---
OA_place: repository
OA_type: green
_id: '22718'
abstract:
- lang: eng
  text: Both Newtonian and non-Newtonian fluids may exhibit complex slip behaviour
    at the boundary. We examine a broad class of slip boundary conditions that generalises
    the commonly used Navier slip, perfect slip, stick-slip and Tresca friction boundary
    conditions. In particular, set-valued, nonmonotone, noncoercive and dynamic relations
    may occur. For a unifying framework of such relations, we present a fully discrete
    numerical scheme for the time-dependent Navier–Stokes equations subject to impermeability
    and general slip-type boundary conditions on polyhedral domains. Based on compactness
    arguments, we prove convergence of subsequences, finally ensuring the existence
    of a weak solution. The numerical scheme uses a general inf-sup stable pair of
    finite element spaces for the velocity and pressure, a regularisation approach
    for the implicit slip boundary condition and, most importantly, a general Nitsche
    method to impose the impermeability and a backward Euler time stepping. One of
    the key tools in the convergence proof is an inhomogeneous Korn inequality that
    includes a normal trace term.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Pablo Alexei
  full_name: Gazca-Orozco, Pablo Alexei
  last_name: Gazca-Orozco
- first_name: Franz
  full_name: Gmeineder, Franz
  last_name: Gmeineder
- first_name: Erika
  full_name: Maringová, Erika
  id: dbabca31-66eb-11eb-963a-fb9c22c880b4
  last_name: Maringová
- first_name: Tabea
  full_name: Tscherpel, Tabea
  last_name: Tscherpel
citation:
  ama: Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. A Nitsche method for
    incompressible fluids with general dynamic boundary conditions. <i>Mathematical
    Models and Methods in Applied Sciences</i>. 2026. doi:<a href="https://doi.org/10.1142/S0218202526500508">10.1142/S0218202526500508</a>
  apa: Gazca-Orozco, P. A., Gmeineder, F., Maringová, E., &#38; Tscherpel, T. (2026).
    A Nitsche method for incompressible fluids with general dynamic boundary conditions.
    <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing.
    <a href="https://doi.org/10.1142/S0218202526500508">https://doi.org/10.1142/S0218202526500508</a>
  chicago: Gazca-Orozco, Pablo Alexei, Franz Gmeineder, Erika Maringová, and Tabea
    Tscherpel. “A Nitsche Method for Incompressible Fluids with General Dynamic Boundary
    Conditions.” <i>Mathematical Models and Methods in Applied Sciences</i>. World
    Scientific Publishing, 2026. <a href="https://doi.org/10.1142/S0218202526500508">https://doi.org/10.1142/S0218202526500508</a>.
  ieee: P. A. Gazca-Orozco, F. Gmeineder, E. Maringová, and T. Tscherpel, “A Nitsche
    method for incompressible fluids with general dynamic boundary conditions,” <i>Mathematical
    Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026.
  ista: Gazca-Orozco PA, Gmeineder F, Maringová E, Tscherpel T. 2026. A Nitsche method
    for incompressible fluids with general dynamic boundary conditions. Mathematical
    Models and Methods in Applied Sciences.
  mla: Gazca-Orozco, Pablo Alexei, et al. “A Nitsche Method for Incompressible Fluids
    with General Dynamic Boundary Conditions.” <i>Mathematical Models and Methods
    in Applied Sciences</i>, World Scientific Publishing, 2026, doi:<a href="https://doi.org/10.1142/S0218202526500508">10.1142/S0218202526500508</a>.
  short: P.A. Gazca-Orozco, F. Gmeineder, E. Maringová, T. Tscherpel, Mathematical
    Models and Methods in Applied Sciences (2026).
date_created: 2026-08-16T22:01:44Z
date_published: 2026-08-04T00:00:00Z
date_updated: 2026-08-18T07:51:59Z
day: '04'
department:
- _id: JuFi
doi: 10.1142/S0218202526500508
external_id:
  arxiv:
  - '2502.09550'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2502.09550
mathsc:
- 65N30
- 76D07
- 76M10
month: '08'
oa: 1
oa_version: Preprint
publication: Mathematical Models and Methods in Applied Sciences
publication_identifier:
  eissn:
  - 1793-6314
  issn:
  - 0218-2025
publication_status: epub_ahead
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: A Nitsche method for incompressible fluids with general dynamic boundary conditions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22734'
abstract:
- lang: eng
  text: Silver selenide (Ag2Se) is a promising near-room-temperature thermoelectric
    material, but its narrow stoichiometric window and β–α phase transition complicate
    reproducible microstructure control. Here, we present a mismatch-assisted microstructure
    engineering strategy in which Ag2Se particles are treated with polyanionic ZnSe
    complexes and consolidated through the β–α transition to introduce ZnSe nanoprecipitates,
    Ag2Se/ZnSe interfaces, and local strain fields. The crystallographic mismatch
    between ZnSe and Ag2Se, together with the Zn2+/Ag+ size difference, amplifies
    phase-transition-induced deformation and promotes high-density dislocations with
    periodic strain modulations. This defect architecture suppresses grain coarsening,
    removes excess Ag, limits Ag-interstitial formation, and reduces lattice thermal
    conductivity through lattice softening and multiscale phonon scattering. Ag2Se–4%ZnSe
    nanocomposites achieve a peak zTmax of 1.13 at 369 K and a zTavg of 1.08 from
    300 to 380 K, demonstrating mismatch-driven defect engineering through the β–α
    phase transition as a route for optimizing Ag2Se-based thermoelectrics.
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
- _id: NanoFab
- _id: MassSpec
acknowledgement: 'Open access funding provided by Institute of Science and Technology
  Austria. M.I. acknowledges financial support from ISTA and the Werner Siemens Foundation.
  The Scientific Service Units (SSU) of ISTA supported this work through resources
  provided by the Electron Microscopy Facility (EMF), the Lab Support Facility (LSF),
  the Nanofabrication Facility (NNF), and the Mass Spectrometry Facility. Y.L. acknowledges
  funding from the National Natural Science Foundation of China (NSFC) (grant no.
  22209034) and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239).
  M.H. acknowledges funding from Australian Research Council (FT230100316), and the
  high-performance computing resources provided by National Computational Infrastructure
  (it39) and Pawsey Supercomputing Centre (pawsey1075). ICN2 acknowledges funding
  from Generalitat de Catalunya 2021SGR00457. The authors thank support from the project
  AMaDE (PID2023-149158OB-C43), funded by MCIN/AEI/10.13039/501100011033/ and by the
  “ERDF Away of making Europe”, by the “European Union”. ICN2 is supported by the
  Severo Ochoa program from Spanish MCIN/AEI (grant no.: CEX2021-001214-S) and is
  funded by the CERCA Programme/Generalitat de Catalunya. Authors acknowledge the
  use of instrumentation as well as the technical advice provided by the Joint Electron
  Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206
  (METCAM-FIB) funded by the European Union through the European Regional Development
  Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat
  de Catalunya. ICN2 is founding member of e-DREAM. (91)'
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Yu
  full_name: Liu, Yu
  id: 2A70014E-F248-11E8-B48F-1D18A9856A87
  last_name: Liu
  orcid: 0000-0001-7313-6740
- first_name: Tobias
  full_name: Kleinhanns, Tobias
  id: 8BD9DE16-AB3C-11E9-9C8C-2A03E6697425
  last_name: Kleinhanns
  orcid: 0000-0003-1537-7436
- first_name: Maria Chiara
  full_name: Spadaro, Maria Chiara
  last_name: Spadaro
- first_name: Aziz
  full_name: Genç, Aziz
  last_name: Genç
- first_name: Sharona
  full_name: Horta, Sharona
  id: 03a7e858-01b1-11ec-8b71-99ae6c4a05bc
  last_name: Horta
- first_name: Navita
  full_name: Navita, Navita
  id: 6ebe278d-ba0b-11ee-8184-f34cdc671de4
  last_name: Navita
  orcid: 0000-0001-7408-8197
- first_name: Tommaso
  full_name: Costanzo, Tommaso
  id: D93824F4-D9BA-11E9-BB12-F207E6697425
  last_name: Costanzo
  orcid: 0000-0001-9732-3815
- first_name: Ewelina
  full_name: Dutkiewicz, Ewelina
  id: 0601cc46-c082-11ec-9b07-bb29641d1de9
  last_name: Dutkiewicz
- first_name: Jordi
  full_name: Arbiol, Jordi
  last_name: Arbiol
- first_name: Min
  full_name: Hong, Min
  last_name: Hong
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
citation:
  ama: Liu Y, Kleinhanns T, Spadaro MC, et al. Exploiting mismatch strain and the
    β–α phase transition for microstructural engineering in thermoelectric Ag2Se.
    <i>ACS Energy Letters</i>. 2026;11(8):5752-5762. doi:<a href="https://doi.org/10.1021/acsenergylett.6c01499">10.1021/acsenergylett.6c01499</a>
  apa: Liu, Y., Kleinhanns, T., Spadaro, M. C., Genç, A., Horta, S., Jakhar, N., …
    Ibáñez, M. (2026). Exploiting mismatch strain and the β–α phase transition for
    microstructural engineering in thermoelectric Ag2Se. <i>ACS Energy Letters</i>.
    American Chemical Society. <a href="https://doi.org/10.1021/acsenergylett.6c01499">https://doi.org/10.1021/acsenergylett.6c01499</a>
  chicago: Liu, Yu, Tobias Kleinhanns, Maria Chiara Spadaro, Aziz Genç, Sharona Horta,
    Navita Jakhar, Tommaso Costanzo, et al. “Exploiting Mismatch Strain and the β–α
    Phase Transition for Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS
    Energy Letters</i>. American Chemical Society, 2026. <a href="https://doi.org/10.1021/acsenergylett.6c01499">https://doi.org/10.1021/acsenergylett.6c01499</a>.
  ieee: Y. Liu <i>et al.</i>, “Exploiting mismatch strain and the β–α phase transition
    for microstructural engineering in thermoelectric Ag2Se,” <i>ACS Energy Letters</i>,
    vol. 11, no. 8. American Chemical Society, pp. 5752–5762, 2026.
  ista: Liu Y, Kleinhanns T, Spadaro MC, Genç A, Horta S, Jakhar N, Costanzo T, Dutkiewicz
    E, Arbiol J, Hong M, Ibáñez M. 2026. Exploiting mismatch strain and the β–α phase
    transition for microstructural engineering in thermoelectric Ag2Se. ACS Energy
    Letters. 11(8), 5752–5762.
  mla: Liu, Yu, et al. “Exploiting Mismatch Strain and the β–α Phase Transition for
    Microstructural Engineering in Thermoelectric Ag2Se.” <i>ACS Energy Letters</i>,
    vol. 11, no. 8, American Chemical Society, 2026, pp. 5752–62, doi:<a href="https://doi.org/10.1021/acsenergylett.6c01499">10.1021/acsenergylett.6c01499</a>.
  short: Y. Liu, T. Kleinhanns, M.C. Spadaro, A. Genç, S. Horta, N. Jakhar, T. Costanzo,
    E. Dutkiewicz, J. Arbiol, M. Hong, M. Ibáñez, ACS Energy Letters 11 (2026) 5752–5762.
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-18T11:34:03Z
date_published: 2026-08-14T00:00:00Z
date_updated: 2026-08-19T05:53:33Z
day: '14'
ddc:
- '540'
department:
- _id: MassSpec
- _id: MaIb
- _id: GradSch
- _id: EM-Fac
doi: 10.1021/acsenergylett.6c01499
file:
- access_level: open_access
  checksum: 4d75c5a79d112c845c9eecba8838db38
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-19T05:52:41Z
  date_updated: 2026-08-19T05:52:41Z
  file_id: '22736'
  file_name: 2026_ACSEnergyLetters_Liu.pdf
  file_size: 6806815
  relation: main_file
  success: 1
file_date_updated: 2026-08-19T05:52:41Z
has_accepted_license: '1'
intvolume: '        11'
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 5752-5762
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: ACS Energy Letters
publication_identifier:
  eissn:
  - 2380-8195
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Exploiting mismatch strain and the β–α phase transition for microstructural
  engineering in thermoelectric Ag2Se
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22715'
abstract:
- lang: eng
  text: 'Grazing-incidence small-angle scattering (GISAS) is a relatively young technique
    with important applications in thin-film technology and untapped potential when
    it comes to 2D analysis on an absolute intensity scale. Approaching standardization
    and reference methods early is foundational for reproducibility and comparability
    across laboratories and reduction of systematic error sources. It underpins trust
    in data obtained and accelerates innovation by ensuring that scientists work from
    a common methodological baseline. Accordingly, obtaining reproducible results
    from different GISAS instruments requires an agreement on how measurements are
    performed, instruments calibrated and terms defined. To pave the way for standardization
    and reference methods, we surveyed GISAS practitioners on what comes before an
    experiment: hardware, software, sample alignment and instrument calibration. Twenty-two
    questions were designed to elucidate the state of the art, which can be used for
    the development of reference methods. Our data on 27 instruments provide the basis
    for standardization. With very few exceptions, we found laboratories prepared
    to implement future reference methods, but no consensus emerges naturally for
    sample alignment and instrument calibration. We, that is the GISAS community,
    are thus in a position to embark on the journey of standardization.'
acknowledgement: "The authors thank all respondents for their participation in the\r\nquestionnaire.
  We plan to make further use of the wealth of\r\nthe dataset going forward. We thank
  Xenocs for sharing\r\napproximate data on GISAXS equipment sales and Adrian\r\nRennie
  for helpful discussions. Open access funding enabled\r\nand organized by Projekt
  DEAL."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Anja F.
  full_name: Hörmann, Anja F.
  last_name: Hörmann
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Ingo
  full_name: Breßler, Ingo
  last_name: Breßler
- first_name: Sumea
  full_name: Klokic, Sumea
  last_name: Klokic
- first_name: Melika
  full_name: Moradi, Melika
  last_name: Moradi
- first_name: Eduardo
  full_name: Solano, Eduardo
  last_name: Solano
- first_name: Annika
  full_name: Stellhorn, Annika
  last_name: Stellhorn
- first_name: Brian R.
  full_name: Pauw, Brian R.
  last_name: Pauw
citation:
  ama: 'Hörmann AF, Balazs D, Breßler I, et al. Grazing-incidence scattering surveyed:
    Towards reference methods for alignment and calibration. <i>Journal of Applied
    Crystallography</i>. 2026;59(4):1247-1253. doi:<a href="https://doi.org/10.1107/S1600576726005741">10.1107/S1600576726005741</a>'
  apa: 'Hörmann, A. F., Balazs, D., Breßler, I., Klokic, S., Moradi, M., Solano, E.,
    … Pauw, B. R. (2026). Grazing-incidence scattering surveyed: Towards reference
    methods for alignment and calibration. <i>Journal of Applied Crystallography</i>.
    International Union of Crystallography. <a href="https://doi.org/10.1107/S1600576726005741">https://doi.org/10.1107/S1600576726005741</a>'
  chicago: 'Hörmann, Anja F., Daniel Balazs, Ingo Breßler, Sumea Klokic, Melika Moradi,
    Eduardo Solano, Annika Stellhorn, and Brian R. Pauw. “Grazing-Incidence Scattering
    Surveyed: Towards Reference Methods for Alignment and Calibration.” <i>Journal
    of Applied Crystallography</i>. International Union of Crystallography, 2026.
    <a href="https://doi.org/10.1107/S1600576726005741">https://doi.org/10.1107/S1600576726005741</a>.'
  ieee: 'A. F. Hörmann <i>et al.</i>, “Grazing-incidence scattering surveyed: Towards
    reference methods for alignment and calibration,” <i>Journal of Applied Crystallography</i>,
    vol. 59, no. 4. International Union of Crystallography, pp. 1247–1253, 2026.'
  ista: 'Hörmann AF, Balazs D, Breßler I, Klokic S, Moradi M, Solano E, Stellhorn
    A, Pauw BR. 2026. Grazing-incidence scattering surveyed: Towards reference methods
    for alignment and calibration. Journal of Applied Crystallography. 59(4), 1247–1253.'
  mla: 'Hörmann, Anja F., et al. “Grazing-Incidence Scattering Surveyed: Towards Reference
    Methods for Alignment and Calibration.” <i>Journal of Applied Crystallography</i>,
    vol. 59, no. 4, International Union of Crystallography, 2026, pp. 1247–53, doi:<a
    href="https://doi.org/10.1107/S1600576726005741">10.1107/S1600576726005741</a>.'
  short: A.F. Hörmann, D. Balazs, I. Breßler, S. Klokic, M. Moradi, E. Solano, A.
    Stellhorn, B.R. Pauw, Journal of Applied Crystallography 59 (2026) 1247–1253.
das_tickbox: '1'
dataavailabilitystatement: "The response data are available at https://doi.org/10.5281/\r\nzenodo.18712813.
  The literate programming source of this\r\nwork is available at https://doi.org/10.5281/zenodo.18713631."
date_created: 2026-08-16T22:01:43Z
date_published: 2026-08-01T00:00:00Z
date_updated: 2026-08-20T06:14:07Z
day: '01'
ddc:
- '540'
department:
- _id: LifeSc
doi: 10.1107/S1600576726005741
file:
- access_level: open_access
  checksum: 8dbad0ab078338021e2cfe722211df7b
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-20T05:51:36Z
  date_updated: 2026-08-20T05:51:36Z
  file_id: '22739'
  file_name: 2026_JourAppliedCrystallography_Hoermann.pdf
  file_size: 6692218
  relation: main_file
  success: 1
file_date_updated: 2026-08-20T05:51:36Z
has_accepted_license: '1'
intvolume: '        59'
issue: '4'
keyword:
- grazing incidence
- reference methods
- calibration
- standardization
- community
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 1247-1253
publication: Journal of Applied Crystallography
publication_identifier:
  eissn:
  - 1600-5767
  issn:
  - 0021-8898
publication_status: published
publisher: International Union of Crystallography
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'Grazing-incidence scattering surveyed: Towards reference methods for alignment
  and calibration'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 59
year: '2026'
...
---
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '22716'
abstract:
- lang: eng
  text: We give an algorithm that, with high probability, maintains a (1-ε)-approximate
    s-t maximum flow in undirected, uncapacitated n-vertex graphs undergoing m edge
    insertions in Õ(m+ n F^*/ε) total update time, where F^{*} is the maximum flow
    on the final graph. This is the first algorithm to achieve polylogarithmic amortized
    update time for dense graphs (m = Ω(n²)), and more generally, for graphs where
    F^* = Õ(m/n). At the heart of our incremental algorithm is the residual graph
    sparsification technique of Karger and Levine [SICOMP '15], originally designed
    for computing exact maximum flows in the static setting. Our main contributions
    are (i) showing how to maintain such sparsifiers for approximate maximum flows
    in the incremental setting and (ii) generalizing the cut sparsification framework
    of Fung et al. [SICOMP '19] from undirected graphs to balanced directed graphs.
acknowledgement: "M. Henzinger: This project has received funding from the European
  Research Council (ERC) under the European Union’s\r\nHorizon 2020 research and innovation
  programme (MoDynStruct, No. 101019564)   and the Austrian Science Fund\r\n(FWF)
  grant DOI 10.55776/Z422, grant DOI 10.55776/I5982, and grant DOI 10.55776/P33775
  with additional funding from the\r\nnetidee SCIENCE Stiftung, 2020–2024. Views and
  opinions expressed are those of the author(s) only and do not necessarily\r\nreflect
  those of the European Union or the European Research Council Executive Agency. Neither
  the European Union nor\r\nthe granting authority can be held responsible for them"
article_number: '31'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Gramoz
  full_name: Goranci, Gramoz
  last_name: Goranci
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Harald
  full_name: Räcke, Harald
  last_name: Räcke
- first_name: A. R.
  full_name: Sricharan, A. R.
  last_name: Sricharan
citation:
  ama: Goranci G, Henzinger M, Räcke H, Sricharan AR. Incremental approximate maximum
    flow via residual graph sparsification. <i>ACM Transactions on Algorithms</i>.
    2026;22(3). doi:<a href="https://doi.org/10.1145/3816252">10.1145/3816252</a>
  apa: Goranci, G., Henzinger, M., Räcke, H., &#38; Sricharan, A. R. (2026). Incremental
    approximate maximum flow via residual graph sparsification. <i>ACM Transactions
    on Algorithms</i>. ACM. <a href="https://doi.org/10.1145/3816252">https://doi.org/10.1145/3816252</a>
  chicago: Goranci, Gramoz, Monika Henzinger, Harald Räcke, and A. R. Sricharan. “Incremental
    Approximate Maximum Flow via Residual Graph Sparsification.” <i>ACM Transactions
    on Algorithms</i>. ACM, 2026. <a href="https://doi.org/10.1145/3816252">https://doi.org/10.1145/3816252</a>.
  ieee: G. Goranci, M. Henzinger, H. Räcke, and A. R. Sricharan, “Incremental approximate
    maximum flow via residual graph sparsification,” <i>ACM Transactions on Algorithms</i>,
    vol. 22, no. 3. ACM, 2026.
  ista: Goranci G, Henzinger M, Räcke H, Sricharan AR. 2026. Incremental approximate
    maximum flow via residual graph sparsification. ACM Transactions on Algorithms.
    22(3), 31.
  mla: Goranci, Gramoz, et al. “Incremental Approximate Maximum Flow via Residual
    Graph Sparsification.” <i>ACM Transactions on Algorithms</i>, vol. 22, no. 3,
    31, ACM, 2026, doi:<a href="https://doi.org/10.1145/3816252">10.1145/3816252</a>.
  short: G. Goranci, M. Henzinger, H. Räcke, A.R. Sricharan, ACM Transactions on Algorithms
    22 (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-16T22:01:43Z
date_published: 2026-07-06T00:00:00Z
date_updated: 2026-08-20T06:28:01Z
day: '06'
ddc:
- '000'
department:
- _id: MoHe
doi: 10.1145/3816252
ec_funded: 1
external_id:
  arxiv:
  - '2502.09105'
file:
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  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-20T06:19:51Z
  date_updated: 2026-08-20T06:19:51Z
  file_id: '22740'
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  success: 1
file_date_updated: 2026-08-20T06:19:51Z
has_accepted_license: '1'
intvolume: '        22'
issue: '3'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
  grant_number: Z00422
  name: Efficient algorithms
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
  grant_number: I05982
  name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
  grant_number: P33775
  name: Fast Algorithms for a Reactive Network Layer
publication: ACM Transactions on Algorithms
publication_identifier:
  eissn:
  - 1549-6333
  issn:
  - 1549-6325
publication_status: published
publisher: ACM
quality_controlled: '1'
related_material:
  record:
  - id: '21280'
    relation: earlier_version
    status: public
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Incremental approximate maximum flow via residual graph sparsification
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 22
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '22714'
abstract:
- lang: eng
  text: Radial glial progenitors (RGPs) generate all projection neurons (PNs) in the
    cerebral cortex through incompletely understood processes. We combined Mosaic
    Analysis with Double Markers at embryonic stages (E)12.5 and E13.5 with early
    postnatal callosal tracing to dissect RGP lineage progression. We find that multipotent
    RGPs generate all extra-telencephalic (ET) and intra-telencephalic (IT) PNs via
    parallel sublineages that emerge simultaneously at neurogenesis onset. ET-PN production
    progresses exclusively via small, self-consuming lineages; IT-PN lineages feature
    RGPs generating large translaminar outputs. The early emergence of IT-PN–fated
    RGPs, coinciding with a switch to direct neurogenesis, contributes to the stereotyped
    population-level progression of the multipotent lineage. We also identify POU3F
    transcription factors as candidate regulators of IT-PN fate via noncanonical mitotic
    chromatin binding. The results support a model whereby IT- and ET-PNs arise from
    an early bifurcation and parallel specification within the multipotent RGP lineage.
acknowledgement: 'We thank M. caouyette for the plasmid construction for Pou3f1overexpression;
  d. Pinto-Benito for valuable assistance with shRnA validation in n2A cells andqPcR
  experiments; c. Varela-Martínez for help with the code for graphical analysis; allmembers
  from the nieto’s lab for comment on the manuscript, specially to F. Martín for theinsightful
  discussions; J. c. Oliveros and J. A. García from the computational service of the
  cnBfor help with the analysis of RnAseq dataset; c. O. Sorzano for help with statistical
  analysis; andA. Oña and the service of Advance Optical Microscopy of the cnB for
  technical advice.Funding: i.V.-M. holds a fellowship funded by MciciU (PRe-2018-083376)
  and 2023 eMBOscientific exchange grant 10214. the work was funded by grants to M.n.
  (Pid2020-112831GB- i00 and Pid2023-146322nB- i00 by Mcin/Aei/10.13039/501100011033
  and by“eRdF A way of making europe”).'
article_processing_charge: Yes
article_type: original
author:
- first_name: Irene
  full_name: Varela Martínez, Irene
  id: a69b5985-8829-11f0-8fc2-d0af58f64471
  last_name: Varela Martínez
- first_name: Ana
  full_name: Villalba Requena, Ana
  id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
  last_name: Villalba Requena
  orcid: 0000-0002-5615-5277
- first_name: Jorge
  full_name: García-Marqués, Jorge
  last_name: García-Marqués
- first_name: Alfonso
  full_name: Aguilera, Alfonso
  last_name: Aguilera
- first_name: Diogo S.
  full_name: Castro, Diogo S.
  last_name: Castro
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Marta
  full_name: Nieto, Marta
  last_name: Nieto
citation:
  ama: Varela Martínez I, Villalba Requena A, García-Marqués J, et al. Early fate
    diversification of radial glial progenitors during corticogenesis. <i>Science
    Advances</i>. 2026;12(32):eadw5487. doi:<a href="https://doi.org/10.1126/sciadv.adw5487">10.1126/sciadv.adw5487</a>
  apa: Varela Martínez, I., Villalba Requena, A., García-Marqués, J., Aguilera, A.,
    Castro, D. S., Hippenmeyer, S., &#38; Nieto, M. (2026). Early fate diversification
    of radial glial progenitors during corticogenesis. <i>Science Advances</i>. AAAS.
    <a href="https://doi.org/10.1126/sciadv.adw5487">https://doi.org/10.1126/sciadv.adw5487</a>
  chicago: Varela Martínez, Irene, Ana Villalba Requena, Jorge García-Marqués, Alfonso
    Aguilera, Diogo S. Castro, Simon Hippenmeyer, and Marta Nieto. “Early Fate Diversification
    of Radial Glial Progenitors during Corticogenesis.” <i>Science Advances</i>. AAAS,
    2026. <a href="https://doi.org/10.1126/sciadv.adw5487">https://doi.org/10.1126/sciadv.adw5487</a>.
  ieee: I. Varela Martínez <i>et al.</i>, “Early fate diversification of radial glial
    progenitors during corticogenesis,” <i>Science Advances</i>, vol. 12, no. 32.
    AAAS, p. eadw5487, 2026.
  ista: Varela Martínez I, Villalba Requena A, García-Marqués J, Aguilera A, Castro
    DS, Hippenmeyer S, Nieto M. 2026. Early fate diversification of radial glial progenitors
    during corticogenesis. Science Advances. 12(32), eadw5487.
  mla: Varela Martínez, Irene, et al. “Early Fate Diversification of Radial Glial
    Progenitors during Corticogenesis.” <i>Science Advances</i>, vol. 12, no. 32,
    AAAS, 2026, p. eadw5487, doi:<a href="https://doi.org/10.1126/sciadv.adw5487">10.1126/sciadv.adw5487</a>.
  short: I. Varela Martínez, A. Villalba Requena, J. García-Marqués, A. Aguilera,
    D.S. Castro, S. Hippenmeyer, M. Nieto, Science Advances 12 (2026) eadw5487.
das_tickbox: '1'
dataavailabilitystatement: 'All data and code needed to evaluate and reproduce the
  results in the paper are present in the paper and/or the Supplementary Materials.
  Source data underlying all figures (including the clonal atlas) are provided in
  the Supplementary Materials. RnA-seq analysis code has been deposited in Zenodo
  (dOi: 10.5281/zenodo.14609057). this study did not generate new materials.'
date_created: 2026-08-16T22:01:43Z
date_published: 2026-08-07T00:00:00Z
date_updated: 2026-08-20T05:45:28Z
day: '07'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1126/sciadv.adw5487
external_id:
  pmid:
  - '42555737'
file:
- access_level: open_access
  checksum: 487c3703387080e8f3c4675d67763f0e
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-20T05:39:32Z
  date_updated: 2026-08-20T05:39:32Z
  file_id: '22738'
  file_name: 2026_ScienceAdv_VarelaMartinez.pdf
  file_size: 3056744
  relation: main_file
  success: 1
file_date_updated: 2026-08-20T05:39:32Z
has_accepted_license: '1'
intvolume: '        12'
issue: '32'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: eadw5487
pmid: 1
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Early fate diversification of radial glial progenitors during corticogenesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '22733'
abstract:
- lang: eng
  text: Sleep need is associated with both circuit dynamics and widespread synaptic
    plasticity, yet the specific synaptic changes underlying sleep homeostasis remain
    incompletely understood. In Drosophila, sleep loss has been shown to trigger plasticity
    of the presynaptic active zone, marked by increasing levels of the ELKS-family
    scaffold protein Bruchpilot (BRP). By titrating brp gene copy number, we previously
    established a presynapse-specific, dosage-dependent paradigm that modulates sleep
    pressure. Here, to elucidate the molecular landscape of this plasticity, we performed
    synapse-enriched integrated-omics. Proteomic and bioinformatic analyses revealed
    changes in immune and stress response pathways and local translation control.
    Strikingly, phospho-proteomic analysis uncovered a global shift toward hypophosphorylation,
    particularly in presynaptic proteins, indicating a reprogramming of the phosphorylation–dephosphorylation
    balance. This presynaptic hypophosphorylation is likely contributed by reduced
    activity of Protein Kinase A (PKA) and enhanced substrate affinity of Protein
    Phosphatase 1 (PP1) mediated by its regulatory subunit Spinophilin (Spn). Manipulating
    either PKA or PP1 activity was sufficient to suppress BRP-modulated sleep phenotypes.
    We propose that presynaptic hypophosphorylation constitutes a molecular signature
    of local synaptic remodeling that adaptively tunes sleep need via reversible posttranslational
    modification, a mechanism likely conserved across species.
article_number: e2524065123
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Chengji
  full_name: Piao, Chengji
  last_name: Piao
- first_name: Ewelina
  full_name: Dutkiewicz, Ewelina
  id: 0601cc46-c082-11ec-9b07-bb29641d1de9
  last_name: Dutkiewicz
- first_name: Laxmikanth
  full_name: Kollipara, Laxmikanth
  last_name: Kollipara
- first_name: Albert
  full_name: Sickmann, Albert
  last_name: Sickmann
- first_name: Sheng
  full_name: Huang, Sheng
  last_name: Huang
- first_name: Stephan J.
  full_name: Sigrist, Stephan J.
  last_name: Sigrist
citation:
  ama: Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. Active
    zone plasticity couples sleep need to presynaptic hypophosphorylation. <i>Proceedings
    of the National Academy of Sciences</i>. 2026;123(24). doi:<a href="https://doi.org/10.1073/pnas.2524065123">10.1073/pnas.2524065123</a>
  apa: Piao, C., Dutkiewicz, E., Kollipara, L., Sickmann, A., Huang, S., &#38; Sigrist,
    S. J. (2026). Active zone plasticity couples sleep need to presynaptic hypophosphorylation.
    <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences.
    <a href="https://doi.org/10.1073/pnas.2524065123">https://doi.org/10.1073/pnas.2524065123</a>
  chicago: Piao, Chengji, Ewelina Dutkiewicz, Laxmikanth Kollipara, Albert Sickmann,
    Sheng Huang, and Stephan J. Sigrist. “Active Zone Plasticity Couples Sleep Need
    to Presynaptic Hypophosphorylation.” <i>Proceedings of the National Academy of
    Sciences</i>. National Academy of Sciences, 2026. <a href="https://doi.org/10.1073/pnas.2524065123">https://doi.org/10.1073/pnas.2524065123</a>.
  ieee: C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, and S. J. Sigrist,
    “Active zone plasticity couples sleep need to presynaptic hypophosphorylation,”
    <i>Proceedings of the National Academy of Sciences</i>, vol. 123, no. 24. National
    Academy of Sciences, 2026.
  ista: Piao C, Dutkiewicz E, Kollipara L, Sickmann A, Huang S, Sigrist SJ. 2026.
    Active zone plasticity couples sleep need to presynaptic hypophosphorylation.
    Proceedings of the National Academy of Sciences. 123(24), e2524065123.
  mla: Piao, Chengji, et al. “Active Zone Plasticity Couples Sleep Need to Presynaptic
    Hypophosphorylation.” <i>Proceedings of the National Academy of Sciences</i>,
    vol. 123, no. 24, e2524065123, National Academy of Sciences, 2026, doi:<a href="https://doi.org/10.1073/pnas.2524065123">10.1073/pnas.2524065123</a>.
  short: C. Piao, E. Dutkiewicz, L. Kollipara, A. Sickmann, S. Huang, S.J. Sigrist,
    Proceedings of the National Academy of Sciences 123 (2026).
date_created: 2026-08-18T10:46:33Z
date_published: 2026-06-16T00:00:00Z
date_updated: 2026-08-20T05:35:33Z
day: '16'
ddc:
- '570'
doi: 10.1073/pnas.2524065123
extern: '1'
external_id:
  pmid:
  - '42258713'
file:
- access_level: open_access
  checksum: 3727c5ad18c1e9c65672fbb01ac6ea04
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-20T05:34:25Z
  date_updated: 2026-08-20T05:34:25Z
  file_id: '22737'
  file_name: 2026_PNAS_Piao.pdf
  file_size: 3915000
  relation: main_file
  success: 1
file_date_updated: 2026-08-20T05:34:25Z
has_accepted_license: '1'
intvolume: '       123'
issue: '24'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  issn:
  - 0027-8424
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active zone plasticity couples sleep need to presynaptic hypophosphorylation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 123
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '22712'
abstract:
- lang: eng
  text: Ginseng (Panax ginseng) derives its renowned therapeutic properties from ginsenoside
    metabolites. However, the long cultivation cycle and susceptibility to diseases
    hinder the advancement of the ginseng industry. Here, we demonstrate that the
    embryonic protoderm of ginseng can efficiently produce ginsenosides. Single-cell
    transcriptome and mass spectrometry imaging analyses reveal that ginsenosides
    accumulate in the protoderm of ginseng embryonic callus (EC) at levels comparable
    to those in forest ginseng. Epigenetic analyses indicate that elevated histone
    acetylation and enhanced chromatin accessibility at regeneration- and ginsenoside
    metabolism-related gene loci are associated with the ginsenoside-producing capacity
    of EC. Increasing histone acetylation levels or overexpressing the regeneration-related
    WUSCHEL-RELATED HOMEOBOX11 (WOX11) gene further enhances ginsenoside production
    in EC. Our findings suggest that the protoderm of EC could serve as an in situ
    biological compartment for high-efficiency ginsenoside producion, offering a complementary
    approach to traditional ginseng cultivation.
acknowledgement: 'The authors are grateful to Professor Linfeng Li from the School
  of Life Science, Fudan University, for his assistance during the ginseng genome
  annotation. This work was supported by Key project at central government level:
  The ability establishment of sustainable use for valuable Chinese medicine resources
  (2060302-2401-08 to L.X. and J.L.), the National Natural Science Foundation of China
  (82373987 to J.L., 31701294 to L.X., 32225007 to L.X., and 32300285 to N.Z.), the
  Fundamental Research Funds for the Central public welfare research institutes (ZZ13-YQ-093,
  ZZXT202508 to J.L.), the CACMS Innovation Fund (CI2025G00-06 to J.L.), the Principle
  Investigator Program (HBMUPI202104 to Y.Z.), the Key R&D Program of Shandong Province,
  China (2024LZGC025 to L.X.), the National Key R&D Program of China (2024YFF1000700/2023YFE0101100
  to L.X.), Strategic Priority Research Program of Chinese Academy of Sciences (XDB0630000
  to L.X.), and China Postdoctoral Science Foundation (2023M733490 to N.Z.).'
article_number: '7994'
article_processing_charge: Yes
article_type: original
author:
- first_name: Juan
  full_name: Liu, Juan
  last_name: Liu
- first_name: Ning
  full_name: Zhai, Ning
  last_name: Zhai
- first_name: Shiyi
  full_name: Zhang, Shiyi
  last_name: Zhang
- first_name: Yosuke
  full_name: Tamada, Yosuke
  last_name: Tamada
- first_name: Tonghui
  full_name: Li, Tonghui
  last_name: Li
- first_name: Linfan
  full_name: Zhang, Linfan
  last_name: Zhang
- first_name: Tong
  full_name: Chen, Tong
  last_name: Chen
- first_name: Chenglin
  full_name: Wang, Chenglin
  last_name: Wang
- first_name: Jian
  full_name: Yang, Jian
  last_name: Yang
- first_name: Jiaqi
  full_name: Gao, Jiaqi
  last_name: Gao
- first_name: Xiang
  full_name: Li, Xiang
  id: 4B7E523C-F248-11E8-B48F-1D18A9856A87
  last_name: Li
- first_name: Junhui
  full_name: Zhou, Junhui
  last_name: Zhou
- first_name: Yonghong
  full_name: Zhang, Yonghong
  last_name: Zhang
- first_name: Yu
  full_name: Liu, Yu
  id: 2A70014E-F248-11E8-B48F-1D18A9856A87
  last_name: Liu
  orcid: 0000-0001-7313-6740
- first_name: Yuan
  full_name: Wang, Yuan
  last_name: Wang
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Chen
  full_name: Li, Chen
  last_name: Li
- first_name: Lin
  full_name: Xu, Lin
  last_name: Xu
- first_name: Luqi
  full_name: Huang, Luqi
  last_name: Huang
citation:
  ama: Liu J, Zhai N, Zhang S, et al. Single-cell analyses identify the ginseng embryonic
    protoderm as a native compartment for high-efficiency ginsenoside production.
    <i>Nature Communications</i>. 2026;17. doi:<a href="https://doi.org/10.1038/s41467-026-74881-5">10.1038/s41467-026-74881-5</a>
  apa: Liu, J., Zhai, N., Zhang, S., Tamada, Y., Li, T., Zhang, L., … Huang, L. (2026).
    Single-cell analyses identify the ginseng embryonic protoderm as a native compartment
    for high-efficiency ginsenoside production. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-026-74881-5">https://doi.org/10.1038/s41467-026-74881-5</a>
  chicago: Liu, Juan, Ning Zhai, Shiyi Zhang, Yosuke Tamada, Tonghui Li, Linfan Zhang,
    Tong Chen, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm
    as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature
    Communications</i>. Springer Nature, 2026. <a href="https://doi.org/10.1038/s41467-026-74881-5">https://doi.org/10.1038/s41467-026-74881-5</a>.
  ieee: J. Liu <i>et al.</i>, “Single-cell analyses identify the ginseng embryonic
    protoderm as a native compartment for high-efficiency ginsenoside production,”
    <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.
  ista: Liu J, Zhai N, Zhang S, Tamada Y, Li T, Zhang L, Chen T, Wang C, Yang J, Gao
    J, Li X, Zhou J, Zhang Y, Liu Y, Wang Y, Friml J, Benková E, Li C, Xu L, Huang
    L. 2026. Single-cell analyses identify the ginseng embryonic protoderm as a native
    compartment for high-efficiency ginsenoside production. Nature Communications.
    17, 7994.
  mla: Liu, Juan, et al. “Single-Cell Analyses Identify the Ginseng Embryonic Protoderm
    as a Native Compartment for High-Efficiency Ginsenoside Production.” <i>Nature
    Communications</i>, vol. 17, 7994, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41467-026-74881-5">10.1038/s41467-026-74881-5</a>.
  short: J. Liu, N. Zhai, S. Zhang, Y. Tamada, T. Li, L. Zhang, T. Chen, C. Wang,
    J. Yang, J. Gao, X. Li, J. Zhou, Y. Zhang, Y. Liu, Y. Wang, J. Friml, E. Benková,
    C. Li, L. Xu, L. Huang, Nature Communications 17 (2026).
das_tickbox: '1'
dataavailabilitystatement: The RNA-seq data generated in this study have been deposited
  in the GSA database under accession code CRA008967. The scRNA-seq data generated
  in this study have been deposited in the GSA database under accession code CRA026200.
  The ATAC-seq data generated in this study have been deposited in the GSA database
  under accession code CRA008969. The ChIP-seq data generated in this study have been
  deposited in the GSA database under accession code CRA008968. Single-cell RNA-seq
  data and scripts are publicly available on Zenodo (https://zenodo.org/records/20392012).
  Primers are in Supplemental Table 5. Source data are provided with this paper.
date_created: 2026-08-16T22:01:42Z
date_published: 2026-08-07T00:00:00Z
date_updated: 2026-08-20T06:45:46Z
day: '07'
ddc:
- '580'
department:
- _id: JiFr
- _id: EvBe
doi: 10.1038/s41467-026-74881-5
external_id:
  pmid:
  - '42350386'
file:
- access_level: open_access
  checksum: 0b4ff29f0d0168b11be32a5f22ded9e4
  content_type: application/pdf
  creator: dernst
  date_created: 2026-08-20T06:44:33Z
  date_updated: 2026-08-20T06:44:33Z
  file_id: '22742'
  file_name: 2026_NatureComm_Liu.pdf
  file_size: 2429551
  relation: main_file
  success: 1
file_date_updated: 2026-08-20T06:44:33Z
has_accepted_license: '1'
intvolume: '        17'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Single-cell analyses identify the ginseng embryonic protoderm as a native compartment
  for high-efficiency ginsenoside production
tmp:
  image: /images/cc_by_nc_nd.png
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    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '22711'
abstract:
- lang: eng
  text: When charge flows through a molecular circuit, it induces a magnetic field
    that allows the circuit to behave as a nanoscale electromagnet. However, in single-molecule
    circuits this magnetic field is usually weak. Here we show that radially π-conjugated
    carbon structures can support amplified circulating currents that generate local
    magnetic fields. Within tight-binding and density functional theory (DFT) frameworks,
    we first study cycloparaphenylene (CPP) junctions where both electrodes are attached
    to the same phenylene unit on the nanohoop. We observe an energy-dependent ring
    current component that traverses the whole macrocycle by mapping the local current
    density. Importantly, we find that destructive interference near degenerate resonances
    can reverse the ring current direction and amplify it strongly relative to the
    source–drain current. We show that this interference-driven design principle is
    general, and also carries over to C60 junctions. In fullerene, lower-lying degenerate
    resonances are more easily accessible through electrostatic gating, reaching a
    magnetic field of 14.2 mT under a 100 mV source–drain bias. This work thus provides
    new insights into ring currents in radially π-conjugated carbon structures and
    highlights their potential as design platforms for single-molecule electromagnets.
acknowledgement: The authors thank Jascha Repp from the University of Regensburg for
  helpful discussions. This paper is dedicated to the memory of Prof. Mark Ratner
  in appreciation of the encouragement offered many years ago, and whose influence
  had endured ever since. This work was supported by the National Science Foundation
  under grant NSF-DMR 2241180 and the Institute of Science and Technology Austria.
  The collaboration between L.V., R.K., and F.E. was supported by the Humboldt Foundation.
  This research was funded in part by the Austrian Science Fund (FWF) [10.55776/COE5]
  (Cluster of Excellence MECS).
article_number: '7916'
article_processing_charge: Yes
article_type: original
author:
- first_name: Wanzhuo
  full_name: Shi, Wanzhuo
  id: a3010425-87c8-11f0-8106-bec32bea74da
  last_name: Shi
- first_name: Richard
  full_name: Korytár, Richard
  last_name: Korytár
- first_name: Ferdinand
  full_name: Evers, Ferdinand
  last_name: Evers
- first_name: John D.
  full_name: Tovar, John D.
  last_name: Tovar
- first_name: Latha
  full_name: Venkataraman, Latha
  id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
  last_name: Venkataraman
  orcid: 0000-0002-6957-6089
citation:
  ama: Shi W, Korytár R, Evers F, Tovar JD, Venkataraman L. Designing effective single-molecule
    electromagnets with radially π-conjugated carbon structures. <i>Nature Communications</i>.
    2026;17. doi:<a href="https://doi.org/10.1038/s41467-026-74365-6">10.1038/s41467-026-74365-6</a>
  apa: Shi, W., Korytár, R., Evers, F., Tovar, J. D., &#38; Venkataraman, L. (2026).
    Designing effective single-molecule electromagnets with radially π-conjugated
    carbon structures. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-026-74365-6">https://doi.org/10.1038/s41467-026-74365-6</a>
  chicago: Shi, Wanzhuo, Richard Korytár, Ferdinand Evers, John D. Tovar, and Latha
    Venkataraman. “Designing Effective Single-Molecule Electromagnets with Radially
    π-Conjugated Carbon Structures.” <i>Nature Communications</i>. Springer Nature,
    2026. <a href="https://doi.org/10.1038/s41467-026-74365-6">https://doi.org/10.1038/s41467-026-74365-6</a>.
  ieee: W. Shi, R. Korytár, F. Evers, J. D. Tovar, and L. Venkataraman, “Designing
    effective single-molecule electromagnets with radially π-conjugated carbon structures,”
    <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.
  ista: Shi W, Korytár R, Evers F, Tovar JD, Venkataraman L. 2026. Designing effective
    single-molecule electromagnets with radially π-conjugated carbon structures. Nature
    Communications. 17, 7916.
  mla: Shi, Wanzhuo, et al. “Designing Effective Single-Molecule Electromagnets with
    Radially π-Conjugated Carbon Structures.” <i>Nature Communications</i>, vol. 17,
    7916, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41467-026-74365-6">10.1038/s41467-026-74365-6</a>.
  short: W. Shi, R. Korytár, F. Evers, J.D. Tovar, L. Venkataraman, Nature Communications
    17 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: The data generated in this study have been deposited in
  the Code Ocean capsule. The capsule contains the FHI-aims and AITRANSS output matrices
  used for post-processing, precomputed cache files, and optimized atomic coordinate
  files. These data are sufficient to reproduce the results reported in the paper.
  The code used to reproduce the local-current and magnetic-field analyses is available
  in the Code Ocean capsule. The capsule includes Python scripts for post-processing
  DFT output matrices and Mathematica notebooks for tight-binding calculations and
  reproducing visualizations.
date_created: 2026-08-16T22:01:42Z
date_published: 2026-08-06T00:00:00Z
date_updated: 2026-08-20T06:40:49Z
day: '06'
ddc:
- '530'
department:
- _id: LaVe
doi: 10.1038/s41467-026-74365-6
external_id:
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  - '42277037'
file:
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intvolume: '        17'
language:
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month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Designing effective single-molecule electromagnets with radially π-conjugated
  carbon structures
tmp:
  image: /images/cc_by_nc_nd.png
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  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
OA_place: repository
_id: '22687'
abstract:
- lang: eng
  text: "Understanding enzyme function requires characterizing not only static structure
    but also dynamics and ligand interactions. NMR spectroscopy provides this insight
    at atomic resolution, yet for large proteins the difficulty of resonance assignment
    has largely confined such studies to systems below ∼50 kDa, or to observing only
    methyl groups. Here we present an integrated magic-angle spinning (MAS) and solution
    NMR study of the 134 kDa tetrameric malate dehydrogenase from Ignicoccus islandicus
    (IiMDH), an enzyme of particular interest as an evolutionary intermediate between
    allosteric lactate\r\ndehydrogenases and non-allosteric malate dehydrogenases.
    By combining high-dimensional (up to 4D) MAS NMR experiments on sedimented protein
    with solution NMR, we achieved 92% backbone heavy- atom assignment and 91% assignment
    of all Ile-δ1, Leu-δ1/-δ2, Val-γ1/-γ2, Met-ε and Thr-γ methyl groups. Building
    on these assignments, we use various probes of backbone and sidechain dynamics:
    elevated MAS NMR 15N rotating-frame relaxation (R1ρ) points to microsecond motions
    in functionally critical regions, including the catalytic loop and the mobile
    surface loop. Complementary methyl-axis order parameters from solution NMR identified
    additional flexible sites in the hydrophobic core. Chemical shift perturbation
    experiments upon addition of the substrate analogue oxamate, monitored via backbone
    1H-15N TROSY, revealed both active-site contacts and responses in helices α2F
    and α3G, regions implicated in allosteric signal transmission. The integrated
    approach demonstrated here exploits the distinct strengths of MAS and solution
    NMR, and provides a comprehensive view of structure, dynamics, and substrate interactions
    in a large oligomeric enzyme that would not be accessible by either technique
    alone."
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: This research was supported by the Scientific Service Units (SSU)
  of Institute of Science and Technology Austria (ISTA) through resources provided
  by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra
  Rovó, Megha Mohan and Margarita Valhondo Falcón for excellent support of the NMR
  facility.
article_processing_charge: No
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Federico
  full_name: Napoli, Federico
  id: d42e08e7-f4fc-11eb-af0a-d71e26138f1b
  last_name: Napoli
  orcid: 0000-0002-9043-136X
citation:
  ama: 'Schanda P, Napoli F. Data and scripts for: “Integrated solid/solution NMR
    assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.” 2026.
    doi:<a href="https://doi.org/10.15479/AT-ISTA-22687">10.15479/AT-ISTA-22687</a>'
  apa: 'Schanda, P., &#38; Napoli, F. (2026). Data and scripts for: “Integrated solid/solution
    NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.”
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22687">https://doi.org/10.15479/AT-ISTA-22687</a>'
  chicago: 'Schanda, Paul, and Federico Napoli. “Data and Scripts for: ‘Integrated
    Solid/Solution NMR Assignment Allows Mapping Dynamics and Ligand Binding in a
    134 KDa Enzyme.’” Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22687">https://doi.org/10.15479/AT-ISTA-22687</a>.'
  ieee: 'P. Schanda and F. Napoli, “Data and scripts for: ‘Integrated solid/solution
    NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme.’”
    Institute of Science and Technology Austria, 2026.'
  ista: 'Schanda P, Napoli F. 2026. Data and scripts for: ‘Integrated solid/solution
    NMR assignment allows mapping dynamics and ligand binding in a 134 kDa enzyme’,
    Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT-ISTA-22687">10.15479/AT-ISTA-22687</a>.'
  mla: 'Schanda, Paul, and Federico Napoli. <i>Data and Scripts for: “Integrated Solid/Solution
    NMR Assignment Allows Mapping Dynamics and Ligand Binding in a 134 KDa Enzyme.”</i>
    Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22687">10.15479/AT-ISTA-22687</a>.'
  short: P. Schanda, F. Napoli, (2026).
contributor:
- contributor_type: researcher
  first_name: Federico
  id: d42e08e7-f4fc-11eb-af0a-d71e26138f1b
  last_name: Napoli
  orcid: 0000-0002-9043-136X
- contributor_type: project_leader
  first_name: Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- contributor_type: project_member
  first_name: Rajkumar
  id: a3089acd-6806-11ee-bacc-f0c7d500ad20
  last_name: Singh
- contributor_type: project_member
  first_name: Anna
  id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
  last_name: Kapitonova
- contributor_type: project_member
  first_name: Virgil
  last_name: Aitenbichler
- contributor_type: project_member
  first_name: Giorgia
  id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
  last_name: Toscano
- contributor_type: data_collector
  first_name: Barbara
  last_name: Perrone
corr_author: '1'
date_created: 2026-08-12T16:12:19Z
date_published: 2026-08-20T00:00:00Z
date_updated: 2026-08-20T07:40:15Z
day: '20'
department:
- _id: PaSc
doi: 10.15479/AT-ISTA-22687
doi_confirm: '1'
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  date_created: 2026-08-18T07:15:59Z
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  date_created: 2026-08-20T07:35:05Z
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  file_size: 868
  relation: main_file
  success: 1
file_date_updated: 2026-08-20T07:35:05Z
has_accepted_license: '1'
month: '08'
oa: 1
oa_version: None
project:
- _id: eb9c82eb-77a9-11ec-83b8-aadd536561cf
  grant_number: I05812
  name: AlloSpace. The emergence and mechanisms of allostery
publisher: Institute of Science and Technology Austria
status: public
title: 'Data and scripts for: "Integrated solid/solution NMR assignment allows mapping
  dynamics and ligand binding in a 134 kDa enzyme"'
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21746'
abstract:
- lang: eng
  text: As vertebrates transitioned from water to land, locomotion shifted from undulatory
    swimming to limb-based movement. How spinal circuits and their cell types evolved
    to support this transition remains unclear. We leverage frog metamorphosis, which
    recapitulates this transition within a single organism, to define how spinal circuits
    generate aquatic versus terrestrial motor patterns. At swim stages, spinal architecture
    is uniform, with a transcriptionally and anatomically homogeneous motor and interneurons.
    As limbs develop and their movement complexifies, spinal circuits expand in neuron
    number and subtype diversity. This expansion is most pronounced for V1 inhibitory
    neurons, which increase ∼70-fold and diversify into transcriptionally distinct
    subtypes. Disrupting transcription factors defining emerging motor and V1 populations
    reveals molecular segregation between swim and limb circuits, highlighting the
    role of subtype diversity in motor coordination. A multifold increase in inhibitory
    neuron diversity thus underlies the tail-to-limb locomotor transition, providing
    a framework for spinal circuit adaptation during vertebrate evolution.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: 'We would like to thank the members of the Sweeney Lab, Mario de
  Bono, Michael Forsthofer, Katharina Lust, and Meital Oren, for comments on the manuscript.
  We are also grateful to Tom Jessell and Chris Kintner for their scientific insight
  and mentorship during the conception of this project. It would also have not been
  possible without the technical support of the Aquatics and Imaging and Optics Facility
  support teams (ISTA). We thank Martin Estermann for preparing the initial draft
  of the graphical abstract and Niki Barolini for the final version. In addition,
  we thank our funding sources for providing the resources to do these experiments:
  GFF NÖ FTI Strategy Lower Austria dissertation grant FT121-D-046 (to D.V.), Horizon
  Europe ERC starting grant 101041551 (to Y.I., L.B.S., F.A.T., and D.V.), Special
  Research Program (SFB) of the Austrian Science Fund (FWF) project F7814-B (to L.B.S.),
  Austrian Science Fund (FWF) 10.55776/COE16 (to Y.I. and L.B.S.), NINDS 5R35NS116858
  (to J.S.D.), CZI grant DAF2020-225401 (DOI) 10.37921/120055ratwvi (to R.H.), NIH
  grant R01NS123116 (to J.B.B.), American Lebanese Syrian Associated Charities (ALSAC)
  (to J.B.B.), German Academic Exchange Service (DAAD) IFI grant 57515251-91853472
  (to Z.H.), and Project A.L.S. (to S.B.-M.).'
article_number: '117227'
article_processing_charge: Yes
article_type: original
author:
- first_name: David
  full_name: Vijatovic, David
  id: cf391e77-ec3c-11ea-a124-d69323410b58
  last_name: Vijatovic
  orcid: 0000-0002-5494-0941
- first_name: 'Florina Alexandra '
  full_name: 'Toma, Florina Alexandra '
  id: 2f73f876-f128-11eb-9611-b96b5a30cb0e
  last_name: Toma
- first_name: Y
  full_name: Ignatyev, Y
  last_name: Ignatyev
- first_name: Zoe P
  full_name: Harrington, Zoe P
  id: a8144562-32c9-11ee-b5ce-d9800628bda2
  last_name: Harrington
  orcid: 0009-0008-0158-4032
- first_name: Christoph M
  full_name: Sommer, Christoph M
  id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
  last_name: Sommer
  orcid: 0000-0003-1216-9105
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Matthijs Geert
  full_name: Smits, Matthijs Geert
  id: 7a231d52-e216-11ee-a0bb-8acd55f8f1f0
  last_name: Smits
- first_name: Marco
  full_name: Dalla Vecchia, Marco
  id: 02a7a869-ff06-11ed-a87f-86649d6077e5
  last_name: Dalla Vecchia
- first_name: Alexandra J.
  full_name: Trevisan, Alexandra J.
  last_name: Trevisan
- first_name: Phillip
  full_name: Chapman, Phillip
  last_name: Chapman
- first_name: Mara
  full_name: Julseth, Mara
  id: 1cf464b2-dc7d-11ea-9b2f-f9b1aa9417d1
  last_name: Julseth
- first_name: Susan
  full_name: Brenner-Morton, Susan
  last_name: Brenner-Morton
- first_name: Mariano I.
  full_name: Gabitto, Mariano I.
  last_name: Gabitto
- first_name: Jeremy S.
  full_name: Dasen, Jeremy S.
  last_name: Dasen
- first_name: Jay B.
  full_name: Bikoff, Jay B.
  last_name: Bikoff
- first_name: Lora Beatrice Jaeger
  full_name: Sweeney, Lora Beatrice Jaeger
  id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
  last_name: Sweeney
  orcid: 0000-0001-9242-5601
citation:
  ama: Vijatovic D, Toma FA, Ignatyev Y, et al. Multifold increase in spinal inhibitory
    cell types with emergence of limb movement. <i>Cell Reports</i>. 2026;45(4). doi:<a
    href="https://doi.org/10.1016/j.celrep.2026.117227">10.1016/j.celrep.2026.117227</a>
  apa: Vijatovic, D., Toma, F. A., Ignatyev, Y., Harrington, Z. P., Sommer, C. M.,
    Hauschild, R., … Sweeney, L. B. (2026). Multifold increase in spinal inhibitory
    cell types with emergence of limb movement. <i>Cell Reports</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.celrep.2026.117227">https://doi.org/10.1016/j.celrep.2026.117227</a>
  chicago: Vijatovic, David, Florina Alexandra  Toma, Y Ignatyev, Zoe P Harrington,
    Christoph M Sommer, Robert Hauschild, Matthijs Geert Smits, et al. “Multifold
    Increase in Spinal Inhibitory Cell Types with Emergence of Limb Movement.” <i>Cell
    Reports</i>. Elsevier, 2026. <a href="https://doi.org/10.1016/j.celrep.2026.117227">https://doi.org/10.1016/j.celrep.2026.117227</a>.
  ieee: D. Vijatovic <i>et al.</i>, “Multifold increase in spinal inhibitory cell
    types with emergence of limb movement,” <i>Cell Reports</i>, vol. 45, no. 4. Elsevier,
    2026.
  ista: Vijatovic D, Toma FA, Ignatyev Y, Harrington ZP, Sommer CM, Hauschild R, Smits
    MG, Dalla Vecchia M, Trevisan AJ, Chapman P, Julseth M, Brenner-Morton S, Gabitto
    MI, Dasen JS, Bikoff JB, Sweeney LB. 2026. Multifold increase in spinal inhibitory
    cell types with emergence of limb movement. Cell Reports. 45(4), 117227.
  mla: Vijatovic, David, et al. “Multifold Increase in Spinal Inhibitory Cell Types
    with Emergence of Limb Movement.” <i>Cell Reports</i>, vol. 45, no. 4, 117227,
    Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.celrep.2026.117227">10.1016/j.celrep.2026.117227</a>.
  short: D. Vijatovic, F.A. Toma, Y. Ignatyev, Z.P. Harrington, C.M. Sommer, R. Hauschild,
    M.G. Smits, M. Dalla Vecchia, A.J. Trevisan, P. Chapman, M. Julseth, S. Brenner-Morton,
    M.I. Gabitto, J.S. Dasen, J.B. Bikoff, L.B. Sweeney, Cell Reports 45 (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:43Z
date_published: 2026-04-28T00:00:00Z
date_updated: 2026-08-20T14:45:18Z
day: '28'
ddc:
- '570'
department:
- _id: LoSw
- _id: GradSch
- _id: TiVo
- _id: Bio
- _id: NiBa
doi: 10.1016/j.celrep.2026.117227
external_id:
  pmid:
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language:
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month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: ebb66355-77a9-11ec-83b8-b8ac210a4dae
  grant_number: '101041551'
  name: Development and Evolution of Tetrapod Motor Circuits
- _id: 8da85f50-16d5-11f0-9cad-eab8b0ff6c9e
  grant_number: F7814
  name: 'Stem Cell Modulation in Neural Development and Regeneration/ P14-Swim-to-limb
    transition: cell type to connection diversity'
- _id: c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473
  grant_number: CZI01
  name: Tools for automation and feedback microscopy
- _id: bd73af52-d553-11ed-ba76-912049f0ac7a
  grant_number: FTI21-D-046
  name: Development of V1 interneuron diversity during swim-to-walk transition of
    Xenopus metamorphosis
publication: Cell Reports
publication_identifier:
  eissn:
  - 2211-1247
  issn:
  - 2639-1856
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
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    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Multifold increase in spinal inhibitory cell types with emergence of limb movement
tmp:
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  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2026'
...
---
OA_place: publisher
_id: '22667'
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "I am also grateful for the financial support that made this work
  possible, including the\r\nEuropean Research Council (ERC Starting Grant 101041551),
  the Austrian Science\r\nFund (FWF, Cluster of Excellence 10.55776/COE16), the GFF
  Lower Austria FTI\r\nStrategy Dissertation Fellowship (FTI21-D-046), and the FENS/IBRO-PERC\r\nExchange
  Fellowship. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: David
  full_name: Vijatovic, David
  id: cf391e77-ec3c-11ea-a124-d69323410b58
  last_name: Vijatovic
  orcid: 0000-0002-5494-0941
citation:
  ama: Vijatovic D. Dissecting the molecular and functional basis of motor control
    in the frog Xenopus laevis. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22667">10.15479/AT-ISTA-22667</a>
  apa: Vijatovic, D. (2026). <i>Dissecting the molecular and functional basis of motor
    control in the frog Xenopus laevis</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-22667">https://doi.org/10.15479/AT-ISTA-22667</a>
  chicago: Vijatovic, David. “Dissecting the Molecular and Functional Basis of Motor
    Control in the Frog Xenopus Laevis.” Institute of Science and Technology Austria,
    2026. <a href="https://doi.org/10.15479/AT-ISTA-22667">https://doi.org/10.15479/AT-ISTA-22667</a>.
  ieee: D. Vijatovic, “Dissecting the molecular and functional basis of motor control
    in the frog Xenopus laevis,” Institute of Science and Technology Austria, 2026.
  ista: Vijatovic D. 2026. Dissecting the molecular and functional basis of motor
    control in the frog Xenopus laevis. Institute of Science and Technology Austria.
  mla: Vijatovic, David. <i>Dissecting the Molecular and Functional Basis of Motor
    Control in the Frog Xenopus Laevis</i>. Institute of Science and Technology Austria,
    2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22667">10.15479/AT-ISTA-22667</a>.
  short: D. Vijatovic, Dissecting the Molecular and Functional Basis of Motor Control
    in the Frog Xenopus Laevis, Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-08-10T13:44:30Z
date_published: 2026-08-10T00:00:00Z
date_updated: 2026-08-20T14:45:18Z
day: '10'
ddc:
- '573'
degree_awarded: PhD
department:
- _id: GradSch
- _id: LoSw
doi: 10.15479/AT-ISTA-22667
doi_confirm: '1'
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- iso: eng
month: '08'
oa_version: Published Version
page: '172'
project:
- _id: ebb66355-77a9-11ec-83b8-b8ac210a4dae
  grant_number: '101041551'
  name: Development and Evolution of Tetrapod Motor Circuits
- _id: bd73af52-d553-11ed-ba76-912049f0ac7a
  grant_number: FTI21-D-046
  name: Development of V1 interneuron diversity during swim-to-walk transition of
    Xenopus metamorphosis
- _id: 34a02c70-11ca-11ed-8bc3-fbfd2c86c88f
  grant_number: 3(GG016346-01)
  name: Development of Viral Vectors for Amphibian Gene Delivery and Manipulation
publication_identifier:
  isbn:
  - 978-3-99078-082-4
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '21746'
    relation: part_of_dissertation
    status: public
  - id: '15016'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Lora Beatrice Jaeger
  full_name: Sweeney, Lora Beatrice Jaeger
  id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
  last_name: Sweeney
  orcid: 0000-0001-9242-5601
title: Dissecting the molecular and functional basis of motor control in the frog
  Xenopus laevis
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
_id: '22664'
abstract:
- lang: eng
  text: "The widespread adoption of apps like Whatsapp and Signal has translated into
    billions of people all around the world communicating on a regular basis by making
    use of services that offer end-to-end encryption and even provide security guarantees
    when a user's device is compromised.\r\n\r\nThis was made possible by the introduction
    of the Double Ratchet Algorithm~\\cite{double_ratchet}, which was designed for
    a setting where communication takes place between two parties.\r\nHowever, in
    practice, many apps offer the possibility of creating groups.\r\nThe protocols
    they use to secure communication are inefficient for large group which has the
    undesireable consequence that the aforementioned apps have established limits
    on the group size of roughly 1000 users.\r\nThis has motivated the introduction
    of the Messaging Layer Security (MLS) standard~\\cite{rfc9420} by the IETF which
    is based on a primitive called Continuous Group Key Agreement (CGKA)~\\cite{C:ACDT20}.\r\n\r\nThis
    primitive allows a group of users to maintain a shared secret key that is frequently
    rotated by the group members in order to change group membership, achieve forward
    secrecy (FS) and post compromise security (PCS).\r\nMost protocols are based on
    binary trees where the nodes are associated to a pair formed by public key and
    a secret key.\r\nEach leaf corresponds to one of the group members and a user
    knows the secret keys associated to nodes along the path from their leaf to the
    root.\r\nWhen a user wants to update their key material they have to change $
    \\log(N) $ many keys.\r\nThis requires uploading $ \\log(N) $ many ciphertexts
    to communicate the new keys to the rest of the group members in a way that respects
    the tree structure.\r\n\r\nIn this thesis we study how much communication between
    group members is required in order to add and remove users from a group as well
    as in order to provide PCS when we consider CGKAs built using standard cryptographic
    primitives like pseudo-random functions and public-key encryption. Furthermore,
    we also consider the case of MLS and provide the first lower bound showing that
    its communication complexity is much worse than previously believed, i.e., it
    is very far from $ \\log(N) $.\r\nFinally, we also propose a variant of MLS which
    provably achieves the same security properties with a much lower communication
    cost."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Miguel
  full_name: Cueto Noval, Miguel
  id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc
  last_name: Cueto Noval
  orcid: 0000-0002-2505-4246
citation:
  ama: Cueto Noval M. Towards efficient secure group messaging. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22664">10.15479/AT-ISTA-22664</a>
  apa: Cueto Noval, M. (2026). <i>Towards efficient secure group messaging</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22664">https://doi.org/10.15479/AT-ISTA-22664</a>
  chicago: Cueto Noval, Miguel. “Towards Efficient Secure Group Messaging.” Institute
    of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22664">https://doi.org/10.15479/AT-ISTA-22664</a>.
  ieee: M. Cueto Noval, “Towards efficient secure group messaging,” Institute of Science
    and Technology Austria, 2026.
  ista: Cueto Noval M. 2026. Towards efficient secure group messaging. Institute of
    Science and Technology Austria.
  mla: Cueto Noval, Miguel. <i>Towards Efficient Secure Group Messaging</i>. Institute
    of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22664">10.15479/AT-ISTA-22664</a>.
  short: M. Cueto Noval, Towards Efficient Secure Group Messaging, Institute of Science
    and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-08-10T10:18:35Z
date_published: 2026-08-10T00:00:00Z
date_updated: 2026-08-21T10:53:17Z
day: '10'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrPi
doi: 10.15479/AT-ISTA-22664
doi_confirm: '1'
file:
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  file_name: 2026_CuetoNoval_Miguel_Thesis.pdf
  file_size: 1390255
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  checksum: 4d6def422cc93a108faf5e5defc0f807
  content_type: application/zip
  creator: mcuetono
  date_created: 2026-08-13T09:39:01Z
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  file_size: 9923509
  relation: source_file
file_date_updated: 2026-08-19T11:36:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '187'
publication_identifier:
  isbn:
  - ' 978-3-99078-087-9'
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '14691'
    relation: part_of_dissertation
    status: public
  - id: '18702'
    relation: part_of_dissertation
    status: public
  - id: '21262'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
title: Towards efficient secure group messaging
tmp:
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  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '18706'
abstract:
- lang: eng
  text: "We prove discrete-to-continuum convergence for dynamical optimal transport
    on  Zd\r\n -periodic graphs with cost functional having linear growth at infinity.
    This result provides an answer to a problem left open by Gladbach, Kopfer, Maas,
    and Portinale (Calc Var Partial Differential Equations 62(5), 2023), where the
    convergence behaviour of discrete boundary-value dynamical transport problems
    is proved under the stronger assumption of superlinear growth. Our result extends
    the known literature to some important classes of examples, such as scaling limits
    of  1 -Wasserstein transport problems. Similarly to what happens in the quadratic
    case, the geometry of the graph plays a crucial role in the structure of the limit
    cost function, as we discuss in the final part of this work, which includes some
    visual representations."
acknowledgement: L.P. gratefully acknowledges fundings from the Deutsche Forschungsgemeinschaft
  (DFG, German Research Foundation) under Germany’s Excellence Strategy – GZ 2047/1,
  Projekt-ID 390685813. F.Q. gratefully acknowledges support from the Austrian Science
  Fund (FWF) project 10.55776/F65.
article_processing_charge: Yes
article_type: original
author:
- first_name: Lorenzo
  full_name: Portinale, Lorenzo
  id: 30AD2CBC-F248-11E8-B48F-1D18A9856A87
  last_name: Portinale
- first_name: Filippo
  full_name: Quattrocchi, Filippo
  id: 3ebd6ba8-edfb-11eb-afb5-91a9745ba308
  last_name: Quattrocchi
  orcid: 0009-0000-9773-1931
citation:
  ama: Portinale L, Quattrocchi F. Discrete-to-continuum limits of optimal transport
    with linear growth on periodic graphs. <i>European Journal of Applied Mathematics</i>.
    2026;37(3):614-642. doi:<a href="https://doi.org/10.1017/s0956792524000810">10.1017/s0956792524000810</a>
  apa: Portinale, L., &#38; Quattrocchi, F. (2026). Discrete-to-continuum limits of
    optimal transport with linear growth on periodic graphs. <i>European Journal of
    Applied Mathematics</i>. Cambridge University Press. <a href="https://doi.org/10.1017/s0956792524000810">https://doi.org/10.1017/s0956792524000810</a>
  chicago: Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits
    of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal
    of Applied Mathematics</i>. Cambridge University Press, 2026. <a href="https://doi.org/10.1017/s0956792524000810">https://doi.org/10.1017/s0956792524000810</a>.
  ieee: L. Portinale and F. Quattrocchi, “Discrete-to-continuum limits of optimal
    transport with linear growth on periodic graphs,” <i>European Journal of Applied
    Mathematics</i>, vol. 37, no. 3. Cambridge University Press, pp. 614–642, 2026.
  ista: Portinale L, Quattrocchi F. 2026. Discrete-to-continuum limits of optimal
    transport with linear growth on periodic graphs. European Journal of Applied Mathematics.
    37(3), 614–642.
  mla: Portinale, Lorenzo, and Filippo Quattrocchi. “Discrete-to-Continuum Limits
    of Optimal Transport with Linear Growth on Periodic Graphs.” <i>European Journal
    of Applied Mathematics</i>, vol. 37, no. 3, Cambridge University Press, 2026,
    pp. 614–42, doi:<a href="https://doi.org/10.1017/s0956792524000810">10.1017/s0956792524000810</a>.
  short: L. Portinale, F. Quattrocchi, European Journal of Applied Mathematics 37
    (2026) 614–642.
das_tickbox: '0'
date_created: 2024-12-23T11:03:59Z
date_published: 2026-06-01T00:00:00Z
date_updated: 2026-08-25T22:31:05Z
day: '01'
ddc:
- '500'
department:
- _id: GradSch
- _id: JaMa
doi: 10.1017/s0956792524000810
external_id:
  isi:
  - '001381435800001'
file:
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  checksum: d038f4d00cbfbde2672c17138eab21c9
  content_type: application/pdf
  creator: dernst
  date_created: 2026-07-23T05:55:03Z
  date_updated: 2026-07-23T05:55:03Z
  file_id: '22386'
  file_name: 2026_EuropJourAppliedMath_Portinale.pdf
  file_size: 612317
  relation: main_file
  success: 1
file_date_updated: 2026-07-23T05:55:03Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '3'
keyword:
- optimal transport
- discrete-to-continuum
- homogenisation
- linear growth
- gamma-convergence
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 614-642
project:
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
publication: European Journal of Applied Mathematics
publication_identifier:
  eissn:
  - 1469-4425
  issn:
  - 0956-7925
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
related_material:
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  - id: '20563'
    relation: dissertation_contains
    status: public
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Discrete-to-continuum limits of optimal transport with linear growth on periodic
  graphs
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2026'
...
---
OA_place: publisher
_id: '22694'
abstract:
- lang: eng
  text: "We develop and employ techniques from equivariant algebraic K-theory and
    related invariants\r\nin the context of geometric representation theory, in both
    arithmetic and topological situations.\r\nWe showcase the use of such techniques
    on the affine Grassmannian Gr, a space of fundamental\r\ninterest in the geometric
    Langlands program.\r\n\r\nIt is a deep development of mathematics of the last
    century that many concrete, yet combina-\r\ntorially complex algebraic problems
    may be effectively studied through the lens of algebraic\r\ngeometry. The objects
    of interest can be often realized as cohomological invariants of algebraic\r\nvarieties,
    and good understanding of their geometry sheds light into the original questions.\r\nSuch
    techniques have seen immense applications in the Langlands program, where they
    go\r\nunder the label of geometric representation theory.\r\n\r\nOne source of
    powerful invariants in algebraic geometry comes from algebraic K-theory,\r\nHochschild
    homology, and their relatives. These localizing invariants contain large amount\r\nof
    information, but are quite hard to compute. For this reason, their usage in geometric\r\nrepresentation
    theory has been limited.\r\n\r\nThe aim of this thesis is to showcase how to control
    such invariants in the situations of\r\ninterest and use them to obtain new insights.
    We start by reinterpreting equivariant Hochschild\r\nhomology in terms of functions
    on certain fixed-point schemes, which are of independent\r\ninterest. We compare
    it to equivariant K-theory via the trace map. We give new computations\r\nand
    comparisons of such invariants of affine Schubert varieties in Gr, including arithmetic\r\nsituations.
    We show that they behave much better than expected.\r\n\r\nWe finally utilize
    this circle of ideas in a purely topological setting. We describe the varying\r\nfixed
    points of the extended torus action on the affine Grassmannian, and use it to
    compute\r\nits equivariant topological K-theory ring. The answer is nontrivial
    and verifies an outstanding\r\nconjecture in the subject.\r\n\r\nWe compare, partly
    conjecturally, the resulting K-theory ring to the completed center of an\r\nintegral
    even hybrid quantum group and its deformed quantum category O. This gives a\r\ngenuine
    application of our computations in pure representation theory."
acknowledgement: "It was funded by a DOC Fellowship of the Austrian Academy of Sciences
  entitled Arithmetic,\r\ngeometry, topology and representation theory arising from
  the affine Grassmannian. It was\r\nfurther funded by the Austrian Science Fund FWF
  10.55776/P35847, and an Erasmus+ staff\r\nmobility training. \r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jakub
  full_name: Löwit, Jakub
  id: e3b80ae2-eb8e-11eb-b029-9aef4a9108a0
  last_name: Löwit
citation:
  ama: Löwit J. Equivariant K-theory of affine Grassmannians in representation theory
    and arithmetic. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22694">10.15479/AT-ISTA-22694</a>
  apa: Löwit, J. (2026). <i>Equivariant K-theory of affine Grassmannians in representation
    theory and arithmetic</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22694">https://doi.org/10.15479/AT-ISTA-22694</a>
  chicago: Löwit, Jakub. “Equivariant K-Theory of Affine Grassmannians in Representation
    Theory and Arithmetic.” Institute of Science and Technology Austria, 2026. <a
    href="https://doi.org/10.15479/AT-ISTA-22694">https://doi.org/10.15479/AT-ISTA-22694</a>.
  ieee: J. Löwit, “Equivariant K-theory of affine Grassmannians in representation
    theory and arithmetic,” Institute of Science and Technology Austria, 2026.
  ista: Löwit J. 2026. Equivariant K-theory of affine Grassmannians in representation
    theory and arithmetic. Institute of Science and Technology Austria.
  mla: Löwit, Jakub. <i>Equivariant K-Theory of Affine Grassmannians in Representation
    Theory and Arithmetic</i>. Institute of Science and Technology Austria, 2026,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-22694">10.15479/AT-ISTA-22694</a>.
  short: J. Löwit, Equivariant K-Theory of Affine Grassmannians in Representation
    Theory and Arithmetic, Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-08-12T14:05:36Z
date_published: 2026-08-05T00:00:00Z
date_updated: 2026-08-26T06:53:55Z
day: '05'
ddc:
- '510'
- '516'
- '512'
- '514'
- '513'
degree_awarded: PhD
department:
- _id: GradSch
- _id: TaHa
doi: 10.15479/AT-ISTA-22694
doi_confirm: '1'
file:
- access_level: open_access
  checksum: 2d0be77791dc296621c6c0f76be9d0d7
  content_type: application/pdf
  creator: jloewit
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  date_updated: 2026-08-14T11:42:31Z
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language:
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month: '08'
oa: 1
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page: '185'
project:
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  grant_number: '27004'
  name: Arithmetic, geometry, topology and representation theory arising from the
    affine Grassmannian
- _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3
  grant_number: P35847
  name: Geometry of the tip of the global nilpotent cone
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publisher_comment: "For open access purposes, the author has applied a CC BY public
  copyright\r\nlicense to any author-accepted manuscript version arising from this
  submission."
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status: public
supervisor:
- first_name: Tamás
  full_name: Hausel, Tamás
  id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
  last_name: Hausel
  orcid: 0000-0002-9582-2634
title: Equivariant K-theory of affine Grassmannians in representation theory and arithmetic
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type: dissertation
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year: '2026'
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abstract:
- lang: eng
  text: 'We define a certain class of simple varieties over a field k by a constructive
    recipe and show how to control their (equivariant) truncating invariants. Consequently,
    we prove that on simple varieties: (i) if k = k and char k = p, the p-adic cyclotomic
    trace is an equivalence; (ii) if k = Q, the Goodwillie–Jones trace is an isomorphism
    in degree zero; (iii) we can control homotopy invariant K-theory KH, which is
    equivariantly formal and determined by its topological counterparts. Simple varieties
    are quite special, but encompass important singular examples appearing in geometric
    representation theory. We, in particular, show that both finite and affine Schubert
    varieties for GLn lie in this class, so all the above results hold for them. '
acknowledgement: "This work was supported by a DOC Fellowship of the Austrian Academy
  of Sciences at the Institute of Science and Technology Austria (ISTA) and by an
  Erasmus+ staff mobility training. It took place during the author’s visit to Laboratoire
  de Mathématiques d’Orsay in the course of his PhD at the Institute of Science and
  Technology Austria. First and foremost, I would like to thank Matthew Morrow for
  discussions, explanations and ideas without which this work would not have been
  carried out. I would further like to thank Brian Conrad for providing an amazing
  reference on projective cones in appropriate generality, to Vova Sosnilo for carefully
  discussing – among other things – the derived nilinvariance for quotients by any
  linearly reductive group, and to Adeel Khan, Timo Richarz, Matthias Wendt and Xinwen
  Zhu for helpful conversations\r\nabout the results. I would moreover like to thank
  the referee for the very useful comments."
article_number: rnag058
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Jakub
  full_name: Löwit, Jakub
  id: e3b80ae2-eb8e-11eb-b029-9aef4a9108a0
  last_name: Löwit
citation:
  ama: Löwit J. Equivariant localizing invariants of simple varieties. <i>International
    Mathematics Research Notices</i>. 2026;2026(7). doi:<a href="https://doi.org/10.1093/imrn/rnag058">10.1093/imrn/rnag058</a>
  apa: Löwit, J. (2026). Equivariant localizing invariants of simple varieties. <i>International
    Mathematics Research Notices</i>. Oxford University Press. <a href="https://doi.org/10.1093/imrn/rnag058">https://doi.org/10.1093/imrn/rnag058</a>
  chicago: Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.”
    <i>International Mathematics Research Notices</i>. Oxford University Press, 2026.
    <a href="https://doi.org/10.1093/imrn/rnag058">https://doi.org/10.1093/imrn/rnag058</a>.
  ieee: J. Löwit, “Equivariant localizing invariants of simple varieties,” <i>International
    Mathematics Research Notices</i>, vol. 2026, no. 7. Oxford University Press, 2026.
  ista: Löwit J. 2026. Equivariant localizing invariants of simple varieties. International
    Mathematics Research Notices. 2026(7), rnag058.
  mla: Löwit, Jakub. “Equivariant Localizing Invariants of Simple Varieties.” <i>International
    Mathematics Research Notices</i>, vol. 2026, no. 7, rnag058, Oxford University
    Press, 2026, doi:<a href="https://doi.org/10.1093/imrn/rnag058">10.1093/imrn/rnag058</a>.
  short: J. Löwit, International Mathematics Research Notices 2026 (2026).
corr_author: '1'
date_created: 2026-04-19T22:07:48Z
date_published: 2026-04-01T00:00:00Z
date_updated: 2026-08-26T06:53:54Z
day: '01'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1093/imrn/rnag058
external_id:
  arxiv:
  - '2507.09392'
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has_accepted_license: '1'
intvolume: '      2026'
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month: '04'
oa: 1
oa_version: Published Version
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- _id: 901e2a43-16d5-11f0-9cad-9cead34748d6
  grant_number: '27004'
  name: Arithmetic, geometry, topology and representation theory arising from the
    affine Grassmannian
publication: International Mathematics Research Notices
publication_identifier:
  eissn:
  - 1687-0247
  issn:
  - 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
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scopus_import: '1'
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title: Equivariant localizing invariants of simple varieties
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2026
year: '2026'
...
---
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OA_type: hybrid
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abstract:
- lang: eng
  text: We study torus-equivariant algebraic K-theory of affine Schubert varieties
    in the perfect affine Grassmannians over Fp. We further compare it to the torus-equivariant
    Hochschild homology of perfect complexes, which has a geometric description in
    terms of global functions on certain fixed-point schemes. We prove that Fp-linearly,
    this comparison is an isomorphism. Our approach is quite constructive, resulting
    in new computations of these K-theory rings. We establish various structural results
    for equivariant perfect algebraic K-theory on the way; we believe these are of
    independent interest.
acknowledgement: "I would like to thank the following people for fruitful discussions,\r\nhelpful
  sanity checks or comments on previous drafts: Roman Bezrukavnikov, Jens Niklas Eberhardt,
  Mischa Elkner, Tamás Hausel, Andres Fernandez Herrero, Adeel Khan,\r\nBernhard Köck,
  Andrei Konovalov, Quoc Ho, Mirko Mauri, Matthew Morrow, Charanya\r\nRavi, Kamil
  Rychlewicz, Shyiu Shen, Vladimir Sosnilo, Georg Tamme, Xinwen Zhu. I\r\nwould further
  like to thank Marc Hoyois and the anonymous referee for spotting an error\r\nin
  a previous version.\r\nThis work was done during author’s PhD at the Institute of
  Science and Technology Austria (ISTA). It was funded by a DOC Fellowship of the
  Austrian Academy\r\nof Sciences and by the Austrian Science Fund (FWF) 10.55776/P35847.
  For open access\r\npurposes, the author has applied a CC BY public copyright license
  to any author-accepted\r\nmanuscript version arising from this submission."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Jakub
  full_name: Löwit, Jakub
  id: e3b80ae2-eb8e-11eb-b029-9aef4a9108a0
  last_name: Löwit
citation:
  ama: Löwit J. Equivariant K-theory, affine Grassmannian and perfection. <i>Documenta
    Mathematica</i>. 2026. doi:<a href="https://doi.org/10.4171/dm/1064">10.4171/dm/1064</a>
  apa: Löwit, J. (2026). Equivariant K-theory, affine Grassmannian and perfection.
    <i>Documenta Mathematica</i>. EMS Press. <a href="https://doi.org/10.4171/dm/1064">https://doi.org/10.4171/dm/1064</a>
  chicago: Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.”
    <i>Documenta Mathematica</i>. EMS Press, 2026. <a href="https://doi.org/10.4171/dm/1064">https://doi.org/10.4171/dm/1064</a>.
  ieee: J. Löwit, “Equivariant K-theory, affine Grassmannian and perfection,” <i>Documenta
    Mathematica</i>. EMS Press, 2026.
  ista: Löwit J. 2026. Equivariant K-theory, affine Grassmannian and perfection. Documenta
    Mathematica.
  mla: Löwit, Jakub. “Equivariant K-Theory, Affine Grassmannian and Perfection.” <i>Documenta
    Mathematica</i>, EMS Press, 2026, doi:<a href="https://doi.org/10.4171/dm/1064">10.4171/dm/1064</a>.
  short: J. Löwit, Documenta Mathematica (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-08-12T13:29:17Z
date_published: 2026-03-26T00:00:00Z
date_updated: 2026-08-26T06:53:54Z
day: '26'
ddc:
- '500'
department:
- _id: GradSch
- _id: TaHa
doi: 10.4171/dm/1064
external_id:
  arxiv:
  - '2409.18925'
has_accepted_license: '1'
keyword:
- equivariant algebraic K-theory
- perfection in positive characteristic
- affine Grassmannian
- affine Schubert varieties
- Dennis trace map
- equivariant Hochschild homology
- fixed-point schemes
- toric varieties
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.4171/DM/1064
mathsc:
- '19E08'
- 19L47
- 20G44
- 14G17
- 19D55
- 14F43
- 14L30
- 14D24
- 14M25
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3
  grant_number: P35847
  name: Geometry of the tip of the global nilpotent cone
publication: Documenta Mathematica
publication_identifier:
  eissn:
  - 1431-0643
  issn:
  - 1431-0635
publication_status: epub_ahead
publisher: EMS Press
quality_controlled: '1'
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researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Equivariant K-theory, affine Grassmannian and perfection
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_type: closed access
_id: '21762'
abstract:
- lang: eng
  text: Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular
    organization. The plasmid-encoded ParMRC system forms actin-like filaments that
    segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena
    sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal
    system named CorMR with a function in cell shape control rather than DNA segregation.
    Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed
    that CorM formed dynamically unstable, antiparallel double-stranded filaments
    that were recruited to the membrane by CorR through an amphipathic helix conserved
    in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which
    excluded them from the poles and division plane. Comparative genomics indicated
    that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity,
    highlighting the evolutionary plasticity of cytoskeletal systems in bacteria.
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all members of the Loose lab at ISTA for helpful discussions;
  M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University)
  for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial
  strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial
  strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing
  the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix
  screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data
  collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work
  was supported by the Scientific Service Units (SSU) of ISTA through resources provided
  by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the
  Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work
  was funded by the European Union’s Horizon 2020 research and innovation program
  (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council
  (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National
  Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques
  et Letitia Lopez-Loreta Foundation (G.L.W.)."
article_number: eaea6343
article_processing_charge: No
article_type: original
author:
- first_name: Benjamin L
  full_name: Springstein, Benjamin L
  id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083
  last_name: Springstein
  orcid: 0000-0002-3461-5391
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
  orcid: 0000-0003-2311-2112
- first_name: Daniela
  full_name: Megrian, Daniela
  last_name: Megrian
- first_name: Roman
  full_name: Hajdu, Roman
  id: ffab949d-133f-11ed-8f02-94de21ace503
  last_name: Hajdu
- first_name: Dustin M.
  full_name: Hanke, Dustin M.
  last_name: Hanke
- first_name: Bettina
  full_name: Zens, Bettina
  id: 45FD126C-F248-11E8-B48F-1D18A9856A87
  last_name: Zens
  orcid: 0000-0002-9561-1239
- first_name: Gregor L.
  full_name: Weiss, Gregor L.
  last_name: Weiss
- first_name: Florian Km
  full_name: Schur, Florian Km
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
citation:
  ama: Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation
    machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795).
    doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>
  apa: Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens,
    B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. <i>Science</i>. AAAS. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>
  chicago: Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu,
    Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose.
    “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling
    Cell Shape.” <i>Science</i>. AAAS, 2026. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>.
  ieee: B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery
    into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392,
    no. 6795. AAAS, 2026.
  ista: Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL,
    Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. Science. 392(6795), eaea6343.
  mla: Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery
    into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392,
    no. 6795, eaea6343, AAAS, 2026, doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>.
  short: B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L.
    Weiss, F.K. Schur, M. Loose, Science 392 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-08-26T09:09:05Z
day: '16'
department:
- _id: MaLo
- _id: FlSc
- _id: GradSch
- _id: EM-Fac
doi: 10.1126/science.aea6343
ec_funded: 1
external_id:
  pmid:
  - '41990175'
intvolume: '       392'
issue: '6795'
language:
- iso: eng
month: '04'
oa_version: None
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: bd980d18-d553-11ed-ba76-ceaa645c97eb
  grant_number: '101076260'
  name: A molecular atlas of Actin filament IDentities in the cell motility machinery
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
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type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
