---
OA_place: publisher
OA_type: free access
_id: '23114'
article_number: e70847
article_processing_charge: No
article_type: editorial
author:
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
- first_name: Anne
  full_name: Nijs, Anne
  last_name: Nijs
citation:
  ama: Pieber B, Nijs A. The EuChemS division of organic chemistry and EurJOC - partners
    in advancing organic chemistry. <i>European Journal of Organic Chemistry</i>.
    2026. doi:<a href="https://doi.org/10.1002/ejoc.70847">10.1002/ejoc.70847</a>
  apa: Pieber, B., &#38; Nijs, A. (2026). The EuChemS division of organic chemistry
    and EurJOC - partners in advancing organic chemistry. <i>European Journal of Organic
    Chemistry</i>. Wiley. <a href="https://doi.org/10.1002/ejoc.70847">https://doi.org/10.1002/ejoc.70847</a>
  chicago: Pieber, Bartholomäus, and Anne Nijs. “The EuChemS Division of Organic Chemistry
    and EurJOC - Partners in Advancing Organic Chemistry.” <i>European Journal of
    Organic Chemistry</i>. Wiley, 2026. <a href="https://doi.org/10.1002/ejoc.70847">https://doi.org/10.1002/ejoc.70847</a>.
  ieee: B. Pieber and A. Nijs, “The EuChemS division of organic chemistry and EurJOC
    - partners in advancing organic chemistry,” <i>European Journal of Organic Chemistry</i>.
    Wiley, 2026.
  ista: Pieber B, Nijs A. 2026. The EuChemS division of organic chemistry and EurJOC
    - partners in advancing organic chemistry. European Journal of Organic Chemistry.,
    e70847.
  mla: Pieber, Bartholomäus, and Anne Nijs. “The EuChemS Division of Organic Chemistry
    and EurJOC - Partners in Advancing Organic Chemistry.” <i>European Journal of
    Organic Chemistry</i>, e70847, Wiley, 2026, doi:<a href="https://doi.org/10.1002/ejoc.70847">10.1002/ejoc.70847</a>.
  short: B. Pieber, A. Nijs, European Journal of Organic Chemistry (2026).
corr_author: '1'
date_created: 2026-10-12T12:10:22Z
date_published: 2026-09-21T00:00:00Z
date_updated: 2026-10-14T07:43:31Z
day: '21'
department:
- _id: BaPi
doi: 10.1002/ejoc.70847
fulldoi: https://doi.org/10.1002/ejoc.70847
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/ejoc.70847
month: '09'
oa: 1
oa_version: Published Version
publication: European Journal of Organic Chemistry
publication_identifier:
  eissn:
  - 1099-0690
  issn:
  - 1434-193X
publication_status: epub_ahead
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: The EuChemS division of organic chemistry and EurJOC - partners in advancing
  organic chemistry
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '23123'
abstract:
- lang: eng
  text: "How many points can be placed in an \U0001D45B × \U0001D45B grid sothat every
    (affine) line contains at most \U0001D458 points? Weprove that for \U0001D45B
    ⩾ \U0001D458 ⩾ 1037 the maximum number ofpoints is exactly \U0001D458\U0001D45B.
    Our proof builds on the recent workof Kovács, Nagy and Szabó (who proved an analogousresult
    when \U0001D458 is at least about √\U0001D45B log \U0001D45B), incorporat-ing
    ideas of Jain and Pham. Using the same approach,we also obtain new bounds for
    higher-dimensionalextensions of this problem"
acknowledgement: We would like to thank Huy Pham for insightful discussions about
  the proof approach, and wewould like to thank the anonymous referees for their careful
  reading and helpful comments. Bothauthors are supported by ERC Starting Grant “RANDSTRUCT”
  No. 101076777.Open Access funding provided by Institute of Science and Technology
  Austria.
article_number: e70510
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Aleksandr
  full_name: Grebennikov, Aleksandr
  id: 776468ec-50b0-11ef-861e-96ad19e894f3
  last_name: Grebennikov
- first_name: Matthew Alan
  full_name: Kwan, Matthew Alan
  id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3
  last_name: Kwan
  orcid: 0000-0002-4003-7567
citation:
  ama: Grebennikov A, Kwan MA. No‐(k+1)‐in‐line problem for large constant k. <i>Bulletin
    of the London Mathematical Society</i>. 2026;58(10). doi:<a href="https://doi.org/10.1112/blms.70510">10.1112/blms.70510</a>
  apa: Grebennikov, A., &#38; Kwan, M. A. (2026). No‐(k+1)‐in‐line problem for large
    constant k. <i>Bulletin of the London Mathematical Society</i>. Wiley. <a href="https://doi.org/10.1112/blms.70510">https://doi.org/10.1112/blms.70510</a>
  chicago: Grebennikov, Aleksandr, and Matthew Alan Kwan. “No‐(K+1)‐in‐line Problem
    for Large Constant K.” <i>Bulletin of the London Mathematical Society</i>. Wiley,
    2026. <a href="https://doi.org/10.1112/blms.70510">https://doi.org/10.1112/blms.70510</a>.
  ieee: A. Grebennikov and M. A. Kwan, “No‐(k+1)‐in‐line problem for large constant
    k,” <i>Bulletin of the London Mathematical Society</i>, vol. 58, no. 10. Wiley,
    2026.
  ista: Grebennikov A, Kwan MA. 2026. No‐(k+1)‐in‐line problem for large constant
    k. Bulletin of the London Mathematical Society. 58(10), e70510.
  mla: Grebennikov, Aleksandr, and Matthew Alan Kwan. “No‐(K+1)‐in‐line Problem for
    Large Constant K.” <i>Bulletin of the London Mathematical Society</i>, vol. 58,
    no. 10, e70510, Wiley, 2026, doi:<a href="https://doi.org/10.1112/blms.70510">10.1112/blms.70510</a>.
  short: A. Grebennikov, M.A. Kwan, Bulletin of the London Mathematical Society 58
    (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-10-12T13:57:47Z
date_published: 2026-10-01T00:00:00Z
date_updated: 2026-10-14T08:41:00Z
day: '01'
ddc:
- '510'
department:
- _id: MaKw
- _id: GradSch
doi: 10.1112/blms.70510
file:
- access_level: open_access
  checksum: cce830e3fc66174803b91103f5b88a29
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-14T08:37:16Z
  date_updated: 2026-10-14T08:37:16Z
  file_id: '23139'
  file_name: 2026_BulletinLondonMathSoc_Grebennikov.pdf
  file_size: 284851
  relation: main_file
  success: 1
file_date_updated: 2026-10-14T08:37:16Z
fulldoi: https://doi.org/10.1112/blms.70510
has_accepted_license: '1'
intvolume: '        58'
issue: '10'
language:
- iso: eng
mathsc:
- 05D40
- 52C10
- 52C35
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: bd95085b-d553-11ed-ba76-e55d3349be45
  grant_number: '101076777'
  name: Randomness and structure in combinatorics
publication: Bulletin of the London Mathematical Society
publication_identifier:
  eissn:
  - 1469-2120
  issn:
  - 0024-6093
publication_status: published
publisher: Wiley
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: No‐(k+1)‐in‐line problem for large constant k
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '23121'
abstract:
- lang: eng
  text: 'A widespread observation in molecular evolution is that X-linked genes evolve
    faster—and often adapt faster—than autosomal genes. Three main ideas have been
    put forward to explain “faster-X” adaptation. The first is that new beneficial
    mutations are typically partially recessive with respect to fitness, leading to
    more efficient selection in hemizygous males. The second is that sex differences
    in recombination, or sex differences in variance in reproductive success, enhance
    the effective population size on the X chromosome relative to autosomes. Both
    ideas have limitations: the first conflicts with theories of dominance, in which
    beneficial mutations are proposed to be partially dominant, while the second only
    applies to some taxa. Here we tested a third, newly-proposed theory, in which
    mutations with large “scaled phenotypic effects” (i.e., large effects relative
    to the distance to a phenotypic optimum) experience more positive selection on
    the X. Specifically, we used three proxies for scaled phenotypic effects—amino-acid
    dissimilarity, amino-acid conservation, and gene age—and estimated X and autosomal
    rates of adaptation of nonsynonymous mutations across effect-size classes. We
    did this in three lineages with a well-documented faster-X: Drosophila melanogaster,
    Mus musculus, and Homo sapiens. As expected, we found that large-effect mutations
    were more likely to be under purifying selection and less likely to be under positive
    selection than small-effect mutations. However, contrary to the new theory, faster-X
    adaptation was not enriched among large-effect mutations. Overall, our results
    highlight an unresolved gap between patterns of sex chromosome evolution and theories
    of dominance for fitness.'
article_number: evag259
article_processing_charge: Yes
article_type: original
author:
- first_name: Filip
  full_name: Ruzicka, Filip
  id: 347955dd-57b0-11ee-9095-c28bdd368f4b
  last_name: Ruzicka
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
biorxivid: 1
citation:
  ama: Ruzicka F, Vicoso B. Is faster-X adaptation due to large-effect mutations?
    An empirical test of a new theory. <i>Genome Biology and Evolution</i>. 2026.
    doi:<a href="https://doi.org/10.1093/gbe/evag259">10.1093/gbe/evag259</a>
  apa: Ruzicka, F., &#38; Vicoso, B. (2026). Is faster-X adaptation due to large-effect
    mutations? An empirical test of a new theory. <i>Genome Biology and Evolution</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/gbe/evag259">https://doi.org/10.1093/gbe/evag259</a>
  chicago: Ruzicka, Filip, and Beatriz Vicoso. “Is Faster-X Adaptation Due to Large-Effect
    Mutations? An Empirical Test of a New Theory.” <i>Genome Biology and Evolution</i>.
    Oxford University Press, 2026. <a href="https://doi.org/10.1093/gbe/evag259">https://doi.org/10.1093/gbe/evag259</a>.
  ieee: F. Ruzicka and B. Vicoso, “Is faster-X adaptation due to large-effect mutations?
    An empirical test of a new theory,” <i>Genome Biology and Evolution</i>. Oxford
    University Press, 2026.
  ista: Ruzicka F, Vicoso B. 2026. Is faster-X adaptation due to large-effect mutations?
    An empirical test of a new theory. Genome Biology and Evolution., evag259.
  mla: Ruzicka, Filip, and Beatriz Vicoso. “Is Faster-X Adaptation Due to Large-Effect
    Mutations? An Empirical Test of a New Theory.” <i>Genome Biology and Evolution</i>,
    evag259, Oxford University Press, 2026, doi:<a href="https://doi.org/10.1093/gbe/evag259">10.1093/gbe/evag259</a>.
  short: F. Ruzicka, B. Vicoso, Genome Biology and Evolution (2026).
corr_author: '1'
date_created: 2026-10-12T13:56:46Z
date_published: 2026-10-10T00:00:00Z
date_updated: 2026-10-14T08:17:09Z
day: '10'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evag259
external_id:
  biorxivid:
  - 10.64898/2026.02.06.704462
fulldoi: https://doi.org/10.1093/gbe/evag259
has_accepted_license: '1'
keyword:
- evolutionary biology
- population genetics
- sex chromosomes
- adaptation
- genetic divergence
- McDonald-Kreitman test
- Fisher’s geometric model
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/gbe/evag259
month: '10'
oa: 1
oa_version: Published Version
publication: Genome Biology and Evolution
publication_identifier:
  eissn:
  - 1759-6653
publication_status: epub_ahead
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Is faster-X adaptation due to large-effect mutations? An empirical test of
  a new theory
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '23128'
abstract:
- lang: eng
  text: 'Carbon fixed in source leaves is partitioned between local use and long-distance
    transport through the phloem to heterotrophic sinks such as roots. Here, we investigated
    how mild defects in sink phloem differentiation influence whole-plant growth using
    two Arabidopsis mutants: ops, which exhibits short roots with protophloem differentiation
    defects, and ops opl2, which displays even shorter roots with combined proto-
    and metaphloem differentiation defects. Carbon partitioning and phloem transport
    velocity were compromised in both mutants, with ops opl2 exhibiting stronger effects.
    Root growth responses to exogenous sucrose highlighted functional differences:
    only ops opl2 root growth was partially rescued, indicating additional limitations
    from compromised metaphloem function. Reciprocal grafting confirmed that root
    growth defects in both mutants are root autonomous. In contrast, source-limited
    starch mutants with short roots were rescued by sucrose supplementation or by
    grafting wild-type scions, highlighting that the growth limitation in the roots
    of phloem mutants is not solely due to carbon shortage. Impaired root phloem also
    restricted wild-type scion growth, revealing feedback from sink phloem integrity
    on source activity. Together, these findings show that sink phloem development
    supports sink function and mediates systemic feedback shaping whole-plant growth.
    Targeted modulation of sink phloem development could help optimize source–sink
    relations and improve crop performance.'
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Kai
  full_name: Bartusch, Kai
  id: 0c51b9f5-90c8-11f1-b4ef-9ad5d3d9a34a
  last_name: Bartusch
  orcid: 0000-0003-2708-5545
- first_name: Tina B
  full_name: Schreier, Tina B
  last_name: Schreier
- first_name: Michaela
  full_name: Fischer-Stettler, Michaela
  last_name: Fischer-Stettler
- first_name: Samuel C
  full_name: Zeeman, Samuel C
  last_name: Zeeman
- first_name: Elisabeth
  full_name: Truernit, Elisabeth
  last_name: Truernit
citation:
  ama: Bartusch K, Schreier TB, Fischer-Stettler M, Zeeman SC, Truernit E. Grafting
    reveals organ-autonomous and feedback roles of root phloem development in source–sink
    dynamics. <i>Journal of Experimental Botany</i>. 2026;77(8):2418-2428. doi:<a
    href="https://doi.org/10.1093/jxb/erag042">10.1093/jxb/erag042</a>
  apa: Bartusch, K., Schreier, T. B., Fischer-Stettler, M., Zeeman, S. C., &#38; Truernit,
    E. (2026). Grafting reveals organ-autonomous and feedback roles of root phloem
    development in source–sink dynamics. <i>Journal of Experimental Botany</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/jxb/erag042">https://doi.org/10.1093/jxb/erag042</a>
  chicago: Bartusch, Kai, Tina B Schreier, Michaela Fischer-Stettler, Samuel C Zeeman,
    and Elisabeth Truernit. “Grafting Reveals Organ-Autonomous and Feedback Roles
    of Root Phloem Development in Source–Sink Dynamics.” <i>Journal of Experimental
    Botany</i>. Oxford University Press, 2026. <a href="https://doi.org/10.1093/jxb/erag042">https://doi.org/10.1093/jxb/erag042</a>.
  ieee: K. Bartusch, T. B. Schreier, M. Fischer-Stettler, S. C. Zeeman, and E. Truernit,
    “Grafting reveals organ-autonomous and feedback roles of root phloem development
    in source–sink dynamics,” <i>Journal of Experimental Botany</i>, vol. 77, no.
    8. Oxford University Press, pp. 2418–2428, 2026.
  ista: Bartusch K, Schreier TB, Fischer-Stettler M, Zeeman SC, Truernit E. 2026.
    Grafting reveals organ-autonomous and feedback roles of root phloem development
    in source–sink dynamics. Journal of Experimental Botany. 77(8), 2418–2428.
  mla: Bartusch, Kai, et al. “Grafting Reveals Organ-Autonomous and Feedback Roles
    of Root Phloem Development in Source–Sink Dynamics.” <i>Journal of Experimental
    Botany</i>, vol. 77, no. 8, Oxford University Press, 2026, pp. 2418–28, doi:<a
    href="https://doi.org/10.1093/jxb/erag042">10.1093/jxb/erag042</a>.
  short: K. Bartusch, T.B. Schreier, M. Fischer-Stettler, S.C. Zeeman, E. Truernit,
    Journal of Experimental Botany 77 (2026) 2418–2428.
date_created: 2026-10-13T11:14:46Z
date_published: 2026-04-15T00:00:00Z
date_updated: 2026-10-14T09:01:45Z
day: '15'
ddc:
- '580'
doi: 10.1093/jxb/erag042
extern: '1'
external_id:
  pmid:
  - '41606772'
fulldoi: https://doi.org/10.1093/jxb/erag042
intvolume: '        77'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/jxb/erag042
month: '04'
oa: 1
oa_version: Published Version
page: 2418-2428
pmid: 1
publication: Journal of Experimental Botany
publication_identifier:
  eissn:
  - 1460-2431
  issn:
  - 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Grafting reveals organ-autonomous and feedback roles of root phloem development
  in source–sink dynamics
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 77
year: '2026'
...
---
OA_type: closed access
_id: '23126'
abstract:
- lang: eng
  text: Plant grafting is a powerful tool in research and agriculture, enabling the
    study of long-distance signaling and improving crop performance. Hypocotyl grafting
    in Arabidopsis thaliana has become a key method for investigating inter-tissue
    communication, root-to-shoot transport, and vascular regeneration. Here, we describe
    a high-throughput hypocotyl grafting protocol that consistently achieves success
    rates above 90% while minimizing complications, such as adventitious root formation,
    through an optimized hypocotyl cutting position. Our streamlined approach eliminates
    the need for silicone tubes and fine forceps, requiring only a standard scalpel
    for the cutting and joining procedure. With proper training, an experienced user
    can graft up to 1000 plants per day, facilitating large-scale experiments. Additionally,
    we present vascular connectivity assays using fluorescent dyes and the adjuvant
    Adigor to enable phloem and xylem transport analysis across the graft junction
    without the need for wounding. By simplifying the grafting process while maintaining
    high efficiency, our protocol makes Arabidopsis grafting more accessible and scalable,
    facilitating research on long-distance molecular transport, vascular development,
    and plant biotechnology applications.
alternative_title:
- Methods in Molecular Biology
article_processing_charge: No
author:
- first_name: Kai
  full_name: Bartusch, Kai
  id: 0c51b9f5-90c8-11f1-b4ef-9ad5d3d9a34a
  last_name: Bartusch
  orcid: 0000-0003-2708-5545
- first_name: Elisabeth
  full_name: Truernit, Elisabeth
  last_name: Truernit
citation:
  ama: 'Bartusch K, Truernit E. High-Throughput Hypocotyl Grafting and Vascular Reconnection
    Assessment in Arabidopsis Seedlings. In: Liesche J, Sevanto S, eds. <i>Phloem</i>.
    2nd ed. MIMB. New York, NY: Springer; 2026:431-448. doi:<a href="https://doi.org/10.1007/978-1-0716-5488-0_33">10.1007/978-1-0716-5488-0_33</a>'
  apa: 'Bartusch, K., &#38; Truernit, E. (2026). High-Throughput Hypocotyl Grafting
    and Vascular Reconnection Assessment in Arabidopsis Seedlings. In J. Liesche &#38;
    S. Sevanto (Eds.), <i>Phloem</i> (2nd ed., pp. 431–448). New York, NY: Springer.
    <a href="https://doi.org/10.1007/978-1-0716-5488-0_33">https://doi.org/10.1007/978-1-0716-5488-0_33</a>'
  chicago: 'Bartusch, Kai, and Elisabeth Truernit. “High-Throughput Hypocotyl Grafting
    and Vascular Reconnection Assessment in Arabidopsis Seedlings.” In <i>Phloem</i>,
    edited by Johannes Liesche and Sanna Sevanto, 2nd ed., 431–48. MIMB. New York,
    NY: Springer, 2026. <a href="https://doi.org/10.1007/978-1-0716-5488-0_33">https://doi.org/10.1007/978-1-0716-5488-0_33</a>.'
  ieee: 'K. Bartusch and E. Truernit, “High-Throughput Hypocotyl Grafting and Vascular
    Reconnection Assessment in Arabidopsis Seedlings,” in <i>Phloem</i>, 2nd ed.,
    J. Liesche and S. Sevanto, Eds. New York, NY: Springer, 2026, pp. 431–448.'
  ista: 'Bartusch K, Truernit E. 2026.High-Throughput Hypocotyl Grafting and Vascular
    Reconnection Assessment in Arabidopsis Seedlings. In: Phloem. Methods in Molecular
    Biology, , 431–448.'
  mla: Bartusch, Kai, and Elisabeth Truernit. “High-Throughput Hypocotyl Grafting
    and Vascular Reconnection Assessment in Arabidopsis Seedlings.” <i>Phloem</i>,
    edited by Johannes Liesche and Sanna Sevanto, 2nd ed., Springer, 2026, pp. 431–48,
    doi:<a href="https://doi.org/10.1007/978-1-0716-5488-0_33">10.1007/978-1-0716-5488-0_33</a>.
  short: K. Bartusch, E. Truernit, in:, J. Liesche, S. Sevanto (Eds.), Phloem, 2nd
    ed., Springer, New York, NY, 2026, pp. 431–448.
date_created: 2026-10-13T11:14:23Z
date_published: 2026-09-03T00:00:00Z
date_updated: 2026-10-14T08:58:03Z
day: '03'
doi: 10.1007/978-1-0716-5488-0_33
edition: '2'
editor:
- first_name: Johannes
  full_name: Liesche, Johannes
  last_name: Liesche
- first_name: Sanna
  full_name: Sevanto, Sanna
  last_name: Sevanto
extern: '1'
external_id:
  pmid:
  - '42681141'
fulldoi: https://doi.org/10.1007/978-1-0716-5488-0_33
language:
- iso: eng
month: '09'
oa_version: None
page: 431-448
place: New York, NY
pmid: 1
publication: Phloem
publication_identifier:
  eisbn:
  - '9781071654880'
  eissn:
  - 1940-6029
  isbn:
  - '9781071654873'
  issn:
  - 1064-3745
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
series_title: MIMB
status: public
title: High-Throughput Hypocotyl Grafting and Vascular Reconnection Assessment in
  Arabidopsis Seedlings
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
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abstract:
- lang: eng
  text: "Among the set of hypersurfaces of degree d and dimension  defined by the
    vanishing\r\nof a homogeneous polynomial with coefficients in the set {−1, +1},
    we investigate the\r\nprobability that a hypersurface contains a rational point
    as d and  tend to ∞."
acknowledgement: "The authors are very grateful to Pierre Le Boudec, whose contributions
  would have merited coauthorship. At his request, however, he is not listed as a
  co-author, since he has chosen to pursue\r\na career outside academia. T.B. was
  supported by a grant from the IAS School of Mathematics\r\nand a FWF grant (DOI
  10.55776/P36278). W.S. was supported by NSF grant DMS-2502029 and\r\na Sloan Research
  Fellowship."
article_number: haag037
article_processing_charge: Yes (via OA deal)
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author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Will
  full_name: Sawin, Will
  last_name: Sawin
citation:
  ama: Browning TD, Sawin W. Random diophantine equations of large degree. <i>The
    Quarterly Journal of Mathematics</i>. 2026. doi:<a href="https://doi.org/10.1093/qmath/haag037">10.1093/qmath/haag037</a>
  apa: Browning, T. D., &#38; Sawin, W. (2026). Random diophantine equations of large
    degree. <i>The Quarterly Journal of Mathematics</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/qmath/haag037">https://doi.org/10.1093/qmath/haag037</a>
  chicago: Browning, Timothy D, and Will Sawin. “Random Diophantine Equations of Large
    Degree.” <i>The Quarterly Journal of Mathematics</i>. Oxford University Press,
    2026. <a href="https://doi.org/10.1093/qmath/haag037">https://doi.org/10.1093/qmath/haag037</a>.
  ieee: T. D. Browning and W. Sawin, “Random diophantine equations of large degree,”
    <i>The Quarterly Journal of Mathematics</i>. Oxford University Press, 2026.
  ista: Browning TD, Sawin W. 2026. Random diophantine equations of large degree.
    The Quarterly Journal of Mathematics., haag037.
  mla: Browning, Timothy D., and Will Sawin. “Random Diophantine Equations of Large
    Degree.” <i>The Quarterly Journal of Mathematics</i>, haag037, Oxford University
    Press, 2026, doi:<a href="https://doi.org/10.1093/qmath/haag037">10.1093/qmath/haag037</a>.
  short: T.D. Browning, W. Sawin, The Quarterly Journal of Mathematics (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-10-12T13:58:16Z
date_published: 2026-10-06T00:00:00Z
date_updated: 2026-10-14T08:49:05Z
day: '06'
ddc:
- '500'
department:
- _id: TiBr
doi: 10.1093/qmath/haag037
external_id:
  arxiv:
  - '2510.26191'
fulldoi: https://doi.org/10.1093/qmath/haag037
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
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  url: https://doi.org/10.1093/qmath/haag037
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: bd8a4fdc-d553-11ed-ba76-80a0167441a3
  grant_number: P36278
  name: Rational curves via function field analytic number theory
publication: The Quarterly Journal of Mathematics
publication_identifier:
  eissn:
  - 1464-3847
  issn:
  - 0033-5606
publication_status: epub_ahead
publisher: Oxford University Press
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: Random diophantine equations of large degree
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
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  last_name: Bartusch
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citation:
  ama: Bartusch K. New molecular insights into phloem development and its role in
    plant growth. 2026. doi:<a href="https://doi.org/10.3929/ETHZ-C-000797253">10.3929/ETHZ-C-000797253</a>
  apa: Bartusch, K. (2026). <i>New molecular insights into phloem development and
    its role in plant growth</i>. ETH Zürich. <a href="https://doi.org/10.3929/ETHZ-C-000797253">https://doi.org/10.3929/ETHZ-C-000797253</a>
  chicago: Bartusch, Kai. “New Molecular Insights into Phloem Development and Its
    Role in Plant Growth.” ETH Zürich, 2026. <a href="https://doi.org/10.3929/ETHZ-C-000797253">https://doi.org/10.3929/ETHZ-C-000797253</a>.
  ieee: K. Bartusch, “New molecular insights into phloem development and its role
    in plant growth,” ETH Zürich, 2026.
  ista: Bartusch K. 2026. New molecular insights into phloem development and its role
    in plant growth. ETH Zürich.
  mla: Bartusch, Kai. <i>New Molecular Insights into Phloem Development and Its Role
    in Plant Growth</i>. ETH Zürich, 2026, doi:<a href="https://doi.org/10.3929/ETHZ-C-000797253">10.3929/ETHZ-C-000797253</a>.
  short: K. Bartusch, New Molecular Insights into Phloem Development and Its Role
    in Plant Growth, ETH Zürich, 2026.
date_created: 2026-10-13T11:14:35Z
date_published: 2026-03-13T00:00:00Z
date_updated: 2026-10-14T12:35:51Z
day: '13'
degree_awarded: PhD
doi: 10.3929/ETHZ-C-000797253
doi_confirm: '1'
extern: '1'
fulldoi: https://doi.org/10.3929/ETHZ-C-000797253
language:
- iso: eng
month: '03'
oa_version: None
publication_status: published
publisher: ETH Zürich
status: public
title: New molecular insights into phloem development and its role in plant growth
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
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alternative_title:
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author:
- first_name: Anastasiia
  full_name: Teplova, Anastasiia
  id: e3736151-106c-11ec-b916-c2558e2762c6
  last_name: Teplova
citation:
  ama: 'Teplova A. Chasing the elusive: Investigating nucleotide cyclase activity
    in gibberellin and strigolactone signalling; Cellular mechanisms of gravity sensing
    and response in roots. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22984">10.15479/AT-ISTA-22984</a>'
  apa: 'Teplova, A. (2026). <i>Chasing the elusive: Investigating nucleotide cyclase
    activity in gibberellin and strigolactone signalling; Cellular mechanisms of gravity
    sensing and response in roots</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-22984">https://doi.org/10.15479/AT-ISTA-22984</a>'
  chicago: 'Teplova, Anastasiia. “Chasing the Elusive: Investigating Nucleotide Cyclase
    Activity in Gibberellin and Strigolactone Signalling; Cellular Mechanisms of Gravity
    Sensing and Response in Roots.” Institute of Science and Technology Austria, 2026.
    <a href="https://doi.org/10.15479/AT-ISTA-22984">https://doi.org/10.15479/AT-ISTA-22984</a>.'
  ieee: 'A. Teplova, “Chasing the elusive: Investigating nucleotide cyclase activity
    in gibberellin and strigolactone signalling; Cellular mechanisms of gravity sensing
    and response in roots,” Institute of Science and Technology Austria, 2026.'
  ista: 'Teplova A. 2026. Chasing the elusive: Investigating nucleotide cyclase activity
    in gibberellin and strigolactone signalling; Cellular mechanisms of gravity sensing
    and response in roots. Institute of Science and Technology Austria.'
  mla: 'Teplova, Anastasiia. <i>Chasing the Elusive: Investigating Nucleotide Cyclase
    Activity in Gibberellin and Strigolactone Signalling; Cellular Mechanisms of Gravity
    Sensing and Response in Roots</i>. Institute of Science and Technology Austria,
    2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22984">10.15479/AT-ISTA-22984</a>.'
  short: 'A. Teplova, Chasing the Elusive: Investigating Nucleotide Cyclase Activity
    in Gibberellin and Strigolactone Signalling; Cellular Mechanisms of Gravity Sensing
    and Response in Roots, Institute of Science and Technology Austria, 2026.'
corr_author: '1'
date_created: 2026-09-23T15:29:42Z
date_published: 2026-09-23T00:00:00Z
date_updated: 2026-10-15T08:30:03Z
day: '23'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JiFr
doi: 10.15479/AT-ISTA-22984
doi_confirm: '1'
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publisher: Institute of Science and Technology Austria
related_material:
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    status: public
status: public
supervisor:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
title: 'Chasing the elusive: Investigating nucleotide cyclase activity in gibberellin
  and strigolactone signalling; Cellular mechanisms of gravity sensing and response
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type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
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...
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abstract:
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  text: "We study the computational aspects of the two central solution concepts of
    stochastic games\r\nplayed on finite graphs for an infinite number of steps: the
    value in two-player zero-sum\r\ngames, and Nash equilibria in multi-player games.
    In both settings, exact solutions are in\r\ntractable. Fortwo-playerzero-sumconcurrentstochasticgames,valuescanbeirrational,and\r\nthe
    associated decision problem is SQRT-SUM hard. For multi-player turn-based stochastic\r\ngames,theequilibriumprobabilitiescanbeirrational,anddecidingtheconstrainedexistence\r\nof
    a Nash equilibrium is undecidable in the presence of memory, and ∃R-complete when
    the\r\nplayers are restricted to stationary strategies. Hence, in both settings,
    the natural computational problem is the approximation of the solution within
    an arbitrary additive error. In\r\nthis thesis, we present improved complexity
    results and algorithms for such approximation\r\nproblems.\r\nThe first part of
    the thesis considers two-player zero-sum concurrent stochastic games\r\nwith two
    classic objectives: (a) stateful-discounted objectives, which are similar to the
    classic\r\ndiscounted-sum objectives, but states are associated with different
    discount factors rather\r\nthan a single discount factor; and (b) parity objectives,
    which are a canonical representation\r\nfor ω-regular objectives. For stateful-discounted
    objectives, given an ordering of the discount\r\nfactors, the limit value is the
    limit of the value of the stateful-discounted objectives, as\r\nthe discount factors
    approach zero according to the given order. The value-approximation\r\nproblem
    is known to be in EXPSPACE for the limit value of stateful-discounted objectives
    and\r\nin PSPACEforparityobjectives,andthebest-knownalgorithmsforbothproblemsareatleast\r\nexponential
    time, with an exponential dependence on the number of states and actions. Our\r\nmain
    results for the value-approximation problem for the limit value of stateful-discounted\r\nobjectives
    and parity objectives areas follows: (a)we establish TFNPNP complexity; and (b)we\r\npresent
    algorithms that improve the dependency on the number of actions in the exponent\r\nfrom
    linear to logarithmic. In particular, if the number of states is constant, our
    algorithms\r\nrun in polynomial time.\r\nThe second part of the thesis considers
    multi-player turn-based stochastic games with\r\nterminal payoffs, where the players
    are restricted to stationary strategies. We study the\r\napproximate constrained
    existence problem of Nash equilibria: given a game that has a Nash\r\nequilibrium
    in which the payoff of every player lies in a given interval, compute a strategy\r\nprofile
    that is an ε-Nash equilibrium and that satisfies the same constraints up to an
    additive\r\nerror ε. Our main results are as follows: (a) we present an FNPNP
    algorithm for the problem;\r\nand(b)we establish that its decision version is
    NP-hard, already with two players. For the\r\nupperbound,weshowthatifaconstrainedNashequilibriumexists,thenthereexists
    one\r\nin which the non-zero probabilities are at least an inverse of a double-exponential
    in the\r\ni\r\ninput size, and that such a strategy profile can be represented,
    up to an additive error ε, with\r\nfloating-point numbers of polynomial size.
    We complement the upper bound with a lower\r\nbound on this approach: we present
    a game with only five players in which every constrained\r\nNash equilibrium requires
    double-exponentially small probabilities.\r\nThe two parts share a common technical
    toolkit: bounds on solutions of systems of\r\npolynomial inequalities that arise
    from real algebraic geometry, the floating-point representation of doubly-exponentially
    small numbers, and guess-and-verify procedures that resolve\r\nsingle-player games
    with an NP oracle."
acknowledgement: "The research reported in Part I was partially supported by the European
  Research\r\nCouncil (ERC) Consolidator Grant 863818 (ForM-SMArt), by the Austrian
  Science Fund\r\n(FWF) 10.55776/COE12, and by the French Agence Nationale de la Recherche
  (ANR) grant\r\nANR-21-CE40-0020 (CONVERGENCE project). The research reported in
  Part II is a part of\r\nproject VAMOS, which has received funding from the European
  Research Council (ERC) under\r\ngrant agreement No.101020093."
alternative_title:
- ISTA Master’s Thesis
article_processing_charge: No
author:
- first_name: Ali
  full_name: Asadi, Ali
  id: 02d96aae-000e-11ec-b801-cadd0a5eefbb
  last_name: Asadi
citation:
  ama: 'Asadi A. Approximation of values and equilibria in stochastic games: Complexity
    and algorithms. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-23079">10.15479/AT-ISTA-23079</a>'
  apa: 'Asadi, A. (2026). <i>Approximation of values and equilibria in stochastic
    games: Complexity and algorithms</i>. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT-ISTA-23079">https://doi.org/10.15479/AT-ISTA-23079</a>'
  chicago: 'Asadi, Ali. “Approximation of Values and Equilibria in Stochastic Games:
    Complexity and Algorithms.” Institute of Science and Technology Austria, 2026.
    <a href="https://doi.org/10.15479/AT-ISTA-23079">https://doi.org/10.15479/AT-ISTA-23079</a>.'
  ieee: 'A. Asadi, “Approximation of values and equilibria in stochastic games: Complexity
    and algorithms,” Institute of Science and Technology Austria, 2026.'
  ista: 'Asadi A. 2026. Approximation of values and equilibria in stochastic games:
    Complexity and algorithms. Institute of Science and Technology Austria.'
  mla: 'Asadi, Ali. <i>Approximation of Values and Equilibria in Stochastic Games:
    Complexity and Algorithms</i>. Institute of Science and Technology Austria, 2026,
    doi:<a href="https://doi.org/10.15479/AT-ISTA-23079">10.15479/AT-ISTA-23079</a>.'
  short: 'A. Asadi, Approximation of Values and Equilibria in Stochastic Games: Complexity
    and Algorithms, Institute of Science and Technology Austria, 2026.'
corr_author: '1'
date_created: 2026-10-08T09:07:53Z
date_published: 2026-10-09T00:00:00Z
date_updated: 2026-10-16T08:00:45Z
day: '09'
ddc:
- '000'
degree_awarded: MS
department:
- _id: GradSch
- _id: KrCh
doi: 10.15479/AT-ISTA-23079
doi_confirm: '1'
ec_funded: 1
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month: '10'
oa: 1
oa_version: Published Version
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project:
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  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 4029cfc7-b034-11f1-9e55-88ab2ff3b6ee
  grant_number: COE12
  name: Bilateral Artificial Intelligence (Chatterjee)
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication_identifier:
  issn:
  - 2791-4585
publication_status: published
publisher: Institute of Science and Technology Austria
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status: public
supervisor:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
title: 'Approximation of values and equilibria in stochastic games: Complexity and
  algorithms'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
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---
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acknowledgement: 'This thesis and the publications within, were financially supported
  by the Institute of Science and Technology Austria and the Werner Siemens Foundation
  under the project “High Thermoelectric Materials: The Werner Siemens Laboratory
  for the High Throughput Discovery of Semiconductors for Waste Heat Recovery”.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Christine
  full_name: Fiedler, Christine
  id: bd3fceba-dc74-11ea-a0a7-c17f71817366
  last_name: Fiedler
citation:
  ama: Fiedler C. Mechanistic insight into solution-processed p-type tin chalcogenides
    as a basis for designing their n-type analogs. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22626">10.15479/AT-ISTA-22626</a>
  apa: Fiedler, C. (2026). <i>Mechanistic insight into solution-processed p-type tin
    chalcogenides as a basis for designing their n-type analogs</i>. Institute of
    Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22626">https://doi.org/10.15479/AT-ISTA-22626</a>
  chicago: Fiedler, Christine. “Mechanistic Insight into Solution-Processed p-Type
    Tin Chalcogenides as a Basis for Designing Their n-Type Analogs.” Institute of
    Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22626">https://doi.org/10.15479/AT-ISTA-22626</a>.
  ieee: C. Fiedler, “Mechanistic insight into solution-processed p-type tin chalcogenides
    as a basis for designing their n-type analogs,” Institute of Science and Technology
    Austria, 2026.
  ista: Fiedler C. 2026. Mechanistic insight into solution-processed p-type tin chalcogenides
    as a basis for designing their n-type analogs. Institute of Science and Technology
    Austria.
  mla: Fiedler, Christine. <i>Mechanistic Insight into Solution-Processed p-Type Tin
    Chalcogenides as a Basis for Designing Their n-Type Analogs</i>. Institute of
    Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22626">10.15479/AT-ISTA-22626</a>.
  short: C. Fiedler, Mechanistic Insight into Solution-Processed p-Type Tin Chalcogenides
    as a Basis for Designing Their n-Type Analogs, Institute of Science and Technology
    Austria, 2026.
corr_author: '1'
date_created: 2026-08-03T07:55:16Z
date_published: 2026-08-05T00:00:00Z
date_updated: 2026-10-16T09:30:26Z
day: '05'
ddc:
- '540'
- '546'
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaIb
doi: 10.15479/AT-ISTA-22626
doi_confirm: '1'
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month: '08'
oa_version: Published Version
page: '141'
project:
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  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication_identifier:
  isbn:
  - 978-3-99078-086-2
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
  - id: '17124'
    relation: part_of_dissertation
    status: public
  - id: '17052'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
title: Mechanistic insight into solution-processed p-type tin chalcogenides as a basis
  for designing their n-type analogs
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
_id: '22017'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Tobias
  full_name: Kleinhanns, Tobias
  id: 8BD9DE16-AB3C-11E9-9C8C-2A03E6697425
  last_name: Kleinhanns
  orcid: 0000-0003-1537-7436
citation:
  ama: Kleinhanns T. Unraveling the origin and evolution of defects to enable advanced
    thermoelectric performance. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22017">10.15479/AT-ISTA-22017</a>
  apa: Kleinhanns, T. (2026). <i>Unraveling the origin and evolution of defects to
    enable advanced thermoelectric performance</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT-ISTA-22017">https://doi.org/10.15479/AT-ISTA-22017</a>
  chicago: Kleinhanns, Tobias. “Unraveling the Origin and Evolution of Defects to
    Enable Advanced Thermoelectric Performance.” Institute of Science and Technology
    Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22017">https://doi.org/10.15479/AT-ISTA-22017</a>.
  ieee: T. Kleinhanns, “Unraveling the origin and evolution of defects to enable advanced
    thermoelectric performance,” Institute of Science and Technology Austria, 2026.
  ista: Kleinhanns T. 2026. Unraveling the origin and evolution of defects to enable
    advanced thermoelectric performance. Institute of Science and Technology Austria.
  mla: Kleinhanns, Tobias. <i>Unraveling the Origin and Evolution of Defects to Enable
    Advanced Thermoelectric Performance</i>. Institute of Science and Technology Austria,
    2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22017">10.15479/AT-ISTA-22017</a>.
  short: T. Kleinhanns, Unraveling the Origin and Evolution of Defects to Enable Advanced
    Thermoelectric Performance, Institute of Science and Technology Austria, 2026.
corr_author: '1'
das_tickbox: '1'
date_created: 2026-06-18T08:00:03Z
date_published: 2026-06-18T00:00:00Z
date_updated: 2026-10-16T10:07:25Z
day: '18'
ddc:
- '546'
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaIb
doi: 10.15479/AT-ISTA-22017
doi_confirm: '1'
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language:
- iso: eng
month: '06'
oa_version: Published Version
page: '59'
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- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication_identifier:
  isbn:
  - 978-3-99078-081-7
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
    status: public
  - id: '15182'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
title: Unraveling the origin and evolution of defects to enable advanced thermoelectric
  performance
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
_id: '22664'
abstract:
- lang: eng
  text: "The widespread adoption of apps like Whatsapp and Signal has translated into
    billions of people all around the world communicating on a regular basis by making
    use of services that offer end-to-end encryption and even provide security guarantees
    when a user's device is compromised.\r\n\r\nThis was made possible by the introduction
    of the Double Ratchet Algorithm~\\cite{double_ratchet}, which was designed for
    a setting where communication takes place between two parties.\r\nHowever, in
    practice, many apps offer the possibility of creating groups.\r\nThe protocols
    they use to secure communication are inefficient for large group which has the
    undesireable consequence that the aforementioned apps have established limits
    on the group size of roughly 1000 users.\r\nThis has motivated the introduction
    of the Messaging Layer Security (MLS) standard~\\cite{rfc9420} by the IETF which
    is based on a primitive called Continuous Group Key Agreement (CGKA)~\\cite{C:ACDT20}.\r\n\r\nThis
    primitive allows a group of users to maintain a shared secret key that is frequently
    rotated by the group members in order to change group membership, achieve forward
    secrecy (FS) and post compromise security (PCS).\r\nMost protocols are based on
    binary trees where the nodes are associated to a pair formed by public key and
    a secret key.\r\nEach leaf corresponds to one of the group members and a user
    knows the secret keys associated to nodes along the path from their leaf to the
    root.\r\nWhen a user wants to update their key material they have to change $
    \\log(N) $ many keys.\r\nThis requires uploading $ \\log(N) $ many ciphertexts
    to communicate the new keys to the rest of the group members in a way that respects
    the tree structure.\r\n\r\nIn this thesis we study how much communication between
    group members is required in order to add and remove users from a group as well
    as in order to provide PCS when we consider CGKAs built using standard cryptographic
    primitives like pseudo-random functions and public-key encryption. Furthermore,
    we also consider the case of MLS and provide the first lower bound showing that
    its communication complexity is much worse than previously believed, i.e., it
    is very far from $ \\log(N) $.\r\nFinally, we also propose a variant of MLS which
    provably achieves the same security properties with a much lower communication
    cost."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Miguel
  full_name: Cueto Noval, Miguel
  id: ffc563a3-f6e0-11ea-865d-e3cce03d17cc
  last_name: Cueto Noval
  orcid: 0000-0002-2505-4246
citation:
  ama: Cueto Noval M. Towards efficient secure group messaging. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22664">10.15479/AT-ISTA-22664</a>
  apa: Cueto Noval, M. (2026). <i>Towards efficient secure group messaging</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22664">https://doi.org/10.15479/AT-ISTA-22664</a>
  chicago: Cueto Noval, Miguel. “Towards Efficient Secure Group Messaging.” Institute
    of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22664">https://doi.org/10.15479/AT-ISTA-22664</a>.
  ieee: M. Cueto Noval, “Towards efficient secure group messaging,” Institute of Science
    and Technology Austria, 2026.
  ista: Cueto Noval M. 2026. Towards efficient secure group messaging. Institute of
    Science and Technology Austria.
  mla: Cueto Noval, Miguel. <i>Towards Efficient Secure Group Messaging</i>. Institute
    of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22664">10.15479/AT-ISTA-22664</a>.
  short: M. Cueto Noval, Towards Efficient Secure Group Messaging, Institute of Science
    and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-08-10T10:18:35Z
date_published: 2026-08-10T00:00:00Z
date_updated: 2026-10-16T10:14:40Z
day: '10'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: KrPi
doi: 10.15479/AT-ISTA-22664
doi_confirm: '1'
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file_date_updated: 2026-08-19T11:36:46Z
fulldoi: https://doi.org/10.15479/AT-ISTA-22664
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: '187'
publication_identifier:
  isbn:
  - ' 978-3-99078-087-9'
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: part_of_dissertation
    status: public
  - id: '14691'
    relation: part_of_dissertation
    status: public
  - id: '18702'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
title: Towards efficient secure group messaging
tmp:
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  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
_id: '22857'
abstract:
- lang: eng
  text: "Artificial intelligence and machine learning have undergone an unprecedented
    evolution in the past decade, motivating a research effort toward a theory able
    to capture the qualitative behavior of large-scale neural systems. A central puzzle
    has been the clear benefit of scaling architecture size and overfitting the training
    set in supervised learning tasks. This evidence, in apparent contradiction with
    classical statistical learning theory, pushed researchers to develop a new theory
    capturing the interplay between the algorithmic and architectural bias of training
    and the specific target function, differently from previous methods rooted in
    uniform stability.\r\nThis approach has enabled a grounded understanding of novel
    learning regimes, typically through formal limits where the number of training
    samples $n$, data dimensions $d$, and model parameters $p$ grow to infinity at
    different rates. \\\\\r\nIn this thesis, we follow this approach, focusing on
    the trustworthiness of high-dimensional models: properties that are difficult
    to control during training or deployment and often emerge under unpredictable
    or adversarial conditions. In such settings, it is crucial to formally ensure
    a priori the reliability of machine learning systems.\r\nFirst, we study data
    memorization, both as label fitting and as the storage of private information
    about training samples in trained parameters. We prove that $p = \\Omega(n)$ parameters
    are sufficient for a deep neural network to memorize a generic set of labels,
    and for a model to memorize spurious features across training data. We then give
    evidence that $p = \\Omega(dn)$ parameters are instead necessary for an adversary
    to reconstruct the full training set from the trained parameters.\r\nSecond, we
    study robustness, both to adversarial perturbations and to distribution shift.
    We first prove that $p = \\Omega(dn)$ parameters can be sufficient for a class
    of neural networks to overfit the training data while guaranteeing robustness
    to adversarial perturbations. Then, we focus on spurious correlations learning
    in high-dimensional regression, studying the effect of the ridge regularization
    parameter in the proportional regime $n = \\Theta(d)$, and connecting it via an
    equivalence argument to the role of over-parameterization $p = \\Omega(n)$ in
    neural networks. We also investigate the architectural bias of attention-based
    networks, showing that they are sensitive to the replacement of individual words
    in an embedded sentence, allowing them to generalize on sentences where the contextual
    meaning depends on one or few words.\r\nFinally, we study differentially private
    optimization in high-dimensional regimes. We prove that standard private gradient
    methods do not suffer in the over-parameterized regime $p = \\Omega(n)$, challenging
    the current wisdom based on stability-derived generalization bounds. We then consider
    linear regression in the proportional regime $n = \\Theta(d)$, showing that standard
    private gradient descent can achieve optimal rates under appropriate hyper-parameter
    scaling, such as sufficiently small gradient clipping constants, whose role is
    still debated in practice."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "This project was partially supported by the 2019 Lopez-Loreta prize,\r\nthe
  European Union (ERC, INF2\r\n, project number 101161364), the Austrian Science Fund\r\n(FWF)
  10.55776/COE12, and a Google PhD fellowship in machine intelligence. Furthermore,\r\nthe
  candidate acknowledges the support from the Scientific Service Units of the Institute
  of\r\nScience and Technology Austria through resources provided by Scientific Computing."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Simone
  full_name: Bombari, Simone
  id: ca726dda-de17-11ea-bc14-f9da834f63aa
  last_name: Bombari
citation:
  ama: Bombari S. Trustworthy machine learning in high dimensions. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-22857">10.15479/AT-ISTA-22857</a>
  apa: Bombari, S. (2026). <i>Trustworthy machine learning in high dimensions</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-22857">https://doi.org/10.15479/AT-ISTA-22857</a>
  chicago: Bombari, Simone. “Trustworthy Machine Learning in High Dimensions.” Institute
    of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-22857">https://doi.org/10.15479/AT-ISTA-22857</a>.
  ieee: S. Bombari, “Trustworthy machine learning in high dimensions,” Institute of
    Science and Technology Austria, 2026.
  ista: Bombari S. 2026. Trustworthy machine learning in high dimensions. Institute
    of Science and Technology Austria.
  mla: Bombari, Simone. <i>Trustworthy Machine Learning in High Dimensions</i>. Institute
    of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-22857">10.15479/AT-ISTA-22857</a>.
  short: S. Bombari, Trustworthy Machine Learning in High Dimensions, Institute of
    Science and Technology Austria, 2026.
corr_author: '1'
das_tickbox: '0'
date_created: 2026-09-08T13:40:08Z
date_published: 2026-09-08T00:00:00Z
date_updated: 2026-10-16T10:42:36Z
day: '08'
ddc:
- '519'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MaMo
doi: 10.15479/AT-ISTA-22857
doi_confirm: '1'
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file_date_updated: 2026-09-10T10:03:48Z
fulldoi: https://doi.org/10.15479/AT-ISTA-22857
has_accepted_license: '1'
keyword:
- machine learning
- high-dimensional statistics
- deep learning theory
- privacy
- memorization
- robustness
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '446'
project:
- _id: 92099302-16d5-11f0-9cad-f9a785f54fbd
  name: 'Trustworthy Deep Learning Theory: Private Over-Parameterized Models and Robust
    LLMs'
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
  grant_number: '101161364'
  name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
- _id: 74caaef7-b034-11f1-8f2d-e0e993bb422e
  grant_number: COE12
  name: Bilateral Artificial Intelligence (Mondelli)
publication_identifier:
  isbn:
  - 978-3-99078-091-6
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '12537'
    relation: part_of_dissertation
    status: public
  - id: '21324'
    relation: part_of_dissertation
    status: public
  - id: '22894'
    relation: part_of_dissertation
    status: public
  - id: '19627'
    relation: part_of_dissertation
    status: public
  - id: '12859'
    relation: part_of_dissertation
    status: public
  - id: '18973'
    relation: part_of_dissertation
    status: public
  - id: '18972'
    relation: part_of_dissertation
    status: public
researchdata_availability: no
status: public
supervisor:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
supplementarymaterial: no
title: Trustworthy machine learning in high dimensions
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '23043'
abstract:
- lang: eng
  text: Mendelian randomization, the standard instrument variable causal-inference
    approach for genomics, can be severely biased by inadequate selection of appropriate
    instrument variables and horizontal pleiotropy. We introduce Causal Inference
    GWAS, a graphical approach that selects genetic instruments from summary statistics
    controlling for linkage and pleiotropy, accommodates rare variants and binary
    outcomes, distinguishes direct from indirect risk factors in high dimensions,
    and flags latent confounding. Applied to 9 risk factors, 4 metabolic disease outcomes,
    and 8.4M variants across 458,747 UK Biobank individuals, our method runs in 20
    minutes, identifying only 696 genome-wide valid instruments. We replicate nearly
    all previously reported risk factor-outcome paths, but find that most are indistinguishable
    from unmeasured confounding. This suggests robust biobank causal inference will
    require longitudinal and family data to resolve temporal precedence from reverse
    causation. Our approach offers a principled first step toward screening genuine
    causal signal from phenotypic correlation in biobank data.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank Zoltan Kutalik andmembers of the Robinson group at ISTA
  for\r\ntheir comments, which improved this manuscript. We would like to\r\nacknowledge
  the participants and investigators of the UK Biobank study.\r\nHigh-performance
  computing was supported by the Scientific Service\r\nUnits (SSU) of IST Austria
  through resources provided by Scientific\r\nComputing (SciComp). This work was funded
  by a research collaboration agreement between\r\nBoehringer Ingelheim and the research
  group of MRR at the Institute of\r\nScience and Technology Austria. Additional funding
  was also provided\r\nby an SNSF Eccellenza Grant to MRR (PCEGP3-181181), and by
  core\r\nfunding from the Institute of Science and Technology Austria. MB was\r\nfunded
  by the National Science Center Poland grant SONATINA UMO-\r\n2021/40/C/NZ2/00218."
article_number: '10153 '
article_processing_charge: Yes
article_type: original
author:
- first_name: Nick N
  full_name: Machnik, Nick N
  id: 3591A0AA-F248-11E8-B48F-1D18A9856A87
  last_name: Machnik
  orcid: 0000-0001-6617-9742
- first_name: Seyed Mahdi
  full_name: Mahmoudi, Seyed Mahdi
  id: b9f6d5ef-7774-11eb-a47f-df2c75c02ee7
  last_name: Mahmoudi
- first_name: Malgorzata
  full_name: Borczyk, Malgorzata
  last_name: Borczyk
- first_name: Ilse
  full_name: Krätschmer, Ilse
  id: 30d4014e-7753-11eb-b44b-db6d61112e73
  last_name: Krätschmer
  orcid: 0000-0002-5636-9259
- first_name: Markus J.
  full_name: Bauer, Markus J.
  last_name: Bauer
- first_name: Matthew Richard
  full_name: Robinson, Matthew Richard
  id: E5D42276-F5DA-11E9-8E24-6303E6697425
  last_name: Robinson
  orcid: 0000-0001-8982-8813
citation:
  ama: Machnik NN, Mahmoudi SM, Borczyk M, Krätschmer I, Bauer MJ, Robinson MR. Causal
    inference for multiple risk factors and diseases from genomics data. <i>Nature
    Communications</i>. 2026;17. doi:<a href="https://doi.org/10.1038/s41467-026-76877-7">10.1038/s41467-026-76877-7</a>
  apa: Machnik, N. N., Mahmoudi, S. M., Borczyk, M., Krätschmer, I., Bauer, M. J.,
    &#38; Robinson, M. R. (2026). Causal inference for multiple risk factors and diseases
    from genomics data. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-026-76877-7">https://doi.org/10.1038/s41467-026-76877-7</a>
  chicago: Machnik, Nick N, Seyed Mahdi Mahmoudi, Malgorzata Borczyk, Ilse Krätschmer,
    Markus J. Bauer, and Matthew Richard Robinson. “Causal Inference for Multiple
    Risk Factors and Diseases from Genomics Data.” <i>Nature Communications</i>. Springer
    Nature, 2026. <a href="https://doi.org/10.1038/s41467-026-76877-7">https://doi.org/10.1038/s41467-026-76877-7</a>.
  ieee: N. N. Machnik, S. M. Mahmoudi, M. Borczyk, I. Krätschmer, M. J. Bauer, and
    M. R. Robinson, “Causal inference for multiple risk factors and diseases from
    genomics data,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.
  ista: Machnik NN, Mahmoudi SM, Borczyk M, Krätschmer I, Bauer MJ, Robinson MR. 2026.
    Causal inference for multiple risk factors and diseases from genomics data. Nature
    Communications. 17, 10153.
  mla: Machnik, Nick N., et al. “Causal Inference for Multiple Risk Factors and Diseases
    from Genomics Data.” <i>Nature Communications</i>, vol. 17, 10153, Springer Nature,
    2026, doi:<a href="https://doi.org/10.1038/s41467-026-76877-7">10.1038/s41467-026-76877-7</a>.
  short: N.N. Machnik, S.M. Mahmoudi, M. Borczyk, I. Krätschmer, M.J. Bauer, M.R.
    Robinson, Nature Communications 17 (2026).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: "This project uses the UK Biobank data under project number
  35520.\r\nUK Biobank genotypic and phenotypic data is available through a\r\nformal
  request at (http://www.ukbiobank.ac.uk). All of the data generated\r\nin this study
  are provided in the Source Data file. Source data\r\nare provided with this paper.
  The CI-GWAS code is fully open source and available at https://github.\r\ncom/medical-genomics-group/ci-gwasand
  has been archived on\r\nZenodo52. The scripts used to execute the model are available
  at\r\nhttps://github.com/medical-genomics-group/ci-gwas. R version 4.2.1 is\r\navailable
  at https://www.r-project.org/. Plink version 1.9 is available at\r\nhttps://www.cog-genomics.org/plink/1.9/."
date_created: 2026-10-04T22:01:53Z
date_published: 2026-08-25T00:00:00Z
date_updated: 2026-10-16T11:01:16Z
day: '25'
ddc:
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department:
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doi: 10.1038/s41467-026-76877-7
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intvolume: '        17'
language:
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license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '08'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
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    relation: earlier_version
    status: public
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: no
title: Causal inference for multiple risk factors and diseases from genomics data
tmp:
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  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '23152'
abstract:
- lang: eng
  text: "We present a panchromatic optical-millimeter characterization of GNz7q, a
    recently identified X-ray-weak,\r\nrapidly growing red quasar embedded within
    a dusty starburst galaxy at z = 7.1899, using the full suite of JWST/\r\nNIRCam,
    NIRSpec, Mid-Infrared Instrument (MIRI), and archival NOEMA observations. Our
    deep NIRSpec/\r\nG395M spectroscopy reveals unambiguous broad Balmer emission
    (FWHM = 2221 ± 20 km s\r\n−1\r\n), confirming a\r\nsuper-Eddington accreting black
    hole (BH) (λEdd = 2.7 ± 0.4) with a mass of\r\nlog(MBH/M ) = 7.55 ± 0.34,\r\nusing
    accretion-rate-corrected BH mass estimators. After subtracting the point source,
    we robustly detect stellar\r\nemission from the host galaxy across multiple NIRCam
    and MIRI filters. Our joint morphological-spectral\r\nanalysis yields a stellar
    mass of = ± * log(M /M ) 10.5 0.4\r\nand an intense star formation rate of\r\nSFR
    = 330 ± 97 M⊙ yr−1\r\n, confirming the host as a massive, dusty starburst galaxy.
    We find that GNz7q lies\r\non the local MBH–M* relation (MBH/M* ≃ 0.001) and is
    well positioned to evolve into the locus of massive Sloan\r\nDigital Sky Survey
    (SDSS) quasars with\r\nlog(MBH/M ) 9\r\nand M* ≈ 1011 M⊙ at z ∼ 6, owing to its
    remarkably\r\nrapid growth in both the BH and its host galaxy. This stands in
    stark contrast to many recently reported JWST\r\nactive galactic nucleus populations
    at similar redshifts, including the little red dots, whose weak or undetected
    star\r\nformation makes it difficult for them to grow into the massive galaxies
    hosting SDSS-like quasars. These results\r\nsuggest that GNz7q marks a rare, pivotal
    phase of early BH–galaxy coevolution, plausibly providing a crucial\r\ndirect
    pathway to the supermassive BH systems within the first billion years of the Universe."
acknowledgement: "We are grateful to Jinyi Yang and Feige Wang for their insightful
  discussions about the broad-line fitting. We are grateful to Zhiwei Pan and Yuming
  Fu for their discussions about the BH mass estimator.\r\n\r\nK.I. acknowledges support
  from the National Natural Science Foundation of China (12573015, W2532003), the
  Beijing Natural Science Foundation (IS25003), and the China Manned Space Program
  (CMS-CSST-2025-A09). LCH was supported by the National Science Foundation of China
  (12233001) and the China Manned Space Program (CMS-CSST-2025-A09). P.G.P.-G. acknowledges
  support from grant PID2022-139567NB-I00 funded by the Spanish Ministerio de Ciencia,
  Innovación y Universidades MCIU/AEI/10.13039/501100011033, FEDER Una manera de hacer
  Europa. J.A.-M. acknowledges support by grants PID2024-158856NA-I00 & PIB2021-127718NB-I00
  from the Spanish Ministry of Science and Innovation/State Agency of Research MCIN/AEI/10.13039/501100011033
  and by “ERDF A way of making Europe.”\r\n\r\nThis work is based on observations
  made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from
  the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute,
  which is operated by the Association of Universities for Research in Astronomy,
  Inc., under NASA contract NAS 5-03127 for JWST. The specific observations analyzed
  can be accessed via DOI: 10.17909/q19z-a348for the GNz7q observations and DOI: 10.17909/0akt-xx69for
  the MIRI images from the MEOW survey. These observations are associated with programs
  # 4762 and # 5407."
article_number: '86'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Qinyue
  full_name: Fei, Qinyue
  last_name: Fei
- first_name: Seiji
  full_name: Fujimoto, Seiji
  last_name: Fujimoto
- first_name: Gabriel
  full_name: Brammer, Gabriel
  last_name: Brammer
- first_name: Ruancun
  full_name: Li, Ruancun
  last_name: Li
- first_name: Luis C.
  full_name: Ho, Luis C.
  last_name: Ho
- first_name: Volker
  full_name: Bromm, Volker
  last_name: Bromm
- first_name: Javier
  full_name: Álvarez-Márquez, Javier
  last_name: Álvarez-Márquez
- first_name: Yoshihisa
  full_name: Asada, Yoshihisa
  last_name: Asada
- first_name: Guillermo
  full_name: Barro, Guillermo
  last_name: Barro
- first_name: Luis
  full_name: Colina, Luis
  last_name: Colina
- first_name: Pratika
  full_name: Dayal, Pratika
  last_name: Dayal
- first_name: Steven L.
  full_name: Finkelstein, Steven L.
  last_name: Finkelstein
- first_name: Johan P.U.
  full_name: Fynbo, Johan P.U.
  last_name: Fynbo
- first_name: Michele
  full_name: Ginolfi, Michele
  last_name: Ginolfi
- first_name: Kohei
  full_name: Inayoshi, Kohei
  last_name: Inayoshi
- first_name: Vasily
  full_name: Kokorev, Vasily
  last_name: Kokorev
- first_name: Gene C.K.
  full_name: Leung, Gene C.K.
  last_name: Leung
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Romain A.
  full_name: Meyer, Romain A.
  last_name: Meyer
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Masafusa
  full_name: Onoue, Masafusa
  last_name: Onoue
- first_name: Pablo G.
  full_name: Pérez-González, Pablo G.
  last_name: Pérez-González
- first_name: Charles L.
  full_name: Steinhardt, Charles L.
  last_name: Steinhardt
- first_name: Francesco
  full_name: Valentino, Francesco
  last_name: Valentino
- first_name: Fabian
  full_name: Walter, Fabian
  last_name: Walter
- first_name: Mengyuan
  full_name: Xiao, Mengyuan
  last_name: Xiao
- first_name: Haowen
  full_name: Zhang, Haowen
  last_name: Zhang
citation:
  ama: 'Fei Q, Fujimoto S, Brammer G, et al. Direct pathway to the early supermassive
    Black Holes: A red super-Eddington quasar in a massive starburst host at z = 7.2.
    <i>The Astrophysical Journal</i>. 2026;1010(1). doi:<a href="https://doi.org/10.3847/1538-4357/aea07b">10.3847/1538-4357/aea07b</a>'
  apa: 'Fei, Q., Fujimoto, S., Brammer, G., Li, R., Ho, L. C., Bromm, V., … Zhang,
    H. (2026). Direct pathway to the early supermassive Black Holes: A red super-Eddington
    quasar in a massive starburst host at z = 7.2. <i>The Astrophysical Journal</i>.
    IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/aea07b">https://doi.org/10.3847/1538-4357/aea07b</a>'
  chicago: 'Fei, Qinyue, Seiji Fujimoto, Gabriel Brammer, Ruancun Li, Luis C. Ho,
    Volker Bromm, Javier Álvarez-Márquez, et al. “Direct Pathway to the Early Supermassive
    Black Holes: A Red Super-Eddington Quasar in a Massive Starburst Host at z = 7.2.”
    <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href="https://doi.org/10.3847/1538-4357/aea07b">https://doi.org/10.3847/1538-4357/aea07b</a>.'
  ieee: 'Q. Fei <i>et al.</i>, “Direct pathway to the early supermassive Black Holes:
    A red super-Eddington quasar in a massive starburst host at z = 7.2,” <i>The Astrophysical
    Journal</i>, vol. 1010, no. 1. IOP Publishing, 2026.'
  ista: 'Fei Q, Fujimoto S, Brammer G, Li R, Ho LC, Bromm V, Álvarez-Márquez J, Asada
    Y, Barro G, Colina L, Dayal P, Finkelstein SL, Fynbo JPU, Ginolfi M, Inayoshi
    K, Kokorev V, Leung GCK, Matthee JJ, Meyer RA, Naidu RP, Onoue M, Pérez-González
    PG, Steinhardt CL, Valentino F, Walter F, Xiao M, Zhang H. 2026. Direct pathway
    to the early supermassive Black Holes: A red super-Eddington quasar in a massive
    starburst host at z = 7.2. The Astrophysical Journal. 1010(1), 86.'
  mla: 'Fei, Qinyue, et al. “Direct Pathway to the Early Supermassive Black Holes:
    A Red Super-Eddington Quasar in a Massive Starburst Host at z = 7.2.” <i>The Astrophysical
    Journal</i>, vol. 1010, no. 1, 86, IOP Publishing, 2026, doi:<a href="https://doi.org/10.3847/1538-4357/aea07b">10.3847/1538-4357/aea07b</a>.'
  short: Q. Fei, S. Fujimoto, G. Brammer, R. Li, L.C. Ho, V. Bromm, J. Álvarez-Márquez,
    Y. Asada, G. Barro, L. Colina, P. Dayal, S.L. Finkelstein, J.P.U. Fynbo, M. Ginolfi,
    K. Inayoshi, V. Kokorev, G.C.K. Leung, J.J. Matthee, R.A. Meyer, R.P. Naidu, M.
    Onoue, P.G. Pérez-González, C.L. Steinhardt, F. Valentino, F. Walter, M. Xiao,
    H. Zhang, The Astrophysical Journal 1010 (2026).
das_tickbox: '1'
dataavailabilitystatement: "The reduced 1D NIRSpec/G395M spectra, the MIRI LRS 1D
  extraction, and the MIRI MRS 1D extraction used in this work are publicly available
  on Zenodo at DOI: 10.5281/zenodo.21539999.\r\nFacilities: JWST - James Webb Space
  Telescope, IRAM:NOEMA. -\r\nSoftware: GalfitS (R. Li et al. 2026), LMFIT (M. Newville
  et al. 2014), grizli (G. Brammer & J. Matharu 2021), msaexp (G. Brammer 2023)"
date_created: 2026-10-18T22:01:51Z
date_published: 2026-10-10T00:00:00Z
date_updated: 2026-10-19T06:48:25Z
day: '10'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.3847/1538-4357/aea07b
external_id:
  arxiv:
  - '2602.12325'
file:
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  checksum: b319631e496b3f50fd32202bb19a5b99
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  creator: dernst
  date_created: 2026-10-19T06:36:24Z
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  file_id: '23162'
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file_date_updated: 2026-10-19T06:36:24Z
fulldoi: https://doi.org/10.3847/1538-4357/aea07b
has_accepted_license: '1'
intvolume: '      1010'
issue: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: 'Direct pathway to the early supermassive Black Holes: A red super-Eddington
  quasar in a massive starburst host at z = 7.2'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1010
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '23148'
abstract:
- lang: eng
  text: Presenilin-1 (PS1) is an endoplasmic reticulum protein, most known for its
    role in pathogenesis of familial Alzheimer’s Disease (AD). PS1 has been attributed
    roles in intracellular calcium homeostasis in the brain, as well as in the pancreatic
    beta cells, where it has been shown to be fundamental for the initial phase of
    glucose-induced insulin secretion. To gain mechanistic insight into beta cell
    autonomous function of PS1, we have examined various beta cell models and found
    that PS1 controls glycolytic flux of pancreatic beta cells by regulating sub-mitochondrial
    Ca2+ homeostasis. Transient knock down of PS1 yielded a glycolytic bottleneck
    at the step catalyzed by glyceraldehyde-3-phosphate dehydrogenase, resulting in
    defective glucose responsiveness. Moreover, we show that PS1 is needed for the
    preservation of beta cell identity, likely due to its role in glycolysis. Finally,
    we show that mouse islets from an in vivo model of AD mimic the defective glucose
    responsiveness seen in beta cells with transient PS1 knock down, while the identity
    loss and whole-body glucose homeostasis are not severely impacted, suggesting
    an adaptive response. Thus, the current work highlights beta cell autonomous role
    of PS1 and adds a layer of complexity in its impact on whole body metabolism.
acknowledgement: We appreciate the technical assistance from Anna Schreilechner. We
  are grateful for support by all members of the animal facility team at IMB, University
  of Graz, as well as K. Zierler for assistance with animal licenses.  F.M, T.E.,
  T.M., T.P., and W.F.G. are grateful to the Austrian Science Fund (FWF) for the excellence
  cluster 10.55776/COE14 (MetAGE), which was additionally supported by Land Styria,
  Stadt Graz, University of Graz and Medical University of Graz. This research was
  further supported by the FWF via the DKplus program 10.55776/W1226 (DK-MCD) to F.M.,
  T.M., R.B.G., and W.F.G., 10.55776/P28529, 10.55776/I3716 (to R.M.), 10.55776/P28854,
  10.55776/I3792, 10.55776/DOC130 (to T.M.), and 10.55776/I4319 (to. M.S.R.); the
  Austrian Research Promotion Agency (FFG) grants 864690 and 870454; the Integrative
  Metabolism Research Center Graz; the Austrian Infrastructure Program 2016/2017 (to
  T.M.), and 10.55776/COE7, 10.55776/COE17, 10.55776/FG12 and 10.55776/F73 (to R.B.G.);
  the Styrian Government; the City of Graz; and BioTechMed-Graz (flagship project)
  (to T.M.); the MEFO Graz (to W.F.G.). F.E.O., J.G. and Z.K. were doctoral fellows
  in the doctoral program Metabolic and Cardiovascular Disease (MCD) (FWF, 10.55776/W
  1226) at the Medical University of Graz. S.v.A. and A.S. are thesis students in
  the excellence cluster 10.55776/COE14 (MetAGE, W.F.G.). M.H. was a fellow of the
  Molecular Medicine (MolMed) doctoral program at the Medical University of Graz supported
  by MEFO Graz. The SIM equipment is part of the Nikon Center of Excellence, Graz,
  and is supported by the Austrian infrastructure program 2013/ 2014, Nikon Austria
  Inc., and BioTechMed (to W.F.G.). Our thanks go to Shimadzu Austria for supporting
  this research through instrument access given in the Metabolomics and Bioprocess
  Analytics laboratory (TU Wien) (R.B.G.). For open access purposes, the authors have
  applied a CC BY public copyright license to any author-accepted manuscript version
  arising from this submission.” We thank the Medical University of Graz for financial
  support.
article_number: '1315'
article_processing_charge: Yes
article_type: original
author:
- first_name: Zhanat
  full_name: Koshenov, Zhanat
  last_name: Koshenov
- first_name: Sandra
  full_name: Postic, Sandra
  last_name: Postic
- first_name: Gabriela
  full_name: Schoiswohl, Gabriela
  last_name: Schoiswohl
- first_name: Savina
  full_name: Van Amsterdam, Savina
  last_name: Van Amsterdam
- first_name: Victoria
  full_name: Hois-Zelinka, Victoria
  last_name: Hois-Zelinka
- first_name: Furkan E.
  full_name: Oflaz, Furkan E.
  last_name: Oflaz
- first_name: Rene
  full_name: Rost, Rene
  last_name: Rost
- first_name: Oleksandra
  full_name: Tiapko, Oleksandra
  last_name: Tiapko
- first_name: Benjamin
  full_name: Gottschalk, Benjamin
  last_name: Gottschalk
- first_name: Martin
  full_name: Hirtl, Martin
  last_name: Hirtl
- first_name: Olaf G.
  full_name: Bachkoenig, Olaf G.
  last_name: Bachkoenig
- first_name: Aigerim
  full_name: Koshenova, Aigerim
  last_name: Koshenova
- first_name: Yusuf C.
  full_name: Erdogan, Yusuf C.
  last_name: Erdogan
- first_name: Adlet
  full_name: Sagintayev, Adlet
  last_name: Sagintayev
- first_name: Anita
  full_name: Krnjic, Anita
  last_name: Krnjic
- first_name: Johannes U.
  full_name: Pfabe, Johannes U.
  last_name: Pfabe
- first_name: Srdjan
  full_name: Sarikas, Srdjan
  id: 35F0286E-F248-11E8-B48F-1D18A9856A87
  last_name: Sarikas
- first_name: Bernhard
  full_name: Hochreiter, Bernhard
  id: e6cab3de-17f6-11ed-9210-c1e42e045e9d
  last_name: Hochreiter
- first_name: Juergen
  full_name: Gindlhuber, Juergen
  last_name: Gindlhuber
- first_name: Matthias
  full_name: Schittmayer, Matthias
  last_name: Schittmayer
- first_name: Jelena
  full_name: Tadic, Jelena
  last_name: Tadic
- first_name: Barbara
  full_name: Ehall, Barbara
  last_name: Ehall
- first_name: Frank
  full_name: Madeo, Frank
  last_name: Madeo
- first_name: Tobias
  full_name: Madl, Tobias
  last_name: Madl
- first_name: Roland
  full_name: Malli, Roland
  last_name: Malli
- first_name: Ruth
  full_name: Birner-Gruenberger, Ruth
  last_name: Birner-Gruenberger
- first_name: Thomas
  full_name: Pieber, Thomas
  last_name: Pieber
- first_name: Tobias
  full_name: Eisenberg, Tobias
  last_name: Eisenberg
- first_name: Marjan
  full_name: Slak Rupnik, Marjan
  last_name: Slak Rupnik
- first_name: Wolfgang F.
  full_name: Graier, Wolfgang F.
  last_name: Graier
citation:
  ama: Koshenov Z, Postic S, Schoiswohl G, et al. Presenilin-1 controls glycolysis
    and identity of pancreatic beta cells. <i>Communications Biology</i>. 2026;9.
    doi:<a href="https://doi.org/10.1038/s42003-026-10581-6">10.1038/s42003-026-10581-6</a>
  apa: Koshenov, Z., Postic, S., Schoiswohl, G., Van Amsterdam, S., Hois-Zelinka,
    V., Oflaz, F. E., … Graier, W. F. (2026). Presenilin-1 controls glycolysis and
    identity of pancreatic beta cells. <i>Communications Biology</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s42003-026-10581-6">https://doi.org/10.1038/s42003-026-10581-6</a>
  chicago: Koshenov, Zhanat, Sandra Postic, Gabriela Schoiswohl, Savina Van Amsterdam,
    Victoria Hois-Zelinka, Furkan E. Oflaz, Rene Rost, et al. “Presenilin-1 Controls
    Glycolysis and Identity of Pancreatic Beta Cells.” <i>Communications Biology</i>.
    Springer Nature, 2026. <a href="https://doi.org/10.1038/s42003-026-10581-6">https://doi.org/10.1038/s42003-026-10581-6</a>.
  ieee: Z. Koshenov <i>et al.</i>, “Presenilin-1 controls glycolysis and identity
    of pancreatic beta cells,” <i>Communications Biology</i>, vol. 9. Springer Nature,
    2026.
  ista: Koshenov Z, Postic S, Schoiswohl G, Van Amsterdam S, Hois-Zelinka V, Oflaz
    FE, Rost R, Tiapko O, Gottschalk B, Hirtl M, Bachkoenig OG, Koshenova A, Erdogan
    YC, Sagintayev A, Krnjic A, Pfabe JU, Sarikas S, Hochreiter B, Gindlhuber J, Schittmayer
    M, Tadic J, Ehall B, Madeo F, Madl T, Malli R, Birner-Gruenberger R, Pieber T,
    Eisenberg T, Slak Rupnik M, Graier WF. 2026. Presenilin-1 controls glycolysis
    and identity of pancreatic beta cells. Communications Biology. 9, 1315.
  mla: Koshenov, Zhanat, et al. “Presenilin-1 Controls Glycolysis and Identity of
    Pancreatic Beta Cells.” <i>Communications Biology</i>, vol. 9, 1315, Springer
    Nature, 2026, doi:<a href="https://doi.org/10.1038/s42003-026-10581-6">10.1038/s42003-026-10581-6</a>.
  short: Z. Koshenov, S. Postic, G. Schoiswohl, S. Van Amsterdam, V. Hois-Zelinka,
    F.E. Oflaz, R. Rost, O. Tiapko, B. Gottschalk, M. Hirtl, O.G. Bachkoenig, A. Koshenova,
    Y.C. Erdogan, A. Sagintayev, A. Krnjic, J.U. Pfabe, S. Sarikas, B. Hochreiter,
    J. Gindlhuber, M. Schittmayer, J. Tadic, B. Ehall, F. Madeo, T. Madl, R. Malli,
    R. Birner-Gruenberger, T. Pieber, T. Eisenberg, M. Slak Rupnik, W.F. Graier, Communications
    Biology 9 (2026).
das_tickbox: '1'
dataavailabilitystatement: The data supporting the findings of this research can be
  obtained from the authors upon a reasonable request; please refer to the author’s
  contributions for details regarding specific datasets. Numerical source data underlying
  graphs in this article can be found in Supplementary data file. Supplementary Figs.
  and figure legends are included in the Supplementary file. The code used in this
  study is available from the authors on reasonable request.
date_created: 2026-10-18T22:01:50Z
date_published: 2026-10-08T00:00:00Z
date_updated: 2026-10-19T06:23:26Z
day: '08'
ddc:
- '570'
department:
- _id: FISS
doi: 10.1038/s42003-026-10581-6
external_id:
  pmid:
  - '42387039'
file:
- access_level: open_access
  checksum: b90e60a625fcac8ef5d9ff968792d675
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-19T06:19:39Z
  date_updated: 2026-10-19T06:19:39Z
  file_id: '23161'
  file_name: 2026_CommunicationsBiology_Koshenov.pdf
  file_size: 1819866
  relation: main_file
  success: 1
file_date_updated: 2026-10-19T06:19:39Z
fulldoi: https://doi.org/10.1038/s42003-026-10581-6
has_accepted_license: '1'
intvolume: '         9'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Communications Biology
publication_identifier:
  eissn:
  - 2399-3642
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Presenilin-1 controls glycolysis and identity of pancreatic beta cells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '23150'
abstract:
- lang: eng
  text: "High-redshift supermassive black holes (SMBHs) have challenged our understanding
    of black hole formation and growth. The ‘heavy-seed’ pathway eases the problem
    with the progenitors of these SMBHs having birth masses up to∼105 M\x03. Here,
    we investigate the possibility that a local dwarf galaxy, Leo I, harbours a heavy-seed
    descendant. Using Monte Carlo merger trees to generate the merger histories of
    1000 dark matter haloes similar to the Milky Way (MW), we search for Leo- like
    satellite haloes and investigate the probability that the progenitors of these
    satellites formed a heavy seed. We derive the likelihood of such ‘heavy-seed survivors’
    (HSSs) across various formation and survival criteria as well as Leo-similarity
    criteria. We find that the virial temperature for the onset of atomic cooling
    and rapid gas infall that yields heavy seeds, Tact , has the largest impact on
    HSS frequency. We find HSSs in a fraction 0.7 per cent, 18.1 per cent, and 96.5
    per cent of MW-like haloes when Tact is set to 9000, 7000, and 5000 K, respectively.
    For the canonical atomic-cooling threshold ( Tact \x02 8000 K), the HSS fraction
    is\x03 1per cent , indicating that Leo I hosting a heavy-seed descendant is unlikely
    under well-motivated physical assumptions. Higher HSS fractions occur only under
    optimistic and currently unsubstantiated assumptions on Tact . Nevertheless, these
    results motivate future work that clarifies the possibility of heavy-seed BH formation
    in pristine haloes with nominal virial temperatures below 8000 K. This may motivate
    Leo I as a target for disentangling heavy seeds from other SMBH formation mechanisms."
acknowledgement: We thank the anonymous reviewer for feedback that helped clarify
  this manuscript. ZH acknowledges support from NSF grant AST-2006176. FP acknowledges
  support from the Black Hole Initiative at Harvard University, which is funded by
  grants from the John Templeton Foundation and the Gordon and Betty Moore Foundation.
  Merger tree generation and analysis were performed with NSF’s ACCESS allocations
  AST-120046 and AST-140041 on the Stampede3 resource. The freely available plotting
  library matplotlib (J. D. Hunter 2007) was used to construct the plots in this paper.
article_number: stag1839
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Matthew T.
  full_name: Scoggins, Matthew T.
  last_name: Scoggins
- first_name: Zoltán
  full_name: Haiman, Zoltán
  id: 7c006e8c-cc0d-11ee-8322-cb904ef76f36
  last_name: Haiman
  orcid: 0000-0003-3633-5403
- first_name: Fabio
  full_name: Pacucci, Fabio
  last_name: Pacucci
citation:
  ama: 'Scoggins MT, Haiman Z, Pacucci F. Heavy black hole seed survivors in dwarf
    galaxies: A case study of Leo I. <i>Monthly Notices of the Royal Astronomical
    Society</i>. 2026;552(3). doi:<a href="https://doi.org/10.1093/mnras/stag1839">10.1093/mnras/stag1839</a>'
  apa: 'Scoggins, M. T., Haiman, Z., &#38; Pacucci, F. (2026). Heavy black hole seed
    survivors in dwarf galaxies: A case study of Leo I. <i>Monthly Notices of the
    Royal Astronomical Society</i>. Oxford University Press. <a href="https://doi.org/10.1093/mnras/stag1839">https://doi.org/10.1093/mnras/stag1839</a>'
  chicago: 'Scoggins, Matthew T., Zoltán Haiman, and Fabio Pacucci. “Heavy Black Hole
    Seed Survivors in Dwarf Galaxies: A Case Study of Leo I.” <i>Monthly Notices of
    the Royal Astronomical Society</i>. Oxford University Press, 2026. <a href="https://doi.org/10.1093/mnras/stag1839">https://doi.org/10.1093/mnras/stag1839</a>.'
  ieee: 'M. T. Scoggins, Z. Haiman, and F. Pacucci, “Heavy black hole seed survivors
    in dwarf galaxies: A case study of Leo I,” <i>Monthly Notices of the Royal Astronomical
    Society</i>, vol. 552, no. 3. Oxford University Press, 2026.'
  ista: 'Scoggins MT, Haiman Z, Pacucci F. 2026. Heavy black hole seed survivors in
    dwarf galaxies: A case study of Leo I. Monthly Notices of the Royal Astronomical
    Society. 552(3), stag1839.'
  mla: 'Scoggins, Matthew T., et al. “Heavy Black Hole Seed Survivors in Dwarf Galaxies:
    A Case Study of Leo I.” <i>Monthly Notices of the Royal Astronomical Society</i>,
    vol. 552, no. 3, stag1839, Oxford University Press, 2026, doi:<a href="https://doi.org/10.1093/mnras/stag1839">10.1093/mnras/stag1839</a>.'
  short: M.T. Scoggins, Z. Haiman, F. Pacucci, Monthly Notices of the Royal Astronomical
    Society 552 (2026).
das_tickbox: '1'
dataavailabilitystatement: The code used to analyse the merger trees and generate
  figures for this manuscript is available at this GitHub repository. All other data
  will be shared upon reasonable request to the corresponding author.
date_created: 2026-10-18T22:01:51Z
date_published: 2026-11-01T00:00:00Z
date_updated: 2026-10-19T07:05:55Z
day: '01'
ddc:
- '520'
department:
- _id: ZoHa
doi: 10.1093/mnras/stag1839
external_id:
  arxiv:
  - '2511.04736'
file:
- access_level: open_access
  checksum: 99a35f1305b7f1ed3813bcd51ba16724
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-19T07:05:43Z
  date_updated: 2026-10-19T07:05:43Z
  file_id: '23164'
  file_name: 2026_MonthNoticesRAS_Scoggins.pdf
  file_size: 1450204
  relation: main_file
  success: 1
file_date_updated: 2026-10-19T07:05:43Z
fulldoi: https://doi.org/10.1093/mnras/stag1839
has_accepted_license: '1'
intvolume: '       552'
issue: '3'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'Heavy black hole seed survivors in dwarf galaxies: A case study of Leo I'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 552
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '23151'
abstract:
- lang: eng
  text: "We present deep, narrowband Gemini North/GMOS images of the Pa 30 nebula
    that reveal rich small-scale\r\nstructure in the ejecta filaments. In [S II],
    the number of detected filaments increases by about an order of\r\nmagnitude compared
    to previous studies. The imaging further reveals that the filaments are not smooth
    radial\r\nstreaks, but instead are composed of cascades of knots or clumps. The
    images in [O III] yield the first confirmation\r\nthat previously detected diffuse
    [O III] emission in fact originates from the same [S II] filaments. We measure
    a\r\nnebula center consistent with the position of the central star, indicating
    that the remnant has not received a large\r\ntransverse kick. The 3σ upper limit
    on the velocity of the stellar kick is ≲100 km s\r\n−1\r\n. Cross-sectional profiles
    of\r\nthe filaments in [S II] and [O III] show a central peak on top of a nebula
    background, the latter being likely due to\r\ndiffuse emission or unresolved filaments.
    The median [S II] width of 0.7 is slightly broader than the 0.50 seeing,\r\nproviding
    some evidence of partially resolved filaments and implying a characteristic knot
    diameter of ∼1016 cm.\r\nThe ≈1″ widths measured in [O III] are consistent with
    the poorer seeing of the oxygen images. The discovery of\r\nthis clumpy substructure
    provides a new observational constraint on models for the origin and evolution
    of the\r\nremarkable filamentary ejecta of Pa 30."
acknowledgement: "We thank Jim Fuller, SR Kulkarni, David Charbonneau, Paul Duffell,
  Abigail Polin, Miranda Pikus, Tony Piro, Lars Bildsten, Eliot Quartert, and Rob
  Fesen for helpful discussions. This work was supported by NASA through the NASA
  Hubble Fellowship grant HST-HF2-51527.001-A awarded by the Space Telescope Science
  Institute, which is operated by the Association of Universities for Research in
  Astronomy, Inc., for NASA, under contract NAS5-26555.\r\n\r\nFacility: Gemini:Gillett
  (GMOS-N) - .\r\n\r\nSoftware: astropy (Astropy Collaboration et al. 2013, 2018),
  scipy (P. Virtanen et al. 2020), emcee (D. Foreman-Mackey et al. 2013), DRAGONS
  (K. Labrie et al. 2023), DS9 (W. A. Joye & E. Mandel 2003)."
article_number: '28'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Tim
  full_name: Cunningham, Tim
  last_name: Cunningham
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: John C.
  full_name: Raymond, John C.
  last_name: Raymond
- first_name: Scott J.
  full_name: Kenyon, Scott J.
  last_name: Kenyon
citation:
  ama: Cunningham T, Caiazzo I, Raymond JC, Kenyon SJ. Detection of knots in the type
    Iax supernova remnant Pa 30. <i>The Astrophysical Journal</i>. 2026;1010(1). doi:<a
    href="https://doi.org/10.3847/1538-4357/ae9cb2">10.3847/1538-4357/ae9cb2</a>
  apa: Cunningham, T., Caiazzo, I., Raymond, J. C., &#38; Kenyon, S. J. (2026). Detection
    of knots in the type Iax supernova remnant Pa 30. <i>The Astrophysical Journal</i>.
    IOP Publishing. <a href="https://doi.org/10.3847/1538-4357/ae9cb2">https://doi.org/10.3847/1538-4357/ae9cb2</a>
  chicago: Cunningham, Tim, Ilaria Caiazzo, John C. Raymond, and Scott J. Kenyon.
    “Detection of Knots in the Type Iax Supernova Remnant Pa 30.” <i>The Astrophysical
    Journal</i>. IOP Publishing, 2026. <a href="https://doi.org/10.3847/1538-4357/ae9cb2">https://doi.org/10.3847/1538-4357/ae9cb2</a>.
  ieee: T. Cunningham, I. Caiazzo, J. C. Raymond, and S. J. Kenyon, “Detection of
    knots in the type Iax supernova remnant Pa 30,” <i>The Astrophysical Journal</i>,
    vol. 1010, no. 1. IOP Publishing, 2026.
  ista: Cunningham T, Caiazzo I, Raymond JC, Kenyon SJ. 2026. Detection of knots in
    the type Iax supernova remnant Pa 30. The Astrophysical Journal. 1010(1), 28.
  mla: Cunningham, Tim, et al. “Detection of Knots in the Type Iax Supernova Remnant
    Pa 30.” <i>The Astrophysical Journal</i>, vol. 1010, no. 1, 28, IOP Publishing,
    2026, doi:<a href="https://doi.org/10.3847/1538-4357/ae9cb2">10.3847/1538-4357/ae9cb2</a>.
  short: T. Cunningham, I. Caiazzo, J.C. Raymond, S.J. Kenyon, The Astrophysical Journal
    1010 (2026).
corr_author: '1'
das_tickbox: '0'
date_created: 2026-10-18T22:01:51Z
date_published: 2026-10-10T00:00:00Z
date_updated: 2026-10-19T06:59:28Z
day: '10'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.3847/1538-4357/ae9cb2
external_id:
  arxiv:
  - '2610.06424'
file:
- access_level: open_access
  checksum: a31da77f9197b832da52caf1417a87de
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-19T06:57:17Z
  date_updated: 2026-10-19T06:57:17Z
  file_id: '23163'
  file_name: 2026_AstrophysicalJour_Cunningham.pdf
  file_size: 34494943
  relation: main_file
  success: 1
file_date_updated: 2026-10-19T06:57:17Z
fulldoi: https://doi.org/10.3847/1538-4357/ae9cb2
has_accepted_license: '1'
intvolume: '      1010'
issue: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: The Astrophysical Journal
publication_identifier:
  eissn:
  - 1538-4357
  issn:
  - 0004-637X
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Detection of knots in the type Iax supernova remnant Pa 30
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1010
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '23149'
abstract:
- lang: eng
  text: We prove an asymptotic formula for the number of integral points of bounded
    log anticanonical height on a singular quartic del Pezzo surface over arbitrary
    number fields, with respect to the largest admissible boundary divisor. The resulting
    Clemens complex is more complicated than usual, and leads to particularly interesting
    effective cone constants, associated with exponentially many polytopes whose volumes
    appear in the expected formula. Like a jigsaw puzzle, these polytopes fit together
    to one large polytope. The volume of this polytope appears in the asymptotic formula
    that we obtain using the universal torsor method via o-minimal structures.
acknowledgement: Open Access funding enabled and organized by Projekt DEAL. We would
  like to thank the referee for their careful reading and helpful remarks that helped
  to improve this article. The first two authors were supported by the Deutsche Forschungsgemeinschaft
  (DFG) – 512730679 (RTG2965). The third author was partially supported by the Caroline
  Herschel Programme of Leibniz University Hannover. The fourth author was supported
  by the Deutsche Forschungsgemeinschaft (DFG) – 398436923 (RTG2491).
article_number: '37'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Christian
  full_name: Bernert, Christian
  id: aefba9fc-4694-11f0-b73e-8bd408e8f734
  last_name: Bernert
- first_name: Ulrich
  full_name: Derenthal, Ulrich
  last_name: Derenthal
- first_name: Judith
  full_name: Ortmann, Judith
  last_name: Ortmann
- first_name: Florian Alexander
  full_name: Wilsch, Florian Alexander
  id: 560601DA-8D36-11E9-A136-7AC1E5697425
  last_name: Wilsch
  orcid: 0000-0001-7302-8256
citation:
  ama: 'Bernert C, Derenthal U, Ortmann J, Wilsch FA. Integral points over number
    fields: a Clemens complex jigsaw puzzle. <i>Mathematische Zeitschrift</i>. 2026;314(3).
    doi:<a href="https://doi.org/10.1007/s00209-026-04140-2">10.1007/s00209-026-04140-2</a>'
  apa: 'Bernert, C., Derenthal, U., Ortmann, J., &#38; Wilsch, F. A. (2026). Integral
    points over number fields: a Clemens complex jigsaw puzzle. <i>Mathematische Zeitschrift</i>.
    Springer. <a href="https://doi.org/10.1007/s00209-026-04140-2">https://doi.org/10.1007/s00209-026-04140-2</a>'
  chicago: 'Bernert, Christian, Ulrich Derenthal, Judith Ortmann, and Florian Alexander
    Wilsch. “Integral Points over Number Fields: A Clemens Complex Jigsaw Puzzle.”
    <i>Mathematische Zeitschrift</i>. Springer, 2026. <a href="https://doi.org/10.1007/s00209-026-04140-2">https://doi.org/10.1007/s00209-026-04140-2</a>.'
  ieee: 'C. Bernert, U. Derenthal, J. Ortmann, and F. A. Wilsch, “Integral points
    over number fields: a Clemens complex jigsaw puzzle,” <i>Mathematische Zeitschrift</i>,
    vol. 314, no. 3. Springer, 2026.'
  ista: 'Bernert C, Derenthal U, Ortmann J, Wilsch FA. 2026. Integral points over
    number fields: a Clemens complex jigsaw puzzle. Mathematische Zeitschrift. 314(3),
    37.'
  mla: 'Bernert, Christian, et al. “Integral Points over Number Fields: A Clemens
    Complex Jigsaw Puzzle.” <i>Mathematische Zeitschrift</i>, vol. 314, no. 3, 37,
    Springer, 2026, doi:<a href="https://doi.org/10.1007/s00209-026-04140-2">10.1007/s00209-026-04140-2</a>.'
  short: C. Bernert, U. Derenthal, J. Ortmann, F.A. Wilsch, Mathematische Zeitschrift
    314 (2026).
das_tickbox: '1'
dataavailabilitystatement: Our manuscript has no associated data.
date_created: 2026-10-18T22:01:50Z
date_published: 2026-11-01T00:00:00Z
date_updated: 2026-10-19T06:13:10Z
day: '01'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1007/s00209-026-04140-2
external_id:
  arxiv:
  - '2601.08774'
file:
- access_level: open_access
  checksum: c2157633b4832a760336cd5d3f77b022
  content_type: application/pdf
  creator: dernst
  date_created: 2026-10-19T06:11:23Z
  date_updated: 2026-10-19T06:11:23Z
  file_id: '23160'
  file_name: 2026_MathemZeitschrift_Bernert.pdf
  file_size: 593086
  relation: main_file
  success: 1
file_date_updated: 2026-10-19T06:11:23Z
fulldoi: https://doi.org/10.1007/s00209-026-04140-2
has_accepted_license: '1'
intvolume: '       314'
issue: '3'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Mathematische Zeitschrift
publication_identifier:
  eissn:
  - 1432-1823
  issn:
  - 0025-5874
publication_status: published
publisher: Springer
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'Integral points over number fields: a Clemens complex jigsaw puzzle'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 314
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '23156'
abstract:
- lang: eng
  text: "Extracting the current-phase relationship (CPR) of a single superconducting
    junction is challenging in practice and traditionally involves embedding the junction
    in a larger superconducting circuit containing SQUIDs and/or resonators. Applying
    ac driving to the junction has proven to be a viable and less invasive way to
    extract information about the few lowest harmonics of the CPR, by locating the
    integer and fractional Shapiro steps in the \U0001D43C⁢\U0001D449-curve of the
    driven junction. Here, we present an alternative driving-based method that allows
    to extract the full harmonic content of a CPR in a relatively noninvasive way,
    by fitting the measured critical currents of the driven junction as a function
    of driving power. We test our method, both using numerical simulations and in
    experiments, and we show that it works accurately."
acknowledgement: 'The authors thank Afonso Oliveira, Stefano Calcaterra, Daniel Chrastina,
  and Giovanni Isella for providing the Ge/SiGe heterostructure. This work was supported
  by the Research Council of Norway through its Centers of Excellence funding scheme,
  Project No. 262633, “QuSpin,” the FWF Project with DOI:10.55776/PAT7682124, OeAD
  “ISTA Austria: ISTernship Summer Programme, Non-EU countries” (Ref. No.: MPC-2025-00945),
  the Spanish Comunidad de Madrid (CM) “Talento Program” (Project No. 2022-T1/IND-24070),
  and the Spanish Ministry of Science, Innovation, and Universities through Grants
  No. CEX2024-001445-S (Severo Ochoa Centres of Excellence program) and No. PID2022-140552NA-I00,
  funded by MCIN/AEI/10.13039/501100011033.'
article_number: '044017'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Maxim
  full_name: Tjøtta, Maxim
  last_name: Tjøtta
- first_name: Devashish C
  full_name: Shah, Devashish C
  id: de191434-4e7e-11ef-bf4b-9a056fc19fc3
  last_name: Shah
  orcid: 0009-0007-5829-7707
- first_name: Kanishk
  full_name: Modi, Kanishk
  id: f05345fd-900f-11f1-bfd8-8c0b6eadcc7f
  last_name: Modi
- first_name: Marco
  full_name: Valentini, Marco
  id: C0BB2FAC-D767-11E9-B658-BC13E6697425
  last_name: Valentini
- first_name: Rubén
  full_name: Seoane Souto, Rubén
  last_name: Seoane Souto
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
- first_name: Jeroen
  full_name: Danon, Jeroen
  last_name: Danon
citation:
  ama: Tjøtta M, Shah DC, Modi K, et al. Fast-driving spectroscopy of current-phase
    relationships of individual Josephson elements. <i>Physical Review Applied</i>.
    2026;26(4). doi:<a href="https://doi.org/10.1103/d3gl-qntm">10.1103/d3gl-qntm</a>
  apa: Tjøtta, M., Shah, D. C., Modi, K., Valentini, M., Seoane Souto, R., Katsaros,
    G., &#38; Danon, J. (2026). Fast-driving spectroscopy of current-phase relationships
    of individual Josephson elements. <i>Physical Review Applied</i>. American Physical
    Society. <a href="https://doi.org/10.1103/d3gl-qntm">https://doi.org/10.1103/d3gl-qntm</a>
  chicago: Tjøtta, Maxim, Devashish C Shah, Kanishk Modi, Marco Valentini, Rubén Seoane
    Souto, Georgios Katsaros, and Jeroen Danon. “Fast-Driving Spectroscopy of Current-Phase
    Relationships of Individual Josephson Elements.” <i>Physical Review Applied</i>.
    American Physical Society, 2026. <a href="https://doi.org/10.1103/d3gl-qntm">https://doi.org/10.1103/d3gl-qntm</a>.
  ieee: M. Tjøtta <i>et al.</i>, “Fast-driving spectroscopy of current-phase relationships
    of individual Josephson elements,” <i>Physical Review Applied</i>, vol. 26, no.
    4. American Physical Society, 2026.
  ista: Tjøtta M, Shah DC, Modi K, Valentini M, Seoane Souto R, Katsaros G, Danon
    J. 2026. Fast-driving spectroscopy of current-phase relationships of individual
    Josephson elements. Physical Review Applied. 26(4), 044017.
  mla: Tjøtta, Maxim, et al. “Fast-Driving Spectroscopy of Current-Phase Relationships
    of Individual Josephson Elements.” <i>Physical Review Applied</i>, vol. 26, no.
    4, 044017, American Physical Society, 2026, doi:<a href="https://doi.org/10.1103/d3gl-qntm">10.1103/d3gl-qntm</a>.
  short: M. Tjøtta, D.C. Shah, K. Modi, M. Valentini, R. Seoane Souto, G. Katsaros,
    J. Danon, Physical Review Applied 26 (2026).
das_tickbox: '1'
dataavailabilitystatement: The data that support the findings of this article are
  openly available at [10.5281/zenodo.22646275].
date_created: 2026-10-18T22:01:52Z
date_published: 2026-10-01T00:00:00Z
date_updated: 2026-10-19T07:25:01Z
day: '01'
department:
- _id: GeKa
- _id: GradSch
doi: 10.1103/d3gl-qntm
external_id:
  arxiv:
  - '2511.14313'
fulldoi: https://doi.org/10.1103/d3gl-qntm
intvolume: '        26'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2511.14313
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 5b9e579c-ab3d-11f0-914f-88754c5b5a3f
  grant_number: PAT 7682124
  name: Superconducting spin qubits in planar Ge
publication: Physical Review Applied
publication_identifier:
  eissn:
  - 2331-7019
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Fast-driving spectroscopy of current-phase relationships of individual Josephson
  elements
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2026'
...
