@article{18529, abstract = {Temporal networks are obtained from time-dependent interactions among individuals, whereas the interactions can be emails, phone calls, face-to-face meetings, or work collaboration. In this article, a temporal game framework is established, in which interactions among rational individuals are embedded into two-player games in a time-dependent manner. This allows studying the time-dependent complexity and variability of interactions, and the way they affect prosocial behaviors. Based on this simple mathematical model, it is found that the level of cooperation is promoted when the time of collaboration is equally limited for every individual. This observation is confirmed by a series of systematic human experiments on over 1,400 subjects, forming a foundation for comprehensively describing human temporal interactions in collaboration. The research results reveal an important incentive for human cooperation, leading to a better understanding of a fascinating aspect of human nature in society.}, author = {Zhang, Yichao and Wang, Jiasheng and Wen, Guanghui and Guan, Jihong and Zhou, Shuigeng and Chen, Guanrong and Chatterjee, Krishnendu and Perc, Matjaz}, issn = {2327-4697}, journal = {IEEE Transactions on Network Science and Engineering}, number = {1}, pages = {4--12}, publisher = {IEEE}, title = {{Limitation of time promotes cooperation in structured collaboration systems}}, doi = {10.1109/TNSE.2024.3481434}, volume = {12}, year = {2025}, } @article{18558, abstract = {The current investigation presents a facile and cost-effective sol-gel approach for the synthesis of phase-pure multiferroic bismuth ferrite (BiFeO3) nanoparticles (BFO NPs) by using propylene glycol as a complexing agent, intended for use as a photocatalyst to efficiently degrade organic dyes in aqueous solutions under natural sunlight. Characterization techniques, including thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD), elucidated a plausible reaction pathway for the formation of phase-pure BFO NPs. Rietveld refinement of the XRD data, in conjunction with transmission electron microscopy (TEM) and Raman spectroscopy, confirmed the synthesis of single-phase BFO NPs at 400 °C, displaying a space group of R3c and an average crystallite size of 25 nm. UV–visible diffuse reflectance spectroscopy revealed an absorption cut-off wavelength near 590 nm, corresponding to a band gap of 2.08 eV, indicating the capability of BFO NPs to absorb visible light within the 400–590 nm range. BFO NPs have shown efficient and rapid photocatalytic degradation of methylene blue (MB) in acidic, neutral, and basic pH conditions under natural sunlight. This is attributed to the intrinsic ferroelectric and ferromagnetic ordering present in synthesized BFO NPs which facilitates the separation and migration of photoinduced charges through band bending phenomena at the interface.}, author = {Verma, Madhu and Kumar, Ajay and Thakur, Vijay Kumar and Maurya, Akanksha and Kumar, Sachin and Singh, Saurabh and Srivastav, Simant Kumar}, issn = {1573-4846}, journal = {Journal of Sol-Gel Science and Technology}, pages = {356--373}, publisher = {Springer Nature}, title = {{Efficient and rapid sunlight-driven photocatalytic degradation of methylene blue dye using multiferroic BiFeO3 nanoparticles}}, doi = {10.1007/s10971-024-06607-2}, volume = {113}, year = {2025}, } @article{18565, abstract = {We present a computational approach for unfolding 3D shapes isometrically into the plane as a single patch without overlapping triangles. This is a hard, sometimes impossible, problem, which existing methods are forced to soften by allowing for map distortions or multiple patches. Instead, we propose a geometric relaxation of the problem: We modify the input shape until it admits an overlap‐free unfolding. We achieve this by locally displacing vertices and collapsing edges, guided by the unfolding process. We validate our algorithm quantitatively and qualitatively on a large dataset of complex shapes and show its proficiency by fabricating real shapes from paper.}, author = {Bhargava, Manas and Schreck, Camille and Freire, M. and Hugron, P. A. and Lefebvre, S. and Sellán, S. and Bickel, Bernd}, issn = {1467-8659}, journal = {Computer Graphics Forum}, keywords = {fabrication, single patch unfolding, mesh simplification}, number = {1}, publisher = {Wiley}, title = {{Mesh simplification for unfolding}}, doi = {10.1111/cgf.15269}, volume = {44}, year = {2025}, } @article{18580, abstract = {Motivated by the study of recurrent orbits and dynamics within a Morse set of a Morse decomposition we introduce the concept of Morse predecomposition of an isolated invariant set within the setting of both combinatorial and classical dynamical systems. While Morse decomposition summarizes solely the gradient part of a dynamical system, the developed generalization extends to the recurrent component as well. In particular, a chain recurrent set, which is indecomposable in terms of Morse decomposition, can be represented more finely in the Morse predecomposition framework. This generalization is achieved by forgoing the poset structure inherent to Morse decomposition and relaxing the notion of connection between Morse sets (elements of Morse decomposition) in favor of what we term ’links’. We prove that a Morse decomposition is a special case of Morse predecomposition indexed by a poset. Additionally, we show how a Morse predecomposition may be condensed back to retrieve a Morse decomposition.}, author = {Lipiński, Michał and Mischaikow, Konstantin and Mrozek, Marian}, issn = {1662-3592}, journal = {Qualitative Theory of Dynamical Systems}, number = {1}, publisher = {Springer Nature}, title = {{Morse predecomposition of an invariant set}}, doi = {10.1007/s12346-024-01144-3}, volume = {24}, year = {2025}, } @article{18605, abstract = {The response of clouds and moist-convective processes to heat loss to space by long-wave radiative cooling is an important feedback in the Earth's atmosphere. It is known that moist convection increases roughly in equilibrium with radiative cooling, an assumption often made in simplified models of the tropical atmosphere. In this study, we use an idealised two-dimensional model of the atmosphere introduced by Vallis et. al. and incorporate a bulk-cooling term, which is an idealisation of radiative cooling in the atmosphere. We comment briefly on the static stability of the system to dry and moist convection and characteris its moist convective response to changes in the bulk cooling. We find that, while the clear-sky regions of the model respond directly to the change in the cooling term, the regions dominated by moist convective plumes are insensitive to changes in cooling. Similar to previous findings from cloud-resolving models, we too find in our idealised setting that the majority of the increase in convection occurs via an increase in the areal coverage of convection, rather than its intensity. We argue that these small-scale convective processes are an upper bound on how quickly convective intensity can change to stay in equilibrium with radiative cooling.}, author = {Agasthya, Lokahith N and Muller, Caroline J and Cheve, Mathis}, issn = {1477-870X}, journal = {Quarterly Journal of the Royal Meteorological Society}, number = {766}, publisher = {Wiley}, title = {{Moist convective scaling: Insights from an idealised model}}, doi = {10.1002/qj.4902}, volume = {151}, year = {2025}, } @article{18619, abstract = {Brassinosteroids (BRs) are steroidal phytohormones indispensable for plant growth, development, and responses to environmental stresses. The export of bioactive BRs to the apoplast is essential for BR signalling initiation, which requires binding of BR molecule to the extracellular domains of the plasma membrane-localized receptor complex. We have previously shown that the Arabidopsis thaliana ATP-binding cassette (ABC) transporter, ABCB19, functions as a BR exporter, and together with its close homologue, ABCB1, positively regulate BR signalling. Here, we demonstrate that ABCB1 is another BR transporter. The ATP hydrolysis activity of ABCB1 was stimulated by bioactive BRs, and its transport activity was confirmed in proteoliposomes and protoplasts. Structures of ABCB1 in substrate-unbound (apo), brassinolide (BL)-bound, and ATP plus BL-bound states were determined. In the BL-bound structure, BL was bound to the hydrophobic cavity formed by the transmembrane domain, and triggered local conformational changes. Together, our data provide additional insights into the ABC transporter-mediated BR export.}, author = {Wei, H and Zhu, H and Ying, W and Janssens, H and Kvasnica, M and Winne, JM and Gao, Y and Friml, Jiří and Ma, Q and Tan, S and Liu, X and Russinova, E and Sun, L}, issn = {2590-3462}, journal = {Plant Communications}, number = {1}, publisher = {Elsevier}, title = {{Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1}}, doi = {10.1016/j.xplc.2024.101181}, volume = {6}, year = {2025}, } @article{18626, abstract = {The local angle property of the (order-1) Delaunay triangulations of a generic set in R2 asserts that the sum of two angles opposite a common edge is less than π. This paper extends this property to higher order and uses it to generalize two classic properties from order-1 to order-2: (1) among the complete level-2 hypertriangulations of a generic point set in R2, the order-2 Delaunay triangulation lexicographically maximizes the sorted angle vector; (2) among the maximal level-2 hypertriangulations of a generic point set in R2, the order-2 Delaunay triangulation is the only one that has the local angle property. We also use our method of establishing (2) to give a new short proof of the angle vector optimality for the (order-1) Delaunay triangulation. For order-1, both properties have been instrumental in numerous applications of Delaunay triangulations, and we expect that their generalization will make order-2 Delaunay triangulations more attractive to applications as well.}, author = {Edelsbrunner, Herbert and Garber, Alexey and Saghafian, Morteza}, issn = {1090-2082}, journal = {Advances in Mathematics}, publisher = {Elsevier}, title = {{Order-2 Delaunay triangulations optimize angles}}, doi = {10.1016/j.aim.2024.110055}, volume = {461}, year = {2025}, } @article{18631, abstract = {Within the established framework of structure formation, galaxies start as systems of low stellar mass and gradually grow into far more massive galaxies. The existence of massive galaxies in the first billion years of the Universe, as suggested by recent observations, seems to challenge this model, as such galaxies would require highly efficient conversion of baryons into stars. An even greater challenge in this epoch is the existence of massive galaxies that have already ceased forming stars. However, robust detections of early massive quiescent galaxies have been challenging due to the coarse wavelength sampling of photometric surveys. Here we report the spectroscopic confirmation with the James Webb Space Telescope of the quiescent galaxy RUBIES-EGS-QG-1 at redshift z = 4.90, 1.2 billion years after the Big Bang. Deep stellar absorption features in the spectrum reveal that the stellar mass of the galaxy of 1011 M⊙ formed in a short 200 Myr burst of star formation, after which star formation activity dropped rapidly and persistently. According to current galaxy formation models, systems with such rapid stellar mass growth and early quenching are too rare to plausibly occur in the small area probed spectroscopically with JWST. Instead, the discovery of RUBIES-EGS-QG-1 implies that early massive quiescent galaxies can be quenched earlier or exhaust gas available for star formation more efficiently than assumed at present.}, author = {De Graaff, Anna and Setton, David J. and Brammer, Gabriel and Cutler, Sam and Suess, Katherine A. and Labbé, Ivo and Leja, Joel and Weibel, Andrea and Maseda, Michael V. and Whitaker, Katherine E. and Bezanson, Rachel and Boogaard, Leindert A. and Cleri, Nikko J. and De Lucia, Gabriella and Franx, Marijn and Greene, Jenny E. and Hirschmann, Michaela and Matthee, Jorryt J and Mcconachie, Ian and Naidu, Rohan P. and Oesch, Pascal A. and Price, Sedona H. and Rix, Hans Walter and Valentino, Francesco and Wang, Bingjie and Williams, Christina C.}, issn = {2397-3366}, journal = {Nature Astronomy}, pages = {280--292}, publisher = {Springer Nature}, title = {{Efficient formation of a massive quiescent galaxy at redshift 4.9}}, doi = {10.1038/s41550-024-02424-3}, volume = {9}, year = {2025}, } @article{18632, abstract = {For an arbitrary dimension (Formula presented.), we study: the polyharmonic Gaussian field (Formula presented.) on the discrete torus (Formula presented.), that is the random field whose law on (Formula presented.) given by (Formula presented.) where (Formula presented.) is the Lebesgue measure and (Formula presented.) is the discrete Laplacian; the associated discrete Liouville quantum gravity (LQG) measure associated with it, that is, the random measure on (Formula presented.) (Formula presented.) where (Formula presented.) is a regularity parameter. As (Formula presented.), we prove convergence of the fields (Formula presented.) to the polyharmonic Gaussian field (Formula presented.) on the continuous torus (Formula presented.), as well as convergence of the random measures (Formula presented.) to the LQG measure (Formula presented.) on (Formula presented.), for all (Formula presented.). }, author = {Dello Schiavo, Lorenzo and Herry, Ronan and Kopfer, Eva and Sturm, Karl Theodor}, issn = {1522-2616}, journal = {Mathematische Nachrichten}, number = {1}, pages = {244--281}, publisher = {Wiley}, title = {{Polyharmonic fields and Liouville quantum gravity measures on tori of arbitrary dimension: From discrete to continuous}}, doi = {10.1002/mana.202400169}, volume = {298}, year = {2025}, } @misc{18697, abstract = {The information-processing capability of the brain’s cellular network depends on the physical wiring pattern between neurons and their molecular and functional characteristics. Mapping neurons and resolving their individual synaptic connections can be achieved by volumetric imaging at nanoscale resolution with dense cellular labelling. Light microscopy is uniquely positioned to visualize specific molecules but dense, synapse-level circuit reconstruction by light microscopy has been out of reach due to limitations in resolution, contrast, and volumetric imaging capability. Here we developed light-microscopy based connectomics (LICONN). We integrated specifically engineered hydrogel embedding and expansion with comprehensive deep-learning based segmentation and analysis of connectivity, thus directly incorporating molecular information in synapse-level brain tissue reconstructions. LICONN will allow synapse-level brain tissue phenotyping in biological experiments in a readily adoptable manner.}, author = {Danzl, Johann G and Lyudchik, Julia and Kreuzinger, Caroline}, publisher = {Institute of Science and Technology Austria}, title = {{Light-microscopy based connectomic reconstruction of mammalian brain tissue}}, doi = {10.15479/AT:ISTA:18697}, year = {2025}, } @article{18701, abstract = {We developed in-situ engineered polycrystalline polythiophene (PTh) and its composite with reduced graphene oxide (PTh-rGO) via a simple chemical synthesis. The PTh-rGO-based electrodes in a symmetrical device with xanthan gum in 1 M aq. Na2SO4 as an electrolyte, delivers a specific capacitance (Csp) of 114.7 F g–1 (electrode) and 28.7 F g–1 (cell) at an applied current density of 0.2 A g−1. The maximum energy and power densities recorded from the device were 588.0 mWh kg−1 and 1.1 kW kg−1 at 1.5 A g−1. The device exhibited a remarkable retention of Csp of 98.9 % over 10,000 continuous galvanostatic charge–discharge cycles highlighting an excellent performance. Electrochemical impedance spectroscopy analysis emphasizes material’s excellent structural integrity. This is attributed to the crystalline phases present in the matrix.}, author = {Mahato, Neelima and Singh, Saurabh and Sreekanth, T. V.M. and Yoo, Kisoo and Kim, Jonghoon}, issn = {1873-4979}, journal = {Materials Letters}, publisher = {Elsevier}, title = {{In-situ engineered highly-crystalline Polythiophene empowered electrochemical capacitor-II: Anomalous electrochemical charge storage behavior of Polythiophene-rGO composite}}, doi = {10.1016/j.matlet.2024.137869}, volume = {382}, year = {2025}, } @article{18705, abstract = {Given a non-singular diagonal cubic hypersurface X⊂Pn−1 over Fq(t) with char(Fq)≠3, we show that the number of rational points of height at most |P| is O(|P|3+ε) for n=6 and O(|P|2+ε) for n=4. In fact, if n=4 and char(Fq)>3 we prove that the number of rational points away from any rational line contained in X is bounded by O(|P|3/2+ε). From the result in 6 variables we deduce weak approximation for diagonal cubic hypersurfaces for n≥7 over Fq(t) when char(Fq)>3 and handle Waring's problem for cubes in 7 variables over Fq(t) when char(Fq)≠3. Our results answer a question of Davenport regarding the number of solutions of bounded height to x31+x32+x33=x34+x35+x36 with xi∈Fq[t].}, author = {Glas, Jakob and Hochfilzer, Leonhard}, issn = {1432-1807}, journal = {Mathematische Annalen}, pages = {5485--5533}, publisher = {Springer Nature}, title = {{On a question of Davenport and diagonal cubic forms over Fq(t)}}, doi = {10.1007/s00208-024-03035-z}, volume = {391}, year = {2025}, } @article{18707, abstract = {Lead Sulfide (PbS) has garnered attention as a promising thermoelectric (TE) material due to its natural abundance and cost-effectiveness. However, its practical application is hindered by inherently high lattice thermal conductivity and low electrical conductivity. In this study, we address these challenges by surface functionalization of PbS nanocrystals using Cu2S molecular complexes-based ligand displacement. The molecular complexes facilitate the incorporation of Cu into the PbS matrix and leads to the formation of nanoscale defects, dislocations, and strain fields while optimizing the charge carrier transport. The structural modulations enhance the phonon scattering and lead to a significant reduction in lattice thermal conductivity of 0.60 W m−1K−1 at 867 K in the PbS-Cu2S system. Simultaneously, the Cu incorporation improves electrical conductivity by increasing both carrier concentration and mobility with carefully optimized the content of Cu2S molecular complexes. These synergistic modifications yield a peak figure-of-merit (zT) of 1.05 at 867 K for the PbS-1.0 %Cu2S sample, representing an almost twofold enhancement in TE performance compared to pristine PbS. This work highlights the effectiveness of surface treatment in overcoming the intrinsic limitations of PbS-based materials and presents a promising strategy for the development of high-efficiency TE systems.}, author = {Shu, Haibo and Zhao, Mingjun and Lu, Shaoqing and Wan, Shanhong and Genç, Aziz and Huang, Lulu and Ibáñez, Maria and Lim, Khak Ho and Hong, Min and Liu, Yu}, issn = {1095-7103}, journal = {Journal of Colloid and Interface Science}, pages = {703--712}, publisher = {Elsevier}, title = {{Influence of surface engineering on the transport properties of lead sulfide nanomaterials}}, doi = {10.1016/j.jcis.2024.12.067}, volume = {683}, year = {2025}, } @article{18710, abstract = {We present an ab initio theoretical method to calculate the resonant Auger spectrum in the presence of ultrafast dissociation. The method is demonstrated by deriving the L-VV resonant Auger spectrum mediated by the 2p3/2−1σ* resonance in HCl, where the electronic Auger decay and nuclear dissociation occur on the same time scale. The Auger decay rates are calculated within the one-center approximation and are shown to vary significantly with the inter-nuclear distance. A quantum-mechanical description of dissociation is effectuated by propagating the corresponding Franck–Condon factors. The calculated profiles of Auger spectral lines resemble those of atomic Auger decay but here the characteristic tails extend towards lower electron kinetic energies, which reflect specific features of the potential energy curves. The presented method can describe the resonant Auger spectrum for an arbitrary speed of dissociation and simplifies to known approximations in the limiting cases.}, author = {Hrast, Mateja and Ljubotina, Marko and Zitnik, Matjaz}, issn = {1463-9076}, journal = {Physical Chemistry Chemical Physics}, number = {3}, pages = {1473--1482}, publisher = {Royal Society of Chemistry}, title = {{Ab initio Auger spectrum of the ultrafast dissociating 2p3/2−1σ* resonance in HCl}}, doi = {10.1039/d4cp03727h}, volume = {27}, year = {2025}, } @misc{18712, abstract = {This file contains the code associated with the manuscript 'Effect of assortative mating and sexual selection on polygenic barriers to gene flow'. }, author = {Surendranadh, Parvathy and Sachdeva, Himani}, publisher = {Institute of Science and Technology Austria}, title = {{Mathematica notebook and Fortran code for 'Effect of assortative mating and sexual selection on polygenic barriers to gene flow'}}, doi = {10.15479/AT:ISTA:17344}, year = {2025}, } @article{18753, abstract = {We continue a line of research which studies which hereditary families of digraphs have bounded dichromatic number. For a class of digraphs C, a hero in C is any digraph H such that H -free digraphs in C have bounded dichromatic number. We show that if F is an oriented star of degree at least five, the only heroes for the class of F -free digraphs are transitive tournaments. For oriented stars F of degree exactly four, we show the only heroes in F -free digraphs are transitive tournaments, or possibly special joins of transitive tournaments. Aboulker et al. characterized the set of heroes of {H,K1+P2→} -free digraphs almost completely, and we show the same characterization for the class of {H,rK1+P3→} -free digraphs. Lastly, we show that if we forbid two "valid" orientations of brooms, then every transitive tournament is a hero for this class of digraphs.}, author = {Carbonero, Alvaro and Koerts, Hidde and Moore, Benjamin and Spirkl, Sophie}, issn = {0195-6698}, journal = {European Journal of Combinatorics}, publisher = {Elsevier}, title = {{On heroes in digraphs with forbidden induced forests}}, doi = {10.1016/j.ejc.2024.104104}, volume = {125}, year = {2025}, } @article{18754, abstract = {Exploring the molecular correlates of metabolic health measures may identify their shared and unique biological processes and pathways. Molecular proxies of these traits may also provide a more objective approach to their measurement. Here, DNA methylation (DNAm) data were used in epigenome-wide association studies (EWASs) and for training epigenetic scores (EpiScores) of six metabolic traits: body mass index (BMI), body fat percentage, waist-hip ratio, and blood-based measures of glucose, high-density lipoprotein cholesterol, and total cholesterol in >17,000 volunteers from the Generation Scotland (GS) cohort. We observed a maximum of 12,033 significant findings (p < 3.6 × 10−8) for BMI in a marginal linear regression EWAS. By contrast, a joint and conditional Bayesian penalized regression approach yielded 27 high-confidence associations with BMI. EpiScores trained in GS performed well in both Scottish and Singaporean test cohorts (Lothian Birth Cohort 1936 [LBC1936] and Health for Life in Singapore [HELIOS]). The EpiScores for BMI and total cholesterol performed best in HELIOS, explaining 20.8% and 7.1% of the variance in the measured traits, respectively. The corresponding results in LBC1936 were 14.4% and 3.2%, respectively. Differences were observed in HELIOS for body fat, where the EpiScore explained ∼9% of the variance in Chinese and Malay -subgroups but ∼3% in the Indian subgroup. The EpiScores also correlated with cognitive function in LBC1936 (standardized βrange: 0.08–0.12, false discovery rate p [pFDR] < 0.05). Accounting for the correlation structure across the methylome can vastly affect the number of lead findings in EWASs. The EpiScores of metabolic traits are broadly applicable across populations and can reflect differences in cognition.}, author = {Smith, Hannah M. and Ng, Hong Kiat and Moodie, Joanna E. and Gadd, Danni A. and Mccartney, Daniel L. and Bernabeu, Elena and Campbell, Archie and Redmond, Paul and Taylor, Adele and Page, Danielle and Corley, Janie and Harris, Sarah E. and Tay, Darwin and Deary, Ian J. and Evans, Kathryn L. and Robinson, Matthew Richard and Chambers, John C. and Loh, Marie and Cox, Simon R. and Marioni, Riccardo E. and Hillary, Robert F.}, issn = {1537-6605}, journal = {American Journal of Human Genetics}, number = {1}, pages = {106--115}, publisher = {Elsevier}, title = {{DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts}}, doi = {10.1016/j.ajhg.2024.11.012}, volume = {112}, year = {2025}, } @article{18764, abstract = {We prove that a class of weakly perturbed Hamiltonians of the form H_λ= H_0 + λW, with W being a Wigner matrix, exhibits prethermalization. That is, the time evolution generated by H_λ relaxes to its ultimate thermal state via an intermediate prethermal state with a lifetime of order λ^{-2}. Moreover, we obtain a general relaxation formula, expressing the perturbed dynamics via the unperturbed dynamics and the ultimate thermal state. The proof relies on a two-resolvent law for the deformed Wigner matrix H_λ.}, author = {Erdös, László and Henheik, Sven Joscha and Reker, Jana and Riabov, Volodymyr}, issn = {1424-0637}, journal = {Annales Henri Poincare}, pages = {1991--2033}, publisher = {Springer Nature}, title = {{Prethermalization for deformed Wigner matrices}}, doi = {10.1007/s00023-024-01518-y}, volume = {26}, year = {2025}, } @inbook{18765, abstract = {Mosaic Analysis with Double Markers (MADM) represents a mouse genetic approach coupling differential fluorescent labeling to genetic manipulations in dividing cells and their lineages. MADM uniquely enables the generation and visualization of individual control or homozygous mutant cells in a heterozygous genetic environment. Among its diverse applications, MADM has been used to dissect cell-autonomous gene functions important for cortical development and neural development in general. The high cellular resolution offered by MADM also permits the analysis of transcriptomic changes of individual cells upon genetic manipulations. In this chapter, we describe an experimental protocol combining the generation and isolation of MADM-labeled cells with downstream single-cell RNA-sequencing technologies to probe cell-type specific phenotypes due to genetic mutations at single-cell resolution.}, author = {Cheung, Giselle T and Pauler, Florian and Hippenmeyer, Simon}, booktitle = {Lineage Tracing}, editor = {Garcia-Marques, Jorge and Lee, Tzumin}, isbn = {9781071643099}, issn = {1940-6029}, pages = {139--151}, publisher = {Springer Nature}, title = {{Probing Cell-Type Specificity of Mutant Phenotype at Transcriptomic Level Using Mosaic Analysis with Double Markers (MADM)}}, doi = {10.1007/978-1-0716-4310-5_7}, volume = {2886}, year = {2025}, } @article{18778, abstract = {Transcription by RNA polymerase II (Pol II) can be repressed by noncoding RNA, including the human RNA Alu. However, the mechanism by which endogenous RNAs repress transcription remains unclear. Here we present cryogenic-electron microscopy structures of Pol II bound to Alu RNA, which reveal that Alu RNA mimics how DNA and RNA bind to Pol II during transcription elongation. Further, we show how distinct domains of the general transcription factor TFIIF control repressive activity. Together, we reveal how a noncoding RNA can regulate mammalian gene expression.}, author = {Tluckova, Katarina and Kaczmarek, Beata M and Testa Salmazo, Anita P and Bernecky, Carrie A}, issn = {1545-9985}, journal = {Nature Structural & Molecular Biology}, pages = {607--612}, publisher = {Springer Nature}, title = {{Mechanism of mammalian transcriptional repression by noncoding RNA}}, doi = {10.1038/s41594-024-01448-7}, volume = {32}, year = {2025}, }