[{"article_processing_charge":"Yes (in subscription journal)","_id":"20755","OA_type":"hybrid","quality_controlled":"1","ddc":["540"],"status":"public","publication":"Chemical Communications","OA_place":"publisher","oa":1,"page":"16993-16996","publisher":"Royal Society of Chemistry","intvolume":"        61","publication_status":"published","date_created":"2025-12-09T14:22:09Z","day":"06","issue":"87","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"url":"https://doi.org/10.1039/D5CC03194J","open_access":"1"}],"doi":"10.1039/d5cc03194j","month":"10","scopus_import":"1","language":[{"iso":"eng"}],"extern":"1","article_type":"original","volume":61,"date_published":"2025-10-06T00:00:00Z","has_accepted_license":"1","title":"Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions","year":"2025","date_updated":"2026-03-16T08:31:23Z","type":"journal_article","publication_identifier":{"eissn":["1364-548X"],"issn":["1359-7345"]},"citation":{"short":"S. Moon, J. Reisenbauer, A.-S.K. Paschke, A. Scotto, L. Terraneo, N. Brenner, Q. Lefebvre, T.C. Fessard, B. Morandi, Chemical Communications 61 (2025) 16993–16996.","mla":"Moon, Sooyeon, et al. “Efficient Optimization and Synthesis of Diverse Azaarenes via Nitrogen Atom Insertion under Continuous Flow Conditions.” <i>Chemical Communications</i>, vol. 61, no. 87, Royal Society of Chemistry, 2025, pp. 16993–96, doi:<a href=\"https://doi.org/10.1039/d5cc03194j\">10.1039/d5cc03194j</a>.","ieee":"S. Moon <i>et al.</i>, “Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions,” <i>Chemical Communications</i>, vol. 61, no. 87. Royal Society of Chemistry, pp. 16993–16996, 2025.","ista":"Moon S, Reisenbauer J, Paschke A-SK, Scotto A, Terraneo L, Brenner N, Lefebvre Q, Fessard TC, Morandi B. 2025. Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions. Chemical Communications. 61(87), 16993–16996.","chicago":"Moon, Sooyeon, Julia Reisenbauer, Ann-Sophie K. Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, Quentin Lefebvre, Thomas C. Fessard, and Bill Morandi. “Efficient Optimization and Synthesis of Diverse Azaarenes via Nitrogen Atom Insertion under Continuous Flow Conditions.” <i>Chemical Communications</i>. Royal Society of Chemistry, 2025. <a href=\"https://doi.org/10.1039/d5cc03194j\">https://doi.org/10.1039/d5cc03194j</a>.","ama":"Moon S, Reisenbauer J, Paschke A-SK, et al. Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions. <i>Chemical Communications</i>. 2025;61(87):16993-16996. doi:<a href=\"https://doi.org/10.1039/d5cc03194j\">10.1039/d5cc03194j</a>","apa":"Moon, S., Reisenbauer, J., Paschke, A.-S. K., Scotto, A., Terraneo, L., Brenner, N., … Morandi, B. (2025). Efficient optimization and synthesis of diverse azaarenes via nitrogen atom insertion under continuous flow conditions. <i>Chemical Communications</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d5cc03194j\">https://doi.org/10.1039/d5cc03194j</a>"},"abstract":[{"text":"We report the development of a continuous flow approach to nitrogen atom insertion. The setup is modular, enabling the rapid optimization of reaction conditions for a wide range of substrates. The milder reaction conditions led to an improved substrate scope and functional group tolerance compared to batch conditions. The reactions can also be safely scaled up to preparative scale.","lang":"eng"}],"oa_version":"Published Version","author":[{"full_name":"Moon, Sooyeon","last_name":"Moon","first_name":"Sooyeon"},{"id":"51d862e9-36ee-11f0-86d3-8534c85a5496","full_name":"Reisenbauer, Julia","last_name":"Reisenbauer","first_name":"Julia"},{"full_name":"Paschke, Ann-Sophie K.","first_name":"Ann-Sophie K.","last_name":"Paschke"},{"first_name":"Alessandro","last_name":"Scotto","full_name":"Scotto, Alessandro"},{"last_name":"Terraneo","first_name":"Luca","full_name":"Terraneo, Luca"},{"full_name":"Brenner, Niklas","first_name":"Niklas","last_name":"Brenner"},{"last_name":"Lefebvre","first_name":"Quentin","full_name":"Lefebvre, Quentin"},{"full_name":"Fessard, Thomas C.","last_name":"Fessard","first_name":"Thomas C."},{"last_name":"Morandi","first_name":"Bill","full_name":"Morandi, Bill"}]},{"citation":{"apa":"Horwitz, M. A., Al-Ahmad, R., Bai, X., Balletti, M., Bellotti, P., Ben-Tal, Y., … Wuitschik, G. (2025). Reimagining advanced chemistry education: A community-based approach to course design for modern learners. <i>Journal of Chemical Education</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">https://doi.org/10.1021/acs.jchemed.5c00555</a>","ama":"Horwitz MA, Al-Ahmad R, Bai X, et al. Reimagining advanced chemistry education: A community-based approach to course design for modern learners. <i>Journal of Chemical Education</i>. 2025;102(9):3777-3783. doi:<a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">10.1021/acs.jchemed.5c00555</a>","chicago":"Horwitz, Matthew A., Reem Al-Ahmad, Xingfeng Bai, Matteo Balletti, Peter Bellotti, Yael Ben-Tal, Mark W. Campbell, et al. “Reimagining Advanced Chemistry Education: A Community-Based Approach to Course Design for Modern Learners.” <i>Journal of Chemical Education</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">https://doi.org/10.1021/acs.jchemed.5c00555</a>.","ista":"Horwitz MA, Al-Ahmad R, Bai X, Balletti M, Bellotti P, Ben-Tal Y, Campbell MW, Cheasty K, Crossley SWM, Day CS, Deneny PJ, Forbes KC, Gogarnoiu ES, Grant PS, Halder R, Harris GR, Hernández-Lladó P, Jouanneau M, Jost V, Kutateladze DA, Laudadio G, Liu C, Looby AP, Maestro A, McCallum T, Palkowitz MD, Paolillo JM, Perry MWD, Reisenbauer J, Reyes C, Sharma HA, Sheong FK, Thoma B, Tran AV, Tran DN, Aguilar Troyano FJ, Verheyen T, Walsh MP, Wagner A, Wearing ER, Wuitschik G. 2025. Reimagining advanced chemistry education: A community-based approach to course design for modern learners. Journal of Chemical Education. 102(9), 3777–3783.","mla":"Horwitz, Matthew A., et al. “Reimagining Advanced Chemistry Education: A Community-Based Approach to Course Design for Modern Learners.” <i>Journal of Chemical Education</i>, vol. 102, no. 9, American Chemical Society, 2025, pp. 3777–83, doi:<a href=\"https://doi.org/10.1021/acs.jchemed.5c00555\">10.1021/acs.jchemed.5c00555</a>.","ieee":"M. A. Horwitz <i>et al.</i>, “Reimagining advanced chemistry education: A community-based approach to course design for modern learners,” <i>Journal of Chemical Education</i>, vol. 102, no. 9. American Chemical Society, pp. 3777–3783, 2025.","short":"M.A. Horwitz, R. Al-Ahmad, X. Bai, M. Balletti, P. Bellotti, Y. Ben-Tal, M.W. Campbell, K. Cheasty, S.W.M. Crossley, C.S. Day, P.J. Deneny, K.C. Forbes, E.S. Gogarnoiu, P.S. Grant, R. Halder, G.R. Harris, P. Hernández-Lladó, M. Jouanneau, V. Jost, D.A. Kutateladze, G. Laudadio, C. Liu, A.P. Looby, A. Maestro, T. McCallum, M.D. Palkowitz, J.M. Paolillo, M.W.D. Perry, J. Reisenbauer, C. Reyes, H.A. Sharma, F.K. Sheong, B. Thoma, A.V. Tran, D.N. Tran, F.J. Aguilar Troyano, T. Verheyen, M.P. Walsh, A. Wagner, E.R. Wearing, G. Wuitschik, Journal of Chemical Education 102 (2025) 3777–3783."},"abstract":[{"lang":"eng","text":"Chemistry education at the graduate level and beyond faces the formidable challenge of a boundless and constantly expanding frontier of knowledge on many fronts. While modern learners have an increasingly broad range of resources available at their disposal (including open access text-based references, online videos, training problems, and other digital learning materials), there are comparatively fewer such materials aimed at the highest levels of study. With the goal of producing widely accessible graduate-level learning content, we created a community-based approach to online course design that is easily digestible to meet the expectations of modern learners. Herein, we report the development of an open access Advanced Organic Chemistry video-based online course and several other specialized minicourses using the Synthesis Workshop YouTube channel."}],"author":[{"full_name":"Horwitz, Matthew A.","last_name":"Horwitz","first_name":"Matthew A."},{"full_name":"Al-Ahmad, Reem","first_name":"Reem","last_name":"Al-Ahmad"},{"last_name":"Bai","first_name":"Xingfeng","full_name":"Bai, Xingfeng"},{"full_name":"Balletti, Matteo","first_name":"Matteo","last_name":"Balletti"},{"first_name":"Peter","last_name":"Bellotti","full_name":"Bellotti, Peter"},{"full_name":"Ben-Tal, Yael","first_name":"Yael","last_name":"Ben-Tal"},{"last_name":"Campbell","first_name":"Mark W.","full_name":"Campbell, Mark W."},{"last_name":"Cheasty","first_name":"Kathleen","full_name":"Cheasty, Kathleen"},{"first_name":"Steven W. M.","last_name":"Crossley","full_name":"Crossley, Steven W. M."},{"last_name":"Day","first_name":"Craig S.","full_name":"Day, Craig S."},{"full_name":"Deneny, Patrick J.","last_name":"Deneny","first_name":"Patrick J."},{"first_name":"Katherine C.","last_name":"Forbes","full_name":"Forbes, Katherine C."},{"last_name":"Gogarnoiu","first_name":"Emma S.","full_name":"Gogarnoiu, Emma S."},{"first_name":"Phillip S.","last_name":"Grant","full_name":"Grant, Phillip S."},{"first_name":"Riya","last_name":"Halder","full_name":"Halder, Riya"},{"first_name":"Georgia R.","last_name":"Harris","full_name":"Harris, Georgia R."},{"full_name":"Hernández-Lladó, Pol","last_name":"Hernández-Lladó","first_name":"Pol"},{"first_name":"Morgan","last_name":"Jouanneau","full_name":"Jouanneau, Morgan"},{"full_name":"Jost, Vera","last_name":"Jost","first_name":"Vera"},{"last_name":"Kutateladze","first_name":"Dennis A.","full_name":"Kutateladze, Dennis A."},{"full_name":"Laudadio, Gabriele","first_name":"Gabriele","last_name":"Laudadio"},{"full_name":"Liu, Chun","first_name":"Chun","last_name":"Liu"},{"full_name":"Looby, Aidan P.","first_name":"Aidan P.","last_name":"Looby"},{"full_name":"Maestro, Aitor","last_name":"Maestro","first_name":"Aitor"},{"full_name":"McCallum, Terry","first_name":"Terry","last_name":"McCallum"},{"full_name":"Palkowitz, Maximilian D.","first_name":"Maximilian D.","last_name":"Palkowitz"},{"last_name":"Paolillo","first_name":"Joshua M.","full_name":"Paolillo, Joshua M."},{"last_name":"Perry","first_name":"Matthew W. D.","full_name":"Perry, Matthew W. D."},{"full_name":"Reisenbauer, Julia","id":"51d862e9-36ee-11f0-86d3-8534c85a5496","first_name":"Julia","last_name":"Reisenbauer"},{"full_name":"Reyes, Cesar","last_name":"Reyes","first_name":"Cesar"},{"full_name":"Sharma, Hayden A.","first_name":"Hayden A.","last_name":"Sharma"},{"full_name":"Sheong, Fu Kit","last_name":"Sheong","first_name":"Fu Kit"},{"first_name":"Benjamin","last_name":"Thoma","full_name":"Thoma, Benjamin"},{"full_name":"Tran, Andrew V.","first_name":"Andrew V.","last_name":"Tran"},{"full_name":"Tran, Duc N.","first_name":"Duc N.","last_name":"Tran"},{"last_name":"Aguilar Troyano","first_name":"Francisco José","full_name":"Aguilar Troyano, Francisco José"},{"full_name":"Verheyen, Thomas","last_name":"Verheyen","first_name":"Thomas"},{"last_name":"Walsh","first_name":"Mark P.","full_name":"Walsh, Mark P."},{"full_name":"Wagner, Alicia","last_name":"Wagner","first_name":"Alicia"},{"full_name":"Wearing, Emily R.","first_name":"Emily R.","last_name":"Wearing"},{"first_name":"Georg","last_name":"Wuitschik","full_name":"Wuitschik, Georg"}],"oa_version":"None","year":"2025","title":"Reimagining advanced chemistry education: A community-based approach to course design for modern learners","type":"journal_article","publication_identifier":{"issn":["0021-9584"],"eissn":["1938-1328"]},"date_updated":"2025-12-16T12:13:49Z","article_type":"original","language":[{"iso":"eng"}],"extern":"1","date_published":"2025-08-15T00:00:00Z","volume":102,"doi":"10.1021/acs.jchemed.5c00555","month":"08","scopus_import":"1","issue":"9","day":"15","date_created":"2025-12-09T14:27:11Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","intvolume":"       102","status":"public","publication":"Journal of Chemical Education","page":"3777-3783","publisher":"American Chemical Society","_id":"20767","OA_type":"closed access","article_processing_charge":"No","quality_controlled":"1"},{"corr_author":"1","department":[{"_id":"BeVi"}],"file_date_updated":"2025-12-11T11:00:53Z","has_accepted_license":"1","publisher":"Institute of Science and Technology Austria","oa":1,"file":[{"date_created":"2025-12-11T10:47:15Z","file_size":4575,"checksum":"251e7aab01917c2ad2fbccf465492ea1","file_name":"Perl_scripts.zip","success":1,"creator":"llayanaf","relation":"main_file","file_id":"20799","date_updated":"2025-12-11T10:47:15Z","content_type":"application/zip","access_level":"open_access"},{"file_name":"Supplementary_Datasets.zip","checksum":"daf1c03149dd170b14e5c8e109ee3c77","file_size":19052849,"date_created":"2025-12-11T10:52:17Z","success":1,"file_id":"20800","relation":"main_file","creator":"llayanaf","access_level":"open_access","date_updated":"2025-12-11T10:52:17Z","content_type":"application/zip"},{"success":1,"checksum":"658d6e95a361b0a3db058b7b4e1733d4","file_size":566476,"date_created":"2025-12-11T10:52:11Z","file_name":"Supplementary_Tables.zip","date_updated":"2025-12-11T10:52:11Z","content_type":"application/zip","access_level":"open_access","file_id":"20801","relation":"main_file","creator":"llayanaf"},{"creator":"llayanaf","relation":"main_file","file_id":"20802","content_type":"text/plain","date_updated":"2025-12-11T11:00:53Z","access_level":"open_access","file_size":1204,"date_created":"2025-12-11T11:00:53Z","checksum":"2a2b92eb9fade0015719190596a8c5b7","file_name":"README.txt","success":1}],"date_published":"2025-12-01T00:00:00Z","status":"public","_id":"20780","article_processing_charge":"No","month":"12","doi":"10.15479/AT-ISTA-20780","author":[{"last_name":"Layana Franco","orcid":"0000-0002-1253-6297","first_name":"Lorena Alexandra","id":"02814589-eb8f-11eb-b029-a70074f3f18f","full_name":"Layana Franco, Lorena Alexandra"},{"last_name":"Toups","first_name":"Melissa A","orcid":"0000-0002-9752-7380","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","full_name":"Toups, Melissa A"},{"full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4579-8306","first_name":"Beatriz","last_name":"Vicoso"}],"oa_version":"Published Version","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","citation":{"short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, (2025).","ista":"Layana Franco LA, Toups MA, Vicoso B. 2025. Causes and consequences of sex-chromosome turnovers in Diptera, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>.","chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">https://doi.org/10.15479/AT-ISTA-20780</a>.","mla":"Layana Franco, Lorena Alexandra, et al. <i>Causes and Consequences of Sex-Chromosome Turnovers in Diptera</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>.","ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Causes and consequences of sex-chromosome turnovers in Diptera.” Institute of Science and Technology Austria, 2025.","ama":"Layana Franco LA, Toups MA, Vicoso B. Causes and consequences of sex-chromosome turnovers in Diptera. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20780\">10.15479/AT-ISTA-20780</a>","apa":"Layana Franco, L. A., Toups, M. A., &#38; Vicoso, B. (2025). Causes and consequences of sex-chromosome turnovers in Diptera. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20780\">https://doi.org/10.15479/AT-ISTA-20780</a>"},"abstract":[{"lang":"eng","text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analysed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on the F element (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male-achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes."}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_created":"2025-12-10T23:40:14Z","type":"research_data","acknowledged_ssus":[{"_id":"ScienComp"}],"date_updated":"2026-06-10T08:27:48Z","year":"2025","keyword":["Schizophora","sex chromosomes","sex-chromosome turnover","Diptera","genomic features","out-of-X movement."],"title":"Causes and consequences of sex-chromosome turnovers in Diptera"},{"publisher":"National Academy of Sciences","department":[{"_id":"CaMu"}],"file":[{"creator":"dernst","relation":"main_file","file_id":"20822","access_level":"open_access","content_type":"application/pdf","date_updated":"2025-12-15T09:17:33Z","file_name":"2025_PNAS_Bao.pdf","date_created":"2025-12-15T09:17:33Z","file_size":30890293,"checksum":"093a8685170e4a1de9176f68ee449493","success":1}],"oa":1,"OA_place":"publisher","publication":"Proceedings of the National Academy of Sciences","status":"public","ddc":["550"],"external_id":{"pmid":["41284872"]},"quality_controlled":"1","_id":"20795","article_processing_charge":"Yes (in subscription journal)","OA_type":"hybrid","acknowledgement":"J.B. acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant agreement No. 101034413). S.B. acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Project Mesoscale organization of tropical convection, grant agreement No 101098063). D.T. acknowledges funding from the Japan Society for the Promotion of Science (JSPS) (Project JSPS Grants-in-Aid for Scientiﬁc Research, grant No. JP24K22893). C.M. gratefully acknowledges funding from the ERC under the European Union’s Horizon 2020 research and innovation program (Project organisation of CLoUdS, and implications for Tropical cyclones and for the Energetics of the tropics, in current and in a waRming climate, grant agreement No. 805041). We thank Martin Singh, Steven Sherwood, Bjorn Stevens, and Lokahith Agasthya for helpful discussions. JSPS Core-to-Core Program, “International Core-to-Core Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"48","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"pmid":1,"day":"02","date_created":"2025-12-11T10:41:13Z","publication_status":"published","intvolume":"       122","project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"},{"name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","grant_number":"805041","_id":"629205d8-2b32-11ec-9570-e1356ff73576","call_identifier":"H2020"}],"file_date_updated":"2025-12-15T09:17:33Z","has_accepted_license":"1","corr_author":"1","date_published":"2025-12-02T00:00:00Z","volume":122,"ec_funded":1,"PlanS_conform":"1","APC_amount":"5651,35 EUR","article_type":"original","language":[{"iso":"eng"}],"scopus_import":"1","month":"12","doi":"10.1073/pnas.2511549122","author":[{"first_name":"Jiawei","last_name":"Bao","full_name":"Bao, Jiawei","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160"},{"full_name":"Bony, Sandrine","first_name":"Sandrine","last_name":"Bony"},{"first_name":"Daisuke","last_name":"Takasuka","full_name":"Takasuka, Daisuke"},{"full_name":"Muller, Caroline J","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","orcid":"0000-0001-5836-5350","first_name":"Caroline J","last_name":"Muller"}],"oa_version":"Published Version","abstract":[{"lang":"eng","text":"The tropical climate variability is characterized by various oscillations across a range of timescales. Oscillations that imprint the tropical mean state are generally attributed to slow processes, such as the seasonal cycle or interannual variability. Here, we identify a pronounced tropics-wide intraseasonal oscillation (TWISO) in satellite observations and reanalyses. This oscillation, with a period of 30 to 60 d, is evident across multiple variables and involves interactions between convection, radiation, surface fluxes, and large-scale circulation. It is primarily manifested as convective perturbations in the tropical Indo-Pacific warm pool accompanied by oscillations in the large-scale tropical overturning circulation. Here, we examine the relationship between TWISO, the Madden–Julian Oscillation (MJO), and the instability of radiative-convective equilibrium. Certain phases of TWISO coincide with specific phases of the MJO, suggesting a potential connection between the two. However, although the MJO can amplify the oscillation amplitude of TWISO, it is not essential for TWISO to occur. Finally, due to its broad manifestation across the tropics, TWISO potentially exerts widespread influence on tropical weather and climate at regional scales."}],"article_number":"e2511549122","citation":{"short":"J. Bao, S. Bony, D. Takasuka, C.J. Muller, Proceedings of the National Academy of Sciences 122 (2025).","chicago":"Bao, Jiawei, Sandrine Bony, Daisuke Takasuka, and Caroline J Muller. “Tropics-Wide Intraseasonal Oscillations.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2511549122\">https://doi.org/10.1073/pnas.2511549122</a>.","ista":"Bao J, Bony S, Takasuka D, Muller CJ. 2025. Tropics-wide intraseasonal oscillations. Proceedings of the National Academy of Sciences. 122(48), e2511549122.","ieee":"J. Bao, S. Bony, D. Takasuka, and C. J. Muller, “Tropics-wide intraseasonal oscillations,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 48. National Academy of Sciences, 2025.","mla":"Bao, Jiawei, et al. “Tropics-Wide Intraseasonal Oscillations.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 48, e2511549122, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2511549122\">10.1073/pnas.2511549122</a>.","ama":"Bao J, Bony S, Takasuka D, Muller CJ. Tropics-wide intraseasonal oscillations. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(48). doi:<a href=\"https://doi.org/10.1073/pnas.2511549122\">10.1073/pnas.2511549122</a>","apa":"Bao, J., Bony, S., Takasuka, D., &#38; Muller, C. J. (2025). Tropics-wide intraseasonal oscillations. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2511549122\">https://doi.org/10.1073/pnas.2511549122</a>"},"publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"type":"journal_article","date_updated":"2026-05-20T08:11:56Z","year":"2025","related_material":{"link":[{"url":"https://ista.ac.at/en/news/hidden-in-plain-sight/","relation":"press_release","description":"News on ISTA website"}]},"title":"Tropics-wide intraseasonal oscillations"},{"date_published":"2025-11-25T00:00:00Z","volume":16,"PlanS_conform":"1","project":[{"grant_number":"F8810","_id":"34ae1506-11ca-11ed-8bc3-c14f4c474396","name":"The highjacking of meiosis for asexual reproduction"}],"has_accepted_license":"1","file_date_updated":"2025-12-15T09:25:51Z","language":[{"iso":"eng"}],"article_type":"original","scopus_import":"1","doi":"10.1038/s41467-025-65420-9","month":"11","oa_version":"Published Version","author":[{"first_name":"Dimitra","last_name":"Paouneskou","full_name":"Paouneskou, Dimitra"},{"full_name":"Baudrimont, Antoine","last_name":"Baudrimont","first_name":"Antoine"},{"full_name":"Kelemen, Réka K","id":"48D3F8DE-F248-11E8-B48F-1D18A9856A87","first_name":"Réka K","orcid":"0000-0002-8489-9281","last_name":"Kelemen"},{"id":"0B46FACA-A8E1-11E9-9BD3-79D1E5697425","full_name":"Elkrewi, Marwan N","last_name":"Elkrewi","orcid":"0000-0002-5328-7231","first_name":"Marwan N"},{"full_name":"Graf, Angela","last_name":"Graf","first_name":"Angela"},{"full_name":"Moukbel Ali Aldawla, Shehab","last_name":"Moukbel Ali Aldawla","first_name":"Shehab"},{"last_name":"Kölbl","first_name":"Claudia","full_name":"Kölbl, Claudia"},{"last_name":"Tiemann-Boege","first_name":"Irene","full_name":"Tiemann-Boege, Irene"},{"last_name":"Vicoso","orcid":"0000-0002-4579-8306","first_name":"Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz"},{"full_name":"Jantsch, Verena","last_name":"Jantsch","first_name":"Verena"}],"abstract":[{"lang":"eng","text":"Rapid prophase chromosome movements ensure faithful alignment of the parental homologous chromosomes and successful synapsis formation during meiosis. These movements are driven by cytoplasmic forces transmitted to the nuclear periphery, where chromosome ends are attached through transmembrane proteins. During many developmental stages a specific genome architecture with chromatin nuclear periphery contacts mediates specific gene expression. Whether chromatin is removed from the nuclear periphery as a consequence of chromosome motions or by a specific mechanism is not fully understood. Here, we identify a mechanism to remove chromatin from the nuclear periphery through vaccinia related kinase (VRK-1)–dependent phosphorylation of Barrier to Autointegration Factor 1 (BAF-1) in Caenorhabditis elegans early prophase of meiosis. Interfering with chromatin removal delays chromosome pairing, impairs synapsis, produces oocytes with abnormal chromosomes and elevated apoptosis. Long read sequencing reveals deletions and duplications in offspring lacking VRK-1 underscoring the importance of the BAF-1–VRK-1 module in preserving genome stability in gametes during rapid chromosome movements."}],"article_number":"10446","citation":{"ama":"Paouneskou D, Baudrimont A, Kelemen RK, et al. BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-65420-9\">10.1038/s41467-025-65420-9</a>","apa":"Paouneskou, D., Baudrimont, A., Kelemen, R. K., Elkrewi, M. N., Graf, A., Moukbel Ali Aldawla, S., … Jantsch, V. (2025). BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-65420-9\">https://doi.org/10.1038/s41467-025-65420-9</a>","short":"D. Paouneskou, A. Baudrimont, R.K. Kelemen, M.N. Elkrewi, A. Graf, S. Moukbel Ali Aldawla, C. Kölbl, I. Tiemann-Boege, B. Vicoso, V. Jantsch, Nature Communications 16 (2025).","chicago":"Paouneskou, Dimitra, Antoine Baudrimont, Réka K Kelemen, Marwan N Elkrewi, Angela Graf, Shehab Moukbel Ali Aldawla, Claudia Kölbl, Irene Tiemann-Boege, Beatriz Vicoso, and Verena Jantsch. “BAF-1–VRK-1 Mediated Release of Meiotic Chromosomes from the Nuclear Periphery Is Important for Genome Integrity.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-65420-9\">https://doi.org/10.1038/s41467-025-65420-9</a>.","ista":"Paouneskou D, Baudrimont A, Kelemen RK, Elkrewi MN, Graf A, Moukbel Ali Aldawla S, Kölbl C, Tiemann-Boege I, Vicoso B, Jantsch V. 2025. BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity. Nature Communications. 16, 10446.","ieee":"D. Paouneskou <i>et al.</i>, “BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","mla":"Paouneskou, Dimitra, et al. “BAF-1–VRK-1 Mediated Release of Meiotic Chromosomes from the Nuclear Periphery Is Important for Genome Integrity.” <i>Nature Communications</i>, vol. 16, 10446, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-65420-9\">10.1038/s41467-025-65420-9</a>."},"date_updated":"2025-12-15T09:28:37Z","publication_identifier":{"eissn":["2041-1723"]},"type":"journal_article","title":"BAF-1–VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity","year":"2025","file":[{"success":1,"file_name":"2025_NatureComm_Paouneskou.pdf","file_size":8096309,"date_created":"2025-12-15T09:25:51Z","checksum":"a952f7ea050242b79008540de49a0e61","access_level":"open_access","date_updated":"2025-12-15T09:25:51Z","content_type":"application/pdf","creator":"dernst","relation":"main_file","file_id":"20823"}],"oa":1,"publisher":"Springer Nature","department":[{"_id":"BeVi"}],"publication":"Nature Communications","status":"public","OA_place":"publisher","ddc":["570"],"quality_controlled":"1","external_id":{"pmid":["41290579"]},"acknowledgement":"We are grateful to Monique Zetka, Nicola Silva, and Yumi Kim, Needhi Bhalla, George Krohne and Rueyling Lin for providing reagents; Scott Kennedy for sharing the multiplexed FISH library; and members of the Max Perutz Labs’ BioOptics facility (Irmgard Fischer, Josef Gotzmann, Thomas Peterbauer, Clara Bodner, and Nick Wedige) for training and support in image acquisition. We also thank the members of the NGS facility at the Vienna Biocenter. This work was funded by the Austrian Science Fund (FWF) SFB projects F 8805-B (VJ), https://doi.org/10.55776/F88, F 8809-B (ITB), and F8810-B (BV). We are also grateful to members of the V. Jantsch laboratory for helpful discussions. Some strains were provided by the Caenorhabditis Genetics Center, which is funded by the National Institutes of Health Office of Research Infrastructure Programs (P40OD010440).","OA_type":"gold","_id":"20796","article_processing_charge":"Yes","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"date_created":"2025-12-11T10:45:06Z","day":"25","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"intvolume":"        16","DOAJ_listed":"1","publication_status":"published"},{"year":"2025","title":"Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants","type":"journal_article","publication_identifier":{"issn":["1474-7596"],"eissn":["1474-760X"]},"date_updated":"2025-12-15T13:19:41Z","citation":{"apa":"Robertson, J. A., Bajzik, J., Vernardis, S., Chybowska, A. D., Mccartney, D. L., Grauslys, A., … Marioni, R. E. (2025). Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. <i>Genome Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s13059-025-03892-0\">https://doi.org/10.1186/s13059-025-03892-0</a>","ama":"Robertson JA, Bajzik J, Vernardis S, et al. Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. <i>Genome Biology</i>. 2025;26. doi:<a href=\"https://doi.org/10.1186/s13059-025-03892-0\">10.1186/s13059-025-03892-0</a>","ieee":"J. A. Robertson <i>et al.</i>, “Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants,” <i>Genome Biology</i>, vol. 26. Springer Nature, 2025.","mla":"Robertson, Josephine A., et al. “Methylome-Wide Association Studies and Epigenetic Biomarker Development for 133 Mass Spectrometry-Assessed Circulating Proteins in 14,671 Generation Scotland Participants.” <i>Genome Biology</i>, vol. 26, 417, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1186/s13059-025-03892-0\">10.1186/s13059-025-03892-0</a>.","chicago":"Robertson, Josephine A., Jakub Bajzik, Spyros Vernardis, Aleksandra D. Chybowska, Daniel L. Mccartney, Arturas Grauslys, Jure Mur, et al. “Methylome-Wide Association Studies and Epigenetic Biomarker Development for 133 Mass Spectrometry-Assessed Circulating Proteins in 14,671 Generation Scotland Participants.” <i>Genome Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1186/s13059-025-03892-0\">https://doi.org/10.1186/s13059-025-03892-0</a>.","ista":"Robertson JA, Bajzik J, Vernardis S, Chybowska AD, Mccartney DL, Grauslys A, Mur J, Smith HM, Campbell A, Drake C, Grant H, Pearce J, Russ TC, Adkin P, White M, Brigden C, Messner CB, Porteous DJ, Hayward C, Cox SR, Zelezniak A, Ralser M, Robinson MR, Marioni RE. 2025. Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants. Genome Biology. 26, 417.","short":"J.A. Robertson, J. Bajzik, S. Vernardis, A.D. Chybowska, D.L. Mccartney, A. Grauslys, J. Mur, H.M. Smith, A. Campbell, C. Drake, H. Grant, J. Pearce, T.C. Russ, P. Adkin, M. White, C. Brigden, C.B. Messner, D.J. Porteous, C. Hayward, S.R. Cox, A. Zelezniak, M. Ralser, M.R. Robinson, R.E. Marioni, Genome Biology 26 (2025)."},"article_number":"417","abstract":[{"lang":"eng","text":"Background: DNA methylation (DNAm) can regulate gene expression, and its genome-wide patterns (epigenetic scores or EpiScores) can act as biomarkers for complex traits. The relative stability of methylation profiles may enable better assessment of chronic exposures compared to single time-point protein measures. We present the first large-scale epigenetic study of the highly-abundant serum proteome measured via ultra-high throughput mass spectrometry in 14,671 samples from the Generation Scotland cohort. We further demonstrate the first large-scale comparison of protein EpiScores and their respective proteins as predictors of incident cardiovascular disease.\r\n\r\nResults: Marginal epigenome-wide association models, adjusting for age, sex, measurement batch, estimated white cell proportions, BMI, smoking and methylation principal components, reveal 15,855 significant CpG – protein associations across 125 of 133 proteins PBonferroni < 2.71 × 10-10. Bayesian epigenome-wide association studies of the same 133 proteins reveal 697 CpG-Protein associations (posterior inclusion probability > 0.95). 112 protein EpiScores correlate significantly with their respective protein in a holdout test-set. Of these, sixteen associate significantly with incident all-cause cardiovascular disease (Nevents=191) compared to one measured protein.\r\n\r\nConclusions: We highlight a complex interplay between the blood-based methylome and proteome. Importantly, we show that protein EpiScores correlate with measured proteins and demonstrate that the, as-yet understudied, high-abundance proteome may yield clinically relevant biomarkers. The protein EpiScores demonstrate more significant associations with cardiovascular disease than directly measured proteins, suggesting their potential as clinical biomarkers for monitoring or predicting disease risk. We suggest that biomarker development could be enhanced by the consideration of protein EpiScores alongside measured proteins."}],"author":[{"full_name":"Robertson, Josephine A.","last_name":"Robertson","first_name":"Josephine A."},{"id":"b995e25b-8c4b-11ed-a6d8-f71b7bcd6122","full_name":"Bajzik, Jakub","last_name":"Bajzik","first_name":"Jakub"},{"first_name":"Spyros","last_name":"Vernardis","full_name":"Vernardis, Spyros"},{"full_name":"Chybowska, Aleksandra D.","last_name":"Chybowska","first_name":"Aleksandra D."},{"full_name":"Mccartney, Daniel L.","first_name":"Daniel L.","last_name":"Mccartney"},{"full_name":"Grauslys, Arturas","last_name":"Grauslys","first_name":"Arturas"},{"first_name":"Jure","last_name":"Mur","full_name":"Mur, Jure"},{"full_name":"Smith, Hannah M.","last_name":"Smith","first_name":"Hannah M."},{"full_name":"Campbell, Archie","last_name":"Campbell","first_name":"Archie"},{"full_name":"Drake, Camilla","last_name":"Drake","first_name":"Camilla"},{"full_name":"Grant, Hannah","first_name":"Hannah","last_name":"Grant"},{"full_name":"Pearce, Jamie","last_name":"Pearce","first_name":"Jamie"},{"last_name":"Russ","first_name":"Tom C.","full_name":"Russ, Tom C."},{"first_name":"Poppy","last_name":"Adkin","full_name":"Adkin, Poppy"},{"full_name":"White, Matthew","last_name":"White","first_name":"Matthew"},{"full_name":"Brigden, Charles","last_name":"Brigden","first_name":"Charles"},{"full_name":"Messner, Christoph B.","first_name":"Christoph B.","last_name":"Messner"},{"full_name":"Porteous, David J.","last_name":"Porteous","first_name":"David J."},{"last_name":"Hayward","first_name":"Caroline","full_name":"Hayward, Caroline"},{"full_name":"Cox, Simon R.","first_name":"Simon R.","last_name":"Cox"},{"full_name":"Zelezniak, Aleksej","first_name":"Aleksej","last_name":"Zelezniak"},{"full_name":"Ralser, Markus","last_name":"Ralser","first_name":"Markus"},{"last_name":"Robinson","first_name":"Matthew Richard","orcid":"0000-0001-8982-8813","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","full_name":"Robinson, Matthew Richard"},{"last_name":"Marioni","first_name":"Riccardo E.","full_name":"Marioni, Riccardo E."}],"oa_version":"Published Version","doi":"10.1186/s13059-025-03892-0","month":"12","scopus_import":"1","article_type":"original","language":[{"iso":"eng"}],"file_date_updated":"2025-12-15T13:18:07Z","has_accepted_license":"1","date_published":"2025-12-08T00:00:00Z","volume":26,"publication_status":"published","intvolume":"        26","DOAJ_listed":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_created":"2025-12-14T23:02:04Z","day":"08","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"Yes","_id":"20816","OA_type":"gold","acknowledgement":"Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006] and is currently supported by the Wellcome Trust [216767/Z/19/Z]. Genotyping of the Generation Scotland samples was carried out by the Genetics Core Laboratory at the Edinburgh Clinical Research Facility, University of Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” (STRADL) Reference 104036/Z/14/Z). The DNA methylation profiling and analysis was supported by Wellcome Investigator Award 220857/Z/20/Z and Grant 104036/Z/14/Z (PI: Prof AM McIntosh) and through funding from NARSAD (Ref: 27404; awardee: Dr DM Howard) and the Royal College of Physicians of Edinburgh (Sim Fellowship; Awardee: Prof HC Whalley).\r\nJAR is a University of Edinburgh Clinical Academic Track PhD student, supported by the Wellcome Trust (319878/Z/24/Z). ADC was supported by a Medical Research Council PhD Studentship in Precision Medicine with funding from the Medical Research Council Doctoral Training Program and the University of Edinburgh College of Medicine and Veterinary Medicine. HMS is a student on the University of Edinburgh Translational Neuroscience PhD programme funded by the Wellcome Trust (218493/Z/19/Z). CH was funded by MRC Human Genetics Unit program (QTL in Health and Disease) (grant U.MC_UU_00007/10). S.R.C. is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (221890/Z/20/Z). JM and REM were supported by Alzheimer’s Society project grant AS-PG-19b-010.","quality_controlled":"1","external_id":{"pmid":["41361833"]},"ddc":["570"],"OA_place":"publisher","status":"public","publication":"Genome Biology","department":[{"_id":"MaRo"}],"publisher":"Springer Nature","oa":1,"file":[{"success":1,"file_name":"2025_GenomeBiology_Robertson.pdf","file_size":2206991,"date_created":"2025-12-15T13:18:07Z","checksum":"7c92919af1b5820d01e91e08906a411f","access_level":"open_access","date_updated":"2025-12-15T13:18:07Z","content_type":"application/pdf","creator":"dernst","relation":"main_file","file_id":"20825"}]},{"page":"48962-48973","department":[{"_id":"FrLo"}],"publisher":"ML Research Press","oa":1,"file":[{"file_id":"20827","relation":"main_file","creator":"dernst","content_type":"application/pdf","date_updated":"2025-12-16T12:21:49Z","access_level":"open_access","checksum":"933cb673fb41416f537278fb990df6c3","file_size":993381,"date_created":"2025-12-16T12:21:49Z","file_name":"2025_ICML_Pervez.pdf","success":1}],"OA_place":"publisher","status":"public","alternative_title":["PMLR"],"publication":"42nd International Conference on Machine Learning","quality_controlled":"1","external_id":{"arxiv":["2502.18377"]},"ddc":["000"],"_id":"20817","article_processing_charge":"No","OA_type":"gold","acknowledgement":"AP. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.\r\nFL. This research was funded in whole or in part by the Austrian Science Fund (FWF) 10.55776/COE12. For open access purposes, the author has applied a CC BY public\r\ncopyright license to any author accepted manuscript version arising from this submission.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_created":"2025-12-14T23:02:04Z","day":"01","publication_status":"published","intvolume":"       267","corr_author":"1","project":[{"name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"has_accepted_license":"1","file_date_updated":"2025-12-16T12:21:49Z","ec_funded":1,"date_published":"2025-05-01T00:00:00Z","volume":267,"language":[{"iso":"eng"}],"scopus_import":"1","month":"05","author":[{"id":"fca6d90c-d47f-11ee-bc87-93ff51604981","full_name":"Pervez, Adeel A","last_name":"Pervez","first_name":"Adeel A"},{"last_name":"Gavves","first_name":"Efstratios","full_name":"Gavves, Efstratios"},{"full_name":"Locatello, Francesco","id":"26cfd52f-2483-11ee-8040-88983bcc06d4","orcid":"0000-0002-4850-0683","first_name":"Francesco","last_name":"Locatello"}],"conference":{"name":"ICML: International Conference on Machine Learning","start_date":"2025-07-13","location":"Vancouver, Canada","end_date":"2025-07-19"},"oa_version":"Published Version","citation":{"chicago":"Pervez, Adeel A, Efstratios Gavves, and Francesco Locatello. “Mechanistic PDE Networks for Discovery of Governing Equations.” In <i>42nd International Conference on Machine Learning</i>, 267:48962–73. ML Research Press, 2025.","ista":"Pervez AA, Gavves E, Locatello F. 2025. Mechanistic PDE networks for discovery of governing equations. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 48962–48973.","mla":"Pervez, Adeel A., et al. “Mechanistic PDE Networks for Discovery of Governing Equations.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 48962–73.","ieee":"A. A. Pervez, E. Gavves, and F. Locatello, “Mechanistic PDE networks for discovery of governing equations,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 48962–48973.","short":"A.A. Pervez, E. Gavves, F. Locatello, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 48962–48973.","apa":"Pervez, A. A., Gavves, E., &#38; Locatello, F. (2025). Mechanistic PDE networks for discovery of governing equations. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 48962–48973). Vancouver, Canada: ML Research Press.","ama":"Pervez AA, Gavves E, Locatello F. Mechanistic PDE networks for discovery of governing equations. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:48962-48973."},"abstract":[{"text":"We present Mechanistic PDE Networks -- a model for discovery of governing partial differential equations from data. Mechanistic PDE Networks represent spatiotemporal data as space-time dependent linear partial differential equations in neural network hidden representations. The represented PDEs are then solved and decoded for specific tasks. The learned PDE representations naturally express the spatiotemporal dynamics in data in neural network hidden space, enabling increased modeling power. Solving the PDE representations in a compute and memory-efficient way, however, is a significant challenge. We develop a native, GPU-capable, parallel, sparse and differentiable multigrid solver specialized for linear partial differential equations that acts as a module in Mechanistic PDE Networks. Leveraging the PDE solver we propose a discovery architecture that can discovers nonlinear PDEs in complex settings, while being robust to noise. We validate PDE discovery on a number of PDEs including reaction-diffusion and Navier-Stokes equations.","lang":"eng"}],"arxiv":1,"type":"conference","publication_identifier":{"eissn":["2640-3498"]},"date_updated":"2025-12-16T12:24:55Z","year":"2025","title":"Mechanistic PDE networks for discovery of governing equations","related_material":{"link":[{"relation":"software","url":"https://github.com/ alpz/mech-nn-discovery-pde"}]}},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2025-12-14T23:02:05Z","day":"01","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"acknowledged_ssus":[{"_id":"ScienComp"}],"intvolume":"       267","publication_status":"published","file":[{"access_level":"open_access","content_type":"application/pdf","date_updated":"2025-12-16T12:38:29Z","creator":"dernst","file_id":"20829","relation":"main_file","success":1,"file_name":"2025_ICML_Scott.pdf","date_created":"2025-12-16T12:38:29Z","file_size":746612,"checksum":"815b32b463023ca21e569c2158745c15"}],"oa":1,"publisher":"ML Research Press","department":[{"_id":"ChLa"},{"_id":"MoHe"}],"page":"53757-53790","publication":"42nd International Conference on Machine Learning","status":"public","alternative_title":["PMLR"],"OA_place":"publisher","ddc":["000"],"quality_controlled":"1","external_id":{"arxiv":["2506.05408"]},"acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF) [10.55776/COE12] and supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).\r\n","_id":"20819","article_processing_charge":"No","OA_type":"gold","oa_version":"Published Version","conference":{"end_date":"2025-07-19","start_date":"2025-07-13","location":"Vancouver, Canada","name":"ICML: International Conference on Machine Learning"},"author":[{"id":"e499926b-f6e0-11ea-865d-9c63db0031e8","full_name":"Scott, Jonathan A","last_name":"Scott","first_name":"Jonathan A"},{"id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","full_name":"Lampert, Christoph","last_name":"Lampert","orcid":"0000-0001-8622-7887","first_name":"Christoph"},{"last_name":"Saulpic","first_name":"David","id":"f8e48cf0-b0ff-11ed-b0e9-b4c35598f964","full_name":"Saulpic, David"}],"abstract":[{"lang":"eng","text":"Clustering is a cornerstone of data analysis that is particularly suited to identifying coherent subgroups or substructures in unlabeled data, as are generated continuously in large amounts these days. However, in many cases traditional clustering methods are not applicable, because data are increasingly being produced and stored in a distributed way, e.g. on edge devices, and privacy concerns prevent it from being transferred to a central server. To address this challenge, we present FedDP-KMeans, a new algorithm for \r\n-means clustering that is fully-federated as well as differentially private. Our approach leverages (potentially small and out-of-distribution) server-side data to overcome the primary challenge of differentially private clustering methods: the need for a good initialization. Combining our initialization with a simple federated DP-Lloyds algorithm we obtain an algorithm that achieves excellent results on synthetic and real-world benchmark tasks. We also provide a theoretical analysis of our method that provides bounds on the convergence speed and cluster identification success."}],"citation":{"ieee":"J. A. Scott, C. Lampert, and D. Saulpic, “Differentially private federated k-means clustering with server-side data,” in <i>42nd International Conference on Machine Learning</i>, Vancouver, Canada, 2025, vol. 267, pp. 53757–53790.","mla":"Scott, Jonathan A., et al. “Differentially Private Federated K-Means Clustering with Server-Side Data.” <i>42nd International Conference on Machine Learning</i>, vol. 267, ML Research Press, 2025, pp. 53757–90.","chicago":"Scott, Jonathan A, Christoph Lampert, and David Saulpic. “Differentially Private Federated K-Means Clustering with Server-Side Data.” In <i>42nd International Conference on Machine Learning</i>, 267:53757–90. ML Research Press, 2025.","ista":"Scott JA, Lampert C, Saulpic D. 2025. Differentially private federated k-means clustering with server-side data. 42nd International Conference on Machine Learning. ICML: International Conference on Machine Learning, PMLR, vol. 267, 53757–53790.","short":"J.A. Scott, C. Lampert, D. Saulpic, in:, 42nd International Conference on Machine Learning, ML Research Press, 2025, pp. 53757–53790.","apa":"Scott, J. A., Lampert, C., &#38; Saulpic, D. (2025). Differentially private federated k-means clustering with server-side data. In <i>42nd International Conference on Machine Learning</i> (Vol. 267, pp. 53757–53790). Vancouver, Canada: ML Research Press.","ama":"Scott JA, Lampert C, Saulpic D. Differentially private federated k-means clustering with server-side data. In: <i>42nd International Conference on Machine Learning</i>. Vol 267. ML Research Press; 2025:53757-53790."},"date_updated":"2026-04-07T11:46:11Z","publication_identifier":{"eissn":["2640-3498"]},"arxiv":1,"type":"conference","related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"21198"}]},"title":"Differentially private federated k-means clustering with server-side data","year":"2025","volume":267,"date_published":"2025-05-01T00:00:00Z","file_date_updated":"2025-12-16T12:38:29Z","has_accepted_license":"1","corr_author":"1","language":[{"iso":"eng"}],"scopus_import":"1","month":"05"},{"intvolume":"       209","publication_status":"published","keyword":["minimum 0-extension problem","metric labeling problem","discrete metric spaces","metric extensions","computational complexity","valued constraint satisfaction problems","discrete convex analysis","L-convex functions"],"date_created":"2021-09-27T10:48:23Z","day":"01","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank the anonymous reviewers for their careful reading of our manuscript and their many insightful comments and suggestions. Open access funding provided by Institute of Science and Technology (IST Austria).","isi":1,"_id":"10045","OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["001176563300001"],"arxiv":["2109.10203"]},"quality_controlled":"1","ddc":["004"],"status":"public","publication":"Mathematical Programming","OA_place":"publisher","file":[{"access_level":"open_access","content_type":"application/pdf","date_updated":"2025-04-16T09:36:08Z","file_id":"19578","relation":"main_file","creator":"dernst","success":1,"file_name":"2025_MathProgramming_Dvorak.pdf","checksum":"25d9bd490719b45eca84f4d93a06c69f","file_size":839510,"date_created":"2025-04-16T09:36:08Z"}],"oa":1,"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"page":"279-322","publisher":"Springer Nature","title":"Generalized minimum 0-extension problem and discrete convexity","year":"2025","date_updated":"2025-05-19T13:52:10Z","type":"journal_article","arxiv":1,"publication_identifier":{"issn":["0025-5610"],"eissn":["1436-4646"]},"citation":{"apa":"Dvorak, M., &#38; Kolmogorov, V. (2025). Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>","ama":"Dvorak M, Kolmogorov V. Generalized minimum 0-extension problem and discrete convexity. <i>Mathematical Programming</i>. 2025;209:279-322. doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>","ista":"Dvorak M, Kolmogorov V. 2025. Generalized minimum 0-extension problem and discrete convexity. Mathematical Programming. 209, 279–322.","chicago":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10107-024-02064-5\">https://doi.org/10.1007/s10107-024-02064-5</a>.","mla":"Dvorak, Martin, and Vladimir Kolmogorov. “Generalized Minimum 0-Extension Problem and Discrete Convexity.” <i>Mathematical Programming</i>, vol. 209, Springer Nature, 2025, pp. 279–322, doi:<a href=\"https://doi.org/10.1007/s10107-024-02064-5\">10.1007/s10107-024-02064-5</a>.","ieee":"M. Dvorak and V. Kolmogorov, “Generalized minimum 0-extension problem and discrete convexity,” <i>Mathematical Programming</i>, vol. 209. Springer Nature, pp. 279–322, 2025.","short":"M. Dvorak, V. Kolmogorov, Mathematical Programming 209 (2025) 279–322."},"abstract":[{"text":"Given a fixed finite metric space (V,μ), the {\\em minimum 0-extension problem}, denoted as 0-Ext[μ], is equivalent to the following optimization problem: minimize function of the form minx∈Vn∑ifi(xi)+∑ijcijμ(xi,xj) where cij,cvi are given nonnegative costs and fi:V→R are functions given by fi(xi)=∑v∈Vcviμ(xi,v). The computational complexity of 0-Ext[μ] has been recently established by Karzanov and by Hirai: if metric μ is {\\em orientable modular} then 0-Ext[μ] can be solved in polynomial time, otherwise 0-Ext[μ] is NP-hard. To prove the tractability part, Hirai developed a theory of discrete convex functions on orientable modular graphs generalizing several known classes of functions in discrete convex analysis, such as L♮-convex functions. We consider a more general version of the problem in which unary functions fi(xi) can additionally have terms of the form cuv;iμ(xi,{u,v}) for {u,v}∈F, where set F⊆(V2) is fixed. We extend the complexity classification above by providing an explicit condition on (μ,F) for the problem to be tractable. In order to prove the tractability part, we generalize Hirai's theory and define a larger class of discrete convex functions. It covers, in particular, another well-known class of functions, namely submodular functions on an integer lattice. Finally, we improve the complexity of Hirai's algorithm for solving 0-Ext on orientable modular graphs.\r\n","lang":"eng"}],"oa_version":"Published Version","author":[{"orcid":"0000-0001-5293-214X","first_name":"Martin","last_name":"Dvorak","full_name":"Dvorak, Martin","id":"40ED02A8-C8B4-11E9-A9C0-453BE6697425"},{"full_name":"Kolmogorov, Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov"}],"month":"01","doi":"10.1007/s10107-024-02064-5","scopus_import":"1","language":[{"iso":"eng"}],"article_type":"original","date_published":"2025-01-01T00:00:00Z","volume":209,"corr_author":"1","file_date_updated":"2025-04-16T09:36:08Z","has_accepted_license":"1"},{"abstract":[{"lang":"eng","text":"Biological memory is known to be flexible—memory formation and recall depend on factors such as the behavioral context of the organism. However, this property is often ignored in associative memory models, leaving it unclear how memories can be organized and recalled when subject to contextual control. Because of the lack of a rigorous analytical framework, it is also unknown how contextual control affects memory stability, storage capacity, and information content. Here, we bring the dynamic nature of memory to the fore by introducing a novel model of associative memory, which we refer to as the context-modular memory network. In our model, stored memory patterns are associated to one of several background network states, or contexts. Memories are accessible when their corresponding context is active, and are otherwise inaccessible. Context modulates the effective network connectivity by imposing a specific\r\nconfiguration of neuronal and synaptic gating—gated neurons (synapses) have their activity (weights) momentarily silenced, thereby reducing interference from memories belonging to other contexts. Memory patterns are randomly and independently chosen, while neuronal and synaptic gates may be selected randomly or optimized through a process of contextual synaptic refinement. Through analytic and numerical results, we show that context-modular memory networks can exhibit both improved memory capacity and differential control of memory stability with random gating (especially for neuronal gating). For contextual synaptic refinement, we devise a method in which synapses are gated off for a given context if they destabilize the memory patterns in that context, drastically improving memory capacity and enabling even more precise control over memory stability. Notably, synaptic refinement allows for patterns to be\r\naccessible in multiple contexts, stabilizing memory patterns even for weight matrices that alone do not contain any information about the memory patterns, such as Gaussian random matrices. Overall, our model integrates recent ideas about context-dependent memory organization with classic associative memory models and proposes a rigorous theory which can act as a framework for future work. Furthermore, our work carries important implications for the understanding of biological memory storage and recall in the brain, such as highlighting an intriguing trade-off between memory capacity and accessibility."}],"article_number":"011057","citation":{"ama":"Podlaski WF, Agnes EJ, Vogels TP. High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. <i>Physical Review X</i>. 2025;15. doi:<a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">10.1103/PhysRevX.15.011057</a>","apa":"Podlaski, W. F., Agnes, E. J., &#38; Vogels, T. P. (2025). High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">https://doi.org/10.1103/PhysRevX.15.011057</a>","short":"W.F. Podlaski, E.J. Agnes, T.P. Vogels, Physical Review X 15 (2025).","chicago":"Podlaski, William F., Everton J. Agnes, and Tim P Vogels. “High Capacity and Dynamic Accessibility in Associative Memory Networks with Context-Dependent Neuronal and Synaptic Gating.” <i>Physical Review X</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">https://doi.org/10.1103/PhysRevX.15.011057</a>.","ista":"Podlaski WF, Agnes EJ, Vogels TP. 2025. High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. Physical Review X. 15, 011057.","ieee":"W. F. Podlaski, E. J. Agnes, and T. P. Vogels, “High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating,” <i>Physical Review X</i>, vol. 15. American Physical Society, 2025.","mla":"Podlaski, William F., et al. “High Capacity and Dynamic Accessibility in Associative Memory Networks with Context-Dependent Neuronal and Synaptic Gating.” <i>Physical Review X</i>, vol. 15, 011057, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">10.1103/PhysRevX.15.011057</a>."},"oa_version":"Published Version","author":[{"full_name":"Podlaski, William F.","first_name":"William F.","orcid":"0000-0001-6619-7502","last_name":"Podlaski"},{"full_name":"Agnes, Everton J.","first_name":"Everton J.","orcid":"0000-0001-7184-7311","last_name":"Agnes"},{"full_name":"Vogels, Tim P","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","orcid":"0000-0003-3295-6181","first_name":"Tim P","last_name":"Vogels"}],"related_material":{"link":[{"relation":"software","url":"https://github.com/wpodlaski/contextual-memory-nets"}]},"title":"High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating","year":"2025","date_updated":"2026-05-06T12:44:27Z","publication_identifier":{"eissn":["2160-3308"]},"type":"journal_article","language":[{"iso":"eng"}],"APC_amount":"4910,08 EUR","article_type":"original","volume":15,"date_published":"2025-03-13T00:00:00Z","has_accepted_license":"1","file_date_updated":"2025-03-20T12:47:17Z","project":[{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"},{"_id":"c084a126-5a5b-11eb-8a69-d75314a70a87","grant_number":"214316/Z/18/Z","name":"What’s in a memory? Spatiotemporal dynamics in strongly coupled recurrent neuronal networks."}],"corr_author":"1","month":"03","doi":"10.1103/PhysRevX.15.011057","scopus_import":"1","date_created":"2020-07-16T12:24:28Z","day":"13","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"        15","publication_status":"published","locked":"1","publication":"Physical Review X","status":"public","OA_place":"publisher","file":[{"success":1,"file_name":"2025_PhysReviewX_Podlaski.pdf","checksum":"1f27ee469ab51a3e1ce1e2df0022e81d","file_size":1373704,"date_created":"2025-03-20T12:47:17Z","access_level":"open_access","date_updated":"2025-03-20T12:47:17Z","content_type":"application/pdf","relation":"main_file","file_id":"19432","creator":"dernst"}],"oa":1,"publisher":"American Physical Society","department":[{"_id":"TiVo"}],"acknowledgement":"We thank Helen Barron, Vezha Boboeva, Adam Packer, João Sacramento, Andrew Saxe, Misha Tsodyks, and Friedemann Zenke for helpful comments at various stages of this work, and Rubem Erichsen, Jr. for carefully reading the manuscript and valuable comments. This work was\r\nsupported by a Sir Henry Dale Fellowship by the Wellcome Trust and the Royal Society [No. WT100000 (W. F. P., E. J. A., and T. P. V.)], a Wellcome Trust Senior Research Fellowship [No. 214316/Z/18/Z (E. J. A. and T. P. V.)], and a Research Project Grant by the Leverhulme Trust\r\n[No. RPG-2016-446 (E. J. A.)]. ","OA_type":"gold","_id":"8125","article_processing_charge":"Yes","isi":1,"ddc":["530"],"external_id":{"isi":["001451378900002"]},"quality_controlled":"1"},{"department":[{"_id":"SiHi"}],"publisher":"Springer Nature","file":[{"success":1,"checksum":"f59748cb67232cfb210035d9aef60836","date_created":"2025-07-07T09:52:46Z","file_size":17018106,"file_name":"2025_NatureComm_Gao.pdf","content_type":"application/pdf","date_updated":"2025-07-07T09:52:46Z","access_level":"open_access","file_id":"19971","relation":"main_file","creator":"dernst"}],"oa":1,"OA_place":"publisher","status":"public","publication":"Nature Communications","external_id":{"isi":["001523450500035"]},"quality_controlled":"1","ddc":["570"],"isi":1,"article_processing_charge":"Yes","_id":"8616","OA_type":"gold","acknowledgement":"The project was initiated in the Jan lab at UCSF. We thank Lily Jan and Yuh-Nung Jan’s generous support. We thank Liqun Luo’s lab for providing MADM-7 mice and Rolf A Brekken for VEGF-antibodies.  Drs. Yuanquan Song (UPenn), Zhaozhu Hu (JHU), Ji Hu (ShanghaiTech), Yang Xiang (U. Mass), Hao Wang (Zhejiang U.) and Ruikang Wang (U. Washington) for critical input, colleagues at Children’s Research Institute, Departments of Neuroscience, Neurology and Neurotherapeutics, Pediatrics from UT Southwestern, and colleagues from the Jan lab for discussion. Dr. Bridget Samuels, Sean Morrison (UT Southwestern), and Nannan Lu (Zhejiang U.) for critical reading. We acknowledge the assistance of the CIBR Imaging core. We also thank UT Southwestern Live Cell Imaging Facility, a Shared Resource of the Harold C. Simmons Cancer Center, supported in part by an NCI Cancer Center Support Grant, P30 CA142543K. This work is supported by CIBR funds and the American Heart Association AWRP Summer 2016 Innovative Research Grant (17IRG33410377) to W-P.G.; National Natural Science Foundation of China (No.81370031) to Z.Z.;National Key Research and Development Program of China (2016YFE0125400)to F.H.;National Natural Science Foundations of China (No. 81473202) to Y.L.; National Natural Science Foundation of China (No.31600839) and Shenzhen Science and Technology Research Program (JCYJ20170818163320865) to B.P.; National Natural Science Foundation of China (No. 31800864) and Westlake University start-up funds to J-M. J. NIH R01NS088627 to W.L.J.; NIH: R01 AG020670 and RF1AG054111 to H.Z.; R01 NS088555 to A.M.S., and European Research Council No.725780 to S.H.;W-P.G. was a recipient of Bugher-American Heart Association Dan Adams Thinking Outside the Box Award.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"date_created":"2020-10-06T08:58:59Z","day":"01","publication_status":"published","intvolume":"        16","DOAJ_listed":"1","project":[{"call_identifier":"H2020","grant_number":"725780","_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}],"file_date_updated":"2025-07-07T09:52:46Z","has_accepted_license":"1","ec_funded":1,"volume":16,"date_published":"2025-07-01T00:00:00Z","article_type":"original","language":[{"iso":"eng"}],"scopus_import":"1","month":"07","doi":"10.1038/s41467-025-60308-0","author":[{"last_name":"Gao","first_name":"Xiaofei","full_name":"Gao, Xiaofei"},{"first_name":"Jun-Liszt","last_name":"Li","full_name":"Li, Jun-Liszt"},{"full_name":"Chen, Xingjun","first_name":"Xingjun","last_name":"Chen"},{"full_name":"Ci, Bo","first_name":"Bo","last_name":"Ci"},{"full_name":"Chen, Fei","last_name":"Chen","first_name":"Fei"},{"first_name":"Nannan","last_name":"Lu","full_name":"Lu, Nannan"},{"first_name":"Bo","last_name":"Shen","full_name":"Shen, Bo"},{"full_name":"Zheng, Lijun","first_name":"Lijun","last_name":"Zheng"},{"last_name":"Jia","first_name":"Jie-Min","full_name":"Jia, Jie-Min"},{"first_name":"Yating","last_name":"Yi","full_name":"Yi, Yating"},{"first_name":"Shiwen","last_name":"Zhang","full_name":"Zhang, Shiwen"},{"full_name":"Shi, Ying-Chao","first_name":"Ying-Chao","last_name":"Shi"},{"full_name":"Shi, Kaibin","last_name":"Shi","first_name":"Kaibin"},{"last_name":"Propson","first_name":"Nicholas E","full_name":"Propson, Nicholas E"},{"full_name":"Huang, Yubin","last_name":"Huang","first_name":"Yubin"},{"full_name":"Poinsatte, Katherine","last_name":"Poinsatte","first_name":"Katherine"},{"full_name":"Zhang, Zhaohuan","first_name":"Zhaohuan","last_name":"Zhang"},{"last_name":"Yue","first_name":"Yuanlei","full_name":"Yue, Yuanlei"},{"first_name":"Dale B","last_name":"Bosco","full_name":"Bosco, Dale B"},{"full_name":"Lu, Ying-mei","last_name":"Lu","first_name":"Ying-mei"},{"full_name":"Yang, Shi-bing","first_name":"Shi-bing","last_name":"Yang"},{"full_name":"Adams, Ralf H.","first_name":"Ralf H.","last_name":"Adams"},{"full_name":"Lindner, Volkhard","first_name":"Volkhard","last_name":"Lindner"},{"full_name":"Huang, Fen","first_name":"Fen","last_name":"Huang"},{"full_name":"Wu, Long-Jun","last_name":"Wu","first_name":"Long-Jun"},{"full_name":"Zheng, Hui","last_name":"Zheng","first_name":"Hui"},{"full_name":"Han, Feng","first_name":"Feng","last_name":"Han"},{"full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2279-1061","first_name":"Simon","last_name":"Hippenmeyer"},{"full_name":"Stowe, Ann M.","last_name":"Stowe","first_name":"Ann M."},{"first_name":"Bo","last_name":"Peng","full_name":"Peng, Bo"},{"first_name":"Marta","last_name":"Margeta","full_name":"Margeta, Marta"},{"last_name":"Wang","first_name":"Xiaoqun","full_name":"Wang, Xiaoqun"},{"first_name":"Qiang","last_name":"Liu","full_name":"Liu, Qiang"},{"first_name":"Jakob","last_name":"Körbelin","full_name":"Körbelin, Jakob"},{"last_name":"Trepel","first_name":"Martin","full_name":"Trepel, Martin"},{"full_name":"Lu, Hui","last_name":"Lu","first_name":"Hui"},{"full_name":"Zhou, Bo O.","first_name":"Bo O.","last_name":"Zhou"},{"full_name":"Zhao, Hu","first_name":"Hu","last_name":"Zhao"},{"last_name":"Su","first_name":"Wenzhi","full_name":"Su, Wenzhi"},{"first_name":"Robert M.","last_name":"Bachoo","full_name":"Bachoo, Robert M."},{"full_name":"Ge, Woo-ping","last_name":"Ge","first_name":"Woo-ping"}],"oa_version":"Published Version","article_number":"5840","citation":{"mla":"Gao, Xiaofei, et al. “Reduction of Neuronal Activity Mediated by Blood-Vessel Regression in the Brain.” <i>Nature Communications</i>, vol. 16, 5840, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-60308-0\">10.1038/s41467-025-60308-0</a>.","ieee":"X. Gao <i>et al.</i>, “Reduction of neuronal activity mediated by blood-vessel regression in the brain,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","chicago":"Gao, Xiaofei, Jun-Liszt Li, Xingjun Chen, Bo Ci, Fei Chen, Nannan Lu, Bo Shen, et al. “Reduction of Neuronal Activity Mediated by Blood-Vessel Regression in the Brain.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-60308-0\">https://doi.org/10.1038/s41467-025-60308-0</a>.","ista":"Gao X, Li J-L, Chen X, Ci B, Chen F, Lu N, Shen B, Zheng L, Jia J-M, Yi Y, Zhang S, Shi Y-C, Shi K, Propson NE, Huang Y, Poinsatte K, Zhang Z, Yue Y, Bosco DB, Lu Y, Yang S, Adams RH, Lindner V, Huang F, Wu L-J, Zheng H, Han F, Hippenmeyer S, Stowe AM, Peng B, Margeta M, Wang X, Liu Q, Körbelin J, Trepel M, Lu H, Zhou BO, Zhao H, Su W, Bachoo RM, Ge W. 2025. Reduction of neuronal activity mediated by blood-vessel regression in the brain. Nature Communications. 16, 5840.","short":"X. Gao, J.-L. Li, X. Chen, B. Ci, F. Chen, N. Lu, B. Shen, L. Zheng, J.-M. Jia, Y. Yi, S. Zhang, Y.-C. Shi, K. Shi, N.E. Propson, Y. Huang, K. Poinsatte, Z. Zhang, Y. Yue, D.B. Bosco, Y. Lu, S. Yang, R.H. Adams, V. Lindner, F. Huang, L.-J. Wu, H. Zheng, F. Han, S. Hippenmeyer, A.M. Stowe, B. Peng, M. Margeta, X. Wang, Q. Liu, J. Körbelin, M. Trepel, H. Lu, B.O. Zhou, H. Zhao, W. Su, R.M. Bachoo, W. Ge, Nature Communications 16 (2025).","apa":"Gao, X., Li, J.-L., Chen, X., Ci, B., Chen, F., Lu, N., … Ge, W. (2025). Reduction of neuronal activity mediated by blood-vessel regression in the brain. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-60308-0\">https://doi.org/10.1038/s41467-025-60308-0</a>","ama":"Gao X, Li J-L, Chen X, et al. Reduction of neuronal activity mediated by blood-vessel regression in the brain. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-60308-0\">10.1038/s41467-025-60308-0</a>"},"abstract":[{"lang":"eng","text":"The brain vasculature supplies neurons with glucose and oxygen, but little is known about how vascular plasticity contributes to brain function. Using longitudinal in vivo imaging, we report that a substantial proportion of blood vessels in the adult mouse brain sporadically occlude and regress. Their regression proceeds through sequential stages of blood-flow occlusion, endothelial cell collapse, relocation or loss of pericytes, and retraction of glial endfeet. Regressing vessels are found to be widespread in mouse, monkey and human brains. We further reveal that blood vessel regression cause a reduction of neuronal activity due to a dysfunction in mitochondrial metabolism and glutamate production. Our results elucidate the mechanism of vessel regression and its role in neuronal function in the adult brain."}],"type":"journal_article","publication_identifier":{"eissn":["2041-1723"]},"date_updated":"2025-09-04T07:08:37Z","year":"2025","title":"Reduction of neuronal activity mediated by blood-vessel regression in the brain"},{"date_updated":"2026-04-07T13:01:40Z","publication_identifier":{"issn":["1424-0637"]},"type":"journal_article","related_material":{"record":[{"id":"18135","relation":"dissertation_contains","status":"public"}]},"title":"Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion","year":"2025","oa_version":"Published Version","author":[{"last_name":"Lauritsen","orcid":"0000-0003-4476-2288","first_name":"Asbjørn Bækgaard","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","full_name":"Lauritsen, Asbjørn Bækgaard"}],"abstract":[{"lang":"eng","text":"We prove an upper bound on the energy density of the dilute spin-\\(\\frac {1}{2}\\) Fermi gas capturing the leading correction to the kinetic energy\\(8\\pi a\\rho _\\uparrow\\rho _\\downarrow\\) with an error of size smaller than\\(a\\rho^{2}(a^ 3\\rho)^{1/3-\\varepsilon}\\) for any\\(\\varepsilon> 0\\), where a denotes the scattering length of the interaction. The result is valid for a large class of interactions including interactions with a hard core. A central ingredient in the proof is a rigorous version of a fermionic cluster expansion adapted from the formal expansion of Gaudin et al. (Nucl Phys A 176(2):237–260, 1971. https://doi.org/10.1016/0375-9474(71)90267-3)."}],"citation":{"ama":"Lauritsen AB. Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. <i>Annales Henri Poincare</i>. 2025;26:203-243. doi:<a href=\"https://doi.org/10.1007/s00023-024-01450-1\">10.1007/s00023-024-01450-1</a>","apa":"Lauritsen, A. B. (2025). Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. <i>Annales Henri Poincare</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00023-024-01450-1\">https://doi.org/10.1007/s00023-024-01450-1</a>","short":"A.B. Lauritsen, Annales Henri Poincare 26 (2025) 203–243.","mla":"Lauritsen, Asbjørn Bækgaard. “Almost Optimal Upper Bound for the Ground State Energy of a Dilute Fermi Gas via Cluster Expansion.” <i>Annales Henri Poincare</i>, vol. 26, Springer Nature, 2025, pp. 203–43, doi:<a href=\"https://doi.org/10.1007/s00023-024-01450-1\">10.1007/s00023-024-01450-1</a>.","ieee":"A. B. Lauritsen, “Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion,” <i>Annales Henri Poincare</i>, vol. 26. Springer Nature, pp. 203–243, 2025.","chicago":"Lauritsen, Asbjørn Bækgaard. “Almost Optimal Upper Bound for the Ground State Energy of a Dilute Fermi Gas via Cluster Expansion.” <i>Annales Henri Poincare</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00023-024-01450-1\">https://doi.org/10.1007/s00023-024-01450-1</a>.","ista":"Lauritsen AB. 2025. Almost optimal upper bound for the ground state energy of a dilute Fermi gas via cluster expansion. Annales Henri Poincare. 26, 203–243."},"scopus_import":"1","month":"01","doi":"10.1007/s00023-024-01450-1","volume":26,"date_published":"2025-01-01T00:00:00Z","PlanS_conform":"1","has_accepted_license":"1","file_date_updated":"2025-08-05T11:42:27Z","project":[{"name":"Mathematical Challenges in BCS Theory of Superconductivity","_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b","grant_number":"I06427"}],"corr_author":"1","language":[{"iso":"eng"}],"article_type":"original","intvolume":"        26","publication_status":"published","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","pmid":1,"day":"01","date_created":"2024-07-14T22:01:12Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"ddc":["510"],"quality_controlled":"1","external_id":{"pmid":["39926012"],"isi":["001261197700002"]},"acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).\r\nWe thank Alessandro Giuliani and Robert Seiringer for helpful discussions and Robert Seiringer for his comments on the manuscript. Financial support by the Austrian Science Fund (FWF) through Grant https://doi.org/10.55776/I6427 (as part of the SFB/TRR 352) is gratefully acknowledged.","OA_type":"hybrid","_id":"17240","article_processing_charge":"Yes (via OA deal)","isi":1,"oa":1,"file":[{"access_level":"open_access","date_updated":"2025-08-05T11:42:27Z","content_type":"application/pdf","file_id":"20125","relation":"main_file","creator":"dernst","success":1,"file_name":"2025_AnnalesHenriPoincare_Lauritsen.pdf","checksum":"01b6572f55f721e97498522c85072ed2","date_created":"2025-08-05T11:42:27Z","file_size":797241}],"publisher":"Springer Nature","page":"203-243","department":[{"_id":"RoSe"}],"publication":"Annales Henri Poincare","status":"public","OA_place":"publisher"},{"abstract":[{"text":"Voltage-gated CaV2.1 (P/Q-type) Ca2+ channels play a crucial role in regulating neurotransmitter release, thus contributing to synaptic plasticity and to processes such as learning and memory. Despite their recognized importance in neural function, there is limited information on their potential involvement in neurodegenerative conditions such as Alzheimer's disease (AD). Here, we aimed to explore the impact of AD pathology on the density and nanoscale compartmentalization of CaV2.1 channels in the hippocampus in association with GABAB receptors. Histoblotting experiments showed that the density of CaV2.1 channel was significantly reduced in the hippocampus of APP/PS1 mice in a laminar-dependent manner. CaV2.1 channel was enriched in the active zone of the axon terminals and was present at a very low density over the surface of dendritic tree of the CA1 pyramidal cells, as shown by quantitative SDS-digested freeze-fracture replica labelling (SDS-FRL). In APP/PS1 mice, the density of CaV2.1 channel in the active zone was significantly reduced in the strata radiatum and lacunosum-moleculare, while it remained unaltered in the stratum oriens. The decline in Cav2.1 channel density was found to be associated with a corresponding impairment in the GABAergic synaptic function, as evidenced by electrophysiological experiments carried out in the hippocampus of APP/PS1 mice. Remarkably, double SDS-FRL showed a co-clustering of CaV2.1 channel and GABAB1 receptor in nanodomains (~40–50 nm) in wild type mice, while in APP/PS1 mice this nanoarchitecture was absent. Together, these findings suggest that the AD pathology-induced reduction in CaV2.1 channel density and CaV2.1-GABAB1 de-clustering may play a role in the synaptic transmission alterations shown in the AD hippocampus. Therefore, uncovering these layer-dependent changes in P/Q calcium currents associated with AD pathology can benefit the development of future strategies for AD management.","lang":"eng"}],"citation":{"apa":"Martín‐Belmonte, A., Aguado, C., Alfaro‐Ruiz, R., Kulik, A., de la Ossa, L., Moreno‐Martínez, A. E., … Luján, R. (2025). Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. <i>Brain Pathology</i>. Wiley. <a href=\"https://doi.org/10.1111/bpa.13279\">https://doi.org/10.1111/bpa.13279</a>","ama":"Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, et al. Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. <i>Brain Pathology</i>. 2025;35(2). doi:<a href=\"https://doi.org/10.1111/bpa.13279\">10.1111/bpa.13279</a>","ieee":"A. Martín‐Belmonte <i>et al.</i>, “Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology,” <i>Brain Pathology</i>, vol. 35, no. 2. Wiley, 2025.","mla":"Martín‐Belmonte, Alejandro, et al. “Nanoarchitecture of CaV&#62;2.1 Channels and GABAB Receptors in the Mouse Hippocampus: Impact of APP/PS1 Pathology.” <i>Brain Pathology</i>, vol. 35, no. 2, e13279, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/bpa.13279\">10.1111/bpa.13279</a>.","chicago":"Martín‐Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro‐Ruiz, Akos Kulik, Luis de la Ossa, Ana Esther Moreno‐Martínez, Samuel Alberquilla, et al. “Nanoarchitecture of CaV&#62;2.1 Channels and GABAB Receptors in the Mouse Hippocampus: Impact of APP/PS1 Pathology.” <i>Brain Pathology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/bpa.13279\">https://doi.org/10.1111/bpa.13279</a>.","ista":"Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, Kulik A, de la Ossa L, Moreno‐Martínez AE, Alberquilla S, García‐Carracedo L, Fernández M, Fajardo‐Serrano A, Aso E, Shigemoto R, Martín ED, Fukazawa Y, Ciruela F, Luján R. 2025. Nanoarchitecture of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. Brain Pathology. 35(2), e13279.","short":"A. Martín‐Belmonte, C. Aguado, R. Alfaro‐Ruiz, A. Kulik, L. de la Ossa, A.E. Moreno‐Martínez, S. Alberquilla, L. García‐Carracedo, M. Fernández, A. Fajardo‐Serrano, E. Aso, R. Shigemoto, E.D. Martín, Y. Fukazawa, F. Ciruela, R. Luján, Brain Pathology 35 (2025)."},"article_number":"e13279","author":[{"full_name":"Martín‐Belmonte, Alejandro","first_name":"Alejandro","last_name":"Martín‐Belmonte"},{"full_name":"Aguado, Carolina","last_name":"Aguado","first_name":"Carolina"},{"full_name":"Alfaro‐Ruiz, Rocío","first_name":"Rocío","last_name":"Alfaro‐Ruiz"},{"first_name":"Akos","last_name":"Kulik","full_name":"Kulik, Akos"},{"full_name":"de la Ossa, Luis","first_name":"Luis","last_name":"de la Ossa"},{"full_name":"Moreno‐Martínez, Ana Esther","last_name":"Moreno‐Martínez","first_name":"Ana Esther"},{"full_name":"Alberquilla, Samuel","first_name":"Samuel","last_name":"Alberquilla"},{"last_name":"García‐Carracedo","first_name":"Lucía","full_name":"García‐Carracedo, Lucía"},{"full_name":"Fernández, Miriam","first_name":"Miriam","last_name":"Fernández"},{"last_name":"Fajardo‐Serrano","first_name":"Ana","full_name":"Fajardo‐Serrano, Ana"},{"first_name":"Ester","last_name":"Aso","full_name":"Aso, Ester"},{"last_name":"Shigemoto","first_name":"Ryuichi","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi"},{"full_name":"Martín, Eduardo D.","first_name":"Eduardo D.","last_name":"Martín"},{"first_name":"Yugo","last_name":"Fukazawa","full_name":"Fukazawa, Yugo"},{"first_name":"Francisco","last_name":"Ciruela","full_name":"Ciruela, Francisco"},{"full_name":"Luján, Rafael","first_name":"Rafael","last_name":"Luján"}],"oa_version":"Published Version","year":"2025","title":"Nanoarchitecture of CaV>2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology","publication_identifier":{"eissn":["1750-3639"],"issn":["1015-6305"]},"type":"journal_article","date_updated":"2025-05-19T13:58:12Z","article_type":"original","language":[{"iso":"eng"}],"has_accepted_license":"1","file_date_updated":"2025-04-16T09:56:08Z","volume":35,"date_published":"2025-03-01T00:00:00Z","month":"03","doi":"10.1111/bpa.13279","scopus_import":"1","issue":"2","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"pmid":1,"date_created":"2024-07-22T07:48:20Z","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","DOAJ_listed":"1","intvolume":"        35","OA_place":"publisher","publication":"Brain Pathology","status":"public","publisher":"Wiley","department":[{"_id":"RySh"}],"oa":1,"file":[{"access_level":"open_access","content_type":"application/pdf","date_updated":"2025-04-16T09:56:08Z","relation":"main_file","file_id":"19582","creator":"dernst","success":1,"file_name":"2025_BrainPathology_MartinBelmonte.pdf","checksum":"75a172800ab2e949abb66fba97cf70f0","date_created":"2025-04-16T09:56:08Z","file_size":8767863}],"_id":"17293","article_processing_charge":"Yes","OA_type":"gold","isi":1,"acknowledgement":"Funding sources were Spanish Ministerio de Economía y Competitividad, Junta de Comunidades de Castilla-La Mancha (Spain), Life Science Innovation Center at University of Fukui and German Research Foundation.\r\nGrants RTI2018-095812-B-I00 and PID2021-125875OB-I00 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe” to Rafael Luján. This study was also supported by a grant from Junta de Comunidades de Castilla-La Mancha (SBPLY/17/180501/000229 and SBPLY/21/180501/000064) and Universidad de Castilla-La Mancha (2023-GRIN-34187) to Rafael Luján, and Life Science Innovation Center (Research and Education Program for Life Science) at University of Fukui and JSPS KAKENHI Grant Numbers 16H04662, 17K19446, 18H05120 to Yugo Fukazawa and Margarita Salas fellowship from Ministerio de Universidades and Universidad de Castilla-La Mancha to Alejandro Martín-Belmonte. German Research Foundation (DFG FOR 2143) and BIOSS-2 to Akos Kulik.","ddc":["570"],"quality_controlled":"1","external_id":{"isi":["001250034200001"],"pmid":["38887180"]}},{"author":[{"full_name":"Pan, Yi","first_name":"Yi","last_name":"Pan"},{"first_name":"Mathias","last_name":"Hochgerner","full_name":"Hochgerner, Mathias"},{"id":"d63197a3-c188-11ed-9387-8d33a3f13871","full_name":"Cichon, Malgorzata Anna","last_name":"Cichon","first_name":"Malgorzata Anna"},{"full_name":"Benezeder, Theresa","first_name":"Theresa","last_name":"Benezeder"},{"first_name":"Thomas","last_name":"Bieber","full_name":"Bieber, Thomas"},{"first_name":"Peter","last_name":"Wolf","full_name":"Wolf, Peter"}],"oa_version":"Published Version","abstract":[{"text":"Atopic dermatitis (AD) is the most common chronic inflammatory skin disease worldwide. AD is a highly complex disease with different subtypes. Many elements of AD pathophysiology have been described, but if/how they interact with each other or which mechanisms are important in which patients is still unclear. Langerhans cells (LCs) are antigen-presenting cells (APCs) in the epidermis. Depending on the context, they can act either pro- or anti-inflammatory. Many different studies have investigated LCs in the context of AD and found them to be connected to all major mechanisms of AD pathophysiology. As APCs, LCs recruit other immune cells and shape the immune response, especially adaptive immunity via polarization of T cells. As sentinel cells, LCs are primary sensors of the skin microbiome and are important for the decision of immunity versus tolerance. LCs are also involved with the integrity of the skin barrier by influencing tight junctions. Finally, LCs are important cells in the neuro-immune crosstalk in the skin. In this review, we provide an overview about the many different roles of LCs in AD. Understanding LCs might bring us closer to a more complete understanding of this highly complex disease. Potentially, modulating LCs might offer new options for targeted therapies for AD patients.","lang":"eng"}],"citation":{"short":"Y. Pan, M. Hochgerner, M.A. Cichon, T. Benezeder, T. Bieber, P. Wolf, Journal of the European Academy of Dermatology and Venereology 39 (2025) 278–289.","ieee":"Y. Pan, M. Hochgerner, M. A. Cichon, T. Benezeder, T. Bieber, and P. Wolf, “Langerhans cells: Central players in the pathophysiology of atopic dermatitis,” <i>Journal of the European Academy of Dermatology and Venereology</i>, vol. 39, no. 2. Wiley, pp. 278–289, 2025.","mla":"Pan, Yi, et al. “Langerhans Cells: Central Players in the Pathophysiology of Atopic Dermatitis.” <i>Journal of the European Academy of Dermatology and Venereology</i>, vol. 39, no. 2, Wiley, 2025, pp. 278–89, doi:<a href=\"https://doi.org/10.1111/jdv.20291\">10.1111/jdv.20291</a>.","ista":"Pan Y, Hochgerner M, Cichon MA, Benezeder T, Bieber T, Wolf P. 2025. Langerhans cells: Central players in the pathophysiology of atopic dermatitis. Journal of the European Academy of Dermatology and Venereology. 39(2), 278–289.","chicago":"Pan, Yi, Mathias Hochgerner, Malgorzata Anna Cichon, Theresa Benezeder, Thomas Bieber, and Peter Wolf. “Langerhans Cells: Central Players in the Pathophysiology of Atopic Dermatitis.” <i>Journal of the European Academy of Dermatology and Venereology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/jdv.20291\">https://doi.org/10.1111/jdv.20291</a>.","ama":"Pan Y, Hochgerner M, Cichon MA, Benezeder T, Bieber T, Wolf P. Langerhans cells: Central players in the pathophysiology of atopic dermatitis. <i>Journal of the European Academy of Dermatology and Venereology</i>. 2025;39(2):278-289. doi:<a href=\"https://doi.org/10.1111/jdv.20291\">10.1111/jdv.20291</a>","apa":"Pan, Y., Hochgerner, M., Cichon, M. A., Benezeder, T., Bieber, T., &#38; Wolf, P. (2025). Langerhans cells: Central players in the pathophysiology of atopic dermatitis. <i>Journal of the European Academy of Dermatology and Venereology</i>. Wiley. <a href=\"https://doi.org/10.1111/jdv.20291\">https://doi.org/10.1111/jdv.20291</a>"},"publication_identifier":{"issn":["0926-9959"],"eissn":["1468-3083"]},"type":"journal_article","date_updated":"2025-05-19T13:58:50Z","year":"2025","title":"Langerhans cells: Central players in the pathophysiology of atopic dermatitis","has_accepted_license":"1","file_date_updated":"2025-04-16T09:59:37Z","date_published":"2025-02-01T00:00:00Z","volume":39,"article_type":"original","language":[{"iso":"eng"}],"scopus_import":"1","month":"02","doi":"10.1111/jdv.20291","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"issue":"2","pmid":1,"day":"01","date_created":"2024-08-25T22:01:07Z","publication_status":"published","intvolume":"        39","publisher":"Wiley","department":[{"_id":"MiSi"}],"page":"278-289","oa":1,"file":[{"success":1,"file_name":"2025_JEADV_Pan.pdf","date_created":"2025-04-16T09:59:37Z","file_size":457698,"checksum":"12555ddb3490daf10b8d44e334e7312e","access_level":"open_access","date_updated":"2025-04-16T09:59:37Z","content_type":"application/pdf","creator":"dernst","relation":"main_file","file_id":"19583"}],"OA_place":"publisher","publication":"Journal of the European Academy of Dermatology and Venereology","status":"public","ddc":["570"],"quality_controlled":"1","external_id":{"isi":["001292894900001"],"pmid":["39157943"]},"article_processing_charge":"Yes (in subscription journal)","_id":"17459","OA_type":"hybrid","isi":1,"acknowledgement":"This work was supported by the CK-CARE of the KühneFoundation, Switzerland; the China Scholarship Counciland Shanghai Biocelline Enterprise Co. Ltd, China."},{"year":"2025","title":"Marcus kinetics control singlet and triplet oxygen evolving from superoxide","related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/taming-the-bad-oxygen/"}]},"type":"journal_article","publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"date_updated":"2026-04-28T13:18:33Z","citation":{"apa":"Mondal, S., Nguyen, H. T. K., Hauschild, R., &#38; Freunberger, S. A. (2025). Marcus kinetics control singlet and triplet oxygen evolving from superoxide. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-09587-7\">https://doi.org/10.1038/s41586-025-09587-7</a>","ama":"Mondal S, Nguyen HTK, Hauschild R, Freunberger SA. Marcus kinetics control singlet and triplet oxygen evolving from superoxide. <i>Nature</i>. 2025;646(8085):601–605. doi:<a href=\"https://doi.org/10.1038/s41586-025-09587-7\">10.1038/s41586-025-09587-7</a>","chicago":"Mondal, Soumyadip, Huyen T.K. Nguyen, Robert Hauschild, and Stefan Alexander Freunberger. “Marcus Kinetics Control Singlet and Triplet Oxygen Evolving from Superoxide.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-025-09587-7\">https://doi.org/10.1038/s41586-025-09587-7</a>.","ista":"Mondal S, Nguyen HTK, Hauschild R, Freunberger SA. 2025. Marcus kinetics control singlet and triplet oxygen evolving from superoxide. Nature. 646(8085), 601–605.","mla":"Mondal, Soumyadip, et al. “Marcus Kinetics Control Singlet and Triplet Oxygen Evolving from Superoxide.” <i>Nature</i>, vol. 646, no. 8085, Springer Nature, 2025, pp. 601–605, doi:<a href=\"https://doi.org/10.1038/s41586-025-09587-7\">10.1038/s41586-025-09587-7</a>.","ieee":"S. Mondal, H. T. K. Nguyen, R. Hauschild, and S. A. Freunberger, “Marcus kinetics control singlet and triplet oxygen evolving from superoxide,” <i>Nature</i>, vol. 646, no. 8085. Springer Nature, pp. 601–605, 2025.","short":"S. Mondal, H.T.K. Nguyen, R. Hauschild, S.A. Freunberger, Nature 646 (2025) 601–605."},"abstract":[{"text":"Oxygen redox chemistry is central to life1 and many human-made technologies, such as in energy storage2,3,4. The large energy gain from oxygen redox reactions is often connected with the occurrence of harmful reactive oxygen species3,5,6. Key species are superoxide and the highly reactive singlet oxygen3,4,5,6,7, which may evolve from superoxide. However, the factors determining the formation of singlet oxygen, rather than the relatively unreactive triplet oxygen, are unknown. Here we report that the release of triplet or singlet oxygen is governed by individual Marcus normal and inverted region behaviour. We found that as the driving force for the reaction increases, the initially dominant evolution of triplet oxygen slows down, and singlet oxygen evolution becomes predominant with higher maximum kinetics. This behaviour also applies to the widely observed superoxide disproportionation, in which one superoxide is oxidized by another, in both non-aqueous and aqueous systems, with Lewis and Brønsted acidity controlling the driving forces. Singlet oxygen yields governed by these conditions are relevant, for example, in batteries or cellular organelles in which superoxide forms. Our findings suggest ways to understand and control spin states and kinetics in oxygen redox chemistry, with implications for fields, including life sciences, pure chemistry and energy storage.","lang":"eng"}],"author":[{"id":"d25d21ef-dc8d-11ea-abe3-ec4576307f48","full_name":"Mondal, Soumyadip","last_name":"Mondal","first_name":"Soumyadip"},{"full_name":"Nguyen, Huyen T.K.","first_name":"Huyen T.K.","last_name":"Nguyen"},{"orcid":"0000-0001-9843-3522","first_name":"Robert","last_name":"Hauschild","full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87"},{"id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander"}],"oa_version":"Published Version","doi":"10.1038/s41586-025-09587-7","month":"10","scopus_import":"1","article_type":"original","language":[{"iso":"eng"}],"corr_author":"1","file_date_updated":"2025-10-20T10:26:13Z","project":[{"grant_number":"P37169","_id":"8df062be-16d5-11f0-9cad-f559b6612c7e","name":"Singlet oxygen in non-aqueous oxygen redox chemistry"},{"grant_number":"CZI01","_id":"c08e9ad1-5a5b-11eb-8a69-9d1cf3b07473","name":"Tools for automation and feedback microscopy"}],"has_accepted_license":"1","PlanS_conform":"1","date_published":"2025-10-16T00:00:00Z","volume":646,"publication_status":"published","intvolume":"       646","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"ScienComp"}],"issue":"8085","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"day":"16","date_created":"2024-08-29T10:40:23Z","pmid":1,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","isi":1,"_id":"17468","OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","acknowledgement":"S.A.F. thanks the Institute of Science and Technology Austria (ISTA) for the support. The Scientific Service Units of ISTA supported this research through resources provided by the Imaging and Optics Facility, the Lab Support Facility, the Miba Machine Shop and Scientific Computing. This research was partly funded by the Austrian Science Fund (FWF) (10.55776/P37169 and 10.55776/COE5). For open access purposes, the author has applied for a CC BY public copyright licence to any author-accepted manuscript version arising from this submission. R.H. acknowledges funding through CZI grant DAF2020-225401 (10.37921/120055ratwvi) from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation (10.13039/100014989). H.T.K.N. acknowledges funding by the European Commission Erasmus Mundus Joint Masters programme. We thank M. Sixt and M. Chinon for the discussions about O-redox in life and R. Jethwa for proofreading. Open access funding was provided by ISTA.","external_id":{"pmid":["41044415"],"isi":["001586378900001"]},"quality_controlled":"1","ddc":["540"],"OA_place":"publisher","status":"public","publication":"Nature","department":[{"_id":"StFr"},{"_id":"Bio"}],"page":"601–605","publisher":"Springer Nature","oa":1,"file":[{"checksum":"b507ddd23df0388aa65d04dc9b00fe3d","file_size":3809247,"date_created":"2025-10-20T10:26:13Z","file_name":"2025_Nature_Mondal.pdf","success":1,"file_id":"20500","relation":"main_file","creator":"dernst","date_updated":"2025-10-20T10:26:13Z","content_type":"application/pdf","access_level":"open_access"}]},{"page":"268-276","department":[{"_id":"FlSc"},{"_id":"LeSa"}],"publisher":"Springer Nature","oa":1,"file":[{"file_name":"2025_NatureStrucBio_Obr.pdf","checksum":"c641ad94afb28917b20425db676fc3ee","date_created":"2025-04-23T07:02:33Z","file_size":13724041,"success":1,"relation":"main_file","file_id":"19608","creator":"dernst","access_level":"open_access","date_updated":"2025-04-23T07:02:33Z","content_type":"application/pdf"}],"OA_place":"publisher","status":"public","publication":"Nature Structural & Molecular Biology","external_id":{"oaworkid":["W4402316284"],"pmid":["39242978"],"isi":["001306564000001"]},"quality_controlled":"1","ddc":["570"],"isi":1,"OA_type":"hybrid","_id":"17884","article_processing_charge":"Yes (in subscription journal)","acknowledgement":"This work was funded by the Institute of Science and Technology Austria (ISTA) and the Austrian Science Fund (grant P31445 to F.K.M.S.). Access to high-resolution cryo-ET data acquisition at European Molecular Biology Laboratory (EMBL) Heidelberg was supported through the EMBL cryo-EM platform. We thank V.-V. Hodirnau at ISTA and W. Hagen and F. Weis at EMBL Heidelberg for support in cryo-ET data acquisition. This research was also supported by the scientific service units of ISTA through resources provided by Scientific Computing, the Life Science Facility, and the EM Facility. L.M.M. was supported by National Institutes of Health grants R01 GM151775 and R21 DE032878 and by the University of Minnesota Masonic Cancer Center. D.P. was supported by the DOC doctoral fellowship program of the Austrian Academy of Sciences. R.A.D was supported by the National Institute of Allergy and Infectious Diseases (grant R01AI147890). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. Specifically, we also want to thank A. Schlögl for computational support and J. Hansen and V. Vogt for critical comments on the manuscript. We also thank the other members of the Schur lab for helpful discussions and experimental advice.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"day":"01","date_created":"2024-09-08T10:29:06Z","pmid":1,"acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"oaworkid":1,"publication_status":"published","intvolume":"        32","corr_author":"1","project":[{"grant_number":"P31445","_id":"26736D6A-B435-11E9-9278-68D0E5697425","name":"Structural conservation and diversity in retroviral capsid","call_identifier":"FWF"},{"name":"Structural characterization of spumavirus capsid assemblies to understand conserved Ortervirales assembly mechanisms","_id":"9B9C98E0-BA93-11EA-9121-9846C619BF3A","grant_number":"25762"}],"has_accepted_license":"1","file_date_updated":"2025-04-23T07:02:33Z","volume":32,"date_published":"2025-02-01T00:00:00Z","article_type":"original","APC_amount":"12348 EUR","language":[{"iso":"eng"}],"scopus_import":"1","doi":"10.1038/s41594-024-01390-8","month":"02","author":[{"last_name":"Obr","orcid":"0000-0003-1756-6564","first_name":"Martin","id":"4741CA5A-F248-11E8-B48F-1D18A9856A87","full_name":"Obr, Martin"},{"first_name":"Mathias","last_name":"Percipalle","full_name":"Percipalle, Mathias","id":"4986e21c-eb97-11eb-a6c2-a4ef0b629971"},{"id":"7dbaf460-fa9e-11eb-b0ca-bc7c7ff21ad0","full_name":"Chernikova, Darya","last_name":"Chernikova","first_name":"Darya"},{"first_name":"Huixin","last_name":"Yang","full_name":"Yang, Huixin"},{"full_name":"Thader, Andreas","id":"3A18A7B8-F248-11E8-B48F-1D18A9856A87","first_name":"Andreas","last_name":"Thader"},{"first_name":"Gergely","last_name":"Pinke","full_name":"Pinke, Gergely","id":"4D5303E6-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Porley","first_name":"Dario J","id":"2FD6EA6C-F248-11E8-B48F-1D18A9856A87","full_name":"Porley, Dario J"},{"full_name":"Mansky, Louis M.","first_name":"Louis M.","last_name":"Mansky"},{"full_name":"Dick, Robert A.","last_name":"Dick","first_name":"Robert A."},{"last_name":"Schur","orcid":"0000-0003-4790-8078","first_name":"Florian KM","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","full_name":"Schur, Florian KM"}],"oa_version":"Published Version","citation":{"ama":"Obr M, Percipalle M, Chernikova D, et al. Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice. <i>Nature Structural &#38; Molecular Biology</i>. 2025;32:268-276. doi:<a href=\"https://doi.org/10.1038/s41594-024-01390-8\">10.1038/s41594-024-01390-8</a>","apa":"Obr, M., Percipalle, M., Chernikova, D., Yang, H., Thader, A., Pinke, G., … Schur, F. K. (2025). Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice. <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41594-024-01390-8\">https://doi.org/10.1038/s41594-024-01390-8</a>","short":"M. Obr, M. Percipalle, D. Chernikova, H. Yang, A. Thader, G. Pinke, D. Porley Esteves, L.M. Mansky, R.A. Dick, F.K. Schur, Nature Structural &#38; Molecular Biology 32 (2025) 268–276.","ieee":"M. Obr <i>et al.</i>, “Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice,” <i>Nature Structural &#38; Molecular Biology</i>, vol. 32. Springer Nature, pp. 268–276, 2025.","mla":"Obr, Martin, et al. “Distinct Stabilization of the Human T Cell Leukemia Virus Type 1 Immature Gag Lattice.” <i>Nature Structural &#38; Molecular Biology</i>, vol. 32, Springer Nature, 2025, pp. 268–76, doi:<a href=\"https://doi.org/10.1038/s41594-024-01390-8\">10.1038/s41594-024-01390-8</a>.","chicago":"Obr, Martin, Mathias Percipalle, Darya Chernikova, Huixin Yang, Andreas Thader, Gergely Pinke, Darío Porley Esteves, Louis M. Mansky, Robert A. Dick, and Florian KM Schur. “Distinct Stabilization of the Human T Cell Leukemia Virus Type 1 Immature Gag Lattice.” <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41594-024-01390-8\">https://doi.org/10.1038/s41594-024-01390-8</a>.","ista":"Obr M, Percipalle M, Chernikova D, Yang H, Thader A, Pinke G, Porley Esteves D, Mansky LM, Dick RA, Schur FK. 2025. Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice. Nature Structural &#38; Molecular Biology. 32, 268–276."},"abstract":[{"text":"Human T cell leukemia virus type 1 (HTLV-1) immature particles differ in morphology from other retroviruses, suggesting a distinct way of assembly. Here we report the results of cryo-electron tomography studies of HTLV-1 virus-like particles assembled in vitro, as well as derived from cells. This work shows that HTLV-1 uses a distinct mechanism of Gag–Gag interactions to form the immature viral lattice. Analysis of high-resolution structural information from immature capsid (CA) tubular arrays reveals that the primary stabilizing component in HTLV-1 is the N-terminal domain of CA. Mutagenesis analysis supports this observation. This distinguishes HTLV-1 from other retroviruses, in which the stabilization is provided primarily by the C-terminal domain of CA. These results provide structural details of the quaternary arrangement of Gag for an immature deltaretrovirus and this helps explain why HTLV-1 particles are morphologically distinct.","lang":"eng"}],"type":"journal_article","publication_identifier":{"eissn":["1545-9985"],"issn":["1545-9993"]},"date_updated":"2026-03-16T12:55:18Z","year":"2025","title":"Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice"},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","day":"01","date_created":"2024-09-15T22:01:42Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"intvolume":"        26","publication_status":"published","oa":1,"file":[{"creator":"dernst","relation":"main_file","file_id":"20124","date_updated":"2025-08-05T11:24:25Z","content_type":"application/pdf","access_level":"open_access","date_created":"2025-08-05T11:24:25Z","file_size":728124,"checksum":"d8d2d6dbce293c9ee6eaa9262e597147","file_name":"2025_AnnalesHenriPoincare_Fialova.pdf","success":1}],"page":"2859-2900","department":[{"_id":"RoSe"}],"publisher":"Springer Nature","status":"public","publication":"Annales Henri Poincare","OA_place":"publisher","external_id":{"arxiv":["2304.13373"],"isi":["001304370000001"]},"quality_controlled":"1","ddc":["510"],"acknowledgement":"First and foremost I am grateful to Jan Philip Solovej for fruitful meetings during (and after) my PhD programme, when this work was done. Further I would like to thank Joshua Hunt, Anna Sisak, Jakub Löwit, Błażej Ruba, Volodymir Riabov, Lukas Schimmer and Georgios Koutentakis for valuable discussions. Many thanks belong to Rafael Benguria for hosting my visit, during which some of the work has been done. I am also grateful to Marina Prokhorova who first initiated the discussion of this project topic and to Annemarie Luger for her valuable comments during my PhD defence and in particular pointing out the qualitative difference in our two main results. I would like to acknowledge support for research on this paper from VILLUM FONDEN through the QMATH Centre of Excellence grant. nr. 10059. This project also received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. I am grateful to the two reviewers for reading carefully my manuscript and pointing out several issues contributing thus significantly to the readability and clarity of this paper.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria).","isi":1,"OA_type":"hybrid","_id":"18074","article_processing_charge":"Yes (via OA deal)","oa_version":"Published Version","author":[{"full_name":"Fialova, Marie","id":"e9c9844d-9e21-11ec-b482-f96fc09f7c4d","first_name":"Marie","last_name":"Fialova"}],"citation":{"short":"M. Fialova, Annales Henri Poincare 26 (2025) 2859–2900.","ista":"Fialova M. 2025. Aharonov–Casher theorems for Dirac operators on manifolds with boundary and APS boundary condition. Annales Henri Poincare. 26, 2859–2900.","chicago":"Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00023-024-01482-7\">https://doi.org/10.1007/s00023-024-01482-7</a>.","mla":"Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>, vol. 26, Springer Nature, 2025, pp. 2859–900, doi:<a href=\"https://doi.org/10.1007/s00023-024-01482-7\">10.1007/s00023-024-01482-7</a>.","ieee":"M. Fialova, “Aharonov–Casher theorems for Dirac operators on manifolds with boundary and APS boundary condition,” <i>Annales Henri Poincare</i>, vol. 26. Springer Nature, pp. 2859–2900, 2025.","ama":"Fialova M. Aharonov–Casher theorems for Dirac operators on manifolds with boundary and APS boundary condition. <i>Annales Henri Poincare</i>. 2025;26:2859-2900. doi:<a href=\"https://doi.org/10.1007/s00023-024-01482-7\">10.1007/s00023-024-01482-7</a>","apa":"Fialova, M. (2025). Aharonov–Casher theorems for Dirac operators on manifolds with boundary and APS boundary condition. <i>Annales Henri Poincare</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00023-024-01482-7\">https://doi.org/10.1007/s00023-024-01482-7</a>"},"abstract":[{"text":"The Aharonov–Casher theorem is a result on the number of the so-called zero modes of a system described by the magnetic Pauli operator in R2. In this paper we address the same question for the Dirac operator on a flat two-dimensional manifold with boundary and Atiyah–Patodi–Singer boundary condition. More concretely we are interested in the plane and a disc with a finite number of circular holes cut out. We consider a smooth compactly supported magnetic field on the manifold and an arbitrary magnetic field inside the holes.","lang":"eng"}],"date_updated":"2025-09-30T10:22:14Z","type":"journal_article","arxiv":1,"publication_identifier":{"issn":["1424-0637"]},"title":"Aharonov–Casher theorems for Dirac operators on manifolds with boundary and APS boundary condition","year":"2025","ec_funded":1,"PlanS_conform":"1","date_published":"2025-08-01T00:00:00Z","volume":26,"corr_author":"1","file_date_updated":"2025-08-05T11:24:25Z","has_accepted_license":"1","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"language":[{"iso":"eng"}],"article_type":"original","scopus_import":"1","month":"08","doi":"10.1007/s00023-024-01482-7"},{"language":[{"iso":"eng"}],"article_type":"original","volume":663,"date_published":"2025-02-01T00:00:00Z","corr_author":"1","has_accepted_license":"1","file_date_updated":"2025-01-13T08:57:57Z","doi":"10.1016/j.jalgebra.2024.08.033","month":"02","scopus_import":"1","citation":{"apa":"Löwit, J. (2025). On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn. <i>Journal of Algebra</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jalgebra.2024.08.033\">https://doi.org/10.1016/j.jalgebra.2024.08.033</a>","ama":"Löwit J. On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn. <i>Journal of Algebra</i>. 2025;663(2):81-118. doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2024.08.033\">10.1016/j.jalgebra.2024.08.033</a>","ieee":"J. Löwit, “On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn,” <i>Journal of Algebra</i>, vol. 663, no. 2. Elsevier, pp. 81–118, 2025.","mla":"Löwit, Jakub. “On modulo ℓ Cohomology of P-Adic Deligne–Lusztig Varieties for GLn.” <i>Journal of Algebra</i>, vol. 663, no. 2, Elsevier, 2025, pp. 81–118, doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2024.08.033\">10.1016/j.jalgebra.2024.08.033</a>.","ista":"Löwit J. 2025. On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn. Journal of Algebra. 663(2), 81–118.","chicago":"Löwit, Jakub. “On modulo ℓ Cohomology of P-Adic Deligne–Lusztig Varieties for GLn.” <i>Journal of Algebra</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.jalgebra.2024.08.033\">https://doi.org/10.1016/j.jalgebra.2024.08.033</a>.","short":"J. Löwit, Journal of Algebra 663 (2025) 81–118."},"abstract":[{"text":"In 1976, Deligne and Lusztig realized the representation theory of finite groups of Lie type inside étale cohomology of certain algebraic varieties. Recently, a p-adic version of this theory started to emerge: there are p-adic Deligne–Lusztig spaces, whose cohomology encodes representation theoretic information for p-adic groups – for instance, it partially realizes the local Langlands correspondence with characteristic zero coefficients. However, the parallel case of coefficients of positive characteristic  ℓ≠p has not been inspected so far. The purpose of this article is to initiate such an inspection. In particular, we relate cohomology of certain p-adic Deligne–Lusztig spaces to Vignéras's modular local Langlands correspondence for GLn.","lang":"eng"}],"oa_version":"Published Version","author":[{"full_name":"Löwit, Jakub","id":"e3b80ae2-eb8e-11eb-b029-9aef4a9108a0","first_name":"Jakub","last_name":"Löwit"}],"title":"On modulo ℓ cohomology of p-adic Deligne–Lusztig varieties for GLn","year":"2025","date_updated":"2025-02-27T12:32:40Z","arxiv":1,"type":"journal_article","publication_identifier":{"issn":["0021-8693"],"eissn":["1090-266X"]},"status":"public","publication":"Journal of Algebra","OA_place":"publisher","file":[{"relation":"main_file","file_id":"18830","creator":"dernst","access_level":"open_access","content_type":"application/pdf","date_updated":"2025-01-13T08:57:57Z","file_name":"2024_JourAlgebra_Loewit.pdf","checksum":"eb240e93c178e48429ad918c9058f1fe","file_size":731175,"date_created":"2025-01-13T08:57:57Z","success":1}],"oa":1,"page":"81-118","department":[{"_id":"TaHa"}],"publisher":"Elsevier","isi":1,"_id":"18154","article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","quality_controlled":"1","external_id":{"arxiv":["2404.11176"],"isi":["001325207800001"]},"ddc":["510"],"day":"01","date_created":"2024-09-29T22:01:37Z","issue":"2","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"       663","publication_status":"published"},{"language":[{"iso":"eng"}],"article_type":"original","date_published":"2025-03-01T00:00:00Z","volume":47,"has_accepted_license":"1","file_date_updated":"2025-04-08T11:17:45Z","month":"03","doi":"10.1007/s00283-024-10358-x","scopus_import":"1","citation":{"apa":"Brunck, F. R., &#38; Kwan, M. A. (2025). Books, Hallways, and social butterflies: A note on sliding block puzzles. <i>Mathematical Intelligencer</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00283-024-10358-x\">https://doi.org/10.1007/s00283-024-10358-x</a>","ama":"Brunck FR, Kwan MA. Books, Hallways, and social butterflies: A note on sliding block puzzles. <i>Mathematical Intelligencer</i>. 2025;47:52-65. doi:<a href=\"https://doi.org/10.1007/s00283-024-10358-x\">10.1007/s00283-024-10358-x</a>","ieee":"F. R. Brunck and M. A. Kwan, “Books, Hallways, and social butterflies: A note on sliding block puzzles,” <i>Mathematical Intelligencer</i>, vol. 47. Springer Nature, pp. 52–65, 2025.","mla":"Brunck, Florestan R., and Matthew Alan Kwan. “Books, Hallways, and Social Butterflies: A Note on Sliding Block Puzzles.” <i>Mathematical Intelligencer</i>, vol. 47, Springer Nature, 2025, pp. 52–65, doi:<a href=\"https://doi.org/10.1007/s00283-024-10358-x\">10.1007/s00283-024-10358-x</a>.","chicago":"Brunck, Florestan R, and Matthew Alan Kwan. “Books, Hallways, and Social Butterflies: A Note on Sliding Block Puzzles.” <i>Mathematical Intelligencer</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00283-024-10358-x\">https://doi.org/10.1007/s00283-024-10358-x</a>.","ista":"Brunck FR, Kwan MA. 2025. Books, Hallways, and social butterflies: A note on sliding block puzzles. Mathematical Intelligencer. 47, 52–65.","short":"F.R. Brunck, M.A. Kwan, Mathematical Intelligencer 47 (2025) 52–65."},"abstract":[{"text":"Interest in sliding block puzzles dates back to the 15-puzzle, seemingly invented by Noyes Chapman in 1874 (see [23] for an account of the fascinating history of the puzzle). The game consists of fifteen movable square blocks numbered \r\n and arranged within a \r\n square box, leaving one empty space (see Figure 1). The task at hand is to start from a given configuration of the numbered blocks and reach the desired target configuration, where the only allowed move is to slide a numbered block into an adjacent empty space. This task seemed to be unpredictably either very easy to accomplish, or completely impossible, and the puzzle turned into a worldwide sensation in the spring of 1880. A particularly challenging instance, known as the 13-15-14 puzzle, consisted of initial and target configurations that differed by a single swap (historically this swap involved the blocks labeled 14 and 15). The craze of this puzzle was such that it consistently made newspaper headlines in 1880, with an article in the New York Times lamenting that it was “threatening our free institutions” [23, p. 9]. Various prizes were offered for anyone who could solve this challenge, beginning with a $25 set of teeth and culminating with Sam Loyd’s famous $1,000 cash prize.","lang":"eng"}],"oa_version":"Published Version","author":[{"id":"6ab6e556-f394-11eb-9cf6-9dfb78f00d8d","full_name":"Brunck, Florestan R","last_name":"Brunck","first_name":"Florestan R"},{"last_name":"Kwan","first_name":"Matthew Alan","orcid":"0000-0002-4003-7567","id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3","full_name":"Kwan, Matthew Alan"}],"title":"Books, Hallways, and social butterflies: A note on sliding block puzzles","year":"2025","date_updated":"2025-05-19T14:00:09Z","type":"journal_article","arxiv":1,"publication_identifier":{"issn":["0343-6993"]},"status":"public","publication":"Mathematical Intelligencer","OA_place":"publisher","oa":1,"file":[{"file_id":"19530","relation":"main_file","creator":"dernst","date_updated":"2025-04-08T11:17:45Z","content_type":"application/pdf","access_level":"open_access","checksum":"c932ebe45c460d4a73f5b2dcca643db1","file_size":1760643,"date_created":"2025-04-08T11:17:45Z","file_name":"2025_MathIntelligencer_Brunck.pdf","success":1}],"page":"52-65","department":[{"_id":"UlWa"},{"_id":"MaKw"}],"publisher":"Springer Nature","acknowledgement":"Open access funding provided by Copenhagen University.","isi":1,"_id":"18157","OA_type":"hybrid","article_processing_charge":"Yes (via OA deal)","external_id":{"arxiv":["2303.09459"],"isi":["001318056000001"]},"quality_controlled":"1","ddc":["510"],"day":"01","date_created":"2024-09-29T22:01:38Z","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"        47","publication_status":"published"},{"article_type":"original","language":[{"iso":"eng"}],"corr_author":"1","file_date_updated":"2025-01-13T09:02:47Z","has_accepted_license":"1","project":[{"call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}],"ec_funded":1,"date_published":"2025-02-01T00:00:00Z","volume":240,"month":"02","doi":"10.1016/j.scico.2024.103212","scopus_import":"1","citation":{"chicago":"Chalupa, Marek, Fabian Mühlböck, Stefanie Muroya Lei, and Thomas A Henzinger. “VAMOS: Middleware for Best-Effort Third-Party Monitoring.” <i>Science of Computer Programming</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.scico.2024.103212\">https://doi.org/10.1016/j.scico.2024.103212</a>.","ista":"Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. 2025. VAMOS: Middleware for best-effort third-party monitoring. Science of Computer Programming. 240(2), 103212.","mla":"Chalupa, Marek, et al. “VAMOS: Middleware for Best-Effort Third-Party Monitoring.” <i>Science of Computer Programming</i>, vol. 240, no. 2, 103212, Elsevier, 2025, doi:<a href=\"https://doi.org/10.1016/j.scico.2024.103212\">10.1016/j.scico.2024.103212</a>.","ieee":"M. Chalupa, F. Mühlböck, S. Muroya Lei, and T. A. Henzinger, “VAMOS: Middleware for best-effort third-party monitoring,” <i>Science of Computer Programming</i>, vol. 240, no. 2. Elsevier, 2025.","short":"M. Chalupa, F. Mühlböck, S. Muroya Lei, T.A. Henzinger, Science of Computer Programming 240 (2025).","apa":"Chalupa, M., Mühlböck, F., Muroya Lei, S., &#38; Henzinger, T. A. (2025). VAMOS: Middleware for best-effort third-party monitoring. <i>Science of Computer Programming</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.scico.2024.103212\">https://doi.org/10.1016/j.scico.2024.103212</a>","ama":"Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. VAMOS: Middleware for best-effort third-party monitoring. <i>Science of Computer Programming</i>. 2025;240(2). doi:<a href=\"https://doi.org/10.1016/j.scico.2024.103212\">10.1016/j.scico.2024.103212</a>"},"article_number":"103212","abstract":[{"text":"As the complexity and criticality of software increase every year, so does the importance of runtime monitoring. Third-party and best-effort monitoring are especially valuable, yet under-explored areas of runtime monitoring. In this context, third-party monitoring means monitoring with a limited knowledge of the monitored software (as it has been developed by a third party). Best-effort monitoring keeps pace with the monitored software at the cost of possibly imprecise verdicts when keeping up with the monitored software would not be feasible. Most existing monitoring frameworks do not support the combination of third-party and best-effort monitoring because they either require the full access to the monitored code or the ability to process all observable events, or both.\r\nWe present a middleware framework, Vamos, for the runtime monitoring of software. Vamos is explicitly designed to support third-party and best-effort scenarios. The design goals of Vamos are (i) efficiency (tracing events with low overhead), (ii) flexibility (the ability to monitor a variety of different event channels, and to connect to a wide range of monitors), and (iii) ease-of-use. To achieve its goals, Vamos combines aspects of event broker and event recognition systems with aspects of stream processing systems.\r\nWe implemented a prototype toolchain for Vamos and conducted a set of experiments demonstrating the usability of the scheme. The results indicate that Vamos enables writing useful yet efficient monitors, and simplifies key aspects of setting up a monitoring system from scratch.","lang":"eng"}],"author":[{"first_name":"Marek","last_name":"Chalupa","full_name":"Chalupa, Marek","id":"87e34708-d6c6-11ec-9f5b-9391e7be2463"},{"last_name":"Mühlböck","orcid":"0000-0003-1548-0177","first_name":"Fabian","id":"6395C5F6-89DF-11E9-9C97-6BDFE5697425","full_name":"Mühlböck, Fabian"},{"full_name":"Muroya Lei, Stefanie","id":"a376de31-8972-11ed-ae7b-d0251c13c8ff","first_name":"Stefanie","last_name":"Muroya Lei"},{"full_name":"Henzinger, Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2985-7724","first_name":"Thomas A","last_name":"Henzinger"}],"oa_version":"Published Version","year":"2025","title":"VAMOS: Middleware for best-effort third-party monitoring","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"12856"}]},"type":"journal_article","publication_identifier":{"issn":["0167-6423"]},"date_updated":"2025-09-09T12:25:29Z","OA_place":"publisher","status":"public","publication":"Science of Computer Programming","department":[{"_id":"ToHe"}],"publisher":"Elsevier","file":[{"success":1,"file_name":"2024_ScienceCompProg_Chalupa.pdf","checksum":"cd93c0c356e479ffccfbe8499b6ba8e2","file_size":1173677,"date_created":"2025-01-13T09:02:47Z","access_level":"open_access","content_type":"application/pdf","date_updated":"2025-01-13T09:02:47Z","file_id":"18831","relation":"main_file","creator":"dernst"}],"oa":1,"isi":1,"_id":"18169","article_processing_charge":"Yes (via OA deal)","OA_type":"hybrid","acknowledgement":"This work was supported in part by the ERC-2020-AdG 101020093. The authors would like to thank the STTT reviewers for their valuable feedback and suggestions.","external_id":{"isi":["001327852600001"]},"quality_controlled":"1","ddc":["000"],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"issue":"2","date_created":"2024-10-06T22:01:10Z","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","intvolume":"       240"}]
