@article{11105,
  abstract     = {Nuclear-pore complexes (NPCs) are large protein channels that span the nuclear envelope (NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of the typically 2,000–4,000 pores in the NE of vertebrate cells is composed of multiple copies of 30 different proteins known as nucleoporins. The evolutionarily conserved NPC proteins have the well-characterized function of mediating the transport of molecules between the nucleoplasm and the cytoplasm. Mutations in nucleoporins are often linked to specific developmental defects and disease, and the resulting phenotypes are usually interpreted as the consequences of perturbed nuclear transport activity. However, recent evidence suggests that NPCs have additional functions in chromatin organization and gene regulation, some of which might be independent of nuclear transport. Here, we review the transport-dependent and transport-independent roles of NPCs in the regulation of nuclear function and gene expression.},
  author       = {Capelson, Maya and HETZER, Martin W},
  issn         = {1469-3178},
  journal      = {EMBO reports},
  keywords     = {Genetics, Molecular Biology, Biochemistry},
  number       = {7},
  pages        = {697--705},
  publisher    = {EMBO},
  title        = {{The role of nuclear pores in gene regulation, development and disease}},
  doi          = {10.1038/embor.2009.147},
  volume       = {10},
  year         = {2009},
}

@article{11106,
  abstract     = {Formation of the nuclear envelope (NE) around segregated chromosomes occurs by the reshaping of the endoplasmic reticulum (ER), a reservoir for disassembled nuclear membrane components during mitosis. In this study, we show that inner nuclear membrane proteins such as lamin B receptor (LBR), MAN1, Lap2β, and the trans-membrane nucleoporins Ndc1 and POM121 drive the spreading of ER membranes into the emerging NE via their capacity to bind chromatin in a collaborative manner. Despite their redundant functions, decreasing the levels of any of these trans-membrane proteins by RNAi-mediated knockdown delayed NE formation, whereas increasing the levels of any of them had the opposite effect. Furthermore, acceleration of NE formation interferes with chromosome separation during mitosis, indicating that the time frame over which chromatin becomes membrane enclosed is physiologically relevant and regulated. These data suggest that functionally distinct classes of chromatin-interacting membrane proteins, which are present at nonsaturating levels, collaborate to rapidly reestablish the nuclear compartment at the end of mitosis.},
  author       = {Anderson, Daniel J. and Vargas, Jesse D. and Hsiao, Joshua P. and HETZER, Martin W},
  issn         = {1540-8140},
  journal      = {Journal of Cell Biology},
  keywords     = {Cell Biology},
  number       = {2},
  pages        = {183--191},
  publisher    = {Rockefeller University Press},
  title        = {{Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo}},
  doi          = {10.1083/jcb.200901106},
  volume       = {186},
  year         = {2009},
}

@article{11107,
  abstract     = {Nucleocytoplasmic transport occurs exclusively through nuclear pore complexes (NPCs) embedded in pores formed by inner and outer nuclear membrane fusion. The mechanism for de novo pore and NPC biogenesis remains unclear. Reticulons (RTNs) and Yop1/DP1 are conserved membrane protein families required to form and maintain the tubular endoplasmic reticulum (ER) and the postmitotic nuclear envelope. In this study, we report that members of the RTN and Yop1/DP1 families are required for nuclear pore formation. Analysis of Saccharomyces cerevisiae prp20-G282S and nup133Δ NPC assembly mutants revealed perturbations in Rtn1–green fluorescent protein (GFP) and Yop1-GFP ER distribution and colocalization to NPC clusters. Combined deletion of RTN1 and YOP1 resulted in NPC clustering, nuclear import defects, and synthetic lethality with the additional absence of Pom34, Pom152, and Nup84 subcomplex members. We tested for a direct role in NPC biogenesis using Xenopus laevis in vitro assays and found that anti-Rtn4a antibodies specifically inhibited de novo nuclear pore formation. We hypothesize that these ER membrane–bending proteins mediate early NPC assembly steps.},
  author       = {Dawson, T. Renee and Lazarus, Michelle D. and HETZER, Martin W and Wente, Susan R.},
  issn         = {1540-8140},
  journal      = {Journal of Cell Biology},
  keywords     = {Cell Biology},
  number       = {5},
  pages        = {659--675},
  publisher    = {Rockefeller University Press},
  title        = {{ER membrane–bending proteins are necessary for de novo nuclear pore formation}},
  doi          = {10.1083/jcb.200806174},
  volume       = {184},
  year         = {2009},
}

@article{11108,
  abstract     = {In dividing cells, nuclear pore complexes (NPCs) disassemble during mitosis and reassemble into the newly forming nuclei. However, the fate of nuclear pores in postmitotic cells is unknown. Here, we show that NPCs, unlike other nuclear structures, do not turn over in differentiated cells. While a subset of NPC components, like Nup153 and Nup50, are continuously exchanged, scaffold nucleoporins, like the Nup107/160 complex, are extremely long-lived and remain incorporated in the nuclear membrane during the entire cellular life span. Besides the lack of nucleoporin expression and NPC turnover, we discovered an age-related deterioration of NPCs, leading to an increase in nuclear permeability and the leaking of cytoplasmic proteins into the nucleus. Our finding that nuclear “leakiness” is dramatically accelerated during aging and that a subset of nucleoporins is oxidatively damaged in old cells suggests that the accumulation of damage at the NPC might be a crucial aging event.},
  author       = {D'Angelo, Maximiliano A. and Raices, Marcela and Panowski, Siler H. and HETZER, Martin W},
  issn         = {0092-8674},
  journal      = {Cell},
  keywords     = {General Biochemistry, Genetics and Molecular Biology},
  number       = {2},
  pages        = {284--295},
  publisher    = {Elsevier},
  title        = {{Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells}},
  doi          = {10.1016/j.cell.2008.11.037},
  volume       = {136},
  year         = {2009},
}

@article{1038,
  abstract     = {One possible way to produce ultra-cold, high-phase-space-density quantum gases of molecules in the rovibronic ground state is given by molecule association from quantum-degenerate atomic gases on a Feshbach resonance and subsequent coherent optical multi-photon transfer into the rovibronic ground state. In ultra-cold samples of Cs2 molecules, we observe two-photon dark resonances that connect the intermediate rovibrational level |v=73,J=2 with the rovibrational ground state |v=0,J=0 of the singlet X 1 ∑ g + ground-state potential. For precise dark resonance spectroscopy we exploit the fact that it is possible to efficiently populate the level |v=73,J=2 by two-photon transfer from the dissociation threshold with the stimulated Raman adiabatic passage (STIRAP) technique. We find that at least one of the two-photon resonances is sufficiently strong to allow future implementation of coherent STIRAP transfer of a molecular quantum gas to the rovibrational ground state |v=0,J=0.},
  author       = {Mark, Manfred and Danzl, Johann G and Haller, Elmar and Gustavsson, Mattias and Bouloufa, Nadia and Dulieu, Olivier and Salami, Houssam and Bergeman, Thomas and Ritsch, Helmut and Hart, Russell and Nägerl, Hanns},
  journal      = {Applied Physics B: Lasers and Optics},
  number       = {2},
  pages        = {219 -- 225},
  publisher    = {Springer},
  title        = {{Dark resonances for ground-state transfer of molecular quantum gases}},
  doi          = {10.1007/s00340-009-3407-1},
  volume       = {95},
  year         = {2009},
}

@article{1040,
  abstract     = {Ultracold atomic physics offers myriad possibilities to study strongly correlated many-body systems in lower dimensions. Typically, only ground-state phases are accessible. Using a tunable quantum gas of bosonic cesium atoms, we realized and controlled in one-dimensional geometry a highly excited quantum phase that is stabilized in the presence of attractive interactions by maintaining and strengthening quantum correlations across a confinement-induced resonance. We diagnosed the crossover from repulsive to attractive interactions in terms of the stiffness and energy of the system. Our results open up the experimental study of metastable, excited, many-body phases with strong correlations and their dynamical properties.},
  author       = {Haller, Elmar and Gustavsson, Mattias and Mark, Manfred and Danzl, Johann G and Hart, Russell and Pupillo, Guido and Nägerl, Hanns},
  journal      = {Science},
  number       = {5945},
  pages        = {1224 -- 1227},
  publisher    = {American Association for the Advancement of Science},
  title        = {{Realization of an excited, strongly correlated quantum gas Phase}},
  doi          = {10.1126/science.1175850},
  volume       = {325},
  year         = {2009},
}

@article{1041,
  abstract     = {We demonstrate efficient transfer of ultracold molecules into a deeply bound rovibrational level of the singlet ground state potential in the presence of an optical lattice. The overall molecule creation efficiency is 25%, and the transfer efficiency to the rovibrational level |v = 73, J = 2) is above 80%. We find that the molecules in |v = 73, J = 2) are trapped in the optical lattice, and that the lifetime in the lattice is limited by optical excitation by the lattice light. The molecule trapping time for a lattice depth of 15 atomic recoil energies is about 20 ms. We determine the trapping frequency by the lattice phase and amplitude modulation technique. It will now be possible to transfer the molecules to the rovibrational ground state |v = 0, J = 0) in the presence of the optical lattice.},
  author       = {Danzl, Johann G and Mark, Manfred and Haller, Elmar and Gustavsson, Mattias and Hart, Russell and Liem, Andreas and Zellmer, Holger and Nägerl, Hanns},
  journal      = {New Journal of Physics},
  publisher    = {IOP Publishing Ltd.},
  title        = {{Deeply bound ultracold molecules in an optical lattice}},
  doi          = {10.1088/1367-2630/11/5/055036},
  volume       = {11},
  year         = {2009},
}

@article{1043,
  abstract     = {One possibility for the creation of ultracold, high phase space density quantum gases of molecules in the rovibronic ground state relies on first associating weakly-bound molecules from quantum-degenerate atomic gases on a Feshbach resonance and then transferring the molecules via several steps of coherent two-photon stimulated Raman adiabatic passage (STIRAP) into the rovibronic ground state. Here, in ultracold samples of Cs2 Feshbach molecules produced out of ultracold samples of Cs atoms, we observe several optical transitions to deeply-bound rovibrational levels of the excited 0 u+ molecular potentials with high resolution. At least one of these transitions, although rather weak, allows efficient STIRAP transfer into the deeply-bound vibrational level v = 73> of the singlet X 1Σg+ ground state potential, as recently demonstrated (J. G. Danzl, E. Haller, M. Gustavsson, M. J. Mark, R. Hart, N. Bouloufa, O. Dulieu, H. Ritsch, and H.-C. Nägerl, Science, 2008, 321, 1062). From this level, the rovibrational ground state v = 0, J = 0> can be reached with one more transfer step. In total, our results show that coherent ground state transfer for Cs2 is possible using a maximum of two successive two-photon STIRAP processes or one single four-photon STIRAP process.},
  author       = {Danzl, Johann G and Mark, Manfred and Haller, Elmar and Gustavsson, Mattias and Bouloufa, Nadia and Dulieu, Olivier and Ritsch, Helmut and Hart, Russell and Nägerl, Hanns},
  journal      = {Faraday Discussions},
  pages        = {283 -- 295},
  publisher    = {Royal Society of Chemistry},
  title        = {{Precision molecular spectroscopy for ground state transfer of molecular quantum gases}},
  doi          = {10.1039/b820542f},
  volume       = {142},
  year         = {2009},
}

@inproceedings{2094,
  abstract     = {This paper introduces a data-driven representation and modeling technique for simulating non-linear heterogeneous soft tissue. It simplifies the construction of convincing deformable models by avoiding complex selection and tuning of physical material parameters, yet retaining the richness of non-linear heterogeneous behavior. We acquire a set of example deformations of a real object, and represent each of them as a spatially varying stress-strain relationship in a finite-element model. We then model the material by non-linear interpolation of these stress-strain relationships in strain-space. Our method relies on a simple-to-build capture system and an efficient run-time simulation algorithm based on incremental loading, making it suitable for interactive computer graphics applications. We present the results of our approach for several non-linear materials and biological soft tissue, with accurate agreement of our model to the measured data. },
  author       = {Bernd Bickel and Bac̈her, Moritz and Otaduy, Miguel A and Matusik, Wojciech and Pfister, Hanspeter and Groß, Markus S},
  number       = {3},
  publisher    = {ACM},
  title        = {{Capture and modeling of non-linear heterogeneous soft tissue}},
  doi          = {10.1145/1576246.1531395 },
  volume       = {28},
  year         = {2009},
}

@article{21150,
  abstract     = {The crystal structure of d(CACACG)·d(CGTGTG) was solved to a resolution of 2.05 Å in space group P21. The duplex assumes the left-handed Z-DNA structure. The presence of two A·T base pairs in the hexamer does not greatly affect the conformation. The most significant changes compared with the regular structure of Z-DNA are in the values of twist in the central portion of the helix. This variation, as well as others in the values of roll, inclination etc., follow the pattern observed previously in the structure of d(CGCACG)·d(CGTGCG).},
  author       = {Venkadesh, S. and Mandal, Pradeep K and Gautham, N.},
  issn         = {1744-3091},
  journal      = {Acta Crystallographica Section F Structural Biology Communications},
  number       = {1},
  pages        = {8--13},
  publisher    = {International Union of Crystallography},
  title        = {{The structure of d(CACACG)·d(CGTGTG)}},
  doi          = {10.1107/s1744309108037706},
  volume       = {65},
  year         = {2009},
}

@article{2119,
  abstract     = {Let (E, H, μ) be an abstract Wiener space and let DV : = V D, where D denotes the Malliavin derivative and V is a closed and densely defined operator from H into another Hilbert space under(H, {combining low line}). Given a bounded operator B on under(H, {combining low line}), coercive on the range over(R (V), -), we consider the operators A : = V* B V in H and under(A, {combining low line}) : = V V* B in under(H, {combining low line}), as well as the realisations of the operators L : = DV* B DV and under(L, {combining low line}) : = DV DV* B in Lp (E, μ) and Lp (E, μ ; under(H, {combining low line})) respectively, where 1 < p < ∞. Our main result asserts that the following four assertions are equivalent: (1)D (sqrt(L)) = D (DV) with {norm of matrix} sqrt(L) f {norm of matrix}p {minus tilde} {norm of matrix} DV f {norm of matrix}p for f ∈ D (sqrt(L));(2)under(L, {combining low line}) admits a bounded H∞-functional calculus on over(R (DV), -);(3)D (sqrt(A)) = D (V) with {norm of matrix} sqrt(A) h {norm of matrix} {minus tilde} {norm of matrix} V h {norm of matrix} for h ∈ D (sqrt(A));(4)under(A, {combining low line}) admits a bounded H∞-functional calculus on over(R (V), -). Moreover, if these conditions are satisfied, then D (L) = D (DV2) ∩ D (DA). The equivalence (1)-(4) is a non-symmetric generalisation of the classical Meyer inequalities of Malliavin calculus (where under(H, {combining low line}) = H, V = I, B = frac(1, 2) I). A one-sided version of (1)-(4), giving Lp-boundedness of the Riesz transform DV / sqrt(L) in terms of a square function estimate, is also obtained. As an application let -A generate an analytic C0-contraction semigroup on a Hilbert space H and let -L be the Lp-realisation of the generator of its second quantisation. Our results imply that two-sided bounds for the Riesz transform of L are equivalent with the Kato square root property for A. The boundedness of the Riesz transform is used to obtain an Lp-domain characterisation for the operator L.},
  author       = {Jan Maas and van Neerven, Jan M},
  journal      = {Journal of Functional Analysis},
  number       = {8},
  pages        = {2410 -- 2475},
  publisher    = {Academic Press},
  title        = {{Boundedness of Riesz transforms for elliptic operators on abstract Wiener spaces}},
  doi          = {10.1016/j.jfa.2009.07.001},
  volume       = {257},
  year         = {2009},
}

@inproceedings{2136,
  abstract     = {The local atomic structure of PbTiO3, BaTiO3, and KNbO3 perovskite-type crystals and K x Na1 − x NbO3 solid solutions in different phases is investigated using the angular dependence of the pre-edge structure of the Ti and Nb K X-ray absorption spectra and the EXAFS data. In noncubic phases, a considerable deviation of the local structure from the structure determined from diffraction data is observed only for the tetragonal phase of the BaTiO3 crystal. It is revealed that, in the cubic phase of niobates, the niobium atoms are characterized by significant displacements from the centrosymmetric positions along the threefold axes, so that they are close in the magnitude and the direction to the displacements in the low-temperatures rhombohedral phases.},
  author       = {Vedrinskiǐ, Rostislav V and Kraǐzman, V. L and Mikhail Lemeshko and Nazarenko, Elena S and Novakovich, Alexander A and Reznichenko, Larisa A and Fokin, Vladimir N and Shuvaeva, Victoria A},
  number       = {7},
  pages        = {1394 -- 1398},
  publisher    = {Springer},
  title        = {{Local atomic structure of niobates and titanates from X-ray absorption spectroscopic data}},
  doi          = {10.1134/S106378340907018X},
  volume       = {51},
  year         = {2009},
}

@article{2137,
  abstract     = {Relying on the quantization rule of Raab and Friedrich [Phys. Rev. A (2009) in press], we derive simple and accurate formulae for the number of rotational states supported by a weakly bound vibrational level of a diatomic molecular ion. We also provide analytic estimates of the rotational constants of any such levels up to threshold for dissociation and obtain a criterion for determining whether a given weakly bound vibrational level is rotationless. The results depend solely on the long-range part of the molecular potential.},
  author       = {Mikhail Lemeshko and Frierich, Bretislav},
  journal      = {Journal of Atomic and Molecular Sciences},
  number       = {1},
  pages        = {41 -- 47},
  publisher    = {Global Science Press},
  title        = {{Rotational structure of weakly bound molecular ions}},
  doi          = {10.4208/jams.101009.110209a},
  volume       = {1},
  year         = {2009},
}

@article{2149,
  abstract     = {We investigate the effects of a magnetic field on the dynamics of rotationally inelastic collisions of open-shell molecules (Σ2, Σ3, and Π2) with closed-shell atoms. Our treatment makes use of the Fraunhofer model of matter wave scattering and its recent extension to collisions in electric [M. Lemeshko and B. Friedrich, J. Chem. Phys. 129, 024301 (2008)] and radiative fields [M. Lemeshko and B. Friedrich, Int. J. Mass. Spec. 280, 19 (2009)]. A magnetic field aligns the molecule in the space-fixed frame and thereby alters the effective shape of the diffraction target. This significantly affects the differential and integral scattering cross sections. We exemplify our treatment by evaluating the magnetic-field-dependent scattering characteristics of the He-CaH (XΣ+2), He-O2 (XΣ–3), and He-OH (XΠΩ2) systems at thermal collision energies. Since the cross sections can be obtained for different orientations of the magnetic field with respect to the relative velocity vector, the model also offers predictions about the frontal-versus-lateral steric asymmetry of the collisions. The steric asymmetry is found to be almost negligible for the He-OH system, weak for the He-CaH collisions, and strong for the He-O2. While odd ΔM transitions dominate the He-OH [J=3/2,f→J′,e/f] integral cross sections in a magnetic field parallel to the relative velocity vector, even ΔM transitions prevail in the case of the He-CaH (X2Σ+) and He-O2 (XΣ−3) collision systems. For the latter system, the magnetic field opens inelastic channels that are closed in the absence of the field. These involve the transitions N=1,J=0→N′, J′ with J′=N′.},
  author       = {Mikhail Lemeshko and Friedrich, Břetislav},
  journal      = {Physical Review A - Atomic, Molecular, and Optical Physics},
  number       = {1},
  publisher    = {American Physical Society},
  title        = {{Collisions of paramagnetic molecules in magnetic fields: An analytic model based on Fraunhofer diffraction of matter waves}},
  doi          = {10.1103/PhysRevA.79.012718},
  volume       = {79},
  year         = {2009},
}

@article{2150,
  abstract     = {We examine the effects of a linearly polarized nonresonant radiative field on the dynamics of rotationally inelastic Na+ + N2 collisions at eV collision energies. Our treatment is based on the Fraunhofer model of matter wave scattering and its recent extension to collisions in electric fields [M. Lemeshko, B. Friedrich, J. Chem. Phys. 129 (2008) 024301]. The nonresonant radiative field changes the effective shape of the target molecule by aligning it in the space-fixed frame. This markedly alters the differential and integral scattering cross-sections. As the cross-sections can be evaluated for a polarization of the radiative field collinear or perpendicular to the relative velocity vector, the model also offers predictions about steric asymmetry of the collisions.},
  author       = {Mikhail Lemeshko and Friedrich, Břetislav},
  journal      = {International Journal of Mass Spectrometry},
  number       = {1-3},
  pages        = {19 -- 25},
  publisher    = {Elsevier},
  title        = {{The effect of a nonresonant radiative field on low-energy rotationally inelastic Na+ + N2 collisions}},
  doi          = {10.1016/j.ijms.2008.06.010 },
  volume       = {280},
  year         = {2009},
}

@article{2191,
  abstract     = {By making use of the quantization rule of Raab and Friedrich [Phys. Rev. A 78, 022707 (2008)], we derive simple and accurate formulae for the number of rotational states supported by a weakly bound vibrational level of a diatomic molecule and the rotational constants of any such levels up to the threshold, and provide a criterion for determining whether a given weakly bound vibrational level is rotationless. The results depend solely on the long-range part of the molecular potential and are applicable to halo molecules. },
  author       = {Mikhail Lemeshko and Friedrich, Břetislav},
  journal      = {Physical Review A - Atomic, Molecular, and Optical Physics},
  number       = {5},
  publisher    = {American Physical Society},
  title        = {{Rotational and rotationless states of weakly bound molecules}},
  doi          = {10.1103/PhysRevA.79.050501},
  volume       = {79},
  year         = {2009},
}

@article{2192,
  abstract     = {We develop an analytic model of thermal state-to-state rotationally inelastic collisions of asymmetric-top molecules with closed-shell atoms in electric fields and apply it to the Ar-H2O collision system. The predicted cross sections as well as the steric asymmetry of the collisions show at fields up to 150 kV/cm characteristic field-dependent features which can be experimentally tested. Particularly suitable candidates for such tests are the 000 → 220 and 101→ 221 channels, arising from the relaxation of the field-free selection rules due to the hybridization of J states by the field. Averaging over the M' product channels is found to largely obliterate the orientation effects brought about by the field.},
  author       = {Mikhail Lemeshko and Friedrich, Břetislav},
  journal      = {Journal of Physical Chemistry A},
  number       = {52},
  pages        = {15055 -- 15063},
  publisher    = {American Chemical Society},
  title        = {{Model analysis of rotationally inelastic Ar + H2O scattering in an electric field}},
  doi          = {10.1021/jp9051598},
  volume       = {113},
  year         = {2009},
}

@article{2193,
  abstract     = {We show that weakly bound molecules can be probed by "shaking" in a pulsed nonresonant laser field. The field introduces a centrifugal term which expels the highest vibrational level from the potential that binds it. Our numerical simulations applied to the Rb2 and KRb Feshbach molecules indicate that shaking by feasible laser pulses can be used to accurately recover the square of the vibrational wave function and, by inversion, also the long-range part of the molecular potential.},
  author       = {Mikhail Lemeshko and Friedrich, Břetislav},
  journal      = {Physical Review Letters},
  number       = {5},
  publisher    = {American Physical Society},
  title        = {{Probing weakly bound molecules with nonresonant light}},
  doi          = {10.1103/PhysRevLett.103.053003},
  volume       = {103},
  year         = {2009},
}

@article{226,
  abstract     = {The Manin conjecture is established for a split singular del Pezzo surface of degree four, with singularity type A4.},
  author       = {Timothy Browning and Derenthal, Ulrich},
  journal      = {Annales de l'Institut Fourier},
  number       = {3},
  pages        = {1231 -- 1265},
  publisher    = {Association des Annales de l'Institut Fourier},
  title        = {{Manin's conjecture for a quartic del Pezzo surface with A4 singularity}},
  doi          = {10.5802/aif.2462},
  volume       = {59},
  year         = {2009},
}

@book{227,
  abstract     = {Winner of the Ferran Sunyer i Balaguer Prize 2009. First attempt to systematically survey the range of available tools from analytic number theory that can be applied to study the density of rational points on projective varieties. Designed to rapidly guide the reader to the many areas of ongoing research in the domain. Provides an extensive bibliography.},
  author       = {Browning, Timothy D},
  isbn         = {9-783-0346-0128-3},
  issn         = {2296-505X},
  pages        = {XIII, 160},
  publisher    = {Birkhäuser Basel},
  title        = {{Quantitative Arithmetic of Projective Varieties}},
  doi          = {10.1007/978-3-0346-0129-0},
  volume       = {277},
  year         = {2009},
}