@article{17776, abstract = {The gravitational waves (GW) emitted during the coalescence of supermassive black holes (SMBHs) in the mass range 10^4-10^7 M_sun will be detectable out to high redshifts with LISA. We calculate the size and orientation of the three-dimensional error ellipse in solid angle and redshift within which the LISA event could be localized using the GW signatures alone. We take into account uncertainties in LISA's measurements of the luminosity distance and direction to the source, in the background cosmology, in weak gravitational lensing magnification due to inhomogeneities along the line of sight, and potential source peculiar velocities. We find that weak lensing errors exceed other sources of uncertainties by nearly an order of magnitude. Under the plausible assumption that BH mergers are accompanied by gas accretion leading to Eddington-limited quasar activity, we then compute the number of quasars that would be found in a typical LISA error volume, as a function of BH mass and redshift. We find that low redshifts offer the best opportunities to identify quasar counterparts to cosmological standard sirens, and that the LISA error volume will typically contain a single near-Eddington quasar at z=1. This will allow a straightforward test of the hypothesis that BH mergers are accompanied by bright quasar activity and, if the hypothesis proves correct, will guarantee the identification of a unique quasar counterpart. This would yield unprecedented tests of the physics of SMBH accretion, and offer an alternative method to precisely constrain cosmological parameters.}, author = {Kocsis, Bence and Frei, Zsolt and Haiman, Zoltán and Menou, Kristen}, issn = {0004-637X}, journal = {The Astrophysical Journal}, number = {1}, pages = {27--37}, publisher = {American Astronomical Society}, title = {{Finding the electromagnetic counterparts of cosmological standard sirens}}, doi = {10.1086/498236}, volume = {637}, year = {2006}, } @article{17794, abstract = {We model the number of detectable supernovae (SNe) as a function of redshift at different flux thresholds, making use of the observed properties of local SNe, such as their light curves, fiducial spectra, and peak magnitude distributions. We assume that the star formation rate (SFR) at high redshift traces the formation rate of dark matter halos. We obtain a rate of 0.4-2.3 SNe arcmin^-2 yr^-1 at z ≳ 5 at the near-infrared (4.5 μm) flux density threshold of 3 nJy (achievable with the James Webb Space Telescope [JWST] in a 10^5 s integration). In a hypothetical 1 yr survey, it should be possible to detect up to several thousand SNe per unit redshift at z ~ 6. We discuss the possible application of such a large sample of distant SNe as a probe of the epoch of reionization. By heating the intergalactic medium (IGM) and raising the cosmological Jeans mass, the process of reionization can suppress star formation in low-mass galaxies. This could have produced a relatively sharp drop in the SN rate around the redshift of reionization (zre). We quantify the detectability of this feature in future surveys of distant SNe by varying the redshift and duration of reionization, as well as its impact on the SFR in low-mass halos, which results in different redshifts, widths, and sizes of the drop in the expected SFR. We find that the drop can be detected out to zre ~ 13, as long as (1) the reionization history contains a relatively rapid feature that is synchronized over different regions to within Δz ≲ 1-3, (2) the star formation efficiency in halos that dominate reionization is epsilon* ~ 10%, and (3) reionization significantly suppresses the star formation in low-mass halos. Depending on the details of (1)-(3), this could be achieved with a survey lasting less than 2 weeks. Detecting this signature would also help elucidate the feedback mechanism that regulates reionization.}, author = {Mesinger, Andrei and Johnson, Benjamin D. and Haiman, Zoltán}, issn = {0004-637X}, journal = {The Astrophysical Journal}, number = {1}, pages = {80--90}, publisher = {American Astronomical Society}, title = {{The redshift distribution of distant supernovae and its use in probing reionization}}, doi = {10.1086/498294}, volume = {637}, year = {2006}, } @article{8488, abstract = {We demonstrate for different protein samples that three-dimensional HNCO and HNCA correlation spectra may be recorded in a few minutes acquisition time using the band-selective excitation short-transient sequences presented here. This opens new perspectives for the NMR structural investigation of unstable protein samples and real-time site-resolved studies of protein kinetics.}, author = {Schanda, Paul and Van Melckebeke, Hélène and Brutscher, Bernhard}, issn = {0002-7863}, journal = {Journal of the American Chemical Society}, keywords = {Colloid and Surface Chemistry, Biochemistry, General Chemistry, Catalysis}, number = {28}, pages = {9042--9043}, publisher = {American Chemical Society}, title = {{Speeding up three-dimensional protein NMR experiments to a few minutes}}, doi = {10.1021/ja062025p}, volume = {128}, year = {2006}, } @article{8489, abstract = {Structure elucidation of proteins by either NMR or X‐ray crystallography often requires the screening of a large number of samples for promising protein constructs and optimum solution conditions. For large‐scale screening of protein samples in solution, robust methods are needed that allow a rapid assessment of the folding of a polypeptide under diverse sample conditions. Here we present HET‐SOFAST NMR, a highly sensitive new method for semi‐quantitative characterization of the structural compactness and heterogeneity of polypeptide chains in solution. On the basis of one‐dimensional 1H HET‐SOFAST NMR data, obtained on well‐folded, molten globular, partially‐ and completely unfolded proteins, we define empirical thresholds that can be used as quantitative benchmarks for protein compactness. For 15N‐enriched protein samples, two‐dimensional 1H‐15N HET‐SOFAST correlation spectra provide site‐specific information about the structural heterogeneity along the polypeptide chain.}, author = {Schanda, Paul and Forge, Vincent and Brutscher, Bernhard}, issn = {0749-1581}, journal = {Magnetic Resonance in Chemistry}, number = {S1}, pages = {S177--S184}, publisher = {Wiley}, title = {{HET-SOFAST NMR for fast detection of structural compactness and heterogeneity along polypeptide chains}}, doi = {10.1002/mrc.1825}, volume = {44}, year = {2006}, } @article{8490, abstract = {We demonstrate the feasibility of recording 1H–15N correlation spectra of proteins in only one second of acquisition time. The experiment combines recently proposed SOFAST-HMQC with Hadamard-type 15N frequency encoding. This allows site-resolved real-time NMR studies of kinetic processes in proteins with an increased time resolution. The sensitivity of the experiment is sufficient to be applicable to a wide range of molecular systems available at millimolar concentration on a high magnetic field spectrometer.}, author = {Schanda, Paul and Brutscher, Bernhard}, issn = {1090-7807}, journal = {Journal of Magnetic Resonance}, keywords = {Nuclear and High Energy Physics, Biophysics, Biochemistry, Condensed Matter Physics}, number = {2}, pages = {334--339}, publisher = {Elsevier}, title = {{Hadamard frequency-encoded SOFAST-HMQC for ultrafast two-dimensional protein NMR}}, doi = {10.1016/j.jmr.2005.10.007}, volume = {178}, year = {2006}, } @article{8513, author = {Kaloshin, Vadim and Saprykina, Maria}, issn = {1553-5231}, journal = {Discrete & Continuous Dynamical Systems - A}, number = {2}, pages = {611--640}, publisher = {American Institute of Mathematical Sciences (AIMS)}, title = {{Generic 3-dimensional volume-preserving diffeomorphisms with superexponential growth of number of periodic orbits}}, doi = {10.3934/dcds.2006.15.611}, volume = {15}, year = {2006}, } @article{8514, abstract = {We study the extent to which the Hausdorff dimension of a compact subset of an infinite-dimensional Banach space is affected by a typical mapping into a finite-dimensional space. It is possible that the dimension drops under all such mappings, but the amount by which it typically drops is controlled by the ‘thickness exponent’ of the set, which was defined by Hunt and Kaloshin (Nonlinearity12 (1999), 1263–1275). More precisely, let $X$ be a compact subset of a Banach space $B$ with thickness exponent $\tau$ and Hausdorff dimension $d$. Let $M$ be any subspace of the (locally) Lipschitz functions from $B$ to $\mathbb{R}^{m}$ that contains the space of bounded linear functions. We prove that for almost every (in the sense of prevalence) function $f \in M$, the Hausdorff dimension of $f(X)$ is at least $\min\{ m, d / (1 + \tau) \}$. We also prove an analogous result for a certain part of the dimension spectra of Borel probability measures supported on $X$. The factor $1 / (1 + \tau)$ can be improved to $1 / (1 + \tau / 2)$ if $B$ is a Hilbert space. Since dimension cannot increase under a (locally) Lipschitz function, these theorems become dimension preservation results when $\tau = 0$. We conjecture that many of the attractors associated with the evolution equations of mathematical physics have thickness exponent zero. We also discuss the sharpness of our results in the case $\tau > 0$.}, author = {OTT, WILLIAM and HUNT, BRIAN and Kaloshin, Vadim}, issn = {0143-3857}, journal = {Ergodic Theory and Dynamical Systems}, number = {3}, pages = {869--891}, publisher = {Cambridge University Press}, title = {{The effect of projections on fractal sets and measures in Banach spaces}}, doi = {10.1017/s0143385705000714}, volume = {26}, year = {2006}, } @inproceedings{8515, abstract = {We consider the evolution of a set carried by a space periodic incompressible stochastic flow in a Euclidean space. We report on three main results obtained in [8, 9, 10] concerning long time behaviour for a typical realization of the stochastic flow. First, at time t most of the particles are at a distance of order √t away from the origin. Moreover, we prove a Central Limit Theorem for the evolution of a measure carried by the flow, which holds for almost every realization of the flow. Second, we show the existence of a zero measure full Hausdorff dimension set of points, which escape to infinity at a linear rate. Third, in the 2-dimensional case, we study the set of points visited by the original set by time t. Such a set, when scaled down by the factor of t, has a limiting non random shape.}, author = {Kaloshin, Vadim and DOLGOPYAT, D. and KORALOV, L.}, booktitle = {XIVth International Congress on Mathematical Physics}, isbn = {9789812562012}, location = {Lisbon, Portugal}, pages = {290--295}, publisher = {World Scientific}, title = {{Long time behaviour of periodic stochastic flows}}, doi = {10.1142/9789812704016_0026}, year = {2006}, } @article{868, abstract = {Background: The glyoxylate cycle is thought to be present in bacteria, protists, plants, fungi, and nematodes, but not in other Metazoa. However, activity of the glyoxylate cycle enzymes, malate synthase (MS) and isocitrate lyase (ICL), in animal tissues has been reported. In order to clarify the status of the MS and ICL genes in animals and get an insight into their evolution, we undertook a comparative-genomic study. Results: Using sequence similarity searches, we identified MS genes in arthropods, echinoderms, and vertebrates, including platypus and opossum, but not in the numerous sequenced genomes of placental mammals. The regions of the placental mammals' genomes expected to code for malate synthase, as determined by comparison of the gene orders in vertebrate genomes, show clear similarity to the opossum MS sequence but contain stop codons, indicating that the MS gene became a pseudogene in placental mammals. By contrast, the ICL gene is undetectable in animals other than the nematodes that possess a bifunctional, fused ICL-MS gene. Examination of phylogenetic trees of MS and ICL suggests multiple horizontal gene transfer events that probably went in both directions between several bacterial and eukaryotic lineages. The strongest evidence was obtained for the acquisition of the bifunctional ICL-MS gene from an as yet unknown bacterial source with the corresponding operonic organization by the common ancestor of the nematodes. Conclusion: The distribution of the MS and ICL genes in animals suggests that either they encode alternative enzymes of the glyoxylate cycle that are not orthologous to the known MS and ICL or the animal MS acquired a new function that remains to be characterized. Regardless of the ultimate solution to this conundrum, the genes for the glyoxylate cycle enzymes present a remarkable variety of evolutionary events including unusual horizontal gene transfer from bacteria to animals.}, author = {Fyodor Kondrashov and Koonin, Eugene V and Morgunov, Igor G and Finogenova, Tatiana V and Kondrashova, Marie N}, journal = {Biology Direct}, publisher = {BioMed Central}, title = {{Evolution of glyoxylate cycle enzymes in Metazoa Evidence of multiple horizontal transfer events and pseudogene formation}}, doi = {10.1186/1745-6150-1-31}, volume = {1}, year = {2006}, } @article{873, abstract = {New genes commonly appear through complete or partial duplications of pre-existing genes. Duplications of long DNA segments are constantly produced by rare mutations, may become fixed in a population by selection or random drift, and are subject to divergent evolution of the paralogous sequences after fixation, although gene conversion can impede this process. New data shed some light on each of these processes. Mutations which involve duplications can occur through at least two different mechanisms, backward strand slippage during DNA replication and unequal crossing-over. The background rate of duplication of a complete gene in humans is 10-9-10-10 per generation, although many genes located within hot-spots of large-scale mutation are duplicated much more often. Many gene duplications affect fitness strongly, and are responsible, through gene dosage effects, for a number of genetic diseases. However, high levels of intrapopulation polymorphism caused by presence or absence of long, gene-containing DNA segments imply that some duplications are not under strong selection. The polymorphism to fixation ratios appear to be approximately the same for gene duplications and for presumably selectively neutral nucleotide substitutions, which, according to the McDonald-Kreitman test, is consistent with selective neutrality of duplications. However, this pattern can also be due to negative selection against most of segregating duplications and positive selection for at least some duplications which become fixed. Patterns in post-fixation evolution of duplicated genes do not easily reveal the causes of fixations. Many gene duplications which became fixed recently in a variety of organisms were positively selected because the increased expression of the corresponding genes was beneficial. The effects of gene dosage provide a unified framework for studying all phases of the life history of a gene duplication. Application of well-known methods of evolutionary genetics to accumulating data on new, polymorphic, and fixed duplication will enhance our understanding of the role of natural selection in the evolution by gene duplication.}, author = {Fyodor Kondrashov and Kondrashov, Alexey S}, journal = {Journal of Theoretical Biology}, number = {2}, pages = {141 -- 151}, publisher = {Elsevier}, title = {{Role of selection in fixation of gene duplications}}, doi = {10.1016/j.jtbi.2005.08.033}, volume = {239}, year = {2006}, } @article{903, abstract = {Background: Carcinogenesis typically involves multiple somatic mutations in caretaker (DNA repair) and gatekeeper (tumor suppressors and oncogenes) genes. Analysis of mutation spectra of the tumor suppressor that is most commonly mutated in human cancers, p53, unexpectedly suggested that somatic evolution of the p53 gene during tumorigenesis is dominated by positive selection for gain of function. This conclusion is supported by accumulating experimental evidence of evolution of new functions of p53 in tumors. These findings prompted a genome-wide analysis of possible positive selection during tumor evolution. Methods: A comprehensive analysis of probable somatic mutations in the sequences of Expressed Sequence Tags (ESTs) from malignant tumors and normal tissues was performed in order to access the prevalence of positive selection in cancer evolution. For each EST, the numbers of synonymous and non-synonymous substitutions were calculated. In order to identify genes with a signature of positive selection in cancers, these numbers were compared to: i) expected numbers and ii) the numbers for the respective genes in the ESTs from normal tissues. Results: We identified 112 genes with a signature of positive selection in cancers, i.e., a significantly elevated ratio of non-synonymous to synonymous substitutions, in tumors as compared to 37 such genes in an approximately equal-sized EST collection from normal tissues. A substantial fraction of the tumor-specific positive-selection candidates have experimentally demonstrated or strongly predicted links to cancer. Conclusion: The results of EST analysis should be interpreted with extreme caution given the noise introduced by sequencing errors and undetected polymorphisms. Furthermore, an inherent limitation of EST analysis is that multiple mutations amenable to statistical analysis can be detected only in relatively highly expressed genes. Nevertheless, the present results suggest that positive selection might affect a substantial number of genes during tumorigenic somatic evolution.}, author = {Babenko, Vladimir N and Basu, Malay K and Fyodor Kondrashov and Rogozin, Igor B and Koonin, Eugene V}, journal = {BMC Cancer}, publisher = {BioMed Central}, title = {{Signs of positive selection of somatic mutations in human cancers detected by EST sequence analysis}}, doi = {10.1186/1471-2407-6-36}, volume = {6}, year = {2006}, } @article{9505, abstract = {Cytosine methylation, a common form of DNA modification that antagonizes transcription, is found at transposons and repeats in vertebrates, plants and fungi. Here we have mapped DNA methylation in the entire Arabidopsis thaliana genome at high resolution. DNA methylation covers transposons and is present within a large fraction of A. thaliana genes. Methylation within genes is conspicuously biased away from gene ends, suggesting a dependence on RNA polymerase transit. Genic methylation is strongly influenced by transcription: moderately transcribed genes are most likely to be methylated, whereas genes at either extreme are least likely. In turn, transcription is influenced by methylation: short methylated genes are poorly expressed, and loss of methylation in the body of a gene leads to enhanced transcription. Our results indicate that genic transcription and DNA methylation are closely interwoven processes.}, author = {Zilberman, Daniel and Gehring, Mary and Tran, Robert K. and Ballinger, Tracy and Henikoff, Steven}, issn = {1546-1718}, journal = {Nature Genetics}, number = {1}, pages = {61--69}, publisher = {Nature Publishing Group}, title = {{Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription}}, doi = {10.1038/ng1929}, volume = {39}, year = {2006}, } @article{6151, author = {Salecker, Iris and Häusser, Michael and de Bono, Mario}, issn = {1469-221X}, journal = {EMBO reports}, number = {6}, pages = {585--589}, publisher = {Wiley}, title = {{On the axonal road to circuit function and behaviour: Workshop on the assembly and function of neuronal circuits}}, doi = {10.1038/sj.embor.7400713}, volume = {7}, year = {2006}, } @article{6152, author = {Rogers, Candida and Persson, Annelie and Cheung, Benny and de Bono, Mario}, issn = {0960-9822}, journal = {Current Biology}, number = {7}, pages = {649--659}, publisher = {Elsevier}, title = {{Behavioral motifs and neural pathways coordinating O2 responses and aggregation in C. elegans}}, doi = {10.1016/j.cub.2006.03.023}, volume = {16}, year = {2006}, } @inproceedings{7326, abstract = {Often the properties of a single cell are considered as representative for a complete polymer electrolyte fuel cell stack or even a fuel cell system. In some cases this comes close, however, in many real cases differences on several scales become important. Cell interaction phenomena in fuel cell stacks that arise from inequalities between adjacent cells are investigated in detail experimentally. For that, a specialized 2-cell stack with advanced localized diagnostics was developed. The results show that inequalities propagate by electrical coupling, inhomogeneous cell polarization and inducing in-plane current in the common bipolar plate. The effects of the different loss-mechanisms are analyzed and quantified. }, author = {Büchi, Felix N. and Freunberger, Stefan Alexander and Santis, Marco}, booktitle = {ECS Transactions}, location = {Cancun, Mexico}, number = {1}, pages = {963--968}, publisher = {ECS}, title = {{What is learned beyond the scale of single cells?}}, doi = {10.1149/1.2356215}, volume = {3}, year = {2006}, } @article{7327, abstract = {Propagation of performance changes to adjacent cells in polymer electrolyte fuel cell stacks is studied by means of voltage monitoring and local current density measurements in peripheral cells of the stack. A technical fuel cell stack has been modified by implementing two independent reactant and coolant supplies in order to deliberately change the performance of one cell (anomalous cell) and study the coupling phenomena to adjacent cells (coupling cells), while keeping the working conditions of the later cell-group unaltered. Two anomalies are studied: (i) air starvation and (ii) thermal anomaly, in a single anomalous cell in the stack and their coupling to adjacent cells. The results have shown that anomalies inducing considerable changes in the local current density of the anomalous cell (such as air starvation) propagate to adjacent cells affecting their performance. The propagation of local current density changes takes place via the common bipolar plate due to its finite thickness and in-plane conductivity. Consequently, anomalies which do not strongly influence the local current density distribution (such as a thermal anomaly under the studied working conditions) do not propagate to adjacent cells.}, author = {Santis, Marco and Freunberger, Stefan Alexander and Papra, Matthias and Wokaun, Alexander and Büchi, Felix N.}, issn = {0378-7753}, journal = {Journal of Power Sources}, number = {2}, pages = {1076--1083}, publisher = {Elsevier}, title = {{Experimental investigation of coupling phenomena in polymer electrolyte fuel cell stacks}}, doi = {10.1016/j.jpowsour.2006.06.007}, volume = {161}, year = {2006}, } @article{7328, abstract = {An experimental technique for measuring the current density distribution with a resolution smaller than the channel/rib scale of the flow field in polymer electrolyte fuel cells (PEFCs) is presented. The electron conductors in a plane perpendicular to the channel direction are considered as two-dimensional resistors. Hence, the current density is obtained from the solution of Laplace's equation with the potentials at current collector and reaction layer as boundary conditions. Using ohmic drop for calculating the local current, detailed knowledge of all resistances involved is of prime importance. In particular, the contact resistance between the gas diffusion layer (GDL) and flow field rib, as well as GDL bulk conductivity, are strongly dependent on clamping pressure. They represent a substantial amount of the total ohmic drop and therefore require careful consideration. The detailed experimental setup as well as the concise procedure for quantitative data evaluation is described. Finally, the method is applied successfully to a cell operated on pure oxygen and air up to high current densities. The results show that electrical and ionic resistances seem to govern the current distribution at low current regimes, whereas mass transport limitations locally hamper the current production at high loads.}, author = {Freunberger, Stefan Alexander and Reum, Mathias and Evertz, Jörg and Wokaun, Alexander and Büchi, Felix N.}, issn = {0013-4651}, journal = {Journal of The Electrochemical Society}, number = {11}, publisher = {The Electrochemical Society}, title = {{Measuring the current distribution in PEFCs with sub-millimeter resolution}}, doi = {10.1149/1.2345591}, volume = {153}, year = {2006}, } @article{7329, abstract = {A novel measurement principle for measuring the current distribution in polymer electrolyte fuel cells (PEFCs) is introduced. It allows, in contrast to all other known techniques, for the first time for a resolution smaller than the channel/rib scale of the flow field in PEFCs. The current density is obtained by considering the electron conductors in the cell as a two-dimensional resistor with the voltage drop caused by the current. The method was applied to a cell operated on oxygen up to high current densities. The results show that the ohmic resistances govern the current distribution in the low current regime, whereas mass transport limitations hamper the current production under the land at high loads.}, author = {Freunberger, Stefan Alexander and Reum, Mathias and Wokaun, Alexander and Büchi, Felix N.}, issn = {1388-2481}, journal = {Electrochemistry Communications}, number = {9}, pages = {1435--1438}, publisher = {Elsevier}, title = {{Expanding current distribution measurement in PEFCs to sub-millimeter resolution}}, doi = {10.1016/j.elecom.2006.05.032}, volume = {8}, year = {2006}, } @article{7330, abstract = {Polymer electrolyte fuel cells (PE fuel cells) working with air at low stoichiometries (<2.0) and standard electrochemical components show a high degree of inhomogeneity in the current density distribution over the active area. An inhomogeneous current density distribution leads to a non-uniform utilization of the active area, which could negatively affect the time of life of the cells. Furthermore, it is also believed to lower cell performance. In this work, the homogenization of the current density, realized by means of tailored cathodes with along-the-air-channel redistributed catalyst loadings, is investigated. The air stoichiometry range for which a homogenization of the current density is achieved depends upon the gradient with which the catalyst is redistributed along the air channel. A gentle increasing catalyst loading profile homogenizes the current density at relatively higher air stoichiometries, while a steeper profile is suited better for lower air stoichiometries. The results show that a homogenization of the current density by means of redistributed catalyst loading has negative effects on cell performance. Model calculations corroborate the experimental findings on homogenization of the current density and deliver an explanation for the decrease in cell performance.}, author = {Santis, M. and Freunberger, Stefan Alexander and Reiner, A. and Büchi, F.N.}, issn = {0013-4686}, journal = {Electrochimica Acta}, number = {25}, pages = {5383--5393}, publisher = {Elsevier}, title = {{Homogenization of the current density in polymer electrolyte fuel cells by in-plane cathode catalyst gradients}}, doi = {10.1016/j.electacta.2006.02.008}, volume = {51}, year = {2006}, } @article{7331, abstract = {A previously developed mathematical model for water management and current density distribution in a polymer electrolyte fuel cell (PEFCs) is employed to investigate the effects of cooling strategies on cell performance. The model describes a two-dimensional slice through the cell along the channels and through the entire cell sandwich including the coolant channels and the bipolar plate. Arbitrary flow arrangements of fuel, oxidant, and coolant stream directions can be described. Due to the serious impact of temperature on all processes in the PEFC, both the relative direction of the coolant stream to the gas streams and its mass flow turns out to significantly affect the cell performance. Besides influencing the electrochemical reaction and all kinds of mass transfer temperature, variations predominantly alter the local membrane hydration distribution and subseqently its conductivity.}, author = {Freunberger, Stefan Alexander and Wokaun, Alexander and Büchi, Felix N.}, issn = {0013-4651}, journal = {Journal of The Electrochemical Society}, number = {5}, publisher = {The Electrochemical Society}, title = {{In-plane effects in large-scale PEFCs: II. The influence of cooling strategy on cell performance}}, doi = {10.1149/1.2185282}, volume = {153}, year = {2006}, }