---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20009'
abstract:
- lang: eng
  text: The suppression of recombination between young X and Y chromosomes is a crucial
    step in their evolution, but why it occurs is not known. The detailed characterization
    of the polymorphic sex chromosomes of the fourspine stickleback by Liu et al.
    promises to shed new light on this longstanding question.
acknowledgement: I thank the Vicoso group for in-depth discussions of the original
  article highlighted here. This work was supported by an Austrian Research Fund (FWF)
  grant to B.V. (PAT 8748323).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Vicoso B. Sex chromosome evolution in action in fourspine sticklebacks. <i>Trends
    in Ecology and Evolution</i>. 2025;40(8):728-730. doi:<a href="https://doi.org/10.1016/j.tree.2025.06.010">10.1016/j.tree.2025.06.010</a>
  apa: Vicoso, B. (2025). Sex chromosome evolution in action in fourspine sticklebacks.
    <i>Trends in Ecology and Evolution</i>. Elsevier. <a href="https://doi.org/10.1016/j.tree.2025.06.010">https://doi.org/10.1016/j.tree.2025.06.010</a>
  chicago: Vicoso, Beatriz. “Sex Chromosome Evolution in Action in Fourspine Sticklebacks.”
    <i>Trends in Ecology and Evolution</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.tree.2025.06.010">https://doi.org/10.1016/j.tree.2025.06.010</a>.
  ieee: B. Vicoso, “Sex chromosome evolution in action in fourspine sticklebacks,”
    <i>Trends in Ecology and Evolution</i>, vol. 40, no. 8. Elsevier, pp. 728–730,
    2025.
  ista: Vicoso B. 2025. Sex chromosome evolution in action in fourspine sticklebacks.
    Trends in Ecology and Evolution. 40(8), 728–730.
  mla: Vicoso, Beatriz. “Sex Chromosome Evolution in Action in Fourspine Sticklebacks.”
    <i>Trends in Ecology and Evolution</i>, vol. 40, no. 8, Elsevier, 2025, pp. 728–30,
    doi:<a href="https://doi.org/10.1016/j.tree.2025.06.010">10.1016/j.tree.2025.06.010</a>.
  short: B. Vicoso, Trends in Ecology and Evolution 40 (2025) 728–730.
corr_author: '1'
date_created: 2025-07-13T22:01:23Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-12-30T09:22:29Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1016/j.tree.2025.06.010
external_id:
  isi:
  - '001550437400006'
file:
- access_level: open_access
  checksum: 0a7c6e8600c878dac7082681e4409b50
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  creator: dernst
  date_created: 2025-12-30T09:21:14Z
  date_updated: 2025-12-30T09:21:14Z
  file_id: '20905'
  file_name: 2025_TrendsEcoloEvolution_Vicoso.pdf
  file_size: 699156
  relation: main_file
  success: 1
file_date_updated: 2025-12-30T09:21:14Z
has_accepted_license: '1'
intvolume: '        40'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 728-730
project:
- _id: 8ed82125-16d5-11f0-9cad-fbcae312235b
  grant_number: PAT 8748323
  name: Sex chromosomes in evolution and development
publication: Trends in Ecology and Evolution
publication_identifier:
  issn:
  - 0169-5347
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sex chromosome evolution in action in fourspine sticklebacks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 40
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20010'
abstract:
- lang: eng
  text: Chirality-induced spin selectivity (CISS), which refers to the ability of
    chiral molecules to preferentially select spins during electron transfer, has
    attracted great attention during the past two decades. However, the theoretical
    and experimental understanding of the CISS effect remains preliminary. In this
    study, we demonstrate that there is no distinguishable CISS effect in the case
    of coherent electron transport through single chiral molecular junctions for a
    set of four molecule studied here. Our conclusion is based on statistical evaluations
    of thousands of single-molecule junctions across four different molecules with
    different origins of chirality measured by the scanning tunneling microscope-based
    break-junction technique. The experimental results for all molecules show no dependence
    on external magnetic field or chirality in both conductance and current–voltage
    measurements. In addition, ab initio Hartree-Fork calculations combined with the
    nonequilibrium Green’s function method reveal that the spin–orbit coupling within
    chiral junctions bound to a few gold atoms is generally too weak to induce detectable
    spin polarizations from spin flipping or spin filtering during the ultrafast electron-transport
    time scale. The absence of an observable CISS effect in the coherent electron-transport
    regime suggests that the effect may only be found in other electron-transfer regimes
    and requires further experimental and theoretical efforts to achieve a comprehensive
    understanding.
acknowledgement: 'We thank the National Science Foundation (NSF-DMR 2241180) for supporting
  this research. This work was supported in part by the Institute of Science and Technology
  Austria. The synthesis of 1R and 1S was supported by the US Air Force Office of
  Scientific Research through grant no. FA9550-23-1-0648. The synthesis of 3 was supported
  by the Spanish MCIN/AEI/10.13039/501100011033 grant, the European Union Next Generation
  EU/PRTR (TED2021-131255B–C43), MCIU/AEI/10.13039/501100011033/FEDER, UE (PID) (PID2023-151167NB-I00),
  the Comunidad de Madrid and the Spanish State through the Recovery, Transformation
  and Resilience Plan [“Materiales Disruptivos Bidimensionales (2D)” (MAD2D-CM) (UAM1)-MRR
  Materiales Avanzados]. IMDEA Nanociencia acknowledges support from the “Severo Ochoa”
  Programme for Centres of Excellence in R&D (MINECO, CEX2020-001039 S). M.G.G. acknowledges
  MICIU, Spain, for a F.P.U. The work of DRR and AM was supported by the Spin-COntrolled
  Chemical Process Engineering (SCOPE) program of the Defense Advanced Research Project
  Agency grant HR0011-23-9-0109. Numerical calculations were performed on the Delta
  system at the National Center for Supercomputing Applications through allocation
  CHE230028 from the Advanced Cyberinfrastructure Coordination Ecosystem: Services
  and Support (ACCESS) program, which is supported by National Science Foundation
  grants #2138259, #2138286, #2138307, #2137603, and #2138296.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Liang
  full_name: Li, Liang
  last_name: Li
- first_name: Wanzhuo
  full_name: Shi, Wanzhuo
  last_name: Shi
- first_name: Ankit
  full_name: Mahajan, Ankit
  last_name: Mahajan
- first_name: Junxiang
  full_name: Zhang, Junxiang
  last_name: Zhang
- first_name: Marta
  full_name: Gómez-Gómez, Marta
  last_name: Gómez-Gómez
- first_name: Jorge
  full_name: Labella, Jorge
  last_name: Labella
- first_name: Shayan
  full_name: Louie, Shayan
  last_name: Louie
- first_name: Tomás
  full_name: Torres, Tomás
  last_name: Torres
- first_name: Stephen
  full_name: Barlow, Stephen
  last_name: Barlow
- first_name: Seth R.
  full_name: Marder, Seth R.
  last_name: Marder
- first_name: David R.
  full_name: Reichman, David R.
  last_name: Reichman
- first_name: Latha
  full_name: Venkataraman, Latha
  id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
  last_name: Venkataraman
  orcid: 0000-0002-6957-6089
citation:
  ama: 'Li L, Shi W, Mahajan A, et al. Too fast for spin flipping: Absence of chirality-induced
    spin selectivity in coherent electron transport through single-molecule junctions.
    <i>Journal of the American Chemical Society</i>. 2025;147(28):25043-25051. doi:<a
    href="https://doi.org/10.1021/jacs.5c08517">10.1021/jacs.5c08517</a>'
  apa: 'Li, L., Shi, W., Mahajan, A., Zhang, J., Gómez-Gómez, M., Labella, J., … Venkataraman,
    L. (2025). Too fast for spin flipping: Absence of chirality-induced spin selectivity
    in coherent electron transport through single-molecule junctions. <i>Journal of
    the American Chemical Society</i>. American Chemical Society. <a href="https://doi.org/10.1021/jacs.5c08517">https://doi.org/10.1021/jacs.5c08517</a>'
  chicago: 'Li, Liang, Wanzhuo Shi, Ankit Mahajan, Junxiang Zhang, Marta Gómez-Gómez,
    Jorge Labella, Shayan Louie, et al. “Too Fast for Spin Flipping: Absence of Chirality-Induced
    Spin Selectivity in Coherent Electron Transport through Single-Molecule Junctions.”
    <i>Journal of the American Chemical Society</i>. American Chemical Society, 2025.
    <a href="https://doi.org/10.1021/jacs.5c08517">https://doi.org/10.1021/jacs.5c08517</a>.'
  ieee: 'L. Li <i>et al.</i>, “Too fast for spin flipping: Absence of chirality-induced
    spin selectivity in coherent electron transport through single-molecule junctions,”
    <i>Journal of the American Chemical Society</i>, vol. 147, no. 28. American Chemical
    Society, pp. 25043–25051, 2025.'
  ista: 'Li L, Shi W, Mahajan A, Zhang J, Gómez-Gómez M, Labella J, Louie S, Torres
    T, Barlow S, Marder SR, Reichman DR, Venkataraman L. 2025. Too fast for spin flipping:
    Absence of chirality-induced spin selectivity in coherent electron transport through
    single-molecule junctions. Journal of the American Chemical Society. 147(28),
    25043–25051.'
  mla: 'Li, Liang, et al. “Too Fast for Spin Flipping: Absence of Chirality-Induced
    Spin Selectivity in Coherent Electron Transport through Single-Molecule Junctions.”
    <i>Journal of the American Chemical Society</i>, vol. 147, no. 28, American Chemical
    Society, 2025, pp. 25043–51, doi:<a href="https://doi.org/10.1021/jacs.5c08517">10.1021/jacs.5c08517</a>.'
  short: L. Li, W. Shi, A. Mahajan, J. Zhang, M. Gómez-Gómez, J. Labella, S. Louie,
    T. Torres, S. Barlow, S.R. Marder, D.R. Reichman, L. Venkataraman, Journal of
    the American Chemical Society 147 (2025) 25043–25051.
corr_author: '1'
date_created: 2025-07-13T22:01:23Z
date_published: 2025-07-01T00:00:00Z
date_updated: 2025-12-30T09:11:26Z
day: '01'
ddc:
- '540'
department:
- _id: LaVe
doi: 10.1021/jacs.5c08517
external_id:
  isi:
  - '001522009200001'
file:
- access_level: open_access
  checksum: f2bbe7d64de2d0d78aa2be933d12b096
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-30T09:09:53Z
  date_updated: 2025-12-30T09:09:53Z
  file_id: '20902'
  file_name: 2025_JACS_Li.pdf
  file_size: 5524744
  relation: main_file
  success: 1
file_date_updated: 2025-12-30T09:09:53Z
has_accepted_license: '1'
intvolume: '       147'
isi: 1
issue: '28'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 25043-25051
publication: Journal of the American Chemical Society
publication_identifier:
  eissn:
  - 1520-5126
  issn:
  - 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Too fast for spin flipping: Absence of chirality-induced spin selectivity
  in coherent electron transport through single-molecule junctions'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 147
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20011'
abstract:
- lang: eng
  text: Heat transport in glasses over a wide temperature range is critical for applications
    in gate dielectrics and thermal insulators but remains poorly understood due to
    the challenges in modeling vibrational anharmonicity and configurational dynamics
    across the glass transition. Recent predictions show an unusual decrease in thermal
    conductivity (κ) with temperature in amorphous hafnia (a-HfO2), contrasting with
    the typical trend in glasses. Using molecular dynamics with a machine-learning-based
    neuroevolution potential, we compute κ of a-HfO2 from 50 K to 2000 K. At low temperatures,
    the Wigner transport equation captures both anharmonicity and quantum statistics.
    Above 1200 K, atomic diffusion invalidates the quasiparticle picture, and we resort
    to the Green–Kubo method to capture convective transport. We further extend the
    Wigner transport equation to supercooled a-HfO2, revealing the crucial role of
    low-frequency modes in facilitating heat transport. The computed κ, based on both
    Green–Kubo and Wigner transport theories, increases continuously with temperature
    up to 2000 K.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: We thank Ludovic Berthier for fruitful discussions and Ting Liang
  for providing the initial structures of a-SiO2. Z.Z. acknowledges funding from the
  European Union’s Horizon 2020 Research and Innovation Programme, under Marie Skłodowska-Curie
  grant agreement No. 101034413. The authors also acknowledge the research computing
  facilities provided by HPC ISTA and ITS HKU.
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Zezhu
  full_name: Zeng, Zezhu
  id: 54a2c730-803f-11ed-ab7e-95b29d2680e7
  last_name: Zeng
  orcid: 0000-0001-5126-4928
- first_name: Xia
  full_name: Liang, Xia
  last_name: Liang
- first_name: Zheyong
  full_name: Fan, Zheyong
  last_name: Fan
- first_name: Yue
  full_name: Chen, Yue
  last_name: Chen
- first_name: Michele
  full_name: Simoncelli, Michele
  last_name: Simoncelli
- first_name: Bingqing
  full_name: Cheng, Bingqing
  id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
  last_name: Cheng
  orcid: 0000-0002-3584-9632
citation:
  ama: Zeng Z, Liang X, Fan Z, Chen Y, Simoncelli M, Cheng B. Thermal transport of
    amorphous hafnia across the glass transition. <i>ACS Materials Letters</i>. 2025:2695-2701.
    doi:<a href="https://doi.org/10.1021/acsmaterialslett.5c00263">10.1021/acsmaterialslett.5c00263</a>
  apa: Zeng, Z., Liang, X., Fan, Z., Chen, Y., Simoncelli, M., &#38; Cheng, B. (2025).
    Thermal transport of amorphous hafnia across the glass transition. <i>ACS Materials
    Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acsmaterialslett.5c00263">https://doi.org/10.1021/acsmaterialslett.5c00263</a>
  chicago: Zeng, Zezhu, Xia Liang, Zheyong Fan, Yue Chen, Michele Simoncelli, and
    Bingqing Cheng. “Thermal Transport of Amorphous Hafnia across the Glass Transition.”
    <i>ACS Materials Letters</i>. American Chemical Society, 2025. <a href="https://doi.org/10.1021/acsmaterialslett.5c00263">https://doi.org/10.1021/acsmaterialslett.5c00263</a>.
  ieee: Z. Zeng, X. Liang, Z. Fan, Y. Chen, M. Simoncelli, and B. Cheng, “Thermal
    transport of amorphous hafnia across the glass transition,” <i>ACS Materials Letters</i>.
    American Chemical Society, pp. 2695–2701, 2025.
  ista: Zeng Z, Liang X, Fan Z, Chen Y, Simoncelli M, Cheng B. 2025. Thermal transport
    of amorphous hafnia across the glass transition. ACS Materials Letters., 2695–2701.
  mla: Zeng, Zezhu, et al. “Thermal Transport of Amorphous Hafnia across the Glass
    Transition.” <i>ACS Materials Letters</i>, American Chemical Society, 2025, pp.
    2695–701, doi:<a href="https://doi.org/10.1021/acsmaterialslett.5c00263">10.1021/acsmaterialslett.5c00263</a>.
  short: Z. Zeng, X. Liang, Z. Fan, Y. Chen, M. Simoncelli, B. Cheng, ACS Materials
    Letters (2025) 2695–2701.
corr_author: '1'
date_created: 2025-07-13T22:01:24Z
date_published: 2025-06-30T00:00:00Z
date_updated: 2025-12-30T09:15:30Z
day: '30'
ddc:
- '530'
department:
- _id: BiCh
doi: 10.1021/acsmaterialslett.5c00263
ec_funded: 1
external_id:
  isi:
  - '001520226300001'
file:
- access_level: open_access
  checksum: d61e63439ddeaef29e9a2ee0f65c4ec1
  content_type: application/pdf
  creator: dernst
  date_created: 2025-12-30T09:13:06Z
  date_updated: 2025-12-30T09:13:06Z
  file_id: '20903'
  file_name: 2025_ACSMaterialsLetters_Zeng.pdf
  file_size: 2402059
  relation: main_file
  success: 1
file_date_updated: 2025-12-30T09:13:06Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 2695-2701
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: ACS Materials Letters
publication_identifier:
  eissn:
  - 2639-4979
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/ZengZezhu/heat-conductivity-a-HfO2
scopus_import: '1'
status: public
title: Thermal transport of amorphous hafnia across the glass transition
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_type: closed access
_id: '20024'
abstract:
- lang: eng
  text: 'Cooperative software verification divides the task of software verification
    among several verification tools in order to increase efficiency and effectiveness.
    The basic approach is to let verifiers work on different parts of a program and
    at the end join verification results. While this idea is intuitively appealing,
    cooperative verification is usually hindered by the fact that program decomposition
    (1) is often static, disregarding strengths and weaknesses of employed verifiers,
    and (2) often represents the decomposed program parts in a specific proprietary
    format, thereby making the use of off-the-shelf verifiers in cooperative verification
    difficult. In this paper, we propose a novel cooperative verification scheme that
    we call dynamic program splitting (DPS). Splitting decomposes programs into (smaller)
    programs, and thus directly enables the use of off-the-shelf tools. In DPS, splitting
    is dynamically applied on demand: Verification starts by giving a verification
    task (a program plus a correctness specification) to a verifier V1. Whenever V1
    finds the current task to be hard to verify, it splits the task (i.e., the program)
    and restarts verification on subtasks. DPS continues until (1) a violation is
    found, (2) all subtasks are completed or (3) some user-defined stopping criterion
    is met. In the latter case, the remaining uncompleted subtasks are merged into
    a single one and are given to a next verifier V2, repeating the same procedure
    on the still unverified program parts. This way, the decomposition is steered
    by what is hard to verify for particular verifiers, leveraging their complementary
    strengths. We have implemented dynamic program splitting and evaluated it on benchmarks
    of the annual software verification competition SV-COMP. The evaluation shows
    that cooperative verification with DPS is able to solve verification tasks that
    none of the constituent verifiers can solve, without any significant overhead.'
acknowledgement: This work is partially supported by the German Research Foundation
  (DFG) – WE2290/13-2 (Coop2), and in part by the ERC-2020-AdG 101020093.
article_processing_charge: No
author:
- first_name: Cedric
  full_name: Richter, Cedric
  last_name: Richter
- first_name: Marek
  full_name: Chalupa, Marek
  id: 87e34708-d6c6-11ec-9f5b-9391e7be2463
  last_name: Chalupa
- first_name: Marie-Christine
  full_name: Jakobs, Marie-Christine
  last_name: Jakobs
- first_name: Heike
  full_name: Wehrheim, Heike
  last_name: Wehrheim
citation:
  ama: 'Richter C, Chalupa M, Jakobs M-C, Wehrheim H. Cooperative software verification
    via dynamic program splitting. In: <i>47th International Conference on Software
    Engineering</i>. IEEE; 2025:2087-2099. doi:<a href="https://doi.org/10.1109/ICSE55347.2025.00092">10.1109/ICSE55347.2025.00092</a>'
  apa: 'Richter, C., Chalupa, M., Jakobs, M.-C., &#38; Wehrheim, H. (2025). Cooperative
    software verification via dynamic program splitting. In <i>47th International
    Conference on Software Engineering</i> (pp. 2087–2099). Ottawa, ON, Canada: IEEE.
    <a href="https://doi.org/10.1109/ICSE55347.2025.00092">https://doi.org/10.1109/ICSE55347.2025.00092</a>'
  chicago: Richter, Cedric, Marek Chalupa, Marie-Christine Jakobs, and Heike Wehrheim.
    “Cooperative Software Verification via Dynamic Program Splitting.” In <i>47th
    International Conference on Software Engineering</i>, 2087–99. IEEE, 2025. <a
    href="https://doi.org/10.1109/ICSE55347.2025.00092">https://doi.org/10.1109/ICSE55347.2025.00092</a>.
  ieee: C. Richter, M. Chalupa, M.-C. Jakobs, and H. Wehrheim, “Cooperative software
    verification via dynamic program splitting,” in <i>47th International Conference
    on Software Engineering</i>, Ottawa, ON, Canada, 2025, pp. 2087–2099.
  ista: 'Richter C, Chalupa M, Jakobs M-C, Wehrheim H. 2025. Cooperative software
    verification via dynamic program splitting. 47th International Conference on Software
    Engineering. ICSE: International Conference on Software Engineering, 2087–2099.'
  mla: Richter, Cedric, et al. “Cooperative Software Verification via Dynamic Program
    Splitting.” <i>47th International Conference on Software Engineering</i>, IEEE,
    2025, pp. 2087–99, doi:<a href="https://doi.org/10.1109/ICSE55347.2025.00092">10.1109/ICSE55347.2025.00092</a>.
  short: C. Richter, M. Chalupa, M.-C. Jakobs, H. Wehrheim, in:, 47th International
    Conference on Software Engineering, IEEE, 2025, pp. 2087–2099.
conference:
  end_date: 2025-05-06
  location: Ottawa, ON, Canada
  name: 'ICSE: International Conference on Software Engineering'
  start_date: 2025-04-26
corr_author: '1'
date_created: 2025-07-16T11:32:29Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2025-09-30T14:01:55Z
day: '01'
department:
- _id: ToHe
doi: 10.1109/ICSE55347.2025.00092
ec_funded: 1
external_id:
  isi:
  - '001538318100163'
isi: 1
language:
- iso: eng
month: '05'
oa_version: None
page: 2087-2099
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 47th International Conference on Software Engineering
publication_identifier:
  eissn:
  - 1558-1225
  isbn:
  - '9798331505691'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cooperative software verification via dynamic program splitting
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '20026'
abstract:
- lang: eng
  text: Deep Convective Systems (DCSs) reaching scales of 100–1000 km play a pivotal
    role as the primary precipitation source in the tropics. Those systems can have
    large cloud shields, and thus not only affect severe precipitation patterns but
    also play a crucial part in modulating the tropical radiation budget. Understanding
    the complex factors that control how these systems grow and how they will behave
    in a warming climate remain fundamental challenges. Research efforts have been
    directed, on one hand, towards understanding the environmental control on these
    systems, and on the other hand, towards exploring the internal potential of systems
    to develop and self-aggregate in idealized simulations. However, we still lack
    understanding on the relative role of the environment and internal feedbacks on
    DCS mature size and why. The novel high-resolution global SAM simulation from
    the DYAMOND project, combined with the TOOCAN Lagrangian tracking of DCSs and
    machine learning tools, offers an unprecedented opportunity to explore this question.
    We find that a system’s growth rate during the first 2 h of development predicts
    its final size with a Pearson correlation coefficient of 0.65. Beyond this period,
    growth rate emerges as the strongest predictor. However, in the early stages,
    additional factors–such as ice water path heterogeneity, migration distance, interactions
    with neighboring systems, and deep shear–play a more significant role. Our study
    quantitatively assesses the relative influence of internal versus external factors
    on the mature cloud shield size. Our results show that system-intrinsic properties
    exert a stronger influence than environmental conditions, suggesting that the
    initial environment does not strictly constrain final system size, particularly
    for larger systems where internal dynamics dominate.
acknowledgement: C.M. and S.A. gratefully acknowledge funding from the European Research
  Council (ERC) under the European Union's Horizon 2020 research and innovation program
  (Project CLUSTER, grant agreement 805041), and from the PhD fellowship of Ecole
  Normale Supérieure de Paris-Saclay. DYAMOND data management was provided by the
  German Climate Computing Center (DKRZ) and supported through the projects ESiWACE
  and ESiWACE2. The projects ESiWACE and ESiWACE2 have received funding from the European
  Union’s Horizon 2020 research and innovation program under grant agreements No 675191
  and 823988. This work used resources of the Deutsches Klimarechenzentrum (DKRZ)
  granted by its Scientific Steering Committee (WLA) under project IDs bk1040 and
  bb1153. The authors express their gratitude to Sophie Cloché and Eileen Hertwig
  for their assistance in data archival at IPSL and DKRZ, respectively. We also thank
  Christophe Lampert and Benjamin Fildier for valuable scientific discussions, and
  acknowledge the thoughtful comments of two anonymous reviewers.
article_number: '258'
article_processing_charge: Yes
article_type: original
author:
- first_name: Sophie
  full_name: Abramian, Sophie
  last_name: Abramian
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
- first_name: Camille
  full_name: Risi, Camille
  last_name: Risi
- first_name: Thomas
  full_name: Fiolleau, Thomas
  last_name: Fiolleau
- first_name: Rémy
  full_name: Roca, Rémy
  last_name: Roca
citation:
  ama: Abramian S, Muller CJ, Risi C, Fiolleau T, Roca R. How key features of early
    development shape deep convective systems. <i>npj Climate and Atmospheric Science</i>.
    2025;8. doi:<a href="https://doi.org/10.1038/s41612-025-01154-1">10.1038/s41612-025-01154-1</a>
  apa: Abramian, S., Muller, C. J., Risi, C., Fiolleau, T., &#38; Roca, R. (2025).
    How key features of early development shape deep convective systems. <i>Npj Climate
    and Atmospheric Science</i>. Springer Nature. <a href="https://doi.org/10.1038/s41612-025-01154-1">https://doi.org/10.1038/s41612-025-01154-1</a>
  chicago: Abramian, Sophie, Caroline J Muller, Camille Risi, Thomas Fiolleau, and
    Rémy Roca. “How Key Features of Early Development Shape Deep Convective Systems.”
    <i>Npj Climate and Atmospheric Science</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s41612-025-01154-1">https://doi.org/10.1038/s41612-025-01154-1</a>.
  ieee: S. Abramian, C. J. Muller, C. Risi, T. Fiolleau, and R. Roca, “How key features
    of early development shape deep convective systems,” <i>npj Climate and Atmospheric
    Science</i>, vol. 8. Springer Nature, 2025.
  ista: Abramian S, Muller CJ, Risi C, Fiolleau T, Roca R. 2025. How key features
    of early development shape deep convective systems. npj Climate and Atmospheric
    Science. 8, 258.
  mla: Abramian, Sophie, et al. “How Key Features of Early Development Shape Deep
    Convective Systems.” <i>Npj Climate and Atmospheric Science</i>, vol. 8, 258,
    Springer Nature, 2025, doi:<a href="https://doi.org/10.1038/s41612-025-01154-1">10.1038/s41612-025-01154-1</a>.
  short: S. Abramian, C.J. Muller, C. Risi, T. Fiolleau, R. Roca, Npj Climate and
    Atmospheric Science 8 (2025).
date_created: 2025-07-20T22:01:59Z
date_published: 2025-07-08T00:00:00Z
date_updated: 2025-09-30T14:02:27Z
day: '08'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1038/s41612-025-01154-1
ec_funded: 1
external_id:
  isi:
  - '001524244500001'
file:
- access_level: open_access
  checksum: 8113405b3e52024b24621ea21d89b3ab
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T06:02:14Z
  date_updated: 2025-07-22T06:02:14Z
  file_id: '20061'
  file_name: 2025_njpClimate_Abramian.pdf
  file_size: 3919446
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T06:02:14Z
has_accepted_license: '1'
intvolume: '         8'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
  call_identifier: H2020
  grant_number: '805041'
  name: Organization of CLoUdS, and implications of Tropical  cyclones and for the
    Energetics of the tropics, in current and waRming climate
publication: npj Climate and Atmospheric Science
publication_identifier:
  eissn:
  - 2397-3722
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: How key features of early development shape deep convective systems
tmp:
  image: /images/cc_by_nc_nd.png
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  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 8
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20027'
abstract:
- lang: eng
  text: "We present the first results of the JWST Emission Line Survey (JELS). Utilizing
    the first NIRCam narrow-band imaging at 4.7 μm, over 63 arcmin2 in the PRIMER/COSMOS
    field, we have identified 609 emission line galaxy candidates. From these, we
    robustly selected 35 H α star-forming galaxies at z ∼ 6.1, with H α star-formation
    rates (SFRH α) of ∼ 0.9 − 15 M yr−1.\r\nCombining our unique H α sample with the
    exquisite panchromatic data in the field, we explored their physical properties
    and star-formation histories, and compared these to a broad-band selected sample
    at z ∼ 6 which has offered vital new insights into the nature of high-redshift
    galaxies. UV-continuum slopes (β) were considerably redder for our H α sample
    (\x04β\x05 ∼ −1.92)\r\ncompared to the broad-band sample (\x04β\x05 ∼ −2.35).
    This was not due to dust attenuation as our H α sample was relatively dustpoor
    (median AV = 0.23); instead, we argue that the reddened slopes could be due to
    nebular continuum. We compared SFRH α and the UV-continuum-derived SFRUV to SED-fitted
    measurements averaged over canonical time-scales of 10 and 100 Myr (SFR10 and
    SFR100). We found an increase in recent SFR for our sample of H α emitters, particularly
    at lower stellar masses (< 109 M). We also found that SFRH α strongly traces SFR
    averaged over 10 Myr time-scales, whereas the UV-continuum overpredicts SFR on
    100 Myr time-scales at low stellar masses. These results point to our H α sample
    undergoing ‘bursty’ star\r\nformation. Our F356W z ∼ 6 sample showed a larger
    scatter in SFR10/SFR100 across all stellar masses, which has highlighted how narrow-band
    photometric selections of H α emitters are key to quantifying the burstiness of
    star-formation activity. "
acknowledgement: "The authors would like to thank Adam Carnall and Joel Leja for their
  helpful advice with the SED fitting of our sample, Callum Donnan for his advice
  on the selection techniques of high-redshift\r\ngalaxies, Alice Shapley for discussion
  around H α SFR calibrations at high-redshift, Fred Jennings for providing insight
  into the interpretation of SFR ratios, and the anonymous referee for their helpful
  comments – all of which have greatly improved this paper. Several other authors
  acknowledge the support of the UK Science and Technology Facilities Council (STFC)
  via grants ST/W507441/1 (CAP), ST/V000594/1 (DJM, PNB, RK, and RJM), ST/Y000951/1
  (PNB and RK) and ST/X001075/1 (AMS and IRS), and through an Ernest Rutherford Fellowship
  (KJD; grant number ST/W003120/1). RKC was funded by support for programme #02321,
  provided by\r\nNASA through a grant from the Space Telescope Science Institute,
  which is operated by the Association of Universities for Research in Astronomy,
  Inc., under NASA contract NAS5-03127. RKC and CLH are both grateful for support
  from the Leverhulme Trust via a Leverhulme Early Career Fellowship, and CLH also
  acknowledges support from the Oxford Hintze Centre for Astrophysical Surveys which
  is funded through generous support from the Hintze Family\r\nCharitable Foundation.
  JSD acknowledges the support of the Royal Society via a Royal Society Research Professorship.
  EI gratefully acknowledge financialsupport from ANID–MILENIO–NCN2024 112 and ANID
  FONDECYT Regular 1221846. LOF acknowledges by ANID BECAS/DOCTORADO NACIONAL 21220499."
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: C. A.
  full_name: Pirie, C. A.
  last_name: Pirie
- first_name: P. N.
  full_name: Best, P. N.
  last_name: Best
- first_name: K. J.
  full_name: Duncan, K. J.
  last_name: Duncan
- first_name: D. J.
  full_name: Mcleod, D. J.
  last_name: Mcleod
- first_name: R. K.
  full_name: Cochrane, R. K.
  last_name: Cochrane
- first_name: M.
  full_name: Clausen, M.
  last_name: Clausen
- first_name: J. S.
  full_name: Dunlop, J. S.
  last_name: Dunlop
- first_name: S. R.
  full_name: Flury, S. R.
  last_name: Flury
- first_name: J. E.
  full_name: Geach, J. E.
  last_name: Geach
- first_name: C. L.
  full_name: Hale, C. L.
  last_name: Hale
- first_name: E.
  full_name: Ibar, E.
  last_name: Ibar
- first_name: R.
  full_name: Kondapally, R.
  last_name: Kondapally
- first_name: Zefeng
  full_name: Li, Zefeng
  last_name: Li
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: R. J.
  full_name: Mclure, R. J.
  last_name: Mclure
- first_name: L.
  full_name: Ossa-Fuentes, L.
  last_name: Ossa-Fuentes
- first_name: A. L.
  full_name: Patrick, A. L.
  last_name: Patrick
- first_name: Ian
  full_name: Smail, Ian
  last_name: Smail
- first_name: D.
  full_name: Sobral, D.
  last_name: Sobral
- first_name: H. M.O.
  full_name: Stephenson, H. M.O.
  last_name: Stephenson
- first_name: J. P.
  full_name: Stott, J. P.
  last_name: Stott
- first_name: A. M.
  full_name: Swinbank, A. M.
  last_name: Swinbank
citation:
  ama: 'Pirie CA, Best PN, Duncan KJ, et al. The JWST Emission Line Survey (JELS):
    An untargeted search for H α emission line galaxies at z &#62; 6 and their physical
    properties. <i>Monthly Notices of the Royal Astronomical Society</i>. 2025;541(2):1348-1376.
    doi:<a href="https://doi.org/10.1093/mnras/staf1006">10.1093/mnras/staf1006</a>'
  apa: 'Pirie, C. A., Best, P. N., Duncan, K. J., Mcleod, D. J., Cochrane, R. K.,
    Clausen, M., … Swinbank, A. M. (2025). The JWST Emission Line Survey (JELS): An
    untargeted search for H α emission line galaxies at z &#62; 6 and their physical
    properties. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University
    Press. <a href="https://doi.org/10.1093/mnras/staf1006">https://doi.org/10.1093/mnras/staf1006</a>'
  chicago: 'Pirie, C. A., P. N. Best, K. J. Duncan, D. J. Mcleod, R. K. Cochrane,
    M. Clausen, J. S. Dunlop, et al. “The JWST Emission Line Survey (JELS): An Untargeted
    Search for H α Emission Line Galaxies at z &#62; 6 and Their Physical Properties.”
    <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press,
    2025. <a href="https://doi.org/10.1093/mnras/staf1006">https://doi.org/10.1093/mnras/staf1006</a>.'
  ieee: 'C. A. Pirie <i>et al.</i>, “The JWST Emission Line Survey (JELS): An untargeted
    search for H α emission line galaxies at z &#62; 6 and their physical properties,”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 541, no. 2. Oxford
    University Press, pp. 1348–1376, 2025.'
  ista: 'Pirie CA, Best PN, Duncan KJ, Mcleod DJ, Cochrane RK, Clausen M, Dunlop JS,
    Flury SR, Geach JE, Hale CL, Ibar E, Kondapally R, Li Z, Matthee JJ, Mclure RJ,
    Ossa-Fuentes L, Patrick AL, Smail I, Sobral D, Stephenson HMO, Stott JP, Swinbank
    AM. 2025. The JWST Emission Line Survey (JELS): An untargeted search for H α emission
    line galaxies at z &#62; 6 and their physical properties. Monthly Notices of the
    Royal Astronomical Society. 541(2), 1348–1376.'
  mla: 'Pirie, C. A., et al. “The JWST Emission Line Survey (JELS): An Untargeted
    Search for H α Emission Line Galaxies at z &#62; 6 and Their Physical Properties.”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 541, no. 2, Oxford
    University Press, 2025, pp. 1348–76, doi:<a href="https://doi.org/10.1093/mnras/staf1006">10.1093/mnras/staf1006</a>.'
  short: C.A. Pirie, P.N. Best, K.J. Duncan, D.J. Mcleod, R.K. Cochrane, M. Clausen,
    J.S. Dunlop, S.R. Flury, J.E. Geach, C.L. Hale, E. Ibar, R. Kondapally, Z. Li,
    J.J. Matthee, R.J. Mclure, L. Ossa-Fuentes, A.L. Patrick, I. Smail, D. Sobral,
    H.M.O. Stephenson, J.P. Stott, A.M. Swinbank, Monthly Notices of the Royal Astronomical
    Society 541 (2025) 1348–1376.
date_created: 2025-07-20T22:02:00Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-09-30T14:03:40Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1093/mnras/staf1006
external_id:
  arxiv:
  - '2410.11808'
  isi:
  - '001527095600001'
file:
- access_level: open_access
  checksum: f8708c78016f8917765026502c6b50b6
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T07:19:20Z
  date_updated: 2025-07-22T07:19:20Z
  file_id: '20064'
  file_name: 2025_MonthlyNoticesRAS_Pirie.pdf
  file_size: 38102038
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T07:19:20Z
has_accepted_license: '1'
intvolume: '       541'
isi: 1
issue: '2'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 1348-1376
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The JWST Emission Line Survey (JELS): An untargeted search for H α emission
  line galaxies at z > 6 and their physical properties'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 541
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20028'
abstract:
- lang: eng
  text: We present the JWST Emission-Line Survey (JELS), a JWST imaging programme
    exploiting the wavelength coverage and sensitivity of the Near-Infrared Camera
    (NIRCam) to extend narrow-band rest-optical emission-line selection into the Epoch
    of Reionization (EoR) for the first time, and to enable unique studies of the
    resolved ionized gas morphology in individual galaxies across cosmic history.
    The primary JELS observations comprise ∼ 4.7 μm narrow-band imaging over ∼ 63
    arcmin2 designed to enable selection of H α emitters at z ∼ 6.1 and a host of
    novel emission-line samples, including [O III] (z ∼ 8.3) and Paschen α/β (z ∼
    1.5/2.8). For the F466N/F470N narrow-band observations, the emission-line sensitivities
    achieved are up to ∼ 2× more sensitive than current slitless spectroscopy surveys
    (5σ limits of 0.8–1.2×10−18 erg s−1cm−2), corresponding to unobscured H α star
    formation rates (SFRs) of 0.9–1.3 M yr−1 at z ∼ 6.1, extending emission-line selections
    in the EoR to fainter populations. Simultaneously, JELS also adds F200W broad-band
    and F212N narrow-band imaging (H α at z ∼ 2.23) that probes SFRs  5× fainter than
    previous ground-based narrow-band studies (∼ 0.2 M yr−1), offering an unprecedented
    resolved view of star formation at cosmic noon. We present the detailed JELS design,
    key data processing steps specific to the survey observations, and demonstrate
    the exceptional data quality and imaging sensitivity achieved. We then summarize
    the key scientific goals of JELS, demonstrate the precision and accuracy of the
    expected redshift and measured emission-line recovery through detailed simulations,
    and present examples of spectroscopically confirmed H α and [O III] emitters discovered
    by JELS that illustrate the novel parameter space probed.
acknowledgement: "We thank the anonymous referee for their helpful and constructive
  feedback that hassignificantly improved this manuscript. The authors also thank
  DavidCoulter and ArminRestfor allowing the inclusion of JELS targets in their director’s
  discretionary observing programme. KJD acknowledges support from the Science and
  Technology Facilities Council (STFC) through an Ernest Rutherford Fellowship (grant
  number ST/W003120/1). DJM, PNB, RK, and RJM acknowledge the support of the UK STFC
  via grant ST/V000594/1. PNB and RK are grateful for support from the UK STFC via
  grant ST/Y000951/1. RKC was funded by support for programme #02321, provided by
  NASA through a grant from the Space Telescope Science Institute,\r\nwhich is operated
  by the Association of Universities for Research in Astronomy, Inc., under NASA contract
  NAS5-03127. RKC is grateful for support from the Leverhulme Trust via the Leverhulme
  Early Career Fellowship.JSD acknowledgesthe support of the Royal Society via a Royal
  Society Research Professorship. CLH acknowledges support from the Leverhulme Trust
  through an Early Career Research Fellowship and also acknowledge support from the
  Oxford\r\nHintze Centre for Astrophysical Surveys which is funded through generous
  support from the Hintze Family Charitable Foundation. EI gratefully acknowledge
  financial support from ANID –MILENIO – NCN2024 112 and ANID FONDECYT Regular 1221846.
  AMS and IRS acknowledge support from the STFC via grant ST/X001075/1.This work was
  initiated in part at Aspen Center for Physics, which is supported by National Science
  Foundation grant PHY-2210452."
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: K. J.
  full_name: Duncan, K. J.
  last_name: Duncan
- first_name: D. J.
  full_name: Mcleod, D. J.
  last_name: Mcleod
- first_name: P. N.
  full_name: Best, P. N.
  last_name: Best
- first_name: C. A.
  full_name: Pirie, C. A.
  last_name: Pirie
- first_name: M.
  full_name: Clausen, M.
  last_name: Clausen
- first_name: R. K.
  full_name: Cochrane, R. K.
  last_name: Cochrane
- first_name: J. S.
  full_name: Dunlop, J. S.
  last_name: Dunlop
- first_name: S. R.
  full_name: Flury, S. R.
  last_name: Flury
- first_name: J. E.
  full_name: Geach, J. E.
  last_name: Geach
- first_name: N. A.
  full_name: Grogin, N. A.
  last_name: Grogin
- first_name: C. L.
  full_name: Hale, C. L.
  last_name: Hale
- first_name: E.
  full_name: Ibar, E.
  last_name: Ibar
- first_name: R.
  full_name: Kondapally, R.
  last_name: Kondapally
- first_name: Zefeng
  full_name: Li, Zefeng
  last_name: Li
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: R. J.
  full_name: Mclure, R. J.
  last_name: Mclure
- first_name: Luis
  full_name: Ossa-Fuentes, Luis
  last_name: Ossa-Fuentes
- first_name: A. L.
  full_name: Patrick, A. L.
  last_name: Patrick
- first_name: Ian
  full_name: Smail, Ian
  last_name: Smail
- first_name: D.
  full_name: Sobral, D.
  last_name: Sobral
- first_name: H. M.O.
  full_name: Stephenson, H. M.O.
  last_name: Stephenson
- first_name: J. P.
  full_name: Stott, J. P.
  last_name: Stott
- first_name: A. M.
  full_name: Swinbank, A. M.
  last_name: Swinbank
citation:
  ama: 'Duncan KJ, Mcleod DJ, Best PN, et al. The JWST Emission-Line Survey: Extending
    rest-optical narrow-band emission-line selection into the Epoch of Reionization.
    <i>Monthly Notices of the Royal Astronomical Society</i>. 2025;541(2):1329-1347.
    doi:<a href="https://doi.org/10.1093/mnras/staf1061">10.1093/mnras/staf1061</a>'
  apa: 'Duncan, K. J., Mcleod, D. J., Best, P. N., Pirie, C. A., Clausen, M., Cochrane,
    R. K., … Swinbank, A. M. (2025). The JWST Emission-Line Survey: Extending rest-optical
    narrow-band emission-line selection into the Epoch of Reionization. <i>Monthly
    Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/staf1061">https://doi.org/10.1093/mnras/staf1061</a>'
  chicago: 'Duncan, K. J., D. J. Mcleod, P. N. Best, C. A. Pirie, M. Clausen, R. K.
    Cochrane, J. S. Dunlop, et al. “The JWST Emission-Line Survey: Extending Rest-Optical
    Narrow-Band Emission-Line Selection into the Epoch of Reionization.” <i>Monthly
    Notices of the Royal Astronomical Society</i>. Oxford University Press, 2025.
    <a href="https://doi.org/10.1093/mnras/staf1061">https://doi.org/10.1093/mnras/staf1061</a>.'
  ieee: 'K. J. Duncan <i>et al.</i>, “The JWST Emission-Line Survey: Extending rest-optical
    narrow-band emission-line selection into the Epoch of Reionization,” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 541, no. 2. Oxford University
    Press, pp. 1329–1347, 2025.'
  ista: 'Duncan KJ, Mcleod DJ, Best PN, Pirie CA, Clausen M, Cochrane RK, Dunlop JS,
    Flury SR, Geach JE, Grogin NA, Hale CL, Ibar E, Kondapally R, Li Z, Matthee JJ,
    Mclure RJ, Ossa-Fuentes L, Patrick AL, Smail I, Sobral D, Stephenson HMO, Stott
    JP, Swinbank AM. 2025. The JWST Emission-Line Survey: Extending rest-optical narrow-band
    emission-line selection into the Epoch of Reionization. Monthly Notices of the
    Royal Astronomical Society. 541(2), 1329–1347.'
  mla: 'Duncan, K. J., et al. “The JWST Emission-Line Survey: Extending Rest-Optical
    Narrow-Band Emission-Line Selection into the Epoch of Reionization.” <i>Monthly
    Notices of the Royal Astronomical Society</i>, vol. 541, no. 2, Oxford University
    Press, 2025, pp. 1329–47, doi:<a href="https://doi.org/10.1093/mnras/staf1061">10.1093/mnras/staf1061</a>.'
  short: K.J. Duncan, D.J. Mcleod, P.N. Best, C.A. Pirie, M. Clausen, R.K. Cochrane,
    J.S. Dunlop, S.R. Flury, J.E. Geach, N.A. Grogin, C.L. Hale, E. Ibar, R. Kondapally,
    Z. Li, J.J. Matthee, R.J. Mclure, L. Ossa-Fuentes, A.L. Patrick, I. Smail, D.
    Sobral, H.M.O. Stephenson, J.P. Stott, A.M. Swinbank, Monthly Notices of the Royal
    Astronomical Society 541 (2025) 1329–1347.
date_created: 2025-07-20T22:02:00Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2025-09-30T14:03:01Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1093/mnras/staf1061
external_id:
  arxiv:
  - '2410.09000'
  isi:
  - '001527085900001'
file:
- access_level: open_access
  checksum: abedbbce98d448f374dc922dad9133fc
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  creator: dernst
  date_created: 2025-07-22T07:02:02Z
  date_updated: 2025-07-22T07:02:02Z
  file_id: '20063'
  file_name: 2025_MonthlyNoticesRAS_Duncan.pdf
  file_size: 4451937
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T07:02:02Z
has_accepted_license: '1'
intvolume: '       541'
isi: 1
issue: '2'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 1329-1347
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The JWST Emission-Line Survey: Extending rest-optical narrow-band emission-line
  selection into the Epoch of Reionization'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 541
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '20029'
abstract:
- lang: eng
  text: Vacuolar acidification is crucial for the homeostasis of intracellular pH
    and the recycling of proteins and nutrients in cells, thereby playing important
    roles in various physiological processes related to vacuolar function. The key
    factors regulating vacuolar acidification and underlying mechanisms remain unclear.
    Here, we report that Arabidopsis phospholipase Dζ2 (PLDζ2) promotes the acidification
    of the vacuolar lumen to stimulate autophagic degradation under phosphorus deficiency.
    The pldζ2 mutant massively accumulates autophagic structures while exhibiting
    premature leaf senescence under nutrient starvation. Impaired autophagic flux,
    lytic vacuole morphology, and lytic degradation in pldζ2 indicate that PLDζ2 regulates
    autophagy by affecting the vacuolar function. PLDζ2 locates in both tonoplast
    and cytoplasm. Genetic, structural, and biochemical studies demonstrate that PLDζ2
    directly interacts with vacuolar-type ATPase (V-ATPase) subunit D (VATD) to promote
    vacuolar acidification and autophagy under phosphorus starvation. These findings
    reveal the importance of V-ATPase and vacuolar pH in autophagic activity and provide
    clues in elucidating the regulatory mechanism of vacuolar acidification.
acknowledgement: The study was supported by National Natural Science Foundation of
  China (NSFC, 92354301, 32230011, 32200274, and 91954206). The computations were
  run on the Siyuan-1 cluster supported by the Center for High-Performance Computing
  at Shanghai Jiao Tong University.
article_number: '116024'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Bin
  full_name: Guan, Bin
  id: 56aad729-cca2-11ed-a45a-9b4138991a48
  last_name: Guan
- first_name: Ke Xuan
  full_name: Xie, Ke Xuan
  last_name: Xie
- first_name: Xin Qiao
  full_name: Du, Xin Qiao
  last_name: Du
- first_name: Yu Xuan
  full_name: Bai, Yu Xuan
  last_name: Bai
- first_name: Peng Chao
  full_name: Hao, Peng Chao
  last_name: Hao
- first_name: Wen Hui
  full_name: Lin, Wen Hui
  last_name: Lin
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Hong Wei
  full_name: Xue, Hong Wei
  last_name: Xue
citation:
  ama: Guan B, Xie KX, Du XQ, et al. Arabidopsis phospholipase Dζ2 facilitates vacuolar
    acidification and autophagy under phosphorus starvation by interacting with VATD.
    <i>Cell Reports</i>. 2025;44(7). doi:<a href="https://doi.org/10.1016/j.celrep.2025.116024">10.1016/j.celrep.2025.116024</a>
  apa: Guan, B., Xie, K. X., Du, X. Q., Bai, Y. X., Hao, P. C., Lin, W. H., … Xue,
    H. W. (2025). Arabidopsis phospholipase Dζ2 facilitates vacuolar acidification
    and autophagy under phosphorus starvation by interacting with VATD. <i>Cell Reports</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.celrep.2025.116024">https://doi.org/10.1016/j.celrep.2025.116024</a>
  chicago: Guan, Bin, Ke Xuan Xie, Xin Qiao Du, Yu Xuan Bai, Peng Chao Hao, Wen Hui
    Lin, Jiří Friml, and Hong Wei Xue. “Arabidopsis Phospholipase Dζ2 Facilitates
    Vacuolar Acidification and Autophagy under Phosphorus Starvation by Interacting
    with VATD.” <i>Cell Reports</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.celrep.2025.116024">https://doi.org/10.1016/j.celrep.2025.116024</a>.
  ieee: B. Guan <i>et al.</i>, “Arabidopsis phospholipase Dζ2 facilitates vacuolar
    acidification and autophagy under phosphorus starvation by interacting with VATD,”
    <i>Cell Reports</i>, vol. 44, no. 7. Elsevier, 2025.
  ista: Guan B, Xie KX, Du XQ, Bai YX, Hao PC, Lin WH, Friml J, Xue HW. 2025. Arabidopsis
    phospholipase Dζ2 facilitates vacuolar acidification and autophagy under phosphorus
    starvation by interacting with VATD. Cell Reports. 44(7), 116024.
  mla: Guan, Bin, et al. “Arabidopsis Phospholipase Dζ2 Facilitates Vacuolar Acidification
    and Autophagy under Phosphorus Starvation by Interacting with VATD.” <i>Cell Reports</i>,
    vol. 44, no. 7, 116024, Elsevier, 2025, doi:<a href="https://doi.org/10.1016/j.celrep.2025.116024">10.1016/j.celrep.2025.116024</a>.
  short: B. Guan, K.X. Xie, X.Q. Du, Y.X. Bai, P.C. Hao, W.H. Lin, J. Friml, H.W.
    Xue, Cell Reports 44 (2025).
date_created: 2025-07-20T22:02:01Z
date_published: 2025-07-22T00:00:00Z
date_updated: 2025-09-30T14:05:28Z
day: '22'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.celrep.2025.116024
external_id:
  isi:
  - '001533244800001'
  pmid:
  - '40668679'
file:
- access_level: open_access
  checksum: ee03deee47a084b0295251dc49470ad4
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T08:52:17Z
  date_updated: 2025-07-22T08:52:17Z
  file_id: '20067'
  file_name: 2025_CellReports_Guan.pdf
  file_size: 37708120
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T08:52:17Z
has_accepted_license: '1'
intvolume: '        44'
isi: 1
issue: '7'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cell Reports
publication_identifier:
  eissn:
  - 2211-1247
  issn:
  - 2639-1856
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Arabidopsis phospholipase Dζ2 facilitates vacuolar acidification and autophagy
  under phosphorus starvation by interacting with VATD
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 44
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20030'
abstract:
- lang: eng
  text: We report the discovery of a Lyα emitter (LAE) candidate in the immediate
    foreground of the quasar PSO J158-14 at zQSO = 6.0685 at a projected distance
    ∼29 pkpc that is associated with an extremely metal-poor absorption system. This
    system was found in archival observations of the quasar field with the Very Large
    Telescope (VLT)/Multi-Unit Spectroscopic Explorer (MUSE) and was previously missed
    in searches of absorption systems using quasar absorption line spectroscopy, as
    it imparts no detectable metal absorption lines on the background quasar spectrum.
    The detected Lyα emission line at a redshift of zLAE = 6.0323 is well aligned
    with the outer edge of the quasar’s proximity zone and can plausibly cause its
    observed damping wing if it is associated with a proximate subdamped Lyα absorption
    system with a column density of log Nhi/cm^-2 19.7. A >10 hr medium-resolution
    spectrum of the quasar observed with the Magellan/Folded-port InfraRed Echellette
    (FIRE) and VLT/X-Shooter spectrographs reveals a metallicity constraint of [Z/H]
    < −3. Such low metallicity makes this system an extremely metal-poor galaxy candidate
    and provides an exciting site to study possible signatures of Population III stars.
acknowledgement: "We thank the referee for the feedback and suggestions that greatly
  improved the quality of this manuscript. We would like to thank Carlos Contreras,
  Matías Díaz, Carla Fuentes, Mauricio Martínez, Alberto Pastén, Roger Leiton, Hugo
  Rivera, and Gabriel Prieto for their help and support during the Magellan/FIRE observations.
  We would also like to thank Rongmon Bordoloi for helpful discussions. R.A.M. acknowledges
  support from the Swiss National Science Foundation (SNSF) through project grant
  200020_207349. This Letter includes data gathered with the 6.5 m Magellan Telescopes
  located at Las Campanas Observatory, Chile.\r\nBased on observations collected at
  the European Southern Observatory under ESO programs 106.215A and 096.A-0418.\r\n\r\nThe
  HST data presented in this Letter were obtained from the Mikulski Archive for Space
  Telescopes (MAST) at the Space Telescope Science Institute. The observations analyzed
  in this work can be accessed via doi:10.17909/gxmz-zd87."
article_number: L33
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Dominika
  full_name: Ďurovčíková, Dominika
  last_name: Ďurovčíková
- first_name: Anna Christina
  full_name: Eilers, Anna Christina
  last_name: Eilers
- first_name: Robert A.
  full_name: Simcoe, Robert A.
  last_name: Simcoe
- first_name: Louise
  full_name: Welsh, Louise
  last_name: Welsh
- first_name: Romain A.
  full_name: Meyer, Romain A.
  last_name: Meyer
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Emma V.
  full_name: Ryan-Weber, Emma V.
  last_name: Ryan-Weber
- first_name: Minghao
  full_name: Yue, Minghao
  last_name: Yue
- first_name: Harley
  full_name: Katz, Harley
  last_name: Katz
- first_name: Sindhu
  full_name: Satyavolu, Sindhu
  last_name: Satyavolu
- first_name: George
  full_name: Becker, George
  last_name: Becker
- first_name: Frederick B.
  full_name: Davies, Frederick B.
  last_name: Davies
- first_name: Emanuele Paolo
  full_name: Farina, Emanuele Paolo
  last_name: Farina
citation:
  ama: Ďurovčíková D, Eilers AC, Simcoe RA, et al. An extremely metal-poor Lyα emitter
    candidate at z = 6 revealed through absorption spectroscopy. <i>The Astrophysical
    Journal Letters</i>. 2025;987(2). doi:<a href="https://doi.org/10.3847/2041-8213/ade71c">10.3847/2041-8213/ade71c</a>
  apa: Ďurovčíková, D., Eilers, A. C., Simcoe, R. A., Welsh, L., Meyer, R. A., Matthee,
    J. J., … Farina, E. P. (2025). An extremely metal-poor Lyα emitter candidate at
    z = 6 revealed through absorption spectroscopy. <i>The Astrophysical Journal Letters</i>.
    IOP Publishing. <a href="https://doi.org/10.3847/2041-8213/ade71c">https://doi.org/10.3847/2041-8213/ade71c</a>
  chicago: Ďurovčíková, Dominika, Anna Christina Eilers, Robert A. Simcoe, Louise
    Welsh, Romain A. Meyer, Jorryt J Matthee, Emma V. Ryan-Weber, et al. “An Extremely
    Metal-Poor Lyα Emitter Candidate at z = 6 Revealed through Absorption Spectroscopy.”
    <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2025. <a href="https://doi.org/10.3847/2041-8213/ade71c">https://doi.org/10.3847/2041-8213/ade71c</a>.
  ieee: D. Ďurovčíková <i>et al.</i>, “An extremely metal-poor Lyα emitter candidate
    at z = 6 revealed through absorption spectroscopy,” <i>The Astrophysical Journal
    Letters</i>, vol. 987, no. 2. IOP Publishing, 2025.
  ista: Ďurovčíková D, Eilers AC, Simcoe RA, Welsh L, Meyer RA, Matthee JJ, Ryan-Weber
    EV, Yue M, Katz H, Satyavolu S, Becker G, Davies FB, Farina EP. 2025. An extremely
    metal-poor Lyα emitter candidate at z = 6 revealed through absorption spectroscopy.
    The Astrophysical Journal Letters. 987(2), L33.
  mla: Ďurovčíková, Dominika, et al. “An Extremely Metal-Poor Lyα Emitter Candidate
    at z = 6 Revealed through Absorption Spectroscopy.” <i>The Astrophysical Journal
    Letters</i>, vol. 987, no. 2, L33, IOP Publishing, 2025, doi:<a href="https://doi.org/10.3847/2041-8213/ade71c">10.3847/2041-8213/ade71c</a>.
  short: D. Ďurovčíková, A.C. Eilers, R.A. Simcoe, L. Welsh, R.A. Meyer, J.J. Matthee,
    E.V. Ryan-Weber, M. Yue, H. Katz, S. Satyavolu, G. Becker, F.B. Davies, E.P. Farina,
    The Astrophysical Journal Letters 987 (2025).
date_created: 2025-07-20T22:02:01Z
date_published: 2025-07-10T00:00:00Z
date_updated: 2026-02-16T12:44:23Z
day: '10'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/2041-8213/ade71c
external_id:
  arxiv:
  - '2505.01499'
  isi:
  - '001524847100001'
file:
- access_level: open_access
  checksum: 75d0c08514209fc6e3078fdec8e815a2
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T08:38:14Z
  date_updated: 2025-07-22T08:38:14Z
  file_id: '20066'
  file_name: 2025_AstrophysicalJourLetters_Durovcikova.pdf
  file_size: 6453728
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T08:38:14Z
has_accepted_license: '1'
intvolume: '       987'
isi: 1
issue: '2'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal Letters
publication_identifier:
  eissn:
  - 2041-8213
  issn:
  - 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: An extremely metal-poor Lyα emitter candidate at z = 6 revealed through absorption
  spectroscopy
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 987
year: '2025'
...
---
OA_type: closed access
_id: '20031'
abstract:
- lang: eng
  text: The central vacuole is a multifunctional organelle with the most significant
    occupancy in a differentiated plant cell. Plants depend on the function of the
    vacuole for critical development, growth, and environmental responses. As the
    cell expands, the vacuole changes shape and size, increasing its membrane and
    luminal content. The set of these events is called the vacuolar configuration
    process, which has not been well described. Our research highlights the impact
    of plasma membrane internalization on vacuole morphology during the vacuolar configuration
    process. We observed a direct correlation between differential endocytosis rates
    and the enrichment of vacuolar membranous structures. Chemical and genetic interference
    with clathrin-mediated endocytosis (CME) revealed that it is required for the
    vacuolar configuration of growing root cells. The contribution of CME to the vacuole
    configuration process co-occurs with the induction of post-trans-Golgi network
    (TGN)/early endosome (EE) trafficking with the participation of the Rab GTPases
    ARA6 and ARA7. Our results show that the CME plays an active role during vacuole
    configuration, most probably carrying the material that allows the establishment
    of the vacuole in elongating cells. Since membrane trafficking through the EE/TGN
    is required to reach the vacuole, additional players must be defined.
acknowledgement: "This research was supported by FONDECYT grants 1170950 and 1211311
  and by ANID PhD fellowship 2020-21201663 to PhD student CO-N. The microscopes used
  in this work were funded by grants FONDEQUIP #EQM 140019 and #EQM12-0003 at the
  Advanced Microscopy Unit of the Biology Department, Faculty of Science, University
  of Chile.\r\nWe thank Jiri Friml for donating the XVE»AUXILIN-LIKE2 (AX2) line to
  support our research. We wish to acknowledge the active and helpful discussion of
  all the members of the LNM team and the Plant Molecular Biology Centre at Universidad
  de Chile."
article_processing_charge: No
article_type: original
author:
- first_name: Claudio
  full_name: Osorio-Navarro, Claudio
  last_name: Osorio-Navarro
- first_name: Gabriel
  full_name: Neira-Valenzuela, Gabriel
  last_name: Neira-Valenzuela
- first_name: Paula
  full_name: Sierra, Paula
  last_name: Sierra
- first_name: Maciek
  full_name: Adamowski, Maciek
  id: 45F536D2-F248-11E8-B48F-1D18A9856A87
  last_name: Adamowski
  orcid: 0000-0001-6463-5257
- first_name: Jorge
  full_name: Toledo, Jorge
  last_name: Toledo
- first_name: Lorena
  full_name: Norambuena, Lorena
  last_name: Norambuena
citation:
  ama: Osorio-Navarro C, Neira-Valenzuela G, Sierra P, Adamowski M, Toledo J, Norambuena
    L. The configuration of the vacuole is driven by clathrin-mediated trafficking
    in root cells of Arabidopsis thaliana. <i>Journal of Experimental Botany</i>.
    2025;76(10):2700-2714. doi:<a href="https://doi.org/10.1093/jxb/eraf084">10.1093/jxb/eraf084</a>
  apa: Osorio-Navarro, C., Neira-Valenzuela, G., Sierra, P., Adamowski, M., Toledo,
    J., &#38; Norambuena, L. (2025). The configuration of the vacuole is driven by
    clathrin-mediated trafficking in root cells of Arabidopsis thaliana. <i>Journal
    of Experimental Botany</i>. Oxford University Press. <a href="https://doi.org/10.1093/jxb/eraf084">https://doi.org/10.1093/jxb/eraf084</a>
  chicago: Osorio-Navarro, Claudio, Gabriel Neira-Valenzuela, Paula Sierra, Maciek
    Adamowski, Jorge Toledo, and Lorena Norambuena. “The Configuration of the Vacuole
    Is Driven by Clathrin-Mediated Trafficking in Root Cells of Arabidopsis Thaliana.”
    <i>Journal of Experimental Botany</i>. Oxford University Press, 2025. <a href="https://doi.org/10.1093/jxb/eraf084">https://doi.org/10.1093/jxb/eraf084</a>.
  ieee: C. Osorio-Navarro, G. Neira-Valenzuela, P. Sierra, M. Adamowski, J. Toledo,
    and L. Norambuena, “The configuration of the vacuole is driven by clathrin-mediated
    trafficking in root cells of Arabidopsis thaliana,” <i>Journal of Experimental
    Botany</i>, vol. 76, no. 10. Oxford University Press, pp. 2700–2714, 2025.
  ista: Osorio-Navarro C, Neira-Valenzuela G, Sierra P, Adamowski M, Toledo J, Norambuena
    L. 2025. The configuration of the vacuole is driven by clathrin-mediated trafficking
    in root cells of Arabidopsis thaliana. Journal of Experimental Botany. 76(10),
    2700–2714.
  mla: Osorio-Navarro, Claudio, et al. “The Configuration of the Vacuole Is Driven
    by Clathrin-Mediated Trafficking in Root Cells of Arabidopsis Thaliana.” <i>Journal
    of Experimental Botany</i>, vol. 76, no. 10, Oxford University Press, 2025, pp.
    2700–14, doi:<a href="https://doi.org/10.1093/jxb/eraf084">10.1093/jxb/eraf084</a>.
  short: C. Osorio-Navarro, G. Neira-Valenzuela, P. Sierra, M. Adamowski, J. Toledo,
    L. Norambuena, Journal of Experimental Botany 76 (2025) 2700–2714.
date_created: 2025-07-20T22:02:01Z
date_published: 2025-07-02T00:00:00Z
date_updated: 2025-09-30T14:04:16Z
day: '02'
department:
- _id: JiFr
doi: 10.1093/jxb/eraf084
external_id:
  isi:
  - '001482869200001'
  pmid:
  - '40056424'
intvolume: '        76'
isi: 1
issue: '10'
language:
- iso: eng
month: '07'
oa_version: None
page: 2700-2714
pmid: 1
publication: Journal of Experimental Botany
publication_identifier:
  eissn:
  - 1460-2431
  issn:
  - 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The configuration of the vacuole is driven by clathrin-mediated trafficking
  in root cells of Arabidopsis thaliana
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 76
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20032'
abstract:
- lang: eng
  text: We propose Scalable Mechanistic Neural Network (S-MNN), an enhanced neural
    network framework designed for scientific machine learning applications involving
    long temporal sequences. By reformulating the original Mechanistic Neural Network
    (MNN) (Pervez et al., 2024), we reduce the computational time and space complexities
    from cubic and quadratic with respect to the sequence length, respectively, to
    linear. This significant improvement enables efficient modeling of long-term dynamics
    without sacrificing accuracy or interpretability. Extensive experiments demonstrate
    that S-MNN matches the original MNN in precision while substantially reducing
    computational resources. Consequently, S-MNN can drop-in replace the original
    MNN in applications, providing a practical and efficient tool for integrating
    mechanistic bottlenecks into neural network models of complex dynamical systems.
    Source code is available at https://github.com/IST-DASLab/ScalableMNN.
article_processing_charge: No
arxiv: 1
author:
- first_name: Jiale
  full_name: Chen, Jiale
  id: 4d0a9064-1ff6-11ee-9fa6-ec046c604785
  last_name: Chen
  orcid: 0000-0001-5337-5875
- first_name: Dingling
  full_name: Yao, Dingling
  id: d3e02e50-48a8-11ee-8f62-c108061797fa
  last_name: Yao
- first_name: Adeel A
  full_name: Pervez, Adeel A
  id: fca6d90c-d47f-11ee-bc87-93ff51604981
  last_name: Pervez
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
citation:
  ama: 'Chen J, Yao D, Pervez AA, Alistarh D-A, Locatello F. Scalable mechanistic
    neural networks. In: <i>13th International Conference on Learning Representations</i>.
    ICLR; 2025:63716-63737.'
  apa: 'Chen, J., Yao, D., Pervez, A. A., Alistarh, D.-A., &#38; Locatello, F. (2025).
    Scalable mechanistic neural networks. In <i>13th International Conference on Learning
    Representations</i> (pp. 63716–63737). Singapore, Singapore: ICLR.'
  chicago: Chen, Jiale, Dingling Yao, Adeel A Pervez, Dan-Adrian Alistarh, and Francesco
    Locatello. “Scalable Mechanistic Neural Networks.” In <i>13th International Conference
    on Learning Representations</i>, 63716–37. ICLR, 2025.
  ieee: J. Chen, D. Yao, A. A. Pervez, D.-A. Alistarh, and F. Locatello, “Scalable
    mechanistic neural networks,” in <i>13th International Conference on Learning
    Representations</i>, Singapore, Singapore, 2025, pp. 63716–63737.
  ista: 'Chen J, Yao D, Pervez AA, Alistarh D-A, Locatello F. 2025. Scalable mechanistic
    neural networks. 13th International Conference on Learning Representations. ICLR:
    International Conference on Learning Representations, 63716–63737.'
  mla: Chen, Jiale, et al. “Scalable Mechanistic Neural Networks.” <i>13th International
    Conference on Learning Representations</i>, ICLR, 2025, pp. 63716–37.
  short: J. Chen, D. Yao, A.A. Pervez, D.-A. Alistarh, F. Locatello, in:, 13th International
    Conference on Learning Representations, ICLR, 2025, pp. 63716–63737.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
corr_author: '1'
date_created: 2025-07-20T22:02:01Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:03:11Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
- _id: FrLo
external_id:
  arxiv:
  - '2410.06074'
file:
- access_level: open_access
  checksum: 64cfdb12ae3e4e8ba57b1403e1066776
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T07:58:22Z
  date_updated: 2025-07-22T07:58:22Z
  file_id: '20065'
  file_name: 2025_ICLR_Chen.pdf
  file_size: 732745
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T07:58:22Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 63716-63737
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/IST-DASLab/ScalableMNN
scopus_import: '1'
status: public
title: Scalable mechanistic neural networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20033'
abstract:
- lang: eng
  text: 'A growing number of machine learning scenarios rely on knowledge distillation
    where one uses the output of a surrogate model as labels to supervise the training
    of a target model. In this work, we provide a sharp characterization of this process
    for ridgeless, high-dimensional regression, under two settings: (i) model shift,
    where the surrogate model is arbitrary, and (ii) distribution shift, where the
    surrogate model is the solution of empirical risk minimization with out-of-distribution
    data. In both cases, we characterize the precise risk of the target model through
    non-asymptotic bounds in terms of sample size and data distribution under mild
    conditions. As a consequence, we identify the form of the optimal surrogate model,
    which reveals the benefits and limitations of discarding weak features in a data-dependent
    fashion. In the context of weak-to-strong (W2S) generalization, this has the interpretation
    that (i) W2S training, with the surrogate as the weak model, can provably outperform
    training with strong labels under the same data budget, but (ii) it is unable
    to improve the data scaling law. We validate our results on numerical experiments
    both on ridgeless regression and on neural network architectures.'
acknowledgement: M.E.I., H.A.G., E.O.T., S.O. are supported by the NSF grants CCF-2046816,
  CCF-2403075, the Office of Naval Research grant N000142412289, an OpenAI Agentic
  AI Systems grant, and gifts by Open Philanthropy and Google Research. M. M. is funded
  by the European Union (ERC, INF2, project number 101161364). Views and opinions
  expressed are however those of the author(s) only and do not necessarily reflect
  those of the European Union or the European Research Council Executive Agency. Neither
  the European Union nor the granting authority can be held responsible for them.
article_processing_charge: No
arxiv: 1
author:
- first_name: M.
  full_name: Emrullah Ildiz, M.
  last_name: Emrullah Ildiz
- first_name: Halil Alperen
  full_name: Gozeten, Halil Alperen
  last_name: Gozeten
- first_name: Ege Onur
  full_name: Taga, Ege Onur
  last_name: Taga
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Samet
  full_name: Oymak, Samet
  last_name: Oymak
citation:
  ama: 'Emrullah Ildiz M, Gozeten HA, Taga EO, Mondelli M, Oymak S. High-dimensional
    analysis of knowledge distillation: Weak-to-Strong generalization and scaling
    laws. In: <i>13th International Conference on Learning Representations</i>. ICLR;
    2025:2967-3006.'
  apa: 'Emrullah Ildiz, M., Gozeten, H. A., Taga, E. O., Mondelli, M., &#38; Oymak,
    S. (2025). High-dimensional analysis of knowledge distillation: Weak-to-Strong
    generalization and scaling laws. In <i>13th International Conference on Learning
    Representations</i> (pp. 2967–3006). Singapore, Singapore: ICLR.'
  chicago: 'Emrullah Ildiz, M., Halil Alperen Gozeten, Ege Onur Taga, Marco Mondelli,
    and Samet Oymak. “High-Dimensional Analysis of Knowledge Distillation: Weak-to-Strong
    Generalization and Scaling Laws.” In <i>13th International Conference on Learning
    Representations</i>, 2967–3006. ICLR, 2025.'
  ieee: 'M. Emrullah Ildiz, H. A. Gozeten, E. O. Taga, M. Mondelli, and S. Oymak,
    “High-dimensional analysis of knowledge distillation: Weak-to-Strong generalization
    and scaling laws,” in <i>13th International Conference on Learning Representations</i>,
    Singapore, Singapore, 2025, pp. 2967–3006.'
  ista: 'Emrullah Ildiz M, Gozeten HA, Taga EO, Mondelli M, Oymak S. 2025. High-dimensional
    analysis of knowledge distillation: Weak-to-Strong generalization and scaling
    laws. 13th International Conference on Learning Representations. ICLR: International
    Conference on Learning Representations, 2967–3006.'
  mla: 'Emrullah Ildiz, M., et al. “High-Dimensional Analysis of Knowledge Distillation:
    Weak-to-Strong Generalization and Scaling Laws.” <i>13th International Conference
    on Learning Representations</i>, ICLR, 2025, pp. 2967–3006.'
  short: M. Emrullah Ildiz, H.A. Gozeten, E.O. Taga, M. Mondelli, S. Oymak, in:, 13th
    International Conference on Learning Representations, ICLR, 2025, pp. 2967–3006.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
date_created: 2025-07-20T22:02:02Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:33:58Z
day: '01'
ddc:
- '000'
department:
- _id: MaMo
external_id:
  arxiv:
  - '2410.18837'
file:
- access_level: open_access
  checksum: 5a38b093ebb4ee4eb662ea142621a5ca
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:32:38Z
  date_updated: 2025-08-04T08:32:38Z
  file_id: '20112'
  file_name: 2025_ICLR_Ildiz.pdf
  file_size: 528171
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:32:38Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 2967-3006
project:
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
  grant_number: '101161364'
  name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'High-dimensional analysis of knowledge distillation: Weak-to-Strong generalization
  and scaling laws'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20034'
abstract:
- lang: eng
  text: We introduce LDAdam, a memory-efficient optimizer for training large models,
    that performs adaptive optimization steps within lower dimensional subspaces,
    while consistently exploring the full parameter space during training. This strategy
    keeps the optimizer's memory footprint to a fraction of the model size. LDAdam
    relies on a new projection-aware update rule for the optimizer states that allows
    for transitioning between subspaces, i.e., estimation of the statistics of the
    projected gradients. To mitigate the errors due to low-rank projection, LDAdam
    integrates a new generalized error feedback mechanism, which explicitly accounts
    for both gradient and optimizer state compression. We prove the convergence of
    LDAdam under standard assumptions, and provide empirical evidence that LDAdam
    allows for efficient fine-tuning and pre-training of language models.
article_processing_charge: No
arxiv: 1
author:
- first_name: Thomas
  full_name: Robert, Thomas
  last_name: Robert
- first_name: Mher
  full_name: Safaryan, Mher
  id: dd546b39-0804-11ed-9c55-ef075c39778d
  last_name: Safaryan
- first_name: Ionut-Vlad
  full_name: Modoranu, Ionut-Vlad
  id: 449f7a18-f128-11eb-9611-9b430c0c6333
  last_name: Modoranu
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Robert T, Safaryan M, Modoranu I-V, Alistarh D-A. LDAdam: Adaptive optimization
    from low-dimensional gradient statistics. In: <i>13th International Conference
    on Learning Representations</i>. ICLR; 2025:101877-101913.'
  apa: 'Robert, T., Safaryan, M., Modoranu, I.-V., &#38; Alistarh, D.-A. (2025). LDAdam:
    Adaptive optimization from low-dimensional gradient statistics. In <i>13th International
    Conference on Learning Representations</i> (pp. 101877–101913). Singapore, Singapore:
    ICLR.'
  chicago: 'Robert, Thomas, Mher Safaryan, Ionut-Vlad Modoranu, and Dan-Adrian Alistarh.
    “LDAdam: Adaptive Optimization from Low-Dimensional Gradient Statistics.” In <i>13th
    International Conference on Learning Representations</i>, 101877–913. ICLR, 2025.'
  ieee: 'T. Robert, M. Safaryan, I.-V. Modoranu, and D.-A. Alistarh, “LDAdam: Adaptive
    optimization from low-dimensional gradient statistics,” in <i>13th International
    Conference on Learning Representations</i>, Singapore, Singapore, 2025, pp. 101877–101913.'
  ista: 'Robert T, Safaryan M, Modoranu I-V, Alistarh D-A. 2025. LDAdam: Adaptive
    optimization from low-dimensional gradient statistics. 13th International Conference
    on Learning Representations. ICLR: International Conference on Learning Representations,
    101877–101913.'
  mla: 'Robert, Thomas, et al. “LDAdam: Adaptive Optimization from Low-Dimensional
    Gradient Statistics.” <i>13th International Conference on Learning Representations</i>,
    ICLR, 2025, pp. 101877–913.'
  short: T. Robert, M. Safaryan, I.-V. Modoranu, D.-A. Alistarh, in:, 13th International
    Conference on Learning Representations, ICLR, 2025, pp. 101877–101913.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
corr_author: '1'
date_created: 2025-07-20T22:02:02Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:41:10Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2410.16103'
file:
- access_level: open_access
  checksum: 9327d82569358d7bf1c3ec1a9952e721
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:39:51Z
  date_updated: 2025-08-04T08:39:51Z
  file_id: '20113'
  file_name: 2025_ICLR_Robert.pdf
  file_size: 1346111
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:39:51Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 101877-101913
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/IST-DASLab/LDAdam
scopus_import: '1'
status: public
title: 'LDAdam: Adaptive optimization from low-dimensional gradient statistics'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20035'
abstract:
- lang: eng
  text: "Deep neural networks (DNNs) at convergence consistently represent the training
    data in the last layer via a geometric structure referred to as neural collapse.
    This empirical evidence has spurred a line of theoretical research aimed at proving
    the emergence of neural collapse, mostly focusing on the unconstrained features
    model. Here, the features of the penultimate layer are free variables, which makes
    the model data-agnostic and puts into question its ability to capture DNN training.
    Our work addresses the issue, moving away from unconstrained features and\r\nstudying
    DNNs that end with at least two linear layers. We first prove generic guarantees
    on neural collapse that assume (i) low training error and balancedness of linear
    layers (for within-class variability collapse), and (ii) bounded conditioning
    of the features before the linear part (for orthogonality of class-means, and
    their alignment with weight matrices). The balancedness refers to the fact that
    W⊤ℓ+1Wℓ+1 ≈ WℓW⊤ℓfor any pair of consecutive weight matrices of the linear part,
    and the bounded conditioning requires a well-behaved ratio between largest and
    smallest non-zero singular values of the features. We then show that such assumptions
    hold for gradient descent training with weight decay: (i) for networks with a
    wide first layer, we prove low training error and balancedness, and (ii) for solutions
    that are either nearly optimal or stable under large learning rates, we additionally
    prove the bounded conditioning. Taken together, our results are the first to show
    neural collapse in the end-to-end training of DNNs."
acknowledgement: M. M. and P. S. are funded by the European Union (ERC, INF2, project
  number 101161364). Views and opinions expressed are however those of the author(s)
  only and do not necessarily reflect those of the European Union or the European
  Research Council Executive Agency. Neither the European Union nor the granting authority
  can be held responsible for them.
article_processing_charge: No
arxiv: 1
author:
- first_name: Arthur
  full_name: Jacot, Arthur
  last_name: Jacot
- first_name: Peter
  full_name: Súkeník, Peter
  id: d64d6a8d-eb8e-11eb-b029-96fd216dec3c
  last_name: Súkeník
- first_name: Zihan
  full_name: Wang, Zihan
  last_name: Wang
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
citation:
  ama: 'Jacot A, Súkeník P, Wang Z, Mondelli M. Wide neural networks trained with
    weight decay provably exhibit neural collapse. In: <i>13th International Conference
    on Learning Representations</i>. ICLR; 2025:1905-1931.'
  apa: 'Jacot, A., Súkeník, P., Wang, Z., &#38; Mondelli, M. (2025). Wide neural networks
    trained with weight decay provably exhibit neural collapse. In <i>13th International
    Conference on Learning Representations</i> (pp. 1905–1931). Singapore, Singapore:
    ICLR.'
  chicago: Jacot, Arthur, Peter Súkeník, Zihan Wang, and Marco Mondelli. “Wide Neural
    Networks Trained with Weight Decay Provably Exhibit Neural Collapse.” In <i>13th
    International Conference on Learning Representations</i>, 1905–31. ICLR, 2025.
  ieee: A. Jacot, P. Súkeník, Z. Wang, and M. Mondelli, “Wide neural networks trained
    with weight decay provably exhibit neural collapse,” in <i>13th International
    Conference on Learning Representations</i>, Singapore, Singapore, 2025, pp. 1905–1931.
  ista: 'Jacot A, Súkeník P, Wang Z, Mondelli M. 2025. Wide neural networks trained
    with weight decay provably exhibit neural collapse. 13th International Conference
    on Learning Representations. ICLR: International Conference on Learning Representations,
    1905–1931.'
  mla: Jacot, Arthur, et al. “Wide Neural Networks Trained with Weight Decay Provably
    Exhibit Neural Collapse.” <i>13th International Conference on Learning Representations</i>,
    ICLR, 2025, pp. 1905–31.
  short: A. Jacot, P. Súkeník, Z. Wang, M. Mondelli, in:, 13th International Conference
    on Learning Representations, ICLR, 2025, pp. 1905–1931.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
corr_author: '1'
date_created: 2025-07-20T22:02:02Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:47:00Z
day: '01'
ddc:
- '000'
department:
- _id: MaMo
external_id:
  arxiv:
  - '2410.04887'
file:
- access_level: open_access
  checksum: 59c48c173887139647cc9839c0801136
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:45:43Z
  date_updated: 2025-08-04T08:45:43Z
  file_id: '20114'
  file_name: 2025_ICLR_Jacot.pdf
  file_size: 1337236
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:45:43Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1905-1931
project:
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
  grant_number: '101161364'
  name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
scopus_import: '1'
status: public
title: Wide neural networks trained with weight decay provably exhibit neural collapse
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20036'
abstract:
- lang: eng
  text: 'We introduce NeCo: Patch Neighbor Consistency, a novel self-supervised training
    loss that enforces patch-level nearest neighbor consistency across a student and
    teacher model. Compared to contrastive approaches that only yield binary learning
    signals, i.e. "attract" and "repel", this approach benefits from the more fine-grained
    learning signal of sorting spatially dense features relative to reference patches.
    Our method leverages differentiable sorting applied on top of pretrained representations,
    such as DINOv2-registers to bootstrap the learning signal and further improve
    upon them. This dense post-pretraining leads to superior performance across various
    models and datasets, despite requiring only 19 hours on a single GPU. This method
    generates high-quality dense feature encoders and establishes several new state-of-the-art
    results such as +2.3 % and +4.2% for non-parametric in-context semantic segmentation
    on ADE20k and Pascal VOC, +1.6% and +4.8% for linear segmentation evaluations
    on COCO-Things and -Stuff and improvements in the 3D understanding of multi-view
    consistency on SPair-71k, by more than 1.5%.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Valentinos
  full_name: Pariza, Valentinos
  last_name: Pariza
- first_name: Mohammadreza
  full_name: Salehi, Mohammadreza
  last_name: Salehi
- first_name: Gertjan
  full_name: Burghouts, Gertjan
  last_name: Burghouts
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Yuki M.
  full_name: Asano, Yuki M.
  last_name: Asano
citation:
  ama: 'Pariza V, Salehi M, Burghouts G, Locatello F, Asano YM. Near, far: Patch-ordering
    enhances vision foundation models’ scene understanding. In: <i>13th International
    Conference on Learning Representations</i>. ICLR; 2025:72303-72330.'
  apa: 'Pariza, V., Salehi, M., Burghouts, G., Locatello, F., &#38; Asano, Y. M. (2025).
    Near, far: Patch-ordering enhances vision foundation models’ scene understanding.
    In <i>13th International Conference on Learning Representations</i> (pp. 72303–72330).
    Singapore, Singapore: ICLR.'
  chicago: 'Pariza, Valentinos, Mohammadreza Salehi, Gertjan Burghouts, Francesco
    Locatello, and Yuki M. Asano. “Near, Far: Patch-Ordering Enhances Vision Foundation
    Models’ Scene Understanding.” In <i>13th International Conference on Learning
    Representations</i>, 72303–30. ICLR, 2025.'
  ieee: 'V. Pariza, M. Salehi, G. Burghouts, F. Locatello, and Y. M. Asano, “Near,
    far: Patch-ordering enhances vision foundation models’ scene understanding,” in
    <i>13th International Conference on Learning Representations</i>, Singapore, Singapore,
    2025, pp. 72303–72330.'
  ista: 'Pariza V, Salehi M, Burghouts G, Locatello F, Asano YM. 2025. Near, far:
    Patch-ordering enhances vision foundation models’ scene understanding. 13th International
    Conference on Learning Representations. ICLR: International Conference on Learning
    Representations, 72303–72330.'
  mla: 'Pariza, Valentinos, et al. “Near, Far: Patch-Ordering Enhances Vision Foundation
    Models’ Scene Understanding.” <i>13th International Conference on Learning Representations</i>,
    ICLR, 2025, pp. 72303–30.'
  short: V. Pariza, M. Salehi, G. Burghouts, F. Locatello, Y.M. Asano, in:, 13th International
    Conference on Learning Representations, ICLR, 2025, pp. 72303–72330.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
date_created: 2025-07-20T22:02:03Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:10:55Z
day: '01'
ddc:
- '000'
department:
- _id: FrLo
external_id:
  arxiv:
  - '2408.11054'
file:
- access_level: open_access
  checksum: ddbe981f3ad3f6cb6daf12c954822eb8
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:09:43Z
  date_updated: 2025-08-04T08:09:43Z
  file_id: '20109'
  file_name: 2025_ICLR_Pariza.pdf
  file_size: 37788223
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:09:43Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 72303-72330
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Near, far: Patch-ordering enhances vision foundation models'' scene understanding'
tmp:
  image: /images/cc_by.png
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  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20037'
abstract:
- lang: eng
  text: 'Disentangling polysemantic neurons is at the core of many current approaches
    to interpretability of large language models. Here we attempt to study how disentanglement
    can be used to understand performance, particularly under weight sparsity, a leading
    post-training optimization technique. We suggest a novel measure for estimating
    neuronal entanglement: the Wasserstein distance of a neuron''s output distribution
    to a Gaussian. Moreover, we show the existence of a small number of highly entangled
    "Wasserstein Neurons" in each linear layer of an LLM, characterized by their highly
    non-Gaussian output distributions, their role in mapping similar inputs to dissimilar
    outputs, and their significant impact on model accuracy. To study these phenomena,
    we propose a new experimental framework for disentangling polysemantic neurons.
    Our framework separates each layer''s inputs to create a mixture of experts where
    each neuron''s output is computed by a mixture of neurons of lower Wasserstein
    distance, each better at maintaining accuracy when sparsified without retraining.
    We provide strong evidence that this is because the mixture of sparse experts
    is effectively disentangling the input-output relationship of individual neurons,
    in particular the difficult Wasserstein neurons.'
acknowledgement: "The authors would like to extend their gratitude to Lori Leu for
  her insightful comments on the\r\napplication of the Wasserstein distance metric.
  We also wish to thank Elias Frantar for his help in\r\nworking with the SparseGPT
  implementation and his advice for the project. Additionally, we would like to thank
  Tony Tong Wang and Thomas Athey for their valuable feedback and constructive discussions.\r\nThis
  work was supported by an NIH Brains CONNECTS U01 grant and AMD’s AI & HPC Fund."
article_processing_charge: No
arxiv: 1
author:
- first_name: Shashata
  full_name: Sawmya, Shashata
  last_name: Sawmya
- first_name: Linghao
  full_name: Kong, Linghao
  last_name: Kong
- first_name: Ilia
  full_name: Markov, Ilia
  id: D0CF4148-C985-11E9-8066-0BDEE5697425
  last_name: Markov
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Nir
  full_name: Shavit, Nir
  last_name: Shavit
citation:
  ama: 'Sawmya S, Kong L, Markov I, Alistarh D-A, Shavit N. Wasserstein distances,
    neuronal entanglement, and sparsity. In: <i>13th International Conference on Learning
    Representations</i>. ICLR; 2025:26244-26274.'
  apa: 'Sawmya, S., Kong, L., Markov, I., Alistarh, D.-A., &#38; Shavit, N. (2025).
    Wasserstein distances, neuronal entanglement, and sparsity. In <i>13th International
    Conference on Learning Representations</i> (pp. 26244–26274). Singapore, Singapore:
    ICLR.'
  chicago: Sawmya, Shashata, Linghao Kong, Ilia Markov, Dan-Adrian Alistarh, and Nir
    Shavit. “Wasserstein Distances, Neuronal Entanglement, and Sparsity.” In <i>13th
    International Conference on Learning Representations</i>, 26244–74. ICLR, 2025.
  ieee: S. Sawmya, L. Kong, I. Markov, D.-A. Alistarh, and N. Shavit, “Wasserstein
    distances, neuronal entanglement, and sparsity,” in <i>13th International Conference
    on Learning Representations</i>, Singapore, Singapore, 2025, pp. 26244–26274.
  ista: 'Sawmya S, Kong L, Markov I, Alistarh D-A, Shavit N. 2025. Wasserstein distances,
    neuronal entanglement, and sparsity. 13th International Conference on Learning
    Representations. ICLR: International Conference on Learning Representations, 26244–26274.'
  mla: Sawmya, Shashata, et al. “Wasserstein Distances, Neuronal Entanglement, and
    Sparsity.” <i>13th International Conference on Learning Representations</i>, ICLR,
    2025, pp. 26244–74.
  short: S. Sawmya, L. Kong, I. Markov, D.-A. Alistarh, N. Shavit, in:, 13th International
    Conference on Learning Representations, ICLR, 2025, pp. 26244–26274.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
corr_author: '1'
date_created: 2025-07-20T22:02:03Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:16:43Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2405.15756'
file:
- access_level: open_access
  checksum: 39a8fa7dbdd7029859e156f53f20f6bc
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:14:09Z
  date_updated: 2025-08-04T08:14:09Z
  file_id: '20110'
  file_name: 2025_ICLR_Sawmya.pdf
  file_size: 5447177
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:14:09Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 26244-26274
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/Shavit-Lab/Sparse-Expansion
scopus_import: '1'
status: public
title: Wasserstein distances, neuronal entanglement, and sparsity
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '20038'
abstract:
- lang: eng
  text: Pruning eliminates unnecessary parameters in neural networks; it offers a
    promising solution to the growing computational demands of large language models
    (LLMs). While many focus on post-training pruning, sparse pre-training--which
    combines pruning and pre-training into a single phase--provides a simpler alternative.
    In this work, we present the first systematic exploration of optimal sparse pre-training
    configurations for LLMs through an examination of 80 unique pruning schedules
    across different sparsity levels and training durations. We find that initiating
    pruning at 25% of total training compute and concluding at 75% achieves near-optimal
    final evaluation loss. These findings provide valuable insights for efficient
    and effective sparse pre-training of LLMs. Furthermore, we propose a new scaling
    law that modifies the Chinchilla scaling law to use the average parameter count
    over pre-training. Through empirical and theoretical validation, we demonstrate
    that this modified scaling law accurately models evaluation loss for both sparsely
    and densely pre-trained LLMs, unifying scaling laws across pre-training paradigms.
    Our findings indicate that while sparse pre-training achieves the same final model
    quality as dense pre-training for equivalent compute budgets, it provides substantial
    benefits through reduced model size, enabling significant potential computational
    savings during inference.
acknowledgement: "We are deeply grateful to Elias Frantar, Naveen Kumar, Sanjiv Kumar,
  Daniel\r\nM. Roy, and Clemens Schaefer for their valuable feedback and thoughtful
  review of this paper.\r\nWe also acknowledge the critical support provided by the
  Google CoreML Performance Team, and Google Research during this project. We further
  recognize the extended team at Google DeepMind, who enabled and supported this research
  direction.\r\nThis work was in part supported by the Sloan Foundation, the MIT-IBM
  Watson AI Lab, Apple, and SRC JUMP 2.0 (CoCoSys)."
article_processing_charge: No
arxiv: 1
author:
- first_name: Tian
  full_name: Jin, Tian
  last_name: Jin
- first_name: Ahmed Imtiaz
  full_name: Humayun, Ahmed Imtiaz
  last_name: Humayun
- first_name: Utku
  full_name: Evci, Utku
  last_name: Evci
- first_name: Suvinay
  full_name: Subramanian, Suvinay
  last_name: Subramanian
- first_name: Amir
  full_name: Yazdanbakhsh, Amir
  last_name: Yazdanbakhsh
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Gintare Karolina
  full_name: Dziugaite, Gintare Karolina
  last_name: Dziugaite
citation:
  ama: 'Jin T, Humayun AI, Evci U, et al. The journey matters: Average parameter count
    over pre-training unifies sparse and dense scaling laws. In: <i>13th International
    Conference on Learning Representations</i>. ICLR; 2025:85165-85181.'
  apa: 'Jin, T., Humayun, A. I., Evci, U., Subramanian, S., Yazdanbakhsh, A., Alistarh,
    D.-A., &#38; Dziugaite, G. K. (2025). The journey matters: Average parameter count
    over pre-training unifies sparse and dense scaling laws. In <i>13th International
    Conference on Learning Representations</i> (pp. 85165–85181). Singapore, Singapore:
    ICLR.'
  chicago: 'Jin, Tian, Ahmed Imtiaz Humayun, Utku Evci, Suvinay Subramanian, Amir
    Yazdanbakhsh, Dan-Adrian Alistarh, and Gintare Karolina Dziugaite. “The Journey
    Matters: Average Parameter Count over Pre-Training Unifies Sparse and Dense Scaling
    Laws.” In <i>13th International Conference on Learning Representations</i>, 85165–81.
    ICLR, 2025.'
  ieee: 'T. Jin <i>et al.</i>, “The journey matters: Average parameter count over
    pre-training unifies sparse and dense scaling laws,” in <i>13th International
    Conference on Learning Representations</i>, Singapore, Singapore, 2025, pp. 85165–85181.'
  ista: 'Jin T, Humayun AI, Evci U, Subramanian S, Yazdanbakhsh A, Alistarh D-A, Dziugaite
    GK. 2025. The journey matters: Average parameter count over pre-training unifies
    sparse and dense scaling laws. 13th International Conference on Learning Representations.
    ICLR: International Conference on Learning Representations, 85165–85181.'
  mla: 'Jin, Tian, et al. “The Journey Matters: Average Parameter Count over Pre-Training
    Unifies Sparse and Dense Scaling Laws.” <i>13th International Conference on Learning
    Representations</i>, ICLR, 2025, pp. 85165–81.'
  short: T. Jin, A.I. Humayun, U. Evci, S. Subramanian, A. Yazdanbakhsh, D.-A. Alistarh,
    G.K. Dziugaite, in:, 13th International Conference on Learning Representations,
    ICLR, 2025, pp. 85165–85181.
conference:
  end_date: 2025-04-28
  location: Singapore, Singapore
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2025-04-24
date_created: 2025-07-20T22:02:03Z
date_published: 2025-04-01T00:00:00Z
date_updated: 2025-08-04T08:24:59Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
external_id:
  arxiv:
  - '2501.12486 '
file:
- access_level: open_access
  checksum: dbc27120e9aba67dffbd9e5d513a6803
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-04T08:23:47Z
  date_updated: 2025-08-04T08:23:47Z
  file_id: '20111'
  file_name: 2025_ICLR_Jin.pdf
  file_size: 704989
  relation: main_file
  success: 1
file_date_updated: 2025-08-04T08:23:47Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 85165-85181
publication: 13th International Conference on Learning Representations
publication_identifier:
  isbn:
  - '9798331320850'
publication_status: published
publisher: ICLR
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The journey matters: Average parameter count over pre-training unifies sparse
  and dense scaling laws'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20040'
abstract:
- lang: eng
  text: 'Contractive coupling rates have been recently introduced by Conforti as a
    tool to establish convex Sobolev inequalities (including modified log-Sobolev
    and Poincaré inequality) for some classes of Markov chains. In this work, for
    most of the examples discussed by Conforti, we use contractive coupling rates
    to prove stronger inequalities, in the form of curvature lower bounds (in entropic
    and discrete Bakry–Émery sense) and geodesic convexity of some entropic functionals.
    In addition, we recall and give straightforward generalizations of some notions
    of coarse Ricci curvature, and we discuss some of their properties and relations
    with the concepts of couplings and coupling rates: as an application, we show
    exponential contraction of the p-Wasserstein distance for the heat flow in the
    aforementioned examples.'
acknowledgement: "The author warmly thanks Jan Maas for suggesting the project and
  for his guidance, and Melchior Wirth and Haonan Zhang for useful discussions. The
  author is also grateful to an anonymous reviewer for carefully reading the manuscript
  and providing many valuable suggestions. The author gratefully acknowledges support
  by the European Research Council (ERC) under the European Union’s Horizon 2020 research
  and innovation programme\r\n(grant agreement No. 716117) and by the Austrian Science
  Fund (FWF), Project SFB F65."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Francesco
  full_name: Pedrotti, Francesco
  id: d3ac8ac6-dc8d-11ea-abe3-e2a9628c4c3c
  last_name: Pedrotti
citation:
  ama: Pedrotti F. Contractive coupling rates and curvature lower bounds for Markov
    chains. <i>The Annals of Applied Probability</i>. 2025;35(1):196-250. doi:<a href="https://doi.org/10.1214/24-aap2113">10.1214/24-aap2113</a>
  apa: Pedrotti, F. (2025). Contractive coupling rates and curvature lower bounds
    for Markov chains. <i>The Annals of Applied Probability</i>. Institute of Mathematical
    Statistics. <a href="https://doi.org/10.1214/24-aap2113">https://doi.org/10.1214/24-aap2113</a>
  chicago: Pedrotti, Francesco. “Contractive Coupling Rates and Curvature Lower Bounds
    for Markov Chains.” <i>The Annals of Applied Probability</i>. Institute of Mathematical
    Statistics, 2025. <a href="https://doi.org/10.1214/24-aap2113">https://doi.org/10.1214/24-aap2113</a>.
  ieee: F. Pedrotti, “Contractive coupling rates and curvature lower bounds for Markov
    chains,” <i>The Annals of Applied Probability</i>, vol. 35, no. 1. Institute of
    Mathematical Statistics, pp. 196–250, 2025.
  ista: Pedrotti F. 2025. Contractive coupling rates and curvature lower bounds for
    Markov chains. The Annals of Applied Probability. 35(1), 196–250.
  mla: Pedrotti, Francesco. “Contractive Coupling Rates and Curvature Lower Bounds
    for Markov Chains.” <i>The Annals of Applied Probability</i>, vol. 35, no. 1,
    Institute of Mathematical Statistics, 2025, pp. 196–250, doi:<a href="https://doi.org/10.1214/24-aap2113">10.1214/24-aap2113</a>.
  short: F. Pedrotti, The Annals of Applied Probability 35 (2025) 196–250.
corr_author: '1'
date_created: 2025-07-21T07:49:15Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2025-11-05T13:50:07Z
day: '01'
department:
- _id: JaMa
doi: 10.1214/24-aap2113
ec_funded: 1
external_id:
  arxiv:
  - '2308.00516'
  isi:
  - '001434322900006'
intvolume: '        35'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2308.00516
month: '02'
oa: 1
oa_version: Preprint
page: 196 - 250
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
publication: The Annals of Applied Probability
publication_identifier:
  issn:
  - 1050-5164
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
related_material:
  record:
  - id: '17351'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Contractive coupling rates and curvature lower bounds for Markov chains
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '20043'
abstract:
- lang: eng
  text: We establish an isomorphism of complex K-theory of the moduli space  M  of
    “SL n​ ”-Higgs bundles of degree d and rank n (in the sense of Hausel–Thaddeus)
    and twisted complex K-theory of the orbifold  M  of PGL n​ -Higgs bundles of degree
    e, where (n,d)=(n,e)=1. Along the way, we prove the vanishing of torsion for H
    ∗ ( M ) and certain twisted complex K-theory groups of  M . We also extend Arinkin’s
    autoduality of compactified Jacobian to a derived equivalence between SL n​ -
    and PGL n​ -Hitchin systems over the elliptic locus. In the appendix, we develop
    a formalism of G-sheaves of spectra, generalising equivariant homotopy theory
    to a relative setting.
acknowledgement: "It is a pleasure to thank Tom Baird for sharing his insights about
  vanishing of torsion for H.M{1\r\n2/. Furthermore, we would like to thank him for
  bringing [25] to our attention. We also thank Alexander Kupers for enlightening
  conversations about the Atiyah–Hirzebruch spectral sequence and for pointing out
  a reference. We are grateful to Victoria Hoskins and Simon Pepin-Lehalleur for sharing
  a preprint of their recent paper on a motivic version of topological mirror symmetry
  and for useful remarks on Section 6. Anne Larsen pointed out that our previous proof
  Lemma 4.5 was incomplete, we thank her for bringing this to our attention. We are
  grateful to the anonymous referee for many valuable comments that have improved
  the paper tremendously. The report we received was one of the most detailed referee
  report either of us has ever seen. We thank them for their hard work and the resulting
  contribution to this paper. Michael Groechenig was supported by an NSERC discovery
  grant and an Alfred P. Sloan\r\nfellowship. Shiyu Shen has received funding from
  the European Union’s Horizon 2020 research\r\nand innovation program under the Marie
  Skłodowska-Curie grant agreement No. 101034413."
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Groechenig, Michael
  last_name: Groechenig
- first_name: Shiyu
  full_name: Shen, Shiyu
  id: 544cccd3-9005-11ec-87bc-94aef1c5b814
  last_name: Shen
  orcid: 0000-0002-4444-8718
citation:
  ama: Groechenig M, Shen S. Complex K-theory of moduli spaces of Higgs bundles. <i>Journal
    of the European Mathematical Society</i>. 2025. doi:<a href="https://doi.org/10.4171/jems/1601">10.4171/jems/1601</a>
  apa: Groechenig, M., &#38; Shen, S. (2025). Complex K-theory of moduli spaces of
    Higgs bundles. <i>Journal of the European Mathematical Society</i>. EMS Press.
    <a href="https://doi.org/10.4171/jems/1601">https://doi.org/10.4171/jems/1601</a>
  chicago: Groechenig, Michael, and Shiyu Shen. “Complex K-Theory of Moduli Spaces
    of Higgs Bundles.” <i>Journal of the European Mathematical Society</i>. EMS Press,
    2025. <a href="https://doi.org/10.4171/jems/1601">https://doi.org/10.4171/jems/1601</a>.
  ieee: M. Groechenig and S. Shen, “Complex K-theory of moduli spaces of Higgs bundles,”
    <i>Journal of the European Mathematical Society</i>. EMS Press, 2025.
  ista: Groechenig M, Shen S. 2025. Complex K-theory of moduli spaces of Higgs bundles.
    Journal of the European Mathematical Society.
  mla: Groechenig, Michael, and Shiyu Shen. “Complex K-Theory of Moduli Spaces of
    Higgs Bundles.” <i>Journal of the European Mathematical Society</i>, EMS Press,
    2025, doi:<a href="https://doi.org/10.4171/jems/1601">10.4171/jems/1601</a>.
  short: M. Groechenig, S. Shen, Journal of the European Mathematical Society (2025).
corr_author: '1'
date_created: 2025-07-21T07:54:50Z
date_published: 2025-03-20T00:00:00Z
date_updated: 2026-02-19T09:24:54Z
day: '20'
department:
- _id: TaHa
doi: 10.4171/jems/1601
ec_funded: 1
external_id:
  arxiv:
  - '2212.10695'
  isi:
  - '001608254800001'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4171/JEMS/1601
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Journal of the European Mathematical Society
publication_identifier:
  eissn:
  - 1435-9863
  issn:
  - 1435-9855
publication_status: epub_ahead
publisher: EMS Press
quality_controlled: '1'
status: public
title: Complex K-theory of moduli spaces of Higgs bundles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20044'
abstract:
- lang: eng
  text: Genetic trade-offs—which occur when variants that are beneficial in some contexts
    of natural selection are harmful in others—can influence a wide range of evolutionary
    phenomena, from the maintenance of genetic variation to the evolution of aging
    and sex differences. An extensive body of evolutionary theory has focused on the
    consequences of such trade-offs, and recent analyses of Fisher’s geometric model
    have further quantified the expected proportion of new mutations that exhibit
    trade-offs. However, the theory remains silent regarding the prevalence of trade-offs
    among the variants that contribute to adaptation. Here, we extend Fisher’s geometric
    model to predict the prevalence of trade-offs among the adaptive mutations that
    become established or fixed in a population. We consider trade-offs between sexes,
    habitats, fitness components, and temporally fluctuating environments. In all
    4 scenarios, trade-off alleles are consistently under-represented among established
    relative to new beneficial mutations—an effect that arises from the greater susceptibility
    of trade-off alleles to genetic drift. Adaptation during a population size decline
    exacerbates this deficit of trade-offs among established mutations, whereas population
    expansions dampen it. Consequently, threatened populations should primarily adapt
    using unconditionally beneficial alleles, while invasive populations are more
    prone to adaptation using variants that exhibit trade-offs.
acknowledgement: 'Support for this research came from the European Society of Evolutionary
  Biology (ESEB) through a “Special Topics Network” grant. Further financial support
  came from the European Research Council (ERC-2023-STG916 #101117517, to C.O.), the
  Swedish Research Council (#2022-03603, to C.O.; #2020‑03123, to E.I.S.), the Research
  Council of Norway (Norges forskningsråd #302619, to D.G.), the Alexander von Humboldt
  Foundation and the GenEvo graduate school (to H.K.), the Foundation for Zoological
  Research and the Birgitta Sintring Foundation (#S2024-0007, to M.K.Z.), a postdoctoral
  fellowship from the Consejo Nacional de Humanidades, Ciencias y Tecnología (to A.N.B.),
  and a H2020 Marie Skłodowska-Curie COFUND Action fellowship (#101034413, to F.R.).
  We wish to express our deepest gratitude to Lotte de Vries for extensive discussion
  of the project, rederiving some of our results, and providing comments on an earlier
  version of the manuscript, and to the European Society of Evolutionary Biology (ESEB)
  for a “Special Topics Network” grant that supported workshops that initiated this
  collaboration and facilitated many new ideas and friendships. We also thank two
  anonymous reviewers for their thoughtful comments and suggestions that helped us
  to substantially improve upon the original version of the article.'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Tim
  full_name: Connallon, Tim
  last_name: Connallon
- first_name: Peter
  full_name: Czuppon, Peter
  last_name: Czuppon
- first_name: Colin
  full_name: Olito, Colin
  last_name: Olito
- first_name: Debora
  full_name: Goedert, Debora
  last_name: Goedert
- first_name: Hanna
  full_name: Kokko, Hanna
  last_name: Kokko
- first_name: Angela
  full_name: Nava-Bolaños, Angela
  last_name: Nava-Bolaños
- first_name: Sofie
  full_name: Nilén, Sofie
  last_name: Nilén
- first_name: Erik I
  full_name: Svensson, Erik I
  last_name: Svensson
- first_name: Martyna
  full_name: Zwoinska, Martyna
  last_name: Zwoinska
- first_name: Ludovic
  full_name: Dutoit, Ludovic
  last_name: Dutoit
- first_name: Filip
  full_name: Ruzicka, Filip
  id: 347955dd-57b0-11ee-9095-c28bdd368f4b
  last_name: Ruzicka
citation:
  ama: Connallon T, Czuppon P, Olito C, et al. Predicting the prevalence of genetic
    trade-offs among adaptive substitutions. <i>Evolution</i>. 2025;79(7):1243-1255.
    doi:<a href="https://doi.org/10.1093/evolut/qpaf061">10.1093/evolut/qpaf061</a>
  apa: Connallon, T., Czuppon, P., Olito, C., Goedert, D., Kokko, H., Nava-Bolaños,
    A., … Ruzicka, F. (2025). Predicting the prevalence of genetic trade-offs among
    adaptive substitutions. <i>Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/evolut/qpaf061">https://doi.org/10.1093/evolut/qpaf061</a>
  chicago: Connallon, Tim, Peter Czuppon, Colin Olito, Debora Goedert, Hanna Kokko,
    Angela Nava-Bolaños, Sofie Nilén, et al. “Predicting the Prevalence of Genetic
    Trade-Offs among Adaptive Substitutions.” <i>Evolution</i>. Oxford University
    Press, 2025. <a href="https://doi.org/10.1093/evolut/qpaf061">https://doi.org/10.1093/evolut/qpaf061</a>.
  ieee: T. Connallon <i>et al.</i>, “Predicting the prevalence of genetic trade-offs
    among adaptive substitutions,” <i>Evolution</i>, vol. 79, no. 7. Oxford University
    Press, pp. 1243–1255, 2025.
  ista: Connallon T, Czuppon P, Olito C, Goedert D, Kokko H, Nava-Bolaños A, Nilén
    S, Svensson EI, Zwoinska M, Dutoit L, Ruzicka F. 2025. Predicting the prevalence
    of genetic trade-offs among adaptive substitutions. Evolution. 79(7), 1243–1255.
  mla: Connallon, Tim, et al. “Predicting the Prevalence of Genetic Trade-Offs among
    Adaptive Substitutions.” <i>Evolution</i>, vol. 79, no. 7, Oxford University Press,
    2025, pp. 1243–55, doi:<a href="https://doi.org/10.1093/evolut/qpaf061">10.1093/evolut/qpaf061</a>.
  short: T. Connallon, P. Czuppon, C. Olito, D. Goedert, H. Kokko, A. Nava-Bolaños,
    S. Nilén, E.I. Svensson, M. Zwoinska, L. Dutoit, F. Ruzicka, Evolution 79 (2025)
    1243–1255.
date_created: 2025-07-21T07:57:28Z
date_published: 2025-07-01T00:00:00Z
date_updated: 2025-09-30T14:06:38Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/evolut/qpaf061
ec_funded: 1
external_id:
  isi:
  - '001477180800001'
file:
- access_level: open_access
  checksum: 68c4c996d0e8c9ee3d4fb61bca75b31a
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-22T10:04:57Z
  date_updated: 2025-07-22T10:04:57Z
  file_id: '20068'
  file_name: 2025_Evolution_Connallon.pdf
  file_size: 8150623
  relation: main_file
  success: 1
file_date_updated: 2025-07-22T10:04:57Z
has_accepted_license: '1'
intvolume: '        79'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1243-1255
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Evolution
publication_identifier:
  eissn:
  - 1558-5646
  issn:
  - 0014-3820
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
status: public
title: Predicting the prevalence of genetic trade-offs among adaptive substitutions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 79
year: '2025'
...
