[{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"06","scopus_import":"1","department":[{"_id":"AmDo"}],"title":"A hypothalamic circuit for anticipating future changes in energy balance","article_type":"original","article_processing_charge":"No","external_id":{"pmid":["42235510"]},"doi":"10.1016/j.neuron.2026.05.010","year":"2026","status":"public","date_updated":"2026-06-16T08:35:11Z","date_created":"2026-06-08T09:24:25Z","day":"03","publisher":"Elsevier","date_published":"2026-06-03T00:00:00Z","oa":1,"author":[{"last_name":"Walker","full_name":"Walker, Samuel J.","first_name":"Samuel J."},{"last_name":"Lowenstein","full_name":"Lowenstein, Elijah D.","first_name":"Elijah D."},{"orcid":"0000-0001-5398-6473","last_name":"Douglass","id":"de5f6fda-80fb-11ef-996f-a8c4ecd8e289","full_name":"Douglass, Amelia May Barnett","first_name":"Amelia May Barnett"},{"last_name":"Thomas","first_name":"Callum M.P.","full_name":"Thomas, Callum M.P."},{"full_name":"Madara, Joseph C.","first_name":"Joseph C.","last_name":"Madara"},{"full_name":"Kucukdereli, Hakan","first_name":"Hakan","last_name":"Kucukdereli"},{"last_name":"Barbosa-Meillon","first_name":"Eunice A.","full_name":"Barbosa-Meillon, Eunice A."},{"last_name":"Tao","full_name":"Tao, Jenkang","first_name":"Jenkang"},{"first_name":"Jon M.","full_name":"Resch, Jon M.","last_name":"Resch"},{"full_name":"Lowell, Bradford B.","first_name":"Bradford B.","last_name":"Lowell"}],"publication":"Neuron","abstract":[{"text":"AgRP neurons cause hunger, the drive to seek and consume food. Their activation by fasting is key for survival and is thought to be triggered by feedback when energy stores are low. However, we know that environmental cues can also regulate AgRP neurons since cues that predict future food intake rapidly inhibit AgRP neurons, but is the converse true: can the prediction of future fasting rapidly activate AgRP neurons? Here, we show in mice that such rapid fasting activation of AgRP neurons does occur. This rapid activation is driven by excitatory input from paraventricular hypothalamic (PVH) neurons expressing Sim2, which are bidirectionally sensitive to predictions of future energy state. Thus, cognitively processed contextual information conveyed by PVHSim2 neurons strongly activates AgRP neurons. Lastly, chronic silencing of PVHSim2 neurons causes persistent hypophagia. This PVHSim2-to-AgRP-neuron circuit, by anticipating and preventing negative energy balance, provides an important new dimension of hunger regulation.","lang":"eng"}],"OA_place":"repository","quality_controlled":"1","acknowledgement":"We thank all members of the B.B.L. laboratory for helpful discussions. We\r\nthank the BADERC and BNORC transgenic cores (NIH P30DK057521 and\r\nP30DK046200) for performing embryo injections to generate knockin mouse\r\nlines. We also thank the BIDMC Energy Balance Core (supported by NIH\r\nS10OD028635 and the Boston Area Diabetes Endocrinology Research Centers, P30DK135043), where Marissa Cortopassi performed indirect calorimetry experiments and Alexander Banks assisted with data analysis and interpretation. Confocal imaging was performed at BIDMC’s Confocal Imaging\r\nCore. We thank Chen Wu for assistance in designing knockin mouse lines.\r\nThis work was supported by the NIH (R01DK134427, R01DK096010, and\r\nR01DK075632 to B.B.L.). Authors were supported by an EMBO Long-Term\r\nFellowship (770-2018, S.J.W.), a T32 Postdoctoral Training Fellowship\r\n(5T32DK007516, E.D.L.), the Charles A. King Trust Postdoctoral Research\r\nFellowship program (A.M.D.), and a K99 Career Development Award\r\n(K99HL144923, J.M.R.).","publication_status":"inpress","citation":{"mla":"Walker, Samuel J., et al. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” <i>Neuron</i>, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">10.1016/j.neuron.2026.05.010</a>.","ieee":"S. J. Walker <i>et al.</i>, “A hypothalamic circuit for anticipating future changes in energy balance,” <i>Neuron</i>. Elsevier.","ista":"Walker SJ, Lowenstein ED, Douglass AM, Thomas CMP, Madara JC, Kucukdereli H, Barbosa-Meillon EA, Tao J, Resch JM, Lowell BB. A hypothalamic circuit for anticipating future changes in energy balance. Neuron.","short":"S.J. Walker, E.D. Lowenstein, A.M. Douglass, C.M.P. Thomas, J.C. Madara, H. Kucukdereli, E.A. Barbosa-Meillon, J. Tao, J.M. Resch, B.B. Lowell, Neuron (n.d.).","chicago":"Walker, Samuel J., Elijah D. Lowenstein, Amelia M. Douglass, Callum M.P. Thomas, Joseph C. Madara, Hakan Kucukdereli, Eunice A. Barbosa-Meillon, Jenkang Tao, Jon M. Resch, and Bradford B. Lowell. “A Hypothalamic Circuit for Anticipating Future Changes in Energy Balance.” <i>Neuron</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">https://doi.org/10.1016/j.neuron.2026.05.010</a>.","ama":"Walker SJ, Lowenstein ED, Douglass AM, et al. A hypothalamic circuit for anticipating future changes in energy balance. <i>Neuron</i>. doi:<a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">10.1016/j.neuron.2026.05.010</a>","apa":"Walker, S. J., Lowenstein, E. D., Douglass, A. M., Thomas, C. M. P., Madara, J. C., Kucukdereli, H., … Lowell, B. B. (n.d.). A hypothalamic circuit for anticipating future changes in energy balance. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2026.05.010\">https://doi.org/10.1016/j.neuron.2026.05.010</a>"},"keyword":["hunger","hypothalamus","AGRP neurons","neuroscience","metabolism","homeostasis","feeding","food intake","energy balance","appetite"],"oa_version":"Preprint","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.09.27.678865"}],"_id":"21955","pmid":1,"type":"journal_article","language":[{"iso":"eng"}],"publication_identifier":{"eissn":[" 1097-4199"],"issn":["0896-6273"]},"OA_type":"green"},{"abstract":[{"text":"This thesis investigates algorithmic certification and approximation methods for degenerate semidefinite programs (SDPs) and the singular roots of polynomial systems. In the first part, we present a hybrid symbolic-numeric algorithm for certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating linear matrix inequalities (LMIs) into a structured polynomial system via facial reduction and incidence varieties, we guarantee the existence of an isolated exact solution. This algebraic reduction enables the certification of maximum-rank numerical approximations using methods from algebraic geometry.\r\n\r\nIn the second part, we address the severe ill-conditioning and loss of quadratic convergence that plague standard path-tracking methods near isolated singular roots. To overcome this, we propose tracking algorithms that achieve superlinear convergence without the computational bloat characteristic of classical deflation techniques. By modeling the solution path as a generalized fractional Puiseux series, our approach combines an explicitly derived algebraic predictor with a localized hyperplane desingularization phase during the corrector step. Furthermore, we introduce a continuous path-limit method and an extension of the geometric sequence rule to directly extract exact fractional exponents. This bypasses traditional heuristic trial-and-error methods and explicitly accommodates sparse series expansions. Numerical experiments confirm that our method significantly reduces the cumulative number of matrix inversions while achieving high-accuracy root approximations, even for heavily degenerate systems exhibiting higher coranks.","lang":"eng"}],"OA_place":"publisher","author":[{"first_name":"Jeferson","full_name":"Zapata, Jeferson","id":"00223538-AF8F-11E9-A4C7-F729E6697425","last_name":"Zapata"}],"alternative_title":["ISTA Thesis"],"date_published":"2026-06-09T00:00:00Z","oa":1,"oa_version":"Published Version","publication_status":"published","citation":{"ista":"Zapata J. 2026. Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames. Institute of Science and Technology Austria.","ieee":"J. Zapata, “Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames,” Institute of Science and Technology Austria, 2026.","mla":"Zapata, Jeferson. <i>Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>.","apa":"Zapata, J. (2026). <i>Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>","short":"J. Zapata, Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames, Institute of Science and Technology Austria, 2026.","chicago":"Zapata, Jeferson. “Overcoming Degeneracy and Singularity : Techniques for Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21957\">https://doi.org/10.15479/AT-ISTA-21957</a>.","ama":"Zapata J. Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21957\">10.15479/AT-ISTA-21957</a>"},"acknowledgement":"Funding: Vienna Graduate School on Computational Optimization (FWF), grant DOI: 10.55776/W1260.","degree_awarded":"PhD","related_material":{"record":[{"id":"21144","relation":"part_of_dissertation","status":"public"}]},"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-079-4"]},"language":[{"iso":"eng"}],"type":"dissertation","_id":"21957","has_accepted_license":"1","month":"06","file_date_updated":"2026-06-10T13:33:25Z","supervisor":[{"full_name":"Kolmogorov, Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","corr_author":"1","file":[{"checksum":"b11a959e99d3dcf61040282b5c837141","creator":"jzapata","file_size":40811933,"file_name":"istaustriathesis_JZapata.zip","access_level":"closed","relation":"source_file","content_type":"application/zip","file_id":"21958","date_updated":"2026-06-08T13:20:02Z","date_created":"2026-06-08T13:20:02Z"},{"access_level":"open_access","file_name":"4_Final_Thesis_JZapata_REX.pdf","relation":"main_file","success":1,"content_type":"application/pdf","file_id":"21992","date_updated":"2026-06-10T13:33:25Z","date_created":"2026-06-10T13:33:25Z","checksum":"edf1e5899b2e31505cd1aa3fe8bd4b7f","creator":"jzapata","file_size":2207892}],"page":"89","year":"2026","doi":"10.15479/AT-ISTA-21957","article_processing_charge":"No","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"department":[{"_id":"GradSch"},{"_id":"VlKo"}],"title":"Overcoming degeneracy and singularity : Techniques for semidefinite programs and homotopy continuation endgames","day":"09","date_updated":"2026-06-12T10:37:00Z","date_created":"2026-06-08T13:29:52Z","project":[{"name":"Vienna Graduate School on Computational Optimization","grant_number":"W1260-N35","_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A"}],"status":"public","ddc":["500"],"publisher":"Institute of Science and Technology Austria"},{"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","corr_author":"1","oa":1,"date_published":"2026-06-16T00:00:00Z","file":[{"access_level":"open_access","file_name":"README.txt","relation":"main_file","file_id":"22010","date_updated":"2026-06-15T22:01:57Z","date_created":"2026-06-15T22:01:57Z","success":1,"content_type":"text/plain","file_size":1940,"checksum":"133269a105e996c6c44fdd56128259c7","creator":"akerschb"},{"access_level":"open_access","file_name":"Soliton_Data.zip","relation":"main_file","file_id":"22011","date_updated":"2026-06-15T22:02:07Z","date_created":"2026-06-15T22:02:07Z","success":1,"content_type":"application/zip","file_size":13259747,"checksum":"759f9649c3919f4c4ad37a1d104ea32a","creator":"akerschb"}],"author":[{"first_name":"Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410","full_name":"Kerschbaumer, Aron","last_name":"Kerschbaumer","orcid":"0009-0002-2370-8661"}],"month":"06","file_date_updated":"2026-06-15T22:02:07Z","has_accepted_license":"1","OA_place":"repository","abstract":[{"lang":"eng","text":"Solitons - localized wave packets that travel without spreading - play a central role in understanding transport and properties of nonlinear systems. In quantum many-body systems, however, such robust excitations are typically destroyed by thermalization. Here, we theoretically demonstrate the existence of solitonic excitations in high-energy states of Rydberg atom chains in the regime of strong nearest-neighbor Rydberg blockade. \r\nThese localized wave packets propagate directionally atop a special class of reviving initial states related to quantum many-body scars and are capable of carrying energy. Exhibiting long coherence times, these states constitute a form of non-ergodic quantum dynamics and can be efficiently implemented on Rydberg atom simulators. In this work, in addition to a phenomenological description of solitons, we identify their counterpart in a classical nonlinear dynamical system, demonstrate their potential use in quantum information transfer, and conjecture their relevance for anomalous energy transport reported in numerical studies of Rydberg atom arrays."}],"department":[{"_id":"GradSch"},{"_id":"MaSe"}],"title":"Research Data: \"Quasi-solitons in Rydberg atom chains\"","contributor":[{"last_name":"Kerschbaumer","orcid":"0009-0002-2370-8661","contributor_type":"contact_person","first_name":"Aron","id":"ade85a9c-3200-11ee-973b-91c1eb240410"},{"first_name":"Maksym","id":"47809E7E-F248-11E8-B48F-1D18A9856A87","last_name":"Serbyn","contributor_type":"supervisor","orcid":"0000-0002-2399-5827"},{"first_name":"Jean-Yves Marc","id":"6c292945-a610-11ed-9eec-c3be1ad62a80","last_name":"Desaules","orcid":"0000-0002-3749-6375","contributor_type":"researcher"},{"first_name":"Marko","last_name":"Ljubotina","contributor_type":"researcher"}],"citation":{"chicago":"Kerschbaumer, Aron. “Research Data: ‘Quasi-Solitons in Rydberg Atom Chains.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">https://doi.org/10.15479/AT-ISTA-21960</a>.","short":"A. Kerschbaumer, (2026).","ama":"Kerschbaumer A. Research Data: “Quasi-solitons in Rydberg atom chains.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>","apa":"Kerschbaumer, A. (2026). Research Data: “Quasi-solitons in Rydberg atom chains.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">https://doi.org/10.15479/AT-ISTA-21960</a>","ieee":"A. Kerschbaumer, “Research Data: ‘Quasi-solitons in Rydberg atom chains.’” Institute of Science and Technology Austria, 2026.","mla":"Kerschbaumer, Aron. <i>Research Data: “Quasi-Solitons in Rydberg Atom Chains.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>.","ista":"Kerschbaumer A. 2026. Research Data: ‘Quasi-solitons in Rydberg atom chains’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21960\">10.15479/AT-ISTA-21960</a>."},"article_processing_charge":"No","tmp":{"short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"doi":"10.15479/AT-ISTA-21960","year":"2026","oa_version":"Published Version","status":"public","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020"}],"date_created":"2026-06-09T07:17:50Z","date_updated":"2026-06-16T08:00:38Z","day":"16","_id":"21960","publisher":"Institute of Science and Technology Austria","ec_funded":1,"type":"research_data"},{"oa_version":"Preprint","acknowledgement":"We thank A. Heger (IST Austria Preclinical Facility), A. Sommer (VBCF GmbH, NGS Unit), and A.\r\nNicolas (IST Austria Lab Support Facility / Mass Spectrometry Facility) for technical support; K. Ferencak,\r\nI. Aykara, P. Hirschfeld, E. Fisher, S. Laukoter, L. Andersen for initial experiments and/or assistance; and\r\nall members of the Hippenmeyer lab for discussion. This research was supported by the Scientific Service\r\nUnits (SSU) of IST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). R.B. received support from FWF Meitner-Programm (M 2416). This\r\nwork was also supported by IST Austria institutional funds; the People Programme (Marie Curie Actions)\r\nof the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement\r\nNo 618444 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation programme (grant agreement No 725780 LinPro) to S.H.","publication_status":"submitted","citation":{"ista":"Villalba Requena A, Beattie RJ, Pauler F, Streicher C, Miranda O, Krausgruber T, Senekowitsch M, Farlik M, Bock C, Rülicke T, Hippenmeyer S. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","mla":"Villalba Requena, Ana, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","ieee":"A. Villalba Requena <i>et al.</i>, “Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner,” <i>bioRxiv</i>. .","apa":"Villalba Requena, A., Beattie, R. J., Pauler, F., Streicher, C., Miranda, O., Krausgruber, T., … Hippenmeyer, S. (n.d.). Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>","chicago":"Villalba Requena, Ana, Robert J Beattie, Florian Pauler, Carmen Streicher, Osvaldo Miranda, Thomas Krausgruber, Martin Senekowitsch, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>.","ama":"Villalba Requena A, Beattie RJ, Pauler F, et al. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>","short":"A. Villalba Requena, R.J. Beattie, F. Pauler, C. Streicher, O. Miranda, T. Krausgruber, M. Senekowitsch, M. Farlik, C. Bock, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.)."},"OA_place":"repository","abstract":[{"text":"The generation of faithful cell-type diversity and correct projection neuron numbers is essential for cerebral cortex development. Corticogenesis is however susceptible to genetic interference of critical signaling pathways, including mutations in Mtor/Rptor that lead to microcephaly. How the loss of Rptor/mTORC1 function affects cortical developmental programs, at single cell level, is still unknown. Here, we utilized Mosaic Analysis with Double Markers (MADM) technology to probe Rptor gene function upon sparse single cell- or global tissue-wide ablation. We found that tissue-wide effects drive the etiology of cortical microcephaly upon loss of Rptor, rather than deficits in projection neuron genesis. Conversely, Rptor function is cell-autonomously required for postnatal projection neuron survival in a highly cell-type-specific manner. Collectively, our results suggest that the fine balance of precise cell-type-specific cell-autonomous Rptor/mTORC1 function in concert with non-cell-autonomous tissue-wide effects is essential for the development of a properly-sized cerebral cortex with accurate projection neuron diversity.","lang":"eng"}],"date_published":"2026-05-05T00:00:00Z","oa":1,"publication":"bioRxiv","author":[{"full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana","orcid":"0000-0002-5615-5277","last_name":"Villalba Requena"},{"first_name":"Robert J","full_name":"Beattie, Robert J","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87","last_name":"Beattie","orcid":"0000-0002-8483-8753"},{"last_name":"Pauler","orcid":"0000-0002-7462-0048","first_name":"Florian","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian"},{"first_name":"Carmen","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher"},{"first_name":"Osvaldo","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","last_name":"Miranda","orcid":"0000-0001-6618-6889"},{"first_name":"Thomas","full_name":"Krausgruber, Thomas","last_name":"Krausgruber"},{"last_name":"Senekowitsch","first_name":"Martin","full_name":"Senekowitsch, Martin"},{"first_name":"Matthias","full_name":"Farlik, Matthias","last_name":"Farlik"},{"last_name":"Bock","first_name":"Christoph","full_name":"Bock, Christoph"},{"last_name":"Rülicke","first_name":"Thomas","full_name":"Rülicke, Thomas"},{"last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"}],"language":[{"iso":"eng"}],"type":"preprint","OA_type":"green","_id":"21962","main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.05.01.722172"}],"doi":"10.64898/2026.05.01.722172","year":"2026","title":"Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner","department":[{"_id":"SiHi"}],"tmp":{"short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"article_processing_charge":"No","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"05","ec_funded":1,"ddc":["570"],"date_created":"2026-06-09T08:08:18Z","date_updated":"2026-06-16T08:45:25Z","day":"05","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"Bio"}],"status":"public","project":[{"name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex","grant_number":"M02416","call_identifier":"FWF","_id":"264E56E2-B435-11E9-9278-68D0E5697425"},{"_id":"25D61E48-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanisms of Cerebral Cortex Development","grant_number":"618444","call_identifier":"FP7"},{"_id":"260018B0-B435-11E9-9278-68D0E5697425","grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","call_identifier":"H2020"}]},{"title":"Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production","department":[{"_id":"SiHi"},{"_id":"PreCl"},{"_id":"GradSch"}],"tmp":{"short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"article_processing_charge":"No","doi":"10.64898/2026.05.01.722191","year":"2026","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","month":"05","has_accepted_license":"1","ddc":["570"],"ec_funded":1,"status":"public","project":[{"grant_number":"F7805","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E"},{"_id":"260018B0-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}],"date_created":"2026-06-09T08:08:53Z","date_updated":"2026-06-16T08:57:20Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"day":"05","acknowledgement":"We thank Kay-Uwe Wagner (Wayne State University) for generously sharing Jak1/2–flox mouse lines; A.\r\nSommer (VBCF GmbH, NGS Unit) for technical support; N. Kim, V. Mick, S. Schnabl, S. Gobeil, and L.\r\nAndersen for technical assistance; all members of the Hippenmeyer lab for discussion and B. Novitch for\r\ncomments on earlier versions of the manuscript. This research was supported by the Scientific Service Units\r\n(SSU) of IST Austria through resources provided by the Imaging and Optics Facility (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). O.A.M received support from the Austrian Academy of Sciences\r\nÖAW (DOC 186584), and N.A. from FWF Elise Richter Program (Grant V1041T). This work was also\r\nsupported by IST Austria institutional funds; FWF SFB F78 (Neuro Stem Modulation) to S.H., and the\r\nEuropean Research Council (ERC) under the European Union’s Horizon 2020 research and innovation\r\nprogramme (grant agreement No 725780 LinPro) to S.H.","citation":{"ista":"Miranda O, Contreras X, Pauler F, Davaatseren A, Amberg N, Streicher C, Villalba Requena A, Heger A-M, Marie C, Hassan BA, Rülicke T, Hippenmeyer S. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","ieee":"O. Miranda <i>et al.</i>, “Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production,” <i>bioRxiv</i>. .","mla":"Miranda, Osvaldo, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","apa":"Miranda, O., Contreras, X., Pauler, F., Davaatseren, A., Amberg, N., Streicher, C., … Hippenmeyer, S. (n.d.). Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>","chicago":"Miranda, Osvaldo, Ximena Contreras, Florian Pauler, Amarbayasgalan Davaatseren, Nicole Amberg, Carmen Streicher, Ana Villalba Requena, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>.","short":"O. Miranda, X. Contreras, F. Pauler, A. Davaatseren, N. Amberg, C. Streicher, A. Villalba Requena, A.-M. Heger, C. Marie, B.A. Hassan, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","ama":"Miranda O, Contreras X, Pauler F, et al. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>"},"publication_status":"submitted","oa_version":"Preprint","oa":1,"date_published":"2026-05-05T00:00:00Z","author":[{"orcid":"0000-0001-6618-6889","last_name":"Miranda","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","first_name":"Osvaldo"},{"last_name":"Contreras","full_name":"Contreras, Ximena","id":"475990FE-F248-11E8-B48F-1D18A9856A87","first_name":"Ximena"},{"first_name":"Florian","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian","last_name":"Pauler","orcid":"0000-0002-7462-0048"},{"first_name":"Amarbayasgalan","id":"70ADC922-B424-11E9-99E3-BA18E6697425","full_name":"Davaatseren, Amarbayasgalan","last_name":"Davaatseren"},{"first_name":"Nicole","full_name":"Amberg, Nicole","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","last_name":"Amberg","orcid":"0000-0002-3183-8207"},{"last_name":"Streicher","first_name":"Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","full_name":"Streicher, Carmen"},{"orcid":"0000-0002-5615-5277","last_name":"Villalba Requena","full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","first_name":"Ana"},{"id":"4B76FFD2-F248-11E8-B48F-1D18A9856A87","full_name":"Heger, Anna-Magdalena","first_name":"Anna-Magdalena","last_name":"Heger"},{"last_name":"Marie","first_name":"Corentine","full_name":"Marie, Corentine"},{"full_name":"Hassan, Bassem A.","first_name":"Bassem A.","last_name":"Hassan"},{"full_name":"Rülicke, Thomas","first_name":"Thomas","last_name":"Rülicke"},{"first_name":"Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061"}],"publication":"bioRxiv","OA_place":"repository","abstract":[{"lang":"eng","text":"The cerebral cortex consists of immense numbers of neuronal and glial cell-types derived from radial glial progenitor (RGP) cells. How RGPs generate appropriate quantities of distinct cortical cell-types to safeguard a brain of correct size, is not well understood. However, genetic aberration in human, including mutations in PTEN, lead to cortical malformation such as macrocephaly, albeit with unknown etiology. Here we utilized Mosaic Analysis with Double Markers (MADM)-based clonal analysis and single cell phenotyping to decipher the role of Pten in neurogenic and gliogenic RGP lineage progression during cortical ontogeny. While neurogenic RGP lineage progression and projection neuron production was moderately altered in the absence of Pten, cortical astrocyte production was drastically increased. Through genetic epistasis experiments we show that the loss of Pten uncouples astrocyte generation from essential growth factor signaling hubs, funneling into MAPK. Collectively, our results suggest that Pten regulates RGP lineage progression with distinct sequential functions in cortical projection neurogenesis and astrocyte production to ensure the emergence of a correctly-sized cerebral cortex."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.64898/2026.05.01.722191"}],"_id":"21963","type":"preprint","language":[{"iso":"eng"}],"OA_type":"green"},{"OA_type":"green","language":[{"iso":"eng"}],"type":"preprint","_id":"21968","main_file_link":[{"url":"https://doi.org/10.1101/2025.04.09.647826","open_access":"1"}],"day":"23","date_created":"2026-06-09T12:26:11Z","date_updated":"2026-06-12T12:43:34Z","related_material":{"record":[{"id":"21918","relation":"dissertation_contains","status":"public"}]},"project":[{"grant_number":"26293","name":"The impact of deleterious mutations on small populations","_id":"34d33d68-11ca-11ed-8bc3-ec13763c0ca8"}],"status":"public","oa_version":"Preprint","year":"2026","doi":"10.1101/2025.04.09.647826","tmp":{"short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"article_processing_charge":"No","citation":{"ista":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. bioRxiv, <a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>.","ieee":"K. Khudiakova, N. H. Barton, and G. Arnqvist, “Sign epistasis extends the effects of balancing selection on genetic diversity,” <i>bioRxiv</i>. .","mla":"Khudiakova, Kseniia, et al. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>.","apa":"Khudiakova, K., Barton, N. H., &#38; Arnqvist, G. (n.d.). Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>","short":"K. Khudiakova, N.H. Barton, G. Arnqvist, BioRxiv (n.d.).","ama":"Khudiakova K, Barton NH, Arnqvist G. Sign epistasis extends the effects of balancing selection on genetic diversity. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.04.09.647826\">10.1101/2025.04.09.647826</a>","chicago":"Khudiakova, Kseniia, Nicholas H Barton, and Goran Arnqvist. “Sign Epistasis Extends the Effects of Balancing Selection on Genetic Diversity.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.04.09.647826\">https://doi.org/10.1101/2025.04.09.647826</a>."},"publication_status":"draft","title":"Sign epistasis extends the effects of balancing selection on genetic diversity","department":[{"_id":"NiBa"},{"_id":"JaMa"}],"acknowledgement":"This work was funded by grants from the Swedish Research Council (2023-03730 to G.A.) and the DOC fellowship from the Austrian Academy of Science (26293 to K.K.).","OA_place":"repository","abstract":[{"text":"Balancing selection, a form of selection that maintains genetic diversity, is difficult to detect, and the importance of balancing selection for the maintenance of genetic variation may be larger than often assumed. We model the possibility that the diversity-promoting effects of balancing selection extend to other loci that show sign epistasis with a locus under balancing selection. Rather than focusing on overdominance, as was done in previous efforts, we explore the effects of negative frequency dependence and show that this has important effects on the conditions under which the diversity-promoting effect of epistasis can occur in diploids. Our results show that not only recombination rate but also the dominance of sign epistasis are key parameters that determine the maintenance of polymorphism beyond the locus under direct balancing selection. We suggest that the effect we explore may play a significant role, especially when balancing selection acts on major effect loci.","lang":"eng"}],"month":"04","publication":"bioRxiv","author":[{"first_name":"Kseniia","id":"4E6DC800-AE37-11E9-AC72-31CAE5697425","full_name":"Khudiakova, Kseniia","last_name":"Khudiakova","orcid":"0000-0002-6246-1465"},{"first_name":"Nicholas H","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","orcid":"0000-0002-8548-5240"},{"first_name":"Goran","full_name":"Arnqvist, Goran","last_name":"Arnqvist"}],"oa":1,"date_published":"2026-04-23T00:00:00Z","corr_author":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"},{"status":"public","project":[{"name":"Quantitative Unbiased Shape Analysis with Geometry & Topology","grant_number":"ESP 9584724","_id":"9106a876-16d5-11f0-9cad-bbf11c9952f9"}],"license":"https://opensource.org/licenses/MIT","date_created":"2026-06-09T19:19:13Z","date_updated":"2026-06-15T23:00:03Z","day":"15","publisher":"Institute of Science and Technology Austria","_id":"21971","type":"software","oa":1,"file":[{"relation":"main_file","file_name":"LICENSE","access_level":"open_access","date_created":"2026-06-09T19:16:02Z","date_updated":"2026-06-09T19:16:02Z","file_id":"21974","content_type":"application/octet-stream","success":1,"file_size":1081,"creator":"ybleile","checksum":"48f633b6767c4b15dd6220ca2b4dc175"},{"file_size":11308032,"checksum":"de25d0b224acbde3d38f837fdd8f97d5","creator":"ybleile","file_name":"quadrix-x64.exe","access_level":"open_access","relation":"main_file","file_id":"21975","date_created":"2026-06-09T19:16:27Z","date_updated":"2026-06-09T19:16:27Z","success":1,"content_type":"application/octet-stream"},{"checksum":"a7b94a7380dc178e76ebdba9f1fa45c2","creator":"ybleile","file_size":10655744,"success":1,"content_type":"application/octet-stream","file_id":"21976","date_updated":"2026-06-09T19:16:28Z","date_created":"2026-06-09T19:16:28Z","file_name":"quadrix-arm64.exe","access_level":"open_access","relation":"main_file"},{"creator":"ybleile","checksum":"2404aa8619a56668bd95032791ee1250","file_size":2032,"content_type":"application/zip","success":1,"date_created":"2026-06-09T19:16:27Z","date_updated":"2026-06-09T19:16:27Z","file_id":"21977","relation":"main_file","access_level":"open_access","file_name":"Quadrix Desktop.app.zip"},{"file_size":12187896,"creator":"ybleile","checksum":"106930f81563c5c719a5f4030b5ca5ed","date_created":"2026-06-09T19:16:40Z","date_updated":"2026-06-09T19:16:40Z","file_id":"21978","content_type":"application/octet-stream","success":1,"relation":"main_file","access_level":"open_access","file_name":"quadrix-arm64"},{"creator":"ybleile","checksum":"0e6ba129318446676f220087e7e6ff41","file_size":20587592,"content_type":"application/octet-stream","success":1,"date_updated":"2026-06-09T19:16:52Z","date_created":"2026-06-09T19:16:52Z","file_id":"21979","relation":"main_file","file_name":"quadrix-x64","access_level":"open_access"},{"relation":"main_file","access_level":"open_access","file_name":"Quadrix.zip","date_created":"2026-06-09T19:19:12Z","date_updated":"2026-06-09T19:19:12Z","file_id":"21972","content_type":"application/gzip","file_size":1914198,"creator":"pub-gitlab-bot","checksum":"f0b03385d17df049219465ab7403fe09"},{"relation":"supplementary_material","access_level":"open_access","file_name":"THIRD_PARTY_LICENSES.zip","date_updated":"2026-06-10T19:09:38Z","date_created":"2026-06-10T19:09:38Z","file_id":"21993","content_type":"application/zip","file_size":37557,"creator":"ybleile","checksum":"ede0bbb24bf41ab4009cf1b6a9009671"},{"creator":"ybleile","checksum":"f3c5fcc62c88e449ab5c660244df5aef","file_size":3839,"content_type":"text/markdown","success":1,"date_created":"2026-06-15T08:13:32Z","date_updated":"2026-06-15T08:13:32Z","file_id":"22009","relation":"main_file","file_name":"README.md","access_level":"open_access"},{"content_type":"application/gzip","date_updated":"2026-06-15T08:14:24Z","date_created":"2026-06-15T08:14:24Z","file_id":"22008","relation":"main_file","file_name":"Quadrix.zip","access_level":"open_access","creator":"pub-gitlab-bot","checksum":"aa74828c3165aafcdee4ddcc9ecd37ac","file_size":1912923}],"date_published":"2026-06-15T00:00:00Z","corr_author":"1","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","month":"06","file_date_updated":"2026-06-15T08:14:24Z","author":[{"last_name":"Bleile","orcid":"0000-0002-4861-9174","first_name":"Yossi","id":"920a7385-7995-11ef-9bfd-8c434cd8f3c2","full_name":"Bleile, Yossi"},{"first_name":"Emanuele","full_name":"Cortinovis, Emanuele","last_name":"Cortinovis"}],"has_accepted_license":"1","abstract":[{"lang":"eng","text":"A Rust library for analyzing dendritic structures using quadric matrices. This project provides efficient tools for representing dendritic trees, computing quadric error metrics, and visualizing eigenvalue distributions on hexagonal plots.\r\n\r\nThis library implements quadric-based geometric analysis of dendritic structures, commonly found in neuroscience applications. Key features include:\r\n\r\nTree data structures: Hierarchical vertex and edge representations for dendritic trees\r\nQuadric matrices: Computation of quadric error metrics for edges and vertices\r\nVisualisation: Hexagonal plot generation using NormPolar transformations\r\nInteractive tools: Desktop application with plotting capabilities"}],"department":[{"_id":"HeEd"}],"title":"Quadrix","tmp":{"legal_code_url":"https://opensource.org/licenses/MIT","short":"MIT","name":"The MIT License"},"citation":{"ieee":"Y. Bokor Bleile and E. Cortinovis, “Quadrix.” Institute of Science and Technology Austria, 2026.","mla":"Bokor Bleile, Yossi, and Emanuele Cortinovis. <i>Quadrix</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>.","ista":"Bokor Bleile Y, Cortinovis E. 2026. Quadrix, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>.","short":"Y. Bokor Bleile, E. Cortinovis, (2026).","ama":"Bokor Bleile Y, Cortinovis E. Quadrix. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21971\">10.15479/AT-ISTA-21971</a>","chicago":"Bokor Bleile, Yossi, and Emanuele Cortinovis. “Quadrix.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">https://doi.org/10.15479/AT-ISTA-21971</a>.","apa":"Bokor Bleile, Y., &#38; Cortinovis, E. (2026). Quadrix. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21971\">https://doi.org/10.15479/AT-ISTA-21971</a>"},"doi":"10.15479/AT-ISTA-21971","keyword":["quadratics","mathematics","dendrites","geometry","topology"],"year":"2026"},{"author":[{"first_name":"Artem","id":"83ed7901-7380-11f0-bf20-a0788d5e654d","full_name":"Gulyaev, Artem","last_name":"Gulyaev"},{"orcid":"0009-0007-2542-7878","last_name":"Hazarika","id":"d87714c4-663d-11f0-bd06-caece19833e5","full_name":"Hazarika, Jyotisman","first_name":"Jyotisman"},{"first_name":"Zhen-Fei","full_name":"Liu, Zhen-Fei","last_name":"Liu"},{"first_name":"Latha","full_name":"Venkataraman, Latha","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf","last_name":"Venkataraman","orcid":"0000-0002-6957-6089"}],"publication":"Nano Letters","date_published":"2026-06-01T00:00:00Z","oa":1,"OA_place":"publisher","PlanS_conform":"1","abstract":[{"text":"Despite significant progress in the field of molecular electronics over the last two decades, the quantitative prediction of metal-molecule-metal junction conductance remains a challenge. The standard computational framework combines density functional theory (DFT) with nonequilibrium Green’s functions (NEGF) using low-rung exchange-correlation functionals such as PBE, which overestimate the conductances. More advanced correction methods exist but require complex workflows and high computational cost, limiting their accessibility. Here, we introduce a physically motivated approach that approximates results obtained with high-rung functionals. Our method fits the PBE-calculated transmission to a Breit-Wigner form and subsequently refines the fit parameters using molecular orbital energies and metal densities of states computed for the isolated subsystems with high-rung functionals. This approach is applicable to a broad range of molecular junctions yielding conductance values in quantitative agreement with experiments. Our approach is simple, low-cost, and accurate, making it well-suited for routine and large-scale prediction of single-molecule junction conductance.","lang":"eng"}],"publication_status":"published","citation":{"ieee":"A. Gulyaev, J. Hazarika, Z.-F. Liu, and L. Venkataraman, “A computationally efficient and accurate method for predicting conductance of single-molecule junctions,” <i>Nano Letters</i>, vol. 26, no. 22. American Chemical Society, pp. 7429–7434, 2026.","mla":"Gulyaev, Artem, et al. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>, vol. 26, no. 22, American Chemical Society, 2026, pp. 7429–7434, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">10.1021/acs.nanolett.6c01462</a>.","ista":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. 2026. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. Nano Letters. 26(22), 7429–7434.","short":"A. Gulyaev, J. Hazarika, Z.-F. Liu, L. Venkataraman, Nano Letters 26 (2026) 7429–7434.","chicago":"Gulyaev, Artem, Jyotisman Hazarika, Zhen-Fei Liu, and Latha Venkataraman. “A Computationally Efficient and Accurate Method for Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">https://doi.org/10.1021/acs.nanolett.6c01462</a>.","ama":"Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. A computationally efficient and accurate method for predicting conductance of single-molecule junctions. <i>Nano Letters</i>. 2026;26(22):7429–7434. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">10.1021/acs.nanolett.6c01462</a>","apa":"Gulyaev, A., Hazarika, J., Liu, Z.-F., &#38; Venkataraman, L. (2026). A computationally efficient and accurate method for predicting conductance of single-molecule junctions. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.6c01462\">https://doi.org/10.1021/acs.nanolett.6c01462</a>"},"acknowledgement":"This work was supported primarily by the Institute of Science and Technology Austria. L.V. was supported in part by the National Science Foundation (No. NSF-DMR 2241180). Z.-F.L. was supported by an NSF CAREER Award, No. DMR-2044552 and an Alfred P. Sloan Research Fellowship, No. FG-2024-21750.","quality_controlled":"1","oa_version":"Published Version","_id":"21980","publication_identifier":{"issn":["1530-6984"],"eissn":["1530-6992"]},"issue":"22","OA_type":"hybrid","volume":26,"pmid":1,"language":[{"iso":"eng"}],"type":"journal_article","file_date_updated":"2026-06-16T09:11:35Z","month":"06","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"date_updated":"2026-06-16T09:11:35Z","date_created":"2026-06-16T09:11:35Z","file_id":"22013","content_type":"application/pdf","success":1,"relation":"main_file","access_level":"open_access","file_name":"2026_NanoLetters_Gulyaev.pdf","file_size":3362800,"creator":"dernst","checksum":"897551374cac28e0db26dcb0b676b8e7"}],"scopus_import":"1","has_accepted_license":"1","article_processing_charge":"Yes (via OA deal)","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"letter_note","title":"A computationally efficient and accurate method for predicting conductance of single-molecule junctions","department":[{"_id":"LaVe"},{"_id":"GradSch"}],"page":"7429–7434","year":"2026","external_id":{"pmid":["42223342"]},"doi":"10.1021/acs.nanolett.6c01462","intvolume":"        26","status":"public","day":"01","date_updated":"2026-06-16T09:13:30Z","date_created":"2026-06-10T07:27:19Z","ddc":["540"],"publisher":"American Chemical Society"},{"publisher":"Elsevier","ddc":["000"],"intvolume":"       227","status":"public","day":"21","date_updated":"2026-06-16T09:23:39Z","date_created":"2026-06-10T07:29:13Z","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","title":"An easier way to compute 2-cocycles coming from a reduction for semidirect products","department":[{"_id":"GradSch"}],"article_type":"original","year":"2026","doi":"10.1016/j.geomphys.2026.105878","external_id":{"arxiv":["2509.16169"]},"month":"05","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1016/j.geomphys.2026.105878","open_access":"1"}],"_id":"21981","OA_type":"hybrid","volume":227,"article_number":"105878","publication_identifier":{"eissn":["1879-1662"],"issn":["0393-0440"]},"language":[{"iso":"eng"}],"type":"journal_article","arxiv":1,"publication_status":"epub_ahead","citation":{"apa":"Goncharov, V. (2026). An easier way to compute 2-cocycles coming from a reduction for semidirect products. <i>Journal of Geometry and Physics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">https://doi.org/10.1016/j.geomphys.2026.105878</a>","ama":"Goncharov V. An easier way to compute 2-cocycles coming from a reduction for semidirect products. <i>Journal of Geometry and Physics</i>. 2026;227. doi:<a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">10.1016/j.geomphys.2026.105878</a>","chicago":"Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">https://doi.org/10.1016/j.geomphys.2026.105878</a>.","short":"V. Goncharov, Journal of Geometry and Physics 227 (2026).","ista":"Goncharov V. 2026. An easier way to compute 2-cocycles coming from a reduction for semidirect products. Journal of Geometry and Physics. 227, 105878.","mla":"Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>, vol. 227, 105878, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.geomphys.2026.105878\">10.1016/j.geomphys.2026.105878</a>.","ieee":"V. Goncharov, “An easier way to compute 2-cocycles coming from a reduction for semidirect products,” <i>Journal of Geometry and Physics</i>, vol. 227. Elsevier, 2026."},"quality_controlled":"1","oa_version":"Published Version","publication":"Journal of Geometry and Physics","author":[{"full_name":"Goncharov, Viacheslav","id":"8a0e2993-7114-11f0-b60e-f50e633649d8","first_name":"Viacheslav","last_name":"Goncharov"}],"date_published":"2026-05-21T00:00:00Z","oa":1,"PlanS_conform":"1","OA_place":"publisher","abstract":[{"lang":"eng","text":"For Hamiltonian actions of semidirect products G = FxH, we study 2-cocycles arising from residual Hamiltonian actions of F on Hamiltonian reductions for H. The motivation comes from the study of Teichmüller spaces for surfaces with boundary, which carry Hamiltonian actions of the Virasoro algebra. In this paper, we give a general setup for the problem, and we suggest an easier way to obtain the Gelfand-Fuchs 2-cocycles for Hamiltonian actions on Teichmüller spaces."}]},{"_id":"21982","language":[{"iso":"eng"}],"type":"journal_article","OA_type":"hybrid","volume":113,"article_number":"L053502","issue":"5","publication_identifier":{"eissn":["2470-0053"],"issn":["2470-0045"]},"arxiv":1,"acknowledgement":"This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop and the Scientific Computing Facility. J.B. acknowledges funding from the European Union's Horizon research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101106500.","quality_controlled":"1","citation":{"ieee":"V. L. Diaz Melian, I. C. Lenton, J. Binysh, A. Souslov, and S. R. Waitukaitis, “Geometry of the vapor layer under a Leidenfrost hydrogel sphere,” <i>Physical Review E</i>, vol. 113, no. 5. American Physical Society, 2026.","mla":"Diaz Melian, Vicente L., et al. “Geometry of the Vapor Layer under a Leidenfrost Hydrogel Sphere.” <i>Physical Review E</i>, vol. 113, no. 5, L053502, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/m7gr-2t6j\">10.1103/m7gr-2t6j</a>.","ista":"Diaz Melian VL, Lenton IC, Binysh J, Souslov A, Waitukaitis SR. 2026. Geometry of the vapor layer under a Leidenfrost hydrogel sphere. Physical Review E. 113(5), L053502.","chicago":"Diaz Melian, Vicente L, Isaac C Lenton, Jack Binysh, Anton Souslov, and Scott R Waitukaitis. “Geometry of the Vapor Layer under a Leidenfrost Hydrogel Sphere.” <i>Physical Review E</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/m7gr-2t6j\">https://doi.org/10.1103/m7gr-2t6j</a>.","ama":"Diaz Melian VL, Lenton IC, Binysh J, Souslov A, Waitukaitis SR. Geometry of the vapor layer under a Leidenfrost hydrogel sphere. <i>Physical Review E</i>. 2026;113(5). doi:<a href=\"https://doi.org/10.1103/m7gr-2t6j\">10.1103/m7gr-2t6j</a>","short":"V.L. Diaz Melian, I.C. Lenton, J. Binysh, A. Souslov, S.R. Waitukaitis, Physical Review E 113 (2026).","apa":"Diaz Melian, V. L., Lenton, I. C., Binysh, J., Souslov, A., &#38; Waitukaitis, S. R. (2026). Geometry of the vapor layer under a Leidenfrost hydrogel sphere. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/m7gr-2t6j\">https://doi.org/10.1103/m7gr-2t6j</a>"},"publication_status":"published","oa_version":"Published Version","oa":1,"date_published":"2026-05-14T00:00:00Z","publication":"Physical Review E","author":[{"last_name":"Diaz Melian","first_name":"Vicente L","id":"b6798902-eea0-11ea-9cbc-a8e14286c631","full_name":"Diaz Melian, Vicente L"},{"orcid":"0000-0002-5010-6984","last_name":"Lenton","id":"a550210f-223c-11ec-8182-e2d45e817efb","full_name":"Lenton, Isaac C","first_name":"Isaac C"},{"last_name":"Binysh","full_name":"Binysh, Jack","first_name":"Jack"},{"last_name":"Souslov","first_name":"Anton","full_name":"Souslov, Anton"},{"last_name":"Waitukaitis","orcid":"0000-0002-2299-3176","first_name":"Scott R","full_name":"Waitukaitis, Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87"}],"OA_place":"publisher","abstract":[{"text":"A floating Leidenfrost droplet exhibits curvature inversion of its underside, due to the balance of vapor pressure and surface tension. Using interferometric imaging, we find different behavior for a levitated hydrogel sphere. Curvature inversion is observed briefly just after deposition, but quickly gives way to a steady state with no inversion. We show the essential role of vaporization in shaping the underbelly of the hydrogel, where changes due to direct mass loss are more significant than the balance of vapor pressure and elastic forces.","lang":"eng"}],"PlanS_conform":"1","publisher":"American Physical Society","ddc":["530"],"status":"public","intvolume":"       113","date_updated":"2026-06-16T11:24:18Z","date_created":"2026-06-10T07:36:41Z","day":"14","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"ScienComp"}],"title":"Geometry of the vapor layer under a Leidenfrost hydrogel sphere","department":[{"_id":"ScWa"},{"_id":"GradSch"}],"article_type":"letter_note","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","external_id":{"arxiv":["2507.04982"]},"doi":"10.1103/m7gr-2t6j","year":"2026","file":[{"access_level":"open_access","file_name":"2026_PhysicalReviewE_DiazMelian.pdf","relation":"main_file","file_id":"22014","date_updated":"2026-06-16T11:21:53Z","date_created":"2026-06-16T11:21:53Z","success":1,"content_type":"application/pdf","file_size":3173197,"checksum":"902cc8d177c8d3ae9cfe07c30375c9a9","creator":"dernst"}],"corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-06-16T11:21:53Z","month":"05","has_accepted_license":"1","scopus_import":"1"},{"publisher":"Elsevier","ddc":["570"],"date_created":"2026-06-10T07:37:12Z","date_updated":"2026-06-16T12:37:02Z","day":"09","status":"public","intvolume":"        99","doi":"10.1016/j.gde.2026.102483","external_id":{"arxiv":["2601.19681"]},"year":"2026","title":"Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps","department":[{"_id":"GradSch"},{"_id":"CaGu"},{"_id":"GaTk"}],"article_type":"original","article_processing_charge":"Yes (via OA deal)","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"has_accepted_license":"1","scopus_import":"1","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"05","type":"journal_article","language":[{"iso":"eng"}],"OA_type":"hybrid","volume":99,"publication_identifier":{"issn":["0959-437X"],"eissn":["1879-0380"]},"article_number":"102483","_id":"21983","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.gde.2026.102483"}],"arxiv":1,"oa_version":"Published Version","quality_controlled":"1","acknowledgement":"We thank Nick Barton and Noa Ottilie Borst for essential contributions to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship, jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science and Technology Austria (ISTA).\r\nThis study was supported by the European Molecular Biology Laboratory (J.C.); the European Molecular Biology Laboratory Interdisciplinary Postdoc Programme (EIPOD) under the Marie Skłodowska-Curie Actions cofund (S.H.A.).","publication_status":"published","citation":{"apa":"Mascolo, E., Körei, R. E., Herrera-Álvarez, S., Guet, C. C., Crocker, J., &#38; Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. <i>Current Opinion in Genetics &#38; Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2026.102483\">https://doi.org/10.1016/j.gde.2026.102483</a>","short":"E. Mascolo, R.E. Körei, S. Herrera-Álvarez, C.C. Guet, J. Crocker, G. Tkačik, Current Opinion in Genetics &#38; Development 99 (2026).","chicago":"Mascolo, Elia, Reka E Körei, Santiago Herrera-Álvarez, Calin C Guet, Justin Crocker, and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 1: Simulations on Global, Biophysically-Realistic Genotype–Phenotype Maps.” <i>Current Opinion in Genetics &#38; Development</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.gde.2026.102483\">https://doi.org/10.1016/j.gde.2026.102483</a>.","ama":"Mascolo E, Körei RE, Herrera-Álvarez S, Guet CC, Crocker J, Tkačik G. Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. <i>Current Opinion in Genetics &#38; Development</i>. 2026;99. doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102483\">10.1016/j.gde.2026.102483</a>","ista":"Mascolo E, Körei RE, Herrera-Álvarez S, Guet CC, Crocker J, Tkačik G. 2026. Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. Current Opinion in Genetics &#38; Development. 99, 102483.","mla":"Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part 1: Simulations on Global, Biophysically-Realistic Genotype–Phenotype Maps.” <i>Current Opinion in Genetics &#38; Development</i>, vol. 99, 102483, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102483\">10.1016/j.gde.2026.102483</a>.","ieee":"E. Mascolo, R. E. Körei, S. Herrera-Álvarez, C. C. Guet, J. Crocker, and G. Tkačik, “Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps,” <i>Current Opinion in Genetics &#38; Development</i>, vol. 99. Elsevier, 2026."},"PlanS_conform":"1","abstract":[{"lang":"eng","text":"Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences that bind transcription factor (TF) proteins to up- or down-regulate target genes. Decades-long efforts yielded TF-DNA interaction models that predict how strongly an individual TF binds arbitrary DNA sequences and how individual binding events on the CRE combine to affect gene expression. These insights can be synthesized into a global, biophysically realistic, and quantitative genotype–phenotype map for gene regulation, a ‘holy grail’ for the application of evolutionary theory. A global map provides a rare opportunity to simulate the long-term evolution of regulatory sequences and pose several fundamental questions: How long does it take to evolve CREs de novo? How many non-trivial regulatory functions exist in sequence space? How connected are they? For which regulatory architecture is CRE evolution most rapid and evolvable? In this article, the first of a two-part series, we briefly review the pertinent modeling and simulation efforts for a unique system that enables close, quantitative, and mechanistic links between biophysics, as well as systems, synthetic, and evolutionary biology."}],"OA_place":"publisher","date_published":"2026-05-09T00:00:00Z","oa":1,"publication":"Current Opinion in Genetics & Development","author":[{"full_name":"Mascolo, Elia","id":"776a6ed0-a053-11f0-8635-80b95e0e0d53","first_name":"Elia","orcid":"0000-0003-2977-7844","last_name":"Mascolo"},{"last_name":"Körei","id":"50FDE43E-AA30-11E9-A72B-8A12E6697425","full_name":"Körei, Reka E","first_name":"Reka E"},{"full_name":"Herrera-Álvarez, Santiago","first_name":"Santiago","last_name":"Herrera-Álvarez"},{"orcid":"0000-0001-6220-2052","last_name":"Guet","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","full_name":"Guet, Calin C","first_name":"Calin C"},{"last_name":"Crocker","first_name":"Justin","full_name":"Crocker, Justin"},{"last_name":"Tkačik","orcid":"0000-0002-6699-1455","first_name":"Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","full_name":"Tkačik, Gašper"}]},{"oa_version":"Published Version","acknowledgement":"We thank Fyodor Kondrashov and Gašper Tkačik for valuable input and guidance in building the model, and Stephen Abedon as well as the two anonymous reviewers for the comments provided on the manuscript.","quality_controlled":"1","publication_status":"published","citation":{"ista":"Wu B, Guet CC. 2026. Responsive lysogeny under nonproductive phage binding. Evolution. 80(6), 1365–1373.","ieee":"B. Wu and C. C. Guet, “Responsive lysogeny under nonproductive phage binding,” <i>Evolution</i>, vol. 80, no. 6. Oxford University Press, pp. 1365–1373, 2026.","mla":"Wu, Bryan, and Calin C. Guet. “Responsive Lysogeny under Nonproductive Phage Binding.” <i>Evolution</i>, vol. 80, no. 6, Oxford University Press, 2026, pp. 1365–73, doi:<a href=\"https://doi.org/10.1093/evolut/qpag061\">10.1093/evolut/qpag061</a>.","apa":"Wu, B., &#38; Guet, C. C. (2026). Responsive lysogeny under nonproductive phage binding. <i>Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/evolut/qpag061\">https://doi.org/10.1093/evolut/qpag061</a>","chicago":"Wu, Bryan, and Calin C Guet. “Responsive Lysogeny under Nonproductive Phage Binding.” <i>Evolution</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/evolut/qpag061\">https://doi.org/10.1093/evolut/qpag061</a>.","ama":"Wu B, Guet CC. Responsive lysogeny under nonproductive phage binding. <i>Evolution</i>. 2026;80(6):1365-1373. doi:<a href=\"https://doi.org/10.1093/evolut/qpag061\">10.1093/evolut/qpag061</a>","short":"B. Wu, C.C. Guet, Evolution 80 (2026) 1365–1373."},"PlanS_conform":"1","abstract":[{"text":"Upon infecting a bacterial cell, temperate phages make a decision between lysis and lysogeny. While research has previously explored how phages sense environmental information to make this choice, most studies have focused on modelling known mechanisms that impact the decision. These mechanisms tell us what environmental information the phage does respond to, but not what it should respond to, as the signals sensed by the phage may serve as proxies for other sources of information. Here, using a mechanism-agnostic population dynamics model, we find that irreversible phage binding to lysogens protects sensitive host cells from infection. This results in lysogens being an additional environmental factor that the phage should sense while making its decision to undergo lysis or lysogeny. Using this model, we derive a responsive lysogeny probability for phages that respond to both cell and lysogen densities optimized towards invading phage-occupied systems, and show that it is more capable of invading and resisting invasion than phage with fixed lysogeny probabilities across different environmental conditions.","lang":"eng"}],"OA_place":"publisher","oa":1,"date_published":"2026-06-01T00:00:00Z","author":[{"last_name":"Wu","id":"3C521EBA-F248-11E8-B48F-1D18A9856A87","full_name":"Wu, Bryan","first_name":"Bryan"},{"first_name":"Calin C","full_name":"Guet, Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet","orcid":"0000-0001-6220-2052"}],"publication":"Evolution","pmid":1,"language":[{"iso":"eng"}],"type":"journal_article","issue":"6","publication_identifier":{"eissn":["1558-5646"],"issn":["0014-3820"]},"volume":80,"OA_type":"hybrid","_id":"21985","related_material":{"link":[{"url":"https://github.com/theguetlab/responsive-lysogeny","relation":"software"}]},"doi":"10.1093/evolut/qpag061","external_id":{"pmid":["41968110"]},"page":"1365-1373","year":"2026","title":"Responsive lysogeny under nonproductive phage binding","article_type":"original","department":[{"_id":"CaGu"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","scopus_import":"1","has_accepted_license":"1","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_id":"22015","date_updated":"2026-06-16T12:45:09Z","date_created":"2026-06-16T12:45:09Z","success":1,"content_type":"application/pdf","access_level":"open_access","file_name":"2026_Evolution_Wu.pdf","relation":"main_file","file_size":2077781,"checksum":"6d0f48566a7a36cb0c469e1968c9cb1c","creator":"dernst"}],"file_date_updated":"2026-06-16T12:45:09Z","month":"06","ddc":["570"],"publisher":"Oxford University Press","date_created":"2026-06-10T07:38:12Z","date_updated":"2026-06-16T12:46:02Z","day":"01","status":"public","intvolume":"        80"},{"oa_version":"Published Version","publication_status":"published","citation":{"ista":"York E, Venkataraman L. 2026. Scanning tunneling microscope-based break-junction technique - A tutorial. ACS Physical Chemistry Au. 6(3), 408–424.","mla":"York, Emma, and Latha Venkataraman. “Scanning Tunneling Microscope-Based Break-Junction Technique - A Tutorial.” <i>ACS Physical Chemistry Au</i>, vol. 6, no. 3, American Chemical Society, 2026, pp. 408–24, doi:<a href=\"https://doi.org/10.1021/acsphyschemau.6c00026\">10.1021/acsphyschemau.6c00026</a>.","ieee":"E. York and L. Venkataraman, “Scanning tunneling microscope-based break-junction technique - A tutorial,” <i>ACS Physical Chemistry Au</i>, vol. 6, no. 3. American Chemical Society, pp. 408–424, 2026.","apa":"York, E., &#38; Venkataraman, L. (2026). Scanning tunneling microscope-based break-junction technique - A tutorial. <i>ACS Physical Chemistry Au</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsphyschemau.6c00026\">https://doi.org/10.1021/acsphyschemau.6c00026</a>","short":"E. York, L. Venkataraman, ACS Physical Chemistry Au 6 (2026) 408–424.","ama":"York E, Venkataraman L. Scanning tunneling microscope-based break-junction technique - A tutorial. <i>ACS Physical Chemistry Au</i>. 2026;6(3):408-424. doi:<a href=\"https://doi.org/10.1021/acsphyschemau.6c00026\">10.1021/acsphyschemau.6c00026</a>","chicago":"York, Emma, and Latha Venkataraman. “Scanning Tunneling Microscope-Based Break-Junction Technique - A Tutorial.” <i>ACS Physical Chemistry Au</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsphyschemau.6c00026\">https://doi.org/10.1021/acsphyschemau.6c00026</a>."},"acknowledgement":"We thank Michael Inkpen, Timothy Su, Masha Kamenetska, and Wanzhuo Shi for comments and Jyotisman Hazarika for data collection. This work was supported in part by the National Science Foundation (NSF-DMR 2241180) and by the Institute of Science and Technology Austria.","quality_controlled":"1","OA_place":"publisher","PlanS_conform":"1","chemrxivid":1,"abstract":[{"lang":"eng","text":"Over the past two decades, molecular electronics has made significant progress toward discovering nanoscale analogues of conventional electronic components, largely enabled by the development of the scanning tunneling microscope-based break-junction (STM-BJ) technique. The STM-BJ technique enables precise and highly reproducible measurement of a molecule’s electronic transport properties, making it a powerful technique to explore physiochemical and electrochemical phenomena that are otherwise difficult to access. It has gained substantial popularity in the past 20 years, with experiments becoming increasingly diverse and sophisticated. Despite the wealth of literature, an accessible, practical guide to performing STM-BJ experiments and interpreting the data is largely absent. This tutorial includes a brief background into the development of STM-BJ measurements, followed by detailed explanations of instrumentation, data collection, statistical analysis, variations on standard experiments, and some troubleshooting methods. It is aimed at researchers looking to begin or improve STM-BJ studies in their laboratories, graduate students and postdoctoral researchers learning the technique, and readers seeking to critically evaluate the growing body of STM-BJ literature."}],"author":[{"last_name":"York","full_name":"York, Emma","id":"08dde91e-8e0a-11f0-9d7d-9e8d80864f16","first_name":"Emma"},{"full_name":"Venkataraman, Latha","id":"9ebb78a5-cc0d-11ee-8322-fae086a32caf","first_name":"Latha","orcid":"0000-0002-6957-6089","last_name":"Venkataraman"}],"publication":"ACS Physical Chemistry Au","oa":1,"date_published":"2026-05-04T00:00:00Z","publication_identifier":{"eissn":["2694-2445"]},"issue":"3","volume":6,"OA_type":"gold","pmid":1,"language":[{"iso":"eng"}],"type":"journal_article","_id":"21986","DOAJ_listed":"1","page":"408-424","year":"2026","doi":"10.1021/acsphyschemau.6c00026","external_id":{"pmid":["42221941"],"chemrxivid":["10.26434/chemrxiv.15000474/v1"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes","department":[{"_id":"LaVe"}],"article_type":"original","title":"Scanning tunneling microscope-based break-junction technique - A tutorial","scopus_import":"1","has_accepted_license":"1","month":"05","file_date_updated":"2026-06-19T06:31:16Z","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"content_type":"application/pdf","success":1,"date_updated":"2026-06-19T06:31:16Z","date_created":"2026-06-19T06:31:16Z","file_id":"22020","relation":"main_file","file_name":"2026_ACSPhysChem_York.pdf","access_level":"open_access","creator":"dernst","checksum":"1dc16bdfb1c1cd3acde802f4350cb42a","file_size":11251172}],"das_tickbox":"1","ddc":["540"],"publisher":"American Chemical Society","day":"04","date_updated":"2026-06-22T06:19:21Z","date_created":"2026-06-10T07:38:41Z","intvolume":"         6","status":"public"},{"scopus_import":"1","month":"06","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","year":"2026","external_id":{"pmid":["40909755"]},"doi":"10.1016/j.xgen.2026.101277","article_processing_charge":"Yes","article_type":"original","title":"Separating direct, indirect, and parent-of-origin genetic effects in the human population","department":[{"_id":"MaRo"}],"acknowledged_ssus":[{"_id":"ScienComp"}],"day":"09","date_updated":"2026-06-19T07:00:47Z","date_created":"2026-06-10T07:39:08Z","project":[{"_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A","grant_number":"PCEGP3_181181","name":"Improving estimation and prediction of common complex disease risk"}],"status":"public","publisher":"Elsevier","abstract":[{"text":"We introduce JODIE, a genetic joint modeling approach that estimates how DNA loci influence human traits by partitioning genetic effects into four components: direct effects (from a child’s alleles), indirect maternal and paternal effects (from parents’ alleles), and parent-of-origin (PofO) effects (dependent on parental transmission of alleles), while uniquely accounting for assortative mating. We analyze 30,000 child-mother-father trios from the Estonian Biobank and the Norwegian Mother, Father, and Child Cohort, focusing on height, body mass index, and childhood educational test scores. We find direct effects to be the largest contributor to trait variation, but combined, indirect parental and PofO effects are similarly substantial. We support our results by within-family genome-wide association testing and identify 276 independently associated DNA regions with a complex interplay between direct, indirect, and PofO effects. By joint modeling, we show that direct, indirect, and PofO effects collectively shape human phenotypic variation across loci genome-wide.","lang":"eng"}],"OA_place":"publisher","author":[{"full_name":"Krätschmer, Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73","first_name":"Ilse","orcid":"0000-0002-5636-9259","last_name":"Krätschmer"},{"last_name":"Hegemann","first_name":"Laura","full_name":"Hegemann, Laura"},{"full_name":"Hofmeister, Robin J.","first_name":"Robin J.","last_name":"Hofmeister"},{"full_name":"Corfield, Elizabeth C.","first_name":"Elizabeth C.","last_name":"Corfield"},{"first_name":"Mahdi","full_name":"Mahmoudi, Mahdi","last_name":"Mahmoudi"},{"first_name":"Olivier","full_name":"Delaneau, Olivier","last_name":"Delaneau"},{"last_name":"Andreassen","full_name":"Andreassen, Ole A.","first_name":"Ole A."},{"last_name":"Campbell","first_name":"Archie","full_name":"Campbell, Archie"},{"last_name":"Hayward","full_name":"Hayward, Caroline","first_name":"Caroline"},{"last_name":"Marioni","full_name":"Marioni, Riccardo E.","first_name":"Riccardo E."},{"first_name":"Eivind","full_name":"Ystrom, Eivind","last_name":"Ystrom"},{"first_name":"Alexandra","full_name":"Havdahl, Alexandra","last_name":"Havdahl"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","full_name":"Robinson, Matthew Richard","first_name":"Matthew Richard","orcid":"0000-0001-8982-8813","last_name":"Robinson"}],"publication":"Cell Genomics","date_published":"2026-06-09T00:00:00Z","oa":1,"oa_version":"Published Version","citation":{"ama":"Krätschmer I, Hegemann L, Hofmeister RJ, et al. Separating direct, indirect, and parent-of-origin genetic effects in the human population. <i>Cell Genomics</i>. doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101277\">10.1016/j.xgen.2026.101277</a>","chicago":"Krätschmer, Ilse, Laura Hegemann, Robin J. Hofmeister, Elizabeth C. Corfield, Mahdi Mahmoudi, Olivier Delaneau, Ole A. Andreassen, et al. “Separating Direct, Indirect, and Parent-of-Origin Genetic Effects in the Human Population.” <i>Cell Genomics</i>. Elsevier, n.d. <a href=\"https://doi.org/10.1016/j.xgen.2026.101277\">https://doi.org/10.1016/j.xgen.2026.101277</a>.","short":"I. Krätschmer, L. Hegemann, R.J. Hofmeister, E.C. Corfield, M. Mahmoudi, O. Delaneau, O.A. Andreassen, A. Campbell, C. Hayward, R.E. Marioni, E. Ystrom, A. Havdahl, M.R. Robinson, Cell Genomics (n.d.).","apa":"Krätschmer, I., Hegemann, L., Hofmeister, R. J., Corfield, E. C., Mahmoudi, M., Delaneau, O., … Robinson, M. R. (n.d.). Separating direct, indirect, and parent-of-origin genetic effects in the human population. <i>Cell Genomics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xgen.2026.101277\">https://doi.org/10.1016/j.xgen.2026.101277</a>","ieee":"I. Krätschmer <i>et al.</i>, “Separating direct, indirect, and parent-of-origin genetic effects in the human population,” <i>Cell Genomics</i>. Elsevier.","mla":"Krätschmer, Ilse, et al. “Separating Direct, Indirect, and Parent-of-Origin Genetic Effects in the Human Population.” <i>Cell Genomics</i>, 101277, Elsevier, doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101277\">10.1016/j.xgen.2026.101277</a>.","ista":"Krätschmer I, Hegemann L, Hofmeister RJ, Corfield EC, Mahmoudi M, Delaneau O, Andreassen OA, Campbell A, Hayward C, Marioni RE, Ystrom E, Havdahl A, Robinson MR. Separating direct, indirect, and parent-of-origin genetic effects in the human population. Cell Genomics., 101277."},"publication_status":"inpress","acknowledgement":"We thank Zoltan Kutalik, Peter Visscher, and members of the Robinson group at ISTA for their comments, which improved this manuscript. This work was funded by an SNSF Eccellenza Grant to M.R.R. (PCEGP3-181181) and by core funding from the Institute of Science and Technology Austria.\r\nThe Norwegian Mother, Father, and Child Cohort Study is supported by the Norwegian Ministry of Health and Care Services and the Ministry of Education and Research. We are grateful to all the participating families in Norway who take part in this on-going cohort study. We thank the Norwegian Institute of Public Health (NIPH) for generating high-quality genomic data. The research is part of the HARVEST collaboration, supported by the Research Council of Norway (#229624). We also thank the NORMENT Center for providing genotype data, funded by the Research Council of Norway (#223273), South East Norway Health Authorities, and Stiftelsen Kristian Gerhard Jebsen, and in collaboration with deCODE Genetics. We further thank the Center for Diabetes Research, the University of Bergen for providing genotype data funded by the ERC AdG project SELECTionPREDISPOSED, Stiftelsen Kristian Gerhard Jebsen, Trond Mohn Foundation, the Research Council of Norway, the Novo Nordisk Foundation, the University of Bergen, and the Western Norway Health Authorities. The MoBa work was performed on the TSD (Tjeneste for Sensitive Data) facilities, owned by the University of Oslo, operated and developed by the TSD service group at the University of Oslo, IT Department (USIT, tsd-drift@usit.uio.no). E.Y. is supported by the European Union (grant numbers 101045526 and 101073237) and the Research Council of Norway (grant numbers 336078, 288083, and 331640).\r\nWe would like to acknowledge the participants and investigators of the Generation Scotland Cohort study. Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Genotyping and methylation typing of the GS:SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” [STRADL] ref. 104036/Z/14/Z).\r\nWe would like to thank and acknowledge the participants and investigators of the Estonian Biobank (EstBB) study. The research was conducted using the Estonian Center of Genomics/Roadmap II funded by the Estonian Research Council (project number TT17).\r\nNorwegian analyses were performed on resources provided by Sigma2 - the National Infrastructure for High-Performance Computing and Data Storage in Norway. Estonian Data analysis was carried out in the High-Performance Computing Center cloud provided by University of Tartu. Analysis of the Generation Scotland data and the summary statistics obtained from the other analyses was conducted at IST Austria and is supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp).","quality_controlled":"1","DOAJ_listed":"1","article_number":"101277","publication_identifier":{"eissn":["2666-979X"]},"OA_type":"gold","pmid":1,"type":"journal_article","language":[{"iso":"eng"}],"_id":"21987","main_file_link":[{"url":"https://doi.org/10.1016/j.xgen.2026.101277","open_access":"1"}]},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","month":"05","scopus_import":"1","has_accepted_license":"1","title":"MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis","department":[{"_id":"GradSch"},{"_id":"JiFr"}],"article_processing_charge":"No","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"doi":"10.1101/2025.10.07.680881","year":"2026","status":"public","project":[{"name":"Cyclic nucleotides as second messengers in plants","grant_number":"101142681","_id":"8f347782-16d5-11f0-9cad-8c19706ee739"},{"_id":"bd76d395-d553-11ed-ba76-f678c14f9033","name":"Peptide receptors for auxin canalization in Arabidopsis","grant_number":"I06123"},{"_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6","grant_number":"P37051","name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors"}],"date_updated":"2026-06-19T07:14:01Z","date_created":"2026-06-13T16:57:07Z","day":"30","ddc":["580"],"oa":1,"date_published":"2026-05-30T00:00:00Z","author":[{"id":"f43371a3-09ff-11eb-8013-bd0c6a2f6de8","full_name":"Ge, Zengxiang","first_name":"Zengxiang","orcid":"0000-0001-9381-3577","last_name":"Ge"},{"last_name":"Koczka","full_name":"Koczka, Lilla","first_name":"Lilla"},{"first_name":"Ewa","full_name":"Mazur, Ewa","last_name":"Mazur"},{"first_name":"Gergely","full_name":"Molnar, Gergely","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87","last_name":"Molnar"},{"id":"60466724-5355-11ee-ae5a-fa55e8f99c3d","full_name":"Vladimirtsev, Dmitrii","first_name":"Dmitrii","last_name":"Vladimirtsev"},{"last_name":"Kassem","first_name":"Nada","full_name":"Kassem, Nada"},{"last_name":"Ait Ikene","id":"6a0bb896-6bad-11f1-9bef-906e9eb76034","full_name":"Ait Ikene, Sara","first_name":"Sara"},{"first_name":"Lukas","id":"7c417475-8972-11ed-ae7b-8b674ca26986","full_name":"Fiedler, Lukas","last_name":"Fiedler"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","first_name":"Jiří","orcid":"0000-0002-8302-7596","last_name":"Friml"}],"publication":"bioRxiv","OA_place":"repository","abstract":[{"text":"Adaptive plant development is orchestrated, among others, by directional, intercellular transport of the phytohormone auxin. Self-organizing development, such as flexible vasculature formation, depends on so-called auxin canalization, manifested by the gradual formation of auxin transport channels through feedback between auxin signalling and transport. Herein, we identify MAKR6 as an important, novel component in this feedback. MAKR6 expression accumulates strongly in vascular cells and is tightly regulated by auxin via the Aux/IAA-ARF-WRKY23 transcriptional network. MAKR6 is required for auxin canalization-dependent processes, including leaf venation, vasculature regeneration, and de novo auxin channel formation from local auxin sources. Mechanistically, MAKR6 interacts with the PIN1 auxin transporter, modulating its trafficking and polarization. MAKR6 also associates with and integrates two key receptor-like kinase complexes involved in canalization, TMK1/4 and the CAMEL-CANAR. Together, our study establishes MAKR6 as a multifaceted regulator that couples transcriptional auxin signalling to PIN1 repolarization and coordinates multiple RLK-mediated signalling pathways during canalization. This provides mechanistic insights into auxin canalization and exemplifies a framework for exploring similar regulatory nodes in other developmental contexts.","lang":"eng"}],"acknowledgement":"We would like to thank Dr. Yvon Jaillais (ENS, Lyon) for sharing MAKR2 materials. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The research in the Friml group leading to these results was funded by the European Research Council (ERC): 101142681 CYNIPS; and the Austrian Science Fund (FWF): I 6123-B and P 37051-B. Ewa Mazur was supported by the National Science Centre (NCN), Poland, under the OPUS call in the WEAVE programme: 2021/43/I/NZ1/01835.","publication_status":"submitted","citation":{"apa":"Ge, Z., Koczka, L., Mazur, E., Molnar, G., Vladimirtsev, D., Kassem, N., … Friml, J. (n.d.). MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.10.07.680881\">https://doi.org/10.1101/2025.10.07.680881</a>","short":"Z. Ge, L. Koczka, E. Mazur, G. Molnar, D. Vladimirtsev, N. Kassem, S. Ait Ikene, L. Fiedler, J. Friml, BioRxiv (n.d.).","ama":"Ge Z, Koczka L, Mazur E, et al. MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>","chicago":"Ge, Zengxiang, Lilla Koczka, Ewa Mazur, Gergely Molnar, Dmitrii Vladimirtsev, Nada Kassem, Sara Ait Ikene, Lukas Fiedler, and Jiří Friml. “MAKR6 Integrates TMK and CAMEL/CANAR Signalling for Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.10.07.680881\">https://doi.org/10.1101/2025.10.07.680881</a>.","ista":"Ge Z, Koczka L, Mazur E, Molnar G, Vladimirtsev D, Kassem N, Ait Ikene S, Fiedler L, Friml J. MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. bioRxiv, <a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>.","ieee":"Z. Ge <i>et al.</i>, “MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis,” <i>bioRxiv</i>. .","mla":"Ge, Zengxiang, et al. “MAKR6 Integrates TMK and CAMEL/CANAR Signalling for Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>."},"oa_version":"Preprint","main_file_link":[{"url":"https://doi.org/10.1101/2025.10.07.680881","open_access":"1"}],"_id":"21994","type":"preprint","language":[{"iso":"eng"}],"OA_type":"green"},{"day":"10","date_created":"2026-06-14T22:01:42Z","date_updated":"2026-06-19T09:58:52Z","intvolume":"      1004","status":"public","ddc":["520"],"publisher":"IOP Publishing","scopus_import":"1","has_accepted_license":"1","file_date_updated":"2026-06-19T09:56:29Z","month":"06","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_name":"2026_AstrophysicalJour_Li.pdf","access_level":"open_access","relation":"main_file","success":1,"content_type":"application/pdf","file_id":"22099","date_updated":"2026-06-19T09:56:29Z","date_created":"2026-06-19T09:56:29Z","checksum":"bb76fbb51f8d2834cb79f19e7932e3bd","creator":"dernst","file_size":3386217}],"year":"2026","doi":"10.3847/1538-4357/ae66fd","external_id":{"arxiv":["2604.10440"]},"article_processing_charge":"Yes","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","department":[{"_id":"YlGo"}],"title":"A path to constraints on common envelope ejection in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries","DOAJ_listed":"1","arxiv":1,"article_number":"31","issue":"1","publication_identifier":{"issn":["0004-637X"],"eissn":["1538-4357"]},"volume":1004,"OA_type":"gold","language":[{"iso":"eng"}],"type":"journal_article","_id":"21997","OA_place":"publisher","abstract":[{"lang":"eng","text":"The massive binary common envelope (CE) phase plays a pivotal role in the formation of close black hole (BH)/neutron star binaries, yet significant uncertainties remain in our understanding of this process. In this study, we aim to constrain the massive binary CE phase by systematically reconstructing three observed BH X-ray binaries (BHXBs): GRO J1655-40, SAX J1819.3-2525, and 4U 1543-47. Through comprehensive binary evolution simulations and parametric supernova modeling, we establish lower limits for the CE efficiency parameters under different energy considerations within the standard energy formalism. Specifically, we derive minimum values for three cases: α0.5U and αU, representing CE efficiencies with half and all of the internal energy contributing to the envelope ejection, respectively, and αH, accounting for the envelope’s enthalpy. Our analysis reveals that the self-consistent formation of these three BHXBs requires CE efficiency parameters satisfying α0.5U ≳ 6.7, αU ≳ 4.2, and αH ≳ 1.7. Notably, we find no viable solutions with CE efficiency values below unity, even when considering the most extreme scenarios, in which the envelope binding energy is significantly reduced through enthalpy inclusion. Our results strongly imply that either additional energy sources are required or the formalism itself must be revised. Furthermore, we quantitatively assess the impact of BH natal kicks on our results. A key finding is that 4U 1543-47’s formation requires substantial natal kicks (≳50 km s−1), as lower kick velocities are incompatible with isolated binary evolution."}],"PlanS_conform":"1","author":[{"full_name":"Li, Zhenwei","first_name":"Zhenwei","last_name":"Li"},{"last_name":"Wei","id":"5dd129bd-0601-11ef-b325-833284687b76","full_name":"Wei, Dandan","first_name":"Dandan"},{"last_name":"Jia","full_name":"Jia, Shi","first_name":"Shi"},{"first_name":"Hailiang","full_name":"Chen, Hailiang","last_name":"Chen"},{"full_name":"Ge, Hongwei","first_name":"Hongwei","last_name":"Ge"},{"last_name":"Chen","full_name":"Chen, Zhuo","first_name":"Zhuo"},{"first_name":"Yangyang","full_name":"Zhang, Yangyang","last_name":"Zhang"},{"last_name":"Chen","first_name":"Xuefei","full_name":"Chen, Xuefei"},{"full_name":"Han, Zhanwen","first_name":"Zhanwen","last_name":"Han"}],"publication":"The Astrophysical Journal","date_published":"2026-06-10T00:00:00Z","oa":1,"oa_version":"Published Version","citation":{"ieee":"Z. Li <i>et al.</i>, “A path to constraints on common envelope ejection in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries,” <i>The Astrophysical Journal</i>, vol. 1004, no. 1. IOP Publishing, 2026.","mla":"Li, Zhenwei, et al. “A Path to Constraints on Common Envelope Ejection in Massive Binaries: Full Evolutionary Reconstruction of Three Black Hole X-Ray Binaries.” <i>The Astrophysical Journal</i>, vol. 1004, no. 1, 31, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/1538-4357/ae66fd\">10.3847/1538-4357/ae66fd</a>.","ista":"Li Z, Wei D, Jia S, Chen H, Ge H, Chen Z, Zhang Y, Chen X, Han Z. 2026. A path to constraints on common envelope ejection in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries. The Astrophysical Journal. 1004(1), 31.","ama":"Li Z, Wei D, Jia S, et al. A path to constraints on common envelope ejection in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries. <i>The Astrophysical Journal</i>. 2026;1004(1). doi:<a href=\"https://doi.org/10.3847/1538-4357/ae66fd\">10.3847/1538-4357/ae66fd</a>","short":"Z. Li, D. Wei, S. Jia, H. Chen, H. Ge, Z. Chen, Y. Zhang, X. Chen, Z. Han, The Astrophysical Journal 1004 (2026).","chicago":"Li, Zhenwei, Dandan Wei, Shi Jia, Hailiang Chen, Hongwei Ge, Zhuo Chen, Yangyang Zhang, Xuefei Chen, and Zhanwen Han. “A Path to Constraints on Common Envelope Ejection in Massive Binaries: Full Evolutionary Reconstruction of Three Black Hole X-Ray Binaries.” <i>The Astrophysical Journal</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/1538-4357/ae66fd\">https://doi.org/10.3847/1538-4357/ae66fd</a>.","apa":"Li, Z., Wei, D., Jia, S., Chen, H., Ge, H., Chen, Z., … Han, Z. (2026). A path to constraints on common envelope ejection in massive binaries: Full evolutionary reconstruction of three Black Hole X-ray binaries. <i>The Astrophysical Journal</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/1538-4357/ae66fd\">https://doi.org/10.3847/1538-4357/ae66fd</a>"},"publication_status":"published","acknowledgement":"We deeply thank the referee for a very careful reading and constructive comments that have led to the improvement of the manuscript. The authors are grateful to Poshak Gandhi for his valuable suggestions and feedback on this work. This work is supported by the Natural Science Foundation of China (grant Nos. 12125303, 12525304, 12288102, 12473034, 12103028, 12333008, 12422305, 12090040/3, 12273105, 11703081, 11422324, 12073070, and 12173081), the CAS Project for Young Scientists in Basic Research (YSBR-148), the Strategic Priority Research Program of the Chinese Academy of Sciences (grant Nos. XDB1160303, XDB1160201, and XDB1160000), the National Key R&D Program of China (grant Nos. 2021YFA1600403 and 2021YFA1600400), the Key Research Program of Frontier Sciences of CAS (No. ZDBS-LY-7005), the “CAS Light of West China”, the Yunnan Revitalization Talent Support Program-Science & Technology Champion Project (No. 202305AB350003) and Young Talent Project, the International Centre of Supernovae (ICESUN), Yunnan Key Laboratory of Supernova Research (Nos. 202302AN360001 and 202201BC070003), Yunnan Fundamental Research Projects (No. 202401AT070139), and the Natural Science Foundation of Henan Province (No. 242300420944). X.C. acknowledges the New Cornerstone Science Foundation through the XPLORER PRIZE. The authors gratefully acknowledge the “PHOENIX Supercomputing Platform” jointly operated by the Binary Population Synthesis Group and the Stellar Astrophysics Group at Yunnan Observatories, Chinese Academy of Sciences.","quality_controlled":"1"},{"abstract":[{"lang":"eng","text":"Little Red Dots (LRDs), among the most enigmatic high-redshift discoveries by JWST, are commonly believed to be powered by accreting supermassive black holes. Here, we explore the possibility that these sources are globular clusters in formation, with rest-frame UV arising from a very young stellar population and rest-frame optical from a short-lived supermassive (>104 M⊙) star. The spectral profiles of LRDs are broadly consistent with this scenario, though the observed temperatures and bolometric luminosities favor emission reprocessed by optically thick continuum-driven winds not fully captured by current models. The LRD z ∼ 5−7 UV luminosity function naturally evolves, under standard evolutionary and mass-loss prescriptions, into a present-day mass function with a turnover at log10(M*/M⊙) = 5.3 and an exponential cutoff at high masses, consistent with local globular cluster populations. We estimate the total present-day number density of LRDs formed across all redshifts to be ≈0.3 Mpc−3, similar within uncertainties to local globular clusters. The observed LRD redshift range matches the age distribution of metal-poor globular clusters, without current LRD counterparts to the metal-rich population. If LRDs are globular clusters in formation, we predict chemical abundance patterns characteristic of multiple stellar populations, including enhanced He and N, and potential Na–O and Al–Mg anticorrelations. These results offer a local perspective to explore this surprisingly abundant population of distant sources, and a potential new window into extreme stellar astrophysics in the early Universe."}],"PlanS_conform":"1","OA_place":"publisher","publication":"The Astrophysical Journal Letters","author":[{"last_name":"Chisholm","first_name":"John","full_name":"Chisholm, John"},{"last_name":"Berg","full_name":"Berg, Danielle A.","first_name":"Danielle A."},{"last_name":"Boylan-Kolchin","first_name":"Michael","full_name":"Boylan-Kolchin, Michael"},{"full_name":"De Graaff, Anna","first_name":"Anna","last_name":"De Graaff"},{"last_name":"Furtak","first_name":"Lukas J.","full_name":"Furtak, Lukas J."},{"first_name":"Vasily","full_name":"Kokorev, Vasily","last_name":"Kokorev"},{"orcid":"0000-0003-2871-127X","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","first_name":"Jorryt J"},{"full_name":"Muñoz, Julian B.","first_name":"Julian B.","last_name":"Muñoz"},{"last_name":"Naidu","full_name":"Naidu, Rohan P.","first_name":"Rohan P."},{"last_name":"Sander","first_name":"Andreas A.C.","full_name":"Sander, Andreas A.C."}],"date_published":"2026-06-10T00:00:00Z","oa":1,"oa_version":"Published Version","citation":{"ama":"Chisholm J, Berg DA, Boylan-Kolchin M, et al. Little Red Dots as globular clusters in formation. <i>The Astrophysical Journal Letters</i>. 2026;1004(1). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae6dae\">10.3847/2041-8213/ae6dae</a>","short":"J. Chisholm, D.A. Berg, M. Boylan-Kolchin, A. De Graaff, L.J. Furtak, V. Kokorev, J.J. Matthee, J.B. Muñoz, R.P. Naidu, A.A.C. Sander, The Astrophysical Journal Letters 1004 (2026).","chicago":"Chisholm, John, Danielle A. Berg, Michael Boylan-Kolchin, Anna De Graaff, Lukas J. Furtak, Vasily Kokorev, Jorryt J Matthee, Julian B. Muñoz, Rohan P. Naidu, and Andreas A.C. Sander. “Little Red Dots as Globular Clusters in Formation.” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2026. <a href=\"https://doi.org/10.3847/2041-8213/ae6dae\">https://doi.org/10.3847/2041-8213/ae6dae</a>.","apa":"Chisholm, J., Berg, D. A., Boylan-Kolchin, M., De Graaff, A., Furtak, L. J., Kokorev, V., … Sander, A. A. C. (2026). Little Red Dots as globular clusters in formation. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae6dae\">https://doi.org/10.3847/2041-8213/ae6dae</a>","ieee":"J. Chisholm <i>et al.</i>, “Little Red Dots as globular clusters in formation,” <i>The Astrophysical Journal Letters</i>, vol. 1004, no. 1. IOP Publishing, 2026.","mla":"Chisholm, John, et al. “Little Red Dots as Globular Clusters in Formation.” <i>The Astrophysical Journal Letters</i>, vol. 1004, no. 1, L4, IOP Publishing, 2026, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae6dae\">10.3847/2041-8213/ae6dae</a>.","ista":"Chisholm J, Berg DA, Boylan-Kolchin M, De Graaff A, Furtak LJ, Kokorev V, Matthee JJ, Muñoz JB, Naidu RP, Sander AAC. 2026. Little Red Dots as globular clusters in formation. The Astrophysical Journal Letters. 1004(1), L4."},"publication_status":"published","quality_controlled":"1","acknowledgement":"We thank the referees for detailed and highly constructive reports that significantly improved the scope and breadth of the manuscript. J.C. thanks Hollis Akins, Volker Bromm, Rui Chaves-Marques, Steve Finkelstein, Karl Gebhardt, Keith Hawkins, Harley Katz, Stellar Offner, Daniel Schaerer, Grace Telford, and Jorick Vink for conversations that improved the Letter. A.d.G. acknowledges support from a Clay Fellowship awarded by the Smithsonian Astrophysical Observatory. M.B.K. acknowledges support from NSF grants AST-2108962 and AST-2408247; NASA grant 80NSSC22K0827; HST-GO-16686, HST-AR-17028, JWST-GO-03788, and JWST-AR-06278 from the Space Telescope Science Institute, which is operated by AURA, Inc., under NASA contract NAS5-26555; and from the Samuel T. and Fern Yanagisawa Regents Professorship in Astronomy at UT Austin. A.A.C.S. acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) in the form of an Emmy Noether Research Group—Project-ID 445674056 (SA4064/1-1, PI Sander). A.A.C.S. further acknowledges support from the Deutsches Zentrum für Luft und Raumfahrt (DLR) grant grants 50 OR 2509 (PI: A.A.C. Sander) and 50 OR 2306 (PI: V. Ramachandran/A.A.C. Sander) as well as from the Federal Ministry of Research, Technology, and Space (BMFTR) and the Baden-Württemberg Ministry of Science as part of the Excellence Strategy of the German Federal and State Governments. This project was cofunded by the European Union (Project 101183150—OCEANS).\r\n\r\nThis work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs 1180, 1181, 1208, 1212, 1213, 1215, 1286, 1345, 1433, 2198, 2561, 2750, 2767, 4106, 4233, 5105, 5224, 6368, and 6585.","DOAJ_listed":"1","arxiv":1,"OA_type":"gold","volume":1004,"issue":"1","publication_identifier":{"issn":["2041-8205"],"eissn":["2041-8213"]},"article_number":"L4","language":[{"iso":"eng"}],"type":"journal_article","_id":"21998","has_accepted_license":"1","scopus_import":"1","month":"06","file_date_updated":"2026-06-19T09:45:21Z","file":[{"success":1,"content_type":"application/pdf","file_id":"22098","date_updated":"2026-06-19T09:45:21Z","date_created":"2026-06-19T09:45:21Z","access_level":"open_access","file_name":"2026_AstrophysicalJourLetters_Chisholm.pdf","relation":"main_file","checksum":"66949af6e620c8ef37de42688829a3e3","creator":"dernst","file_size":919919}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2026","external_id":{"arxiv":["2602.15935"]},"doi":"10.3847/2041-8213/ae6dae","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes","title":"Little Red Dots as globular clusters in formation","department":[{"_id":"JoMa"}],"article_type":"original","day":"10","date_updated":"2026-06-19T09:50:33Z","date_created":"2026-06-14T22:01:42Z","intvolume":"      1004","status":"public","publisher":"IOP Publishing","ddc":["520"]},{"abstract":[{"text":"We consider the standard overlap (math formular) of any bi-orthogonal family of left and right eigenvectors of a large random matrix X with centred i.i.d. entries and we prove that it decays as an inverse second power of the distance between the corresponding eigenvalues. This extends similar results for the complex Gaussian ensemble from Bourgade and Dubach [15], as well as Benaych-Georges and Zeitouni [13], to any i.i.d. matrix ensemble in both symmetry classes. As a main tool, we prove a two-resolvent local law for the Hermitisation of X uniformly in the spectrum with optimal decay rate and optimal dependence on the density near the spectral edge.","lang":"eng"}],"PlanS_conform":"1","OA_place":"publisher","oa":1,"date_published":"2026-01-01T00:00:00Z","author":[{"id":"42198EFA-F248-11E8-B48F-1D18A9856A87","full_name":"Cipolloni, Giorgio","first_name":"Giorgio","orcid":"0000-0002-4901-7992","last_name":"Cipolloni"},{"last_name":"Erdös","orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","full_name":"Erdös, László"},{"last_name":"Xu","orcid":"0000-0003-1559-1205","first_name":"Yuanyuan","full_name":"Xu, Yuanyuan","id":"7902bdb1-a2a4-11eb-a164-c9216f71aea3"}],"publication":"Journal of Functional Analysis","oa_version":"Published Version","quality_controlled":"1","acknowledgement":"Partially supported by ERC Advanced Grant “RMTBeyond” No. 101020331. Partially supported by National Key R&D Program of China No. 2024YFA1013503.","oaworkid":1,"publication_status":"published","citation":{"ista":"Cipolloni G, Erdös L, Xu Y. 2026. Optimal decay of eigenvector overlap for non-Hermitian random matrices. Journal of Functional Analysis. 290(1), 111180.","ieee":"G. Cipolloni, L. Erdös, and Y. Xu, “Optimal decay of eigenvector overlap for non-Hermitian random matrices,” <i>Journal of Functional Analysis</i>, vol. 290, no. 1. Elsevier, 2026.","mla":"Cipolloni, Giorgio, et al. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>, vol. 290, no. 1, 111180, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>.","apa":"Cipolloni, G., Erdös, L., &#38; Xu, Y. (2026). Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>","ama":"Cipolloni G, Erdös L, Xu Y. Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. 2026;290(1). doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>","chicago":"Cipolloni, Giorgio, László Erdös, and Yuanyuan Xu. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>.","short":"G. Cipolloni, L. Erdös, Y. Xu, Journal of Functional Analysis 290 (2026)."},"arxiv":1,"type":"journal_article","language":[{"iso":"eng"}],"article_number":"111180","publication_identifier":{"issn":["0022-1236"]},"issue":"1","volume":290,"OA_type":"hybrid","_id":"20328","scopus_import":"1","has_accepted_license":"1","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"file_size":2503887,"creator":"dernst","checksum":"ee53d5e695f0df11e017c8c9242a2b04","relation":"main_file","file_name":"2026_JourFuncAnalysis_Cipolloni.pdf","access_level":"open_access","date_updated":"2026-01-05T13:05:47Z","date_created":"2026-01-05T13:05:47Z","file_id":"20947","content_type":"application/pdf","success":1}],"month":"01","file_date_updated":"2026-01-05T13:05:47Z","doi":"10.1016/j.jfa.2025.111180","external_id":{"arxiv":["2411.16572"],"isi":["001583178200001"],"oaworkid":["w4413883397"]},"year":"2026","article_type":"original","title":"Optimal decay of eigenvector overlap for non-Hermitian random matrices","department":[{"_id":"LaEr"}],"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","date_created":"2025-09-10T05:46:07Z","date_updated":"2026-06-03T13:12:14Z","day":"01","isi":1,"status":"public","intvolume":"       290","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","grant_number":"101020331","name":"Random matrices beyond Wigner-Dyson-Mehta","call_identifier":"H2020"}],"ec_funded":1,"ddc":["510"],"publisher":"Elsevier"},{"arxiv":1,"language":[{"iso":"eng"}],"type":"journal_article","publication_identifier":{"eissn":["1096-0902"],"issn":["0095-8956"]},"OA_type":"hybrid","volume":176,"_id":"20422","abstract":[{"text":"We show that if n is odd and p>=Clog n/n, then with high probability Hamilton cycles in G(n,p) span its cycle space. More generally, we show this holds for a class of graphs satisfying certain natural pseudorandom properties. The proof is based on a novel idea of parity-switchers, which can be thought of as analogues of absorbers in the context of cycle spaces. As another application of our method, we show that Hamilton cycles in a near-Dirac graph G, that is, a graph G with odd n vertices and minimum degree n/2+C for sufficiently large constant C, span its cycle space.\r\n","lang":"eng"}],"OA_place":"publisher","PlanS_conform":"1","oa":1,"date_published":"2026-01-01T00:00:00Z","author":[{"first_name":"Micha","full_name":"Christoph, Micha","last_name":"Christoph"},{"last_name":"Nenadov","first_name":"Rajko","full_name":"Nenadov, Rajko"},{"last_name":"Petrova","first_name":"Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","full_name":"Petrova, Kalina H"}],"publication":"Journal of Combinatorial Theory Series B","oa_version":"Published Version","quality_controlled":"1","acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Image 1 Part of this research was conducted while the author was at Department of Computer Science, ETH Zürich, Switzerland. This author was supported by grant no. CRSII5 173721 of the Swiss National Science Foundation.","citation":{"chicago":"Christoph, Micha, Rajko Nenadov, and Kalina H Petrova. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>.","ama":"Christoph M, Nenadov R, Petrova KH. The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. 2026;176:254-267. doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>","short":"M. Christoph, R. Nenadov, K.H. Petrova, Journal of Combinatorial Theory Series B 176 (2026) 254–267.","apa":"Christoph, M., Nenadov, R., &#38; Petrova, K. H. (2026). The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>","ieee":"M. Christoph, R. Nenadov, and K. H. Petrova, “The Hamilton space of pseudorandom graphs,” <i>Journal of Combinatorial Theory Series B</i>, vol. 176. Elsevier, pp. 254–267, 2026.","mla":"Christoph, Micha, et al. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>, vol. 176, Elsevier, 2026, pp. 254–67, doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>.","ista":"Christoph M, Nenadov R, Petrova KH. 2026. The Hamilton space of pseudorandom graphs. Journal of Combinatorial Theory Series B. 176, 254–267."},"publication_status":"published","date_created":"2025-10-05T22:01:34Z","date_updated":"2026-01-05T13:29:52Z","day":"01","isi":1,"status":"public","intvolume":"       176","project":[{"call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"ec_funded":1,"ddc":["510"],"publisher":"Elsevier","scopus_import":"1","has_accepted_license":"1","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"success":1,"content_type":"application/pdf","file_id":"20953","date_created":"2026-01-05T13:29:34Z","date_updated":"2026-01-05T13:29:34Z","access_level":"open_access","file_name":"2026_JourCombTheoryB_Christoph.pdf","relation":"main_file","checksum":"60676af4af4b3243ba187e7d65440d99","creator":"dernst","file_size":688924}],"file_date_updated":"2026-01-05T13:29:34Z","month":"01","external_id":{"arxiv":["2402.01447"],"isi":["001585783400001"]},"doi":"10.1016/j.jctb.2025.09.002","page":"254-267","year":"2026","article_type":"original","title":"The Hamilton space of pseudorandom graphs","department":[{"_id":"MaKw"}],"article_processing_charge":"Yes (via OA deal)","tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"}},{"oa_version":"Published Version","citation":{"short":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, M. Saghafian, Discrete and Computational Geometry 75 (2026) 24–47.","chicago":"Biswas, Ranita, Sebastiano Cultrera di Montesano, Ondrej Draganov, Herbert Edelsbrunner, and Morteza Saghafian. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>.","ama":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. 2026;75:24-47. doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>","apa":"Biswas, R., Cultrera di Montesano, S., Draganov, O., Edelsbrunner, H., &#38; Saghafian, M. (2026). On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>","mla":"Biswas, Ranita, et al. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>, vol. 75, Springer Nature, 2026, pp. 24–47, doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>.","ieee":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, and M. Saghafian, “On the size of chromatic Delaunay mosaics,” <i>Discrete and Computational Geometry</i>, vol. 75. Springer Nature, pp. 24–47, 2026.","ista":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. 2026. On the size of chromatic Delaunay mosaics. Discrete and Computational Geometry. 75, 24–47."},"publication_status":"published","quality_controlled":"1","acknowledgement":"The fourth author thanks Boris Aronov for insightful discussions on the size of the overlay of Voronoi tessellations. Open access funding provided by Institute of Science and Technology (IST Austria). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme, grant no. 788183, from the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, Austrian Science Fund (FWF), grant no. I 02979-N35.","abstract":[{"lang":"eng","text":"Given a locally finite set A⊆Rd and a coloring χ:A→{0,1,…,s}, we introduce the chromatic Delaunay mosaic of χ, which is a Delaunay mosaic in Rs+d that represents how points of different colors mingle. Our main results are bounds on the size of the chromatic Delaunay mosaic, in which we assume that d and s are constants. For example, if A is finite with n=#A, and the coloring is random, then the chromatic Delaunay mosaic has O(n⌈d/2⌉) cells in expectation. In contrast, for Delone sets and Poisson point processes in Rd, the expected number of cells within a closed ball is only a constant times the number of points in this ball. Furthermore, in R2 all colorings of a dense set of n points have chromatic Delaunay mosaics of size O(n). This encourages the use of chromatic Delaunay mosaics in applications."}],"PlanS_conform":"1","OA_place":"publisher","author":[{"orcid":"0000-0002-5372-7890","last_name":"Biswas","full_name":"Biswas, Ranita","id":"3C2B033E-F248-11E8-B48F-1D18A9856A87","first_name":"Ranita"},{"orcid":"0000-0001-6249-0832","last_name":"Cultrera di Montesano","id":"34D2A09C-F248-11E8-B48F-1D18A9856A87","full_name":"Cultrera di Montesano, Sebastiano","first_name":"Sebastiano"},{"full_name":"Draganov, Ondrej","id":"2B23F01E-F248-11E8-B48F-1D18A9856A87","first_name":"Ondrej","orcid":"0000-0003-0464-3823","last_name":"Draganov"},{"orcid":"0000-0002-9823-6833","last_name":"Edelsbrunner","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","full_name":"Edelsbrunner, Herbert","first_name":"Herbert"},{"last_name":"Saghafian","full_name":"Saghafian, Morteza","id":"f86f7148-b140-11ec-9577-95435b8df824","first_name":"Morteza"}],"publication":"Discrete and Computational Geometry","oa":1,"date_published":"2026-01-01T00:00:00Z","publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"volume":75,"OA_type":"hybrid","type":"journal_article","language":[{"iso":"eng"}],"_id":"20456","arxiv":1,"related_material":{"record":[{"status":"public","relation":"earlier_version","id":"15090"}]},"page":"24-47","year":"2026","doi":"10.1007/s00454-025-00778-7","external_id":{"arxiv":["2212.03121"],"isi":["001584166900001"]},"tmp":{"short":"CC BY (4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_processing_charge":"Yes (via OA deal)","title":"On the size of chromatic Delaunay mosaics","department":[{"_id":"HeEd"}],"article_type":"original","scopus_import":"1","has_accepted_license":"1","file_date_updated":"2026-01-05T13:21:20Z","month":"01","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file":[{"content_type":"application/pdf","success":1,"date_created":"2026-01-05T13:21:20Z","date_updated":"2026-01-05T13:21:20Z","file_id":"20952","relation":"main_file","file_name":"2026_DiscreteCompGeom_Biswas.pdf","access_level":"open_access","creator":"dernst","checksum":"0addb5c1b78142f9fb453bfa04695400","file_size":570922}],"ec_funded":1,"ddc":["510"],"publisher":"Springer Nature","day":"01","date_created":"2025-10-12T22:01:26Z","date_updated":"2026-01-05T13:21:56Z","intvolume":"        75","project":[{"_id":"266A2E9E-B435-11E9-9278-68D0E5697425","grant_number":"788183","name":"Alpha Shape Theory Extended","call_identifier":"H2020"},{"_id":"268116B8-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Mathematics, Computer Science","grant_number":"Z00342"},{"_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Persistence and stability of geometric complexes","grant_number":"I02979-N35"}],"isi":1,"status":"public"}]
