[{"publisher":"American Physical Society","department":[{"_id":"CaGo"},{"_id":"GradSch"}],"file":[{"content_type":"application/pdf","file_size":2680924,"creator":"dernst","access_level":"open_access","date_created":"2026-03-23T15:53:29Z","relation":"main_file","date_updated":"2026-03-23T15:53:29Z","file_name":"2026_PhysicalReviewResearch_Huebl.pdf","file_id":"21493","checksum":"6d8a68e4a19f8dad5abdf75f72316f3d","success":1}],"citation":{"apa":"Hübl, M., &#38; Goodrich, C. P. (2026). Entropic size control of self-assembled filaments. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/68rs-3qgn\">https://doi.org/10.1103/68rs-3qgn</a>","mla":"Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled Filaments.” <i>Physical Review Research</i>, vol. 8, L012054, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/68rs-3qgn\">10.1103/68rs-3qgn</a>.","ieee":"M. Hübl and C. P. Goodrich, “Entropic size control of self-assembled filaments,” <i>Physical Review Research</i>, vol. 8. American Physical Society, 2026.","ama":"Hübl M, Goodrich CP. Entropic size control of self-assembled filaments. <i>Physical Review Research</i>. 2026;8. doi:<a href=\"https://doi.org/10.1103/68rs-3qgn\">10.1103/68rs-3qgn</a>","ista":"Hübl M, Goodrich CP. 2026. Entropic size control of self-assembled filaments. Physical Review Research. 8, L012054.","chicago":"Hübl, Maximilian, and Carl Peter Goodrich. “Entropic Size Control of Self-Assembled Filaments.” <i>Physical Review Research</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/68rs-3qgn\">https://doi.org/10.1103/68rs-3qgn</a>.","short":"M. Hübl, C.P. Goodrich, Physical Review Research 8 (2026)."},"publication":"Physical Review Research","has_accepted_license":"1","title":"Entropic size control of self-assembled filaments","_id":"21482","OA_place":"publisher","OA_type":"gold","date_updated":"2026-03-23T15:59:11Z","day":"05","status":"public","quality_controlled":"1","doi":"10.1103/68rs-3qgn","publication_identifier":{"eissn":["2643-1564"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","ddc":["530"],"article_processing_charge":"Yes","type":"journal_article","intvolume":"         8","acknowledgement":"We thank Maitane Muñoz-Basagoiti for helpful discussions. The research was supported by the Gesellschaft für Forschungsförderung Niederösterreich under Project No. FTI23-G-011.","oa":1,"language":[{"iso":"eng"}],"date_created":"2026-03-23T14:58:31Z","year":"2026","article_type":"original","date_published":"2026-03-05T00:00:00Z","file_date_updated":"2026-03-23T15:53:29Z","volume":8,"month":"03","abstract":[{"text":"Controlling the size and shape of assembled structures is a fundamental challenge in self-assembly and is highly relevant in material design and biology. Here, we show that specific but promiscuous short-range binding interactions make it possible to economically assemble linear filaments of user-defined length. Our approach leads to independent control over the mean and width of the filament size distribution and allows us to smoothly explore design trade-offs between assembly quality (spread in size) and cost (number of particle species). We employ a simple hierarchical assembly protocol to minimize assembly times and show that multiple stages of hierarchy make it possible to extend our approach to the assembly of higher-dimensional structures. Our work provides a conceptually simple solution to size control that is applicable to a broad range of systems, from DNA nanoparticles to supramolecular polymers and beyond.","lang":"eng"}],"project":[{"_id":"8dd93da8-16d5-11f0-9cad-d2c70200d9a5","grant_number":"FTI23-G-011","name":"Dynamically reconfigurable self-assembly with triangular DNA-origami bricks"}],"DOAJ_listed":"1","author":[{"id":"5eb8629e-15b2-11ec-abd3-e6f3e5e01f32","full_name":"Hübl, Maximilian","last_name":"Hübl","first_name":"Maximilian"},{"first_name":"Carl Peter","last_name":"Goodrich","full_name":"Goodrich, Carl Peter","orcid":"0000-0002-1307-5074","id":"EB352CD2-F68A-11E9-89C5-A432E6697425"}],"article_number":"L012054","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","corr_author":"1"},{"OA_type":"hybrid","date_updated":"2026-06-18T08:31:45Z","day":"11","department":[{"_id":"JiFr"},{"_id":"GradSch"}],"publisher":"Wiley","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1111/nph.71072"}],"citation":{"chicago":"Babic, David, Milan Zupunski, and Jiří Friml. “Imaging and Genetic Toolbox to Study Arabidopsis Embryogenesis.” <i>New Phytologist</i>. Wiley, 2026. <a href=\"https://doi.org/10.1111/nph.71072\">https://doi.org/10.1111/nph.71072</a>.","ista":"Babic D, Zupunski M, Friml J. 2026. Imaging and genetic toolbox to study Arabidopsis embryogenesis. New Phytologist., nph. 71072.","short":"D. Babic, M. Zupunski, J. Friml, New Phytologist (2026).","ieee":"D. Babic, M. Zupunski, and J. Friml, “Imaging and genetic toolbox to study Arabidopsis embryogenesis,” <i>New Phytologist</i>. Wiley, 2026.","mla":"Babic, David, et al. “Imaging and Genetic Toolbox to Study Arabidopsis Embryogenesis.” <i>New Phytologist</i>, nph. 71072, Wiley, 2026, doi:<a href=\"https://doi.org/10.1111/nph.71072\">10.1111/nph.71072</a>.","apa":"Babic, D., Zupunski, M., &#38; Friml, J. (2026). Imaging and genetic toolbox to study Arabidopsis embryogenesis. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.71072\">https://doi.org/10.1111/nph.71072</a>","ama":"Babic D, Zupunski M, Friml J. Imaging and genetic toolbox to study Arabidopsis embryogenesis. <i>New Phytologist</i>. 2026. doi:<a href=\"https://doi.org/10.1111/nph.71072\">10.1111/nph.71072</a>"},"publication":"New Phytologist","has_accepted_license":"1","_id":"21483","title":"Imaging and genetic toolbox to study Arabidopsis embryogenesis","OA_place":"publisher","ddc":["580"],"article_processing_charge":"Yes (via OA deal)","type":"journal_article","status":"public","quality_controlled":"1","publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646X"]},"doi":"10.1111/nph.71072","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","month":"03","abstract":[{"lang":"eng","text":"Embryogenesis in the model plant Arabidopsis thaliana provides a framework for understanding how cell polarity and patterning coordinate with hormonal signalling to establish the plant body plan. Following fertilisation, the zygote divides asymmetrically to generate apical and basal lineages, establishing the apical–basal axis that defines future shoot and root poles. Genetic and molecular analyses of classical mutants including gnom, monopteros (mp), bodenlos (bdl) and topless revealed that localised auxin biosynthesis, directional transport and downstream transcriptional responses are central to apical–basal axis establishment and organ initiation. The main components of this regulation are polarly localised PIN auxin transporters and downstream modules involving MONOPTEROS and WUSCHEL-RELATED HOMEOBOX transcription factors. Advances in microscopy have transformed the study of Arabidopsis embryogenesis: fluorescence-compatible clearing reagents and three-dimensional reconstructions now permit quantitative analyses of cell geometry, division orientation, and cytoskeletal dynamics. Live ovule imaging setups with confocal laser scanning and multiphoton microscopes enable real-time observation of embryo development, while laser-assisted cell ablation can be used to probe cell-to-cell communication and fate plasticity. Together, these methodological breakthroughs position Arabidopsis embryos as a prime model for dissecting the chemical and biophysical cues that shape plant development."}],"acknowledgement":"The authors would like to acknowledge the many colleagues whose valuable contributions to the field could not be included in this review due to space limitations and reference constraints. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","language":[{"iso":"eng"}],"oa":1,"date_created":"2026-03-23T14:59:06Z","year":"2026","article_type":"original","date_published":"2026-03-11T00:00:00Z","author":[{"full_name":"Babic, David","id":"db566d23-f6e0-11ea-865d-e6f270e968e7","first_name":"David","last_name":"Babic"},{"last_name":"Zupunski","first_name":"Milan","id":"f6a21fce-573e-11f0-a150-a8d96aee2539","full_name":"Zupunski, Milan"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","last_name":"Friml"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"pmid":1,"article_number":"nph.71072","publication_status":"epub_ahead","corr_author":"1","external_id":{"pmid":["41808651"]},"PlanS_conform":"1"},{"quality_controlled":"1","doi":"10.1093/genetics/iyag042","publication_identifier":{"issn":["1943-2631"]},"status":"public","related_material":{"link":[{"relation":"software","url":"https://github.com/medical-genomics-group/familyMC"}]},"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"type":"journal_article","article_processing_charge":"Yes (via OA deal)","citation":{"short":"I. Krätschmer, M.R. Robinson, Genetics (2026).","ista":"Krätschmer I, Robinson MR. 2026. A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating. Genetics., iyag042.","chicago":"Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic Model for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative Mating.” <i>Genetics</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/genetics/iyag042\">https://doi.org/10.1093/genetics/iyag042</a>.","ama":"Krätschmer I, Robinson MR. A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating. <i>Genetics</i>. 2026. doi:<a href=\"https://doi.org/10.1093/genetics/iyag042\">10.1093/genetics/iyag042</a>","mla":"Krätschmer, Ilse, and Matthew Richard Robinson. “A Quantitative Genetic Model for Indirect Genetic Effects and Genomic Imprinting under Random and Assortative Mating.” <i>Genetics</i>, iyag042, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/genetics/iyag042\">10.1093/genetics/iyag042</a>.","apa":"Krätschmer, I., &#38; Robinson, M. R. (2026). A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating. <i>Genetics</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/genetics/iyag042\">https://doi.org/10.1093/genetics/iyag042</a>","ieee":"I. Krätschmer and M. R. Robinson, “A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating,” <i>Genetics</i>. Oxford University Press, 2026."},"has_accepted_license":"1","publication":"Genetics","department":[{"_id":"MaRo"}],"publisher":"Oxford University Press","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/genetics/iyag042"}],"OA_place":"publisher","title":"A quantitative genetic model for indirect genetic effects and genomic imprinting under random and assortative mating","_id":"21484","date_updated":"2026-06-18T08:31:14Z","OA_type":"hybrid","day":"12","PlanS_conform":"1","author":[{"last_name":"Krätschmer","first_name":"Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73","orcid":"0000-0002-5636-9259","full_name":"Krätschmer, Ilse"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","full_name":"Robinson, Matthew Richard","orcid":"0000-0001-8982-8813","last_name":"Robinson","first_name":"Matthew Richard"}],"corr_author":"1","external_id":{"pmid":["41677404"]},"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"iyag042","pmid":1,"publication_status":"epub_ahead","language":[{"iso":"eng"}],"acknowledgement":"We thank members of the Medical Genomics group at ISTA for their comments, which improved this manuscript. This work was funded by an SNSF Eccellenza Grant to MRR (PCEGP3-181181), and by core funding from the Institute of Science and Technology Austria.","oa":1,"year":"2026","article_type":"original","date_published":"2026-02-12T00:00:00Z","date_created":"2026-03-23T15:02:54Z","abstract":[{"lang":"eng","text":"An individual's phenotype reflects a complex interplay of the direct effects of their DNA, epigenetic modifications of their DNA induced by their parents, and indirect effects of their parents' DNA. Here, we derive how the genetic variance within a population is changed under the influence of indirect maternal, paternal and parent-of-origin effects under random mating. We also consider indirect effects of a sibling, in particular how the genetic variance is altered when looking at the phenotypic difference between two siblings. The calculations are then extended to include assortative mating (AM), which alters the variance by inducing increased homozygosity and correlations within and across loci. AM likely leads to covariance of parental genetic effects, a measure of the similarity of parents in the indirect effects they have on their children. We propose that this assortment for parental characteristics, where biological parents create similar environments for their children, can create shared parental effects across traits and the appearance of cross-trait AM. Our theory shows how the resemblance among relatives increases under both AM, indirect and parent-of-origin effects. When our model is used to predict correlations among relatives in human height, we find that explaining the patterns observed in real data requires both indirect genetic effects and assortative mating. The degree to which direct, indirect and epigenetic effects shape the phenotypic variance of complex traits remains an open question that requires large-scale family data to be resolved."}],"month":"02"},{"_id":"21485","title":"Adventitious carbon breaks symmetry in oxide contact electrification","OA_place":"publisher","publisher":"Springer Nature","department":[{"_id":"ScWa"},{"_id":"GradSch"},{"_id":"LifeSc"}],"file":[{"success":1,"file_id":"21494","checksum":"dafef9ed575b44be4263e948a47ae056","file_name":"2026_Nature_Grosjean.pdf","date_updated":"2026-03-24T06:57:08Z","relation":"main_file","date_created":"2026-03-24T06:57:08Z","access_level":"open_access","creator":"dernst","content_type":"application/pdf","file_size":12245694}],"citation":{"apa":"Grosjean, G. M., Ostermann, M., Sauer, M., Hahn, M., Pichler, C. M., Fahrnberger, F., … Waitukaitis, S. R. (2026). Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>","mla":"Grosjean, Galien M., et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>, vol. 651, no. 8106, Springer Nature, 2026, pp. 626–31, doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>.","ieee":"G. M. Grosjean <i>et al.</i>, “Adventitious carbon breaks symmetry in oxide contact electrification,” <i>Nature</i>, vol. 651, no. 8106. Springer Nature, pp. 626–631, 2026.","ama":"Grosjean GM, Ostermann M, Sauer M, et al. Adventitious carbon breaks symmetry in oxide contact electrification. <i>Nature</i>. 2026;651(8106):626-631. doi:<a href=\"https://doi.org/10.1038/s41586-025-10088-w\">10.1038/s41586-025-10088-w</a>","ista":"Grosjean GM, Ostermann M, Sauer M, Hahn M, Pichler CM, Fahrnberger F, Pertl F, Balazs D, Link MM, Kim SH, Schrader DL, Blanco A, Gracia F, Mujica N, Waitukaitis SR. 2026. Adventitious carbon breaks symmetry in oxide contact electrification. Nature. 651(8106), 626–631.","chicago":"Grosjean, Galien M, Markus Ostermann, Markus Sauer, Michael Hahn, Christian M. Pichler, Florian Fahrnberger, Felix Pertl, et al. “Adventitious Carbon Breaks Symmetry in Oxide Contact Electrification.” <i>Nature</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41586-025-10088-w\">https://doi.org/10.1038/s41586-025-10088-w</a>.","short":"G.M. Grosjean, M. Ostermann, M. Sauer, M. Hahn, C.M. Pichler, F. Fahrnberger, F. Pertl, D. Balazs, M.M. Link, S.H. Kim, D.L. Schrader, A. Blanco, F. Gracia, N. Mujica, S.R. Waitukaitis, Nature 651 (2026) 626–631."},"publication":"Nature","has_accepted_license":"1","day":"18","OA_type":"hybrid","date_updated":"2026-04-28T12:06:01Z","related_material":{"link":[{"url":"https://ista.ac.at/en/news/colliding-dust-and-the-sparks-of-creation/","relation":"press_release","description":"News on ISTA website"}]},"page":"626-631","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","oa_version":"Published Version","ec_funded":1,"status":"public","quality_controlled":"1","doi":"10.1038/s41586-025-10088-w","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"article_processing_charge":"Yes (via OA deal)","type":"journal_article","ddc":["540"],"date_created":"2026-03-23T15:04:00Z","year":"2026","article_type":"original","file_date_updated":"2026-03-24T06:57:08Z","date_published":"2026-03-18T00:00:00Z","intvolume":"       651","language":[{"iso":"eng"}],"oa":1,"acknowledgement":"This project has received support from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 949120) and from the Marie Skłodowska-Curie programme (grant agreement no. 754411). We acknowledge the state of Lower Austria and the European Regional Development Fund under grant no. WST3-F-542638/004-2021. N.M. acknowledges support from grant Fondecyt 1221597. G.G. is a Serra Húnter fellow. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Miba Machine Shop, Nanofabrication Facility, Scientific Computing facility and Lab Support Facility. We thank the Modic group for the use of the Laue camera, T. Zauner for the photography of the experimental set-up and R. Möller for insightful discussions. Open access funding provided by Institute of Science and Technology (IST Austria).","issue":"8106","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"},{"_id":"ScienComp"},{"_id":"LifeSc"}],"month":"03","abstract":[{"lang":"eng","text":"Insulating oxides are among the most abundant solid materials in the universe1,2,3. Of the many ways in which they influence natural phenomena, perhaps the most consequential is their capacity to transfer electrical charge during contact4,5,6,7,8,9,10—which occurs even between samples of the same oxide—yet the symmetry-breaking parameter that causes this remains unidentified11,12. Here we show that adventitious carbonaceous molecules adsorbed from the environment are the symmetry-breaking factor in same-material oxide contact electrification (CE). We use acoustic levitation to measure charge exchange between a sphere and a plate composed of identical amorphous silicon dioxide (SiO2). Although charging polarity is random for co-prepared samples, we control it with baking or plasma treatment. Observing the charge-exchange relaxation afterwards, we see dynamics over a timescale of hours and connect this directly to the presence of adventitious carbon with time-of-flight mass spectrometry, low-energy ion scattering and infrared spectroscopy. Going further, we confirm that adventitious carbon can even determine charge exchange among different oxides. Our results identify the symmetry-breaking parameter that causes insulating oxides to exchange charge in settings ranging from desert sands4 to volcanic plumes5,6, while simultaneously highlighting an overlooked factor in CE more broadly."}],"volume":651,"project":[{"name":"Tribocharge: a multi-scale approach to an enduring problem in physics","grant_number":"949120","call_identifier":"H2020","_id":"0aa60e99-070f-11eb-9043-a6de6bdc3afa"},{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"PlanS_conform":"1","pmid":1,"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","corr_author":"1","external_id":{"pmid":["41851325"]},"author":[{"id":"0C5FDA4A-9CF6-11E9-8939-FF05E6697425","orcid":"0000-0001-5154-417X","full_name":"Grosjean, Galien M","last_name":"Grosjean","first_name":"Galien M"},{"last_name":"Ostermann","first_name":"Markus","full_name":"Ostermann, Markus"},{"last_name":"Sauer","first_name":"Markus","full_name":"Sauer, Markus"},{"first_name":"Michael","last_name":"Hahn","full_name":"Hahn, Michael"},{"last_name":"Pichler","first_name":"Christian M.","full_name":"Pichler, Christian M."},{"full_name":"Fahrnberger, Florian","last_name":"Fahrnberger","first_name":"Florian"},{"full_name":"Pertl, Felix","orcid":"0000-0003-0463-5794","id":"6313aec0-15b2-11ec-abd3-ed67d16139af","first_name":"Felix","last_name":"Pertl"},{"last_name":"Balazs","first_name":"Daniel","id":"302BADF6-85FC-11EA-9E3B-B9493DDC885E","full_name":"Balazs, Daniel","orcid":"0000-0001-7597-043X"},{"first_name":"Mason M.","last_name":"Link","full_name":"Link, Mason M."},{"last_name":"Kim","first_name":"Seong H.","full_name":"Kim, Seong H."},{"full_name":"Schrader, Devin L.","last_name":"Schrader","first_name":"Devin L."},{"first_name":"Adriana","last_name":"Blanco","full_name":"Blanco, Adriana"},{"first_name":"Francisco","last_name":"Gracia","full_name":"Gracia, Francisco"},{"full_name":"Mujica, Nicolás","first_name":"Nicolás","last_name":"Mujica"},{"last_name":"Waitukaitis","first_name":"Scott R","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","full_name":"Waitukaitis, Scott R","orcid":"0000-0002-2299-3176"}]},{"type":"journal_article","article_processing_charge":"Yes","ddc":["570"],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","publication_identifier":{"eissn":["2056-3744"]},"doi":"10.1093/evlett/qrag003","status":"public","day":"12","date_updated":"2026-03-24T07:14:08Z","OA_type":"gold","OA_place":"publisher","title":"Causes and consequences of sex-chromosome turnovers in Diptera","_id":"21486","citation":{"chicago":"Layana Franco, Lorena Alexandra, Melissa A Toups, and Beatriz Vicoso. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” <i>Evolution Letters</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/evlett/qrag003\">https://doi.org/10.1093/evlett/qrag003</a>.","ista":"Layana Franco LA, Toups MA, Vicoso B. 2026. Causes and consequences of sex-chromosome turnovers in Diptera. Evolution Letters., qrag003.","short":"L.A. Layana Franco, M.A. Toups, B. Vicoso, Evolution Letters (2026).","ieee":"L. A. Layana Franco, M. A. Toups, and B. Vicoso, “Causes and consequences of sex-chromosome turnovers in Diptera,” <i>Evolution Letters</i>. Oxford University Press, 2026.","apa":"Layana Franco, L. A., Toups, M. A., &#38; Vicoso, B. (2026). Causes and consequences of sex-chromosome turnovers in Diptera. <i>Evolution Letters</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/evlett/qrag003\">https://doi.org/10.1093/evlett/qrag003</a>","mla":"Layana Franco, Lorena Alexandra, et al. “Causes and Consequences of Sex-Chromosome Turnovers in Diptera.” <i>Evolution Letters</i>, qrag003, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/evlett/qrag003\">10.1093/evlett/qrag003</a>.","ama":"Layana Franco LA, Toups MA, Vicoso B. Causes and consequences of sex-chromosome turnovers in Diptera. <i>Evolution Letters</i>. 2026. doi:<a href=\"https://doi.org/10.1093/evlett/qrag003\">10.1093/evlett/qrag003</a>"},"has_accepted_license":"1","publication":"Evolution Letters","publisher":"Oxford University Press","department":[{"_id":"BeVi"},{"_id":"GradSch"}],"main_file_link":[{"url":"https://doi.org/10.1093/evlett/qrag003","open_access":"1"}],"corr_author":"1","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"qrag003","publication_status":"epub_ahead","author":[{"full_name":"Layana Franco, Lorena Alexandra","orcid":"0000-0002-1253-6297","id":"02814589-eb8f-11eb-b029-a70074f3f18f","first_name":"Lorena Alexandra","last_name":"Layana Franco"},{"last_name":"Toups","first_name":"Melissa A","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A"},{"first_name":"Beatriz","last_name":"Vicoso","full_name":"Vicoso, Beatriz","orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87"}],"DOAJ_listed":"1","project":[{"name":"Sex chromosomes in evolution and development","grant_number":"PAT 8748323","_id":"8ed82125-16d5-11f0-9cad-fbcae312235b"}],"abstract":[{"text":"Sex-chromosome systems are highly variable across animals, but how they transition from one to another is not well understood. Diptera have undergone multiple sex-chromosome turnovers and expansions while maintaining their general chromosomal content, which makes them an ideal clade to study such transitions. We analyzed more than 100 dipteran whole-genome assemblies and identified 4 new lineages that underwent sex-chromosome turnover (in addition to the 5 previously reported). We find that the majority of turnovers happened in the group Schizophora, which tend to have fewer genes on Muller element F (the chromosome homologous to the ancestral insect X chromosome) than lower dipterans, a factor previously hypothesized to facilitate turnover. Most derived X chromosomes have higher GC content than autosomes, consistent with a high prevalence of male achiasmy in Diptera. In addition, an excess of gene movement out of the X is detected for most of these new X chromosomes, and many of these moved genes have high testis expression in Drosophila, suggesting that out-of-X gene movement contributes to the long-term demasculinization of X chromosomes.","lang":"eng"}],"month":"03","article_type":"original","year":"2026","date_published":"2026-03-12T00:00:00Z","date_created":"2026-03-23T15:05:42Z","language":[{"iso":"eng"}],"acknowledgement":"This work was supported by a grant from the Austrian Science Fund (FWF, grant number PAT 8748323) to B.V. We thank the Vicoso group for their feedback on an early version of the manuscript. We are grateful to Kamil Jaron and Julia Gries for helpful discussions and for sharing their unpublished work. Computational resources and support were provided by the Scientific Computing Unit at ISTA.","oa":1},{"DOAJ_listed":"1","project":[{"name":"Prix Lopez-Loretta 2019 - Marco Mondelli","_id":"059876FA-7A3F-11EA-A408-12923DDC885E"},{"grant_number":"101161364","name":"Inference in High Dimensions: Light-speed Algorithms and Information Limits","_id":"911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf"},{"name":"Improving estimation and prediction of common complex disease risk","grant_number":"PCEGP3_181181","_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A"}],"author":[{"first_name":"Al","last_name":"Depope","full_name":"Depope, Al","id":"0b77531d-dbcd-11ea-9d1d-a8eee0bf3830"},{"first_name":"Jakub","last_name":"Bajzik","full_name":"Bajzik, Jakub","id":"b995e25b-8c4b-11ed-a6d8-f71b7bcd6122"},{"orcid":"0000-0002-3242-7020","full_name":"Mondelli, Marco","id":"27EB676C-8706-11E9-9510-7717E6697425","first_name":"Marco","last_name":"Mondelli"},{"orcid":"0000-0001-8982-8813","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","first_name":"Matthew Richard","last_name":"Robinson"}],"corr_author":"1","article_number":"101162","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"publication_status":"epub_ahead","acknowledgement":"We thank Malgorzata Borczyk for creating the gene burden scores. We thank Robin Beaumont, Amedeo Roberto Esposito, Gareth Hawkes, Philip Schniter, Matthew Stephens, Pragya Sur, Peter Visscher, Michael Weedon, and Harry Wright for providing valuable suggestions and comments on earlier versions of the work. This project was funded by a Lopez-Loreta Prize to M.M., an SNSF Eccellenza Grant to M.R.R. (PCEGP3-181181), an ERC Starting Grant to M.M. (INF2, project number 101161364), and core funding from ISTA. High-performance computing was supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp). We would like to acknowledge the participants and investigators of the UK Biobank study. We gratefully acknowledge the All of Us participants for their contributions, without whom this research would not have been possible. We also thank the National Institutes of Health All of Us Research Program for making available the participant data (and/or samples and/or cohort) examined in this study.","language":[{"iso":"eng"}],"oa":1,"article_type":"original","year":"2026","date_published":"2026-02-18T00:00:00Z","date_created":"2026-03-23T15:10:03Z","abstract":[{"text":"Human height is a model for the genetic analysis of complex traits, and recent studies suggest the presence of thousands of common genetic variant associations and hundreds of low-frequency/rare variants. Here, we develop a new algorithmic paradigm based on approximate message passing (genomic vector approximate message passing [gVAMP]) for identifying DNA sequence variants associated with complex traits and common diseases in large-scale whole-genome sequencing (WGS) data. We show that gVAMP accurately localizes associations to variants with the correct frequency and position in the DNA, outperforming existing fine-mapping methods in selecting the appropriate genetic variants within WGS data. We then apply gVAMP to jointly model the relationship of tens of millions of WGS variants with human height in hundreds of thousands of UK Biobank individuals. We identify 59 rare variants and gene burden scores alongside many hundreds of DNA regions containing common variant associations and show that understanding the genetic basis of complex traits will require the joint analysis of hundreds of millions of variables measured on millions of people. The polygenic risk scores obtained from gVAMP have high accuracy (including a prediction accuracy of ∼46% for human height) and outperform current methods for downstream tasks such as mixed linear model association testing across 13 UK Biobank traits. In conclusion, gVAMP offers a scalable foundation for a wider range of analyses in WGS data.","lang":"eng"}],"month":"02","quality_controlled":"1","publication_identifier":{"eissn":["2666-979X"]},"doi":"10.1016/j.xgen.2026.101162","status":"public","related_material":{"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/big-data-and-human-height/"}]},"oa_version":"Published Version","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","ddc":["000","570"],"type":"journal_article","article_processing_charge":"Yes","citation":{"short":"A. Depope, J. Bajzik, M. Mondelli, M.R. Robinson, Cell Genomics (2026).","chicago":"Depope, Al, Jakub Bajzik, Marco Mondelli, and Matthew Richard Robinson. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” <i>Cell Genomics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">https://doi.org/10.1016/j.xgen.2026.101162</a>.","ista":"Depope A, Bajzik J, Mondelli M, Robinson MR. 2026. Joint modeling of whole-genome sequencing data for human height via approximate message passing. Cell Genomics., 101162.","ama":"Depope A, Bajzik J, Mondelli M, Robinson MR. Joint modeling of whole-genome sequencing data for human height via approximate message passing. <i>Cell Genomics</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">10.1016/j.xgen.2026.101162</a>","ieee":"A. Depope, J. Bajzik, M. Mondelli, and M. R. Robinson, “Joint modeling of whole-genome sequencing data for human height via approximate message passing,” <i>Cell Genomics</i>. Elsevier, 2026.","apa":"Depope, A., Bajzik, J., Mondelli, M., &#38; Robinson, M. R. (2026). Joint modeling of whole-genome sequencing data for human height via approximate message passing. <i>Cell Genomics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">https://doi.org/10.1016/j.xgen.2026.101162</a>","mla":"Depope, Al, et al. “Joint Modeling of Whole-Genome Sequencing Data for Human Height via Approximate Message Passing.” <i>Cell Genomics</i>, 101162, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.xgen.2026.101162\">10.1016/j.xgen.2026.101162</a>."},"publication":"Cell Genomics","has_accepted_license":"1","publisher":"Elsevier","department":[{"_id":"MaMo"},{"_id":"MaRo"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.xgen.2026.101162","open_access":"1"}],"OA_place":"publisher","_id":"21488","title":"Joint modeling of whole-genome sequencing data for human height via approximate message passing","date_updated":"2026-04-28T12:08:37Z","OA_type":"gold","day":"18"},{"author":[{"last_name":"Elkner","first_name":"Mischa M","id":"477faa59-080d-11ed-979a-c693ab7638ab","full_name":"Elkner, Mischa M"}],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"epub_ahead","corr_author":"1","external_id":{"arxiv":["2411.16270"]},"project":[{"grant_number":"P35847","name":"Geometry of the tip of the global nilpotent cone","_id":"34b2c9cb-11ca-11ed-8bc3-a50ba74ca4a3"}],"month":"03","abstract":[{"text":"We study Kirillov algebras attached to minuscule highest weight representations of semisimple Lie algebras. They can be viewed as equivariant cohomology algebras of partial flag varieties. Real structures on the varieties then induce involutions of these algebras. We describe how these involutions act on the spectra of minuscule Kirillov algebras, and model the fixed points via the equivariant cohomology of real partial flag varieties. We then use this model to characterise freeness of the fixed point coordinate ring over the appropriate base. As an application, we recover a q = -1 phenomenon of Stembridge in the minuscule case by geometric means.","lang":"eng"}],"language":[{"iso":"eng"}],"acknowledgement":"I would like to thank Tamás Hausel for introducing me to this area of mathematics and for his constant guidance. I would also like to thank Jakub Löwit and Miguel González for fruitful discussions and many helpful comments on this paper. This work was done during the author’s PhD studies at the Institute of Science and Technology Austria (ISTA). It was funded by the Austrian Science Fund (FWF) 10.55776/P35847. Open access funding provided by Institute of Science and Technology (IST Austria). ","oa":1,"date_created":"2026-03-23T15:10:43Z","year":"2026","date_published":"2026-03-14T00:00:00Z","ddc":["510"],"article_processing_charge":"Yes (via OA deal)","arxiv":1,"type":"journal_article","status":"public","quality_controlled":"1","doi":"10.1007/s00031-026-09958-y","publication_identifier":{"eissn":["1531-586X"],"issn":["1083-4362"]},"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-03-24T08:26:10Z","day":"14","publisher":"Springer Nature","department":[{"_id":"TaHa"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s00031-026-09958-y"}],"citation":{"chicago":"Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by Real Structures.” <i>Transformation Groups</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00031-026-09958-y\">https://doi.org/10.1007/s00031-026-09958-y</a>.","ista":"Elkner MM. 2026. On involutions of minuscule Kirillov algebras induced by real structures. Transformation Groups.","short":"M.M. Elkner, Transformation Groups (2026).","ieee":"M. M. Elkner, “On involutions of minuscule Kirillov algebras induced by real structures,” <i>Transformation Groups</i>. Springer Nature, 2026.","mla":"Elkner, Mischa M. “On Involutions of Minuscule Kirillov Algebras Induced by Real Structures.” <i>Transformation Groups</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s00031-026-09958-y\">10.1007/s00031-026-09958-y</a>.","apa":"Elkner, M. M. (2026). On involutions of minuscule Kirillov algebras induced by real structures. <i>Transformation Groups</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00031-026-09958-y\">https://doi.org/10.1007/s00031-026-09958-y</a>","ama":"Elkner MM. On involutions of minuscule Kirillov algebras induced by real structures. <i>Transformation Groups</i>. 2026. doi:<a href=\"https://doi.org/10.1007/s00031-026-09958-y\">10.1007/s00031-026-09958-y</a>"},"publication":"Transformation Groups","has_accepted_license":"1","title":"On involutions of minuscule Kirillov algebras induced by real structures","_id":"21489"},{"PlanS_conform":"1","project":[{"_id":"8f347782-16d5-11f0-9cad-8c19706ee739","name":"Cyclic nucleotides as second messengers in plants","grant_number":"101142681"},{"name":"Identification of a novel regulator in auxin canalization","grant_number":"E271","_id":"bd906599-d553-11ed-ba76-abf8547645d7"}],"corr_author":"1","external_id":{"pmid":["41831441"]},"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"pmid":1,"publication_status":"published","author":[{"last_name":"Li","first_name":"Mingyue","id":"01f96916-0235-11eb-9379-a323192643b7","full_name":"Li, Mingyue"},{"full_name":"Rydza, Nikola","last_name":"Rydza","first_name":"Nikola"},{"last_name":"Mazur","first_name":"Ewa","full_name":"Mazur, Ewa"},{"id":"34F1AF46-F248-11E8-B48F-1D18A9856A87","full_name":"Molnar, Gergely","last_name":"Molnar","first_name":"Gergely"},{"full_name":"Nodzyński, Tomasz","first_name":"Tomasz","last_name":"Nodzyński"},{"full_name":"Friml, Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jiří","last_name":"Friml"}],"article_type":"original","year":"2026","date_published":"2026-03-23T00:00:00Z","file_date_updated":"2026-03-24T08:34:37Z","date_created":"2026-03-23T15:11:16Z","acknowledgement":"We thank Dr. Z. Ge (ISTA) for providing vectors for the CRISPR-Cas9 system, Dr. Armel Nicolas and Dr. Bella Bruszel for phosphoproteomic analysis, Prof. Michael Wrzaczek (Czech Academy of Sciences, Czechia) for valuable suggestions, and Prof. Maciek Adamowski (University of Gdańsk) for technical assistance. We also acknowledge the support of the Mass Spectrometry and Proteomics Facility, the Imaging & Optics Facility, and the Lab Support Facility at the Institute of Science and Technology Austria. This research was supported by the Scientific Service Units (SSU) of ISTA, utilizing resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The work conducted by the Friml group was funded by the European Research Council (ERC) under grant agreement no. 101142681 (CYNIPS) and by the Austrian Science Fund (FWF) under project ESP271. We acknowledge the core facility CELLIM supported by MEYS CR (LM2023050 Czech-BioImaging) and the Plant Sciences Core Facility of CEITEC Masaryk University. E.M. received support from the National Science Centre (NCN), Poland, through the OPUS call within the Weave programme (grant no. 2021/43/I/NZ1/01835). T.N. received support from TowArds Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of the ERDF Programme Johannes Amos Comenius.","language":[{"iso":"eng"}],"issue":"6","oa":1,"intvolume":"        36","abstract":[{"lang":"eng","text":"Auxin canalization is a self-organizing process that governs the flexible formation of vasculature by reinforcing the formation of auxin transport channels. A key prerequisite is the feedback between auxin signaling and directional auxin transport, mediated by PIN transporters. Despite the developmental importance of canalization, the molecular components linking auxin perception to the regulation of PIN auxin transporters remain poorly understood. Here, we identify TOW, a novel and essential component of auxin canalization that links intracellular auxin signaling with cell surface auxin perception. TOW is regulated downstream of TIR1/AFB-Aux/IAA-WRKY23 transcriptional auxin signaling. tow mutants exhibit defects in regeneration and de novo vasculature formation, along with impaired formation of polarized, PIN-expressing auxin channels. At the subcellular level, these mutants display disrupted auxin-induced PIN polarization and altered PIN endocytic trafficking dynamics. TOW localizes predominantly to the plasma membrane, where it interacts with receptor-like kinases involved in auxin canalization, including the TMK1 auxin co-receptor and the CAMEL-CANAR complex. TOW promotes PIN interaction with these kinases and stabilizes PINs at the cell surface. Together, our findings identify TOW as a molecular link between intracellular and cell surface auxin signaling mechanisms that converge on PIN trafficking and polarity, providing new insights into how auxin signaling regulates directional auxin transport for the self-organizing formation of vasculature during flexible plant development."}],"acknowledged_ssus":[{"_id":"MassSpec"},{"_id":"Bio"},{"_id":"LifeSc"}],"month":"03","volume":36,"page":"1468-1480.e6","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","doi":"10.1016/j.cub.2026.02.023","publication_identifier":{"issn":["0960-9822"]},"status":"public","type":"journal_article","article_processing_charge":"Yes (via OA deal)","ddc":["580"],"OA_place":"publisher","_id":"21490","title":"Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization","citation":{"ama":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. 2026;36(6):1468-1480.e6. doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>","ieee":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, and J. Friml, “Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization,” <i>Current Biology</i>, vol. 36, no. 6. Elsevier, p. 1468–1480.e6, 2026.","mla":"Li, Mingyue, et al. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>, vol. 36, no. 6, Elsevier, 2026, p. 1468–1480.e6, doi:<a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">10.1016/j.cub.2026.02.023</a>.","apa":"Li, M., Rydza, N., Mazur, E., Molnar, G., Nodzyński, T., &#38; Friml, J. (2026). Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>","short":"M. Li, N. Rydza, E. Mazur, G. Molnar, T. Nodzyński, J. Friml, Current Biology 36 (2026) 1468–1480.e6.","chicago":"Li, Mingyue, Nikola Rydza, Ewa Mazur, Gergely Molnar, Tomasz Nodzyński, and Jiří Friml. “Receptor-like-Kinase-Interacting Protein TOW Stabilizes PIN Transporters for Auxin Canalization.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2026.02.023\">https://doi.org/10.1016/j.cub.2026.02.023</a>.","ista":"Li M, Rydza N, Mazur E, Molnar G, Nodzyński T, Friml J. 2026. Receptor-like-kinase-interacting protein TOW stabilizes PIN transporters for auxin canalization. Current Biology. 36(6), 1468–1480.e6."},"publication":"Current Biology","has_accepted_license":"1","publisher":"Elsevier","department":[{"_id":"JiFr"}],"file":[{"creator":"dernst","content_type":"application/pdf","file_size":12986894,"relation":"main_file","date_created":"2026-03-24T08:34:37Z","access_level":"open_access","file_name":"2026_CurrentBiology_Li.pdf","date_updated":"2026-03-24T08:34:37Z","success":1,"checksum":"fe6c41fdab58a55df5f2a5860c02acdc","file_id":"21496"}],"day":"23","date_updated":"2026-03-24T08:36:40Z","OA_type":"hybrid"},{"abstract":[{"text":"Kinetically constrained models were originally introduced to capture slow relaxation in glassy systems, where dynamics are hindered by local constraints instead of energy barriers. Their quantum counterparts have recently drawn attention for exhibiting highly degenerate eigenstates at zero energy—known as zero modes—stemming from chiral symmetry. Yet, the structure and implications of these zero modes remain poorly understood. In this work, we focus on the properties of the zero mode subspace in quantum kinetically constrained models with a U(1) particle-conservation symmetry. We use the U(1) East, which lacks inversion symmetry, and the inversion-symmetric U(1) East-West models to illustrate our two main results. First, we observe that the simultaneous presence of constraints and chiral symmetry generally leads to a parametric increase in the number of zero modes due to the fragmentation of the many-body\r\nHilbert space into disconnected sectors. Second, we generalize the concept of compact localized states from single-particle physics and introduce the notion of collective bound states, a special kind of nonergodic eigenstates that are robust to enlarging the system size. We formulate sufficient criteria for their existence, arguing that the degenerate zero mode subspace plays a central role, and demonstrate bound states in both example models and in a two-dimensional model, the U(1) North-East, and in the pairflip model, a system without particle conservation. Our results motivate a systematic study of bound states and their relation to ergodicity breaking, transport, and other properties of quantum kinetically constrained\r\nmodels. ","lang":"eng"}],"month":"03","volume":7,"year":"2026","article_type":"original","date_published":"2026-03-13T00:00:00Z","file_date_updated":"2026-03-30T06:08:07Z","date_created":"2026-03-28T14:57:56Z","language":[{"iso":"eng"}],"acknowledgement":"The authors acknowledge useful discussions with Berislav Buca. This work was supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. 850899). M.L. acknowledges support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC-2111—390814868. This research was supported in part by grant NSF PHY-2309135 to the Kavli Institute for Theoretical Physics (KITP).","oa":1,"intvolume":"         7","corr_author":"1","external_id":{"arxiv":["2504.17627"]},"article_number":"010352","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","author":[{"first_name":"Eulalia","last_name":"Nicolau Jimenez","full_name":"Nicolau Jimenez, Eulalia","id":"04b4791c-8fd7-11ee-a7df-be2fdc569c48"},{"first_name":"Marko","last_name":"Ljubotina","full_name":"Ljubotina, Marko","orcid":"0000-0003-0038-7068","id":"F75EE9BE-5C90-11EA-905D-16643DDC885E"},{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","full_name":"Serbyn, Maksym","orcid":"0000-0002-2399-5827","last_name":"Serbyn","first_name":"Maksym"}],"PlanS_conform":"1","DOAJ_listed":"1","project":[{"call_identifier":"H2020","grant_number":"850899","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E"}],"day":"13","date_updated":"2026-03-30T06:09:28Z","OA_type":"gold","OA_place":"publisher","_id":"21501","title":"Fragmentation, zero modes, and collective bound states in constrained models","citation":{"chicago":"Nicolau Jimenez, Eulalia, Marko Ljubotina, and Maksym Serbyn. “Fragmentation, Zero Modes, and Collective Bound States in Constrained Models.” <i>PRX Quantum</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/sl79-1xgb\">https://doi.org/10.1103/sl79-1xgb</a>.","ista":"Nicolau Jimenez E, Ljubotina M, Serbyn M. 2026. Fragmentation, zero modes, and collective bound states in constrained models. PRX Quantum. 7, 010352.","short":"E. Nicolau Jimenez, M. Ljubotina, M. Serbyn, PRX Quantum 7 (2026).","ieee":"E. Nicolau Jimenez, M. Ljubotina, and M. Serbyn, “Fragmentation, zero modes, and collective bound states in constrained models,” <i>PRX Quantum</i>, vol. 7. American Physical Society, 2026.","apa":"Nicolau Jimenez, E., Ljubotina, M., &#38; Serbyn, M. (2026). Fragmentation, zero modes, and collective bound states in constrained models. <i>PRX Quantum</i>. American Physical Society. <a href=\"https://doi.org/10.1103/sl79-1xgb\">https://doi.org/10.1103/sl79-1xgb</a>","mla":"Nicolau Jimenez, Eulalia, et al. “Fragmentation, Zero Modes, and Collective Bound States in Constrained Models.” <i>PRX Quantum</i>, vol. 7, 010352, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/sl79-1xgb\">10.1103/sl79-1xgb</a>.","ama":"Nicolau Jimenez E, Ljubotina M, Serbyn M. Fragmentation, zero modes, and collective bound states in constrained models. <i>PRX Quantum</i>. 2026;7. doi:<a href=\"https://doi.org/10.1103/sl79-1xgb\">10.1103/sl79-1xgb</a>"},"has_accepted_license":"1","publication":"PRX Quantum","publisher":"American Physical Society","department":[{"_id":"MaSe"}],"file":[{"content_type":"application/pdf","file_size":1848724,"creator":"dernst","access_level":"open_access","date_created":"2026-03-30T06:08:07Z","relation":"main_file","date_updated":"2026-03-30T06:08:07Z","file_name":"2026_PRXQuantum_Nicolau.pdf","checksum":"d155ffa9e1a8275702149165f4bf963c","file_id":"21505","success":1}],"type":"journal_article","arxiv":1,"article_processing_charge":"Yes","ddc":["530"],"scopus_import":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","publication_identifier":{"eissn":["2691-3399"]},"doi":"10.1103/sl79-1xgb","status":"public","ec_funded":1},{"day":"17","date_updated":"2026-06-18T08:32:22Z","OA_type":"gold","OA_place":"publisher","title":"Distribution and functional significance of rodent cerebellar glycogen","_id":"21502","citation":{"mla":"Akther, Sonam, et al. “Distribution and Functional Significance of Rodent Cerebellar Glycogen.” <i>IScience</i>, vol. 29, no. 4, 115192, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.isci.2026.115192\">10.1016/j.isci.2026.115192</a>.","apa":"Akther, S., Lee, A. B., Konno, A., Asiminas, A., Vittani, M., Mishima, T., … Hirase, H. (2026). Distribution and functional significance of rodent cerebellar glycogen. <i>IScience</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.isci.2026.115192\">https://doi.org/10.1016/j.isci.2026.115192</a>","ieee":"S. Akther <i>et al.</i>, “Distribution and functional significance of rodent cerebellar glycogen,” <i>iScience</i>, vol. 29, no. 4. Elsevier, 2026.","ama":"Akther S, Lee AB, Konno A, et al. Distribution and functional significance of rodent cerebellar glycogen. <i>iScience</i>. 2026;29(4). doi:<a href=\"https://doi.org/10.1016/j.isci.2026.115192\">10.1016/j.isci.2026.115192</a>","ista":"Akther S, Lee AB, Konno A, Asiminas A, Vittani M, Mishima T, Hirai H, Meehan CF, Duran J, Guinovart J, Ashida H, Morita T, Baba O, Shigemoto R, Nedergaard M, Hirase H. 2026. Distribution and functional significance of rodent cerebellar glycogen. iScience. 29(4), 115192.","chicago":"Akther, Sonam, Ashley Bomin Lee, Ayumu Konno, Antonis Asiminas, Marta Vittani, Tsuneko Mishima, Hirokazu Hirai, et al. “Distribution and Functional Significance of Rodent Cerebellar Glycogen.” <i>IScience</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.isci.2026.115192\">https://doi.org/10.1016/j.isci.2026.115192</a>.","short":"S. Akther, A.B. Lee, A. Konno, A. Asiminas, M. Vittani, T. Mishima, H. Hirai, C.F. Meehan, J. Duran, J. Guinovart, H. Ashida, T. Morita, O. Baba, R. Shigemoto, M. Nedergaard, H. Hirase, IScience 29 (2026)."},"publication":"iScience","department":[{"_id":"RySh"}],"publisher":"Elsevier","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.isci.2026.115192"}],"type":"journal_article","article_processing_charge":"Yes","ddc":["570"],"oa_version":"Published Version","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","doi":"10.1016/j.isci.2026.115192","publication_identifier":{"eissn":["2589-0042"]},"status":"public","abstract":[{"lang":"eng","text":"The mammalian brain stores glucose, the main circulating energy substrate, as glycogen. In rodents, the cerebellum contains relatively high glycogen levels, yet its cellular and subcellular distribution remains poorly defined. Using monoclonal antibodies against glycogen, we examined its distribution in the mouse cerebellar cortex. Glycogen was predominantly localized to Bergmann glia (BG) processes in the molecular layer and was also detected in Purkinje cells (PCs), the principal cerebellar neurons. To assess the functional significance of cerebellar glycogen, we analyzed behavior in mice lacking glycogen synthase 1 (Gys1) in BG or PCs using a floxed Gys1 line. Gys1 deficiency in either PCs or GFAP-positive cells reduced anxiety-like behavior, whereas combined deletion caused PC degeneration and ataxia. These findings reveal a critical role for glycogen metabolism in both astrocytes and neurons in cerebellar function."}],"month":"03","volume":29,"year":"2026","article_type":"original","date_published":"2026-03-17T00:00:00Z","date_created":"2026-03-29T22:07:07Z","issue":"4","acknowledgement":"This work was supported by the Novo Nordisk Foundation (NNFOC0058058, H. Hirase), the Danmarks Frie Forskningsfond (0134-00107B and 5283-00069A, H.Hirase), the Lundbeck Foundation, Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research (KAKENHI) program (22K06454/24H01221, A.K.; 23K27482, H.Hirai), the Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) (JP21dm0207111, H. Hirai), AMED Brain/MINDS 2.0 (JP23wm0625001 and JP24wm0625103, H. Hirai), and grants from the Spanish Ministerio de Ciencia e Innovación (MCIU/FEDER/AEI) (PID2020-118699 GB-100, J.D.) and the Fundación Ramón Areces (J.D.). Sonam Akther has been supported by the RIKEN IPA fellowship. We are thankful to Dr. Yuki Oe for his support in the initial stage of this study and to Dan Xue for his help with the graphical abstract. We thank Dr. Pia Weikop for providing CTN research infrastructure. The authors declare no competing financial interests.","oa":1,"language":[{"iso":"eng"}],"intvolume":"        29","external_id":{"pmid":["41890976"]},"article_number":"115192","pmid":1,"publication_status":"epub_ahead","author":[{"first_name":"Sonam","last_name":"Akther","full_name":"Akther, Sonam"},{"last_name":"Lee","first_name":"Ashley Bomin","full_name":"Lee, Ashley Bomin"},{"last_name":"Konno","first_name":"Ayumu","full_name":"Konno, Ayumu"},{"full_name":"Asiminas, Antonis","first_name":"Antonis","last_name":"Asiminas"},{"full_name":"Vittani, Marta","first_name":"Marta","last_name":"Vittani"},{"full_name":"Mishima, Tsuneko","first_name":"Tsuneko","last_name":"Mishima"},{"full_name":"Hirai, Hirokazu","last_name":"Hirai","first_name":"Hirokazu"},{"full_name":"Meehan, Claire Francesca","first_name":"Claire Francesca","last_name":"Meehan"},{"full_name":"Duran, Jordi","first_name":"Jordi","last_name":"Duran"},{"last_name":"Guinovart","first_name":"Joan","full_name":"Guinovart, Joan"},{"last_name":"Ashida","first_name":"Hitoshi","full_name":"Ashida, Hitoshi"},{"full_name":"Morita, Tsuyoshi","last_name":"Morita","first_name":"Tsuyoshi"},{"full_name":"Baba, Otto","first_name":"Otto","last_name":"Baba"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi"},{"last_name":"Nedergaard","first_name":"Maiken","full_name":"Nedergaard, Maiken"},{"last_name":"Hirase","first_name":"Hajime","full_name":"Hirase, Hajime"}],"DOAJ_listed":"1"},{"author":[{"full_name":"Hajto, Jacek","last_name":"Hajto","first_name":"Jacek"},{"first_name":"Marcin","last_name":"Piechota","full_name":"Piechota, Marcin"},{"last_name":"Krätschmer","first_name":"Ilse","id":"30d4014e-7753-11eb-b44b-db6d61112e73","orcid":"0000-0002-5636-9259","full_name":"Krätschmer, Ilse"},{"last_name":"Konowalska","first_name":"Paula","full_name":"Konowalska, Paula"},{"last_name":"Boyle","first_name":"Gabriel E.","full_name":"Boyle, Gabriel E."},{"first_name":"Douglas M.","last_name":"Fowler","full_name":"Fowler, Douglas M."},{"last_name":"Borczyk","first_name":"Malgorzata","full_name":"Borczyk, Malgorzata"},{"first_name":"Michal","last_name":"Korostynski","full_name":"Korostynski, Michal"}],"publication_status":"published","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","short":"CC BY-NC-ND (4.0)"},"pmid":1,"article_number":"8","external_id":{"pmid":["41803106"]},"volume":26,"month":"03","abstract":[{"text":"Currently, pharmacogenetics relies on partially annotated star alleles, leaving novel variants and complex haplotypes uninterpretable. Computational scoring frameworks could overcome these limitations. Here, we comprehensively evaluated the ability of existing (CADD, FATHMM-XF, PROVEAN, MutationAssessor, SIFT, PhyloP100, APF, APF2) and novel (PharmGScore and PharmMLScore) variant effect predictors to assess pharmacogenetic alleles in multiple scenarios. Altogether we analyzed 541 PharmVar alleles, high‑throughput CYP2C9 and CYP2C19 mutational maps, and 200 642 UK Biobank exomes linked with health records containing antidepressant treatment outcomes. Many evaluated tools, especially ensemble frameworks, matched or exceeded star allele classifications (ROC‑AUC up to 0.85 for allele definitions, 0.95 in vitro; TPR up to 0.99 for exomes) and accurately predicted severe antidepressant adverse events for carriers of deleterious variants in CYP2C19 (OR 1.20–1.35). Our findings show that computational predictors deliver star allele accuracy while overcoming their limitations. With additional validation, computational tools could enhance clinical decision frameworks by enabling continuous scoring, incorporating previously unknown variants, and providing genome-wide applicability.","lang":"eng"}],"intvolume":"        26","issue":"2","oa":1,"language":[{"iso":"eng"}],"acknowledgement":"This research has been conducted using the UK Biobank Resource under Application Number 62979. We are grateful to the UK Biobank and all its voluntary participants. This work used data provided by patients and collected by the NHS as part of their care and support.\r\n\r\nThis study was funded by the National Science Center, Poland: PRELUDIUM BIS-3 grant no. 2021/43/O/NZ7/01187 (development and benchmarking of variant scores) and SONATINA 5 grant 2021/40/C/NZ2/00218 (UKB analyses). Additional support came from the statutory funds of the Maj Institute of Pharmacology PAS. We gratefully acknowledge Poland’s high-performance Infrastructure PLGrid ACK Cyfronet AGH, for providing computer facilities and support within computational grant no PLG/2022/015861. DMF and GEB were funded by NIH grants NIH R35GM152106 and UM1HG011969.","date_created":"2026-03-29T22:07:08Z","file_date_updated":"2026-03-30T07:04:08Z","date_published":"2026-03-09T00:00:00Z","article_type":"original","year":"2026","ddc":["570"],"article_processing_charge":"Yes (in subscription journal)","type":"journal_article","status":"public","publication_identifier":{"issn":[" 1470-269X"],"eissn":["1473-1150"]},"doi":"10.1038/s41397-026-00399-0","quality_controlled":"1","scopus_import":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","date_updated":"2026-03-30T07:10:50Z","day":"09","file":[{"relation":"main_file","date_created":"2026-03-30T07:04:08Z","access_level":"open_access","creator":"dernst","file_size":2618963,"content_type":"application/pdf","success":1,"file_id":"21506","checksum":"2fd3d7e48b779ac24245f6c35449b89a","file_name":"2026_PharmacogenomicsJour_Hajto.pdf","date_updated":"2026-03-30T07:04:08Z"}],"department":[{"_id":"MaRo"}],"publisher":"Springer Nature","has_accepted_license":"1","publication":"Pharmacogenomics Journal","citation":{"chicago":"Hajto, Jacek, Marcin Piechota, Ilse Krätschmer, Paula Konowalska, Gabriel E. Boyle, Douglas M. Fowler, Malgorzata Borczyk, and Michal Korostynski. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>.","ista":"Hajto J, Piechota M, Krätschmer I, Konowalska P, Boyle GE, Fowler DM, Borczyk M, Korostynski M. 2026. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. Pharmacogenomics Journal. 26(2), 8.","short":"J. Hajto, M. Piechota, I. Krätschmer, P. Konowalska, G.E. Boyle, D.M. Fowler, M. Borczyk, M. Korostynski, Pharmacogenomics Journal 26 (2026).","ieee":"J. Hajto <i>et al.</i>, “Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants,” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2. Springer Nature, 2026.","mla":"Hajto, Jacek, et al. “Computational Variant Predictors for Pharmacogenomics: From Evaluation of Single Alleles to Assessment of Adverse Drug Reactions to Antidepressants.” <i>Pharmacogenomics Journal</i>, vol. 26, no. 2, 8, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>.","apa":"Hajto, J., Piechota, M., Krätschmer, I., Konowalska, P., Boyle, G. E., Fowler, D. M., … Korostynski, M. (2026). Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41397-026-00399-0\">https://doi.org/10.1038/s41397-026-00399-0</a>","ama":"Hajto J, Piechota M, Krätschmer I, et al. Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants. <i>Pharmacogenomics Journal</i>. 2026;26(2). doi:<a href=\"https://doi.org/10.1038/s41397-026-00399-0\">10.1038/s41397-026-00399-0</a>"},"title":"Computational variant predictors for pharmacogenomics: From evaluation of single alleles to assessment of adverse drug reactions to antidepressants","_id":"21503","OA_place":"publisher"},{"date_created":"2026-03-29T22:07:08Z","date_published":"2026-03-14T00:00:00Z","article_type":"original","year":"2026","acknowledgement":"This work has been written within the activities of GNCS and GNFM groups of INdAM (Italian\r\nNational Institute of High Mathematics). G.B. has been funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 101034413. P.G. has been funded by the European Union - NextGenerationEU, in the framework of the GRINSGrowing Resilient, INclusive and Sustainable (GRINS PE00000018).","oa":1,"language":[{"iso":"eng"}],"month":"03","abstract":[{"text":"Selecting an appropriate divergence measure is a critical aspect of machine learning, as it directly impacts model performance. Among the most widely used, we find the Kullback–Leibler (KL) divergence, originally introduced in kinetic theory as a measure of relative entropy between probability distributions. Just as in machine learning, the ability to quantify the proximity of probability distributions plays a central role in kinetic theory. In this paper, we present a comparative review of divergence measures rooted in kinetic theory, highlighting their theoretical foundations and exploring their potential applications in machine learning and artificial intelligence.","lang":"eng"}],"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program"}],"publication_status":"epub_ahead","external_id":{"arxiv":["2507.11387"]},"author":[{"full_name":"Auricchio, Gennaro","last_name":"Auricchio","first_name":"Gennaro"},{"id":"63ff57e8-1fbb-11ee-88f2-f558ffc59cf1","full_name":"Brigati, Giovanni","last_name":"Brigati","first_name":"Giovanni"},{"full_name":"Giudici, Paolo","first_name":"Paolo","last_name":"Giudici"},{"full_name":"Toscani, Giuseppe","last_name":"Toscani","first_name":"Giuseppe"}],"_id":"21504","title":"From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties","OA_place":"repository","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2507.11387"}],"department":[{"_id":"JaMa"}],"publisher":"World Scientific Publishing","publication":"Mathematical Models and Methods in Applied Sciences","citation":{"short":"G. Auricchio, G. Brigati, P. Giudici, G. Toscani, Mathematical Models and Methods in Applied Sciences (2026).","chicago":"Auricchio, Gennaro, Giovanni Brigati, Paolo Giudici, and Giuseppe Toscani. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>.","ista":"Auricchio G, Brigati G, Giudici P, Toscani G. 2026. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. Mathematical Models and Methods in Applied Sciences.","ama":"Auricchio G, Brigati G, Giudici P, Toscani G. From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. 2026. doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>","ieee":"G. Auricchio, G. Brigati, P. Giudici, and G. Toscani, “From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties,” <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing, 2026.","mla":"Auricchio, Gennaro, et al. “From Kinetic Theory to AI: A Rediscovery of High-Dimensional Divergences and Their Properties.” <i>Mathematical Models and Methods in Applied Sciences</i>, World Scientific Publishing, 2026, doi:<a href=\"https://doi.org/10.1142/S0218202526410010\">10.1142/S0218202526410010</a>.","apa":"Auricchio, G., Brigati, G., Giudici, P., &#38; Toscani, G. (2026). From kinetic theory to AI: A rediscovery of high-dimensional divergences and their properties. <i>Mathematical Models and Methods in Applied Sciences</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0218202526410010\">https://doi.org/10.1142/S0218202526410010</a>"},"day":"14","OA_type":"green","date_updated":"2026-03-30T06:56:35Z","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","status":"public","ec_funded":1,"doi":"10.1142/S0218202526410010","publication_identifier":{"eissn":["1793-6314"],"issn":["0218-2025"]},"quality_controlled":"1","arxiv":1,"article_processing_charge":"No","type":"journal_article"},{"ddc":["570"],"type":"journal_article","article_processing_charge":"Yes (in subscription journal)","doi":"10.1016/j.molcel.2026.01.021","publication_identifier":{"issn":["1097-2765"]},"quality_controlled":"1","status":"public","oa_version":"Published Version","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"625-639.e8","date_updated":"2026-03-30T12:09:08Z","OA_type":"hybrid","day":"19","publication":"Molecular Cell","has_accepted_license":"1","citation":{"ieee":"J. Weiss <i>et al.</i>, “The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2,” <i>Molecular Cell</i>, vol. 86, no. 4. Elsevier, p. 625–639.e8, 2026.","mla":"Weiss, Joscha, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>, vol. 86, no. 4, Elsevier, 2026, p. 625–639.e8, doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>.","apa":"Weiss, J., Vecchia, L., Domjan, D., Cavadini, S., Sabantsev, A., Kempf, G., … Thomä, N. H. (2026). The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>","ama":"Weiss J, Vecchia L, Domjan D, et al. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. <i>Molecular Cell</i>. 2026;86(4):625-639.e8. doi:<a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">10.1016/j.molcel.2026.01.021</a>","chicago":"Weiss, Joscha, Luca Vecchia, David Domjan, Simone Cavadini, Anton Sabantsev, Georg Kempf, Ganesh R. Pathare, et al. “The Human BAF Chromatin Remodeler Processes Nucleosomes Bound by Pioneer Transcription Factors OCT4–SOX2.” <i>Molecular Cell</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.molcel.2026.01.021\">https://doi.org/10.1016/j.molcel.2026.01.021</a>.","ista":"Weiss J, Vecchia L, Domjan D, Cavadini S, Sabantsev A, Kempf G, Pathare GR, Brackmann K, Michael AK, Kater L, Hietter-Pfeiffer E, Haddawi M, Kuber UP, Mühlhäusser S, Grand RS, Stadler MB, Deindl S, Thomä NH. 2026. The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2. Molecular Cell. 86(4), 625–639.e8.","short":"J. Weiss, L. Vecchia, D. Domjan, S. Cavadini, A. Sabantsev, G. Kempf, G.R. Pathare, K. Brackmann, A.K. Michael, L. Kater, E. Hietter-Pfeiffer, M. Haddawi, U.P. Kuber, S. Mühlhäusser, R.S. Grand, M.B. Stadler, S. Deindl, N.H. Thomä, Molecular Cell 86 (2026) 625–639.e8."},"file":[{"file_size":9786677,"content_type":"application/pdf","creator":"dernst","access_level":"open_access","date_created":"2026-03-30T12:04:38Z","relation":"main_file","date_updated":"2026-03-30T12:04:38Z","file_name":"2026_MolecularCell_Weiss.pdf","checksum":"e16a7315b64a706184b177ea1621523c","file_id":"21510","success":1}],"publisher":"Elsevier","department":[{"_id":"AlMi"}],"OA_place":"publisher","title":"The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2","_id":"21509","author":[{"full_name":"Weiss, Joscha","last_name":"Weiss","first_name":"Joscha"},{"full_name":"Vecchia, Luca","first_name":"Luca","last_name":"Vecchia"},{"full_name":"Domjan, David","first_name":"David","last_name":"Domjan"},{"full_name":"Cavadini, Simone","first_name":"Simone","last_name":"Cavadini"},{"full_name":"Sabantsev, Anton","last_name":"Sabantsev","first_name":"Anton"},{"last_name":"Kempf","first_name":"Georg","full_name":"Kempf, Georg"},{"full_name":"Pathare, Ganesh R.","first_name":"Ganesh R.","last_name":"Pathare"},{"first_name":"Klaus","last_name":"Brackmann","full_name":"Brackmann, Klaus"},{"full_name":"Michael, Alicia","orcid":"0000-0002-6080-839X","id":"6437c950-2a03-11ee-914d-d6476dd7b75c","first_name":"Alicia","last_name":"Michael"},{"last_name":"Kater","first_name":"Lukas","full_name":"Kater, Lukas"},{"last_name":"Hietter-Pfeiffer","first_name":"Eric","full_name":"Hietter-Pfeiffer, Eric"},{"last_name":"Haddawi","first_name":"Mina","full_name":"Haddawi, Mina"},{"first_name":"Urja P.","last_name":"Kuber","full_name":"Kuber, Urja P."},{"last_name":"Mühlhäusser","first_name":"Sandra","full_name":"Mühlhäusser, Sandra"},{"full_name":"Grand, Ralph S.","first_name":"Ralph S.","last_name":"Grand"},{"first_name":"Michael B.","last_name":"Stadler","full_name":"Stadler, Michael B."},{"first_name":"Sebastian","last_name":"Deindl","full_name":"Deindl, Sebastian"},{"first_name":"Nicolas H.","last_name":"Thomä","full_name":"Thomä, Nicolas H."}],"external_id":{"pmid":["41679301"]},"publication_status":"published","pmid":1,"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"PlanS_conform":"1","volume":86,"abstract":[{"text":"Chromatin remodeling complexes mobilize nucleosomes and promote transcription factor (TF) binding. Using ensemble and single-molecule assays combined with cryo-electron microscopy (cryo-EM), we studied the interaction between pioneer TFs OCT4–SOX2 and the human BRG1/BRM-associated factor (BAF) complex on nucleosomes. BAF engages TF-bound substrates in two orientations, placing OCT4–SOX2 at either the remodeler ENTRY or EXIT site. At the ENTRY site, OCT4–SOX2 initially coexists with BAF without structural interference. However, continued DNA translocation is expected to cause collisions with bound TFs, which can trigger remodeling direction reversals or may induce TF dissociation. To accommodate TFs at the EXIT site, BAF undergoes structural rearrangements, and ensemble assays reveal a nucleosome subpopulation translocating away from TF-binding sites. Moreover, single-molecule experiments show that nucleosome-bound BAF frequently changes remodeling direction, and we identify an ADP-bound remodeler conformation as a potential intermediate. Together, these findings reveal key aspects of the conformational dynamics and remodeling outcomes underlying BAF processing of TF-bound nucleosomes.","lang":"eng"}],"month":"02","oa":1,"issue":"4","language":[{"iso":"eng"}],"acknowledgement":"We thank D. Hess, V. Iesmantavicius, and J. Seebacher (FMI Proteomics and Protein Analysis Facility) for mass spectrometry support; S. Smallwood, K. Shimada, D. Klein, and M. Schütz-Stoffregen for technical assistance; J. Côté and C. Lachance for critical discussions; and members of the Thomä lab for helpful feedback. Support for this work was provided to N.H.T. by the European Research Council under the European Union’s Horizon 2020 research program (NucEM, no. 884331), the Novartis Research Foundation, the Swiss National Science Foundation (SNF 31003A_179541, 310030_214852, and Sinergia CRSII5_186230), and the Swiss Cancer Research (KFS-4980-02-2020 and KFS-5933-08-2023). S.D. was supported by the European Research Council (DONUTS, no. 101092623), the Knut and Alice Wallenberg Foundation (2024.0012), the Cancerfonden (25 4453 Pj), and the Swedish Research Council (VR 03255). A.K.M. was supported by a Human Frontier Science Program Long-Term Fellowship, and L.V. was supported by an EMBO fellowship (ALTF 549-2021).","intvolume":"        86","date_published":"2026-02-19T00:00:00Z","file_date_updated":"2026-03-30T12:04:38Z","article_type":"original","year":"2026","date_created":"2026-03-30T11:58:48Z"},{"publication_status":"published","external_id":{"arxiv":["2601.09830"]},"author":[{"last_name":"Chen","first_name":"Joshua","full_name":"Chen, Joshua"},{"full_name":"Vaidya, Sachin","last_name":"Vaidya","first_name":"Sachin"},{"last_name":"Pajovic","first_name":"Simo","full_name":"Pajovic, Simo"},{"full_name":"Choi, Seou","last_name":"Choi","first_name":"Seou"},{"first_name":"William","last_name":"Michaels","full_name":"Michaels, William"},{"full_name":"Martin-Monier, Louis","last_name":"Martin-Monier","first_name":"Louis"},{"last_name":"Hu","first_name":"Juejun","full_name":"Hu, Juejun"},{"full_name":"Cogswell, Carol","last_name":"Cogswell","first_name":"Carol"},{"last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"date_created":"2026-03-30T12:22:47Z","article_type":"original","year":"2026","date_published":"2026-03-01T00:00:00Z","intvolume":"        13","language":[{"iso":"eng"}],"oa":1,"issue":"7","month":"03","abstract":[{"lang":"eng","text":"Recent research in nanophotonics for scintillation-based imaging has demonstrated promising improvements in scintillator performance. In parallel, advances in nanophotonics have enabled wavefront control through metasurfaces, a capability that has transformed fields such as microscopy by allowing tailored control of optical propagation. This naturally raises the following question, which we address in this Perspective: can wavefront-control strategies be leveraged to improve scintillation-based imaging? To answer this question, we explore nanophotonic- and metasurface-enabled wavefront control in scintillators to mitigate image blurring arising from their intrinsically diffuse light emission. While depth-of-field extension in scintillation faces fundamental limitations absent in microscopy, this approach reveals promising avenues, including stacked scintillators, selective spatial-frequency enhancement, and X-ray energy-dependent imaging. These results clarify the key distinctions in adapting wavefront engineering to scintillation and its potential to enable tailored detection strategies."}],"volume":13,"page":"1757–1766","oa_version":"Preprint","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","quality_controlled":"1","doi":"10.1021/acsphotonics.5c03124","publication_identifier":{"eissn":["2330-4022"]},"article_processing_charge":"No","arxiv":1,"type":"journal_article","extern":"1","title":"Wavefront engineering for scintillation-based imaging","_id":"21532","OA_place":"repository","publisher":"American Chemical Society","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2601.09830"}],"citation":{"ama":"Chen J, Vaidya S, Pajovic S, et al. Wavefront engineering for scintillation-based imaging. <i>ACS Photonics</i>. 2026;13(7):1757–1766. doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">10.1021/acsphotonics.5c03124</a>","ieee":"J. Chen <i>et al.</i>, “Wavefront engineering for scintillation-based imaging,” <i>ACS Photonics</i>, vol. 13, no. 7. American Chemical Society, pp. 1757–1766, 2026.","mla":"Chen, Joshua, et al. “Wavefront Engineering for Scintillation-Based Imaging.” <i>ACS Photonics</i>, vol. 13, no. 7, American Chemical Society, 2026, pp. 1757–1766, doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">10.1021/acsphotonics.5c03124</a>.","apa":"Chen, J., Vaidya, S., Pajovic, S., Choi, S., Michaels, W., Martin-Monier, L., … Soljačić, M. (2026). Wavefront engineering for scintillation-based imaging. <i>ACS Photonics</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">https://doi.org/10.1021/acsphotonics.5c03124</a>","short":"J. Chen, S. Vaidya, S. Pajovic, S. Choi, W. Michaels, L. Martin-Monier, J. Hu, C. Cogswell, C. Roques-Carmes, M. Soljačić, ACS Photonics 13 (2026) 1757–1766.","chicago":"Chen, Joshua, Sachin Vaidya, Simo Pajovic, Seou Choi, William Michaels, Louis Martin-Monier, Juejun Hu, Carol Cogswell, Charles Roques-Carmes, and Marin Soljačić. “Wavefront Engineering for Scintillation-Based Imaging.” <i>ACS Photonics</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsphotonics.5c03124\">https://doi.org/10.1021/acsphotonics.5c03124</a>.","ista":"Chen J, Vaidya S, Pajovic S, Choi S, Michaels W, Martin-Monier L, Hu J, Cogswell C, Roques-Carmes C, Soljačić M. 2026. Wavefront engineering for scintillation-based imaging. ACS Photonics. 13(7), 1757–1766."},"publication":"ACS Photonics","day":"01","OA_type":"green","date_updated":"2026-05-05T07:53:27Z"},{"status":"public","doi":"10.1038/s41377-025-02166-5","publication_identifier":{"eissn":["2047-7538"]},"quality_controlled":"1","scopus_import":"1","oa_version":"Published Version","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","ddc":["530"],"article_processing_charge":"No","type":"journal_article","extern":"1","main_file_link":[{"url":"https://doi.org/10.1038/s41377-025-02166-5","open_access":"1"}],"publisher":"Springer Nature","publication":"Light: Science & Applications","citation":{"ista":"Salamin Y, Yang G, Mills B, Grossi Fonseca A, Roques-Carmes C, Yang Q, Beroz J, Kooi SE, de Miguel Comella M, Mak K, Vaidya S, Oran D, Swain C, Sun Y, Maayani S, Sloan J, Amin Elfadil Elawad A, Lopez JJ, Boyden ES, Soljačić M. 2026. Three-dimensional nanophotonics with spatially modulated optical properties. Light: Science &#38; Applications. 15, 145.","chicago":"Salamin, Yannick, Gaojie Yang, Brian Mills, André Grossi Fonseca, Charles Roques-Carmes, Quansan Yang, Justin Beroz, et al. “Three-Dimensional Nanophotonics with Spatially Modulated Optical Properties.” <i>Light: Science &#38; Applications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41377-025-02166-5\">https://doi.org/10.1038/s41377-025-02166-5</a>.","short":"Y. Salamin, G. Yang, B. Mills, A. Grossi Fonseca, C. Roques-Carmes, Q. Yang, J. Beroz, S.E. Kooi, M. de Miguel Comella, K. Mak, S. Vaidya, D. Oran, C. Swain, Y. Sun, S. Maayani, J. Sloan, A. Amin Elfadil Elawad, J.J. Lopez, E.S. Boyden, M. Soljačić, Light: Science &#38; Applications 15 (2026).","mla":"Salamin, Yannick, et al. “Three-Dimensional Nanophotonics with Spatially Modulated Optical Properties.” <i>Light: Science &#38; Applications</i>, vol. 15, 145, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41377-025-02166-5\">10.1038/s41377-025-02166-5</a>.","apa":"Salamin, Y., Yang, G., Mills, B., Grossi Fonseca, A., Roques-Carmes, C., Yang, Q., … Soljačić, M. (2026). Three-dimensional nanophotonics with spatially modulated optical properties. <i>Light: Science &#38; Applications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41377-025-02166-5\">https://doi.org/10.1038/s41377-025-02166-5</a>","ieee":"Y. Salamin <i>et al.</i>, “Three-dimensional nanophotonics with spatially modulated optical properties,” <i>Light: Science &#38; Applications</i>, vol. 15. Springer Nature, 2026.","ama":"Salamin Y, Yang G, Mills B, et al. Three-dimensional nanophotonics with spatially modulated optical properties. <i>Light: Science &#38; Applications</i>. 2026;15. doi:<a href=\"https://doi.org/10.1038/s41377-025-02166-5\">10.1038/s41377-025-02166-5</a>"},"_id":"21537","title":"Three-dimensional nanophotonics with spatially modulated optical properties","OA_place":"publisher","OA_type":"gold","date_updated":"2026-04-27T07:59:10Z","day":"03","DOAJ_listed":"1","author":[{"first_name":"Yannick","last_name":"Salamin","full_name":"Salamin, Yannick"},{"full_name":"Yang, Gaojie","last_name":"Yang","first_name":"Gaojie"},{"full_name":"Mills, Brian","last_name":"Mills","first_name":"Brian"},{"last_name":"Grossi Fonseca","first_name":"André","full_name":"Grossi Fonseca, André"},{"id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles","last_name":"Roques-Carmes","first_name":"Charles"},{"last_name":"Yang","first_name":"Quansan","full_name":"Yang, Quansan"},{"last_name":"Beroz","first_name":"Justin","full_name":"Beroz, Justin"},{"full_name":"Kooi, Steven E.","first_name":"Steven E.","last_name":"Kooi"},{"last_name":"de Miguel Comella","first_name":"Marc","full_name":"de Miguel Comella, Marc"},{"first_name":"Kiran","last_name":"Mak","full_name":"Mak, Kiran"},{"first_name":"Sachin","last_name":"Vaidya","full_name":"Vaidya, Sachin"},{"first_name":"Daniel","last_name":"Oran","full_name":"Oran, Daniel"},{"last_name":"Swain","first_name":"Corban","full_name":"Swain, Corban"},{"full_name":"Sun, Yi","last_name":"Sun","first_name":"Yi"},{"first_name":"Shai","last_name":"Maayani","full_name":"Maayani, Shai"},{"full_name":"Sloan, Jamison","last_name":"Sloan","first_name":"Jamison"},{"full_name":"Amin Elfadil Elawad, Amel","first_name":"Amel","last_name":"Amin Elfadil Elawad"},{"full_name":"Lopez, Josue J.","first_name":"Josue J.","last_name":"Lopez"},{"full_name":"Boyden, Edward S.","first_name":"Edward S.","last_name":"Boyden"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}],"publication_status":"published","pmid":1,"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_number":"145","external_id":{"pmid":[" 41775693"]},"intvolume":"        15","language":[{"iso":"eng"}],"oa":1,"date_created":"2026-03-30T12:22:47Z","date_published":"2026-03-03T00:00:00Z","year":"2026","article_type":"original","volume":15,"month":"03","abstract":[{"text":"Nanophotonics has revolutionized the control of light-matter interactions in various fields of fundamental science and technology. In this work, we propose Implosion Fabrication (ImpFab) as a versatile nanophotonics fabrication platform providing the highest spatial resolution, material versatility, and full volumetric control. ImpFab uniquely combines top-down lithography with bottom-up nanoparticle assembly within a hydrogel scaffold, enabling precise control over optical material properties, such as refractive index, by adjusting printing parameters. We showcase the potential of ImpFab by fabricating three-dimensional photonic crystals and quasicrystals, as well as demonstrating optical structures with spatially modulated unit cell material properties. Our results highlight the potential of ImpFab in producing nanostructures with tailored optical functionalities, which are crucial for applications in sensing, imaging, and information processing, and opening new avenues in developing non-Hermitian photonic systems with spatially controlled gain and loss.","lang":"eng"}]},{"day":"12","date_updated":"2026-04-27T08:34:51Z","OA_type":"hybrid","OA_place":"publisher","title":"On-chip laser-driven free-electron spin polarizer","_id":"21555","publication":"Physical Review Letters","citation":{"short":"C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D.A.B. Miller, O. Solgaard, Physical Review Letters 136 (2026).","chicago":"Woodahl, Clarisse, Melanie Murillo, Charles Roques-Carmes, Aviv Karnieli, David A. B. Miller, and Olav Solgaard. “On-Chip Laser-Driven Free-Electron Spin Polarizer.” <i>Physical Review Letters</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/3c1m-d3hh\">https://doi.org/10.1103/3c1m-d3hh</a>.","ista":"Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O. 2026. On-chip laser-driven free-electron spin polarizer. Physical Review Letters. 136(6), 063802.","ama":"Woodahl C, Murillo M, Roques-Carmes C, Karnieli A, Miller DAB, Solgaard O. On-chip laser-driven free-electron spin polarizer. <i>Physical Review Letters</i>. 2026;136(6). doi:<a href=\"https://doi.org/10.1103/3c1m-d3hh\">10.1103/3c1m-d3hh</a>","ieee":"C. Woodahl, M. Murillo, C. Roques-Carmes, A. Karnieli, D. A. B. Miller, and O. Solgaard, “On-chip laser-driven free-electron spin polarizer,” <i>Physical Review Letters</i>, vol. 136, no. 6. American Physical Society, 2026.","mla":"Woodahl, Clarisse, et al. “On-Chip Laser-Driven Free-Electron Spin Polarizer.” <i>Physical Review Letters</i>, vol. 136, no. 6, 063802, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/3c1m-d3hh\">10.1103/3c1m-d3hh</a>.","apa":"Woodahl, C., Murillo, M., Roques-Carmes, C., Karnieli, A., Miller, D. A. B., &#38; Solgaard, O. (2026). On-chip laser-driven free-electron spin polarizer. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/3c1m-d3hh\">https://doi.org/10.1103/3c1m-d3hh</a>"},"main_file_link":[{"url":"https://doi.org/10.1103/3c1m-d3hh","open_access":"1"}],"publisher":"American Physical Society","type":"journal_article","extern":"1","article_processing_charge":"No","ddc":["530"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","scopus_import":"1","doi":"10.1103/3c1m-d3hh","publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"quality_controlled":"1","status":"public","abstract":[{"lang":"eng","text":"Spin-polarized electron beam sources enable studies of spin-dependent electric and magnetic effects at the nanoscale. We propose a method of creating spin-polarized electrons on an integrated photonics chip by laser-driven nanophotonic fields. A two-stage interaction separated by a free-space drift length is proposed, where the first stage and drift length introduces spin-dependent characteristics into the probability distribution of the electron wave function. The second stage uses an adjusted optical near field to rotate the spin states utilizing the spin-dependent wave-packet distribution to produce electrons with high ensemble average spin expectation values. This platform provides an integrated and compact method to generate spin-polarized electrons, implementable with millimeter scale chips and tabletop lasers."}],"month":"02","volume":136,"date_published":"2026-02-12T00:00:00Z","article_type":"original","year":"2026","date_created":"2026-03-30T12:22:47Z","language":[{"iso":"eng"}],"oa":1,"issue":"6","intvolume":"       136","publication_status":"published","article_number":"063802","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"author":[{"first_name":"Clarisse","last_name":"Woodahl","full_name":"Woodahl, Clarisse"},{"first_name":"Melanie","last_name":"Murillo","full_name":"Murillo, Melanie"},{"last_name":"Roques-Carmes","first_name":"Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82","full_name":"Roques-Carmes, Charles"},{"last_name":"Karnieli","first_name":"Aviv","full_name":"Karnieli, Aviv"},{"last_name":"Miller","first_name":"David A. B.","full_name":"Miller, David A. B."},{"full_name":"Solgaard, Olav","first_name":"Olav","last_name":"Solgaard"}]},{"date_created":"2026-03-30T12:22:48Z","title":"Supercollimating photonic crystal scintillators","_id":"21581","date_published":"2026-02-01T00:00:00Z","year":"2026","publisher":"SPIE","publication":"High Contrast Metastructures XV","language":[{"iso":"eng"}],"citation":{"chicago":"Vaidya, Sachin, Seou Choi, Charles Roques-Carmes, and Marin Soljačić. “Supercollimating Photonic Crystal Scintillators.” In <i>High Contrast Metastructures XV</i>, Vol. PC13910. SPIE, 2026. <a href=\"https://doi.org/10.1117/12.3079431\">https://doi.org/10.1117/12.3079431</a>.","ista":"Vaidya S, Choi S, Roques-Carmes C, Soljačić M. 2026. Supercollimating photonic crystal scintillators. High Contrast Metastructures XV. OPTO vol. PC13910, PC1391008.","short":"S. Vaidya, S. Choi, C. Roques-Carmes, M. Soljačić, in:, High Contrast Metastructures XV, SPIE, 2026.","ieee":"S. Vaidya, S. Choi, C. Roques-Carmes, and M. Soljačić, “Supercollimating photonic crystal scintillators,” in <i>High Contrast Metastructures XV</i>, San Francisco, CA, United States, 2026, vol. PC13910.","mla":"Vaidya, Sachin, et al. “Supercollimating Photonic Crystal Scintillators.” <i>High Contrast Metastructures XV</i>, vol. PC13910, PC1391008, SPIE, 2026, doi:<a href=\"https://doi.org/10.1117/12.3079431\">10.1117/12.3079431</a>.","apa":"Vaidya, S., Choi, S., Roques-Carmes, C., &#38; Soljačić, M. (2026). Supercollimating photonic crystal scintillators. In <i>High Contrast Metastructures XV</i> (Vol. PC13910). San Francisco, CA, United States: SPIE. <a href=\"https://doi.org/10.1117/12.3079431\">https://doi.org/10.1117/12.3079431</a>","ama":"Vaidya S, Choi S, Roques-Carmes C, Soljačić M. Supercollimating photonic crystal scintillators. In: <i>High Contrast Metastructures XV</i>. Vol PC13910. SPIE; 2026. doi:<a href=\"https://doi.org/10.1117/12.3079431\">10.1117/12.3079431</a>"},"month":"02","day":"01","abstract":[{"text":"We demonstrate that nanophotonic scintillators based on three-dimensional (3D) photonic crystals can overcome the longstanding tradeoff between spatial resolution and light yield in X-ray imaging. By engineering supercollimation, which is light propagation without angular spreading, within the emission spectrum, we strongly shape the angular emission profile of the scintillator, dramatically reducing blurring at large thicknesses. Our theoretical and numerical results, using realistic scintillator and photonic crystal parameters, show that this improves the Detector Quantum Efficiency (DQE) by up to several orders of magnitude at high spatial frequencies, enabling sharper images and reduced X-ray dosages. This approach offers a new path toward high-resolution, low-dose X-ray imaging systems.","lang":"eng"}],"OA_type":"closed access","volume":"PC13910","date_updated":"2026-05-05T10:53:00Z","conference":{"end_date":"2026-01-23","location":"San Francisco, CA, United States","start_date":"2026-01-17","name":"OPTO"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"None","status":"public","doi":"10.1117/12.3079431","quality_controlled":"1","publication_status":"published","article_number":"PC1391008 ","article_processing_charge":"No","extern":"1","type":"conference","author":[{"full_name":"Vaidya, Sachin","first_name":"Sachin","last_name":"Vaidya"},{"full_name":"Choi, Seou","last_name":"Choi","first_name":"Seou"},{"first_name":"Charles","last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82"},{"full_name":"Soljačić, Marin","last_name":"Soljačić","first_name":"Marin"}]},{"title":"Experimental observation of energy-band Riemann surface","_id":"21583","OA_place":"publisher","main_file_link":[{"url":"https://doi.org/10.1126/sciadv.aec8239","open_access":"1"}],"publisher":"American Association for the Advancement of Science","publication":"Science Advances","citation":{"ista":"Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. 2026. Experimental observation of energy-band Riemann surface. Science Advances. 12(12), eaec8239.","chicago":"Cheng, Dali, Heming Wang, Janet Zhong, Eran Lustig, Charles Roques-Carmes, and Shanhui Fan. “Experimental Observation of Energy-Band Riemann Surface.” <i>Science Advances</i>. American Association for the Advancement of Science, 2026. <a href=\"https://doi.org/10.1126/sciadv.aec8239\">https://doi.org/10.1126/sciadv.aec8239</a>.","short":"D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, S. Fan, Science Advances 12 (2026).","mla":"Cheng, Dali, et al. “Experimental Observation of Energy-Band Riemann Surface.” <i>Science Advances</i>, vol. 12, no. 12, eaec8239, American Association for the Advancement of Science, 2026, doi:<a href=\"https://doi.org/10.1126/sciadv.aec8239\">10.1126/sciadv.aec8239</a>.","apa":"Cheng, D., Wang, H., Zhong, J., Lustig, E., Roques-Carmes, C., &#38; Fan, S. (2026). Experimental observation of energy-band Riemann surface. <i>Science Advances</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/sciadv.aec8239\">https://doi.org/10.1126/sciadv.aec8239</a>","ieee":"D. Cheng, H. Wang, J. Zhong, E. Lustig, C. Roques-Carmes, and S. Fan, “Experimental observation of energy-band Riemann surface,” <i>Science Advances</i>, vol. 12, no. 12. American Association for the Advancement of Science, 2026.","ama":"Cheng D, Wang H, Zhong J, Lustig E, Roques-Carmes C, Fan S. Experimental observation of energy-band Riemann surface. <i>Science Advances</i>. 2026;12(12). doi:<a href=\"https://doi.org/10.1126/sciadv.aec8239\">10.1126/sciadv.aec8239</a>"},"day":"18","OA_type":"gold","date_updated":"2026-04-27T10:01:35Z","oa_version":"Published Version","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","doi":"10.1126/sciadv.aec8239","publication_identifier":{"issn":["2375-2548"]},"quality_controlled":"1","arxiv":1,"article_processing_charge":"No","type":"journal_article","extern":"1","date_created":"2026-03-30T12:22:48Z","date_published":"2026-03-18T00:00:00Z","article_type":"original","year":"2026","intvolume":"        12","language":[{"iso":"eng"}],"issue":"12","oa":1,"month":"03","abstract":[{"lang":"eng","text":"Non-Hermiticity naturally arises in physical systems that exchange energy with their environment. The presence of non-Hermiticity leads to many topological physics phenomena and device applications. In the non-Hermitian energy band theory, the foundation of these physics and applications, both energies and wave vectors take complex values. The energy bands thus become a Riemann surface, and such an energy-band Riemann surface underlies all important signatures of non-Hermitian topology. Despite a long history and recent theoretical interests, the energy-band Riemann surface has not been experimentally studied. Here, we provide a photonic observation of the energy-band Riemann surface of a non-Hermitian system. This is achieved by a tunable imaginary gauge transformation in photonic synthetic frequency dimensions. From measured topologies of the Riemann surface, we reveal the complex-energy winding, the open-boundary-condition spectrum, the generalized Brillouin zone, and the branch points. Our findings demonstrate a unified framework in the studies of diverse effects in non-Hermitian topological physics through an experimental observation of energy-band Riemann surfaces."}],"volume":12,"DOAJ_listed":"1","publication_status":"published","article_number":"eaec8239","external_id":{"arxiv":["2510.08819"]},"author":[{"full_name":"Cheng, Dali","first_name":"Dali","last_name":"Cheng"},{"full_name":"Wang, Heming","first_name":"Heming","last_name":"Wang"},{"last_name":"Zhong","first_name":"Janet","full_name":"Zhong, Janet"},{"full_name":"Lustig, Eran","last_name":"Lustig","first_name":"Eran"},{"first_name":"Charles","last_name":"Roques-Carmes","full_name":"Roques-Carmes, Charles","id":"e2e68fc9-6505-11ef-a541-eb4e72cc3e82"},{"full_name":"Fan, Shanhui","first_name":"Shanhui","last_name":"Fan"}]},{"date_updated":"2026-04-15T08:45:19Z","day":"04","alternative_title":["ISTA Thesis"],"file":[{"access_level":"closed","date_created":"2026-04-03T17:28:48Z","relation":"source_file","content_type":"application/x-zip-compressed","file_size":139353434,"creator":"mbaig","checksum":"c3986dba90653dac97adba662ebff238","file_id":"21655","date_updated":"2026-04-13T08:24:13Z","file_name":"PhD-Thesis-Mirza-Ahad-Baig - Library Submission.zip"},{"file_size":1942037,"content_type":"application/pdf","creator":"mbaig","access_level":"open_access","relation":"main_file","date_created":"2026-04-03T17:29:30Z","date_updated":"2026-04-15T07:37:25Z","file_name":"2026_Baig_Mirza_Ahad_Thesis.pdf","file_id":"21656","checksum":"292a5989262521f7c145a109d1f348cb"}],"publisher":"Institute of Science and Technology Austria","department":[{"_id":"GradSch"},{"_id":"KrPi"}],"has_accepted_license":"1","citation":{"short":"M.A. Baig, On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting, Institute of Science and Technology Austria, 2026.","ista":"Baig MA. 2026. On secure chain selection rules from physical resources in a permissionless setting. Institute of Science and Technology Austria.","chicago":"Baig, Mirza Ahad. “On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21651\">https://doi.org/10.15479/AT-ISTA-21651</a>.","ama":"Baig MA. On secure chain selection rules from physical resources in a permissionless setting. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21651\">10.15479/AT-ISTA-21651</a>","apa":"Baig, M. A. (2026). <i>On secure chain selection rules from physical resources in a permissionless setting</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21651\">https://doi.org/10.15479/AT-ISTA-21651</a>","mla":"Baig, Mirza Ahad. <i>On Secure Chain Selection Rules from Physical Resources in a Permissionless Setting</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21651\">10.15479/AT-ISTA-21651</a>.","ieee":"M. A. Baig, “On secure chain selection rules from physical resources in a permissionless setting,” Institute of Science and Technology Austria, 2026."},"title":"On secure chain selection rules from physical resources in a permissionless setting","_id":"21651","OA_place":"publisher","supervisor":[{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Pietrzak, Krzysztof Z","orcid":"0000-0002-9139-1654","last_name":"Pietrzak","first_name":"Krzysztof Z"}],"degree_awarded":"PhD","ddc":["000"],"article_processing_charge":"No","type":"dissertation","status":"public","doi":"10.15479/AT-ISTA-21651","publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-078-7"]},"oa_version":"Published Version","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","related_material":{"record":[{"relation":"part_of_dissertation","id":"21134","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"20587"}]},"month":"03","abstract":[{"lang":"eng","text":"Blockchains enable distributed consensus in permissionless settings, where participants\r\nare unknown, dynamically changing, and do not trust each other. While Bitcoin,\r\nbased on Proof-of-Work (PoW), was the first protocol in this model, significant\r\nresearch has focused on permissionless protocols using alternative physical resources,\r\nspecifically Proof-of-Space (PoSpace) and Verifiable Delay Functions (VDFs). This\r\nthesis investigates the theoretical limits and design space of longest-chain protocols in\r\nthe fully permissionless and dynamically available settings using these three resources.\r\nFirst, we address the feasibility of blockchains relying solely on storage as a resource.\r\nWe prove a fundamental impossibility result: there exists no secure longest-chain\r\nprotocol based exclusively on Proof-of-Space in the fully permissionless or dynamically\r\navailable settings. Further, we quantify the adversarial capabilities required to execute\r\na double-spend attack. Our result formally justifies the necessity of coupling PoSpace\r\nwith time-dependent primitives (such as VDFs) or to move to less permissive settings\r\n(quasi-permissionless or permissioned) to ensure security.\r\nSecond, we generalize Nakamoto-like heaviest chain consensus to protocols utilizing\r\ncombinations of multiple physical resources. We analyze chain selection rules governed\r\nby a weight function Γ(S, V,W), which assigns weight to blocks based on recorded\r\nSpace (S), VDF speed (V ), and Work (W). We provide a complete classification\r\nof secure weight functions, proving that a weight function is secure against private\r\ndouble-spend attacks if and only if it is homogeneous in the timed resources (V,W)\r\nand sub-homogeneous in S. This framework unifies existing protocols like Bitcoin and\r\nChia under a single theoretical model and provides a powerful tool for designing new\r\nlongest-chain blockchains from a mix of physical resources."}],"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","oa":1,"language":[{"iso":"eng"}],"date_created":"2026-04-02T09:31:34Z","file_date_updated":"2026-04-15T07:37:25Z","date_published":"2026-03-04T00:00:00Z","year":"2026","author":[{"full_name":"Baig, Mirza Ahad","id":"3EDE6DE4-AA5A-11E9-986D-341CE6697425","first_name":"Mirza Ahad","last_name":"Baig"}],"publication_status":"published","tmp":{"name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png"},"corr_author":"1"},{"DOAJ_listed":"1","project":[{"grant_number":"101034413","call_identifier":"H2020","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"corr_author":"1","article_number":"e2025MS005343","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"publication_status":"published","author":[{"full_name":"Takasuka, Daisuke","first_name":"Daisuke","last_name":"Takasuka"},{"last_name":"Becker","first_name":"Tobias","full_name":"Becker, Tobias"},{"last_name":"Bao","first_name":"Jiawei","id":"bb9a7399-fefd-11ed-be3c-ae648fd1d160","full_name":"Bao, Jiawei"}],"article_type":"original","year":"2026","file_date_updated":"2026-04-07T09:11:23Z","date_published":"2026-03-01T00:00:00Z","date_created":"2026-04-05T22:01:31Z","issue":"3","language":[{"iso":"eng"}],"oa":1,"acknowledgement":"We thank Peter Bechtold, Lukas Brunner, Peter Dueben, Richard Forbes, Estibaliz Gascon, and Benoit Vanniere for providing insightful comments on the present study. We also thank Sebastian Milinski, Xabier Pedruzo and Thomas Rackow for their contributions to setting up IFS-FESOM for nextGEMS. We are also grateful to Dr. Walter Hannah and an anonymous reviewer for their constructive comments, which improved the original version of the manuscript. D. Takasuka was supported by JSPS KAKENHI Grants 20H05728 and 24K22893 and by JSPS Core-to-Core Program, “International Core-to-Core Project on Global Storm Resolving Analysis” (Grant Number: JPJSCCA20220001). T. Becker was supported by the Horizon 2020 project nextGEMS under grant agreement number 101003470. J. Bao acknowledges funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant (grant agreement No 101034413). The ICON and IFS simulations were performed with supercomputing resources of the German Climate Computing Centre (Deutsches Klimarechenzentrum, DKRZ) granted by its Scientific Steering Committee (WLA) under project ID 1235. The NICAM simulation was performed on the supercomputer Fugaku (proposal numbers hp220132, hp230078, hp230108, hp230278, and hp240267).","intvolume":"        18","abstract":[{"text":"We compare three global kilometer-scale models (ICON, IFS and NICAM) to clarify the advantages and challenges of high-resolution global weather and climate modeling, using different approaches to represent convection, from fully parameterized to fully explicit. Our analysis focuses on tropical precipitation characteristics spanning a wide range of spatio-temporal scales—including the diurnal cycle, extreme precipitation, convective organization, and the Madden-Julian Oscillation (MJO)—along with interactions between convection and the thermodynamic environment. All three models commonly show weaker convective organization with smaller precipitation cells than observed, though the strength of the bias varies by model. This diversity is introduced by differences in the representation of (a) convective initiation affected by the convective sensitivity to moisture and (b) tropospheric moistening associated with deep convection. Models with stronger thermodynamic-convection coupling increase environmental moisture near convection, thereby enhancing convective organization. This has important upscale effects on the MJO; while IFS and NICAM capture its eastward propagation well, ICON has difficulty reproducing it. The amplitudes and phases of precipitation diurnal cycles over land show much greater disagreement among the models than over ocean, influenced by how convection is initiated. Biases in rain evaporation and cold pool formation hinder the propagation of mesoscale convection, leading to errors such as the misrepresentation of nocturnal convection moving off the coast of Sumatra in IFS and ICON. These results highlight the importance of thermodynamic-convection coupling in realistically simulating tropical convection across scales. To improve this coupling, kilometer-scale models require better representation of the interaction between resolved convection and three-dimensional turbulent mixing.","lang":"eng"}],"month":"03","volume":18,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":"1","oa_version":"Published Version","quality_controlled":"1","doi":"10.1029/2025MS005343","publication_identifier":{"eissn":["1942-2466"]},"ec_funded":1,"status":"public","type":"journal_article","article_processing_charge":"Yes","ddc":["550"],"OA_place":"publisher","_id":"21657","title":"Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations","citation":{"ista":"Takasuka D, Becker T, Bao J. 2026. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. Journal of Advances in Modeling Earth Systems. 18(3), e2025MS005343.","chicago":"Takasuka, Daisuke, Tobias Becker, and Jiawei Bao. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>.","short":"D. Takasuka, T. Becker, J. Bao, Journal of Advances in Modeling Earth Systems 18 (2026).","apa":"Takasuka, D., Becker, T., &#38; Bao, J. (2026). Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2025MS005343\">https://doi.org/10.1029/2025MS005343</a>","mla":"Takasuka, Daisuke, et al. “Precipitation Characteristics and Thermodynamic-Convection Coupling in Global Kilometer-Scale Simulations.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3, e2025MS005343, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>.","ieee":"D. Takasuka, T. Becker, and J. Bao, “Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 3. Wiley, 2026.","ama":"Takasuka D, Becker T, Bao J. Precipitation characteristics and thermodynamic-convection coupling in global kilometer-scale simulations. <i>Journal of Advances in Modeling Earth Systems</i>. 2026;18(3). doi:<a href=\"https://doi.org/10.1029/2025MS005343\">10.1029/2025MS005343</a>"},"publication":"Journal of Advances in Modeling Earth Systems","has_accepted_license":"1","publisher":"Wiley","department":[{"_id":"CaMu"}],"file":[{"success":1,"checksum":"ca7dac4bab31348d0640ed22580c6dce","file_id":"21665","file_name":"2026_JAMES_Takasuka.pdf","date_updated":"2026-04-07T09:11:23Z","date_created":"2026-04-07T09:11:23Z","relation":"main_file","access_level":"open_access","creator":"dernst","content_type":"application/pdf","file_size":3854313}],"day":"01","date_updated":"2026-06-16T10:43:35Z","OA_type":"gold"}]