@article{18879,
  abstract     = {Our brain has remarkable computational power, generating sophisticated behaviors, storing memories over an individual’s lifetime, and producing higher cognitive functions. However, little of our neuroscience knowledge covers the human brain. Is this organ truly unique, or is it a scaled version of the extensively studied rodent brain? Combining multicellular patch-clamp recording with expansion-based superresolution microscopy and full-scale modeling, we determined the cellular and microcircuit properties of the human hippocampal CA3 region, a fundamental circuit for memory storage. In contrast to neocortical networks, human hippocampal CA3 displayed sparse connectivity, providing a circuit architecture that maximizes associational power. Human synapses showed unique reliability, high precision, and long integration times, exhibiting both species- and circuit-specific properties. Together with expanded neuronal numbers, these circuit characteristics greatly enhanced the memory storage capacity of CA3. Our results reveal distinct microcircuit properties of the human hippocampus and begin to unravel the inner workings of our most complex organ. },
  author       = {Watson, Jake and Vargas Barroso, Victor M and Morse, Rebecca and Navas Olivé, Andrea C and Tavakoli, Mojtaba and Danzl, Johann G and Tomschik, Matthias and Rössler, Karl and Jonas, Peter M},
  issn         = {1097-4172},
  journal      = {Cell},
  number       = {2},
  pages        = {501--514.e18},
  publisher    = {Elsevier},
  title        = {{Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory}},
  doi          = {10.1016/j.cell.2024.11.022},
  volume       = {188},
  year         = {2025},
}

@article{18880,
  abstract     = {In this paper, we provide a rate of convergence for a version of the Carathéodory convergence for the multiple SLE model with a Dyson Brownian motion driver towards its hydrodynamic limit, for β=1 and β=2. The results are obtained by combining techniques from the field of Schramm–Loewner Evolutions with modern techniques from random matrices. Our approach shows how one can apply modern tools used in the proof of universality in random matrix theory to the field of Schramm–Loewner Evolutions.},
  author       = {Campbell, Andrew J and Luh, Kyle and Margarint, Vlad},
  issn         = {2010-3271},
  journal      = {Random Matrices: Theory and Application},
  number       = {1},
  publisher    = {World Scientific Publishing},
  title        = {{Rate of convergence in multiple SLE using random matrix theory}},
  doi          = {10.1142/S201032632450028X},
  volume       = {14},
  year         = {2025},
}

@article{18881,
  abstract     = {The determination of the intrinsic properties of solid active material candidates is essential for their performance optimization. However, macroscopic electrodes and related analytical techniques show challenges concerning the number of additional influencing parameters. We explore recessed microelectrodes (rME) as a platform that allows for a binder-free investigation of Prussian Blue analogues (PBA), a family of promising battery materials. The enhanced diffusion using microelectrochemical tools is indispensable to assess the intrinsic material performance, overcoming the limitation of cation diffusion from the electrolyte to the solid interface during (dis)charging cycles and allowing the investigation of limiting steps in the coupled ion-electron transfer process. The intrinsic electrochemical performance of PBAs was studied in a three-electrode configuration by means of cyclic voltammetry and galvanostatic (dis)charging in aqueous Na+-containing electrolyte. We extended the evaluation to the role of the electrolyte on the performance of cathodic and anodic processes of a Mn-based PBA. Ex-situ and operando chemical characterization were coupled to support the microelectrochemical results.},
  author       = {Jiyane, Nomnotho and Santana Santos, Carla and Echevarria Poza, Igor and Palacios Corella, Mario and Abdillah Mahbub, Muhammad Adib and Marin-Tajadura, Gimena and Quast, Thomas and Ibáñez, Maria and Ventosa, Edgar and Schuhmann, Wolfgang},
  issn         = {2566-6223},
  journal      = {Batteries & Supercaps},
  number       = {3},
  publisher    = {Wiley},
  title        = {{Recessed microelectrodes as a platform to investigate the intrinsic redox process of Prussian blue analogs for energy storage application}},
  doi          = {10.1002/batt.202400743},
  volume       = {8},
  year         = {2025},
}

@article{18882,
  abstract     = {Ternary liquid-like thermoelectric materials have garnered significant attention due to their ultra-low lattice thermal conductivity. Among these, Ag8SnSe6 stands out for its exceptionally low sound velocity and thermal conductivity. However, the inherent poor electrical conductivity and suboptimal thermoelectric properties of Ag8SnSe6 necessitate further improvement. Here, a novel approach is initiated to enhance the thermoelectric properties of Ag8SnSe6 by combining low-dimensionalization with intrinsic doping. For the first time, this work successfully synthesizes single-phase Ag8SnSe6 nanocrystals, ≈10 nm in size, with the correct phase and composition using a robust and reliable colloidal method. This approach represents a significant improvement over previous reports on this material. Reducing the crystal domains of Ag8SnSe6 to the nanoscale induces quantum confinement effects, increasing the density of states near the Fermi surface. It also introduces additional grain boundaries, which lower the lattice thermal conductivity and simplify structural design. Moreover, incorporating small amounts of Sn nanopowder into the Ag8SnSe6 nanocrystals before consolidation further enhances the thermoelectric performance. Sn acts as a donor dopant, increasing the electronic concentration while at the same time improving their mobility by reducing interface barriers, thus significantly improving the material transport properties. Additionally, the presence of Sn leads to the formation of point defects, dislocations, and secondary phases, which increase phonon scattering and further reduce the thermal conductivity. Through this synergistic optimization, the figure of merit  shows a significant increase across a wide temperature range. Overall, a strategy is presented for the controlled preparation of Ag8SnSe6 nanocrystals, the decoupling of their electrical and thermal transport, and the practical application of this material to thermoelectric single-leg modules.},
  author       = {Zhao, Xueke and Li, Mengyao and Jia, Mochen and Fiedler, Christine and Nan, Bingfei and Yang, Dongwen and Li, Lei and Yuan, Zicheng and Song, Hongzhang and Liu, Yu and Ibáñez, Maria and Wang, Ziyu and Shan, Chongxin and Cabot, Andreu},
  issn         = {1616-3028},
  journal      = {Advanced Functional Materials},
  number       = {24},
  publisher    = {Wiley},
  title        = {{Low-dimensional structure modulation in Ag8SnSe6 for enhanced thermoelectric performance}},
  doi          = {10.1002/adfm.202421449},
  volume       = {35},
  year         = {2025},
}

@article{18892,
  abstract     = {Sick individuals often conceal their disease status to group members, thereby preventing social exclusion or aggression. Here we show by behavioural, chemical, immunological and infection load analyses that sick ant pupae instead actively emit a chemical signal that in itself is sufficient to trigger their own destruction by colony members. In our experiments, this altruistic disease-signalling was performed only by worker but not queen pupae. The lack of signalling by queen pupae did not constitute cheating behaviour, but reflected their superior immune capabilities. Worker pupae suffered from extensive pathogen replication whereas queen pupae were able to restrain their infection. Our data suggest the evolution of a finely-tuned signalling system in which it is not the induction of an individual’s immune response, but rather its failure to overcome the infection, that triggers pupal signalling for sacrifice. This demonstrates a balanced interplay between individual and social immunity that efficiently achieves whole-colony health.},
  author       = {Dawson, Erika and Hönigsberger, Michaela and Kampleitner, Niklas and Grasse, Anna V and Lindorfer, Lukas and Robb, Jennifer and Beikzadeh Abbasi, Farnaz and Strahodinsky, Florian and Leitner, Hanna and Rajendran, Harikrishnan and Schmitt, Thomas and Cremer, Sylvia},
  issn         = {2041-1723},
  journal      = {Nature Communications},
  publisher    = {Springer Nature},
  title        = {{Altruistic disease signalling in ant colonies}},
  doi          = {10.1038/s41467-025-66175-z},
  volume       = {16},
  year         = {2025},
}

@article{18984,
  abstract     = {Although planets have been found orbiting binary systems, whether they can survive binary interactions is debated. While the tightest-orbit binaries should host the most dynamically stable and long-lived circumbinary planetary systems, they are also the systems that are expected to experience mass transfer, common envelope evolution, or stellar mergers. In this study, we explore the effect of stable non-conservative mass transfer on the dynamical evolution of circumbinary planets. We present a new script that seamlessly integrates binary evolution data from the 1D binary stellar evolution code MESA into the N-body simulation code REBOUND. This integration framework enables a comprehensive examination of the dynamical evolution of circumbinary planets orbiting mass-transferring binaries, while simultaneously accounting for the detailed stellar structure evolution. In addition, we introduce a recalibration method to mitigate numerical errors from updates of binary properties during the system's dynamical evolution. We construct a reference binary model in which a 2.21M⊙ star loses its hydrogen-rich envelope through non-conservative mass transfer to the 1.76M⊙ companion star, creating a 0.38M⊙ subdwarf. We find the tightest stable orbital separation for circumbinary planets to be ≃2.5 times the binary separation after mass transfer. Accounting for tides by using the interior stellar structure, we find that tidal effects become apparent after the rapid mass transfer phase and start to fade away during the latter stage of the slow mass transfer phase. Our research provides a new framework for exploring circumbinary planet dynamics in interacting binary systems.},
  author       = {Xing, Zepei and Torres Rodriguez, Santiago and Götberg, Ylva Louise Linsdotter and Trani, Alessandro A. and Korol, Valeriya and Cuadra, Jorge},
  issn         = {1365-2966},
  journal      = {Monthly Notices of the Royal Astronomical Society},
  number       = {1},
  pages        = {285--292},
  publisher    = {Oxford University Press},
  title        = {{Combining REBOUND and MESA: Dynamical evolution of planets orbiting interacting binaries}},
  doi          = {10.1093/mnras/stae2820},
  volume       = {537},
  year         = {2025},
}

@article{18985,
  abstract     = {Persistent multiyear drought (MYD) events pose a growing threat to nature and humans in a changing climate. We identified and inventoried global MYDs by detecting spatiotemporally contiguous climatic anomalies, showing that MYDs have become drier, hotter, and led to increasingly diminished vegetation greenness. The global terrestrial land affected by MYDs has increased at a rate of 49,279 ± 14,771 square kilometers per year from 1980 to 2018. Temperate grasslands have exhibited the greatest declines in vegetation greenness during MYDs, whereas boreal and tropical forests have had comparably minor responses. With MYDs becoming more common, this global quantitative inventory of the occurrence, severity, trend, and impact of MYDs provides an important benchmark for facilitating more effective and collaborative preparedness toward mitigation of and adaptation to such extreme events.},
  author       = {Chen, Liangzhi and Brun, Philipp and Buri, Pascal and Fatichi, Simone and Gessler, Arthur and Mccarthy, Michael and Pellicciotti, Francesca and Stocker, Benjamin and Karger, Dirk Nikolaus},
  issn         = {1095-9203},
  journal      = {Science},
  number       = {6731},
  pages        = {278--284},
  publisher    = {AAAS},
  title        = {{Global increase in the occurrence and impact of multiyear droughts}},
  doi          = {10.1126/science.ado4245},
  volume       = {387},
  year         = {2025},
}

@article{18986,
  abstract     = {We consider a prototypical problem of Bayesian inference for a structured spiked model: a low-rank signal is corrupted by additive noise. While both information-theoretic and algorithmic limits are well understood when the noise is a Gaussian Wigner matrix, the more realistic case of structured noise still remains challenging. To capture the structure while maintaining mathematical tractability, a line of work has focused on rotationally invariant noise. However, existing studies either provide suboptimal algorithms or are limited to a special class of noise ensembles. In this paper, using tools from statistical physics (replica method) and random matrix theory (generalized spherical integrals) we establish the characterization of the information-theoretic limits for a noise matrix drawn from a general trace ensemble. Remarkably, our analysis unveils the asymptotic equivalence between the rotationally invariant model and a surrogate Gaussian one. Finally, we show how to saturate the predicted statistical limits using an efficient algorithm inspired by the theory of adaptive Thouless-Anderson-Palmer (TAP) equations.},
  author       = {Barbier, Jean and Camilli, Francesco and Xu, Yizhou and Mondelli, Marco},
  issn         = {2643-1564},
  journal      = {Physical Review Research},
  publisher    = {American Physical Society},
  title        = {{Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise}},
  doi          = {10.1103/PhysRevResearch.7.013081},
  volume       = {7},
  year         = {2025},
}

@article{18987,
  abstract     = {Biallelic variants in NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H))-ubiquinone oxidoreductase 1 alpha subcomplex 13 have been linked to mitochondrial complex I deficiency, nuclear type 28, based on three affected individuals from two families. With only two families reported, the clinical and molecular spectrum of NADH-ubiquinone oxidoreductase 1 alpha subcomplex 13–related diseases remains unclear. We report 10 additional affected individuals from nine independent families, identifying four missense variants (including recurrent c.170G > A) and three ultra-rare or novel predicted loss-of-function biallelic variants. Updated clinical–radiological data from previously reported families and a literature review compiling clinical features of all reported patients with isolated complex I deficiency caused by 43 genes encoding complex I subunits and assembly factors are also provided. Our cohort (mean age 7.8 ± 5.4 years; range 2.5–18) predominantly presented a moderate-to-severe neurodevelopmental syndrome with oculomotor abnormalities (84%), spasticity/hypertonia (83%), hypotonia (69%), cerebellar ataxia (66%), movement disorders (58%) and epilepsy (46%). Neuroimaging revealed bilateral symmetric T2 hyperintense substantia nigra lesions (91.6%) and optic nerve atrophy (66.6%). Protein modeling suggests missense variants destabilize a critical junction between the hydrophilic and membrane arms of complex I. Fibroblasts from two patients showed reduced complex I activity and compensatory complex IV activity increase. This study characterizes NADH-ubiquinone oxidoreductase 1 alpha subcomplex 13–related disease in 13 individuals, highlighting genotype–phenotype correlations.},
  author       = {Kaiyrzhanov, Rauan and Thompson, Kyle and Efthymiou, Stephanie and Mukushev, Askhat and Zharylkassyn, Akbota and Prasad, Chitra and Karimiani, Ehsan Ghayoor and Alvi, Javeria Raza and Niyazov, Dmitriy and Alahmad, Ahmad and Babaei, Meisam and Tajsharghi, Homa and Albash, Buthaina and Alaqeel, Ahmad and Charif, Majida and Hashemi, Narges and Heidari, Morteza and Kalantar, Seyed Mehdi and Lenaers, Guy and Mehrjardi, Mohammad Yahya Vahidi and Srinivasan, Varunvenkat M. and Gowda, Vykuntaraju K. and Mirabutalebi, Seyed Hamidreza and Carere, Deanna Alexis and Movahedinia, Mojtaba and Murphy, David and Mcfarland, Robert and Abdel-Hamid, Mohamed S. and Elhossini, Rasha M. and Alavi, Shahryar and Napier, Melanie and Belanger-Quintana, Amaya and Prasad, Asuri N. and Jakobczyk, Jessica and Roubertie, Agathe and Rupar, Tony and Sultan, Tipu and Toosi, Mehran Beiraghi and Sazanov, Leonid A and Severino, Mariasavina and Houlden, Henry and Taylor, Robert W. and Maroofian, Reza},
  issn         = {2632-1297},
  journal      = {Brain Communications},
  number       = {1},
  publisher    = {Oxford University Press},
  title        = {{Biallelic NDUFA13 variants lead to a neurodevelopmental phenotype with gradual neurological impairment}},
  doi          = {10.1093/braincomms/fcae453},
  volume       = {7},
  year         = {2025},
}

@misc{18991,
  abstract     = {Research data for the article "Learning reshapes the hippocampal representation hierarchy" from Chiossi et al. (PNAS, 2025). The data includes hippocampal CA1 unit activity and behaviour tracking of 5 Long Evans rats during the learning of an associative memory task. Detailed information can be found in the 'readme.txt' file.},
  author       = {Chiossi, Heloisa},
  keywords     = {hippocampus, electrophysiology, behavior},
  publisher    = {Institute of Science and Technology Austria},
  title        = {{Research data for the publication "Learning reshapes the hippocampal representation hierarchy"}},
  doi          = {10.15479/AT:ISTA:18991},
  year         = {2025},
}

@article{19002,
  abstract     = {A k-subcolouring of a graph G is a function f : V (G) → {0,...,k − 1} such that the set of
vertices coloured i induce a disjoint union of cliques. The subchromatic number, χsub(G),
is the minimum k such that G admits a k-subcolouring. Nešetril, ˇ Ossona de Mendez,
Pilipczuk, and Zhu (2020), recently raised the problem of finding tight upper bounds for
χsub(G2) when G is planar. We show that χsub(G2) ≤ 43 when G is planar, improving
their bound of 135. We give even better bounds when the planar graph G has larger girth.
Moreover, we show that χsub(G3) ≤ 95, improving the previous bound of 364. For these
we adapt some recent techniques of Almulhim and Kierstead (2022), while also extending
the decompositions of triangulated planar graphs of Van den Heuvel, Ossona de Mendez,
Quiroz, Rabinovich and Siebertz (2017), to planar graphs of arbitrary girth. Note that these
decompositions are the precursors of the graph product structure theorem of planar graphs.
We give improved bounds for χsub(Gp) for all p ≥ 2, whenever G has bounded treewidth,
bounded simple treewidth, bounded genus, or excludes a clique or biclique as a minor.
For this we introduce a family of parameters which form a gradation between the strong
and the weak colouring numbers. We give upper bounds for these parameters for graphs
coming from such classes.
Finally, we give a 2-approximation algorithm for the subchromatic number of graphs
having a layering in which each layer has bounded cliquewidth and this layering is
computable in polynomial time (like the class of all dth powers of planar graphs, for fixed
d). This algorithm works even if the power p and the graph G is unknown.},
  author       = {Cortés, Pedro P. and Kumar, Pankaj and Moore, Benjamin and Ossona de Mendez, Patrice and Quiroz, Daniel A.},
  issn         = {0012-365X},
  journal      = {Discrete Mathematics},
  number       = {4},
  publisher    = {Elsevier},
  title        = {{Subchromatic numbers of powers of graphs with excluded minors}},
  doi          = {10.1016/j.disc.2024.114377},
  volume       = {348},
  year         = {2025},
}

@article{19012,
  abstract     = {False vacuum decay—the transition from a metastable quantum state to a true vacuum state—plays an important role in quantum field theory and non-equilibrium phenomena such as phase transitions and dynamical metastability. The non-perturbative nature of false vacuum decay and the limited experimental access to this process make it challenging to study, leaving several open questions regarding how true vacuum bubbles form, move and interact. Here we observe quantized bubble formation in real time, a key feature of false vacuum decay dynamics, using a quantum annealer with 5,564 superconducting flux qubits. We develop an effective model that captures both initial bubble creation and subsequent interactions, and remains accurate under dissipation. The annealer reveals coherent scaling laws in the driven many-body dynamics for more than 1,000 intrinsic qubit time units. This work provides a method for investigating false vacuum dynamics of large quantum systems in quantum annealers.},
  author       = {Vodeb, Jaka and Desaules, Jean-Yves Marc and Hallam, Andrew and Rava, Andrea and Humar, Gregor and Willsch, Dennis and Jin, Fengping and Willsch, Madita and Michielsen, Kristel and Papić, Zlatko},
  issn         = {1745-2481},
  journal      = {Nature Physics},
  pages        = {386--392},
  publisher    = {Springer Nature},
  title        = {{Stirring the false vacuum via interacting quantized bubbles on a 5,564-qubit quantum annealer}},
  doi          = {10.1038/s41567-024-02765-w},
  volume       = {21},
  year         = {2025},
}

@article{19015,
  abstract     = {When microplastics (MPs) enter water bodies, they undergo various transport processes, including sedimentation, which can be influenced by factors such as particle size, density, and interactions with other particles. Surface waters contain suspended natural particles (e.g., clay and silt), which may impact MP settling rates. Here, we investigated how the presence of suspended sediments (SS) influenced the deposition patterns and rates of MPs in turbid waters. We systematically analyzed the settling velocities of particles, including different MP sizes and SS concentrations, in a plexiglass column with a camera array. For each experimental variant, we collected data on thousands of individual MPs, strengthening the statistical analysis of the particles’ velocities. Simultaneous measurements of the SS flow and MPs trajectories revealed that the SS induced complex flow patterns, with MPs spending more time in downwelling flow regions, thereby accelerating MPs sedimentation. This effect was more pronounced when SS were aggregated. Additionally, we found that smaller MP fragments were more affected by the fluctuations than spheres or larger fragments. Collectively, our results provide valuable data for future MP fate models and help to understand the sedimentation processes of MPs in natural waters, which is crucial for assessing their environmental transport and impact.},
  author       = {Parrella, Francesco and Brizzolara, Stefano and Holzner, Markus and Mitrano, Denise M.},
  issn         = {1520-5851},
  journal      = {Environmental Science and Technology},
  number       = {4},
  pages        = {2257--2265},
  publisher    = {American Chemical Society},
  title        = {{Microplastics settling in turbid water: Impacts of sediments-induced flow patterns on particle deposition rates}},
  doi          = {10.1021/acs.est.4c10551},
  volume       = {59},
  year         = {2025},
}

@article{19017,
  abstract     = {Let f(r)(n;s,k) denote the maximum number of edges in an n-vertex r-uniform hypergraph containing no subgraph with k edges and at most s vertices. Brown, Erdős and Sós [New directions in the theory of graphs (Proc. Third Ann Arbor Conf., Univ. Michigan 1971), pp. 53--63, Academic Press 1973] conjectured that the limit limn→∞n−2f(3)(n;k+2,k) exists for all k. The value of the limit was previously determined for k=2 in the original paper of Brown, Erdős and Sós, for k=3 by Glock [Bull. Lond. Math. Soc. 51 (2019) 230--236] and for k=4 by Glock, Joos, Kim, Kühn, Lichev and Pikhurko [arXiv:2209.14177, accepted by Proc. Amer. Math. Soc.] while Delcourt and Postle [arXiv:2210.01105, accepted by Proc. Amer. Math. Soc.] proved the conjecture (without determining the limiting value).
In this paper, we determine the value of the limit in the Brown-Erdős-Sós Problem for k∈{5,6,7}. More generally, we obtain the value of limn→∞n−2f(r)(n;rk−2k+2,k) for all r≥3 and k∈{5,6,7}. In addition, by combining these new values with recent results of Bennett, Cushman and Dudek [arXiv:2309.00182] we obtain new asymptotic values for several generalised Ramsey numbers.},
  author       = {Glock, Stefan and Kim, Jaehoon and Lichev, Lyuben and Pikhurko, Oleg and Sun, Shumin},
  issn         = {1496-4279},
  journal      = {Canadian Journal of Mathematics},
  pages        = {1--43},
  publisher    = {Cambridge University Press},
  title        = {{On the (k + 2, k)-problem of Brown, Erdős, and Sós for k = 5,6,7}},
  doi          = {10.4153/s0008414x25000021},
  year         = {2025},
}

@article{19018,
  abstract     = {The online semi-random graph process is a one-player game which starts with the empty graph on n vertices. At every round, a player (called Builder) is presented with a vertex v chosen uniformly at random and independently from previous rounds, and constructs an edge of their choice that is incident to v. Inspired by recent advances on the semi-random graph process, we define a family of generalized online semi-random models.
We analyse a particular instance that shares similar features with the original semi-random graph process and determine the hitting times of the classical graph properties minimum degree k,k-connectivity, containment of a perfect matching, a Hamiltonian cycle and an 
H-factor for a fixed graph H possessing an additional tree-like property. Along the way, we derive a few consequences of the famous Aldous-Broder algorithm that may be of independent interest.},
  author       = {Burova, Sofiya and Lichev, Lyuben},
  issn         = {0195-6698},
  journal      = {European Journal of Combinatorics},
  publisher    = {Elsevier},
  title        = {{The semi-random tree process}},
  doi          = {10.1016/j.ejc.2025.104120},
  volume       = {126},
  year         = {2025},
}

@article{19023,
  abstract     = {Alcohol consumption is an important risk factor for multiple diseases. It is typically assessed via self-report, which is open to measurement error through recall bias. Instead, molecular data such as blood-based DNA methylation (DNAm) could be used to derive a more objective measure of alcohol consumption by incorporating information from cytosine-phosphate-guanine (CpG) sites known to be linked to the trait. Here, we explore the epigenetic architecture of self-reported weekly units of alcohol consumption in the Generation Scotland study. We first create a blood-based epigenetic score (EpiScore) of alcohol consumption using elastic net penalized linear regression. We explore the effect of pre-filtering for CpG features ahead of elastic net, as well as differential patterns by sex and by units consumed in the last week relative to an average week. The final EpiScore was trained on 16,717 individuals and tested in four external cohorts: the Lothian Birth Cohorts (LBC) of 1921 and 1936, the Sister Study, and the Avon Longitudinal Study of Parents and Children (total N across studies > 10,000). The maximum Pearson correlation between the EpiScore and self-reported alcohol consumption within cohort ranged from 0.41 to 0.53. In LBC1936, higher EpiScore levels had significant associations with poorer global brain imaging metrics, whereas self-reported alcohol consumption did not. Finally, we identified two novel CpG loci via a Bayesian penalized regression epigenome-wide association study of alcohol consumption. Together, these findings show how DNAm can objectively characterize patterns of alcohol consumption that associate with brain health, unlike self-reported estimates.},
  author       = {Bernabeu, Elena and Chybowska, Aleksandra D. and Kresovich, Jacob K. and Suderman, Matthew and Mccartney, Daniel L. and Hillary, Robert F. and Corley, Janie and Valdés-Hernández, Maria Del C. and Maniega, Susana Muñoz and Bastin, Mark E. and Wardlaw, Joanna M. and Xu, Zongli and Sandler, Dale P. and Campbell, Archie and Harris, Sarah E. and Mcintosh, Andrew M. and Taylor, Jack A. and Yousefi, Paul and Cox, Simon R. and Evans, Kathryn L. and Robinson, Matthew Richard and Vallejos, Catalina A. and Marioni, Riccardo E.},
  issn         = {1868-7083},
  journal      = {Clinical Epigenetics},
  publisher    = {Springer Nature},
  title        = {{Blood-based epigenome-wide association study and prediction of alcohol consumption}},
  doi          = {10.1186/s13148-025-01818-y},
  volume       = {17},
  year         = {2025},
}

@article{19024,
  abstract     = {Aqueous two-phase systems (ATPSs), phase-separating solutions of water soluble but mutually immiscible molecular species, offer fascinating prospects for selective partitioning, purification, and extraction. Here, we formulate a general Brownian dynamics based coarse-grained simulation model for an ATPS of two water soluble but mutually immiscible polymer species. Including additional solute species into the model is straightforward, which enables capturing the assembly and partitioning response of, e.g., nanoparticles (NPs), additional macromolecular species, or impurities in the ATPS. We demonstrate that the simulation model captures satisfactorily the phase separation, partitioning, and interfacial properties of an actual ATPS using a model ATPS in which a polymer mixture of dextran and polyethylene glycol (PEG) phase separates, and magnetic NPs selectively partition into one of the two polymeric phases. Phase separation and NP partitioning are characterized both via the computational model and experimentally, under different conditions. The simulation model captures the trends observed in the experimental system and quantitatively links the partitioning behavior to the component species interactions. Finally, the simulation model reveals that the ATPS interface fluctuations in systems with magnetic NPs as a partitioned species can be controlled by the magnetic field at length scales much smaller than those probed experimentally to date.},
  author       = {Scacchi, Alberto and Rigoni, Carlo and Haataja, Mikko and Timonen, Jaakko V.I. and Sammalkorpi, Maria},
  issn         = {1095-7103},
  journal      = {Journal of Colloid and Interface Science},
  pages        = {1135--1146},
  publisher    = {Elsevier},
  title        = {{A coarse-grained model for aqueous two-phase systems: Application to ferrofluids}},
  doi          = {10.1016/j.jcis.2025.01.256},
  volume       = {686},
  year         = {2025},
}

@article{19026,
  abstract     = {The back-action damping of mechanical motion by electromagnetic radiation is typically overwhelmed by internal loss channels unless demanding experimental ingredients such as superconducting resonators, high-quality optical cavities, or large magnetic fields are employed. Here we demonstrate the first room temperature, cavity-free, all-electric device where back-action damping exceeds internal loss, enabled by a mechanically compliant parallel-plate capacitor with a nanoscale plate separation and an aspect ratio exceeding 1,000. The device has 4 orders of magnitude lower insertion loss than a comparable commercial quartz crystal and achieves a position imprecision rivaling optical interferometers. With the help of a back-action isolation scheme, we observe radiative cooling of mechanical motion by a remote cryogenic load. This work provides a technologically accessible route to high-precision sensing, transduction, and signal processing.},
  author       = {Puglia, Denise and Odessey, Rachel H and Burns, Peter and Luhmann, Niklas and Schmid, Silvan and Higginbotham, Andrew P},
  issn         = {1530-6992},
  journal      = {Nano Letters},
  number       = {7},
  pages        = {2749--2755},
  publisher    = {American Chemical Society},
  title        = {{Room temperature, cavity-free capacitive strong coupling to mechanical motion}},
  doi          = {10.1021/acs.nanolett.4c05796},
  volume       = {25},
  year         = {2025},
}

@article{19027,
  abstract     = {Stochastic PDEs of fluctuating hydrodynamics are a powerful tool for the description of fluctuations in many-particle systems. In this paper, we develop and analyze a multilevel Monte Carlo (MLMC) scheme for the Dean–Kawasaki equation, a pivotal representative of this class of SPDEs. We prove analytically and demonstrate numerically that our MLMC scheme provides a significant reduction in computational cost (with respect to a standard Monte Carlo method) in the simulation of the Dean–Kawasaki equation. Specifically, we link this reduction in cost to having a sufficiently large average particle density and show that sizeable cost reductions can be obtained even when we have solutions with regions of low density. Numerical simulations are provided in the two-dimensional case, confirming our theoretical predictions. Our results are formulated entirely in terms of the law of distributions rather than in terms of strong spatial norms: this crucially allows for MLMC speed-ups altogether despite the Dean–Kawasaki equation being highly singular.},
  author       = {Cornalba, Federico and Fischer, Julian L},
  issn         = {1095-7170},
  journal      = {SIAM Journal on Numerical Analysis},
  number       = {1},
  pages        = {262--287},
  publisher    = {Society for Industrial and Applied Mathematics},
  title        = {{Multilevel Monte Carlo methods for the Dean–Kawasaki equation from fluctuating hydrodynamics}},
  doi          = {10.1137/23M1617345},
  volume       = {63},
  year         = {2025},
}

@misc{19033,
  abstract     = {This data set contains the simulation input files, scripts, and figures data belonging to the publication

Alberto Scacchi, Carlo Rigoni, Mikko P. Haataja, Jakko V. I. Timonen, and Maria Sammalkorpi, "A Coarse-grained Model for Aqueous Two-phase Systems: Application to Ferrofluids", Journal of Colloids and Interface Science (2025). https://doi.org/10.1016/j.jcis.2025.01.256.},
  author       = {Scacchi, Alberto},
  publisher    = {Fairdata},
  title        = {{2025_SCACCHI_JCIS}},
  doi          = {10.23729/4fb80194-cdb2-4f49-94f4-f8a87b8e29c1},
  year         = {2025},
}