[{"language":[{"iso":"eng"}],"OA_type":"closed access","date_published":"2025-08-15T00:00:00Z","title":"Reimagining advanced chemistry education: A community-based approach to course design for modern learners","article_processing_charge":"No","intvolume":"       102","_id":"20767","type":"journal_article","date_created":"2025-12-09T14:27:11Z","publication":"Journal of Chemical Education","date_updated":"2025-12-16T12:13:49Z","year":"2025","publication_identifier":{"eissn":["1938-1328"],"issn":["0021-9584"]},"abstract":[{"lang":"eng","text":"Chemistry education at the graduate level and beyond faces the formidable challenge of a boundless and constantly expanding frontier of knowledge on many fronts. While modern learners have an increasingly broad range of resources available at their disposal (including open access text-based references, online videos, training problems, and other digital learning materials), there are comparatively fewer such materials aimed at the highest levels of study. With the goal of producing widely accessible graduate-level learning content, we created a community-based approach to online course design that is easily digestible to meet the expectations of modern learners. Herein, we report the development of an open access Advanced Organic Chemistry video-based online course and several other specialized minicourses using the Synthesis Workshop YouTube channel."}],"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1021/acs.jchemed.5c00555","quality_controlled":"1","oa_version":"None","month":"08","article_type":"original","issue":"9","status":"public","publication_status":"published","page":"3777-3783","citation":{"apa":"Horwitz, M. A., Al-Ahmad, R., Bai, X., Balletti, M., Bellotti, P., Ben-Tal, Y., … Wuitschik, G. (2025). Reimagining advanced chemistry education: A community-based approach to course design for modern learners. <i>Journal of Chemical Education</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">https://doi.org/10.1021/acs.jchemed.5c00555</a>","short":"M.A. Horwitz, R. Al-Ahmad, X. Bai, M. Balletti, P. Bellotti, Y. Ben-Tal, M.W. Campbell, K. Cheasty, S.W.M. Crossley, C.S. Day, P.J. Deneny, K.C. Forbes, E.S. Gogarnoiu, P.S. Grant, R. Halder, G.R. Harris, P. Hernández-Lladó, M. Jouanneau, V. Jost, D.A. Kutateladze, G. Laudadio, C. Liu, A.P. Looby, A. Maestro, T. McCallum, M.D. Palkowitz, J.M. Paolillo, M.W.D. Perry, J. Reisenbauer, C. Reyes, H.A. Sharma, F.K. Sheong, B. Thoma, A.V. Tran, D.N. Tran, F.J. Aguilar Troyano, T. Verheyen, M.P. Walsh, A. Wagner, E.R. Wearing, G. Wuitschik, Journal of Chemical Education 102 (2025) 3777–3783.","mla":"Horwitz, Matthew A., et al. “Reimagining Advanced Chemistry Education: A Community-Based Approach to Course Design for Modern Learners.” <i>Journal of Chemical Education</i>, vol. 102, no. 9, American Chemical Society, 2025, pp. 3777–83, doi:<a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">10.1021/acs.jchemed.5c00555</a>.","ista":"Horwitz MA, Al-Ahmad R, Bai X, Balletti M, Bellotti P, Ben-Tal Y, Campbell MW, Cheasty K, Crossley SWM, Day CS, Deneny PJ, Forbes KC, Gogarnoiu ES, Grant PS, Halder R, Harris GR, Hernández-Lladó P, Jouanneau M, Jost V, Kutateladze DA, Laudadio G, Liu C, Looby AP, Maestro A, McCallum T, Palkowitz MD, Paolillo JM, Perry MWD, Reisenbauer J, Reyes C, Sharma HA, Sheong FK, Thoma B, Tran AV, Tran DN, Aguilar Troyano FJ, Verheyen T, Walsh MP, Wagner A, Wearing ER, Wuitschik G. 2025. Reimagining advanced chemistry education: A community-based approach to course design for modern learners. Journal of Chemical Education. 102(9), 3777–3783.","ama":"Horwitz MA, Al-Ahmad R, Bai X, et al. Reimagining advanced chemistry education: A community-based approach to course design for modern learners. <i>Journal of Chemical Education</i>. 2025;102(9):3777-3783. doi:<a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">10.1021/acs.jchemed.5c00555</a>","chicago":"Horwitz, Matthew A., Reem Al-Ahmad, Xingfeng Bai, Matteo Balletti, Peter Bellotti, Yael Ben-Tal, Mark W. Campbell, et al. “Reimagining Advanced Chemistry Education: A Community-Based Approach to Course Design for Modern Learners.” <i>Journal of Chemical Education</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">https://doi.org/10.1021/acs.jchemed.5c00555</a>.","ieee":"M. A. Horwitz <i>et al.</i>, “Reimagining advanced chemistry education: A community-based approach to course design for modern learners,” <i>Journal of Chemical Education</i>, vol. 102, no. 9. American Chemical Society, pp. 3777–3783, 2025."},"scopus_import":"1","day":"15","author":[{"first_name":"Matthew A.","full_name":"Horwitz, Matthew A.","last_name":"Horwitz"},{"full_name":"Al-Ahmad, Reem","last_name":"Al-Ahmad","first_name":"Reem"},{"last_name":"Bai","full_name":"Bai, Xingfeng","first_name":"Xingfeng"},{"first_name":"Matteo","full_name":"Balletti, Matteo","last_name":"Balletti"},{"last_name":"Bellotti","full_name":"Bellotti, Peter","first_name":"Peter"},{"first_name":"Yael","full_name":"Ben-Tal, Yael","last_name":"Ben-Tal"},{"first_name":"Mark W.","full_name":"Campbell, Mark W.","last_name":"Campbell"},{"first_name":"Kathleen","last_name":"Cheasty","full_name":"Cheasty, Kathleen"},{"first_name":"Steven W. M.","full_name":"Crossley, Steven W. M.","last_name":"Crossley"},{"first_name":"Craig S.","full_name":"Day, Craig S.","last_name":"Day"},{"first_name":"Patrick J.","last_name":"Deneny","full_name":"Deneny, Patrick J."},{"last_name":"Forbes","full_name":"Forbes, Katherine C.","first_name":"Katherine C."},{"last_name":"Gogarnoiu","full_name":"Gogarnoiu, Emma S.","first_name":"Emma S."},{"full_name":"Grant, Phillip S.","last_name":"Grant","first_name":"Phillip S."},{"full_name":"Halder, Riya","last_name":"Halder","first_name":"Riya"},{"full_name":"Harris, Georgia R.","last_name":"Harris","first_name":"Georgia R."},{"last_name":"Hernández-Lladó","full_name":"Hernández-Lladó, Pol","first_name":"Pol"},{"full_name":"Jouanneau, Morgan","last_name":"Jouanneau","first_name":"Morgan"},{"first_name":"Vera","full_name":"Jost, Vera","last_name":"Jost"},{"first_name":"Dennis A.","full_name":"Kutateladze, Dennis A.","last_name":"Kutateladze"},{"last_name":"Laudadio","full_name":"Laudadio, Gabriele","first_name":"Gabriele"},{"first_name":"Chun","full_name":"Liu, Chun","last_name":"Liu"},{"first_name":"Aidan P.","full_name":"Looby, Aidan P.","last_name":"Looby"},{"full_name":"Maestro, Aitor","last_name":"Maestro","first_name":"Aitor"},{"first_name":"Terry","last_name":"McCallum","full_name":"McCallum, Terry"},{"first_name":"Maximilian D.","last_name":"Palkowitz","full_name":"Palkowitz, Maximilian D."},{"first_name":"Joshua M.","last_name":"Paolillo","full_name":"Paolillo, Joshua M."},{"first_name":"Matthew W. D.","full_name":"Perry, Matthew W. D.","last_name":"Perry"},{"full_name":"Reisenbauer, Julia","last_name":"Reisenbauer","id":"51d862e9-36ee-11f0-86d3-8534c85a5496","first_name":"Julia"},{"last_name":"Reyes","full_name":"Reyes, Cesar","first_name":"Cesar"},{"full_name":"Sharma, Hayden A.","last_name":"Sharma","first_name":"Hayden A."},{"first_name":"Fu Kit","last_name":"Sheong","full_name":"Sheong, Fu Kit"},{"first_name":"Benjamin","full_name":"Thoma, Benjamin","last_name":"Thoma"},{"first_name":"Andrew V.","last_name":"Tran","full_name":"Tran, Andrew V."},{"first_name":"Duc N.","last_name":"Tran","full_name":"Tran, Duc N."},{"first_name":"Francisco José","full_name":"Aguilar Troyano, Francisco José","last_name":"Aguilar Troyano"},{"first_name":"Thomas","full_name":"Verheyen, Thomas","last_name":"Verheyen"},{"last_name":"Walsh","full_name":"Walsh, Mark P.","first_name":"Mark P."},{"first_name":"Alicia","last_name":"Wagner","full_name":"Wagner, Alicia"},{"first_name":"Emily R.","full_name":"Wearing, Emily R.","last_name":"Wearing"},{"last_name":"Wuitschik","full_name":"Wuitschik, Georg","first_name":"Georg"}],"volume":102,"publisher":"American Chemical Society"},{"author":[{"first_name":"Predrag","id":"68AA0E5A-AFDA-11E9-9994-141DE6697425","last_name":"Zivadinovic","full_name":"Zivadinovic, Predrag"}],"day":"11","publisher":"Institute of Science and Technology Austria","project":[{"name":"Functional Advantages of Critical Brain Dynamics","grant_number":"M03318","_id":"eb943429-77a9-11ec-83b8-9f471cdf5c67"}],"file":[{"checksum":"aae9d1ed53f7b67f75e289c26a02b72f","embargo":"2026-06-11","creator":"pzivadin","content_type":"application/pdf","file_id":"20778","date_updated":"2026-06-11T22:30:02Z","date_created":"2025-12-10T19:28:20Z","file_name":"2025_Zivadinovic_Predrag_PhD_thesis.pdf","relation":"main_file","file_size":8105379,"access_level":"open_access"},{"checksum":"8a08a3804ce7d9d625fdf1631113da8c","embargo_to":"open_access","creator":"pzivadin","date_created":"2025-12-10T19:28:10Z","date_updated":"2026-06-11T22:30:02Z","file_id":"20779","content_type":"application/zip","relation":"source_file","file_size":8512240,"access_level":"closed","file_name":"2025_Zivadinovic_Predrag_PhD_thesis_source.zip"}],"citation":{"ieee":"P. Zivadinovic, “Scale-free activity as a basis for spatial learning and memory in the brain,” Institute of Science and Technology Austria, 2025.","short":"P. Zivadinovic, Scale-Free Activity as a Basis for Spatial Learning and Memory in the Brain, Institute of Science and Technology Austria, 2025.","apa":"Zivadinovic, P. (2025). <i>Scale-free activity as a basis for spatial learning and memory in the brain</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20777\">https://doi.org/10.15479/AT-ISTA-20777</a>","ama":"Zivadinovic P. Scale-free activity as a basis for spatial learning and memory in the brain. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20777\">10.15479/AT-ISTA-20777</a>","mla":"Zivadinovic, Predrag. <i>Scale-Free Activity as a Basis for Spatial Learning and Memory in the Brain</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20777\">10.15479/AT-ISTA-20777</a>.","ista":"Zivadinovic P. 2025. Scale-free activity as a basis for spatial learning and memory in the brain. Institute of Science and Technology Austria.","chicago":"Zivadinovic, Predrag. “Scale-Free Activity as a Basis for Spatial Learning and Memory in the Brain.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20777\">https://doi.org/10.15479/AT-ISTA-20777</a>."},"alternative_title":["ISTA Thesis"],"page":"104","publication_status":"published","month":"12","oa_version":"Published Version","status":"public","ddc":["570","539","571"],"degree_awarded":"PhD","OA_place":"publisher","doi":"10.15479/AT-ISTA-20777","supervisor":[{"orcid":"0000-0002-5193-4036","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","first_name":"Jozsef L","last_name":"Csicsvari","full_name":"Csicsvari, Jozsef L"}],"department":[{"_id":"GradSch"},{"_id":"JoCs"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","corr_author":"1","oa":1,"publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"My work has been funded through the project \"Functional Advantages of Critical Brain\r\nDynamics\" of the ISTA interdisciplinary fund and through the FWF.\r\n","date_created":"2025-12-10T19:37:41Z","date_updated":"2026-06-11T22:30:03Z","year":"2025","type":"dissertation","_id":"20777","has_accepted_license":"1","file_date_updated":"2026-06-11T22:30:02Z","language":[{"iso":"eng"}],"title":"Scale-free activity as a basis for spatial learning and memory in the brain","article_processing_charge":"No","date_published":"2025-12-11T00:00:00Z"},{"date_updated":"2026-06-10T08:27:48Z","year":"2025","date_created":"2025-12-10T23:40:14Z","file":[{"content_type":"application/zip","date_created":"2025-12-11T10:47:15Z","date_updated":"2025-12-11T10:47:15Z","file_id":"20799","file_name":"Perl_scripts.zip","access_level":"open_access","file_size":4575,"relation":"main_file","checksum":"251e7aab01917c2ad2fbccf465492ea1","success":1,"creator":"llayanaf"},{"access_level":"open_access","file_size":19052849,"relation":"main_file","file_name":"Supplementary_Datasets.zip","date_updated":"2025-12-11T10:52:17Z","file_id":"20800","date_created":"2025-12-11T10:52:17Z","content_type":"application/zip","creator":"llayanaf","success":1,"checksum":"daf1c03149dd170b14e5c8e109ee3c77"},{"creator":"llayanaf","success":1,"checksum":"658d6e95a361b0a3db058b7b4e1733d4","access_level":"open_access","relation":"main_file","file_size":566476,"file_name":"Supplementary_Tables.zip","date_created":"2025-12-11T10:52:11Z","date_updated":"2025-12-11T10:52:11Z","file_id":"20801","content_type":"application/zip"},{"checksum":"2a2b92eb9fade0015719190596a8c5b7","success":1,"creator":"llayanaf","content_type":"text/plain","date_updated":"2025-12-11T11:00:53Z","file_id":"20802","date_created":"2025-12-11T11:00:53Z","file_name":"README.txt","file_size":1204,"relation":"main_file","access_level":"open_access"}],"citation":{"chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">https://doi.org/10.15479/AT-ISTA-20780</a>.","ista":"Layana Franco LA, Toups MA, Vicoso B. 2025. Causes and consequences of sex-chromosome turnovers in Diptera, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>.","mla":"Layana Franco, Lorena Alexandra, et al. <i>Causes and Consequences of Sex-Chromosome Turnovers in Diptera</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>.","ama":"Layana Franco LA, Toups MA, Vicoso B. Causes and consequences of sex-chromosome turnovers in Diptera. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>","short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, (2025).","apa":"Layana Franco, L. A., Toups, M. A., &#38; Vicoso, B. (2025). Causes and consequences of sex-chromosome turnovers in Diptera. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">https://doi.org/10.15479/AT-ISTA-20780</a>","ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Causes and consequences of sex-chromosome turnovers in Diptera.” Institute of Science and Technology Austria, 2025."},"abstract":[{"text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analysed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on the F element (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male-achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes.","lang":"eng"}],"department":[{"_id":"BeVi"}],"author":[{"last_name":"Layana Franco","full_name":"Layana Franco, Lorena Alexandra","id":"02814589-eb8f-11eb-b029-a70074f3f18f","first_name":"Lorena Alexandra","orcid":"0000-0002-1253-6297"},{"last_name":"Toups","full_name":"Toups, Melissa A","orcid":"0000-0002-9752-7380","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","first_name":"Melissa A"},{"full_name":"Vicoso, Beatriz","last_name":"Vicoso","orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz"}],"oa":1,"corr_author":"1","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","publisher":"Institute of Science and Technology Austria","file_date_updated":"2025-12-11T11:00:53Z","date_published":"2025-12-01T00:00:00Z","doi":"10.15479/AT-ISTA-20780","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Causes and consequences of sex-chromosome turnovers in Diptera","article_processing_charge":"No","oa_version":"Published Version","month":"12","has_accepted_license":"1","keyword":["Schizophora","sex chromosomes","sex-chromosome turnover","Diptera","genomic features","out-of-X movement."],"status":"public","_id":"20780","acknowledged_ssus":[{"_id":"ScienComp"}],"type":"research_data"},{"publication_status":"published","citation":{"chicago":"Bao, Jiawei, Sandrine Bony, Daisuke Takasuka, and Caroline J Muller. “Tropics-Wide Intraseasonal Oscillations.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2511549122\">https://doi.org/10.1073/pnas.2511549122</a>.","ista":"Bao J, Bony S, Takasuka D, Muller CJ. 2025. Tropics-wide intraseasonal oscillations. Proceedings of the National Academy of Sciences. 122(48), e2511549122.","mla":"Bao, Jiawei, et al. “Tropics-Wide Intraseasonal Oscillations.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 48, e2511549122, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2511549122\">10.1073/pnas.2511549122</a>.","ama":"Bao J, Bony S, Takasuka D, Muller CJ. Tropics-wide intraseasonal oscillations. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(48). doi:<a href=\"https://doi.org/10.1073/pnas.2511549122\">10.1073/pnas.2511549122</a>","apa":"Bao, J., Bony, S., Takasuka, D., &#38; Muller, C. J. (2025). Tropics-wide intraseasonal oscillations. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2511549122\">https://doi.org/10.1073/pnas.2511549122</a>","short":"J. Bao, S. Bony, D. Takasuka, C.J. Muller, Proceedings of the National Academy of Sciences 122 (2025).","ieee":"J. Bao, S. Bony, D. Takasuka, and C. J. Muller, “Tropics-wide intraseasonal oscillations,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 48. National Academy of Sciences, 2025."},"file":[{"success":1,"checksum":"093a8685170e4a1de9176f68ee449493","creator":"dernst","date_updated":"2025-12-15T09:17:33Z","file_id":"20822","date_created":"2025-12-15T09:17:33Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_size":30890293,"file_name":"2025_PNAS_Bao.pdf"}],"scopus_import":"1","ec_funded":1,"day":"02","related_material":{"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/hidden-in-plain-sight/"}]},"author":[{"full_name":"Bao, Jiawei","last_name":"Bao","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","first_name":"Jiawei"},{"last_name":"Bony","full_name":"Bony, Sandrine","first_name":"Sandrine"},{"first_name":"Daisuke","full_name":"Takasuka, Daisuke","last_name":"Takasuka"},{"first_name":"Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","orcid":"0000-0001-5836-5350","full_name":"Muller, Caroline J","last_name":"Muller"}],"volume":122,"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program"},{"grant_number":"805041","call_identifier":"H2020","_id":"629205d8-2b32-11ec-9570-e1356ff73576","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate"}],"publisher":"National Academy of Sciences","OA_place":"publisher","doi":"10.1073/pnas.2511549122","quality_controlled":"1","oa_version":"Published Version","month":"12","article_type":"original","issue":"48","ddc":["550"],"article_number":"e2511549122","status":"public","publication":"Proceedings of the National Academy of Sciences","date_created":"2025-12-11T10:41:13Z","date_updated":"2026-05-20T08:11:56Z","year":"2025","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"acknowledgement":"J.B. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant agreement No. 101034413). S.B. acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Project Mesoscale organization of tropical convection, grant agreement No 101098063). D.T. acknowledges funding from the Japan Society for the Promotion of Science (JSPS) (Project JSPS Grants-in-Aid for Scientific Research, grant No. JP24K22893). C.M. gratefully acknowledges funding from the ERC under the European Union’s Horizon 2020 research and innovation program (Project organisation of CLoUdS, and implications for Tropical cyclones and for the Energetics of the tropics, in current and in a waRming climate, grant agreement No. 805041). We thank Martin Singh, Steven Sherwood, Bjorn Stevens, and Lokahith Agasthya for helpful discussions. JSPS Core-to-Core Program, “International Core-to-Core Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001)","PlanS_conform":"1","external_id":{"pmid":["41284872"]},"abstract":[{"text":"The tropical climate variability is characterized by various oscillations across a range of timescales. Oscillations that imprint the tropical mean state are generally attributed to slow processes, such as the seasonal cycle or interannual variability. Here, we identify a pronounced tropics-wide intraseasonal oscillation (TWISO) in satellite observations and reanalyses. This oscillation, with a period of 30 to 60 d, is evident across multiple variables and involves interactions between convection, radiation, surface fluxes, and large-scale circulation. It is primarily manifested as convective perturbations in the tropical Indo-Pacific warm pool accompanied by oscillations in the large-scale tropical overturning circulation. Here, we examine the relationship between TWISO, the Madden–Julian Oscillation (MJO), and the instability of radiative-convective equilibrium. Certain phases of TWISO coincide with specific phases of the MJO, suggesting a potential connection between the two. However, although the MJO can amplify the oscillation amplitude of TWISO, it is not essential for TWISO to occur. Finally, due to its broad manifestation across the tropics, TWISO potentially exerts widespread influence on tropical weather and climate at regional scales.","lang":"eng"}],"department":[{"_id":"CaMu"}],"corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"file_date_updated":"2025-12-15T09:17:33Z","OA_type":"hybrid","pmid":1,"date_published":"2025-12-02T00:00:00Z","article_processing_charge":"Yes (in subscription journal)","title":"Tropics-wide intraseasonal oscillations","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"APC_amount":"5651,35 EUR","intvolume":"       122","has_accepted_license":"1","_id":"20795","type":"journal_article"},{"intvolume":"        16","_id":"20796","type":"journal_article","has_accepted_license":"1","OA_type":"gold","language":[{"iso":"eng"}],"file_date_updated":"2025-12-15T09:25:51Z","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_processing_charge":"Yes","title":"BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity","date_published":"2025-11-25T00:00:00Z","pmid":1,"department":[{"_id":"BeVi"}],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We are grateful to Monique Zetka, Nicola Silva, and Yumi Kim, Needhi Bhalla, George Krohne and Rueyling Lin for providing reagents; Scott Kennedy for sharing the multiplexed FISH library; and members of the Max Perutz Labs’ BioOptics facility (Irmgard Fischer, Josef Gotzmann, Thomas Peterbauer, Clara Bodner, and Nick Wedige) for training and support in image acquisition. We also thank the members of the NGS facility at the Vienna Biocenter. This work was funded by the Austrian Science Fund (FWF) SFB projects F 8805-B (VJ), https://doi.org/10.55776/F88, F 8809-B (ITB), and F8810-B (BV). We are also grateful to members of the V. Jantsch laboratory for helpful discussions. Some strains were provided by the Caenorhabditis Genetics Center, which is funded by the National Institutes of Health Office of Research Infrastructure Programs (P40OD010440).","publication_identifier":{"eissn":["2041-1723"]},"year":"2025","date_updated":"2025-12-15T09:28:37Z","publication":"Nature Communications","date_created":"2025-12-11T10:45:06Z","abstract":[{"text":"Rapid prophase chromosome movements ensure faithful alignment of the parental homologous chromosomes and successful synapsis formation during meiosis. These movements are driven by cytoplasmic forces transmitted to the nuclear periphery, where chromosome ends are attached through transmembrane proteins. During many developmental stages a specific genome architecture with chromatin nuclear periphery contacts mediates specific gene expression. Whether chromatin is removed from the nuclear periphery as a consequence of chromosome motions or by a specific mechanism is not fully understood. Here, we identify a mechanism to remove chromatin from the nuclear periphery through vaccinia related kinase (VRK-1)–dependent phosphorylation of Barrier to Autointegration Factor 1 (BAF-1) in Caenorhabditis elegans early prophase of meiosis. Interfering with chromatin removal delays chromosome pairing, impairs synapsis, produces oocytes with abnormal chromosomes and elevated apoptosis. Long read sequencing reveals deletions and duplications in offspring lacking VRK-1 underscoring the importance of the BAF-1–VRK-1 module in preserving genome stability in gametes during rapid chromosome movements.","lang":"eng"}],"external_id":{"pmid":["41290579"]},"PlanS_conform":"1","article_type":"original","month":"11","oa_version":"Published Version","status":"public","article_number":"10446","ddc":["570"],"OA_place":"publisher","quality_controlled":"1","doi":"10.1038/s41467-025-65420-9","author":[{"first_name":"Dimitra","full_name":"Paouneskou, Dimitra","last_name":"Paouneskou"},{"full_name":"Baudrimont, Antoine","last_name":"Baudrimont","first_name":"Antoine"},{"first_name":"Réka K","id":"48D3F8DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8489-9281","last_name":"Kelemen","full_name":"Kelemen, Réka K"},{"full_name":"Elkrewi, Marwan N","last_name":"Elkrewi","orcid":"0000-0002-5328-7231","first_name":"Marwan N","id":"0B46FACA-A8E1-11E9-9BD3-79D1E5697425"},{"last_name":"Graf","full_name":"Graf, Angela","first_name":"Angela"},{"full_name":"Moukbel Ali Aldawla, Shehab","last_name":"Moukbel Ali Aldawla","first_name":"Shehab"},{"full_name":"Kölbl, Claudia","last_name":"Kölbl","first_name":"Claudia"},{"first_name":"Irene","full_name":"Tiemann-Boege, Irene","last_name":"Tiemann-Boege"},{"full_name":"Vicoso, Beatriz","last_name":"Vicoso","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz","orcid":"0000-0002-4579-8306"},{"first_name":"Verena","last_name":"Jantsch","full_name":"Jantsch, Verena"}],"day":"25","publisher":"Springer Nature","project":[{"grant_number":"F8810","_id":"34ae1506-11ca-11ed-8bc3-c14f4c474396","name":"The highjacking of meiosis for asexual reproduction"}],"volume":16,"citation":{"ieee":"D. Paouneskou <i>et al.</i>, “BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","mla":"Paouneskou, Dimitra, et al. “BAF-1–VRK-1 Mediated Release of Meiotic Chromosomes from the Nuclear Periphery Is Important for Genome Integrity.” <i>Nature Communications</i>, vol. 16, 10446, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-65420-9\">10.1038/s41467-025-65420-9</a>.","ama":"Paouneskou D, Baudrimont A, Kelemen RK, et al. BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-65420-9\">10.1038/s41467-025-65420-9</a>","chicago":"Paouneskou, Dimitra, Antoine Baudrimont, Réka K Kelemen, Marwan N Elkrewi, Angela Graf, Shehab Moukbel Ali Aldawla, Claudia Kölbl, Irene Tiemann-Boege, Beatriz Vicoso, and Verena Jantsch. “BAF-1–VRK-1 Mediated Release of Meiotic Chromosomes from the Nuclear Periphery Is Important for Genome Integrity.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-65420-9\">https://doi.org/10.1038/s41467-025-65420-9</a>.","ista":"Paouneskou D, Baudrimont A, Kelemen RK, Elkrewi MN, Graf A, Moukbel Ali Aldawla S, Kölbl C, Tiemann-Boege I, Vicoso B, Jantsch V. 2025. BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. Nature Communications. 16, 10446.","short":"D. Paouneskou, A. Baudrimont, R.K. Kelemen, M.N. Elkrewi, A. Graf, S. Moukbel Ali Aldawla, C. Kölbl, I. Tiemann-Boege, B. Vicoso, V. Jantsch, Nature Communications 16 (2025).","apa":"Paouneskou, D., Baudrimont, A., Kelemen, R. K., Elkrewi, M. N., Graf, A., Moukbel Ali Aldawla, S., … Jantsch, V. (2025). BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-65420-9\">https://doi.org/10.1038/s41467-025-65420-9</a>"},"file":[{"checksum":"a952f7ea050242b79008540de49a0e61","success":1,"creator":"dernst","content_type":"application/pdf","file_id":"20823","date_updated":"2025-12-15T09:25:51Z","date_created":"2025-12-15T09:25:51Z","file_name":"2025_NatureComm_Paouneskou.pdf","file_size":8096309,"relation":"main_file","access_level":"open_access"}],"publication_status":"published","scopus_import":"1","DOAJ_listed":"1"},{"day":"29","author":[{"first_name":"Hannah","last_name":"Seabrook","full_name":"Seabrook, Hannah"},{"last_name":"Lavie","full_name":"Lavie, Emilien","first_name":"Emilien"},{"id":"68011cd2-da32-11ee-a930-b2774c7aba5f","first_name":"Karl T","last_name":"Strömberg","full_name":"Strömberg, Karl T"},{"first_name":"Matthew P.","full_name":"Stafford, Matthew P.","last_name":"Stafford"},{"full_name":"Rubino, Giulia","last_name":"Rubino","first_name":"Giulia"}],"volume":24,"publisher":"American Physical Society","publication_status":"published","citation":{"short":"H. Seabrook, E. Lavie, K.T. Strömberg, M.P. Stafford, G. Rubino, Physical Review Applied 24 (2025).","apa":"Seabrook, H., Lavie, E., Strömberg, K. T., Stafford, M. P., &#38; Rubino, G. (2025). Surpassing the loss-noise robustness trade-off in quantum key distribution. <i>Physical Review Applied</i>. American Physical Society. <a href=\"https://doi.org/10.1103/xq2l-r4r7\">https://doi.org/10.1103/xq2l-r4r7</a>","ista":"Seabrook H, Lavie E, Strömberg KT, Stafford MP, Rubino G. 2025. Surpassing the loss-noise robustness trade-off in quantum key distribution. Physical Review Applied. 24(2), 024072.","chicago":"Seabrook, Hannah, Emilien Lavie, Karl T Strömberg, Matthew P. Stafford, and Giulia Rubino. “Surpassing the Loss-Noise Robustness Trade-off in Quantum Key Distribution.” <i>Physical Review Applied</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/xq2l-r4r7\">https://doi.org/10.1103/xq2l-r4r7</a>.","mla":"Seabrook, Hannah, et al. “Surpassing the Loss-Noise Robustness Trade-off in Quantum Key Distribution.” <i>Physical Review Applied</i>, vol. 24, no. 2, 024072, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/xq2l-r4r7\">10.1103/xq2l-r4r7</a>.","ama":"Seabrook H, Lavie E, Strömberg KT, Stafford MP, Rubino G. Surpassing the loss-noise robustness trade-off in quantum key distribution. <i>Physical Review Applied</i>. 2025;24(2). doi:<a href=\"https://doi.org/10.1103/xq2l-r4r7\">10.1103/xq2l-r4r7</a>","ieee":"H. Seabrook, E. Lavie, K. T. Strömberg, M. P. Stafford, and G. Rubino, “Surpassing the loss-noise robustness trade-off in quantum key distribution,” <i>Physical Review Applied</i>, vol. 24, no. 2. American Physical Society, 2025."},"file":[{"file_id":"20824","date_updated":"2025-12-15T09:39:12Z","date_created":"2025-12-15T09:39:12Z","content_type":"application/pdf","file_size":3028735,"relation":"main_file","access_level":"open_access","file_name":"2025_PhysReviewApplied_Seabrook.pdf","success":1,"checksum":"12ddb0414780f65b8e690fe0e6cfb95e","creator":"dernst"}],"scopus_import":"1","oa_version":"Published Version","article_type":"original","month":"08","article_number":"024072","issue":"2","ddc":["530"],"status":"public","OA_place":"publisher","doi":"10.1103/xq2l-r4r7","quality_controlled":"1","department":[{"_id":"OnHo"}],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2025-12-15T09:40:58Z","year":"2025","publication":"Physical Review Applied","date_created":"2025-12-11T10:46:28Z","acknowledgement":"We thank B. Baragiola, A. Boubriak, M. Clark, M. Jones, and P. Skrzypczyk for useful discussions. H.S. acknowledges financial support from EPSRC Quantum Engineering Centre for Doctoral Training Grant No. EP/SO23607/1. E.L. acknowledges support from the Engineering and Physical Sciences Research Council (EPSRC) Hub in Quantum Computing and Simulation (EP/T001062/1). T.S. acknowledges that they received no funding in support of this research. M.P.S. acknowledges support from the EPSRC Quantum Engineering Centre for Doctoral Training EP/SO23607/1 and the European Commission through Starting Grant No. ERC-2018-STG803665 (PEQEM). G.R. acknowledges support from the Royal Commission for the Exhibition of 1851 through a Research Fellowship, from the European Commission through Starting Grant No. ERC-2018-STG803665 (PEQEM) and Advanced Grant No. ERC-2020-ADG101021085 (FLQuant), and from EPSRC through Standard Proposal Grant No. EP/X016218/1 (Mono-Squeeze).","arxiv":1,"publication_identifier":{"eissn":["2331-7019"]},"PlanS_conform":"1","external_id":{"arxiv":["2412.08694"]},"abstract":[{"text":"Quantum key distribution (QKD) offers a theoretically secure method to share secret keys, yet practical implementations face challenges due to noise and loss over long-distance channels. Traditional QKD protocols require extensive noise compensation, hindering their industrial scalability and lowering the achievable key rates. Alternative protocols encode logical qubits in noise-resilient states but at the cost of using many physical qubits, increasing susceptibility to loss and limiting transmission distance. In this work, we introduce a logical-qubit encoding that uses antisymmetric Bell states in the continuous photonic degrees of freedom, frequency and time. By leveraging the continuous space, we overcome this noise-loss robustness trade-off by minimizing the number of photons per logical qubit while optimizing the encoding resilience over noise fluctuations. We analyze the security of our encoding and demonstrate its robustness compared to existing state-of-the-art protocols. This approach provides a path toward scalable, efficient QKD implementations under realistic noise conditions.","lang":"eng"}],"intvolume":"        24","has_accepted_license":"1","type":"journal_article","_id":"20797","language":[{"iso":"eng"}],"file_date_updated":"2025-12-15T09:39:12Z","OA_type":"hybrid","date_published":"2025-08-29T00:00:00Z","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Surpassing the loss-noise robustness trade-off in quantum key distribution","article_processing_charge":"Yes (in subscription journal)"},{"publication_status":"published","page":"152","alternative_title":["ISTA Thesis"],"citation":{"short":"S. Wald, Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry, Institute of Science and Technology Austria, 2025.","apa":"Wald, S. (2025). <i>Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20798\">https://doi.org/10.15479/AT-ISTA-20798</a>","ista":"Wald S. 2025. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry. Institute of Science and Technology Austria.","chicago":"Wald, Sebastian. “Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20798\">https://doi.org/10.15479/AT-ISTA-20798</a>.","ama":"Wald S. Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20798\">10.15479/AT-ISTA-20798</a>","mla":"Wald, Sebastian. <i>Atoms in a Propagating-Wave Cavity for Squeezed Mach-Zehnder Atom Interferometry</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20798\">10.15479/AT-ISTA-20798</a>.","ieee":"S. Wald, “Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry,” Institute of Science and Technology Austria, 2025."},"file":[{"creator":"swald","embargo":"2026-06-15","checksum":"1be72faf529a5e8a2d03cb3d5f808b77","file_size":47536855,"access_level":"open_access","relation":"main_file","file_name":"2025_Wald_Sebastian_Thesis.pdf","date_created":"2025-12-12T11:53:42Z","date_updated":"2026-06-15T22:30:03Z","file_id":"20809","content_type":"application/pdf"},{"access_level":"closed","relation":"source_file","file_size":40127601,"file_name":"2025_Wald_Sebastian_Thesis.zip","date_created":"2025-12-12T11:54:55Z","file_id":"20810","date_updated":"2026-06-15T22:30:03Z","content_type":"application/x-zip-compressed","embargo_to":"open_access","creator":"swald","checksum":"8c3a1904dceb4bcd04bc9f14b2594bab"}],"publisher":"Institute of Science and Technology Austria","OA_embargo":"6","day":"11","related_material":{"record":[{"id":"14759","status":"public","relation":"part_of_dissertation"}]},"author":[{"full_name":"Wald, Sebastian","last_name":"Wald","orcid":"0000-0002-5869-1604","first_name":"Sebastian","id":"133F200A-B015-11E9-AD41-0EDAE5697425"}],"doi":"10.15479/AT-ISTA-20798","license":"https://creativecommons.org/licenses/by-nc/4.0/","OA_place":"publisher","ddc":["530"],"degree_awarded":"PhD","keyword":["entanglement-enhanced atom interferometry","cavity QED","spin-squeezing","dipole trap","quantum optics"],"status":"public","oa_version":"Published Version","month":"12","date_created":"2025-12-11T11:48:11Z","year":"2025","date_updated":"2026-06-15T22:30:04Z","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-075-6"]},"corr_author":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa":1,"department":[{"_id":"GradSch"},{"_id":"OnHo"}],"supervisor":[{"first_name":"Onur","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2031-204X","last_name":"Hosten","full_name":"Hosten, Onur"}],"date_published":"2025-12-11T00:00:00Z","article_processing_charge":"No","title":"Atoms in a propagating-wave cavity for squeezed Mach-Zehnder atom interferometry","tmp":{"image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"language":[{"iso":"eng"}],"file_date_updated":"2026-06-15T22:30:03Z","has_accepted_license":"1","type":"dissertation","_id":"20798"},{"citation":{"chicago":"Hlavata, Annamaria, Benjamin Neuditschko, Ulla Schellhaas, Clemens Plaschka, Franz Herzog, and Carrie Bernecky. “Structure of Cytoplasmic RNA Polymerase II.” bioRxiv, 2025. <a href=\"https://doi.org/10.64898/2025.12.10.692585\">https://doi.org/10.64898/2025.12.10.692585</a>.","mla":"Hlavata, Annamaria, et al. <i>Structure of Cytoplasmic RNA Polymerase II</i>. bioRxiv, 2025, doi:<a href=\"https://doi.org/10.64898/2025.12.10.692585\">10.64898/2025.12.10.692585</a>.","ista":"Hlavata A, Neuditschko B, Schellhaas U, Plaschka C, Herzog F, Bernecky C. 2025. Structure of cytoplasmic RNA polymerase II. <a href=\"https://doi.org/10.64898/2025.12.10.692585\">10.64898/2025.12.10.692585</a>.","ama":"Hlavata A, Neuditschko B, Schellhaas U, Plaschka C, Herzog F, Bernecky C. Structure of cytoplasmic RNA polymerase II. 2025. doi:<a href=\"https://doi.org/10.64898/2025.12.10.692585\">10.64898/2025.12.10.692585</a>","short":"A. Hlavata, B. Neuditschko, U. Schellhaas, C. Plaschka, F. Herzog, C. Bernecky, (2025).","apa":"Hlavata, A., Neuditschko, B., Schellhaas, U., Plaschka, C., Herzog, F., &#38; Bernecky, C. (2025). Structure of cytoplasmic RNA polymerase II. bioRxiv. <a href=\"https://doi.org/10.64898/2025.12.10.692585\">https://doi.org/10.64898/2025.12.10.692585</a>","ieee":"A. Hlavata, B. Neuditschko, U. Schellhaas, C. Plaschka, F. Herzog, and C. Bernecky, “Structure of cytoplasmic RNA polymerase II.” bioRxiv, 2025."},"acknowledgement":"We thank A. Salmazo for assistance with Pol II purification. We thank staff at the VBCF Proteomics facility for immunoprecipitation-mass spectrometry analysis, and J.A. Stopp for assistance with IP-MS data visualization. This research was further supported by the Scientific Service Units (SSUs) of IST Austria through resources provided by the Lab Support Facility (LSF), Electron Microscopy (EMF), Scientific Computing (SciComp), and the Preclinical Facility (PCF).","date_created":"2025-12-11T13:33:27Z","year":"2025","date_updated":"2025-12-15T09:48:22Z","publication_status":"published","abstract":[{"text":"RNA polymerase II (Pol II) must be assembled in the cytoplasm before it enters the nucleus, where it transcribes protein-coding genes. Although transcription by Pol II is intensively studied, how this central multi-subunit enzyme is made and the role of dedicated factors remains unclear. Here, we report the integrative structural analysis of a native human Pol II from the cytoplasm captured near the end of biogenesis. The complex contained Gdown1 and three biogenesis factors – RPAP2 and the critical small GTPases GPN1 and GPN3. Cryo-EM analysis of the complex revealed how Gdown1 and RPAP2 associate with Pol II and prevent the premature association of transcription factors. Further biochemical and cryo-EM analysis revealed how RPAP2 recruits GPN1–GPN3 to the complex, and how the assembly of the RPAP2–GPN1–GPN3 complex is controlled by GTP hydrolysis. The combined results uncover a network of interactions that chaperone cytoplasmic Pol II to prevent aberrant interactions, reveal a GTP-controlled switch during the final stages of Pol II biogenesis, and suggest a general mechanism for the action of GPN-loop GTPase family of enzymes.","lang":"eng"}],"author":[{"full_name":"Hlavata, Annamaria","last_name":"Hlavata","id":"36062FEC-F248-11E8-B48F-1D18A9856A87","first_name":"Annamaria"},{"first_name":"Benjamin","full_name":"Neuditschko, Benjamin","last_name":"Neuditschko"},{"first_name":"Ulla","full_name":"Schellhaas, Ulla","last_name":"Schellhaas"},{"full_name":"Plaschka, Clemens","last_name":"Plaschka","first_name":"Clemens"},{"first_name":"Franz","last_name":"Herzog","full_name":"Herzog, Franz"},{"full_name":"Bernecky, Carrie A","last_name":"Bernecky","id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","first_name":"Carrie A","orcid":"0000-0003-0893-7036"}],"day":"10","department":[{"_id":"CaBe"}],"publisher":"bioRxiv","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","oa":1,"language":[{"iso":"eng"}],"article_processing_charge":"No","title":"Structure of cytoplasmic RNA polymerase II","doi":"10.64898/2025.12.10.692585","date_published":"2025-12-10T00:00:00Z","month":"12","oa_version":"None","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"EM-Fac"},{"_id":"ScienComp"},{"_id":"PreCl"}],"_id":"20804","type":"preprint","status":"public","main_file_link":[{"url":"https://doi.org/10.64898/2025.12.10.692585","open_access":"1"}]},{"OA_place":"publisher","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","doi":"10.15479/AT-ISTA-20811","month":"12","oa_version":"Published Version","status":"public","degree_awarded":"PhD","ddc":["616","576","614","519"],"citation":{"ama":"Rella S. Adaptive processes in biology and culture : Models of evolving vaccine resistance and the record statistics of innovation. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20811\">10.15479/AT-ISTA-20811</a>","chicago":"Rella, Simon. “Adaptive Processes in Biology and Culture : Models of Evolving Vaccine Resistance and the Record Statistics of Innovation.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20811\">https://doi.org/10.15479/AT-ISTA-20811</a>.","mla":"Rella, Simon. <i>Adaptive Processes in Biology and Culture : Models of Evolving Vaccine Resistance and the Record Statistics of Innovation</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20811\">10.15479/AT-ISTA-20811</a>.","ista":"Rella S. 2025. Adaptive processes in biology and culture : Models of evolving vaccine resistance and the record statistics of innovation. Institute of Science and Technology Austria.","short":"S. Rella, Adaptive Processes in Biology and Culture : Models of Evolving Vaccine Resistance and the Record Statistics of Innovation, Institute of Science and Technology Austria, 2025.","apa":"Rella, S. (2025). <i>Adaptive processes in biology and culture : Models of evolving vaccine resistance and the record statistics of innovation</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20811\">https://doi.org/10.15479/AT-ISTA-20811</a>","ieee":"S. Rella, “Adaptive processes in biology and culture : Models of evolving vaccine resistance and the record statistics of innovation,” Institute of Science and Technology Austria, 2025."},"file":[{"creator":"srella","checksum":"a0bd7a585720e60df284101b8afdf6bb","success":1,"file_name":"2025_Rella_Simon_Thesis.pdf","file_size":29019662,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_updated":"2025-12-16T21:49:52Z","file_id":"20831","date_created":"2025-12-16T21:49:52Z"},{"date_created":"2025-12-16T21:52:19Z","file_id":"20832","date_updated":"2025-12-16T21:52:19Z","content_type":"application/zip","relation":"source_file","file_size":42094025,"access_level":"open_access","file_name":"2025_Rella_Simon_Thesis_Sourcefiles.zip","checksum":"b8b3a90932ae1d96d307838710f46e32","creator":"srella"}],"publication_status":"published","alternative_title":["ISTA Thesis"],"page":"95","author":[{"full_name":"Rella, Simon","last_name":"Rella","id":"B4765ACA-AA38-11E9-AC9A-0930E6697425","first_name":"Simon"}],"day":"15","related_material":{"record":[{"id":"18307","relation":"part_of_dissertation","status":"public"},{"id":"9905","relation":"part_of_dissertation","status":"public"}]},"publisher":"Institute of Science and Technology Austria","language":[{"iso":"eng"}],"file_date_updated":"2025-12-16T21:52:19Z","title":"Adaptive processes in biology and culture : Models of evolving vaccine resistance and the record statistics of innovation","article_processing_charge":"No","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"date_published":"2025-12-15T00:00:00Z","_id":"20811","type":"dissertation","has_accepted_license":"1","publication_identifier":{"issn":["2663-337X"]},"date_created":"2025-12-12T14:39:56Z","date_updated":"2026-04-07T12:34:58Z","year":"2025","abstract":[{"text":"\tThis thesis is organized into two parts, each comprising two chapters: Chapter 1 and 2 offer models for the evolution of vaccine resistance in response to diverse vaccination strategies. Chapter 3 and 4 review the statistics of records, their connection to models of innovation and an application to the cultural evolution of sports.\r\n\tIn chapter 1 we present a modelling study from 2021 on the evolution of SARS-CoV-2. At that time the vaccine-resistant Omicron variant had not yet evolved. In our model we consider a population that is becoming vaccinated over time, while a pathogen is spreading in the population and eventually becoming resistant to the vaccine. We explore effective pharmaceutical and non-pharmaceutical interventions to prevent the emergence of vaccine resistance. \r\n\tIn chapter 2 we model a particular set of complex vaccination strategies, mosaic and pyramid vaccination, where an immunologically diverse portfolio of vaccines is considered. We find that a bet-hatching strategy, in which vaccine types are distributed in the population, is effective at hindering the evolution of vaccine resistance if mutation rates are high. \r\n\tIn chapter 3 we switch gears and present a review on the statistics of records. We highlight similarities and analogies to other models in the fields of statistical physics, evolution and innovation. This offers interesting complimentary perspectives on well-known models. \r\n\tIn chapter 4 we apply models of record statistics and innovation to study cultural evolution in sport. We propose a model of sport evolution that combines deterministic improvements in performance and stochastic bursts of improvements due to innovation. ","lang":"eng"}],"supervisor":[{"last_name":"Tkačik","full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gašper","orcid":"0000-0002-6699-1455"},{"orcid":"0000-0001-8243-4694","first_name":"Fyodor","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","full_name":"Kondrashov, Fyodor","last_name":"Kondrashov"}],"department":[{"_id":"GradSch"},{"_id":"GaTk"},{"_id":"FyKo"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","corr_author":"1","oa":1},{"author":[{"first_name":"Matthias","full_name":"Keller, Matthias","last_name":"Keller"},{"last_name":"Lenz","full_name":"Lenz, Daniel","first_name":"Daniel"},{"first_name":"Marcel","full_name":"Schmidt, Marcel","last_name":"Schmidt"},{"first_name":"Michael","last_name":"Schwarz","full_name":"Schwarz, Michael"},{"orcid":"0000-0002-0519-4241","first_name":"Melchior","id":"88644358-0A0E-11EA-8FA5-49A33DDC885E","full_name":"Wirth, Melchior","last_name":"Wirth"}],"day":"03","publisher":"Springer Nature","project":[{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems"},{"name":"Optimal Transport and Stochastic Dynamics","_id":"256E75B8-B435-11E9-9278-68D0E5697425","grant_number":"716117","call_identifier":"H2020"},{"grant_number":"ESP156_N","_id":"34c6ea2d-11ca-11ed-8bc3-c04f3c502833","name":"Gradient flow techniques for quantum Markov semigroups"}],"volume":64,"citation":{"short":"M. Keller, D. Lenz, M. Schmidt, M. Schwarz, M. Wirth, Potential Analysis 64 (2025).","apa":"Keller, M., Lenz, D., Schmidt, M., Schwarz, M., &#38; Wirth, M. (2025). Boundary representations of intermediate forms between a regular Dirichlet form and its active main part. <i>Potential Analysis</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11118-025-10251-y\">https://doi.org/10.1007/s11118-025-10251-y</a>","mla":"Keller, Matthias, et al. “Boundary Representations of Intermediate Forms between a Regular Dirichlet Form and Its Active Main Part.” <i>Potential Analysis</i>, vol. 64, 6, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s11118-025-10251-y\">10.1007/s11118-025-10251-y</a>.","ama":"Keller M, Lenz D, Schmidt M, Schwarz M, Wirth M. Boundary representations of intermediate forms between a regular Dirichlet form and its active main part. <i>Potential Analysis</i>. 2025;64. doi:<a href=\"https://doi.org/10.1007/s11118-025-10251-y\">10.1007/s11118-025-10251-y</a>","ista":"Keller M, Lenz D, Schmidt M, Schwarz M, Wirth M. 2025. Boundary representations of intermediate forms between a regular Dirichlet form and its active main part. Potential Analysis. 64, 6.","chicago":"Keller, Matthias, Daniel Lenz, Marcel Schmidt, Michael Schwarz, and Melchior Wirth. “Boundary Representations of Intermediate Forms between a Regular Dirichlet Form and Its Active Main Part.” <i>Potential Analysis</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s11118-025-10251-y\">https://doi.org/10.1007/s11118-025-10251-y</a>.","ieee":"M. Keller, D. Lenz, M. Schmidt, M. Schwarz, and M. Wirth, “Boundary representations of intermediate forms between a regular Dirichlet form and its active main part,” <i>Potential Analysis</i>, vol. 64. Springer Nature, 2025."},"publication_status":"epub_ahead","ec_funded":1,"scopus_import":"1","month":"12","article_type":"original","oa_version":"Published Version","status":"public","main_file_link":[{"url":"https://doi.org/10.1007/s11118-025-10251-y","open_access":"1"}],"ddc":["510"],"article_number":"6","OA_place":"publisher","doi":"10.1007/s11118-025-10251-y","quality_controlled":"1","department":[{"_id":"JaMa"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"arxiv":1,"publication_identifier":{"eissn":["1572-929X"],"issn":["0926-2601"]},"acknowledgement":"Open Access funding enabled and organized by Projekt DEAL. The first three authors acknowledge financial support of the DFG within the priority programme Geometry at Infinity.\r\nM.W. acknowledges financial support by the German Academic Scholarship Foundation, by the Austrian Science Fund (FWF) through grant number F65 and the Esprit Programme [ESP 156], and by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 716117).","publication":"Potential Analysis","date_created":"2025-12-14T23:02:03Z","year":"2025","date_updated":"2025-12-15T13:11:24Z","abstract":[{"text":"We characterize all semigroups sandwiched between the semigroup of a Dirichlet form and the semigroup of its active main part. In case the Dirichlet form is regular, we give a more explicit description of the quadratic forms of the sandwiched semigroups in terms of pairs consisting of an open set and a measure on an abstract boundary.","lang":"eng"}],"external_id":{"arxiv":["2301.01035"]},"PlanS_conform":"1","intvolume":"        64","_id":"20814","type":"journal_article","has_accepted_license":"1","OA_type":"hybrid","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","title":"Boundary representations of intermediate forms between a regular Dirichlet form and its active main part","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_published":"2025-12-03T00:00:00Z"},{"department":[{"_id":"MaRo"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"date_created":"2025-12-14T23:02:04Z","publication":"Genome Biology","year":"2025","date_updated":"2025-12-15T13:19:41Z","publication_identifier":{"eissn":["1474-760X"],"issn":["1474-7596"]},"acknowledgement":"Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006] and is currently supported by the Wellcome Trust [216767/Z/19/Z]. Genotyping of the Generation Scotland samples was carried out by the Genetics Core Laboratory at the Edinburgh Clinical Research Facility, University of Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” (STRADL) Reference 104036/Z/14/Z). The DNA methylation profiling and analysis was supported by Wellcome Investigator Award 220857/Z/20/Z and Grant 104036/Z/14/Z (PI: Prof AM McIntosh) and through funding from NARSAD (Ref: 27404; awardee: Dr DM Howard) and the Royal College of Physicians of Edinburgh (Sim Fellowship; Awardee: Prof HC Whalley).\r\nJAR is a University of Edinburgh Clinical Academic Track PhD student, supported by the Wellcome Trust (319878/Z/24/Z). ADC was supported by a Medical Research Council PhD Studentship in Precision Medicine with funding from the Medical Research Council Doctoral Training Program and the University of Edinburgh College of Medicine and Veterinary Medicine. HMS is a student on the University of Edinburgh Translational Neuroscience PhD programme funded by the Wellcome Trust (218493/Z/19/Z). CH was funded by MRC Human Genetics Unit program (QTL in Health and Disease) (grant U.MC_UU_00007/10). S.R.C. is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (221890/Z/20/Z). JM and REM were supported by Alzheimer’s Society project grant AS-PG-19b-010.","external_id":{"pmid":["41361833"]},"abstract":[{"lang":"eng","text":"Background: DNA methylation (DNAm) can regulate gene expression, and its genome-wide patterns (epigenetic scores or EpiScores) can act as biomarkers for complex traits. The relative stability of methylation profiles may enable better assessment of chronic exposures compared to single time-point protein measures. We present the first large-scale epigenetic study of the highly-abundant serum proteome measured via ultra-high throughput mass spectrometry in 14,671 samples from the Generation Scotland cohort. We further demonstrate the first large-scale comparison of protein EpiScores and their respective proteins as predictors of incident cardiovascular disease.\r\n\r\nResults: Marginal epigenome-wide association models, adjusting for age, sex, measurement batch, estimated white cell proportions, BMI, smoking and methylation principal components, reveal 15,855 significant CpG – protein associations across 125 of 133 proteins PBonferroni < 2.71 × 10-10. Bayesian epigenome-wide association studies of the same 133 proteins reveal 697 CpG-Protein associations (posterior inclusion probability > 0.95). 112 protein EpiScores correlate significantly with their respective protein in a holdout test-set. Of these, sixteen associate significantly with incident all-cause cardiovascular disease (Nevents=191) compared to one measured protein.\r\n\r\nConclusions: We highlight a complex interplay between the blood-based methylome and proteome. Importantly, we show that protein EpiScores correlate with measured proteins and demonstrate that the, as-yet understudied, high-abundance proteome may yield clinically relevant biomarkers. The protein EpiScores demonstrate more significant associations with cardiovascular disease than directly measured proteins, suggesting their potential as clinical biomarkers for monitoring or predicting disease risk. We suggest that biomarker development could be enhanced by the consideration of protein EpiScores alongside measured proteins."}],"intvolume":"        26","has_accepted_license":"1","_id":"20816","type":"journal_article","file_date_updated":"2025-12-15T13:18:07Z","language":[{"iso":"eng"}],"OA_type":"gold","pmid":1,"date_published":"2025-12-08T00:00:00Z","title":"Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants","article_processing_charge":"Yes","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"day":"08","author":[{"first_name":"Josephine A.","last_name":"Robertson","full_name":"Robertson, Josephine A."},{"first_name":"Jakub","id":"b995e25b-8c4b-11ed-a6d8-f71b7bcd6122","last_name":"Bajzik","full_name":"Bajzik, Jakub"},{"full_name":"Vernardis, Spyros","last_name":"Vernardis","first_name":"Spyros"},{"first_name":"Aleksandra D.","full_name":"Chybowska, Aleksandra D.","last_name":"Chybowska"},{"full_name":"Mccartney, Daniel L.","last_name":"Mccartney","first_name":"Daniel L."},{"first_name":"Arturas","full_name":"Grauslys, Arturas","last_name":"Grauslys"},{"last_name":"Mur","full_name":"Mur, Jure","first_name":"Jure"},{"last_name":"Smith","full_name":"Smith, Hannah M.","first_name":"Hannah M."},{"full_name":"Campbell, Archie","last_name":"Campbell","first_name":"Archie"},{"full_name":"Drake, Camilla","last_name":"Drake","first_name":"Camilla"},{"first_name":"Hannah","last_name":"Grant","full_name":"Grant, Hannah"},{"full_name":"Pearce, Jamie","last_name":"Pearce","first_name":"Jamie"},{"last_name":"Russ","full_name":"Russ, Tom C.","first_name":"Tom C."},{"last_name":"Adkin","full_name":"Adkin, Poppy","first_name":"Poppy"},{"last_name":"White","full_name":"White, Matthew","first_name":"Matthew"},{"full_name":"Brigden, Charles","last_name":"Brigden","first_name":"Charles"},{"full_name":"Messner, Christoph B.","last_name":"Messner","first_name":"Christoph B."},{"full_name":"Porteous, David J.","last_name":"Porteous","first_name":"David J."},{"first_name":"Caroline","last_name":"Hayward","full_name":"Hayward, Caroline"},{"first_name":"Simon R.","last_name":"Cox","full_name":"Cox, Simon R."},{"first_name":"Aleksej","last_name":"Zelezniak","full_name":"Zelezniak, Aleksej"},{"last_name":"Ralser","full_name":"Ralser, Markus","first_name":"Markus"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","first_name":"Matthew Richard","orcid":"0000-0001-8982-8813","last_name":"Robinson","full_name":"Robinson, Matthew Richard"},{"last_name":"Marioni","full_name":"Marioni, Riccardo E.","first_name":"Riccardo E."}],"volume":26,"publisher":"Springer Nature","publication_status":"published","file":[{"content_type":"application/pdf","file_id":"20825","date_updated":"2025-12-15T13:18:07Z","date_created":"2025-12-15T13:18:07Z","file_name":"2025_GenomeBiology_Robertson.pdf","file_size":2206991,"access_level":"open_access","relation":"main_file","checksum":"7c92919af1b5820d01e91e08906a411f","success":1,"creator":"dernst"}],"citation":{"ama":"Robertson JA, Bajzik J, Vernardis S, et al. Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. <i>Genome Biology</i>. 2025;26. doi:<a href=\"https://doi.org/10.1186/s13059-025-03892-0\">10.1186/s13059-025-03892-0</a>","mla":"Robertson, Josephine A., et al. “Methylome-Wide Association Studies and Epigenetic Biomarker Development for 133 Mass Spectrometry-Assessed Circulating Proteins in 14,671 Generation Scotland Participants.” <i>Genome Biology</i>, vol. 26, 417, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1186/s13059-025-03892-0\">10.1186/s13059-025-03892-0</a>.","chicago":"Robertson, Josephine A., Jakub Bajzik, Spyros Vernardis, Aleksandra D. Chybowska, Daniel L. Mccartney, Arturas Grauslys, Jure Mur, et al. “Methylome-Wide Association Studies and Epigenetic Biomarker Development for 133 Mass Spectrometry-Assessed Circulating Proteins in 14,671 Generation Scotland Participants.” <i>Genome Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1186/s13059-025-03892-0\">https://doi.org/10.1186/s13059-025-03892-0</a>.","ista":"Robertson JA, Bajzik J, Vernardis S, Chybowska AD, Mccartney DL, Grauslys A, Mur J, Smith HM, Campbell A, Drake C, Grant H, Pearce J, Russ TC, Adkin P, White M, Brigden C, Messner CB, Porteous DJ, Hayward C, Cox SR, Zelezniak A, Ralser M, Robinson MR, Marioni RE. 2025. Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. Genome Biology. 26, 417.","short":"J.A. Robertson, J. Bajzik, S. Vernardis, A.D. Chybowska, D.L. Mccartney, A. Grauslys, J. Mur, H.M. Smith, A. Campbell, C. Drake, H. Grant, J. Pearce, T.C. Russ, P. Adkin, M. White, C. Brigden, C.B. Messner, D.J. Porteous, C. Hayward, S.R. Cox, A. Zelezniak, M. Ralser, M.R. Robinson, R.E. Marioni, Genome Biology 26 (2025).","apa":"Robertson, J. A., Bajzik, J., Vernardis, S., Chybowska, A. D., Mccartney, D. L., Grauslys, A., … Marioni, R. E. (2025). Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. <i>Genome Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s13059-025-03892-0\">https://doi.org/10.1186/s13059-025-03892-0</a>","ieee":"J. A. Robertson <i>et al.</i>, “Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants,” <i>Genome Biology</i>, vol. 26. Springer Nature, 2025."},"DOAJ_listed":"1","scopus_import":"1","oa_version":"Published Version","month":"12","article_type":"original","ddc":["570"],"article_number":"417","status":"public","OA_place":"publisher","quality_controlled":"1","doi":"10.1186/s13059-025-03892-0"},{"publisher":"ML Research Press","project":[{"call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"volume":267,"author":[{"last_name":"Pervez","full_name":"Pervez, Adeel A","id":"fca6d90c-d47f-11ee-bc87-93ff51604981","first_name":"Adeel A"},{"first_name":"Efstratios","full_name":"Gavves, Efstratios","last_name":"Gavves"},{"last_name":"Locatello","full_name":"Locatello, Francesco","orcid":"0000-0002-4850-0683","first_name":"Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4"}],"related_material":{"link":[{"relation":"software","url":"https://github.com/ alpz/mech-nn-discovery-pde"}]},"day":"01","ec_funded":1,"scopus_import":"1","citation":{"short":"A.A. Pervez, E. Gavves, F. Locatello, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 48962–48973.","apa":"Pervez, A. A., Gavves, E., &#38; Locatello, F. (2025). Mechanistic PDE networks for discovery of governing equations. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 48962–48973). Vancouver, Canada: ML Research Press.","mla":"Pervez, Adeel A., et al. “Mechanistic PDE Networks for Discovery of Governing Equations.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 48962–73.","ama":"Pervez AA, Gavves E, Locatello F. Mechanistic PDE networks for discovery of governing equations. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:48962-48973.","chicago":"Pervez, Adeel A, Efstratios Gavves, and Francesco Locatello. “Mechanistic PDE Networks for Discovery of Governing Equations.” In <i>42nd International Conference on Machine Learning</i>, 267:48962–73. ML Research Press, 2025.","ista":"Pervez AA, Gavves E, Locatello F. 2025. Mechanistic PDE networks for discovery of governing equations. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 48962–48973.","ieee":"A. A. Pervez, E. Gavves, and F. Locatello, “Mechanistic PDE networks for discovery of governing equations,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 48962–48973."},"file":[{"access_level":"open_access","relation":"main_file","file_size":993381,"file_name":"2025_ICML_Pervez.pdf","date_updated":"2025-12-16T12:21:49Z","file_id":"20827","date_created":"2025-12-16T12:21:49Z","content_type":"application/pdf","creator":"dernst","success":1,"checksum":"933cb673fb41416f537278fb990df6c3"}],"publication_status":"published","alternative_title":["PMLR"],"page":"48962-48973","status":"public","ddc":["000"],"month":"05","oa_version":"Published Version","conference":{"location":"Vancouver, Canada","end_date":"2025-07-19","start_date":"2025-07-13","name":"ICML: International Conference on Machine Learning"},"quality_controlled":"1","OA_place":"publisher","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","department":[{"_id":"FrLo"}],"abstract":[{"lang":"eng","text":"We present Mechanistic PDE Networks -- a model for discovery of governing partial differential equations from data. Mechanistic PDE Networks represent spatiotemporal data as space-time dependent linear partial differential equations in neural network hidden representations. The represented PDEs are then solved and decoded for specific tasks. The learned PDE representations naturally express the spatiotemporal dynamics in data in neural network hidden space, enabling increased modeling power. Solving the PDE representations in a compute and memory-efficient way, however, is a significant challenge. We develop a native, GPU-capable, parallel, sparse and differentiable multigrid solver specialized for linear partial differential equations that acts as a module in Mechanistic PDE Networks. Leveraging the PDE solver we propose a discovery architecture that can discovers nonlinear PDEs in complex settings, while being robust to noise. We validate PDE discovery on a number of PDEs including reaction-diffusion and Navier-Stokes equations."}],"external_id":{"arxiv":["2502.18377"]},"acknowledgement":"AP. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.\r\nFL. This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/COE12. For open access purposes, the author has applied a CC BY public\r\ncopyright license to any author accepted manuscript version arising from this submission.","publication_identifier":{"eissn":["2640-3498"]},"arxiv":1,"year":"2025","date_updated":"2025-12-16T12:24:55Z","date_created":"2025-12-14T23:02:04Z","publication":"42nd International Conference on Machine Learning","_id":"20817","type":"conference","has_accepted_license":"1","intvolume":"       267","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_processing_charge":"No","title":"Mechanistic PDE networks for discovery of governing equations","date_published":"2025-05-01T00:00:00Z","OA_type":"gold","file_date_updated":"2025-12-16T12:21:49Z","language":[{"iso":"eng"}]},{"type":"journal_article","_id":"20818","OA_type":"closed access","language":[{"iso":"eng"}],"article_processing_charge":"No","title":"The miniW domain directs polarized membrane localization of non-canonical PINs in Marchantia polymorpha","date_published":"2025-12-03T00:00:00Z","pmid":1,"department":[{"_id":"JiFr"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"The authors sincerely thank Dr. Shutang Tan for experimental support and Dr. Barbara Kloeckener Gruissem for critical reading and constructive advice on the manuscript. This study was supported by the European Research Council Advanced Grant (ETAP-742985 to H.T. and J.F.), by the Ministry of Science and Technology (grant 112-2636-B-005-001- to K.-J.L.), and by the Ministry of Education (grant MOE-109-YSFAG-0006-001-P1 to K.-J.L.).","publication_identifier":{"eissn":["1365-3040"],"issn":["0140-7791"]},"date_updated":"2025-12-15T13:56:26Z","year":"2025","date_created":"2025-12-14T23:02:05Z","publication":"Plant Cell and Environment","abstract":[{"lang":"eng","text":"This study demonstrates that Marchantia non-canonical PINs are predominantly localized to the plasma membrane, with MpPINX and MpPINW exhibiting asymmetric distribution.\r\nA newly identified miniW domain within the MpPINW hydrophilic loop governs subcellular trafficking and asymmetric PM localization of non-canonical PINs in Marchantia."}],"external_id":{"pmid":["41340422"]},"article_type":"comment","month":"12","oa_version":"None","status":"public","quality_controlled":"1","doi":"10.1111/pce.70295","author":[{"id":"19BDF720-25A0-11EA-AC6E-928F3DDC885E","first_name":"Han","orcid":"0000-0001-6152-6637","last_name":"Tang","full_name":"Tang, Han"},{"last_name":"Smoljan","full_name":"Smoljan, Adrijana","first_name":"Adrijana","id":"cced8a85-223e-11ed-af04-b0596c55053b"},{"id":"5c243f41-03f3-11ec-841c-96faf48a7ef9","first_name":"Minxia","full_name":"Zou, Minxia","last_name":"Zou"},{"last_name":"Zhang","full_name":"Zhang, Yuzhou","id":"3B6137F2-F248-11E8-B48F-1D18A9856A87","first_name":"Yuzhou","orcid":"0000-0003-2627-6956"},{"first_name":"Kuan Ju","full_name":"Lu, Kuan Ju","last_name":"Lu"},{"full_name":"Friml, Jiří","last_name":"Friml","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří"}],"day":"03","publisher":"Wiley","project":[{"name":"Tracing Evolution of Auxin Transport and Polarity in Plants","call_identifier":"H2020","grant_number":"742985","_id":"261099A6-B435-11E9-9278-68D0E5697425"}],"citation":{"chicago":"Tang, Han, Adrijana Smoljan, Minxia Zou, Yuzhou Zhang, Kuan Ju Lu, and Jiří Friml. “The MiniW Domain Directs Polarized Membrane Localization of Non-Canonical PINs in Marchantia Polymorpha.” <i>Plant Cell and Environment</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/pce.70295\">https://doi.org/10.1111/pce.70295</a>.","mla":"Tang, Han, et al. “The MiniW Domain Directs Polarized Membrane Localization of Non-Canonical PINs in Marchantia Polymorpha.” <i>Plant Cell and Environment</i>, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/pce.70295\">10.1111/pce.70295</a>.","ista":"Tang H, Smoljan A, Zou M, Zhang Y, Lu KJ, Friml J. 2025. The miniW domain directs polarized membrane localization of non-canonical PINs in Marchantia polymorpha. Plant Cell and Environment.","ama":"Tang H, Smoljan A, Zou M, Zhang Y, Lu KJ, Friml J. The miniW domain directs polarized membrane localization of non-canonical PINs in Marchantia polymorpha. <i>Plant Cell and Environment</i>. 2025. doi:<a href=\"https://doi.org/10.1111/pce.70295\">10.1111/pce.70295</a>","short":"H. Tang, A. Smoljan, M. Zou, Y. Zhang, K.J. Lu, J. Friml, Plant Cell and Environment (2025).","apa":"Tang, H., Smoljan, A., Zou, M., Zhang, Y., Lu, K. J., &#38; Friml, J. (2025). The miniW domain directs polarized membrane localization of non-canonical PINs in Marchantia polymorpha. <i>Plant Cell and Environment</i>. Wiley. <a href=\"https://doi.org/10.1111/pce.70295\">https://doi.org/10.1111/pce.70295</a>","ieee":"H. Tang, A. Smoljan, M. Zou, Y. Zhang, K. J. Lu, and J. Friml, “The miniW domain directs polarized membrane localization of non-canonical PINs in Marchantia polymorpha,” <i>Plant Cell and Environment</i>. Wiley, 2025."},"publication_status":"epub_ahead","ec_funded":1,"scopus_import":"1"},{"type":"conference","_id":"20819","acknowledged_ssus":[{"_id":"ScienComp"}],"has_accepted_license":"1","intvolume":"       267","article_processing_charge":"No","title":"Differentially private federated k-means clustering with server-side data","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_published":"2025-05-01T00:00:00Z","OA_type":"gold","language":[{"iso":"eng"}],"file_date_updated":"2025-12-16T12:38:29Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","oa":1,"department":[{"_id":"ChLa"},{"_id":"MoHe"}],"abstract":[{"lang":"eng","text":"Clustering is a cornerstone of data analysis that is particularly suited to identifying coherent subgroups or substructures in unlabeled data, as are generated continuously in large amounts these days. However, in many cases traditional clustering methods are not applicable, because data are increasingly being produced and stored in a distributed way, e.g. on edge devices, and privacy concerns prevent it from being transferred to a central server. To address this challenge, we present FedDP-KMeans, a new algorithm for \r\n-means clustering that is fully-federated as well as differentially private. Our approach leverages (potentially small and out-of-distribution) server-side data to overcome the primary challenge of differentially private clustering methods: the need for a good initialization. Combining our initialization with a simple federated DP-Lloyds algorithm we obtain an algorithm that achieves excellent results on synthetic and real-world benchmark tasks. We also provide a theoretical analysis of our method that provides bounds on the convergence speed and cluster identification success."}],"external_id":{"arxiv":["2506.05408"]},"publication_identifier":{"eissn":["2640-3498"]},"arxiv":1,"acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF) [10.55776/COE12] and supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).\r\n","date_created":"2025-12-14T23:02:05Z","publication":"42nd International Conference on Machine Learning","date_updated":"2026-04-07T11:46:11Z","year":"2025","status":"public","ddc":["000"],"month":"05","oa_version":"Published Version","conference":{"name":"ICML: International Conference on Machine Learning","start_date":"2025-07-13","end_date":"2025-07-19","location":"Vancouver, Canada"},"quality_controlled":"1","OA_place":"publisher","publisher":"ML Research Press","volume":267,"author":[{"full_name":"Scott, Jonathan A","last_name":"Scott","first_name":"Jonathan A","id":"e499926b-f6e0-11ea-865d-9c63db0031e8"},{"id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph","orcid":"0000-0001-8622-7887","full_name":"Lampert, Christoph","last_name":"Lampert"},{"first_name":"David","id":"f8e48cf0-b0ff-11ed-b0e9-b4c35598f964","last_name":"Saulpic","full_name":"Saulpic, David"}],"day":"01","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"21198"}]},"scopus_import":"1","file":[{"creator":"dernst","checksum":"815b32b463023ca21e569c2158745c15","success":1,"file_name":"2025_ICML_Scott.pdf","file_size":746612,"relation":"main_file","access_level":"open_access","content_type":"application/pdf","date_created":"2025-12-16T12:38:29Z","date_updated":"2025-12-16T12:38:29Z","file_id":"20829"}],"citation":{"ieee":"J. A. Scott, C. Lampert, and D. Saulpic, “Differentially private federated k-means clustering with server-side data,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 53757–53790.","chicago":"Scott, Jonathan A, Christoph Lampert, and David Saulpic. “Differentially Private Federated K-Means Clustering with Server-Side Data.” In <i>42nd International Conference on Machine Learning</i>, 267:53757–90. ML Research Press, 2025.","ama":"Scott JA, Lampert C, Saulpic D. Differentially private federated k-means clustering with server-side data. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:53757-53790.","ista":"Scott JA, Lampert C, Saulpic D. 2025. Differentially private federated k-means clustering with server-side data. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 53757–53790.","mla":"Scott, Jonathan A., et al. “Differentially Private Federated K-Means Clustering with Server-Side Data.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 53757–90.","apa":"Scott, J. A., Lampert, C., &#38; Saulpic, D. (2025). Differentially private federated k-means clustering with server-side data. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 53757–53790). Vancouver, Canada: ML Research Press.","short":"J.A. Scott, C. Lampert, D. Saulpic, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 53757–53790."},"publication_status":"published","page":"53757-53790","alternative_title":["PMLR"]},{"ec_funded":1,"scopus_import":"1","citation":{"short":"S. Hensel, T. Laux, Journal of Differential Geometry 130 (2025) 209–268.","apa":"Hensel, S., &#38; Laux, T. (2025). A new varifold solution concept for mean curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness. <i>Journal of Differential Geometry</i>. International Press. <a href=\"https://doi.org/10.4310/jdg/1747065796\">https://doi.org/10.4310/jdg/1747065796</a>","ista":"Hensel S, Laux T. 2025. A new varifold solution concept for mean curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness. Journal of Differential Geometry. 130, 209–268.","mla":"Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for Mean Curvature Flow: Convergence of  the Allen-Cahn Equation and Weak-Strong Uniqueness.” <i>Journal of Differential Geometry</i>, vol. 130, International Press, 2025, pp. 209–68, doi:<a href=\"https://doi.org/10.4310/jdg/1747065796\">10.4310/jdg/1747065796</a>.","chicago":"Hensel, Sebastian, and Tim Laux. “A New Varifold Solution Concept for Mean Curvature Flow: Convergence of  the Allen-Cahn Equation and Weak-Strong Uniqueness.” <i>Journal of Differential Geometry</i>. International Press, 2025. <a href=\"https://doi.org/10.4310/jdg/1747065796\">https://doi.org/10.4310/jdg/1747065796</a>.","ama":"Hensel S, Laux T. A new varifold solution concept for mean curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness. <i>Journal of Differential Geometry</i>. 2025;130:209-268. doi:<a href=\"https://doi.org/10.4310/jdg/1747065796\">10.4310/jdg/1747065796</a>","ieee":"S. Hensel and T. Laux, “A new varifold solution concept for mean curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness,” <i>Journal of Differential Geometry</i>, vol. 130. International Press, pp. 209–268, 2025."},"publication_status":"published","page":"209-268","publisher":"International Press","project":[{"name":"Bridging Scales in Random Materials","grant_number":"948819","call_identifier":"H2020","_id":"0aa76401-070f-11eb-9043-b5bb049fa26d"}],"volume":130,"author":[{"id":"4D23B7DA-F248-11E8-B48F-1D18A9856A87","first_name":"Sebastian","orcid":"0000-0001-7252-8072","full_name":"Hensel, Sebastian","last_name":"Hensel"},{"full_name":"Laux, Tim","last_name":"Laux","first_name":"Tim"}],"day":"01","quality_controlled":"1","doi":"10.4310/jdg/1747065796","OA_place":"repository","main_file_link":[{"url":"https://arxiv.org/abs/2109.04233","open_access":"1"}],"status":"public","keyword":["Mean curvature flow","gradient flows","varifolds","weak solutions","weak-strong uniqueness","calibrated geometry","gradient-flow calibrations"],"article_type":"original","month":"05","oa_version":"Preprint","abstract":[{"text":"We propose a new weak solution concept for (two-phase) mean curvature flow which enjoys both (unconditional) existence and (weak-strong) uniqueness properties. These solutions are evolving varifolds, just as in Brakke's formulation, but are coupled to the phase volumes by a simple transport equation. First, we show that, in the exact same setup as in Ilmanen's proof [J. Differential Geom. 38, 417-461, (1993)], any limit point of solutions to the Allen-Cahn equation is a varifold solution in our sense. Second, we prove that any calibrated flow in the sense of Fischer et al. [arXiv:2003.05478] - and hence any classical solution to mean curvature flow-is unique in the class of our new varifold solutions. This is in sharp contrast to the case of Brakke flows, which a priori may disappear at any given time and are therefore fatally non-unique. Finally, we propose an extension of the solution concept to the multi-phase case which is at least guaranteed to satisfy a weak-strong uniqueness principle.","lang":"eng"}],"external_id":{"arxiv":["2109.04233"]},"acknowledgement":"This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 948819), and from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC-2047/1 – 390685813. The content of this paper was developed and parts of it were written during a visit of the first author to the Hausdorff Center of Mathematics (HCM), University of Bonn. The hospitality and the support of HCM are gratefully acknowledged.","publication_identifier":{"eissn":["1945-743X"],"issn":["0022-040X"]},"arxiv":1,"date_updated":"2025-05-28T09:27:05Z","year":"2025","publication":"Journal of Differential Geometry","date_created":"2021-09-13T12:17:10Z","oa":1,"corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"JuFi"}],"title":"A new varifold solution concept for mean curvature flow: Convergence of  the Allen-Cahn equation and weak-strong uniqueness","article_processing_charge":"No","date_published":"2025-05-01T00:00:00Z","OA_type":"green","language":[{"iso":"eng"}],"_id":"10011","type":"journal_article","intvolume":"       130"},{"external_id":{"isi":["001176563300001"],"arxiv":["2109.10203"]},"abstract":[{"text":"Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem}, denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai: if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed a theory of discrete convex functions on orientable modular graphs generalizing several known classes of functions in discrete convex analysis, such as L♮-convex functions. We consider a more general version of the problem in which unary functions fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where set F⊆(V2) is fixed. We extend the complexity classification above by providing an explicit condition on (μ,F) for the problem to be tractable. In order to prove the tractability part, we generalize Hirai's theory and define a larger class of discrete convex functions. It covers, in particular, another well-known class of functions, namely submodular functions on an integer lattice. Finally, we improve the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n","lang":"eng"}],"publication":"Mathematical Programming","date_created":"2021-09-27T10:48:23Z","date_updated":"2025-05-19T13:52:10Z","year":"2025","publication_identifier":{"eissn":["1436-4646"],"issn":["0025-5610"]},"arxiv":1,"acknowledgement":"We thank the anonymous reviewers for their careful reading of our manuscript and their many insightful comments and suggestions. Open access funding provided by Institute of Science and Technology (IST Austria).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","oa":1,"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"date_published":"2025-01-01T00:00:00Z","title":"Generalized minimum 0-extension problem and discrete convexity","article_processing_charge":"Yes (via OA deal)","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"file_date_updated":"2025-04-16T09:36:08Z","language":[{"iso":"eng"}],"OA_type":"hybrid","has_accepted_license":"1","type":"journal_article","_id":"10045","intvolume":"       209","scopus_import":"1","publication_status":"published","page":"279-322","file":[{"content_type":"application/pdf","date_updated":"2025-04-16T09:36:08Z","file_id":"19578","date_created":"2025-04-16T09:36:08Z","file_name":"2025_MathProgramming_Dvorak.pdf","relation":"main_file","file_size":839510,"access_level":"open_access","checksum":"25d9bd490719b45eca84f4d93a06c69f","success":1,"creator":"dernst"}],"citation":{"ieee":"M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and discrete convexity,” <i>Mathematical Programming</i>, vol. 209. Springer Nature, pp. 279–322, 2025.","apa":"Dvorak, M., &#38; Kolmogorov, V. (2025). Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>","short":"M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322.","ama":"Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. 2025;209:279-322. doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>","chicago":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>.","mla":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>, vol. 209, Springer Nature, 2025, pp. 279–322, doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>.","ista":"Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and discrete convexity. Mathematical Programming. 209, 279–322."},"isi":1,"volume":209,"publisher":"Springer Nature","day":"01","author":[{"last_name":"Dvorak","full_name":"Dvorak, Martin","first_name":"Martin","id":"40ED02A8-C8B4-11E9-A9C0-453BE6697425","orcid":"0000-0001-5293-214X"},{"id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov","full_name":"Kolmogorov, Vladimir"}],"doi":"10.1007/s10107-024-02064-5","quality_controlled":"1","OA_place":"publisher","ddc":["004"],"keyword":["minimum 0-extension problem","metric labeling problem","discrete metric spaces","metric extensions","computational complexity","valued constraint satisfaction problems","discrete convex analysis","L-convex functions"],"status":"public","oa_version":"Published Version","month":"01","article_type":"original"},{"type":"journal_article","_id":"17240","has_accepted_license":"1","intvolume":"        26","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_processing_charge":"Yes (via OA deal)","title":"Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion","date_published":"2025-01-01T00:00:00Z","pmid":1,"OA_type":"hybrid","language":[{"iso":"eng"}],"file_date_updated":"2025-08-05T11:42:27Z","oa":1,"corr_author":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","department":[{"_id":"RoSe"}],"abstract":[{"lang":"eng","text":"We prove an upper bound on the energy density of the dilute spin-\\(\\frac {1}{2}\\) Fermi gas capturing the leading correction to the kinetic energy\\(8\\pi a\\rho _\\uparrow\\rho _\\downarrow\\) with an error of size smaller than\\(a\\rho^{2}(a^ 3\\rho)^{1/3-\\varepsilon}\\) for any\\(\\varepsilon> 0\\), where a denotes the scattering length of the interaction. The result is valid for a large class of interactions including interactions with a hard core. A central ingredient in the proof is a rigorous version of a fermionic cluster expansion adapted from the formal expansion of Gaudin et al. (Nucl Phys A 176(2):237–260, 1971. https://doi.org/10.1016/0375-9474(71)90267-3)."}],"external_id":{"isi":["001261197700002"],"pmid":["39926012"]},"PlanS_conform":"1","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).\r\nWe thank Alessandro Giuliani and Robert Seiringer for helpful discussions and Robert Seiringer for his comments on the manuscript. Financial support by the Austrian Science Fund (FWF) through Grant https://doi.org/10.55776/I6427 (as part of the SFB/TRR 352) is gratefully acknowledged.","publication_identifier":{"issn":["1424-0637"]},"year":"2025","date_updated":"2026-04-07T13:01:40Z","date_created":"2024-07-14T22:01:12Z","publication":"Annales Henri Poincare","status":"public","ddc":["510"],"article_type":"original","month":"01","oa_version":"Published Version","quality_controlled":"1","doi":"10.1007/s00023-024-01450-1","OA_place":"publisher","project":[{"name":"Mathematical Challenges in BCS Theory of Superconductivity","grant_number":"I06427","_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b"}],"publisher":"Springer Nature","volume":26,"author":[{"last_name":"Lauritsen","full_name":"Lauritsen, Asbjørn Bækgaard","first_name":"Asbjørn Bækgaard","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","orcid":"0000-0003-4476-2288"}],"related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"18135"}]},"day":"01","scopus_import":"1","file":[{"checksum":"01b6572f55f721e97498522c85072ed2","success":1,"creator":"dernst","content_type":"application/pdf","file_id":"20125","date_updated":"2025-08-05T11:42:27Z","date_created":"2025-08-05T11:42:27Z","file_name":"2025_AnnalesHenriPoincare_Lauritsen.pdf","access_level":"open_access","file_size":797241,"relation":"main_file"}],"citation":{"short":"A.B. Lauritsen, Annales Henri Poincare 26 (2025) 203–243.","apa":"Lauritsen, A. B. (2025). Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. <i>Annales Henri Poincare</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00023-024-01450-1\">https://doi.org/10.1007/s00023-024-01450-1</a>","mla":"Lauritsen, Asbjørn Bækgaard. “Almost Optimal Upper Bound for the Ground State Energy of a Dilute Fermi Gas via Cluster Expansion.” <i>Annales Henri Poincare</i>, vol. 26, Springer Nature, 2025, pp. 203–43, doi:<a href=\"https://doi.org/10.1007/s00023-024-01450-1\">10.1007/s00023-024-01450-1</a>.","ama":"Lauritsen AB. Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. <i>Annales Henri Poincare</i>. 2025;26:203-243. doi:<a href=\"https://doi.org/10.1007/s00023-024-01450-1\">10.1007/s00023-024-01450-1</a>","chicago":"Lauritsen, Asbjørn Bækgaard. “Almost Optimal Upper Bound for the Ground State Energy of a Dilute Fermi Gas via Cluster Expansion.” <i>Annales Henri Poincare</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00023-024-01450-1\">https://doi.org/10.1007/s00023-024-01450-1</a>.","ista":"Lauritsen AB. 2025. Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. Annales Henri Poincare. 26, 203–243.","ieee":"A. B. Lauritsen, “Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion,” <i>Annales Henri Poincare</i>, vol. 26. Springer Nature, pp. 203–243, 2025."},"isi":1,"publication_status":"published","page":"203-243"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"department":[{"_id":"RySh"}],"external_id":{"pmid":["38887180"],"isi":["001250034200001"]},"abstract":[{"text":"Voltage-gated CaV2.1 (P/Q-type) Ca2+ channels play a crucial role in regulating neurotransmitter release, thus contributing to synaptic plasticity and to processes such as learning and memory. Despite their recognized importance in neural function, there is limited information on their potential involvement in neurodegenerative conditions such as Alzheimer's disease (AD). Here, we aimed to explore the impact of AD pathology on the density and nanoscale compartmentalization of CaV2.1 channels in the hippocampus in association with GABAB receptors. Histoblotting experiments showed that the density of CaV2.1 channel was significantly reduced in the hippocampus of APP/PS1 mice in a laminar-dependent manner. CaV2.1 channel was enriched in the active zone of the axon terminals and was present at a very low density over the surface of dendritic tree of the CA1 pyramidal cells, as shown by quantitative SDS-digested freeze-fracture replica labelling (SDS-FRL). In APP/PS1 mice, the density of CaV2.1 channel in the active zone was significantly reduced in the strata radiatum and lacunosum-moleculare, while it remained unaltered in the stratum oriens. The decline in Cav2.1 channel density was found to be associated with a corresponding impairment in the GABAergic synaptic function, as evidenced by electrophysiological experiments carried out in the hippocampus of APP/PS1 mice. Remarkably, double SDS-FRL showed a co-clustering of CaV2.1 channel and GABAB1 receptor in nanodomains (~40–50 nm) in wild type mice, while in APP/PS1 mice this nanoarchitecture was absent. Together, these findings suggest that the AD pathology-induced reduction in CaV2.1 channel density and CaV2.1-GABAB1 de-clustering may play a role in the synaptic transmission alterations shown in the AD hippocampus. Therefore, uncovering these layer-dependent changes in P/Q calcium currents associated with AD pathology can benefit the development of future strategies for AD management.","lang":"eng"}],"date_created":"2024-07-22T07:48:20Z","publication":"Brain Pathology","date_updated":"2025-05-19T13:58:12Z","year":"2025","publication_identifier":{"eissn":["1750-3639"],"issn":["1015-6305"]},"acknowledgement":"Funding sources were Spanish Ministerio de Economía y Competitividad, Junta de Comunidades de Castilla-La Mancha (Spain), Life Science Innovation Center at University of Fukui and German Research Foundation.\r\nGrants RTI2018-095812-B-I00 and PID2021-125875OB-I00 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe” to Rafael Luján. This study was also supported by a grant from Junta de Comunidades de Castilla-La Mancha (SBPLY/17/180501/000229 and SBPLY/21/180501/000064) and Universidad de Castilla-La Mancha (2023-GRIN-34187) to Rafael Luján, and Life Science Innovation Center (Research and Education Program for Life Science) at University of Fukui and JSPS KAKENHI Grant Numbers 16H04662, 17K19446, 18H05120 to Yugo Fukazawa and Margarita Salas fellowship from Ministerio de Universidades and Universidad de Castilla-La Mancha to Alejandro Martín-Belmonte. German Research Foundation (DFG FOR 2143) and BIOSS-2 to Akos Kulik.","has_accepted_license":"1","_id":"17293","type":"journal_article","intvolume":"        35","pmid":1,"date_published":"2025-03-01T00:00:00Z","title":"Nanoarchitecture of CaV>2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology","article_processing_charge":"Yes","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"file_date_updated":"2025-04-16T09:56:08Z","language":[{"iso":"eng"}],"OA_type":"gold","volume":35,"publisher":"Wiley","day":"01","author":[{"first_name":"Alejandro","full_name":"Martín‐Belmonte, Alejandro","last_name":"Martín‐Belmonte"},{"last_name":"Aguado","full_name":"Aguado, Carolina","first_name":"Carolina"},{"first_name":"Rocío","full_name":"Alfaro‐Ruiz, Rocío","last_name":"Alfaro‐Ruiz"},{"full_name":"Kulik, Akos","last_name":"Kulik","first_name":"Akos"},{"first_name":"Luis","last_name":"de la Ossa","full_name":"de la Ossa, Luis"},{"first_name":"Ana Esther","full_name":"Moreno‐Martínez, Ana Esther","last_name":"Moreno‐Martínez"},{"last_name":"Alberquilla","full_name":"Alberquilla, Samuel","first_name":"Samuel"},{"full_name":"García‐Carracedo, Lucía","last_name":"García‐Carracedo","first_name":"Lucía"},{"first_name":"Miriam","last_name":"Fernández","full_name":"Fernández, Miriam"},{"last_name":"Fajardo‐Serrano","full_name":"Fajardo‐Serrano, Ana","first_name":"Ana"},{"first_name":"Ester","full_name":"Aso, Ester","last_name":"Aso"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","full_name":"Shigemoto, Ryuichi","last_name":"Shigemoto"},{"first_name":"Eduardo D.","last_name":"Martín","full_name":"Martín, Eduardo D."},{"last_name":"Fukazawa","full_name":"Fukazawa, Yugo","first_name":"Yugo"},{"first_name":"Francisco","last_name":"Ciruela","full_name":"Ciruela, Francisco"},{"first_name":"Rafael","last_name":"Luján","full_name":"Luján, Rafael"}],"DOAJ_listed":"1","scopus_import":"1","publication_status":"published","isi":1,"file":[{"file_size":8767863,"relation":"main_file","access_level":"open_access","file_name":"2025_BrainPathology_MartinBelmonte.pdf","date_updated":"2025-04-16T09:56:08Z","file_id":"19582","date_created":"2025-04-16T09:56:08Z","content_type":"application/pdf","creator":"dernst","success":1,"checksum":"75a172800ab2e949abb66fba97cf70f0"}],"citation":{"apa":"Martín‐Belmonte, A., Aguado, C., Alfaro‐Ruiz, R., Kulik, A., de la Ossa, L., Moreno‐Martínez, A. E., … Luján, R. (2025). Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. <i>Brain Pathology</i>. Wiley. <a href=\"https://doi.org/10.1111/bpa.13279\">https://doi.org/10.1111/bpa.13279</a>","short":"A. Martín‐Belmonte, C. Aguado, R. Alfaro‐Ruiz, A. Kulik, L. de la Ossa, A.E. Moreno‐Martínez, S. Alberquilla, L. García‐Carracedo, M. Fernández, A. Fajardo‐Serrano, E. Aso, R. Shigemoto, E.D. Martín, Y. Fukazawa, F. Ciruela, R. Luján, Brain Pathology 35 (2025).","ama":"Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, et al. Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. <i>Brain Pathology</i>. 2025;35(2). doi:<a href=\"https://doi.org/10.1111/bpa.13279\">10.1111/bpa.13279</a>","ista":"Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, Kulik A, de la Ossa L, Moreno‐Martínez AE, Alberquilla S, García‐Carracedo L, Fernández M, Fajardo‐Serrano A, Aso E, Shigemoto R, Martín ED, Fukazawa Y, Ciruela F, Luján R. 2025. Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. Brain Pathology. 35(2), e13279.","chicago":"Martín‐Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro‐Ruiz, Akos Kulik, Luis de la Ossa, Ana Esther Moreno‐Martínez, Samuel Alberquilla, et al. “Nanoarchitecture of CaV&#62;2.1 Channels and GABAB Receptors in the Mouse Hippocampus: Impact of APP/PS1 Pathology.” <i>Brain Pathology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/bpa.13279\">https://doi.org/10.1111/bpa.13279</a>.","mla":"Martín‐Belmonte, Alejandro, et al. “Nanoarchitecture of CaV&#62;2.1 Channels and GABAB Receptors in the Mouse Hippocampus: Impact of APP/PS1 Pathology.” <i>Brain Pathology</i>, vol. 35, no. 2, e13279, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/bpa.13279\">10.1111/bpa.13279</a>.","ieee":"A. Martín‐Belmonte <i>et al.</i>, “Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology,” <i>Brain Pathology</i>, vol. 35, no. 2. Wiley, 2025."},"ddc":["570"],"issue":"2","article_number":"e13279","status":"public","oa_version":"Published Version","month":"03","article_type":"original","quality_controlled":"1","doi":"10.1111/bpa.13279","OA_place":"publisher"},{"intvolume":"        39","type":"journal_article","_id":"17459","has_accepted_license":"1","OA_type":"hybrid","language":[{"iso":"eng"}],"file_date_updated":"2025-04-16T09:59:37Z","article_processing_charge":"Yes (in subscription journal)","title":"Langerhans cells: Central players in the pathophysiology of atopic dermatitis","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"pmid":1,"date_published":"2025-02-01T00:00:00Z","department":[{"_id":"MiSi"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"publication_identifier":{"eissn":["1468-3083"],"issn":["0926-9959"]},"acknowledgement":"This work was supported by the CK-CARE of the KühneFoundation, Switzerland; the China Scholarship Counciland Shanghai Biocelline Enterprise Co. Ltd, China.","publication":"Journal of the European Academy of Dermatology and Venereology","date_created":"2024-08-25T22:01:07Z","year":"2025","date_updated":"2025-05-19T13:58:50Z","abstract":[{"lang":"eng","text":"Atopic dermatitis (AD) is the most common chronic inflammatory skin disease worldwide. AD is a highly complex disease with different subtypes. Many elements of AD pathophysiology have been described, but if/how they interact with each other or which mechanisms are important in which patients is still unclear. Langerhans cells (LCs) are antigen-presenting cells (APCs) in the epidermis. Depending on the context, they can act either pro- or anti-inflammatory. Many different studies have investigated LCs in the context of AD and found them to be connected to all major mechanisms of AD pathophysiology. As APCs, LCs recruit other immune cells and shape the immune response, especially adaptive immunity via polarization of T cells. As sentinel cells, LCs are primary sensors of the skin microbiome and are important for the decision of immunity versus tolerance. LCs are also involved with the integrity of the skin barrier by influencing tight junctions. Finally, LCs are important cells in the neuro-immune crosstalk in the skin. In this review, we provide an overview about the many different roles of LCs in AD. Understanding LCs might bring us closer to a more complete understanding of this highly complex disease. Potentially, modulating LCs might offer new options for targeted therapies for AD patients."}],"external_id":{"isi":["001292894900001"],"pmid":["39157943"]},"month":"02","article_type":"original","oa_version":"Published Version","status":"public","issue":"2","ddc":["570"],"OA_place":"publisher","doi":"10.1111/jdv.20291","quality_controlled":"1","author":[{"full_name":"Pan, Yi","last_name":"Pan","first_name":"Yi"},{"full_name":"Hochgerner, Mathias","last_name":"Hochgerner","first_name":"Mathias"},{"id":"d63197a3-c188-11ed-9387-8d33a3f13871","first_name":"Malgorzata Anna","full_name":"Cichon, Malgorzata Anna","last_name":"Cichon"},{"last_name":"Benezeder","full_name":"Benezeder, Theresa","first_name":"Theresa"},{"first_name":"Thomas","last_name":"Bieber","full_name":"Bieber, Thomas"},{"first_name":"Peter","full_name":"Wolf, Peter","last_name":"Wolf"}],"day":"01","publisher":"Wiley","volume":39,"file":[{"creator":"dernst","success":1,"checksum":"12555ddb3490daf10b8d44e334e7312e","file_size":457698,"relation":"main_file","access_level":"open_access","file_name":"2025_JEADV_Pan.pdf","date_updated":"2025-04-16T09:59:37Z","file_id":"19583","date_created":"2025-04-16T09:59:37Z","content_type":"application/pdf"}],"citation":{"short":"Y. Pan, M. Hochgerner, M.A. Cichon, T. Benezeder, T. Bieber, P. Wolf, Journal of the European Academy of Dermatology and Venereology 39 (2025) 278–289.","apa":"Pan, Y., Hochgerner, M., Cichon, M. A., Benezeder, T., Bieber, T., &#38; Wolf, P. (2025). Langerhans cells: Central players in the pathophysiology of atopic dermatitis. <i>Journal of the European Academy of Dermatology and Venereology</i>. Wiley. <a href=\"https://doi.org/10.1111/jdv.20291\">https://doi.org/10.1111/jdv.20291</a>","mla":"Pan, Yi, et al. “Langerhans Cells: Central Players in the Pathophysiology of Atopic Dermatitis.” <i>Journal of the European Academy of Dermatology and Venereology</i>, vol. 39, no. 2, Wiley, 2025, pp. 278–89, doi:<a href=\"https://doi.org/10.1111/jdv.20291\">10.1111/jdv.20291</a>.","ista":"Pan Y, Hochgerner M, Cichon MA, Benezeder T, Bieber T, Wolf P. 2025. Langerhans cells: Central players in the pathophysiology of atopic dermatitis. Journal of the European Academy of Dermatology and Venereology. 39(2), 278–289.","ama":"Pan Y, Hochgerner M, Cichon MA, Benezeder T, Bieber T, Wolf P. Langerhans cells: Central players in the pathophysiology of atopic dermatitis. <i>Journal of the European Academy of Dermatology and Venereology</i>. 2025;39(2):278-289. doi:<a href=\"https://doi.org/10.1111/jdv.20291\">10.1111/jdv.20291</a>","chicago":"Pan, Yi, Mathias Hochgerner, Malgorzata Anna Cichon, Theresa Benezeder, Thomas Bieber, and Peter Wolf. “Langerhans Cells: Central Players in the Pathophysiology of Atopic Dermatitis.” <i>Journal of the European Academy of Dermatology and Venereology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/jdv.20291\">https://doi.org/10.1111/jdv.20291</a>.","ieee":"Y. Pan, M. Hochgerner, M. A. Cichon, T. Benezeder, T. Bieber, and P. Wolf, “Langerhans cells: Central players in the pathophysiology of atopic dermatitis,” <i>Journal of the European Academy of Dermatology and Venereology</i>, vol. 39, no. 2. Wiley, pp. 278–289, 2025."},"isi":1,"page":"278-289","publication_status":"published","scopus_import":"1"},{"intvolume":"       646","has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"ScienComp"}],"_id":"17468","type":"journal_article","file_date_updated":"2025-10-20T10:26:13Z","language":[{"iso":"eng"}],"OA_type":"hybrid","date_published":"2025-10-16T00:00:00Z","pmid":1,"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Marcus kinetics control singlet and triplet oxygen evolving from superoxide","article_processing_charge":"Yes (via OA deal)","department":[{"_id":"StFr"},{"_id":"Bio"}],"oa":1,"corr_author":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2025","date_updated":"2026-04-28T13:18:33Z","date_created":"2024-08-29T10:40:23Z","publication":"Nature","acknowledgement":"S.A.F. thanks the Institute of Science and Technology Austria (ISTA) for the support. The Scientific Service Units of ISTA supported this research through resources provided by the Imaging and Optics Facility, the Lab Support Facility, the Miba Machine Shop and Scientific Computing. This research was partly funded by the Austrian Science Fund (FWF) (10.55776/P37169 and 10.55776/COE5). For open access purposes, the author has applied for a CC BY public copyright licence to any author-accepted manuscript version arising from this submission. R.H. acknowledges funding through CZI grant DAF2020-225401 (10.37921/120055ratwvi) from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation (10.13039/100014989). H.T.K.N. acknowledges funding by the European Commission Erasmus Mundus Joint Masters programme. We thank M. Sixt and M. Chinon for the discussions about O-redox in life and R. Jethwa for proofreading. Open access funding was provided by ISTA.","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"PlanS_conform":"1","external_id":{"pmid":["41044415"],"isi":["001586378900001"]},"abstract":[{"lang":"eng","text":"Oxygen redox chemistry is central to life1 and many human-made technologies, such as in energy storage2,3,4. The large energy gain from oxygen redox reactions is often connected with the occurrence of harmful reactive oxygen species3,5,6. Key species are superoxide and the highly reactive singlet oxygen3,4,5,6,7, which may evolve from superoxide. However, the factors determining the formation of singlet oxygen, rather than the relatively unreactive triplet oxygen, are unknown. Here we report that the release of triplet or singlet oxygen is governed by individual Marcus normal and inverted region behaviour. We found that as the driving force for the reaction increases, the initially dominant evolution of triplet oxygen slows down, and singlet oxygen evolution becomes predominant with higher maximum kinetics. This behaviour also applies to the widely observed superoxide disproportionation, in which one superoxide is oxidized by another, in both non-aqueous and aqueous systems, with Lewis and Brønsted acidity controlling the driving forces. Singlet oxygen yields governed by these conditions are relevant, for example, in batteries or cellular organelles in which superoxide forms. Our findings suggest ways to understand and control spin states and kinetics in oxygen redox chemistry, with implications for fields, including life sciences, pure chemistry and energy storage."}],"oa_version":"Published Version","article_type":"original","month":"10","issue":"8085","ddc":["540"],"status":"public","OA_place":"publisher","doi":"10.1038/s41586-025-09587-7","quality_controlled":"1","related_material":{"link":[{"url":"https://ista.ac.at/en/news/taming-the-bad-oxygen/","relation":"press_release","description":"News on ISTA website"}]},"day":"16","author":[{"full_name":"Mondal, Soumyadip","last_name":"Mondal","first_name":"Soumyadip","id":"d25d21ef-dc8d-11ea-abe3-ec4576307f48"},{"first_name":"Huyen T.K.","full_name":"Nguyen, Huyen T.K.","last_name":"Nguyen"},{"orcid":"0000-0001-9843-3522","first_name":"Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","last_name":"Hauschild","full_name":"Hauschild, Robert"},{"full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","first_name":"Stefan Alexander","orcid":"0000-0003-2902-5319"}],"volume":646,"publisher":"Springer Nature","project":[{"grant_number":"P37169","_id":"8df062be-16d5-11f0-9cad-f559b6612c7e","name":"Singlet oxygen in non-aqueous oxygen redox chemistry"},{"name":"Tools for automation and feedback microscopy","grant_number":"CZI01","_id":"c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473"}],"publication_status":"published","page":"601–605","isi":1,"citation":{"ieee":"S. Mondal, H. T. K. Nguyen, R. Hauschild, and S. A. Freunberger, “Marcus kinetics control singlet and triplet oxygen evolving from superoxide,” <i>Nature</i>, vol. 646, no. 8085. Springer Nature, pp. 601–605, 2025.","ista":"Mondal S, Nguyen HTK, Hauschild R, Freunberger SA. 2025. Marcus kinetics control singlet and triplet oxygen evolving from superoxide. Nature. 646(8085), 601–605.","ama":"Mondal S, Nguyen HTK, Hauschild R, Freunberger SA. Marcus kinetics control singlet and triplet oxygen evolving from superoxide. <i>Nature</i>. 2025;646(8085):601–605. doi:<a href=\"https://doi.org/10.1038/s41586-025-09587-7\">10.1038/s41586-025-09587-7</a>","mla":"Mondal, Soumyadip, et al. “Marcus Kinetics Control Singlet and Triplet Oxygen Evolving from Superoxide.” <i>Nature</i>, vol. 646, no. 8085, Springer Nature, 2025, pp. 601–605, doi:<a href=\"https://doi.org/10.1038/s41586-025-09587-7\">10.1038/s41586-025-09587-7</a>.","chicago":"Mondal, Soumyadip, Huyen T.K. Nguyen, Robert Hauschild, and Stefan Alexander Freunberger. “Marcus Kinetics Control Singlet and Triplet Oxygen Evolving from Superoxide.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-025-09587-7\">https://doi.org/10.1038/s41586-025-09587-7</a>.","apa":"Mondal, S., Nguyen, H. T. K., Hauschild, R., &#38; Freunberger, S. A. (2025). Marcus kinetics control singlet and triplet oxygen evolving from superoxide. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-09587-7\">https://doi.org/10.1038/s41586-025-09587-7</a>","short":"S. Mondal, H.T.K. Nguyen, R. Hauschild, S.A. Freunberger, Nature 646 (2025) 601–605."},"file":[{"checksum":"b507ddd23df0388aa65d04dc9b00fe3d","success":1,"creator":"dernst","content_type":"application/pdf","date_updated":"2025-10-20T10:26:13Z","file_id":"20500","date_created":"2025-10-20T10:26:13Z","file_name":"2025_Nature_Mondal.pdf","access_level":"open_access","file_size":3809247,"relation":"main_file"}],"scopus_import":"1"}]