[{"publication":"Mathematical Models and Methods in Applied Sciences","article_type":"original","publication_status":"epub_ahead","abstract":[{"lang":"eng","text":"Both Newtonian and non-Newtonian fluids may exhibit complex slip behaviour at the boundary. We examine a broad class of slip boundary conditions that generalises the commonly used Navier slip, perfect slip, stick-slip and Tresca friction boundary conditions. In particular, set-valued, nonmonotone, noncoercive and dynamic relations may occur. For a unifying framework of such relations, we present a fully discrete numerical scheme for the time-dependent Navier–Stokes equations subject to impermeability and general slip-type boundary conditions on polyhedral domains. Based on compactness arguments, we prove convergence of subsequences, finally ensuring the existence of a weak solution. The numerical scheme uses a general inf-sup stable pair of finite element spaces for the velocity and pressure, a regularisation approach for the implicit slip boundary condition and, most importantly, a general Nitsche method to impose the impermeability and a backward Euler time stepping. One of the key tools in the convergence proof is an inhomogeneous Korn inequality that includes a normal trace term."}],"type":"journal_article","date_created":"2026-08-16T22:01:44Z","year":"2026","mathsc":["65N30","76D07","76M10"],"title":"A Nitsche method for incompressible fluids with general dynamic boundary conditions","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"World Scientific Publishing","publication_identifier":{"issn":["0218-2025"],"eissn":["1793-6314"]},"citation":{"chicago":"Gazca-Orozco, Pablo Alexei, Franz Gmeineder, Erika Maringová, and Tabea Tscherpel. “A Nitsche Method for Incompressible Fluids with General Dynamic Boundary Conditions.” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026. <a href=\"https://doi.org/10.1142/S0218202526500508\">https://doi.org/10.1142/S0218202526500508</a>.","apa":"Gazca-Orozco, P. A., Gmeineder, F., Maringová, E., &#38; Tscherpel, T. (2026). A Nitsche method for incompressible fluids with general dynamic boundary conditions. <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0218202526500508\">https://doi.org/10.1142/S0218202526500508</a>","ieee":"P. A. Gazca-Orozco, F. Gmeineder, E. Maringová, and T. Tscherpel, “A Nitsche method for incompressible fluids with general dynamic boundary conditions,” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026.","short":"P.A. Gazca-Orozco, F. Gmeineder, E. Maringová, T. Tscherpel, Mathematical Models and Methods in Applied Sciences (2026).","ista":"Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. 2026. A Nitsche method for incompressible fluids with general dynamic boundary conditions. Mathematical Models and Methods in Applied Sciences.","mla":"Gazca-Orozco, Pablo Alexei, et al. “A Nitsche Method for Incompressible Fluids with General Dynamic Boundary Conditions.” <i>Mathematical Models and Methods in Applied Sciences</i>, World Scientific Publishing, 2026, doi:<a href=\"https://doi.org/10.1142/S0218202526500508\">10.1142/S0218202526500508</a>.","ama":"Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. A Nitsche method for incompressible fluids with general dynamic boundary conditions. <i>Mathematical Models and Methods in Applied Sciences</i>. 2026. doi:<a href=\"https://doi.org/10.1142/S0218202526500508\">10.1142/S0218202526500508</a>"},"_id":"22718","date_updated":"2026-08-18T07:51:59Z","OA_type":"green","oa":1,"date_published":"2026-08-04T00:00:00Z","external_id":{"arxiv":["2502.09550"]},"status":"public","quality_controlled":"1","department":[{"_id":"JuFi"}],"oa_version":"Preprint","arxiv":1,"author":[{"last_name":"Gazca-Orozco","full_name":"Gazca-Orozco, Pablo Alexei","first_name":"Pablo Alexei"},{"first_name":"Franz","last_name":"Gmeineder","full_name":"Gmeineder, Franz"},{"last_name":"Maringová","full_name":"Maringová, Erika","first_name":"Erika","id":"dbabca31-66eb-11eb-963a-fb9c22c880b4"},{"first_name":"Tabea","full_name":"Tscherpel, Tabea","last_name":"Tscherpel"}],"doi":"10.1142/S0218202526500508","month":"08","day":"04","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2502.09550"}],"scopus_import":"1","language":[{"iso":"eng"}],"article_processing_charge":"No","OA_place":"repository"},{"date_created":"2026-08-18T11:34:03Z","type":"journal_article","ddc":["540"],"file":[{"content_type":"application/pdf","date_created":"2026-08-19T05:52:41Z","date_updated":"2026-08-19T05:52:41Z","creator":"dernst","file_id":"22736","checksum":"4d75c5a79d112c845c9eecba8838db38","file_name":"2026_ACSEnergyLetters_Liu.pdf","file_size":6806815,"success":1,"relation":"main_file","access_level":"open_access"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"abstract":[{"lang":"eng","text":"Silver selenide (Ag2Se) is a promising near-room-temperature thermoelectric material, but its narrow stoichiometric window and β–α phase transition complicate reproducible microstructure control. Here, we present a mismatch-assisted microstructure engineering strategy in which Ag2Se particles are treated with polyanionic ZnSe complexes and consolidated through the β–α transition to introduce ZnSe nanoprecipitates, Ag2Se/ZnSe interfaces, and local strain fields. The crystallographic mismatch between ZnSe and Ag2Se, together with the Zn2+/Ag+ size difference, amplifies phase-transition-induced deformation and promotes high-density dislocations with periodic strain modulations. This defect architecture suppresses grain coarsening, removes excess Ag, limits Ag-interstitial formation, and reduces lattice thermal conductivity through lattice softening and multiscale phonon scattering. Ag2Se–4%ZnSe nanocomposites achieve a peak zTmax of 1.13 at 369 K and a zTavg of 1.08 from 300 to 380 K, demonstrating mismatch-driven defect engineering through the β–α phase transition as a route for optimizing Ag2Se-based thermoelectrics."}],"article_type":"letter_note","publication_status":"published","publication":"ACS Energy Letters","volume":11,"date_updated":"2026-08-19T05:53:33Z","_id":"22734","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"NanoFab"},{"_id":"MassSpec"}],"citation":{"ista":"Liu Y, Kleinhanns T, Spadaro MC, Genç A, Horta S, Jakhar N, Costanzo T, Dutkiewicz E, Arbiol J, Hong M, Ibáñez M. 2026. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. ACS Energy Letters. 11(8), 5752–5762.","mla":"Liu, Yu, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>, vol. 11, no. 8, American Chemical Society, 2026, pp. 5752–62, doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>.","short":"Y. Liu, T. Kleinhanns, M.C. Spadaro, A. Genç, S. Horta, N. Jakhar, T. Costanzo, E. Dutkiewicz, J. Arbiol, M. Hong, M. Ibáñez, ACS Energy Letters 11 (2026) 5752–5762.","ieee":"Y. Liu <i>et al.</i>, “Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se,” <i>ACS Energy Letters</i>, vol. 11, no. 8. American Chemical Society, pp. 5752–5762, 2026.","apa":"Liu, Y., Kleinhanns, T., Spadaro, M. C., Genç, A., Horta, S., Jakhar, N., … Ibáñez, M. (2026). Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>","chicago":"Liu, Yu, Tobias Kleinhanns, Maria Chiara Spadaro, Aziz Genç, Sharona Horta, Navita Jakhar, Tommaso Costanzo, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">https://doi.org/10.1021/acsenergylett.6c01499</a>.","ama":"Liu Y, Kleinhanns T, Spadaro MC, et al. Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>. 2026;11(8):5752-5762. doi:<a href=\"https://doi.org/10.1021/acsenergylett.6c01499\">10.1021/acsenergylett.6c01499</a>"},"publication_identifier":{"eissn":["2380-8195"]},"publisher":"American Chemical Society","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Exploiting mismatch strain and the β–α phase transition for microstructural engineering in thermoelectric Ag2Se","year":"2026","intvolume":"        11","author":[{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","last_name":"Liu","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740","first_name":"Yu"},{"id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425","orcid":"0000-0003-1537-7436","last_name":"Kleinhanns","full_name":"Kleinhanns, Tobias","first_name":"Tobias"},{"last_name":"Spadaro","full_name":"Spadaro, Maria Chiara","first_name":"Maria Chiara"},{"first_name":"Aziz","full_name":"Genç, Aziz","last_name":"Genç"},{"last_name":"Horta","full_name":"Horta, Sharona","first_name":"Sharona","id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc"},{"id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","orcid":"0000-0001-7408-8197","full_name":"Navita, Navita","last_name":"Navita","first_name":"Navita"},{"orcid":"0000-0001-9732-3815","last_name":"Costanzo","full_name":"Costanzo, Tommaso","first_name":"Tommaso","id":"D93824F4-D9BA-11E9-BB12-F207E6697425"},{"id":"0601cc46-c082-11ec-9b07-bb29641d1de9","first_name":"Ewelina","full_name":"Dutkiewicz, Ewelina","last_name":"Dutkiewicz"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"first_name":"Min","full_name":"Hong, Min","last_name":"Hong"},{"first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria","last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87"}],"supplementarymaterial":"yes","corr_author":"1","acknowledgement":"Open access funding provided by Institute of Science and Technology Austria. M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation. The Scientific Service Units (SSU) of ISTA supported this work through resources provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF), the Nanofabrication Facility (NNF), and the Mass Spectrometry Facility. Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (grant no. 22209034) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). M.H. acknowledges funding from Australian Research Council (FT230100316), and the high-performance computing resources provided by National Computational Infrastructure (it39) and Pawsey Supercomputing Centre (pawsey1075). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by the “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (grant no.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Authors acknowledge the use of instrumentation as well as the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is founding member of e-DREAM. (91)","page":"5752-5762","oa_version":"Published Version","department":[{"_id":"MassSpec"},{"_id":"MaIb"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"quality_controlled":"1","status":"public","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"date_published":"2026-08-14T00:00:00Z","OA_type":"hybrid","oa":1,"has_accepted_license":"1","issue":"8","OA_place":"publisher","article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"researchdata_availability":"no","scopus_import":"1","day":"14","PlanS_conform":"1","file_date_updated":"2026-08-19T05:52:41Z","month":"08","das_tickbox":"0","doi":"10.1021/acsenergylett.6c01499"},{"OA_type":"hybrid","oa":1,"date_published":"2026-08-01T00:00:00Z","oa_version":"Published Version","department":[{"_id":"LifeSc"}],"status":"public","quality_controlled":"1","page":"1247-1253","author":[{"full_name":"Hörmann, Anja F.","last_name":"Hörmann","first_name":"Anja F."},{"first_name":"Daniel","orcid":"0000-0001-7597-043X","last_name":"Balazs","full_name":"Balazs, Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E"},{"first_name":"Ingo","full_name":"Breßler, Ingo","last_name":"Breßler"},{"first_name":"Sumea","last_name":"Klokic","full_name":"Klokic, Sumea"},{"first_name":"Melika","last_name":"Moradi","full_name":"Moradi, Melika"},{"last_name":"Solano","full_name":"Solano, Eduardo","first_name":"Eduardo"},{"first_name":"Annika","full_name":"Stellhorn, Annika","last_name":"Stellhorn"},{"first_name":"Brian R.","last_name":"Pauw","full_name":"Pauw, Brian R."}],"acknowledgement":"The authors thank all respondents for their participation in the\r\nquestionnaire. We plan to make further use of the wealth of\r\nthe dataset going forward. We thank Xenocs for sharing\r\napproximate data on GISAXS equipment sales and Adrian\r\nRennie for helpful discussions. Open access funding enabled\r\nand organized by Projekt DEAL.","supplementarymaterial":"no","intvolume":"        59","dataavailabilitystatement":"The response data are available at https://doi.org/10.5281/\r\nzenodo.18712813. The literate programming source of this\r\nwork is available at https://doi.org/10.5281/zenodo.18713631.","doi":"10.1107/S1600576726005741","das_tickbox":"1","month":"08","PlanS_conform":"1","file_date_updated":"2026-08-20T05:51:36Z","day":"01","article_processing_charge":"Yes (via OA deal)","language":[{"iso":"eng"}],"researchdata_availability":"yes","scopus_import":"1","issue":"4","OA_place":"publisher","has_accepted_license":"1","volume":59,"keyword":["grazing incidence","reference methods","calibration","standardization","community"],"publication":"Journal of Applied Crystallography","publication_status":"published","article_type":"original","abstract":[{"lang":"eng","text":"Grazing-incidence small-angle scattering (GISAS) is a relatively young technique with important applications in thin-film technology and untapped potential when it comes to 2D analysis on an absolute intensity scale. Approaching standardization and reference methods early is foundational for reproducibility and comparability across laboratories and reduction of systematic error sources. It underpins trust in data obtained and accelerates innovation by ensuring that scientists work from a common methodological baseline. Accordingly, obtaining reproducible results from different GISAS instruments requires an agreement on how measurements are performed, instruments calibrated and terms defined. To pave the way for standardization and reference methods, we surveyed GISAS practitioners on what comes before an experiment: hardware, software, sample alignment and instrument calibration. Twenty-two questions were designed to elucidate the state of the art, which can be used for the development of reference methods. Our data on 27 instruments provide the basis for standardization. With very few exceptions, we found laboratories prepared to implement future reference methods, but no consensus emerges naturally for sample alignment and instrument calibration. We, that is the GISAS community, are thus in a position to embark on the journey of standardization."}],"ddc":["540"],"file":[{"file_name":"2026_JourAppliedCrystallography_Hoermann.pdf","checksum":"8dbad0ab078338021e2cfe722211df7b","file_id":"22739","access_level":"open_access","success":1,"relation":"main_file","file_size":6692218,"date_created":"2026-08-20T05:51:36Z","date_updated":"2026-08-20T05:51:36Z","content_type":"application/pdf","creator":"dernst"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"type":"journal_article","date_created":"2026-08-16T22:01:43Z","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"International Union of Crystallography","title":"Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration","publication_identifier":{"issn":["0021-8898"],"eissn":["1600-5767"]},"citation":{"ieee":"A. F. Hörmann <i>et al.</i>, “Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration,” <i>Journal of Applied Crystallography</i>, vol. 59, no. 4. International Union of Crystallography, pp. 1247–1253, 2026.","short":"A.F. Hörmann, D. Balazs, I. Breßler, S. Klokic, M. Moradi, E. Solano, A. Stellhorn, B.R. Pauw, Journal of Applied Crystallography 59 (2026) 1247–1253.","ista":"Hörmann AF, Balazs D, Breßler I, Klokic S, Moradi M, Solano E, Stellhorn A, Pauw BR. 2026. Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. Journal of Applied Crystallography. 59(4), 1247–1253.","mla":"Hörmann, Anja F., et al. “Grazing-Incidence Scattering Surveyed: Towards Reference Methods for Alignment and Calibration.” <i>Journal of Applied Crystallography</i>, vol. 59, no. 4, International Union of Crystallography, 2026, pp. 1247–53, doi:<a href=\"https://doi.org/10.1107/S1600576726005741\">10.1107/S1600576726005741</a>.","chicago":"Hörmann, Anja F., Daniel Balazs, Ingo Breßler, Sumea Klokic, Melika Moradi, Eduardo Solano, Annika Stellhorn, and Brian R. Pauw. “Grazing-Incidence Scattering Surveyed: Towards Reference Methods for Alignment and Calibration.” <i>Journal of Applied Crystallography</i>. International Union of Crystallography, 2026. <a href=\"https://doi.org/10.1107/S1600576726005741\">https://doi.org/10.1107/S1600576726005741</a>.","apa":"Hörmann, A. F., Balazs, D., Breßler, I., Klokic, S., Moradi, M., Solano, E., … Pauw, B. R. (2026). Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. <i>Journal of Applied Crystallography</i>. International Union of Crystallography. <a href=\"https://doi.org/10.1107/S1600576726005741\">https://doi.org/10.1107/S1600576726005741</a>","ama":"Hörmann AF, Balazs D, Breßler I, et al. Grazing-incidence scattering surveyed: Towards reference methods for alignment and calibration. <i>Journal of Applied Crystallography</i>. 2026;59(4):1247-1253. doi:<a href=\"https://doi.org/10.1107/S1600576726005741\">10.1107/S1600576726005741</a>"},"_id":"22715","date_updated":"2026-08-20T06:14:07Z"},{"OA_place":"publisher","issue":"3","has_accepted_license":"1","day":"06","researchdata_availability":"no","scopus_import":"1","language":[{"iso":"eng"}],"article_processing_charge":"Yes","month":"07","file_date_updated":"2026-08-20T06:19:51Z","PlanS_conform":"1","doi":"10.1145/3816252","das_tickbox":"0","intvolume":"        22","arxiv":1,"acknowledgement":"M. Henzinger: This project has received funding from the European Research Council (ERC) under the European Union’s\r\nHorizon 2020 research and innovation programme (MoDynStruct, No. 101019564)   and the Austrian Science Fund\r\n(FWF) grant DOI 10.55776/Z422, grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775 with additional funding from the\r\nnetidee SCIENCE Stiftung, 2020–2024. Views and opinions expressed are those of the author(s) only and do not necessarily\r\nreflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor\r\nthe granting authority can be held responsible for them","corr_author":"1","supplementarymaterial":"yes","author":[{"first_name":"Gramoz","full_name":"Goranci, Gramoz","last_name":"Goranci"},{"id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H","last_name":"Henzinger","full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530"},{"first_name":"Harald","last_name":"Räcke","full_name":"Räcke, Harald"},{"last_name":"Sricharan","full_name":"Sricharan, A. R.","first_name":"A. R."}],"quality_controlled":"1","status":"public","department":[{"_id":"MoHe"}],"oa_version":"Published Version","OA_type":"gold","oa":1,"date_published":"2026-07-06T00:00:00Z","external_id":{"arxiv":["2502.09105"]},"project":[{"grant_number":"101019564","call_identifier":"H2020","name":"The design and evaluation of modern fully dynamic data structures","_id":"bd9ca328-d553-11ed-ba76-dc4f890cfe62"},{"name":"Efficient algorithms","_id":"34def286-11ca-11ed-8bc3-da5948e1613c","grant_number":"Z00422"},{"name":"Static and Dynamic Hierarchical Graph Decompositions","_id":"bda196b2-d553-11ed-ba76-8e8ee6c21103","grant_number":"I05982"},{"name":"Fast Algorithms for a Reactive Network Layer","_id":"bd9e3a2e-d553-11ed-ba76-8aa684ce17fe","grant_number":"P33775"}],"_id":"22716","date_updated":"2026-08-20T06:28:01Z","publication_identifier":{"eissn":["1549-6333"],"issn":["1549-6325"]},"citation":{"ieee":"G. Goranci, M. Henzinger, H. Räcke, and A. R. Sricharan, “Incremental approximate maximum flow via residual graph sparsification,” <i>ACM Transactions on Algorithms</i>, vol. 22, no. 3. ACM, 2026.","short":"G. Goranci, M. Henzinger, H. Räcke, A.R. Sricharan, ACM Transactions on Algorithms 22 (2026).","ista":"Goranci G, Henzinger M, Räcke H, Sricharan AR. 2026. Incremental approximate maximum flow via residual graph sparsification. ACM Transactions on Algorithms. 22(3), 31.","mla":"Goranci, Gramoz, et al. “Incremental Approximate Maximum Flow via Residual Graph Sparsification.” <i>ACM Transactions on Algorithms</i>, vol. 22, no. 3, 31, ACM, 2026, doi:<a href=\"https://doi.org/10.1145/3816252\">10.1145/3816252</a>.","chicago":"Goranci, Gramoz, Monika Henzinger, Harald Räcke, and A. R. Sricharan. “Incremental Approximate Maximum Flow via Residual Graph Sparsification.” <i>ACM Transactions on Algorithms</i>. ACM, 2026. <a href=\"https://doi.org/10.1145/3816252\">https://doi.org/10.1145/3816252</a>.","apa":"Goranci, G., Henzinger, M., Räcke, H., &#38; Sricharan, A. R. (2026). Incremental approximate maximum flow via residual graph sparsification. <i>ACM Transactions on Algorithms</i>. ACM. <a href=\"https://doi.org/10.1145/3816252\">https://doi.org/10.1145/3816252</a>","ama":"Goranci G, Henzinger M, Räcke H, Sricharan AR. Incremental approximate maximum flow via residual graph sparsification. <i>ACM Transactions on Algorithms</i>. 2026;22(3). doi:<a href=\"https://doi.org/10.1145/3816252\">10.1145/3816252</a>"},"ec_funded":1,"title":"Incremental approximate maximum flow via residual graph sparsification","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"ACM","year":"2026","type":"journal_article","date_created":"2026-08-16T22:01:43Z","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"related_material":{"record":[{"id":"21280","relation":"earlier_version","status":"public"}]},"ddc":["000"],"file":[{"success":1,"relation":"main_file","file_size":2272512,"access_level":"open_access","file_id":"22740","file_name":"2026_TransactionsAlgorithms_Goranci.pdf","checksum":"97969d26dab25c3a35be3ae4dd0fd9ee","creator":"dernst","content_type":"application/pdf","date_created":"2026-08-20T06:19:51Z","date_updated":"2026-08-20T06:19:51Z"}],"article_number":"31","publication_status":"published","article_type":"original","abstract":[{"lang":"eng","text":"We give an algorithm that, with high probability, maintains a (1-ε)-approximate s-t maximum flow in undirected, uncapacitated n-vertex graphs undergoing m edge insertions in Õ(m+ n F^*/ε) total update time, where F^{*} is the maximum flow on the final graph. This is the first algorithm to achieve polylogarithmic amortized update time for dense graphs (m = Ω(n²)), and more generally, for graphs where F^* = Õ(m/n). At the heart of our incremental algorithm is the residual graph sparsification technique of Karger and Levine [SICOMP '15], originally designed for computing exact maximum flows in the static setting. Our main contributions are (i) showing how to maintain such sparsifiers for approximate maximum flows in the incremental setting and (ii) generalizing the cut sparsification framework of Fung et al. [SICOMP '19] from undirected graphs to balanced directed graphs."}],"volume":22,"publication":"ACM Transactions on Algorithms"},{"supplementarymaterial":"yes","acknowledgement":"We thank M. caouyette for the plasmid construction for Pou3f1overexpression; d. Pinto-Benito for valuable assistance with shRnA validation in n2A cells andqPcR experiments; c. Varela-Martínez for help with the code for graphical analysis; allmembers from the nieto’s lab for comment on the manuscript, specially to F. Martín for theinsightful discussions; J. c. Oliveros and J. A. García from the computational service of the cnBfor help with the analysis of RnAseq dataset; c. O. Sorzano for help with statistical analysis; andA. Oña and the service of Advance Optical Microscopy of the cnB for technical advice.Funding: i.V.-M. holds a fellowship funded by MciciU (PRe-2018-083376) and 2023 eMBOscientific exchange grant 10214. the work was funded by grants to M.n. (Pid2020-112831GB- i00 and Pid2023-146322nB- i00 by Mcin/Aei/10.13039/501100011033 and by“eRdF A way of making europe”).","author":[{"id":"a69b5985-8829-11f0-8fc2-d0af58f64471","full_name":"Varela Martínez, Irene","last_name":"Varela Martínez","first_name":"Irene"},{"id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana","last_name":"Villalba Requena","full_name":"Villalba Requena, Ana","orcid":"0000-0002-5615-5277"},{"first_name":"Jorge","full_name":"García-Marqués, Jorge","last_name":"García-Marqués"},{"first_name":"Alfonso","last_name":"Aguilera","full_name":"Aguilera, Alfonso"},{"first_name":"Diogo S.","last_name":"Castro","full_name":"Castro, Diogo S."},{"first_name":"Simon","full_name":"Hippenmeyer, Simon","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Marta","last_name":"Nieto","full_name":"Nieto, Marta"}],"page":"eadw5487","intvolume":"        12","dataavailabilitystatement":"All data and code needed to evaluate and reproduce the results in the paper are present in the paper and/or the Supplementary Materials. Source data underlying all figures (including the clonal atlas) are provided in the Supplementary Materials. RnA-seq analysis code has been deposited in Zenodo (dOi: 10.5281/zenodo.14609057). this study did not generate new materials.","date_published":"2026-08-07T00:00:00Z","external_id":{"pmid":["42555737"]},"oa":1,"OA_type":"gold","quality_controlled":"1","status":"public","department":[{"_id":"SiHi"}],"oa_version":"Published Version","scopus_import":"1","researchdata_availability":"yes","language":[{"iso":"eng"}],"article_processing_charge":"Yes","day":"07","has_accepted_license":"1","OA_place":"publisher","issue":"32","das_tickbox":"1","doi":"10.1126/sciadv.adw5487","file_date_updated":"2026-08-20T05:39:32Z","PlanS_conform":"1","month":"08","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"file":[{"file_size":3056744,"success":1,"relation":"main_file","access_level":"open_access","file_id":"22738","checksum":"487c3703387080e8f3c4675d67763f0e","file_name":"2026_ScienceAdv_VarelaMartinez.pdf","creator":"dernst","content_type":"application/pdf","date_created":"2026-08-20T05:39:32Z","date_updated":"2026-08-20T05:39:32Z"}],"ddc":["570"],"date_created":"2026-08-16T22:01:43Z","type":"journal_article","publication":"Science Advances","volume":12,"abstract":[{"lang":"eng","text":"Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the cerebral cortex through incompletely understood processes. We combined Mosaic Analysis with Double Markers at embryonic stages (E)12.5 and E13.5 with early postnatal callosal tracing to dissect RGP lineage progression. We find that multipotent RGPs generate all extra-telencephalic (ET) and intra-telencephalic (IT) PNs via parallel sublineages that emerge simultaneously at neurogenesis onset. ET-PN production progresses exclusively via small, self-consuming lineages; IT-PN lineages feature RGPs generating large translaminar outputs. The early emergence of IT-PN–fated RGPs, coinciding with a switch to direct neurogenesis, contributes to the stereotyped population-level progression of the multipotent lineage. We also identify POU3F transcription factors as candidate regulators of IT-PN fate via noncanonical mitotic chromatin binding. The results support a model whereby IT- and ET-PNs arise from an early bifurcation and parallel specification within the multipotent RGP lineage."}],"publication_status":"published","article_type":"original","citation":{"short":"I. Varela Martínez, A. Villalba Requena, J. García-Marqués, A. Aguilera, D.S. Castro, S. Hippenmeyer, M. Nieto, Science Advances 12 (2026) eadw5487.","ieee":"I. Varela Martínez <i>et al.</i>, “Early fate diversification of radial glial progenitors during corticogenesis,” <i>Science Advances</i>, vol. 12, no. 32. AAAS, p. eadw5487, 2026.","ista":"Varela Martínez I, Villalba Requena A, García-Marqués J, Aguilera A, Castro DS, Hippenmeyer S, Nieto M. 2026. Early fate diversification of radial glial progenitors during corticogenesis. Science Advances. 12(32), eadw5487.","mla":"Varela Martínez, Irene, et al. “Early Fate Diversification of Radial Glial Progenitors during Corticogenesis.” <i>Science Advances</i>, vol. 12, no. 32, AAAS, 2026, p. eadw5487, doi:<a href=\"https://doi.org/10.1126/sciadv.adw5487\">10.1126/sciadv.adw5487</a>.","chicago":"Varela Martínez, Irene, Ana Villalba Requena, Jorge García-Marqués, Alfonso Aguilera, Diogo S. Castro, Simon Hippenmeyer, and Marta Nieto. “Early Fate Diversification of Radial Glial Progenitors during Corticogenesis.” <i>Science Advances</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/sciadv.adw5487\">https://doi.org/10.1126/sciadv.adw5487</a>.","apa":"Varela Martínez, I., Villalba Requena, A., García-Marqués, J., Aguilera, A., Castro, D. S., Hippenmeyer, S., &#38; Nieto, M. (2026). Early fate diversification of radial glial progenitors during corticogenesis. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.adw5487\">https://doi.org/10.1126/sciadv.adw5487</a>","ama":"Varela Martínez I, Villalba Requena A, García-Marqués J, et al. Early fate diversification of radial glial progenitors during corticogenesis. <i>Science Advances</i>. 2026;12(32):eadw5487. doi:<a href=\"https://doi.org/10.1126/sciadv.adw5487\">10.1126/sciadv.adw5487</a>"},"publication_identifier":{"eissn":["2375-2548"]},"date_updated":"2026-08-20T05:45:28Z","pmid":1,"_id":"22714","DOAJ_listed":"1","year":"2026","title":"Early fate diversification of radial glial progenitors during corticogenesis","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"AAAS"},{"intvolume":"       123","author":[{"full_name":"Piao, Chengji","last_name":"Piao","first_name":"Chengji"},{"full_name":"Dutkiewicz, Ewelina","last_name":"Dutkiewicz","first_name":"Ewelina","id":"0601cc46-c082-11ec-9b07-bb29641d1de9"},{"first_name":"Laxmikanth","full_name":"Kollipara, Laxmikanth","last_name":"Kollipara"},{"full_name":"Sickmann, Albert","last_name":"Sickmann","first_name":"Albert"},{"first_name":"Sheng","full_name":"Huang, Sheng","last_name":"Huang"},{"first_name":"Stephan J.","full_name":"Sigrist, Stephan J.","last_name":"Sigrist"}],"extern":"1","quality_controlled":"1","status":"public","oa_version":"Published Version","date_published":"2026-06-16T00:00:00Z","external_id":{"pmid":["42258713"]},"OA_type":"hybrid","oa":1,"has_accepted_license":"1","OA_place":"publisher","issue":"24","scopus_import":"1","language":[{"iso":"eng"}],"article_processing_charge":"Yes (in subscription journal)","day":"16","PlanS_conform":"1","file_date_updated":"2026-08-20T05:34:25Z","month":"06","doi":"10.1073/pnas.2524065123","date_created":"2026-08-18T10:46:33Z","type":"journal_article","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["570"],"file":[{"date_created":"2026-08-20T05:34:25Z","date_updated":"2026-08-20T05:34:25Z","content_type":"application/pdf","creator":"dernst","file_name":"2026_PNAS_Piao.pdf","checksum":"3727c5ad18c1e9c65672fbb01ac6ea04","file_id":"22737","access_level":"open_access","relation":"main_file","success":1,"file_size":3915000}],"abstract":[{"lang":"eng","text":"Sleep need is associated with both circuit dynamics and widespread synaptic plasticity, yet the specific synaptic changes underlying sleep homeostasis remain incompletely understood. In Drosophila, sleep loss has been shown to trigger plasticity of the presynaptic active zone, marked by increasing levels of the ELKS-family scaffold protein Bruchpilot (BRP). By titrating brp gene copy number, we previously established a presynapse-specific, dosage-dependent paradigm that modulates sleep pressure. Here, to elucidate the molecular landscape of this plasticity, we performed synapse-enriched integrated-omics. Proteomic and bioinformatic analyses revealed changes in immune and stress response pathways and local translation control. Strikingly, phospho-proteomic analysis uncovered a global shift toward hypophosphorylation, particularly in presynaptic proteins, indicating a reprogramming of the phosphorylation–dephosphorylation balance. This presynaptic hypophosphorylation is likely contributed by reduced activity of Protein Kinase A (PKA) and enhanced substrate affinity of Protein Phosphatase 1 (PP1) mediated by its regulatory subunit Spinophilin (Spn). Manipulating either PKA or PP1 activity was sufficient to suppress BRP-modulated sleep phenotypes. We propose that presynaptic hypophosphorylation constitutes a molecular signature of local synaptic remodeling that adaptively tunes sleep need via reversible posttranslational modification, a mechanism likely conserved across species."}],"article_number":"e2524065123","publication_status":"published","article_type":"original","publication":"Proceedings of the National Academy of Sciences","volume":123,"date_updated":"2026-08-20T05:35:33Z","pmid":1,"_id":"22733","citation":{"ama":"Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. Active zone plasticity couples sleep need to presynaptic hypophosphorylation. <i>Proceedings of the National Academy of Sciences</i>. 2026;123(24). doi:<a href=\"https://doi.org/10.1073/pnas.2524065123\">10.1073/pnas.2524065123</a>","mla":"Piao, Chengji, et al. “Active Zone Plasticity Couples Sleep Need to Presynaptic Hypophosphorylation.” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 24, e2524065123, National Academy of Sciences, 2026, doi:<a href=\"https://doi.org/10.1073/pnas.2524065123\">10.1073/pnas.2524065123</a>.","ista":"Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. 2026. Active zone plasticity couples sleep need to presynaptic hypophosphorylation. Proceedings of the National Academy of Sciences. 123(24), e2524065123.","short":"C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, S.J. Sigrist, Proceedings of the National Academy of Sciences 123 (2026).","ieee":"C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, and S. J. Sigrist, “Active zone plasticity couples sleep need to presynaptic hypophosphorylation,” <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 24. National Academy of Sciences, 2026.","apa":"Piao, C., Dutkiewicz, E., Kollipara, L., Sickmann, A., Huang, S., &#38; Sigrist, S. J. (2026). Active zone plasticity couples sleep need to presynaptic hypophosphorylation. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2524065123\">https://doi.org/10.1073/pnas.2524065123</a>","chicago":"Piao, Chengji, Ewelina Dutkiewicz, Laxmikanth Kollipara, Albert Sickmann, Sheng Huang, and Stephan J. Sigrist. “Active Zone Plasticity Couples Sleep Need to Presynaptic Hypophosphorylation.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2026. <a href=\"https://doi.org/10.1073/pnas.2524065123\">https://doi.org/10.1073/pnas.2524065123</a>."},"publication_identifier":{"issn":["0027-8424","1091-6490"]},"title":"Active zone plasticity couples sleep need to presynaptic hypophosphorylation","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"National Academy of Sciences","year":"2026"},{"DOAJ_listed":"1","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Springer Nature","title":"Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production","citation":{"ista":"Liu J, Zhai N, Zhang S, Tamada Y, Li T, Zhang L, Chen T, Wang C, Yang J, Gao J, Li X, Zhou J, Zhang Y, Liu Y, Wang Y, Friml J, Benková E, Li C, Xu L, Huang L. 2026. Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. Nature Communications. 17, 7994.","mla":"Liu, Juan, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature Communications</i>, vol. 17, 7994, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-74881-5\">10.1038/s41467-026-74881-5</a>.","ieee":"J. Liu <i>et al.</i>, “Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","short":"J. Liu, N. Zhai, S. Zhang, Y. Tamada, T. Li, L. Zhang, T. Chen, C. Wang, J. Yang, J. Gao, X. Li, J. Zhou, Y. Zhang, Y. Liu, Y. Wang, J. Friml, E. Benková, C. Li, L. Xu, L. Huang, Nature Communications 17 (2026).","apa":"Liu, J., Zhai, N., Zhang, S., Tamada, Y., Li, T., Zhang, L., … Huang, L. (2026). Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-74881-5\">https://doi.org/10.1038/s41467-026-74881-5</a>","chicago":"Liu, Juan, Ning Zhai, Shiyi Zhang, Yosuke Tamada, Tonghui Li, Linfan Zhang, Tong Chen, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-74881-5\">https://doi.org/10.1038/s41467-026-74881-5</a>.","ama":"Liu J, Zhai N, Zhang S, et al. Single-cell analyses identify the ginseng embryonic protoderm as a native compartment for high-efficiency ginsenoside production. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-74881-5\">10.1038/s41467-026-74881-5</a>"},"publication_identifier":{"eissn":["2041-1723"]},"date_updated":"2026-08-20T06:45:46Z","pmid":1,"_id":"22712","publication":"Nature Communications","volume":17,"abstract":[{"text":"Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside metabolites. However, the long cultivation cycle and susceptibility to diseases hinder the advancement of the ginseng industry. Here, we demonstrate that the embryonic protoderm of ginseng can efficiently produce ginsenosides. Single-cell transcriptome and mass spectrometry imaging analyses reveal that ginsenosides accumulate in the protoderm of ginseng embryonic callus (EC) at levels comparable to those in forest ginseng. Epigenetic analyses indicate that elevated histone acetylation and enhanced chromatin accessibility at regeneration- and ginsenoside metabolism-related gene loci are associated with the ginsenoside-producing capacity of EC. Increasing histone acetylation levels or overexpressing the regeneration-related WUSCHEL-RELATED HOMEOBOX11 (WOX11) gene further enhances ginsenoside production in EC. Our findings suggest that the protoderm of EC could serve as an in situ biological compartment for high-efficiency ginsenoside producion, offering a complementary approach to traditional ginseng cultivation.","lang":"eng"}],"article_type":"original","publication_status":"published","article_number":"7994","file":[{"file_id":"22742","checksum":"0b4ff29f0d0168b11be32a5f22ded9e4","file_name":"2026_NatureComm_Liu.pdf","file_size":2429551,"relation":"main_file","success":1,"access_level":"open_access","content_type":"application/pdf","date_updated":"2026-08-20T06:44:33Z","date_created":"2026-08-20T06:44:33Z","creator":"dernst"}],"ddc":["580"],"tmp":{"image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"date_created":"2026-08-16T22:01:42Z","type":"journal_article","das_tickbox":"1","doi":"10.1038/s41467-026-74881-5","file_date_updated":"2026-08-20T06:44:33Z","month":"08","language":[{"iso":"eng"}],"article_processing_charge":"Yes","researchdata_availability":"yes","scopus_import":"1","day":"07","has_accepted_license":"1","OA_place":"publisher","external_id":{"pmid":["42350386"]},"date_published":"2026-08-07T00:00:00Z","OA_type":"gold","oa":1,"oa_version":"Published Version","department":[{"_id":"JiFr"},{"_id":"EvBe"}],"status":"public","quality_controlled":"1","author":[{"last_name":"Liu","full_name":"Liu, Juan","first_name":"Juan"},{"full_name":"Zhai, Ning","last_name":"Zhai","first_name":"Ning"},{"first_name":"Shiyi","full_name":"Zhang, Shiyi","last_name":"Zhang"},{"last_name":"Tamada","full_name":"Tamada, Yosuke","first_name":"Yosuke"},{"first_name":"Tonghui","full_name":"Li, Tonghui","last_name":"Li"},{"first_name":"Linfan","last_name":"Zhang","full_name":"Zhang, Linfan"},{"first_name":"Tong","last_name":"Chen","full_name":"Chen, Tong"},{"first_name":"Chenglin","full_name":"Wang, Chenglin","last_name":"Wang"},{"last_name":"Yang","full_name":"Yang, Jian","first_name":"Jian"},{"last_name":"Gao","full_name":"Gao, Jiaqi","first_name":"Jiaqi"},{"first_name":"Xiang","full_name":"Li, Xiang","last_name":"Li","id":"4B7E523C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Junhui","last_name":"Zhou","full_name":"Zhou, Junhui"},{"first_name":"Yonghong","full_name":"Zhang, Yonghong","last_name":"Zhang"},{"id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu","full_name":"Liu, Yu","last_name":"Liu","orcid":"0000-0001-7313-6740"},{"first_name":"Yuan","last_name":"Wang","full_name":"Wang, Yuan"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","first_name":"Jiří"},{"full_name":"Benková, Eva","last_name":"Benková","orcid":"0000-0002-8510-9739","first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Chen","last_name":"Li","full_name":"Li, Chen"},{"first_name":"Lin","full_name":"Xu, Lin","last_name":"Xu"},{"last_name":"Huang","full_name":"Huang, Luqi","first_name":"Luqi"}],"supplementarymaterial":"yes","acknowledgement":"The authors are grateful to Professor Linfeng Li from the School of Life Science, Fudan University, for his assistance during the ginseng genome annotation. This work was supported by Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources (2060302-2401-08 to L.X. and J.L.), the National Natural Science Foundation of China (82373987 to J.L., 31701294 to L.X., 32225007 to L.X., and 32300285 to N.Z.), the Fundamental Research Funds for the Central public welfare research institutes (ZZ13-YQ-093, ZZXT202508 to J.L.), the CACMS Innovation Fund (CI2025G00-06 to J.L.), the Principle Investigator Program (HBMUPI202104 to Y.Z.), the Key R&D Program of Shandong Province, China (2024LZGC025 to L.X.), the National Key R&D Program of China (2024YFF1000700/2023YFE0101100 to L.X.), Strategic Priority Research Program of Chinese Academy of Sciences (XDB0630000 to L.X.), and China Postdoctoral Science Foundation (2023M733490 to N.Z.).","intvolume":"        17","dataavailabilitystatement":"The RNA-seq data generated in this study have been deposited in the GSA database under accession code CRA008967. The scRNA-seq data generated in this study have been deposited in the GSA database under accession code CRA026200. The ATAC-seq data generated in this study have been deposited in the GSA database under accession code CRA008969. The ChIP-seq data generated in this study have been deposited in the GSA database under accession code CRA008968. Single-cell RNA-seq data and scripts are publicly available on Zenodo (https://zenodo.org/records/20392012). Primers are in Supplemental Table 5. Source data are provided with this paper."},{"date_created":"2026-08-16T22:01:42Z","type":"journal_article","tmp":{"image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"ddc":["530"],"file":[{"file_id":"22741","file_name":"2026_NatureComm_Shi.pdf","checksum":"3f578b67037425a7c5d21922807b23df","success":1,"relation":"main_file","file_size":1790013,"access_level":"open_access","content_type":"application/pdf","date_updated":"2026-08-20T06:33:50Z","date_created":"2026-08-20T06:33:50Z","creator":"dernst"}],"abstract":[{"text":"When charge flows through a molecular circuit, it induces a magnetic field that allows the circuit to behave as a nanoscale electromagnet. However, in single-molecule circuits this magnetic field is usually weak. Here we show that radially π-conjugated carbon structures can support amplified circulating currents that generate local magnetic fields. Within tight-binding and density functional theory (DFT) frameworks, we first study cycloparaphenylene (CPP) junctions where both electrodes are attached to the same phenylene unit on the nanohoop. We observe an energy-dependent ring current component that traverses the whole macrocycle by mapping the local current density. Importantly, we find that destructive interference near degenerate resonances can reverse the ring current direction and amplify it strongly relative to the source–drain current. We show that this interference-driven design principle is general, and also carries over to C60 junctions. In fullerene, lower-lying degenerate resonances are more easily accessible through electrostatic gating, reaching a magnetic field of 14.2 mT under a 100 mV source–drain bias. This work thus provides new insights into ring currents in radially π-conjugated carbon structures and highlights their potential as design platforms for single-molecule electromagnets.","lang":"eng"}],"article_number":"7916","article_type":"original","publication_status":"published","publication":"Nature Communications","volume":17,"pmid":1,"date_updated":"2026-08-20T06:40:49Z","_id":"22711","citation":{"ista":"Shi W, Korytár R, Evers F, Tovar JD, Venkataraman L. 2026. Designing effective single-molecule electromagnets with radially π-conjugated carbon structures. Nature Communications. 17, 7916.","mla":"Shi, Wanzhuo, et al. “Designing Effective Single-Molecule Electromagnets with Radially π-Conjugated Carbon Structures.” <i>Nature Communications</i>, vol. 17, 7916, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-74365-6\">10.1038/s41467-026-74365-6</a>.","ieee":"W. Shi, R. Korytár, F. Evers, J. D. Tovar, and L. Venkataraman, “Designing effective single-molecule electromagnets with radially π-conjugated carbon structures,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","short":"W. Shi, R. Korytár, F. Evers, J.D. Tovar, L. Venkataraman, Nature Communications 17 (2026).","apa":"Shi, W., Korytár, R., Evers, F., Tovar, J. D., &#38; Venkataraman, L. (2026). Designing effective single-molecule electromagnets with radially π-conjugated carbon structures. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-74365-6\">https://doi.org/10.1038/s41467-026-74365-6</a>","chicago":"Shi, Wanzhuo, Richard Korytár, Ferdinand Evers, John D. Tovar, and Latha Venkataraman. “Designing Effective Single-Molecule Electromagnets with Radially π-Conjugated Carbon Structures.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-74365-6\">https://doi.org/10.1038/s41467-026-74365-6</a>.","ama":"Shi W, Korytár R, Evers F, Tovar JD, Venkataraman L. Designing effective single-molecule electromagnets with radially π-conjugated carbon structures. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-74365-6\">10.1038/s41467-026-74365-6</a>"},"publication_identifier":{"eissn":["2041-1723"]},"title":"Designing effective single-molecule electromagnets with radially π-conjugated carbon structures","publisher":"Springer Nature","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","DOAJ_listed":"1","year":"2026","dataavailabilitystatement":"The data generated in this study have been deposited in the Code Ocean capsule. The capsule contains the FHI-aims and AITRANSS output matrices used for post-processing, precomputed cache files, and optimized atomic coordinate files. These data are sufficient to reproduce the results reported in the paper. The code used to reproduce the local-current and magnetic-field analyses is available in the Code Ocean capsule. The capsule includes Python scripts for post-processing DFT output matrices and Mathematica notebooks for tight-binding calculations and reproducing visualizations.","intvolume":"        17","corr_author":"1","supplementarymaterial":"yes","acknowledgement":"The authors thank Jascha Repp from the University of Regensburg for helpful discussions. This paper is dedicated to the memory of Prof. Mark Ratner in appreciation of the encouragement offered many years ago, and whose influence had endured ever since. This work was supported by the National Science Foundation under grant NSF-DMR 2241180 and the Institute of Science and Technology Austria. The collaboration between L.V., R.K., and F.E. was supported by the Humboldt Foundation. This research was funded in part by the Austrian Science Fund (FWF) [10.55776/COE5] (Cluster of Excellence MECS).","author":[{"first_name":"Wanzhuo","last_name":"Shi","full_name":"Shi, Wanzhuo","id":"a3010425-87c8-11f0-8106-bec32bea74da"},{"first_name":"Richard","full_name":"Korytár, Richard","last_name":"Korytár"},{"last_name":"Evers","full_name":"Evers, Ferdinand","first_name":"Ferdinand"},{"first_name":"John D.","full_name":"Tovar, John D.","last_name":"Tovar"},{"first_name":"Latha","last_name":"Venkataraman","full_name":"Venkataraman, Latha","orcid":"0000-0002-6957-6089","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf"}],"status":"public","quality_controlled":"1","oa_version":"Published Version","department":[{"_id":"LaVe"}],"date_published":"2026-08-06T00:00:00Z","external_id":{"pmid":["42277037"]},"OA_type":"gold","oa":1,"has_accepted_license":"1","OA_place":"publisher","researchdata_availability":"yes","scopus_import":"1","article_processing_charge":"Yes","language":[{"iso":"eng"}],"day":"06","file_date_updated":"2026-08-20T06:33:50Z","month":"08","das_tickbox":"1","doi":"10.1038/s41467-026-74365-6"},{"date_created":"2026-08-12T16:12:19Z","type":"research_data","tmp":{"image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode"},"file":[{"creator":"fnapoli","content_type":"application/vnd.openxmlformats-officedocument.spreadsheetml.sheet","date_created":"2026-08-18T07:13:26Z","date_updated":"2026-08-18T07:13:26Z","relation":"main_file","success":1,"file_size":59096,"access_level":"open_access","file_id":"22725","file_name":"Pulse_parameters.xlsx","checksum":"dd23db23f7e75bafad6c67381163c1e2"},{"content_type":"application/zip","date_updated":"2026-08-18T07:16:00Z","date_created":"2026-08-18T07:16:00Z","creator":"fnapoli","file_id":"22726","file_name":"Scripts_submission.zip","checksum":"a7ad194d8d7f780725bc2c60c63d686d","success":1,"relation":"main_file","file_size":3591173,"access_level":"open_access"},{"access_level":"open_access","file_size":28750919,"relation":"main_file","success":1,"checksum":"dc099c298844973512ab224464964a1a","file_name":"FLYA_runs.zip","file_id":"22727","creator":"fnapoli","date_created":"2026-08-18T07:15:59Z","date_updated":"2026-08-18T07:15:59Z","content_type":"application/zip"},{"content_type":"application/zip","date_created":"2026-08-18T07:33:47Z","date_updated":"2026-08-18T07:33:47Z","creator":"fnapoli","file_id":"22728","file_name":"spectra_Bruker.zip","checksum":"04bcce8eb20c90089cbd2fb5e0c50a7f","relation":"main_file","success":1,"file_size":3824856998,"access_level":"open_access"},{"content_type":"application/zip","date_created":"2026-08-18T08:03:33Z","date_updated":"2026-08-18T08:03:33Z","creator":"fnapoli","file_id":"22729","file_name":"Titration_data.zip","checksum":"91c1161ca98632ed643d2b564395da5b","relation":"main_file","success":1,"file_size":17880653,"access_level":"open_access"},{"creator":"arashid","content_type":"text/plain","date_created":"2026-08-20T07:35:05Z","date_updated":"2026-08-20T07:35:05Z","file_size":868,"success":1,"relation":"main_file","access_level":"open_access","file_id":"22743","checksum":"ca2cf03b82656ae2858931d4391a3158","file_name":"README.txt"}],"abstract":[{"text":"Understanding enzyme function requires characterizing not only static structure but also dynamics and ligand interactions. NMR spectroscopy provides this insight at atomic resolution, yet for large proteins the difficulty of resonance assignment has largely confined such studies to systems below ∼50 kDa, or to observing only methyl groups. Here we present an integrated magic-angle spinning (MAS) and solution NMR study of the 134 kDa tetrameric malate dehydrogenase from Ignicoccus islandicus (IiMDH), an enzyme of particular interest as an evolutionary intermediate between allosteric lactate\r\ndehydrogenases and non-allosteric malate dehydrogenases. By combining high-dimensional (up to 4D) MAS NMR experiments on sedimented protein with solution NMR, we achieved 92% backbone heavy- atom assignment and 91% assignment of all Ile-δ1, Leu-δ1/-δ2, Val-γ1/-γ2, Met-ε and Thr-γ methyl groups. Building on these assignments, we use various probes of backbone and sidechain dynamics: elevated MAS NMR 15N rotating-frame relaxation (R1ρ) points to microsecond motions in functionally critical regions, including the catalytic loop and the mobile surface loop. Complementary methyl-axis order parameters from solution NMR identified additional flexible sites in the hydrophobic core. Chemical shift perturbation experiments upon addition of the substrate analogue oxamate, monitored via backbone 1H-15N TROSY, revealed both active-site contacts and responses in helices α2F and α3G, regions implicated in allosteric signal transmission. The integrated approach demonstrated here exploits the distinct strengths of MAS and solution NMR, and provides a comprehensive view of structure, dynamics, and substrate interactions in a large oligomeric enzyme that would not be accessible by either technique alone.","lang":"eng"}],"doi_confirm":"1","date_updated":"2026-08-20T07:40:15Z","_id":"22687","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"citation":{"short":"P. Schanda, F. Napoli, (2026).","ieee":"P. Schanda and F. Napoli, “Data and scripts for: ‘Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.’” Institute of Science and Technology Austria, 2026.","mla":"Schanda, Paul, and Federico Napoli. <i>Data and Scripts for: “Integrated Solid/Solution NMR Assignment Allows Mapping Dynamics and Ligand Binding in a 134 KDa Enzyme.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>.","ista":"Schanda P, Napoli F. 2026. Data and scripts for: ‘Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>.","chicago":"Schanda, Paul, and Federico Napoli. “Data and Scripts for: ‘Integrated Solid/Solution NMR Assignment Allows Mapping Dynamics and Ligand Binding in a 134 KDa Enzyme.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">https://doi.org/10.15479/AT-ISTA-22687</a>.","apa":"Schanda, P., &#38; Napoli, F. (2026). Data and scripts for: “Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22687\">https://doi.org/10.15479/AT-ISTA-22687</a>","ama":"Schanda P, Napoli F. Data and scripts for: “Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22687\">10.15479/AT-ISTA-22687</a>"},"title":"Data and scripts for: \"Integrated solid/solution NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme\"","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","publisher":"Institute of Science and Technology Austria","year":"2026","license":"https://creativecommons.org/licenses/by-nc/4.0/","corr_author":"1","acknowledgement":"This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra Rovó, Megha Mohan and Margarita Valhondo Falcón for excellent support of the NMR facility.","author":[{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","last_name":"Schanda","full_name":"Schanda, Paul","orcid":"0000-0002-9350-7606","first_name":"Paul"},{"id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","first_name":"Federico","orcid":"0000-0002-9043-136X","last_name":"Napoli","full_name":"Napoli, Federico"}],"status":"public","oa_version":"None","department":[{"_id":"PaSc"}],"contributor":[{"id":"d42e08e7-f4fc-11eb-af0a-d71e26138f1b","orcid":"0000-0002-9043-136X","contributor_type":"researcher","last_name":"Napoli","first_name":"Federico"},{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","last_name":"Schanda","contributor_type":"project_leader","orcid":"0000-0002-9350-7606","first_name":"Paul"},{"id":"a3089acd-6806-11ee-bacc-f0c7d500ad20","contributor_type":"project_member","last_name":"Singh","first_name":"Rajkumar"},{"id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471","contributor_type":"project_member","last_name":"Kapitonova","first_name":"Anna"},{"contributor_type":"project_member","last_name":"Aitenbichler","first_name":"Virgil"},{"id":"334a5e40-8747-11f0-b671-ba1f5154b4b4","contributor_type":"project_member","last_name":"Toscano","first_name":"Giorgia"},{"first_name":"Barbara","last_name":"Perrone","contributor_type":"data_collector"}],"date_published":"2026-08-20T00:00:00Z","project":[{"_id":"eb9c82eb-77a9-11ec-83b8-aadd536561cf","name":"AlloSpace. The emergence and mechanisms of allostery","grant_number":"I05812"}],"oa":1,"has_accepted_license":"1","OA_place":"repository","article_processing_charge":"No","day":"20","file_date_updated":"2026-08-20T07:35:05Z","month":"08","doi":"10.15479/AT-ISTA-22687"},{"related_material":{"record":[{"id":"22667","relation":"dissertation_contains","status":"public"}]},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"file":[{"creator":"dernst","date_updated":"2026-05-04T12:20:10Z","date_created":"2026-05-04T12:20:10Z","content_type":"application/pdf","access_level":"open_access","file_size":14925958,"relation":"main_file","success":1,"checksum":"0d26cdb5b8d8dec3a911d8261a65cdef","file_name":"2026_CellReports_Vijatovic.pdf","file_id":"21795"}],"ddc":["570"],"type":"journal_article","date_created":"2026-04-19T22:07:43Z","volume":45,"publication":"Cell Reports","article_number":"117227","publication_status":"published","article_type":"original","abstract":[{"lang":"eng","text":"As vertebrates transitioned from water to land, locomotion shifted from undulatory swimming to limb-based movement. How spinal circuits and their cell types evolved to support this transition remains unclear. We leverage frog metamorphosis, which recapitulates this transition within a single organism, to define how spinal circuits generate aquatic versus terrestrial motor patterns. At swim stages, spinal architecture is uniform, with a transcriptionally and anatomically homogeneous motor and interneurons. As limbs develop and their movement complexifies, spinal circuits expand in neuron number and subtype diversity. This expansion is most pronounced for V1 inhibitory neurons, which increase ∼70-fold and diversify into transcriptionally distinct subtypes. Disrupting transcription factors defining emerging motor and V1 populations reveals molecular segregation between swim and limb circuits, highlighting the role of subtype diversity in motor coordination. A multifold increase in inhibitory neuron diversity thus underlies the tail-to-limb locomotor transition, providing a framework for spinal circuit adaptation during vertebrate evolution."}],"publication_identifier":{"eissn":["2211-1247"],"issn":["2639-1856"]},"citation":{"ama":"Vijatovic D, Toma FA, Ignatyev Y, et al. Multifold increase in spinal inhibitory cell types with emergence of limb movement. <i>Cell Reports</i>. 2026;45(4). doi:<a href=\"https://doi.org/10.1016/j.celrep.2026.117227\">10.1016/j.celrep.2026.117227</a>","ieee":"D. Vijatovic <i>et al.</i>, “Multifold increase in spinal inhibitory cell types with emergence of limb movement,” <i>Cell Reports</i>, vol. 45, no. 4. Elsevier, 2026.","short":"D. Vijatovic, F.A. Toma, Y. Ignatyev, Z.P. Harrington, C.M. Sommer, R. Hauschild, M.G. Smits, M. Dalla Vecchia, A.J. Trevisan, P. Chapman, M. Julseth, S. Brenner-Morton, M.I. Gabitto, J.S. Dasen, J.B. Bikoff, L.B. Sweeney, Cell Reports 45 (2026).","mla":"Vijatovic, David, et al. “Multifold Increase in Spinal Inhibitory Cell Types with Emergence of Limb Movement.” <i>Cell Reports</i>, vol. 45, no. 4, 117227, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.celrep.2026.117227\">10.1016/j.celrep.2026.117227</a>.","ista":"Vijatovic D, Toma FA, Ignatyev Y, Harrington ZP, Sommer CM, Hauschild R, Smits MG, Dalla Vecchia M, Trevisan AJ, Chapman P, Julseth M, Brenner-Morton S, Gabitto MI, Dasen JS, Bikoff JB, Sweeney LB. 2026. Multifold increase in spinal inhibitory cell types with emergence of limb movement. Cell Reports. 45(4), 117227.","chicago":"Vijatovic, David, Florina Alexandra  Toma, Y Ignatyev, Zoe P Harrington, Christoph M Sommer, Robert Hauschild, Matthijs Geert Smits, et al. “Multifold Increase in Spinal Inhibitory Cell Types with Emergence of Limb Movement.” <i>Cell Reports</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.celrep.2026.117227\">https://doi.org/10.1016/j.celrep.2026.117227</a>.","apa":"Vijatovic, D., Toma, F. A., Ignatyev, Y., Harrington, Z. P., Sommer, C. M., Hauschild, R., … Sweeney, L. B. (2026). Multifold increase in spinal inhibitory cell types with emergence of limb movement. <i>Cell Reports</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.celrep.2026.117227\">https://doi.org/10.1016/j.celrep.2026.117227</a>"},"acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"_id":"21746","pmid":1,"date_updated":"2026-08-20T14:45:18Z","year":"2026","DOAJ_listed":"1","title":"Multifold increase in spinal inhibitory cell types with emergence of limb movement","publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","acknowledgement":"We would like to thank the members of the Sweeney Lab, Mario de Bono, Michael Forsthofer, Katharina Lust, and Meital Oren, for comments on the manuscript. We are also grateful to Tom Jessell and Chris Kintner for their scientific insight and mentorship during the conception of this project. It would also have not been possible without the technical support of the Aquatics and Imaging and Optics Facility support teams (ISTA). We thank Martin Estermann for preparing the initial draft of the graphical abstract and Niki Barolini for the final version. In addition, we thank our funding sources for providing the resources to do these experiments: GFF NÖ FTI Strategy Lower Austria dissertation grant FT121-D-046 (to D.V.), Horizon Europe ERC starting grant 101041551 (to Y.I., L.B.S., F.A.T., and D.V.), Special Research Program (SFB) of the Austrian Science Fund (FWF) project F7814-B (to L.B.S.), Austrian Science Fund (FWF) 10.55776/COE16 (to Y.I. and L.B.S.), NINDS 5R35NS116858 (to J.S.D.), CZI grant DAF2020-225401 (DOI) 10.37921/120055ratwvi (to R.H.), NIH grant R01NS123116 (to J.B.B.), American Lebanese Syrian Associated Charities (ALSAC) (to J.B.B.), German Academic Exchange Service (DAAD) IFI grant 57515251-91853472 (to Z.H.), and Project A.L.S. (to S.B.-M.).","author":[{"first_name":"David","orcid":"0000-0002-5494-0941","full_name":"Vijatovic, David","last_name":"Vijatovic","id":"cf391e77-ec3c-11ea-a124-d69323410b58"},{"id":"2f73f876-f128-11eb-9611-b96b5a30cb0e","first_name":"Florina Alexandra ","full_name":"Toma, Florina Alexandra ","last_name":"Toma"},{"first_name":"Y","last_name":"Ignatyev","full_name":"Ignatyev, Y"},{"first_name":"Zoe P","orcid":"0009-0008-0158-4032","last_name":"Harrington","full_name":"Harrington, Zoe P","id":"a8144562-32c9-11ee-b5ce-d9800628bda2"},{"id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","full_name":"Sommer, Christoph M","last_name":"Sommer","orcid":"0000-0003-1216-9105","first_name":"Christoph M"},{"id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","full_name":"Hauschild, Robert","last_name":"Hauschild","orcid":"0000-0001-9843-3522","first_name":"Robert"},{"id":"7a231d52-e216-11ee-a0bb-8acd55f8f1f0","first_name":"Matthijs Geert","last_name":"Smits","full_name":"Smits, Matthijs Geert"},{"last_name":"Dalla Vecchia","full_name":"Dalla Vecchia, Marco","first_name":"Marco","id":"02a7a869-ff06-11ed-a87f-86649d6077e5"},{"first_name":"Alexandra J.","last_name":"Trevisan","full_name":"Trevisan, Alexandra J."},{"last_name":"Chapman","full_name":"Chapman, Phillip","first_name":"Phillip"},{"last_name":"Julseth","full_name":"Julseth, Mara","first_name":"Mara","id":"1cf464b2-dc7d-11ea-9b2f-f9b1aa9417d1"},{"last_name":"Brenner-Morton","full_name":"Brenner-Morton, Susan","first_name":"Susan"},{"first_name":"Mariano I.","last_name":"Gabitto","full_name":"Gabitto, Mariano I."},{"first_name":"Jeremy S.","full_name":"Dasen, Jeremy S.","last_name":"Dasen"},{"first_name":"Jay B.","last_name":"Bikoff","full_name":"Bikoff, Jay B."},{"first_name":"Lora Beatrice Jaeger","full_name":"Sweeney, Lora Beatrice Jaeger","last_name":"Sweeney","orcid":"0000-0001-9242-5601","id":"56BE8254-C4F0-11E9-8E45-0B23E6697425"}],"intvolume":"        45","oa":1,"OA_type":"gold","date_published":"2026-04-28T00:00:00Z","project":[{"grant_number":"101041551","name":"Development and Evolution of Tetrapod Motor Circuits","_id":"ebb66355-77a9-11ec-83b8-b8ac210a4dae"},{"grant_number":"F7814","name":"Stem Cell Modulation in Neural Development and Regeneration/ P14-Swim-to-limb transition: cell type to connection diversity","_id":"8da85f50-16d5-11f0-9cad-eab8b0ff6c9e"},{"grant_number":"CZI01","_id":"c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473","name":"Tools for automation and feedback microscopy"},{"_id":"bd73af52-d553-11ed-ba76-912049f0ac7a","name":"Development of V1 interneuron diversity during swim-to-walk transition of Xenopus metamorphosis","grant_number":"FTI21-D-046"}],"external_id":{"pmid":["41964955 "]},"status":"public","quality_controlled":"1","oa_version":"Published Version","department":[{"_id":"LoSw"},{"_id":"GradSch"},{"_id":"TiVo"},{"_id":"Bio"},{"_id":"NiBa"}],"day":"28","scopus_import":"1","language":[{"iso":"eng"}],"article_processing_charge":"Yes","OA_place":"publisher","issue":"4","has_accepted_license":"1","doi":"10.1016/j.celrep.2026.117227","month":"04","PlanS_conform":"1","file_date_updated":"2026-05-04T12:20:10Z"},{"month":"08","file_date_updated":"2026-08-12T13:44:36Z","doi":"10.15479/AT-ISTA-22667","OA_place":"publisher","has_accepted_license":"1","day":"10","language":[{"iso":"eng"}],"article_processing_charge":"No","oa_version":"Published Version","department":[{"_id":"GradSch"},{"_id":"LoSw"}],"status":"public","project":[{"name":"Development and Evolution of Tetrapod Motor Circuits","_id":"ebb66355-77a9-11ec-83b8-b8ac210a4dae","grant_number":"101041551"},{"name":"Development of V1 interneuron diversity during swim-to-walk transition of Xenopus metamorphosis","_id":"bd73af52-d553-11ed-ba76-912049f0ac7a","grant_number":"FTI21-D-046"},{"name":"Development of Viral Vectors for Amphibian Gene Delivery and Manipulation","_id":"34a02c70-11ca-11ed-8bc3-fbfd2c86c88f","grant_number":"3(GG016346-01)"}],"date_published":"2026-08-10T00:00:00Z","alternative_title":["ISTA Thesis"],"page":"172","author":[{"first_name":"David","orcid":"0000-0002-5494-0941","full_name":"Vijatovic, David","last_name":"Vijatovic","id":"cf391e77-ec3c-11ea-a124-d69323410b58"}],"corr_author":"1","acknowledgement":"I am also grateful for the financial support that made this work possible, including the\r\nEuropean Research Council (ERC Starting Grant 101041551), the Austrian Science\r\nFund (FWF, Cluster of Excellence 10.55776/COE16), the GFF Lower Austria FTI\r\nStrategy Dissertation Fellowship (FTI21-D-046), and the FENS/IBRO-PERC\r\nExchange Fellowship. ","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publisher":"Institute of Science and Technology Austria","title":"Dissecting the molecular and functional basis of motor control in the frog Xenopus laevis","supervisor":[{"id":"56BE8254-C4F0-11E9-8E45-0B23E6697425","first_name":"Lora Beatrice Jaeger","orcid":"0000-0001-9242-5601","full_name":"Sweeney, Lora Beatrice Jaeger","last_name":"Sweeney"}],"year":"2026","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"_id":"22667","date_updated":"2026-08-20T14:45:18Z","publication_identifier":{"isbn":["978-3-99078-082-4"],"issn":["2663-337X"]},"citation":{"short":"D. Vijatovic, Dissecting the Molecular and Functional Basis of Motor Control in the Frog Xenopus Laevis, Institute of Science and Technology Austria, 2026.","ieee":"D. Vijatovic, “Dissecting the molecular and functional basis of motor control in the frog Xenopus laevis,” Institute of Science and Technology Austria, 2026.","ista":"Vijatovic D. 2026. Dissecting the molecular and functional basis of motor control in the frog Xenopus laevis. Institute of Science and Technology Austria.","mla":"Vijatovic, David. <i>Dissecting the Molecular and Functional Basis of Motor Control in the Frog Xenopus Laevis</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22667\">10.15479/AT-ISTA-22667</a>.","chicago":"Vijatovic, David. “Dissecting the Molecular and Functional Basis of Motor Control in the Frog Xenopus Laevis.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22667\">https://doi.org/10.15479/AT-ISTA-22667</a>.","apa":"Vijatovic, D. (2026). <i>Dissecting the molecular and functional basis of motor control in the frog Xenopus laevis</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22667\">https://doi.org/10.15479/AT-ISTA-22667</a>","ama":"Vijatovic D. Dissecting the molecular and functional basis of motor control in the frog Xenopus laevis. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22667\">10.15479/AT-ISTA-22667</a>"},"publication_status":"published","doi_confirm":"1","degree_awarded":"PhD","type":"dissertation","date_created":"2026-08-10T13:44:30Z","file":[{"creator":"dvijatov","date_created":"2026-08-10T13:35:39Z","date_updated":"2026-08-10T13:35:39Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","relation":"source_file","file_size":14322760,"file_name":"2026_Vijatovic_David_Thesis.docx","checksum":"e3acfea4b1a3abf99e74224656740a15","file_id":"22669"},{"content_type":"application/pdf","date_created":"2026-08-12T13:44:36Z","date_updated":"2026-08-12T13:44:36Z","embargo_to":"open_access","creator":"dvijatov","embargo":"2027-08-10","file_id":"22695","file_name":"2026_Vijatovic_David_Thesis.pdf","checksum":"dc8c78ae14f69e54faa41e65db5c6402","relation":"main_file","file_size":116926375,"access_level":"closed"}],"ddc":["573"],"related_material":{"record":[{"relation":"part_of_dissertation","id":"21746","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"15016"}]}},{"alternative_title":["ISTA Thesis"],"page":"187","corr_author":"1","author":[{"first_name":"Miguel","orcid":"0000-0002-2505-4246","last_name":"Cueto Noval","full_name":"Cueto Noval, Miguel","id":"ffc563a3-f6e0-11ea-865d-e3cce03d17cc"}],"status":"public","oa_version":"Published Version","department":[{"_id":"GradSch"},{"_id":"KrPi"}],"oa":1,"date_published":"2026-08-10T00:00:00Z","OA_place":"publisher","has_accepted_license":"1","day":"10","article_processing_charge":"No","language":[{"iso":"eng"}],"month":"08","file_date_updated":"2026-08-19T11:36:46Z","doi":"10.15479/AT-ISTA-22664","type":"dissertation","date_created":"2026-08-10T10:18:35Z","tmp":{"image":"/images/cc_by_nc_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"related_material":{"record":[{"relation":"part_of_dissertation","id":"14691","status":"public"},{"status":"public","id":"18702","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"21262"}]},"ddc":["000"],"file":[{"date_updated":"2026-08-19T11:36:46Z","date_created":"2026-08-13T09:39:00Z","content_type":"application/pdf","creator":"mcuetono","file_name":"2026_CuetoNoval_Miguel_Thesis.pdf","checksum":"d61beeb9a250a04396c2c61bbd0783aa","file_id":"22702","access_level":"open_access","relation":"main_file","file_size":1390255},{"creator":"mcuetono","date_updated":"2026-08-14T10:26:06Z","date_created":"2026-08-13T09:39:01Z","content_type":"application/zip","access_level":"closed","relation":"source_file","file_size":9923509,"file_name":"2026_CuetoNoval_Miguel_Thesis.zip","checksum":"4d6def422cc93a108faf5e5defc0f807","file_id":"22703"}],"doi_confirm":"1","publication_status":"published","abstract":[{"lang":"eng","text":"The widespread adoption of apps like Whatsapp and Signal has translated into billions of people all around the world communicating on a regular basis by making use of services that offer end-to-end encryption and even provide security guarantees when a user's device is compromised.\r\n\r\nThis was made possible by the introduction of the Double Ratchet Algorithm~\\cite{double_ratchet}, which was designed for a setting where communication takes place between two parties.\r\nHowever, in practice, many apps offer the possibility of creating groups.\r\nThe protocols they use to secure communication are inefficient for large group which has the undesireable consequence that the aforementioned apps have established limits on the group size of roughly 1000 users.\r\nThis has motivated the introduction of the Messaging Layer Security (MLS) standard~\\cite{rfc9420} by the IETF which is based on a primitive called Continuous Group Key Agreement (CGKA)~\\cite{C:ACDT20}.\r\n\r\nThis primitive allows a group of users to maintain a shared secret key that is frequently rotated by the group members in order to change group membership, achieve forward secrecy (FS) and post compromise security (PCS).\r\nMost protocols are based on binary trees where the nodes are associated to a pair formed by public key and a secret key.\r\nEach leaf corresponds to one of the group members and a user knows the secret keys associated to nodes along the path from their leaf to the root.\r\nWhen a user wants to update their key material they have to change $ \\log(N) $ many keys.\r\nThis requires uploading $ \\log(N) $ many ciphertexts to communicate the new keys to the rest of the group members in a way that respects the tree structure.\r\n\r\nIn this thesis we study how much communication between group members is required in order to add and remove users from a group as well as in order to provide PCS when we consider CGKAs built using standard cryptographic primitives like pseudo-random functions and public-key encryption. Furthermore, we also consider the case of MLS and provide the first lower bound showing that its communication complexity is much worse than previously believed, i.e., it is very far from $ \\log(N) $.\r\nFinally, we also propose a variant of MLS which provably achieves the same security properties with a much lower communication cost."}],"degree_awarded":"PhD","_id":"22664","date_updated":"2026-08-21T10:53:17Z","publication_identifier":{"isbn":[" 978-3-99078-087-9"],"issn":["2663-337X"]},"citation":{"ama":"Cueto Noval M. Towards efficient secure group messaging. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22664\">10.15479/AT-ISTA-22664</a>","apa":"Cueto Noval, M. (2026). <i>Towards efficient secure group messaging</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22664\">https://doi.org/10.15479/AT-ISTA-22664</a>","chicago":"Cueto Noval, Miguel. “Towards Efficient Secure Group Messaging.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22664\">https://doi.org/10.15479/AT-ISTA-22664</a>.","ista":"Cueto Noval M. 2026. Towards efficient secure group messaging. Institute of Science and Technology Austria.","mla":"Cueto Noval, Miguel. <i>Towards Efficient Secure Group Messaging</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22664\">10.15479/AT-ISTA-22664</a>.","ieee":"M. Cueto Noval, “Towards efficient secure group messaging,” Institute of Science and Technology Austria, 2026.","short":"M. Cueto Noval, Towards Efficient Secure Group Messaging, Institute of Science and Technology Austria, 2026."},"title":"Towards efficient secure group messaging","publisher":"Institute of Science and Technology Austria","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","year":"2026","supervisor":[{"first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87"}],"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/"},{"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"20563"}]},"file":[{"creator":"dernst","content_type":"application/pdf","date_updated":"2026-07-23T05:55:03Z","date_created":"2026-07-23T05:55:03Z","file_size":612317,"success":1,"relation":"main_file","access_level":"open_access","file_id":"22386","checksum":"d038f4d00cbfbde2672c17138eab21c9","file_name":"2026_EuropJourAppliedMath_Portinale.pdf"}],"ddc":["500"],"date_created":"2024-12-23T11:03:59Z","type":"journal_article","keyword":["optimal transport","discrete-to-continuum","homogenisation","linear growth","gamma-convergence"],"publication":"European Journal of Applied Mathematics","volume":37,"abstract":[{"lang":"eng","text":"We prove discrete-to-continuum convergence for dynamical optimal transport on  Zd\r\n -periodic graphs with cost functional having linear growth at infinity. This result provides an answer to a problem left open by Gladbach, Kopfer, Maas, and Portinale (Calc Var Partial Differential Equations 62(5), 2023), where the convergence behaviour of discrete boundary-value dynamical transport problems is proved under the stronger assumption of superlinear growth. Our result extends the known literature to some important classes of examples, such as scaling limits of  1 -Wasserstein transport problems. Similarly to what happens in the quadratic case, the geometry of the graph plays a crucial role in the structure of the limit cost function, as we discuss in the final part of this work, which includes some visual representations."}],"publication_status":"published","article_type":"original","citation":{"ama":"Portinale L, Quattrocchi F. Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. <i>European Journal of Applied Mathematics</i>. 2026;37(3):614-642. doi:<a href=\"https://doi.org/10.1017/s0956792524000810\">10.1017/s0956792524000810</a>","chicago":"Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal of Applied Mathematics</i>. Cambridge University Press, 2026. <a href=\"https://doi.org/10.1017/s0956792524000810\">https://doi.org/10.1017/s0956792524000810</a>.","apa":"Portinale, L., &#38; Quattrocchi, F. (2026). Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. <i>European Journal of Applied Mathematics</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/s0956792524000810\">https://doi.org/10.1017/s0956792524000810</a>","ieee":"L. Portinale and F. Quattrocchi, “Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs,” <i>European Journal of Applied Mathematics</i>, vol. 37, no. 3. Cambridge University Press, pp. 614–642, 2026.","short":"L. Portinale, F. Quattrocchi, European Journal of Applied Mathematics 37 (2026) 614–642.","mla":"Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal of Applied Mathematics</i>, vol. 37, no. 3, Cambridge University Press, 2026, pp. 614–42, doi:<a href=\"https://doi.org/10.1017/s0956792524000810\">10.1017/s0956792524000810</a>.","ista":"Portinale L, Quattrocchi F. 2026. Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs. European Journal of Applied Mathematics. 37(3), 614–642."},"publication_identifier":{"issn":["0956-7925"],"eissn":["1469-4425"]},"date_updated":"2026-08-25T22:31:05Z","_id":"18706","DOAJ_listed":"1","year":"2026","title":"Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs","publisher":"Cambridge University Press","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"L.P. gratefully acknowledges fundings from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – GZ 2047/1, Projekt-ID 390685813. F.Q. gratefully acknowledges support from the Austrian Science Fund (FWF) project 10.55776/F65.","supplementarymaterial":"no","author":[{"full_name":"Portinale, Lorenzo","last_name":"Portinale","first_name":"Lorenzo","id":"30AD2CBC-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Quattrocchi, Filippo","last_name":"Quattrocchi","orcid":"0009-0000-9773-1931","first_name":"Filippo","id":"3ebd6ba8-edfb-11eb-afb5-91a9745ba308"}],"page":"614-642","intvolume":"        37","isi":1,"date_published":"2026-06-01T00:00:00Z","external_id":{"isi":["001381435800001"]},"project":[{"_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504"}],"OA_type":"gold","oa":1,"status":"public","quality_controlled":"1","oa_version":"Published Version","department":[{"_id":"GradSch"},{"_id":"JaMa"}],"scopus_import":"1","researchdata_availability":"no","language":[{"iso":"eng"}],"article_processing_charge":"Yes","day":"01","has_accepted_license":"1","OA_place":"publisher","issue":"3","das_tickbox":"0","doi":"10.1017/s0956792524000810","file_date_updated":"2026-07-23T05:55:03Z","PlanS_conform":"1","month":"06"},{"OA_place":"publisher","has_accepted_license":"1","day":"05","language":[{"iso":"eng"}],"article_processing_charge":"No","month":"08","file_date_updated":"2026-08-14T11:42:42Z","doi":"10.15479/AT-ISTA-22694","alternative_title":["ISTA Thesis"],"page":"185","author":[{"full_name":"Löwit, Jakub","last_name":"Löwit","first_name":"Jakub","id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0"}],"acknowledgement":"It was funded by a DOC Fellowship of the Austrian Academy of Sciences entitled Arithmetic,\r\ngeometry, topology and representation theory arising from the affine Grassmannian. It was\r\nfurther funded by the Austrian Science Fund FWF 10.55776/P35847, and an Erasmus+ staff\r\nmobility training. \r\n","corr_author":"1","department":[{"_id":"GradSch"},{"_id":"TaHa"}],"oa_version":"Published Version","status":"public","oa":1,"project":[{"_id":"901e2a43-16d5-11f0-9cad-9cead34748d6","name":"Arithmetic, geometry, topology and representation theory arising from the affine Grassmannian","grant_number":"27004"},{"grant_number":"P35847","name":"Geometry of the tip of the global nilpotent cone","_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3"}],"date_published":"2026-08-05T00:00:00Z","_id":"22694","date_updated":"2026-08-26T06:53:55Z","publication_identifier":{"issn":["2663-337X"]},"citation":{"apa":"Löwit, J. (2026). <i>Equivariant K-theory of affine Grassmannians in representation theory and arithmetic</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-22694\">https://doi.org/10.15479/AT-ISTA-22694</a>","chicago":"Löwit, Jakub. “Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-22694\">https://doi.org/10.15479/AT-ISTA-22694</a>.","mla":"Löwit, Jakub. <i>Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22694\">10.15479/AT-ISTA-22694</a>.","ista":"Löwit J. 2026. Equivariant K-theory of affine Grassmannians in representation theory and arithmetic. Institute of Science and Technology Austria.","ieee":"J. Löwit, “Equivariant K-theory of affine Grassmannians in representation theory and arithmetic,” Institute of Science and Technology Austria, 2026.","short":"J. Löwit, Equivariant K-Theory of Affine Grassmannians in Representation Theory and Arithmetic, Institute of Science and Technology Austria, 2026.","ama":"Löwit J. Equivariant K-theory of affine Grassmannians in representation theory and arithmetic. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-22694\">10.15479/AT-ISTA-22694</a>"},"publisher":"Institute of Science and Technology Austria","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","title":"Equivariant K-theory of affine Grassmannians in representation theory and arithmetic","year":"2026","supervisor":[{"id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","last_name":"Hausel","full_name":"Hausel, Tamás","orcid":"0000-0002-9582-2634","first_name":"Tamás"}],"type":"dissertation","date_created":"2026-08-12T14:05:36Z","ddc":["510","516","512","514","513"],"file":[{"access_level":"open_access","relation":"main_file","file_size":1574709,"file_name":"2026_Löwit_Jakub_Thesis.pdf","checksum":"2d0be77791dc296621c6c0f76be9d0d7","file_id":"22709","creator":"jloewit","date_created":"2026-08-14T11:42:31Z","date_updated":"2026-08-14T11:42:31Z","content_type":"application/pdf"},{"relation":"source_file","file_size":1085118,"access_level":"closed","file_id":"22710","file_name":"2026_Löwit_Jakub_Source_files.zip","checksum":"61bde4b58c1e6c7baeb561e41f82659b","creator":"jloewit","content_type":"application/zip","date_created":"2026-08-14T11:42:42Z","date_updated":"2026-08-14T11:42:42Z"}],"related_material":{"record":[{"status":"public","id":"21751","relation":"part_of_dissertation"},{"id":"22693","relation":"part_of_dissertation","status":"public"}]},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"publisher_comment":"For open access purposes, the author has applied a CC BY public copyright\r\nlicense to any author-accepted manuscript version arising from this submission.","publication_status":"published","doi_confirm":"1","abstract":[{"lang":"eng","text":"We develop and employ techniques from equivariant algebraic K-theory and related invariants\r\nin the context of geometric representation theory, in both arithmetic and topological situations.\r\nWe showcase the use of such techniques on the affine Grassmannian Gr, a space of fundamental\r\ninterest in the geometric Langlands program.\r\n\r\nIt is a deep development of mathematics of the last century that many concrete, yet combina-\r\ntorially complex algebraic problems may be effectively studied through the lens of algebraic\r\ngeometry. The objects of interest can be often realized as cohomological invariants of algebraic\r\nvarieties, and good understanding of their geometry sheds light into the original questions.\r\nSuch techniques have seen immense applications in the Langlands program, where they go\r\nunder the label of geometric representation theory.\r\n\r\nOne source of powerful invariants in algebraic geometry comes from algebraic K-theory,\r\nHochschild homology, and their relatives. These localizing invariants contain large amount\r\nof information, but are quite hard to compute. For this reason, their usage in geometric\r\nrepresentation theory has been limited.\r\n\r\nThe aim of this thesis is to showcase how to control such invariants in the situations of\r\ninterest and use them to obtain new insights. We start by reinterpreting equivariant Hochschild\r\nhomology in terms of functions on certain fixed-point schemes, which are of independent\r\ninterest. We compare it to equivariant K-theory via the trace map. We give new computations\r\nand comparisons of such invariants of affine Schubert varieties in Gr, including arithmetic\r\nsituations. We show that they behave much better than expected.\r\n\r\nWe finally utilize this circle of ideas in a purely topological setting. We describe the varying\r\nfixed points of the extended torus action on the affine Grassmannian, and use it to compute\r\nits equivariant topological K-theory ring. The answer is nontrivial and verifies an outstanding\r\nconjecture in the subject.\r\n\r\nWe compare, partly conjecturally, the resulting K-theory ring to the completed center of an\r\nintegral even hybrid quantum group and its deformed quantum category O. This gives a\r\ngenuine application of our computations in pure representation theory."}],"degree_awarded":"PhD"},{"year":"2026","publisher":"Oxford University Press","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Equivariant localizing invariants of simple varieties","citation":{"ama":"Löwit J. Equivariant localizing invariants of simple varieties. <i>International Mathematics Research Notices</i>. 2026;2026(7). doi:<a href=\"https://doi.org/10.1093/imrn/rnag058\">10.1093/imrn/rnag058</a>","short":"J. Löwit, International Mathematics Research Notices 2026 (2026).","ieee":"J. Löwit, “Equivariant localizing invariants of simple varieties,” <i>International Mathematics Research Notices</i>, vol. 2026, no. 7. Oxford University Press, 2026.","ista":"Löwit J. 2026. Equivariant localizing invariants of simple varieties. International Mathematics Research Notices. 2026(7), rnag058.","mla":"Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” <i>International Mathematics Research Notices</i>, vol. 2026, no. 7, rnag058, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/imrn/rnag058\">10.1093/imrn/rnag058</a>.","chicago":"Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/imrn/rnag058\">https://doi.org/10.1093/imrn/rnag058</a>.","apa":"Löwit, J. (2026). Equivariant localizing invariants of simple varieties. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rnag058\">https://doi.org/10.1093/imrn/rnag058</a>"},"publication_identifier":{"eissn":["1687-0247"],"issn":["1073-7928"]},"date_updated":"2026-08-26T06:53:54Z","_id":"21751","publication":"International Mathematics Research Notices","volume":2026,"abstract":[{"lang":"eng","text":"We define a certain class of simple varieties over a field k by a constructive recipe and show how to control their (equivariant) truncating invariants. Consequently, we prove that on simple varieties: (i) if k = k and char k = p, the p-adic cyclotomic trace is an equivalence; (ii) if k = Q, the Goodwillie–Jones trace is an isomorphism in degree zero; (iii) we can control homotopy invariant K-theory KH, which is equivariantly formal and determined by its topological counterparts. Simple varieties are quite special, but encompass important singular examples appearing in geometric representation theory. We, in particular, show that both finite and affine Schubert varieties for GLn lie in this class, so all the above results hold for them. "}],"article_type":"original","publication_status":"published","article_number":"rnag058","ddc":["510"],"file":[{"creator":"dernst","content_type":"application/pdf","date_updated":"2026-05-06T06:35:05Z","date_created":"2026-05-06T06:35:05Z","relation":"main_file","success":1,"file_size":1663246,"access_level":"open_access","file_id":"21803","file_name":"2026_IMRN_Loewit.pdf","checksum":"306f4567b7b2dcf38e23f7b55a27514e"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"22694"}]},"date_created":"2026-04-19T22:07:48Z","type":"journal_article","doi":"10.1093/imrn/rnag058","file_date_updated":"2026-05-06T06:35:05Z","PlanS_conform":"1","month":"04","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","scopus_import":"1","day":"01","has_accepted_license":"1","issue":"7","OA_place":"publisher","project":[{"grant_number":"27004","_id":"901e2a43-16d5-11f0-9cad-9cead34748d6","name":"Arithmetic, geometry, topology and representation theory arising from the affine Grassmannian"}],"external_id":{"arxiv":["2507.09392"]},"date_published":"2026-04-01T00:00:00Z","OA_type":"hybrid","oa":1,"oa_version":"Published Version","department":[{"_id":"TaHa"}],"status":"public","quality_controlled":"1","author":[{"first_name":"Jakub","full_name":"Löwit, Jakub","last_name":"Löwit","id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0"}],"acknowledgement":"This work was supported by a DOC Fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (ISTA) and by an Erasmus+ staff mobility training. It took place during the author’s visit to Laboratoire de Mathématiques d’Orsay in the course of his PhD at the Institute of Science and Technology Austria. First and foremost, I would like to thank Matthew Morrow for discussions, explanations and ideas without which this work would not have been carried out. I would further like to thank Brian Conrad for providing an amazing reference on projective cones in appropriate generality, to Vova Sosnilo for carefully discussing – among other things – the derived nilinvariance for quotients by any linearly reductive group, and to Adeel Khan, Timo Richarz, Matthias Wendt and Xinwen Zhu for helpful conversations\r\nabout the results. I would moreover like to thank the referee for the very useful comments.","corr_author":"1","arxiv":1,"intvolume":"      2026"},{"citation":{"ama":"Löwit J. Equivariant K-theory, affine Grassmannian and perfection. <i>Documenta Mathematica</i>. 2026. doi:<a href=\"https://doi.org/10.4171/dm/1064\">10.4171/dm/1064</a>","chicago":"Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.” <i>Documenta Mathematica</i>. EMS Press, 2026. <a href=\"https://doi.org/10.4171/dm/1064\">https://doi.org/10.4171/dm/1064</a>.","apa":"Löwit, J. (2026). Equivariant K-theory, affine Grassmannian and perfection. <i>Documenta Mathematica</i>. EMS Press. <a href=\"https://doi.org/10.4171/dm/1064\">https://doi.org/10.4171/dm/1064</a>","short":"J. Löwit, Documenta Mathematica (2026).","ieee":"J. Löwit, “Equivariant K-theory, affine Grassmannian and perfection,” <i>Documenta Mathematica</i>. EMS Press, 2026.","mla":"Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.” <i>Documenta Mathematica</i>, EMS Press, 2026, doi:<a href=\"https://doi.org/10.4171/dm/1064\">10.4171/dm/1064</a>.","ista":"Löwit J. 2026. Equivariant K-theory, affine Grassmannian and perfection. Documenta Mathematica."},"publication_identifier":{"issn":["1431-0635"],"eissn":["1431-0643"]},"date_updated":"2026-08-26T06:53:54Z","_id":"22693","year":"2026","mathsc":["19E08","19L47","20G44","14G17","19D55","14F43","14L30","14D24","14M25"],"title":"Equivariant K-theory, affine Grassmannian and perfection","publisher":"EMS Press","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"22694"}]},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"ddc":["500"],"date_created":"2026-08-12T13:29:17Z","type":"journal_article","publication":"Documenta Mathematica","keyword":["equivariant algebraic K-theory","perfection in positive characteristic","affine Grassmannian","affine Schubert varieties","Dennis trace map","equivariant Hochschild homology","fixed-point schemes","toric varieties"],"abstract":[{"lang":"eng","text":"We study torus-equivariant algebraic K-theory of affine Schubert varieties in the perfect affine Grassmannians over Fp. We further compare it to the torus-equivariant Hochschild homology of perfect complexes, which has a geometric description in terms of global functions on certain fixed-point schemes. We prove that Fp-linearly, this comparison is an isomorphism. Our approach is quite constructive, resulting in new computations of these K-theory rings. We establish various structural results for equivariant perfect algebraic K-theory on the way; we believe these are of independent interest."}],"publication_status":"epub_ahead","article_type":"original","researchdata_availability":"no","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","language":[{"iso":"eng"}],"day":"26","main_file_link":[{"url":"https://doi.org/10.4171/DM/1064","open_access":"1"}],"has_accepted_license":"1","OA_place":"publisher","das_tickbox":"0","doi":"10.4171/dm/1064","PlanS_conform":"1","month":"03","supplementarymaterial":"no","acknowledgement":"I would like to thank the following people for fruitful discussions,\r\nhelpful sanity checks or comments on previous drafts: Roman Bezrukavnikov, Jens Niklas Eberhardt, Mischa Elkner, Tamás Hausel, Andres Fernandez Herrero, Adeel Khan,\r\nBernhard Köck, Andrei Konovalov, Quoc Ho, Mirko Mauri, Matthew Morrow, Charanya\r\nRavi, Kamil Rychlewicz, Shyiu Shen, Vladimir Sosnilo, Georg Tamme, Xinwen Zhu. I\r\nwould further like to thank Marc Hoyois and the anonymous referee for spotting an error\r\nin a previous version.\r\nThis work was done during author’s PhD at the Institute of Science and Technology Austria (ISTA). It was funded by a DOC Fellowship of the Austrian Academy\r\nof Sciences and by the Austrian Science Fund (FWF) 10.55776/P35847. For open access\r\npurposes, the author has applied a CC BY public copyright license to any author-accepted\r\nmanuscript version arising from this submission.","corr_author":"1","author":[{"id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0","first_name":"Jakub","full_name":"Löwit, Jakub","last_name":"Löwit"}],"arxiv":1,"date_published":"2026-03-26T00:00:00Z","project":[{"name":"Geometry of the tip of the global nilpotent cone","_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3","grant_number":"P35847"}],"external_id":{"arxiv":["2409.18925"]},"OA_type":"hybrid","oa":1,"status":"public","quality_controlled":"1","department":[{"_id":"GradSch"},{"_id":"TaHa"}],"oa_version":"Published Version"},{"intvolume":"       392","author":[{"id":"b4eb62ef-ac72-11ed-9503-ed3b4d66c083","first_name":"Benjamin L","orcid":"0000-0002-3461-5391","full_name":"Springstein, Benjamin L","last_name":"Springstein"},{"id":"305ab18b-dc7d-11ea-9b2f-b58195228ea2","first_name":"Manjunath","orcid":"0000-0003-2311-2112","full_name":"Javoor, Manjunath","last_name":"Javoor"},{"first_name":"Daniela","last_name":"Megrian","full_name":"Megrian, Daniela"},{"id":"ffab949d-133f-11ed-8f02-94de21ace503","first_name":"Roman","last_name":"Hajdu","full_name":"Hajdu, Roman"},{"first_name":"Dustin M.","last_name":"Hanke","full_name":"Hanke, Dustin M."},{"id":"45FD126C-F248-11E8-B48F-1D18A9856A87","first_name":"Bettina","last_name":"Zens","full_name":"Zens, Bettina","orcid":"0000-0002-9561-1239"},{"first_name":"Gregor L.","last_name":"Weiss","full_name":"Weiss, Gregor L."},{"id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian Km","orcid":"0000-0003-4790-8078","full_name":"Schur, Florian Km","last_name":"Schur"},{"last_name":"Loose","full_name":"Loose, Martin","orcid":"0000-0001-7309-9724","first_name":"Martin","id":"462D4284-F248-11E8-B48F-1D18A9856A87"}],"acknowledgement":"We thank all members of the Loose lab at ISTA for helpful discussions; M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University) for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work was funded by the European Union’s Horizon 2020 research and innovation program (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques et Letitia Lopez-Loreta Foundation (G.L.W.).","corr_author":"1","department":[{"_id":"MaLo"},{"_id":"FlSc"},{"_id":"GradSch"},{"_id":"EM-Fac"}],"oa_version":"None","quality_controlled":"1","status":"public","OA_type":"closed access","external_id":{"pmid":["41990175"]},"project":[{"grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"},{"name":"A molecular atlas of Actin filament IDentities in the cell motility machinery","_id":"bd980d18-d553-11ed-ba76-ceaa645c97eb","grant_number":"101076260"}],"date_published":"2026-04-16T00:00:00Z","issue":"6795","day":"16","article_processing_charge":"No","language":[{"iso":"eng"}],"scopus_import":"1","month":"04","doi":"10.1126/science.aea6343","type":"journal_article","date_created":"2026-04-26T22:01:46Z","related_material":{"record":[{"id":"22744","relation":"dissertation_contains","status":"for_moderation"}]},"publication_status":"published","article_type":"original","article_number":"eaea6343","abstract":[{"lang":"eng","text":"Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal system named CorMR with a function in cell shape control rather than DNA segregation. Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed that CorM formed dynamically unstable, antiparallel double-stranded filaments that were recruited to the membrane by CorR through an amphipathic helix conserved in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which excluded them from the poles and division plane. Comparative genomics indicated that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity, highlighting the evolutionary plasticity of cytoskeletal systems in bacteria."}],"volume":392,"publication":"Science","acknowledged_ssus":[{"_id":"Bio"},{"_id":"ScienComp"},{"_id":"EM-Fac"},{"_id":"LifeSc"}],"_id":"21762","date_updated":"2026-08-26T09:09:05Z","pmid":1,"publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"citation":{"ieee":"B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392, no. 6795. AAAS, 2026.","short":"B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L. Weiss, F.K. Schur, M. Loose, Science 392 (2026).","mla":"Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392, no. 6795, eaea6343, AAAS, 2026, doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>.","ista":"Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL, Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. Science. 392(6795), eaea6343.","chicago":"Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu, Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose. “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>. AAAS, 2026. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>.","apa":"Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens, B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.aea6343\">https://doi.org/10.1126/science.aea6343</a>","ama":"Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795). doi:<a href=\"https://doi.org/10.1126/science.aea6343\">10.1126/science.aea6343</a>"},"publisher":"AAAS","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ec_funded":1,"title":"Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape","year":"2026"}]