations subject
    to deleterious mutation accumulation at the edges of species’ ranges\r\nas well
    as in highly fragmented populations.\r\n\r\nIn this thesis we explore both uniform
    and spatially heterogeneous metapopulations, investigating and providing theoretical
    insights into the dynamics of local adaptation in the latter and examining the
    dynamics of load and extinction as well as the impact of joint ecological and
    evolutionary (eco-evolutionary) dynamics in the former. The thesis is divided
    into 5 chapters.\r\n\r\nChapter 1 provides a general introduction into the subject
    matter, clarifying concepts and ideas used throughout the thesis. In chapter 2,
    we explore how fast a species distributed across a heterogeneous landscape adapts
    to changing conditions marked by alterations in carrying capacity, selection pressure,
    and migration rate.\r\n\r\nIn chapter 3, we investigate how migration selection
    and drift influences adaptation and the maintenance of variation in a metapopulation
    with three habitats, an extension of previous models of adaptation in two habitats.
    We further develop analytical approximations for the critical threshold required
    for polymorphism to persist.\r\n\r\nThe focus of chapter 4 of the thesis is on
    understanding the interplay between ecology and evolution as coupled processes.
    We investigate how eco-evolutionary feedback between migration, selection, drift,
    and demography influences eco-evolutionary outcomes in marginal populations subject
    to deleterious mutation accumulation. Using simulations as well as theoretical
    approximations of the coupled dynamics of population size and allele frequency,
    we analyze how gene flow from a large mainland source influences genetic load
    and population size on an island (i.e., in a marginal population) under genetically
    realistic assumptions. Analyses of this sort are important because small isolated
    populations, are repeatedly affected by complex interactions between ecological
    and evolutionary processes, which can lead to their death. Understanding these
    interactions can therefore provide an insight into the conditions under which
    extinction risk can be mitigated in peripheral populations thus, contributing
    to conservation and restoration efforts.\r\n\r\nChapter 5 extends the analysis
    in chapter 4 to consider the dynamics of load (due to deleterious mutation accumulation)
    and extinction risk in a metapopulation. We explore the role of gene flow, selection,
    and dominance on load and extinction risk and further pinpoint critical thresholds
    required for metapopulation persistence.\r\n\r\nOverall this research contributes
    to our understanding of ecological and evolutionary mechanisms that shape species’
    persistence in fragmented landscapes, a crucial foundation for successful conservation
    efforts and biodiversity management."
acknowledged_ssus:
- _id: SSU
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
citation:
  ama: Olusanya OO. Local adaptation, genetic load and extinction in metapopulations.
    2024. doi:<a href="https://doi.org/10.15479/at:ista:14711">10.15479/at:ista:14711</a>
  apa: Olusanya, O. O. (2024). <i>Local adaptation, genetic load and extinction in
    metapopulations</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:14711">https://doi.org/10.15479/at:ista:14711</a>
  chicago: Olusanya, Oluwafunmilola O. “Local Adaptation, Genetic Load and Extinction
    in Metapopulations.” Institute of Science and Technology Austria, 2024. <a href="https://doi.org/10.15479/at:ista:14711">https://doi.org/10.15479/at:ista:14711</a>.
  ieee: O. O. Olusanya, “Local adaptation, genetic load and extinction in metapopulations,”
    Institute of Science and Technology Austria, 2024.
  ista: Olusanya OO. 2024. Local adaptation, genetic load and extinction in metapopulations.
    Institute of Science and Technology Austria.
  mla: Olusanya, Oluwafunmilola O. <i>Local Adaptation, Genetic Load and Extinction
    in Metapopulations</i>. Institute of Science and Technology Austria, 2024, doi:<a
    href="https://doi.org/10.15479/at:ista:14711">10.15479/at:ista:14711</a>.
  short: O.O. Olusanya, Local Adaptation, Genetic Load and Extinction in Metapopulations,
    Institute of Science and Technology Austria, 2024.
corr_author: '1'
date_created: 2023-12-26T22:49:53Z
date_published: 2024-01-19T00:00:00Z
date_updated: 2026-04-07T12:54:29Z
day: '19'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: NiBa
- _id: GradSch
doi: 10.15479/at:ista:14711
ec_funded: 1
file:
- access_level: closed
  checksum: de179b1c6758f182ff0c70d8b38c1501
  content_type: application/zip
  creator: oolusany
  date_created: 2024-01-03T18:30:13Z
  date_updated: 2024-01-03T18:30:13Z
  file_id: '14730'
  file_name: FinalSubmission_Thesis_OLUSANYA.zip
  file_size: 16986244
  relation: source_file
- access_level: open_access
  checksum: 0e331585e3cd4823320aab4e69e64ccf
  content_type: application/pdf
  creator: oolusany
  date_created: 2024-01-03T18:31:34Z
  date_updated: 2024-01-03T18:31:34Z
  file_id: '14731'
  file_name: FinalSubmission2_Thesis_OLUSANYA.pdf
  file_size: 6460403
  relation: main_file
  success: 1
file_date_updated: 2024-01-03T18:31:34Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '183'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
- _id: 34c872fe-11ca-11ed-8bc3-8534b82131e6
  grant_number: '26380'
  name: Polygenic Adaptation in a Metapopulation
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '10787'
    relation: part_of_dissertation
    status: public
  - id: '10658'
    relation: part_of_dissertation
    status: public
  - id: '14732'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jitka
  full_name: Polechova, Jitka
  last_name: Polechova
- first_name: Himani
  full_name: Sachdeva, Himani
  last_name: Sachdeva
title: Local adaptation, genetic load and extinction in metapopulations
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2024'
...
---
_id: '14726'
abstract:
- lang: eng
  text: Autocrine signaling pathways regulated by RAPID ALKALINIZATION FACTORs (RALFs)
    control cell wall integrity during pollen tube germination and growth in Arabidopsis
    (Arabidopsis thaliana). To investigate the role of pollen-specific RALFs in another
    plant species, we combined gene expression data with phylogenetic and biochemical
    studies to identify candidate orthologs in maize (Zea mays). We show that Clade
    IB ZmRALF2/3 mutations, but not Clade III ZmRALF1/5 mutations, cause cell wall
    instability in the sub-apical region of the growing pollen tube. ZmRALF2/3 are
    mainly located in the cell wall and are partially able to complement the pollen
    germination defect of their Arabidopsis orthologs AtRALF4/19. Mutations in ZmRALF2/3
    compromise pectin distribution patterns leading to altered cell wall organization
    and thickness culminating in pollen tube burst. Clade IB, but not Clade III ZmRALFs,
    strongly interact as ligands with the pollen-specific Catharanthus roseus RLK1-like
    (CrRLK1L) receptor kinases Zea mays FERONIA-like (ZmFERL) 4/7/9, LORELEI-like
    glycosylphosphatidylinositol-anchor (LLG) proteins Zea mays LLG 1 and 2 (ZmLLG1/2)
    and Zea mays pollen extension-like (PEX) cell wall proteins ZmPEX2/4. Notably,
    ZmFERL4 outcompetes ZmLLG2 and ZmPEX2 outcompetes ZmFERL4 for ZmRALF2 binding.
    Based on these data, we suggest that Clade IB RALFs act in a dual role as cell
    wall components and extracellular sensors to regulate cell wall integrity and
    thickness during pollen tube growth in maize and probably other plants.
article_number: koad324
article_processing_charge: No
article_type: original
author:
- first_name: Liang-Zi
  full_name: Zhou, Liang-Zi
  last_name: Zhou
- first_name: Lele
  full_name: Wang, Lele
  last_name: Wang
- first_name: Xia
  full_name: Chen, Xia
  last_name: Chen
- first_name: Zengxiang
  full_name: Ge, Zengxiang
  id: f43371a3-09ff-11eb-8013-bd0c6a2f6de8
  last_name: Ge
  orcid: 0000-0001-9381-3577
- first_name: Julia
  full_name: Mergner, Julia
  last_name: Mergner
- first_name: Xingli
  full_name: Li, Xingli
  last_name: Li
- first_name: Bernhard
  full_name: Küster, Bernhard
  last_name: Küster
- first_name: Gernot
  full_name: Längst, Gernot
  last_name: Längst
- first_name: Li-Jia
  full_name: Qu, Li-Jia
  last_name: Qu
- first_name: Thomas
  full_name: Dresselhaus, Thomas
  last_name: Dresselhaus
citation:
  ama: Zhou L-Z, Wang L, Chen X, et al. The RALF signaling pathway regulates cell
    wall integrity during pollen tube growth in maize. <i>The Plant Cell</i>. 2024;36(5).
    doi:<a href="https://doi.org/10.1093/plcell/koad324">10.1093/plcell/koad324</a>
  apa: Zhou, L.-Z., Wang, L., Chen, X., Ge, Z., Mergner, J., Li, X., … Dresselhaus,
    T. (2024). The RALF signaling pathway regulates cell wall integrity during pollen
    tube growth in maize. <i>The Plant Cell</i>. Oxford University Press. <a href="https://doi.org/10.1093/plcell/koad324">https://doi.org/10.1093/plcell/koad324</a>
  chicago: Zhou, Liang-Zi, Lele Wang, Xia Chen, Zengxiang Ge, Julia Mergner, Xingli
    Li, Bernhard Küster, Gernot Längst, Li-Jia Qu, and Thomas Dresselhaus. “The RALF
    Signaling Pathway Regulates Cell Wall Integrity during Pollen Tube Growth in Maize.”
    <i>The Plant Cell</i>. Oxford University Press, 2024. <a href="https://doi.org/10.1093/plcell/koad324">https://doi.org/10.1093/plcell/koad324</a>.
  ieee: L.-Z. Zhou <i>et al.</i>, “The RALF signaling pathway regulates cell wall
    integrity during pollen tube growth in maize,” <i>The Plant Cell</i>, vol. 36,
    no. 5. Oxford University Press, 2024.
  ista: Zhou L-Z, Wang L, Chen X, Ge Z, Mergner J, Li X, Küster B, Längst G, Qu L-J,
    Dresselhaus T. 2024. The RALF signaling pathway regulates cell wall integrity
    during pollen tube growth in maize. The Plant Cell. 36(5), koad324.
  mla: Zhou, Liang-Zi, et al. “The RALF Signaling Pathway Regulates Cell Wall Integrity
    during Pollen Tube Growth in Maize.” <i>The Plant Cell</i>, vol. 36, no. 5, koad324,
    Oxford University Press, 2024, doi:<a href="https://doi.org/10.1093/plcell/koad324">10.1093/plcell/koad324</a>.
  short: L.-Z. Zhou, L. Wang, X. Chen, Z. Ge, J. Mergner, X. Li, B. Küster, G. Längst,
    L.-J. Qu, T. Dresselhaus, The Plant Cell 36 (2024).
date_created: 2024-01-02T11:19:37Z
date_published: 2024-05-01T00:00:00Z
date_updated: 2024-07-16T11:18:46Z
day: '01'
ddc:
- '580'
doi: 10.1093/plcell/koad324
extern: '1'
external_id:
  pmid:
  - '38142229'
has_accepted_license: '1'
intvolume: '        36'
issue: '5'
keyword:
- Cell Biology
- Plant Science
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/plcell/koad324
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: The Plant Cell
publication_identifier:
  eissn:
  - 1532-298X
  issn:
  - 1040-4651
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The RALF signaling pathway regulates cell wall integrity during pollen tube
  growth in maize
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2024'
...
---
_id: '14733'
abstract:
- lang: eng
  text: Redox flow batteries (RFBs) rely on the development of cheap, highly soluble,
    and high-energy-density electrolytes. Several candidate quinones have already
    been investigated in the literature as two-electron anolytes or catholytes, benefiting
    from fast kinetics, high tunability, and low cost. Here, an investigation of nitrogen-rich
    fused heteroaromatic quinones was carried out to explore avenues for electrolyte
    development. These quinones were synthesized and screened by using electrochemical
    techniques. The most promising candidate, 4,8-dioxo-4,8-dihydrobenzo[1,2-d:4,5-d′]bis([1,2,3]triazole)-1,5-diide
    (−0.68 V(SHE)), was tested in both an asymmetric and symmetric full-cell setup
    resulting in capacity fade rates of 0.35% per cycle and 0.0124% per cycle, respectively.
    In situ ultraviolet-visible spectroscopy (UV–Vis), nuclear magnetic resonance
    (NMR), and electron paramagnetic resonance (EPR) spectroscopies were used to investigate
    the electrochemical stability of the charged species during operation. UV–Vis
    spectroscopy, supported by density functional theory (DFT) modeling, reaffirmed
    that the two-step charging mechanism observed during battery operation consisted
    of two, single-electron transfers. The radical concentration during battery operation
    and the degree of delocalization of the unpaired electron were quantified with
    NMR and EPR spectroscopy.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Rajesh B
  full_name: Jethwa, Rajesh B
  id: 4cc538d5-803f-11ed-ab7e-8139573aad8f
  last_name: Jethwa
  orcid: 0000-0002-0404-4356
- first_name: Dominic
  full_name: Hey, Dominic
  last_name: Hey
- first_name: Rachel N.
  full_name: Kerber, Rachel N.
  last_name: Kerber
- first_name: Andrew D.
  full_name: Bond, Andrew D.
  last_name: Bond
- first_name: Dominic S.
  full_name: Wright, Dominic S.
  last_name: Wright
- first_name: Clare P.
  full_name: Grey, Clare P.
  last_name: Grey
citation:
  ama: Jethwa RB, Hey D, Kerber RN, Bond AD, Wright DS, Grey CP. Exploring the landscape
    of heterocyclic quinones for redox flow batteries. <i>ACS Applied Energy Materials</i>.
    2024;7(2):414-426. doi:<a href="https://doi.org/10.1021/acsaem.3c02223">10.1021/acsaem.3c02223</a>
  apa: Jethwa, R. B., Hey, D., Kerber, R. N., Bond, A. D., Wright, D. S., &#38; Grey,
    C. P. (2024). Exploring the landscape of heterocyclic quinones for redox flow
    batteries. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a
    href="https://doi.org/10.1021/acsaem.3c02223">https://doi.org/10.1021/acsaem.3c02223</a>
  chicago: Jethwa, Rajesh B, Dominic Hey, Rachel N. Kerber, Andrew D. Bond, Dominic
    S. Wright, and Clare P. Grey. “Exploring the Landscape of Heterocyclic Quinones
    for Redox Flow Batteries.” <i>ACS Applied Energy Materials</i>. American Chemical
    Society, 2024. <a href="https://doi.org/10.1021/acsaem.3c02223">https://doi.org/10.1021/acsaem.3c02223</a>.
  ieee: R. B. Jethwa, D. Hey, R. N. Kerber, A. D. Bond, D. S. Wright, and C. P. Grey,
    “Exploring the landscape of heterocyclic quinones for redox flow batteries,” <i>ACS
    Applied Energy Materials</i>, vol. 7, no. 2. American Chemical Society, pp. 414–426,
    2024.
  ista: Jethwa RB, Hey D, Kerber RN, Bond AD, Wright DS, Grey CP. 2024. Exploring
    the landscape of heterocyclic quinones for redox flow batteries. ACS Applied Energy
    Materials. 7(2), 414–426.
  mla: Jethwa, Rajesh B., et al. “Exploring the Landscape of Heterocyclic Quinones
    for Redox Flow Batteries.” <i>ACS Applied Energy Materials</i>, vol. 7, no. 2,
    American Chemical Society, 2024, pp. 414–26, doi:<a href="https://doi.org/10.1021/acsaem.3c02223">10.1021/acsaem.3c02223</a>.
  short: R.B. Jethwa, D. Hey, R.N. Kerber, A.D. Bond, D.S. Wright, C.P. Grey, ACS
    Applied Energy Materials 7 (2024) 414–426.
date_created: 2024-01-05T09:20:48Z
date_published: 2024-01-22T00:00:00Z
date_updated: 2025-09-04T11:36:32Z
day: '22'
ddc:
- '540'
department:
- _id: StFr
doi: 10.1021/acsaem.3c02223
ec_funded: 1
external_id:
  isi:
  - '001146733200001'
  pmid:
  - '38273966'
file:
- access_level: open_access
  checksum: 2841e86a041d249ac0df2531b7f9aec1
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-16T11:59:24Z
  date_updated: 2024-07-16T11:59:24Z
  file_id: '17262'
  file_name: 2024_ACSAppElecMaterials_Jethwa.pdf
  file_size: 5607177
  relation: main_file
  success: 1
file_date_updated: 2024-07-16T11:59:24Z
has_accepted_license: '1'
intvolume: '         7'
isi: 1
issue: '2'
keyword:
- Electrical and Electronic Engineering
- Materials Chemistry
- Electrochemistry
- Energy Engineering and Power Technology
- Chemical Engineering (miscellaneous)
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1021/acsaem.3c02223
month: '01'
oa: 1
oa_version: Published Version
page: 414-426
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: ACS Applied Energy Materials
publication_identifier:
  eissn:
  - 2574-0962
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exploring the landscape of heterocyclic quinones for redox flow batteries
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 7
year: '2024'
...
---
OA_type: closed access
_id: '14734'
abstract:
- lang: eng
  text: Developing cost-effective and high-performance thermoelectric (TE) materials
    to assemble efficient TE devices presents a multitude of challenges and opportunities.
    Cu3SbSe4 is a promising p-type TE material based on relatively earth abundant
    elements. However, the challenge lies in its poor electrical conductivity. Herein,
    an efficient and scalable solution-based approach is developed to synthesize high-quality
    Cu3SbSe4 nanocrystals doped with Pb at the Sb site. After ligand displacement
    and annealing treatments, the dried powders are consolidated into dense pellets,
    and their TE properties are investigated. Pb doping effectively increases the
    charge carrier concentration, resulting in a significant increase in electrical
    conductivity, while the Seebeck coefficients remain consistently high. The calculated
    band structure shows that Pb doping induces band convergence, thereby increasing
    the effective mass. Furthermore, the large ionic radius of Pb2+ results in the
    generation of additional point and plane defects and interphases, dramatically
    enhancing phonon scattering, which significantly decreases the lattice thermal
    conductivity at high temperatures. Overall, a maximum figure of merit (zTmax)
    ≈ 0.85 at 653 K is obtained in Cu3Sb0.97Pb0.03Se4. This represents a 1.6-fold
    increase compared to the undoped sample and exceeds most doped Cu3SbSe4-based
    materials produced by solid-state, demonstrating advantages of versatility and
    cost-effectiveness using a solution-based technology.
acknowledgement: Y.L. acknowledges funding from the National Natural Science Foundation
  of China (NSFC) (Grants No. 22209034), the Innovation and Entrepreneurship Project
  of Overseas Returnees in Anhui Province (Grant No. 2022LCX002). K.H.L. acknowledges
  financial support from the National Natural Science Foundation of China (NSFC) (Grant
  No. 22208293). M.I. acknowledges financial support from ISTA and the Werner Siemens
  Foundation.
article_number: '2301377'
article_processing_charge: No
article_type: original
author:
- first_name: Shanhong
  full_name: Wan, Shanhong
  last_name: Wan
- first_name: Shanshan
  full_name: Xiao, Shanshan
  last_name: Xiao
- first_name: Mingquan
  full_name: Li, Mingquan
  last_name: Li
- first_name: Xin
  full_name: Wang, Xin
  last_name: Wang
- first_name: Khak Ho
  full_name: Lim, Khak Ho
  last_name: Lim
- first_name: Min
  full_name: Hong, Min
  last_name: Hong
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Andreu
  full_name: Cabot, Andreu
  last_name: Cabot
- first_name: Yu
  full_name: Liu, Yu
  id: 2A70014E-F248-11E8-B48F-1D18A9856A87
  last_name: Liu
  orcid: 0000-0001-7313-6740
citation:
  ama: Wan S, Xiao S, Li M, et al. Band engineering through Pb-doping of nanocrystal
    building blocks to enhance thermoelectric performance in Cu3SbSe4. <i>Small Methods</i>.
    2024;8(8). doi:<a href="https://doi.org/10.1002/smtd.202301377">10.1002/smtd.202301377</a>
  apa: Wan, S., Xiao, S., Li, M., Wang, X., Lim, K. H., Hong, M., … Liu, Y. (2024).
    Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric
    performance in Cu3SbSe4. <i>Small Methods</i>. Wiley. <a href="https://doi.org/10.1002/smtd.202301377">https://doi.org/10.1002/smtd.202301377</a>
  chicago: Wan, Shanhong, Shanshan Xiao, Mingquan Li, Xin Wang, Khak Ho Lim, Min Hong,
    Maria Ibáñez, Andreu Cabot, and Yu Liu. “Band Engineering through Pb-Doping of
    Nanocrystal Building Blocks to Enhance Thermoelectric Performance in Cu3SbSe4.”
    <i>Small Methods</i>. Wiley, 2024. <a href="https://doi.org/10.1002/smtd.202301377">https://doi.org/10.1002/smtd.202301377</a>.
  ieee: S. Wan <i>et al.</i>, “Band engineering through Pb-doping of nanocrystal building
    blocks to enhance thermoelectric performance in Cu3SbSe4,” <i>Small Methods</i>,
    vol. 8, no. 8. Wiley, 2024.
  ista: Wan S, Xiao S, Li M, Wang X, Lim KH, Hong M, Ibáñez M, Cabot A, Liu Y. 2024.
    Band engineering through Pb-doping of nanocrystal building blocks to enhance thermoelectric
    performance in Cu3SbSe4. Small Methods. 8(8), 2301377.
  mla: Wan, Shanhong, et al. “Band Engineering through Pb-Doping of Nanocrystal Building
    Blocks to Enhance Thermoelectric Performance in Cu3SbSe4.” <i>Small Methods</i>,
    vol. 8, no. 8, 2301377, Wiley, 2024, doi:<a href="https://doi.org/10.1002/smtd.202301377">10.1002/smtd.202301377</a>.
  short: S. Wan, S. Xiao, M. Li, X. Wang, K.H. Lim, M. Hong, M. Ibáñez, A. Cabot,
    Y. Liu, Small Methods 8 (2024).
date_created: 2024-01-07T23:00:51Z
date_published: 2024-08-01T00:00:00Z
date_updated: 2025-09-04T11:37:19Z
day: '01'
department:
- _id: MaIb
doi: 10.1002/smtd.202301377
external_id:
  isi:
  - '001133369800001'
  pmid:
  - '38152986'
intvolume: '         8'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
pmid: 1
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: Small Methods
publication_identifier:
  eissn:
  - 2366-9608
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Band engineering through Pb-doping of nanocrystal building blocks to enhance
  thermoelectric performance in Cu3SbSe4
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2024'
...
---
_id: '14769'
abstract:
- lang: eng
  text: 'For a set of points in Rd, the Euclidean k-means problems consists of finding
    k centers such that the sum of distances squared from each data point to its closest
    center is minimized. Coresets are one the main tools developed recently to solve
    this problem in a big data context. They allow to compress the initial dataset
    while preserving its structure: running any algorithm on the coreset provides
    a guarantee almost equivalent to running it on the full data. In this work, we
    study coresets in a fully-dynamic setting: points are added and deleted with the
    goal to efficiently maintain a coreset with which a k-means solution can be computed.
    Based on an algorithm from Henzinger and Kale [ESA''20], we present an efficient
    and practical implementation of a fully dynamic coreset algorithm, that improves
    the running time by up to a factor of 20 compared to our non-optimized implementation
    of the algorithm by Henzinger and Kale, without sacrificing more than 7% on the
    quality of the k-means solution.'
acknowledgement: This   project   has   received   funding   from   the   Euro-pean  Research  Council  (ERC)  under  the  EuropeanUnion’s  Horizon  2020  research  and  innovation  programme  (Grant  agreement  No.   101019564  “The  De-sign  of  Modern  Fully  Dynamic  Data  Structures  (Mo-DynStruct)”  and  the  Austrian  Science  Fund  (FWF)project
  Z 422-N, project “Static and Dynamic Hierar-chical  Graph  Decompositions”,  I  5982-N,  and  project“Fast  Algorithms  for  a  Reactive  Network  Layer  (Re-actNet)”,
  P 33775-N, with additional funding from thenetidee SCIENCE Stiftung, 2020–2024.D.  Sauplic  has  received  funding  from  the  Euro-pean  Union’s  Horizon  2020  research  and  innovation
  programme under the Marie Sklodowska-Curie    grant    agreementNo 101034413.
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: David
  full_name: Saulpic, David
  id: f8e48cf0-b0ff-11ed-b0e9-b4c35598f964
  last_name: Saulpic
- first_name: Leonhard
  full_name: Sidl, Leonhard
  id: 8b563fd0-b441-11ee-9101-a3891c61efa6
  last_name: Sidl
citation:
  ama: 'Henzinger M, Saulpic D, Sidl L. Experimental evaluation of fully dynamic k-means
    via coresets. In: <i>2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments</i>. Society for Industrial and Applied Mathematics; 2024:220-233.
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>'
  apa: 'Henzinger, M., Saulpic, D., &#38; Sidl, L. (2024). Experimental evaluation
    of fully dynamic k-means via coresets. In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i> (pp. 220–233). Alexandria, VA, United
    States: Society for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>'
  chicago: Henzinger, Monika, David Saulpic, and Leonhard Sidl. “Experimental Evaluation
    of Fully Dynamic K-Means via Coresets.” In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i>, 220–33. Society for Industrial and
    Applied Mathematics, 2024. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>.
  ieee: M. Henzinger, D. Saulpic, and L. Sidl, “Experimental evaluation of fully dynamic
    k-means via coresets,” in <i>2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments</i>, Alexandria, VA, United States, 2024, pp. 220–233.
  ista: 'Henzinger M, Saulpic D, Sidl L. 2024. Experimental evaluation of fully dynamic
    k-means via coresets. 2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments. ALENEX: Workshop on Algorithm Engineering and Experiments, 220–233.'
  mla: Henzinger, Monika, et al. “Experimental Evaluation of Fully Dynamic K-Means
    via Coresets.” <i>2024 Proceedings of the Symposium on Algorithm Engineering and
    Experiments</i>, Society for Industrial and Applied Mathematics, 2024, pp. 220–33,
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>.
  short: M. Henzinger, D. Saulpic, L. Sidl, in:, 2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments, Society for Industrial and Applied Mathematics,
    2024, pp. 220–233.
conference:
  end_date: 2024-01-08
  location: Alexandria, VA, United States
  name: 'ALENEX: Workshop on Algorithm Engineering and Experiments'
  start_date: 2024-01-07
corr_author: '1'
date_created: 2024-01-09T16:22:47Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-04-14T13:50:50Z
day: '04'
department:
- _id: MoHe
doi: 10.1137/1.9781611977929.17
ec_funded: 1
external_id:
  arxiv:
  - '2310.18034'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2310.18034
month: '01'
oa: 1
oa_version: Preprint
page: 220-233
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
  grant_number: Z00422
  name: Efficient algorithms
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
  grant_number: I05982
  name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
  grant_number: P33775
  name: Fast Algorithms for a Reactive Network Layer
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments
publication_identifier:
  eisbn:
  - '9781611977929'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental evaluation of fully dynamic k-means via coresets
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
APC_amount: 6468 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '14793'
abstract:
- lang: eng
  text: Superconductor/semiconductor hybrid devices have attracted increasing interest
    in the past years. Superconducting electronics aims to complement semiconductor
    technology, while hybrid architectures are at the forefront of new ideas such
    as topological superconductivity and protected qubits. In this work, we engineer
    the induced superconductivity in two-dimensional germanium hole gas by varying
    the distance between the quantum well and the aluminum. We demonstrate a hard
    superconducting gap and realize an electrically and flux tunable superconducting
    diode using a superconducting quantum interference device (SQUID). This allows
    to tune the current phase relation (CPR), to a regime where single Cooper pair
    tunneling is suppressed, creating a sin(2y) CPR. Shapiro experiments complement
    this interpretation and the microwave drive allows to create a diode with ≈ 100%
    efficiency. The reported results open up the path towards integration of spin
    qubit devices, microwave resonators and (protected) superconducting qubits on  the
    same silicon technology compatible platform.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
acknowledgement: "We acknowledge Alexander Brinkmann, Alessandro Crippa, Francesco
  Giazotto, Andrew Higginbotham, Andrea Iorio, Giordano Scappucci, Christian Schonenberger,
  and Lukas Splitthoff for helpful discussions. We thank Marcel Verheijen for the
  support in the TEM analysis. This research and related results were made possible
  with the support of the NOMIS\r\nFoundation. It was supported by the Scientific
  Service Units of ISTA through resources provided by the MIBA Machine Shop and the
  nanofabrication facility, the European Union’s Horizon 2020 research andinnovation
  programme under Grant Agreement No 862046, the HORIZONRIA\r\n101069515 project,
  the European Innovation Council Pathfinder grant no. 101115315 (QuKiT), and the
  FWF Projects #P-32235, #P-36507 and #F-8606. For the purpose of open access, the
  authors have applied a CC BY public copyright licence to any Author Accepted Manuscript
  version arising from this submission. R.S.S. acknowledges Spanish CM “Talento Program\"\r\nProject
  No. 2022-T1/IND-24070. J.J. acknowledges European Research Council TOCINA 834290."
article_number: '169'
article_processing_charge: Yes
article_type: original
author:
- first_name: Marco
  full_name: Valentini, Marco
  id: C0BB2FAC-D767-11E9-B658-BC13E6697425
  last_name: Valentini
- first_name: Oliver
  full_name: Sagi, Oliver
  id: 71616374-A8E9-11E9-A7CA-09ECE5697425
  last_name: Sagi
- first_name: Levon
  full_name: Baghumyan, Levon
  id: 7aa1f788-b527-11ee-aa9e-e6111a79e0c7
  last_name: Baghumyan
- first_name: Thijs
  full_name: de Gijsel, Thijs
  id: a0ece13c-b527-11ee-929d-bad130106eee
  last_name: de Gijsel
- first_name: Jason
  full_name: Jung, Jason
  id: 4C9ACE7A-F248-11E8-B48F-1D18A9856A87
  last_name: Jung
- first_name: Stefano
  full_name: Calcaterra, Stefano
  last_name: Calcaterra
- first_name: Andrea
  full_name: Ballabio, Andrea
  last_name: Ballabio
- first_name: Juan L
  full_name: Aguilera Servin, Juan L
  id: 2A67C376-F248-11E8-B48F-1D18A9856A87
  last_name: Aguilera Servin
  orcid: 0000-0002-2862-8372
- first_name: Kushagra
  full_name: Aggarwal, Kushagra
  id: b22ab905-3539-11eb-84c3-fc159dcd79cb
  last_name: Aggarwal
  orcid: 0000-0001-9985-9293
- first_name: Marian
  full_name: Janik, Marian
  id: 396A1950-F248-11E8-B48F-1D18A9856A87
  last_name: Janik
  orcid: 0009-0003-9037-8831
- first_name: Thomas
  full_name: Adletzberger, Thomas
  id: 38756BB2-F248-11E8-B48F-1D18A9856A87
  last_name: Adletzberger
- first_name: Rubén
  full_name: Seoane Souto, Rubén
  last_name: Seoane Souto
- first_name: Martin
  full_name: Leijnse, Martin
  last_name: Leijnse
- first_name: Jeroen
  full_name: Danon, Jeroen
  last_name: Danon
- first_name: Constantin
  full_name: Schrade, Constantin
  last_name: Schrade
- first_name: Erik
  full_name: Bakkers, Erik
  last_name: Bakkers
- first_name: Daniel
  full_name: Chrastina, Daniel
  last_name: Chrastina
- first_name: Giovanni
  full_name: Isella, Giovanni
  last_name: Isella
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Valentini M, Sagi O, Baghumyan L, et al. Parity-conserving Cooper-pair transport
    and ideal superconducting diode in planar germanium. <i>Nature Communications</i>.
    2024;15. doi:<a href="https://doi.org/10.1038/s41467-023-44114-0">10.1038/s41467-023-44114-0</a>
  apa: Valentini, M., Sagi, O., Baghumyan, L., de Gijsel, T., Jung, J., Calcaterra,
    S., … Katsaros, G. (2024). Parity-conserving Cooper-pair transport and ideal superconducting
    diode in planar germanium. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-023-44114-0">https://doi.org/10.1038/s41467-023-44114-0</a>
  chicago: Valentini, Marco, Oliver Sagi, Levon Baghumyan, Thijs de Gijsel, Jason
    Jung, Stefano Calcaterra, Andrea Ballabio, et al. “Parity-Conserving Cooper-Pair
    Transport and Ideal Superconducting Diode in Planar Germanium.” <i>Nature Communications</i>.
    Springer Nature, 2024. <a href="https://doi.org/10.1038/s41467-023-44114-0">https://doi.org/10.1038/s41467-023-44114-0</a>.
  ieee: M. Valentini <i>et al.</i>, “Parity-conserving Cooper-pair transport and ideal
    superconducting diode in planar germanium,” <i>Nature Communications</i>, vol.
    15. Springer Nature, 2024.
  ista: Valentini M, Sagi O, Baghumyan L, de Gijsel T, Jung J, Calcaterra S, Ballabio
    A, Aguilera Servin JL, Aggarwal K, Janik M, Adletzberger T, Seoane Souto R, Leijnse
    M, Danon J, Schrade C, Bakkers E, Chrastina D, Isella G, Katsaros G. 2024. Parity-conserving
    Cooper-pair transport and ideal superconducting diode in planar germanium. Nature
    Communications. 15, 169.
  mla: Valentini, Marco, et al. “Parity-Conserving Cooper-Pair Transport and Ideal
    Superconducting Diode in Planar Germanium.” <i>Nature Communications</i>, vol.
    15, 169, Springer Nature, 2024, doi:<a href="https://doi.org/10.1038/s41467-023-44114-0">10.1038/s41467-023-44114-0</a>.
  short: M. Valentini, O. Sagi, L. Baghumyan, T. de Gijsel, J. Jung, S. Calcaterra,
    A. Ballabio, J.L. Aguilera Servin, K. Aggarwal, M. Janik, T. Adletzberger, R.
    Seoane Souto, M. Leijnse, J. Danon, C. Schrade, E. Bakkers, D. Chrastina, G. Isella,
    G. Katsaros, Nature Communications 15 (2024).
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-02T00:00:00Z
date_updated: 2025-10-15T06:31:47Z
day: '02'
ddc:
- '530'
department:
- _id: GeKa
doi: 10.1038/s41467-023-44114-0
ec_funded: 1
external_id:
  isi:
  - '001142794000839'
  pmid:
  - '38167818'
file:
- access_level: open_access
  checksum: ef79173b45eeaf984ffa61ef2f8a52ab
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-17T11:03:00Z
  date_updated: 2024-01-17T11:03:00Z
  file_id: '14825'
  file_name: 2024_NatureComm_Valentini.pdf
  file_size: 2336595
  relation: main_file
  success: 1
file_date_updated: 2024-01-17T11:03:00Z
has_accepted_license: '1'
intvolume: '        15'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
- _id: 34c0acea-11ca-11ed-8bc3-8775e10fd452
  grant_number: '101069515'
  name: Integrated Germanium Quantum Technology
- _id: bdc2ca30-d553-11ed-ba76-cf164a5bb811
  grant_number: '101115315'
  name: Quantum bits with Kitaev Transmons
- _id: 237B3DA4-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: P32235
  name: Towards scalable hut wire quantum devices
- _id: bd8bd29e-d553-11ed-ba76-f0070d4b237a
  grant_number: P36507
  name: Merging spin and superconducting qubits in planar Ge
- _id: 34a66131-11ca-11ed-8bc3-a31681c6b03e
  grant_number: F8606
  name: 'Center for Correlated Quantum Materials and Solid State Quantum Systems:
    Conventional  and unconventional topological superconductors'
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Parity-conserving Cooper-pair transport and ideal superconducting diode in
  planar germanium
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2024'
...
---
_id: '14794'
abstract:
- lang: eng
  text: "Mosaic analysis with double markers (MADM) technology enables the sparse
    labeling of genetically defined neurons. We present a protocol for time-lapse
    imaging of cortical projection neuron migration in mice using MADM. We describe
    steps for the isolation, culturing, and 4D imaging of neuronal dynamics in MADM-labeled
    brain tissue. While this protocol is compatible with other single-cell labeling
    methods, the MADM approach provides a genetic platform for the functional assessment
    of cell-autonomous candidate gene function and the relative contribution of non-cell-autonomous
    effects.\r\n\r\nFor complete details on the use and execution of this protocol,
    please refer to Hansen et al. (2022),1 Contreras et al. (2021),2 and Amberg and
    Hippenmeyer (2021).3"
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: We thank Florian Pauler for discussion and his expert technical support.
  This research was supported by the Scientific Service Units (SSU) at IST Austria
  through resources provided by the Imaging and Optics Facility (IOF) and Preclinical
  Facility (PCF). A.H.H. was a recipient of a DOC Fellowship (24812) of the Austrian
  Academy of Sciences.
article_number: '102795'
article_processing_charge: Yes
article_type: review
author:
- first_name: Andi H
  full_name: Hansen, Andi H
  id: 38853E16-F248-11E8-B48F-1D18A9856A87
  last_name: Hansen
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Hansen AH, Hippenmeyer S. Time-lapse imaging of cortical projection neuron
    migration in mice using mosaic analysis with double markers. <i>STAR Protocols</i>.
    2024;5(1). doi:<a href="https://doi.org/10.1016/j.xpro.2023.102795">10.1016/j.xpro.2023.102795</a>
  apa: Hansen, A. H., &#38; Hippenmeyer, S. (2024). Time-lapse imaging of cortical
    projection neuron migration in mice using mosaic analysis with double markers.
    <i>STAR Protocols</i>. Elsevier. <a href="https://doi.org/10.1016/j.xpro.2023.102795">https://doi.org/10.1016/j.xpro.2023.102795</a>
  chicago: Hansen, Andi H, and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical
    Projection Neuron Migration in Mice Using Mosaic Analysis with Double Markers.”
    <i>STAR Protocols</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.xpro.2023.102795">https://doi.org/10.1016/j.xpro.2023.102795</a>.
  ieee: A. H. Hansen and S. Hippenmeyer, “Time-lapse imaging of cortical projection
    neuron migration in mice using mosaic analysis with double markers,” <i>STAR Protocols</i>,
    vol. 5, no. 1. Elsevier, 2024.
  ista: Hansen AH, Hippenmeyer S. 2024. Time-lapse imaging of cortical projection
    neuron migration in mice using mosaic analysis with double markers. STAR Protocols.
    5(1), 102795.
  mla: Hansen, Andi H., and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical Projection
    Neuron Migration in Mice Using Mosaic Analysis with Double Markers.” <i>STAR Protocols</i>,
    vol. 5, no. 1, 102795, Elsevier, 2024, doi:<a href="https://doi.org/10.1016/j.xpro.2023.102795">10.1016/j.xpro.2023.102795</a>.
  short: A.H. Hansen, S. Hippenmeyer, STAR Protocols 5 (2024).
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-03-15T00:00:00Z
date_updated: 2025-04-15T07:32:40Z
day: '15'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.xpro.2023.102795
external_id:
  pmid:
  - '38165800'
file:
- access_level: open_access
  checksum: 4644d537451c5c114a9d7c7829b65bba
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-16T12:04:46Z
  date_updated: 2024-07-16T12:04:46Z
  file_id: '17264'
  file_name: 2024_STARProtoc_Hansen.pdf
  file_size: 3758943
  relation: main_file
  success: 1
file_date_updated: 2024-07-16T12:04:46Z
has_accepted_license: '1'
intvolume: '         5'
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2625A13E-B435-11E9-9278-68D0E5697425
  grant_number: '24812'
  name: Molecular mechanisms of radial neuronal migration
publication: STAR Protocols
publication_identifier:
  eissn:
  - 2666-1667
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: http://github.com/hippenmeyerlab
scopus_import: '1'
status: public
title: Time-lapse imaging of cortical projection neuron migration in mice using mosaic
  analysis with double markers
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
_id: '14795'
abstract:
- lang: eng
  text: Metazoan development relies on the formation and remodeling of cell-cell contacts.
    Dynamic reorganization of adhesion receptors and the actomyosin cell cortex in
    space and time plays a central role in cell-cell contact formation and maturation.
    Nevertheless, how this process is mechanistically achieved when new contacts are
    formed remains unclear. Here, by building a biomimetic assay composed of progenitor
    cells adhering to supported lipid bilayers functionalized with E-cadherin ectodomains,
    we show that cortical F-actin flows, driven by the depletion of myosin-2 at the
    cell contact center, mediate the dynamic reorganization of adhesion receptors
    and cell cortex at the contact. E-cadherin-dependent downregulation of the small
    GTPase RhoA at the forming contact leads to both a depletion of myosin-2 and a
    decrease of F-actin at the contact center. At the contact rim, in contrast, myosin-2
    becomes enriched by the retraction of bleb-like protrusions, resulting in a cortical
    tension gradient from the contact rim to its center. This tension gradient, in
    turn, triggers centrifugal F-actin flows, leading to further accumulation of F-actin
    at the contact rim and the progressive redistribution of E-cadherin from the contact
    center to the rim. Eventually, this combination of actomyosin downregulation and
    flows at the contact determines the characteristic molecular organization, with
    E-cadherin and F-actin accumulating at the contact rim, where they are needed
    to mechanically link the contractile cortices of the adhering cells.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
acknowledgement: "We are grateful to Edwin Munro for their feedback and help with
  the single particle analysis. We thank members of the Heisenberg and Loose labs
  for their help and feedback on the manuscript, notably Xin Tong for making the PCS2-mCherry-AHPH
  plasmid. Finally, we thank the Aquatics and Imaging & Optics facilities of ISTA
  for their continuous support, especially Yann Cesbron for assistance with the laser
  cutter. This work was supported by an ERC\r\nAdvanced Grant (MECSPEC) to C.-P.H."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Feyza N
  full_name: Arslan, Feyza N
  id: 49DA7910-F248-11E8-B48F-1D18A9856A87
  last_name: Arslan
  orcid: 0000-0001-5809-9566
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. Adhesion-induced
    cortical flows pattern E-cadherin-mediated cell contacts. <i>Current Biology</i>.
    2024;34(1):171-182.e8. doi:<a href="https://doi.org/10.1016/j.cub.2023.11.067">10.1016/j.cub.2023.11.067</a>
  apa: Arslan, F. N., Hannezo, E. B., Merrin, J., Loose, M., &#38; Heisenberg, C.-P.
    J. (2024). Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts.
    <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2023.11.067">https://doi.org/10.1016/j.cub.2023.11.067</a>
  chicago: Arslan, Feyza N, Edouard B Hannezo, Jack Merrin, Martin Loose, and Carl-Philipp
    J Heisenberg. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell
    Contacts.” <i>Current Biology</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.cub.2023.11.067">https://doi.org/10.1016/j.cub.2023.11.067</a>.
  ieee: F. N. Arslan, E. B. Hannezo, J. Merrin, M. Loose, and C.-P. J. Heisenberg,
    “Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts,” <i>Current
    Biology</i>, vol. 34, no. 1. Elsevier, p. 171–182.e8, 2024.
  ista: Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. 2024. Adhesion-induced
    cortical flows pattern E-cadherin-mediated cell contacts. Current Biology. 34(1),
    171–182.e8.
  mla: Arslan, Feyza N., et al. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated
    Cell Contacts.” <i>Current Biology</i>, vol. 34, no. 1, Elsevier, 2024, p. 171–182.e8,
    doi:<a href="https://doi.org/10.1016/j.cub.2023.11.067">10.1016/j.cub.2023.11.067</a>.
  short: F.N. Arslan, E.B. Hannezo, J. Merrin, M. Loose, C.-P.J. Heisenberg, Current
    Biology 34 (2024) 171–182.e8.
corr_author: '1'
date_created: 2024-01-14T23:00:56Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2025-09-04T11:39:10Z
day: '08'
ddc:
- '570'
department:
- _id: CaHe
- _id: EdHa
- _id: MaLo
- _id: NanoFab
doi: 10.1016/j.cub.2023.11.067
ec_funded: 1
external_id:
  isi:
  - '001154500400001'
  pmid:
  - '38134934'
file:
- access_level: open_access
  checksum: 51220b76d72a614208f84bdbfbaf9b72
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-16T10:53:31Z
  date_updated: 2024-01-16T10:53:31Z
  file_id: '14813'
  file_name: 2024_CurrentBiology_Arslan.pdf
  file_size: 5183861
  relation: main_file
  success: 1
file_date_updated: 2024-01-16T10:53:31Z
has_accepted_license: '1'
intvolume: '        34'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 171-182.e8
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742573'
  name: Interaction and feedback between cell mechanics and fate specification in
    vertebrate gastrulation
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 34
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14797'
abstract:
- lang: eng
  text: We study a random matching problem on closed compact  2 -dimensional Riemannian
    manifolds (with respect to the squared Riemannian distance), with samples of random
    points whose common law is absolutely continuous with respect to the volume measure
    with strictly positive and bounded density. We show that given two sequences of
    numbers  n  and  m=m(n)  of points, asymptotically equivalent as  n  goes to infinity,
    the optimal transport plan between the two empirical measures  μn  and  νm  is
    quantitatively well-approximated by  (Id,exp(∇hn))#μn  where  hn  solves a linear
    elliptic PDE obtained by a regularized first-order linearization of the Monge-Ampère
    equation. This is obtained in the case of samples of correlated random points
    for which a stretched exponential decay of the  α -mixing coefficient holds and
    for a class of discrete-time Markov chains having a unique absolutely continuous
    invariant measure with respect to the volume measure.
acknowledgement: "NC has received funding from the European Research Council (ERC)
  under the European Union’s Horizon 2020 research and innovation programme (Grant
  agreement No 948819).\r\nFM is supported by the Deutsche Forschungsgemeinschaft
  (DFG, German Research Foundation) through the SPP 2265 Random Geometric Systems.
  FM has been funded by the Deutsche Forschungsgemeinschaft (DFG, German Research
  Foundation) under Germany’s Excellence Strategy EXC 2044 -390685587, Mathematics
  Münster: Dynamics–Geometry–Structure. FM has been funded by the Max Planck Institute
  for Mathematics in the Sciences."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Nicolas
  full_name: Clozeau, Nicolas
  id: fea1b376-906f-11eb-847d-b2c0cf46455b
  last_name: Clozeau
- first_name: Francesco
  full_name: Mattesini, Francesco
  last_name: Mattesini
citation:
  ama: Clozeau N, Mattesini F. Annealed quantitative estimates for the quadratic 2D-discrete
    random matching problem. <i>Probability Theory and Related Fields</i>. 2024;190:485-541.
    doi:<a href="https://doi.org/10.1007/s00440-023-01254-0">10.1007/s00440-023-01254-0</a>
  apa: Clozeau, N., &#38; Mattesini, F. (2024). Annealed quantitative estimates for
    the quadratic 2D-discrete random matching problem. <i>Probability Theory and Related
    Fields</i>. Springer Nature. <a href="https://doi.org/10.1007/s00440-023-01254-0">https://doi.org/10.1007/s00440-023-01254-0</a>
  chicago: Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates
    for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory
    and Related Fields</i>. Springer Nature, 2024. <a href="https://doi.org/10.1007/s00440-023-01254-0">https://doi.org/10.1007/s00440-023-01254-0</a>.
  ieee: N. Clozeau and F. Mattesini, “Annealed quantitative estimates for the quadratic
    2D-discrete random matching problem,” <i>Probability Theory and Related Fields</i>,
    vol. 190. Springer Nature, pp. 485–541, 2024.
  ista: Clozeau N, Mattesini F. 2024. Annealed quantitative estimates for the quadratic
    2D-discrete random matching problem. Probability Theory and Related Fields. 190,
    485–541.
  mla: Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates
    for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory
    and Related Fields</i>, vol. 190, Springer Nature, 2024, pp. 485–541, doi:<a href="https://doi.org/10.1007/s00440-023-01254-0">10.1007/s00440-023-01254-0</a>.
  short: N. Clozeau, F. Mattesini, Probability Theory and Related Fields 190 (2024)
    485–541.
corr_author: '1'
date_created: 2024-01-14T23:00:57Z
date_published: 2024-10-01T00:00:00Z
date_updated: 2025-09-04T11:43:43Z
day: '01'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s00440-023-01254-0
ec_funded: 1
external_id:
  arxiv:
  - '2303.00353'
  isi:
  - '001136206200002'
file:
- access_level: open_access
  checksum: 34f44cad6a210ff66791ee37e590af2c
  content_type: application/pdf
  creator: dernst
  date_created: 2025-01-09T08:10:54Z
  date_updated: 2025-01-09T08:10:54Z
  file_id: '18788'
  file_name: 2024_ProbTheoryRelatFields_Clozeau.pdf
  file_size: 880117
  relation: main_file
  success: 1
file_date_updated: 2025-01-09T08:10:54Z
has_accepted_license: '1'
intvolume: '       190'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 485-541
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
  call_identifier: H2020
  grant_number: '948819'
  name: Bridging Scales in Random Materials
publication: Probability Theory and Related Fields
publication_identifier:
  eissn:
  - 1432-2064
  issn:
  - 0178-8051
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Annealed quantitative estimates for the quadratic 2D-discrete random matching
  problem
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 190
year: '2024'
...
---
APC_amount: 3393,38 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '14802'
abstract:
- lang: eng
  text: Frequency-stable lasers form the back bone of precision measurements in science
    and technology. Such lasers typically attain their stability through frequency
    locking to reference cavities. State-of-the-art locking performances to date had
    been achieved using frequency modulation based methods, complemented with active
    drift cancellation systems. We demonstrate an all passive, modulation-free laser-cavity
    locking technique (squash locking) that utilizes changes in spatial beam ellipticity
    for error signal generation, and a coherent polarization post-selection for noise
    resilience. By comparing two identically built proof-of-principle systems, we
    show a frequency locking instability of 5×10<jats:sup>−7</jats:sup> relative to
    the cavity linewidth at 10 s averaging. The results surpass the demonstrated performances
    of methods engineered over the last five decades, potentially enabling an advancement
    in the precision control of lasers, while creating avenues for bridging the performance
    gaps between industrial grade lasers with scientific ones due to the afforded
    simplicity and scalability.
acknowledgement: We thank Rishabh Sahu and Sebastian Wald for technical contributions
  to the experiment. Funding by Institute of Science and Technology Austria.
article_processing_charge: Yes
article_type: original
author:
- first_name: Fritz R
  full_name: Diorico, Fritz R
  id: 2E054C4C-F248-11E8-B48F-1D18A9856A87
  last_name: Diorico
  orcid: 0000-0002-4947-8924
- first_name: Artem
  full_name: Zhutov, Artem
  id: 0f02ed6a-b514-11ee-b891-8379c5f19cb7
  last_name: Zhutov
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
citation:
  ama: 'Diorico FR, Zhutov A, Hosten O. Laser-cavity locking utilizing beam ellipticity:
    accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth.
    <i>Optica</i>. 2024;11(1):26-31. doi:<a href="https://doi.org/10.1364/optica.507451">10.1364/optica.507451</a>'
  apa: 'Diorico, F. R., Zhutov, A., &#38; Hosten, O. (2024). Laser-cavity locking
    utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative
    to cavity linewidth. <i>Optica</i>. Optica Publishing Group. <a href="https://doi.org/10.1364/optica.507451">https://doi.org/10.1364/optica.507451</a>'
  chicago: 'Diorico, Fritz R, Artem Zhutov, and Onur Hosten. “Laser-Cavity Locking
    Utilizing Beam Ellipticity: Accessing the 10<sup>−7</sup> Instability Scale Relative
    to Cavity Linewidth.” <i>Optica</i>. Optica Publishing Group, 2024. <a href="https://doi.org/10.1364/optica.507451">https://doi.org/10.1364/optica.507451</a>.'
  ieee: 'F. R. Diorico, A. Zhutov, and O. Hosten, “Laser-cavity locking utilizing
    beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to
    cavity linewidth,” <i>Optica</i>, vol. 11, no. 1. Optica Publishing Group, pp.
    26–31, 2024.'
  ista: 'Diorico FR, Zhutov A, Hosten O. 2024. Laser-cavity locking utilizing beam
    ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth.
    Optica. 11(1), 26–31.'
  mla: 'Diorico, Fritz R., et al. “Laser-Cavity Locking Utilizing Beam Ellipticity:
    Accessing the 10<sup>−7</sup> Instability Scale Relative to Cavity Linewidth.”
    <i>Optica</i>, vol. 11, no. 1, Optica Publishing Group, 2024, pp. 26–31, doi:<a
    href="https://doi.org/10.1364/optica.507451">10.1364/optica.507451</a>.'
  short: F.R. Diorico, A. Zhutov, O. Hosten, Optica 11 (2024) 26–31.
corr_author: '1'
date_created: 2024-01-15T10:25:38Z
date_published: 2024-01-20T00:00:00Z
date_updated: 2025-09-04T12:13:27Z
day: '20'
ddc:
- '530'
department:
- _id: OnHo
doi: 10.1364/optica.507451
external_id:
  isi:
  - '001202817000004'
file:
- access_level: open_access
  checksum: eb99ca7d0fe73e22f121875175546ed7
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-17T08:53:16Z
  date_updated: 2024-01-17T08:53:16Z
  file_id: '14824'
  file_name: 2023_Optica_Diorico.pdf
  file_size: 4558986
  relation: main_file
  success: 1
file_date_updated: 2024-01-17T08:53:16Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: '1'
keyword:
- Atomic and Molecular Physics
- and Optics
- Electronic
- Optical and Magnetic Materials
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 26-31
publication: Optica
publication_identifier:
  issn:
  - 2334-2536
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup>
  instability scale relative to cavity linewidth'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 11
year: '2024'
...
---
_id: '14820'
abstract:
- lang: eng
  text: "We consider a natural problem dealing with weighted packet selection across
    a rechargeable link, which e.g., finds applications in cryptocurrency networks.
    The capacity of a link (u, v) is determined by how many nodes u and v allocate
    for this link. Specifically, the input is a finite ordered sequence of packets
    that arrive in both directions along a link. Given (u, v) and a packet of weight
    x going from u to v, node u can either accept or reject the packet. If u accepts
    the packet, the capacity on link (u, v) decreases by x. Correspondingly, v's capacity
    on \r\n increases by x. If a node rejects the packet, this will entail a cost
    affinely linear in the weight of the packet. A link is “rechargeable” in the sense
    that the total capacity of the link has to remain constant, but the allocation
    of capacity at the ends of the link can depend arbitrarily on the nodes' decisions.
    The goal is to minimise the sum of the capacity injected into the link and the
    cost of rejecting packets. We show that the problem is NP-hard, but can be approximated
    efficiently with a ratio of (1+E) . (1+3)  for some arbitrary E>0."
acknowledgement: We thank Mahsa Bastankhah and Mohammad Ali Maddah-Ali for fruitful
  discussions about different variants of the problem. This work is supported by the
  European Research Council (ERC) Consolidator Project 864228 (AdjustNet), 2020-2025,
  the ERC CoG 863818 (ForM-SMArt), and the German Research Foundation (DFG) grant
  470029389 (FlexNets), 2021-2024.
article_number: '114353'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Stefan
  full_name: Schmid, Stefan
  last_name: Schmid
- first_name: Jakub
  full_name: Svoboda, Jakub
  id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
  last_name: Svoboda
  orcid: 0000-0002-1419-3267
- first_name: Michelle X
  full_name: Yeo, Michelle X
  id: 2D82B818-F248-11E8-B48F-1D18A9856A87
  last_name: Yeo
  orcid: 0009-0001-3676-4809
citation:
  ama: 'Schmid S, Svoboda J, Yeo MX. Weighted packet selection for rechargeable links
    in cryptocurrency networks: Complexity and approximation. <i>Theoretical Computer
    Science</i>. 2024;989. doi:<a href="https://doi.org/10.1016/j.tcs.2023.114353">10.1016/j.tcs.2023.114353</a>'
  apa: 'Schmid, S., Svoboda, J., &#38; Yeo, M. X. (2024). Weighted packet selection
    for rechargeable links in cryptocurrency networks: Complexity and approximation.
    <i>Theoretical Computer Science</i>. Elsevier. <a href="https://doi.org/10.1016/j.tcs.2023.114353">https://doi.org/10.1016/j.tcs.2023.114353</a>'
  chicago: 'Schmid, Stefan, Jakub Svoboda, and Michelle X Yeo. “Weighted Packet Selection
    for Rechargeable Links in Cryptocurrency Networks: Complexity and Approximation.”
    <i>Theoretical Computer Science</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.tcs.2023.114353">https://doi.org/10.1016/j.tcs.2023.114353</a>.'
  ieee: 'S. Schmid, J. Svoboda, and M. X. Yeo, “Weighted packet selection for rechargeable
    links in cryptocurrency networks: Complexity and approximation,” <i>Theoretical
    Computer Science</i>, vol. 989. Elsevier, 2024.'
  ista: 'Schmid S, Svoboda J, Yeo MX. 2024. Weighted packet selection for rechargeable
    links in cryptocurrency networks: Complexity and approximation. Theoretical Computer
    Science. 989, 114353.'
  mla: 'Schmid, Stefan, et al. “Weighted Packet Selection for Rechargeable Links in
    Cryptocurrency Networks: Complexity and Approximation.” <i>Theoretical Computer
    Science</i>, vol. 989, 114353, Elsevier, 2024, doi:<a href="https://doi.org/10.1016/j.tcs.2023.114353">10.1016/j.tcs.2023.114353</a>.'
  short: S. Schmid, J. Svoboda, M.X. Yeo, Theoretical Computer Science 989 (2024).
corr_author: '1'
date_created: 2024-01-16T13:40:41Z
date_published: 2024-03-21T00:00:00Z
date_updated: 2025-12-02T14:02:37Z
day: '21'
ddc:
- '000'
department:
- _id: KrCh
- _id: KrPi
doi: 10.1016/j.tcs.2023.114353
ec_funded: 1
external_id:
  isi:
  - '001168211400001'
file:
- access_level: open_access
  checksum: efd5b7e738bf845312ba53889a3e13e4
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-16T12:02:25Z
  date_updated: 2024-07-16T12:02:25Z
  file_id: '17263'
  file_name: 2024_TheorComputerScience_Schmid.pdf
  file_size: 603570
  relation: main_file
  success: 1
file_date_updated: 2024-07-16T12:02:25Z
has_accepted_license: '1'
intvolume: '       989'
isi: 1
keyword:
- General Computer Science
- Theoretical Computer Science
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Theoretical Computer Science
publication_identifier:
  issn:
  - 0304-3975
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  record:
  - id: '19985'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'Weighted packet selection for rechargeable links in cryptocurrency networks:
  Complexity and approximation'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 989
year: '2024'
...
---
_id: '14826'
abstract:
- lang: eng
  text: The plant-signaling molecule auxin triggers fast and slow cellular responses
    across land plants and algae. The nuclear auxin pathway mediates gene expression
    and controls growth and development in land plants, but this pathway is absent
    from algal sister groups. Several components of rapid responses have been identified
    in Arabidopsis, but it is unknown if these are part of a conserved mechanism.
    We recently identified a fast, proteome-wide phosphorylation response to auxin.
    Here, we show that this response occurs across 5 land plant and algal species
    and converges on a core group of shared targets. We found conserved rapid physiological
    responses to auxin in the same species and identified rapidly accelerated fibrosarcoma
    (RAF)-like protein kinases as central mediators of auxin-triggered phosphorylation
    across species. Genetic analysis connects this kinase to both auxin-triggered
    protein phosphorylation and rapid cellular response, thus identifying an ancient
    mechanism for fast auxin responses in the green lineage.
acknowledgement: 'We are grateful to Asuka Shitaku and Eri Koide for generating and
  sharing the Marchantia PRAF-mCitrine line and Peng-Cheng Wang for sharing the Arabidopsis
  raf mutant. We are grateful to our team members for discussions and helpful advice.
  This work was supported by funding from the Netherlands Organization for Scientific
  Research (NWO): VICI grant 865.14.001 and ENW-KLEIN OCENW.KLEIN.027 grants to D.W.;
  VENI grant VI.VENI.212.003 to A.K.; the European Research Council AdG DIRNDL (contract
  number 833867) to D.W.; CoG CATCH to J.S.; StG CELLONGATE (contract 803048) to M.F.;
  and AdG ETAP (contract 742985) to J.F.; MEXT KAKENHI grant number JP19H05675 to
  T.K.; JSPS KAKENHI grant number JP20H03275 to R.N.; Takeda Science Foundation to
  R.N.; and the Austrian Science Fund (FWF, P29988) to J.F.'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Andre
  full_name: Kuhn, Andre
  last_name: Kuhn
- first_name: Mark
  full_name: Roosjen, Mark
  last_name: Roosjen
- first_name: Sumanth
  full_name: Mutte, Sumanth
  last_name: Mutte
- first_name: Shiv Mani
  full_name: Dubey, Shiv Mani
  last_name: Dubey
- first_name: Vanessa Polet
  full_name: Carrillo Carrasco, Vanessa Polet
  last_name: Carrillo Carrasco
- first_name: Sjef
  full_name: Boeren, Sjef
  last_name: Boeren
- first_name: Aline
  full_name: Monzer, Aline
  id: 2DB5D88C-D7B3-11E9-B8FD-7907E6697425
  last_name: Monzer
- first_name: Jasper
  full_name: Koehorst, Jasper
  last_name: Koehorst
- first_name: Takayuki
  full_name: Kohchi, Takayuki
  last_name: Kohchi
- first_name: Ryuichi
  full_name: Nishihama, Ryuichi
  last_name: Nishihama
- first_name: Matyas
  full_name: Fendrych, Matyas
  id: 43905548-F248-11E8-B48F-1D18A9856A87
  last_name: Fendrych
  orcid: 0000-0002-9767-8699
- first_name: Joris
  full_name: Sprakel, Joris
  last_name: Sprakel
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
citation:
  ama: Kuhn A, Roosjen M, Mutte S, et al. RAF-like protein kinases mediate a deeply
    conserved, rapid auxin response. <i>Cell</i>. 2024;187(1):130-148.e17. doi:<a
    href="https://doi.org/10.1016/j.cell.2023.11.021">10.1016/j.cell.2023.11.021</a>
  apa: Kuhn, A., Roosjen, M., Mutte, S., Dubey, S. M., Carrillo Carrasco, V. P., Boeren,
    S., … Weijers, D. (2024). RAF-like protein kinases mediate a deeply conserved,
    rapid auxin response. <i>Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.cell.2023.11.021">https://doi.org/10.1016/j.cell.2023.11.021</a>
  chicago: Kuhn, Andre, Mark Roosjen, Sumanth Mutte, Shiv Mani Dubey, Vanessa Polet
    Carrillo Carrasco, Sjef Boeren, Aline Monzer, et al. “RAF-like Protein Kinases
    Mediate a Deeply Conserved, Rapid Auxin Response.” <i>Cell</i>. Elsevier, 2024.
    <a href="https://doi.org/10.1016/j.cell.2023.11.021">https://doi.org/10.1016/j.cell.2023.11.021</a>.
  ieee: A. Kuhn <i>et al.</i>, “RAF-like protein kinases mediate a deeply conserved,
    rapid auxin response,” <i>Cell</i>, vol. 187, no. 1. Elsevier, p. 130–148.e17,
    2024.
  ista: Kuhn A, Roosjen M, Mutte S, Dubey SM, Carrillo Carrasco VP, Boeren S, Monzer
    A, Koehorst J, Kohchi T, Nishihama R, Fendrych M, Sprakel J, Friml J, Weijers
    D. 2024. RAF-like protein kinases mediate a deeply conserved, rapid auxin response.
    Cell. 187(1), 130–148.e17.
  mla: Kuhn, Andre, et al. “RAF-like Protein Kinases Mediate a Deeply Conserved, Rapid
    Auxin Response.” <i>Cell</i>, vol. 187, no. 1, Elsevier, 2024, p. 130–148.e17,
    doi:<a href="https://doi.org/10.1016/j.cell.2023.11.021">10.1016/j.cell.2023.11.021</a>.
  short: A. Kuhn, M. Roosjen, S. Mutte, S.M. Dubey, V.P. Carrillo Carrasco, S. Boeren,
    A. Monzer, J. Koehorst, T. Kohchi, R. Nishihama, M. Fendrych, J. Sprakel, J. Friml,
    D. Weijers, Cell 187 (2024) 130–148.e17.
date_created: 2024-01-17T12:45:40Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2026-04-07T11:48:32Z
day: '04'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.cell.2023.11.021
ec_funded: 1
external_id:
  isi:
  - '001152705700001'
  pmid:
  - '38128538'
file:
- access_level: open_access
  checksum: 06fd236a9ee0b46ccb05f44695bfc34b
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-22T13:41:41Z
  date_updated: 2024-01-22T13:41:41Z
  file_id: '14874'
  file_name: 2024_Cell_Kuhn.pdf
  file_size: 13194060
  relation: main_file
  success: 1
file_date_updated: 2024-01-22T13:41:41Z
has_accepted_license: '1'
intvolume: '       187'
isi: 1
issue: '1'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 130-148.e17
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 262EF96E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P29988
  name: RNA-directed DNA methylation in plant development
publication: Cell
publication_identifier:
  eissn:
  - 1097-4172
  issn:
  - 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  record:
  - id: '19395'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: RAF-like protein kinases mediate a deeply conserved, rapid auxin response
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 187
year: '2024'
...
---
_id: '14828'
abstract:
- lang: eng
  text: Production of hydrogen at large scale requires development of non-noble, inexpensive,
    and high-performing catalysts for constructing water-splitting devices. Herein,
    we report the synthesis of Zn-doped NiO heterostructure (ZnNiO) catalysts at room
    temperature via a coprecipitation method followed by drying (at 80 °C, 6 h) and
    calcination at an elevated temperature of 400 °C for 5 h under three distinct
    conditions, namely, air, N2, and vacuum. The vacuum-synthesized catalyst demonstrates
    a low overpotential of 88 mV at −10 mA cm–2 and a small Tafel slope of 73 mV dec–1
    suggesting relatively higher charge transfer kinetics for hydrogen evolution reactions
    (HER) compared with the specimens synthesized under N2 or O2 atmosphere. It also
    demonstrates an oxygen evolution (OER) overpotential of 260 mV at 10 mA cm–2 with
    a low Tafel slope of 63 mV dec–1. In a full-cell water-splitting device, the vacuum-synthesized
    ZnNiO heterostructure demonstrates a cell voltage of 1.94 V at 50 mA cm–2 and
    shows remarkable stability over 24 h at a high current density of 100 mA cm–2.
    It is also demonstrated in this study that Zn-doping, surface, and interface engineering
    in transition-metal oxides play a crucial role in efficient electrocatalytic water
    splitting. Also, the results obtained from density functional theory (DFT + U
    = 0–8 eV), where U is the on-site Coulomb repulsion parameter also known as Hubbard
    U, based electronic structure calculations confirm that Zn doping constructively
    modifies the electronic structure, in both the valence band and the conduction
    band, and found to be suitable in tailoring the carrier’s effective masses of
    electrons and holes. The decrease in electron’s effective masses together with
    large differences between the effective masses of electrons and holes is noticed,
    which is found to be mainly responsible for achieving the best water-splitting
    performance from a 9% Zn-doped NiO sample prepared under vacuum.
acknowledgement: This work was supported by the Technology Innovation Program (20011622,
  Development of Battery System Applied High-Efficiency Heat Control Polymer and Part
  Component) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea). Author
  acknowledge to Prof. Tsunehiro Takeuchi from Toyota Technological Institute, Nagoya,
  Japan for the support of computational resources.
article_processing_charge: No
article_type: original
author:
- first_name: Gundegowda Kalligowdanadoddi
  full_name: Kiran, Gundegowda Kalligowdanadoddi
  last_name: Kiran
- first_name: Saurabh
  full_name: Singh, Saurabh
  id: 12d625da-9cb3-11ed-9667-af09d37d3f0a
  last_name: Singh
  orcid: 0000-0003-2209-5269
- first_name: Neelima
  full_name: Mahato, Neelima
  last_name: Mahato
- first_name: Thupakula Venkata Madhukar
  full_name: Sreekanth, Thupakula Venkata Madhukar
  last_name: Sreekanth
- first_name: Gowra Raghupathy
  full_name: Dillip, Gowra Raghupathy
  last_name: Dillip
- first_name: Kisoo
  full_name: Yoo, Kisoo
  last_name: Yoo
- first_name: Jonghoon
  full_name: Kim, Jonghoon
  last_name: Kim
citation:
  ama: Kiran GK, Singh S, Mahato N, et al. Interface engineering modulation combined
    with electronic structure modification of Zn-doped NiO heterostructure for efficient
    water-splitting activity. <i>ACS Applied Energy Materials</i>. 2024;7(1):214-229.
    doi:<a href="https://doi.org/10.1021/acsaem.3c02519">10.1021/acsaem.3c02519</a>
  apa: Kiran, G. K., Singh, S., Mahato, N., Sreekanth, T. V. M., Dillip, G. R., Yoo,
    K., &#38; Kim, J. (2024). Interface engineering modulation combined with electronic
    structure modification of Zn-doped NiO heterostructure for efficient water-splitting
    activity. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a href="https://doi.org/10.1021/acsaem.3c02519">https://doi.org/10.1021/acsaem.3c02519</a>
  chicago: Kiran, Gundegowda Kalligowdanadoddi, Saurabh Singh, Neelima Mahato, Thupakula
    Venkata Madhukar Sreekanth, Gowra Raghupathy Dillip, Kisoo Yoo, and Jonghoon Kim.
    “Interface Engineering Modulation Combined with Electronic Structure Modification
    of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity.” <i>ACS
    Applied Energy Materials</i>. American Chemical Society, 2024. <a href="https://doi.org/10.1021/acsaem.3c02519">https://doi.org/10.1021/acsaem.3c02519</a>.
  ieee: G. K. Kiran <i>et al.</i>, “Interface engineering modulation combined with
    electronic structure modification of Zn-doped NiO heterostructure for efficient
    water-splitting activity,” <i>ACS Applied Energy Materials</i>, vol. 7, no. 1.
    American Chemical Society, pp. 214–229, 2024.
  ista: Kiran GK, Singh S, Mahato N, Sreekanth TVM, Dillip GR, Yoo K, Kim J. 2024.
    Interface engineering modulation combined with electronic structure modification
    of Zn-doped NiO heterostructure for efficient water-splitting activity. ACS Applied
    Energy Materials. 7(1), 214–229.
  mla: Kiran, Gundegowda Kalligowdanadoddi, et al. “Interface Engineering Modulation
    Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure
    for Efficient Water-Splitting Activity.” <i>ACS Applied Energy Materials</i>,
    vol. 7, no. 1, American Chemical Society, 2024, pp. 214–29, doi:<a href="https://doi.org/10.1021/acsaem.3c02519">10.1021/acsaem.3c02519</a>.
  short: G.K. Kiran, S. Singh, N. Mahato, T.V.M. Sreekanth, G.R. Dillip, K. Yoo, J.
    Kim, ACS Applied Energy Materials 7 (2024) 214–229.
corr_author: '1'
date_created: 2024-01-17T12:48:35Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2024-10-09T21:07:53Z
day: '08'
department:
- _id: MaIb
doi: 10.1021/acsaem.3c02519
external_id:
  isi:
  - '001138342900001'
intvolume: '         7'
isi: 1
issue: '1'
keyword:
- Electrical and Electronic Engineering
- Materials Chemistry
- Electrochemistry
- Energy Engineering and Power Technology
- Chemical Engineering (miscellaneous)
language:
- iso: eng
month: '01'
oa_version: None
page: 214-229
publication: ACS Applied Energy Materials
publication_identifier:
  issn:
  - 2574-0962
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interface engineering modulation combined with electronic structure modification
  of Zn-doped NiO heterostructure for efficient water-splitting activity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2024'
...
---
_id: '14834'
abstract:
- lang: eng
  text: Bacteria divide by binary fission. The protein machine responsible for this
    process is the divisome, a transient assembly of more than 30 proteins in and
    on the surface of the cytoplasmic membrane. Together, they constrict the cell
    envelope and remodel the peptidoglycan layer to eventually split the cell into
    two. For Escherichia coli, most molecular players involved in this process have
    probably been identified, but obtaining the quantitative information needed for
    a mechanistic understanding can often not be achieved from experiments in vivo
    alone. Since the discovery of the Z-ring more than 30 years ago, in vitro reconstitution
    experiments have been crucial to shed light on molecular processes normally hidden
    in the complex environment of the living cell. In this review, we summarize how
    rebuilding the divisome from purified components – or at least parts of it - have
    been instrumental to obtain the detailed mechanistic understanding of the bacterial
    cell division machinery that we have today.
acknowledgement: We acknowledge members of the Loose laboratory at ISTA for helpful
  discussions—in particular M. Kojic for his insightful comments. This work was supported
  by the Austrian Science Fund (FWF P34607) to M.L.
article_number: '151380'
article_processing_charge: Yes
article_type: review
author:
- first_name: Philipp
  full_name: Radler, Philipp
  id: 40136C2A-F248-11E8-B48F-1D18A9856A87
  last_name: Radler
  orcid: '0000-0001-9198-2182 '
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
citation:
  ama: 'Radler P, Loose M. A dynamic duo: Understanding the roles of FtsZ and FtsA
    for Escherichia coli cell division through in vitro approaches. <i>European Journal
    of Cell Biology</i>. 2024;103(1). doi:<a href="https://doi.org/10.1016/j.ejcb.2023.151380">10.1016/j.ejcb.2023.151380</a>'
  apa: 'Radler, P., &#38; Loose, M. (2024). A dynamic duo: Understanding the roles
    of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches.
    <i>European Journal of Cell Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.ejcb.2023.151380">https://doi.org/10.1016/j.ejcb.2023.151380</a>'
  chicago: 'Radler, Philipp, and Martin Loose. “A Dynamic Duo: Understanding the Roles
    of FtsZ and FtsA for Escherichia Coli Cell Division through in Vitro Approaches.”
    <i>European Journal of Cell Biology</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.ejcb.2023.151380">https://doi.org/10.1016/j.ejcb.2023.151380</a>.'
  ieee: 'P. Radler and M. Loose, “A dynamic duo: Understanding the roles of FtsZ and
    FtsA for Escherichia coli cell division through in vitro approaches,” <i>European
    Journal of Cell Biology</i>, vol. 103, no. 1. Elsevier, 2024.'
  ista: 'Radler P, Loose M. 2024. A dynamic duo: Understanding the roles of FtsZ and
    FtsA for Escherichia coli cell division through in vitro approaches. European
    Journal of Cell Biology. 103(1), 151380.'
  mla: 'Radler, Philipp, and Martin Loose. “A Dynamic Duo: Understanding the Roles
    of FtsZ and FtsA for Escherichia Coli Cell Division through in Vitro Approaches.”
    <i>European Journal of Cell Biology</i>, vol. 103, no. 1, 151380, Elsevier, 2024,
    doi:<a href="https://doi.org/10.1016/j.ejcb.2023.151380">10.1016/j.ejcb.2023.151380</a>.'
  short: P. Radler, M. Loose, European Journal of Cell Biology 103 (2024).
corr_author: '1'
date_created: 2024-01-18T08:16:43Z
date_published: 2024-03-01T00:00:00Z
date_updated: 2025-09-04T11:45:31Z
day: '01'
ddc:
- '570'
department:
- _id: MaLo
doi: 10.1016/j.ejcb.2023.151380
external_id:
  isi:
  - '001166216800001'
  pmid:
  - '38218128'
file:
- access_level: open_access
  checksum: 5d170abbc87585205c010657e4552360
  content_type: application/pdf
  creator: dernst
  date_created: 2024-07-16T12:07:20Z
  date_updated: 2024-07-16T12:07:20Z
  file_id: '17265'
  file_name: 2024_EJCB_Radler.pdf
  file_size: 9995304
  relation: main_file
  success: 1
file_date_updated: 2024-07-16T12:07:20Z
has_accepted_license: '1'
intvolume: '       103'
isi: 1
issue: '1'
keyword:
- Cell Biology
- General Medicine
- Histology
- Pathology and Forensic Medicine
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: fc38323b-9c52-11eb-aca3-ff8afb4a011d
  grant_number: P34607
  name: In vitro reconstitution of bacterial cell division
publication: European Journal of Cell Biology
publication_identifier:
  issn:
  - 0171-9335
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli
  cell division through in vitro approaches'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 103
year: '2024'
...
---
OA_place: publisher
OA_type: hybrid
_id: '14841'
abstract:
- lang: eng
  text: De novo heterozygous variants in KCNC2 encoding the voltage-gated potassium
    (K+) channel subunit Kv3.2 are a recently described cause of developmental and
    epileptic encephalopathy (DEE). A de novo variant in KCNC2 c.374G > A (p.Cys125Tyr)
    was identified via exome sequencing in a patient with DEE. Relative to wild-type
    Kv3.2, Kv3.2-p.Cys125Tyr induces K+ currents exhibiting a large hyperpolarizing
    shift in the voltage dependence of activation, accelerated activation, and delayed
    deactivation consistent with a relative stabilization of the open conformation,
    along with increased current density. Leveraging the cryogenic electron microscopy
    (cryo-EM) structure of Kv3.1, molecular dynamic simulations suggest that a strong
    π-π stacking interaction between the variant Tyr125 and Tyr156 in the α-6 helix
    of the T1 domain promotes a relative stabilization of the open conformation of
    the channel, which underlies the observed gain of function. A multicompartment
    computational model of a Kv3-expressing parvalbumin-positive cerebral cortex fast-spiking
    γ-aminobutyric acidergic (GABAergic) interneuron (PV-IN) demonstrates how the
    Kv3.2-Cys125Tyr variant impairs neuronal excitability and dysregulates inhibition
    in cerebral cortex circuits to explain the resulting epilepsy.
acknowledgement: This work was supported by an ERC Consolidator Grant (SYNAPSEEK)
  to T.P.V., the NOMIS Foundation through the NOMIS Fellowships program at IST Austria
  to C.B.C., a Jefferson Synaptic Biology Center Pilot Project Grant to M.C., NIH
  NINDS U54 NS108874 (PI, Alfred L. George), and NIH NINDS R01 NS122887 to E.M.G.
  The computations were enabled by resources provided by the Swedish National Infrastructure
  for Computing (SNIC) at the PDC Center for High-Performance Computing, KTH Royal
  Institute of Technology, partially funded by the Swedish Research Council through
  grant agreement no. 2018-05973. We thank Akshay Sridhar for the fruitful discussion
  of the project.
article_number: e2307776121
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Jerome
  full_name: Clatot, Jerome
  last_name: Clatot
- first_name: Christopher
  full_name: Currin, Christopher
  id: e8321fc5-3091-11eb-8a53-83f309a11ac9
  last_name: Currin
  orcid: 0000-0002-4809-5059
- first_name: Qiansheng
  full_name: Liang, Qiansheng
  last_name: Liang
- first_name: Tanadet
  full_name: Pipatpolkai, Tanadet
  last_name: Pipatpolkai
- first_name: Shavonne L.
  full_name: Massey, Shavonne L.
  last_name: Massey
- first_name: Ingo
  full_name: Helbig, Ingo
  last_name: Helbig
- first_name: Lucie
  full_name: Delemotte, Lucie
  last_name: Delemotte
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
- first_name: Manuel
  full_name: Covarrubias, Manuel
  last_name: Covarrubias
- first_name: Ethan M.
  full_name: Goldberg, Ethan M.
  last_name: Goldberg
citation:
  ama: Clatot J, Currin C, Liang Q, et al. A structurally precise mechanism links
    an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
    <i>Proceedings of the National Academy of Sciences of the United States of America</i>.
    2024;121(3). doi:<a href="https://doi.org/10.1073/pnas.2307776121">10.1073/pnas.2307776121</a>
  apa: Clatot, J., Currin, C., Liang, Q., Pipatpolkai, T., Massey, S. L., Helbig,
    I., … Goldberg, E. M. (2024). A structurally precise mechanism links an epilepsy-associated
    KCNC2 potassium channel mutation to interneuron dysfunction. <i>Proceedings of
    the National Academy of Sciences of the United States of America</i>. National
    Academy of Sciences. <a href="https://doi.org/10.1073/pnas.2307776121">https://doi.org/10.1073/pnas.2307776121</a>
  chicago: Clatot, Jerome, Christopher Currin, Qiansheng Liang, Tanadet Pipatpolkai,
    Shavonne L. Massey, Ingo Helbig, Lucie Delemotte, Tim P Vogels, Manuel Covarrubias,
    and Ethan M. Goldberg. “A Structurally Precise Mechanism Links an Epilepsy-Associated
    KCNC2 Potassium Channel Mutation to Interneuron Dysfunction.” <i>Proceedings of
    the National Academy of Sciences of the United States of America</i>. National
    Academy of Sciences, 2024. <a href="https://doi.org/10.1073/pnas.2307776121">https://doi.org/10.1073/pnas.2307776121</a>.
  ieee: J. Clatot <i>et al.</i>, “A structurally precise mechanism links an epilepsy-associated
    KCNC2 potassium channel mutation to interneuron dysfunction,” <i>Proceedings of
    the National Academy of Sciences of the United States of America</i>, vol. 121,
    no. 3. National Academy of Sciences, 2024.
  ista: Clatot J, Currin C, Liang Q, Pipatpolkai T, Massey SL, Helbig I, Delemotte
    L, Vogels TP, Covarrubias M, Goldberg EM. 2024. A structurally precise mechanism
    links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
    Proceedings of the National Academy of Sciences of the United States of America.
    121(3), e2307776121.
  mla: Clatot, Jerome, et al. “A Structurally Precise Mechanism Links an Epilepsy-Associated
    KCNC2 Potassium Channel Mutation to Interneuron Dysfunction.” <i>Proceedings of
    the National Academy of Sciences of the United States of America</i>, vol. 121,
    no. 3, e2307776121, National Academy of Sciences, 2024, doi:<a href="https://doi.org/10.1073/pnas.2307776121">10.1073/pnas.2307776121</a>.
  short: J. Clatot, C. Currin, Q. Liang, T. Pipatpolkai, S.L. Massey, I. Helbig, L.
    Delemotte, T.P. Vogels, M. Covarrubias, E.M. Goldberg, Proceedings of the National
    Academy of Sciences of the United States of America 121 (2024).
date_created: 2024-01-21T23:00:56Z
date_published: 2024-01-16T00:00:00Z
date_updated: 2025-09-04T11:47:47Z
day: '16'
ddc:
- '570'
department:
- _id: TiVo
doi: 10.1073/pnas.2307776121
ec_funded: 1
external_id:
  isi:
  - '001167401000001'
  pmid:
  - '38194456'
file:
- access_level: open_access
  checksum: f498c643be81895dd3a69ee90115a782
  content_type: application/pdf
  creator: dernst
  date_created: 2025-04-23T13:51:16Z
  date_updated: 2025-04-23T13:51:16Z
  file_id: '19613'
  file_name: 2024_PNAS_Clatot.pdf
  file_size: 3060109
  relation: main_file
  success: 1
file_date_updated: 2025-04-23T13:51:16Z
has_accepted_license: '1'
intvolume: '       121'
isi: 1
issue: '3'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 0aacfa84-070f-11eb-9043-d7eb2c709234
  call_identifier: H2020
  grant_number: '819603'
  name: Learning the shape of synaptic plasticity rules for neuronal architectures
    and function through machine learning.
publication: Proceedings of the National Academy of Sciences of the United States
  of America
publication_identifier:
  eissn:
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: 'https://github.com/ChrisCurrin/pv-kcnc2 '
scopus_import: '1'
status: public
title: A structurally precise mechanism links an epilepsy-associated KCNC2 potassium
  channel mutation to interneuron dysfunction
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 121
year: '2024'
...
---
_id: '14842'
abstract:
- lang: eng
  text: Eva Benkova received a PhD in Biophysics at the Institute of Biophysics of
    the Czech Academy of Sciences in 1998. After working as a postdoc at the Max Planck
    Institute in Cologne and the Center for Plant Molecular Biology (ZMBP) in Tübingen,
    she became a group leader at the Plant Systems Biology Department of the Vlaams
    Instituut voor Biotechnologie (VIB) in Gent. In 2012, she transitioned to an Assistant
    Professor position at the Institute of Science and Technology Austria (ISTA) where
    she was later promoted to Professor. Since 2021, she has served as the Dean of
    the ISTA Graduate School. As a plant developmental biologist, she focuses on unraveling
    the molecular mechanisms and principles that underlie hormonal interactions in
    plants. In her current work, she explores the intricate connections between hormones
    and regulatory pathways that mediate the perception of environmental stimuli,
    including abiotic stress and nitrate availability.
article_processing_charge: No
author:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
citation:
  ama: Benková E. <i>Eva Benkova</i>. Vol 34. Elsevier; 2024:R3-R5. doi:<a href="https://doi.org/10.1016/j.cub.2023.11.039">10.1016/j.cub.2023.11.039</a>
  apa: Benková, E. (2024). <i>Eva Benkova</i>. <i>Current Biology</i> (Vol. 34, pp.
    R3–R5). Elsevier. <a href="https://doi.org/10.1016/j.cub.2023.11.039">https://doi.org/10.1016/j.cub.2023.11.039</a>
  chicago: Benková, Eva. <i>Eva Benkova</i>. <i>Current Biology</i>. Vol. 34. Elsevier,
    2024. <a href="https://doi.org/10.1016/j.cub.2023.11.039">https://doi.org/10.1016/j.cub.2023.11.039</a>.
  ieee: E. Benková, <i>Eva Benkova</i>, vol. 34, no. 1. Elsevier, 2024, pp. R3–R5.
  ista: Benková E. 2024. Eva Benkova, Elsevier,p.
  mla: Benková, Eva. “Eva Benkova.” <i>Current Biology</i>, vol. 34, no. 1, Elsevier,
    2024, pp. R3–5, doi:<a href="https://doi.org/10.1016/j.cub.2023.11.039">10.1016/j.cub.2023.11.039</a>.
  short: E. Benková, Eva Benkova, Elsevier, 2024.
corr_author: '1'
date_created: 2024-01-21T23:00:56Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2026-06-18T17:40:39Z
day: '08'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1016/j.cub.2023.11.039
external_id:
  pmid:
  - '38194926'
intvolume: '        34'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cub.2023.11.039
month: '01'
oa: 1
oa_version: Published Version
page: R3-R5
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Eva Benkova
type: other_academic_publication
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
